Gene Spk207 (Sea Urchin)

Spk207

Species: Sea Urchin
Alias: Spk207, SPU_010964
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: urch
Subfamily: urchB

Sequence

Name Sequence Type Origin Length Description Download
Spk207.AA Protein None 791 None Fasta, JSON
Spk207.kin_dom Protein Kinase Domain None 211 None Fasta, JSON

Protein domain

Protein domains of Spk207.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Spk207.AA urchB 334-544 81 5e-197 660.84 In-house 1-212 (212) Show / Hide 
Range on Protein: 334-544
Range on HMM: 1-212/212
Sequence Identity: 81% (172 aa)

INTLQEIGRGSYGRVVIARHRSTGVPLAIKEPSWSDDFASPGEMVEELK-ATRTRATKEAMIQQLLSGSPYFPKFWGTLDLGNELCQAVEFVGCKKTGTG
||.|||||||.||||||||||.|.||||||.|.|||...||.|||.||. |||||.||||||.||.|.||||||||||||..|.||||.|||||||||.|
INDLQEIGRGTYGRVVIARHRQTKVPLAIKQPCWSDNYQSPNEMVDELHDATRTRVTKEAMIHQLMSDSPYFPKFWGTLDIDNDLCQAQEFVGCKKTGIG

YPLHEPPSLSMCNVVKIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGKRYNAVIIDYGMASSITAPPKMVGVTKEVKMAYVHGGEADYITPEVVLDEQ
|||||||.|||||||.|||||||||||||||||||||||||||||||||.||.|||||.||.|.||||.|||.|.||.|||||||.|||||.|||.|..|
YPLHEPPPLSMCNVVDIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGHRYHAVIIDFGMVSTITAPLKMVEVPKELKMAYVHGEEADYIAPEVILHGQ

PTSIASDVFSVG
.|||.|||||||
STSISSDVFSVG
Kinase Spk207.AA urch 340-544 53 1.3e-129 436.86 In-house 1-217 (217) Show / Hide 
Range on Protein: 340-544
Range on HMM: 1-217/217
Sequence Identity: 53% (116 aa)

IGRGSYGRVVIARHRSTGVPLAIKEPSWSDDFASPGEMVEELK-ATRTRATKEAMIQQLLSGSPYFPKFWGTLDLGNELCQAVEFVGCKKTGTGYPLHEP
||||.||||...|||.|..|.|||.|.|........||..| . |...|.|||||..||.||.||||||.|..|....||...||.|.||||. ||||..
IGRGTYGRVHLYRHRQTKQPVAIKMPCWPQNYTDMNEMEMEEWKANHERFTKEAMVHQLMSGHPYFPKFYGCVDIDDDLCLVMEFIGDKKTGKSYPLHWC

PS----------LSMCNVVKIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGK-RYNAVIIDYGMASSITAPPKMVGVTKEVKMAYVHGGEADYITPEV
..          ||..|...||||||.|||..||||.||||||.|||||||||. |..|||||.|... .|.|.||.....|....|.||.....| ||.
IHKSRMCMPNPHLSKWNWLNIAEDIVHGMMAMHDHGFLHNDLKEDNVLLEKRGHGRWHAVIIDFGWVCTMTMPFKMMHFPDEEMREYMHGHGYCHIAPEC

VLDEQPTSIASDVFSVG
|||.||.||||||.|||
VLDGQPCSIASDVYSVG
Kinase Spk207.AA urch-unclassified 340-544 35 1.1e-67 231.21 In-house 1-215 (215) Show / Hide 
Range on Protein: 340-544
Range on HMM: 1-215/215
Sequence Identity: 35% (77 aa)

IGRGSYGRVVIARHRSTGVPLAIK-EPSWSDDFASPGEMVEELKATRTRATKEAMIQQLLSGSPYFPKFWGTLDLGNELCQAVEFVGCKKTGTGYPL---
|| |..|.|   ||  . || ..|  .  . |  .  .|. . ..   |..||||...|....||||.  |  .... .| ..|| | |.|.| |||   
IGKGTFGKVFMMRHQREAVPVKVKMIHEHHNDYDYEMRMQ-NKLLMHERIMKEAMVHRLFADHPYFPRCYGMVKHEDCPCIVMEFLGDKQTYTVYPLCQW

--HEP---PSLSMCNVVKIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGK--RYNAVIIDYGMASSITAPPKMVGVTKEVKMAYVHGGEADYITPEVV
   .    | ||  .   |..||..||.. |. .||||||| .|.||.....  |  | ||| ||.| .| | |    . . .  |  |    .. ||.|
IHERHKSNPALSKHHWINICMDICHGMHAMHEMDLLHNDLKSNNILLQWCDHDQRWHAYIIDFGMISTMTMPHKQRNFSDHEMREYMMGKIYHHMAPEIV

LDEQPTSIASDVFSVG
|. ||||..||..| |
LYGQPTSVYSDIYSLG
Kinase Spk207.AA urchC 335-547 38 7.1e-65 208.95 In-house 2-223 (223) Show / Hide 
Range on Protein: 335-547
Range on HMM: 2-223/223
Sequence Identity: 38% (88 aa)

NTLQEIGRGSYGRVVIARHRSTGVPLAIKEPSWSDDFASPGEMVE-ELKATRTRATKEAMIQQLLSGSPYFPKFWGTLDLGNELCQAVEFVGCKKTGTGY
. | .||.||||.|  .|      | |||.|     |   .|  | | |.   | .|||.. |..|..||||.. ||. .. ..|   ||.| |..|  |
TILEMIGKGSYGEVMLGRLNGEKDPVAIKRPYVPQHFT--PEKEESEWKQNNGRCEKEARVGQMMSTCPYFPRMYGTVMIDENMCIVTEFIGDKQQGKVY

PLHEPPS----------LSMCNVVKIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGKRYNAVIIDYGMASSITAPPKMVGVTKEVKMAYVHGGE-ADY
.||.             ..  | | |||||..| .  || |||||| | |||||| |. |  ..||| || | .. || . |  .   |     .    .
MLHDAMCPRKGCDPIPYVQKWNMVAIAEDIIRGVHFMHDFGLLHNDIKDDNVLLEHRKERWHGCIIDMGMVSTMAYPPHQRG--FNDVMPDHQKLYGFIH

ITPEVVL-DEQPTSIASDVFSVGRIF
| |||.  |   .| |||..||| | 
IAPEVLDIDGCQVSVASDIYSVGVIL
Kinase Spk207.AA urchA 340-541 31 1.9e-45 144.63 In-house 1-208 (208) Show / Hide 
Range on Protein: 340-541
Range on HMM: 1-208/208
Sequence Identity: 31% (69 aa)

IGRGSYGRVVIARHRSTGVPLAIKEPSWSDDFASPGEMVEELKATRTRATKEAMIQQLLSGSPYFPKFWGTLDL-GNELCQAVEFVGCKKTGTG----YP
 ||| || |   ||| |. | |.|       .. |.|...  . . .   .|. |.|.|...|.||.| | ... .     | ||.|   ||        
LGRGVYGTVHLYRHRQTDHPVALKV------IELPKEYKKMRR-KIECFQNEMQIHQVLGCEPWFPTFYGCCEICEDKVGMAMEFCGDEMTGESYTITWC

LHE-----PPSLSMCNVVKIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEK-RGKRYNAVIIDYGMASSITAPP---KMVGVTKEVKMAYVHGGEADYITP
|        | |.     ... || .|    |. | | ||||.||.|. |  . |  |.||| | |. . .|     |   ... |  |  ..   .| |
LDKAMEMRQPALTRDQWMNVMLDIAEGLKVMHEKGFLCNDLKEDNCLVRKTEFGRWRAKIIDFGWACPCQMPFPACRMH-FDQRQKQFYRYCHRCCHIAP

EVVLDEQPTSIASDVF
| .||.|| |..|||.
ECALDAQPCSTSSDVY
Kinase Spk207.AA S_TKc 334-598 17 9.1e-14 24.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 334-598
Range on HMM: 1-231/231
Sequence Identity: 17% (50 aa)

INTLQEIGRGSYGRVVIARHRSTGVPLAIKEPSWSDDFASPGEMVEELKATRTRATKEAMIQQLLSGSPYFPKFWGTLDLGNELCQAVEFVGC--KKTGT
   |..||.|..|.|  .||..||   |||. .                    .. .|  | .   . |.  |. .. .  ..|.   |...       .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFD

GYPLHEPPS----LSMCNVVKIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGKRYNAVIIDYGMASSITAPPKMVGVTKEVKMAYVHGGEADYITPEV
    . ..     ..   . ...  |....   |.|| .| ||| .|.|| .     .  |.| |.|  .                .   |  .|. |||
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----------------TTFCGTPWYMAPEV

VLDEQPTSI-ASDVFSVGRIFSDMGE---IFGGKNEYHTCHRFPVVRELSKLGAQCMADNPDHRPSLDTIKS--------QIT
.    . .  ..|. |.| |.  |      |   ... . ..    .|.  .  .|.  .|..||.   .          .  
L----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Spk207.AA Pkinase 334-544 19 3.3e-12 44.26 Pfam 1-199 (293) Show / Hide 
Range on Protein: 334-544
Range on HMM: 1-199/293
Sequence Identity: 19% (44 aa)

INTLQEIGRGSYGRVVIARHRSTGVPLAIKEPSWSDDFASPGEMVEELKATRTRATKEAMIQQLLSGSPYFPKFWGTLDLGNELCQAVEFVGCK----KT
. ... ||.||.|.| ...|..||   |.|.      .  ..|  ..... | .   |. | . | ..|.  .....   .....   |....       
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKI------IKKRHEKSWKDQTHRRL--SEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDL

G----TGYPLHEPPSL--SMCNVVKIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGKRYNA----VIIDYGMASSITAPPKMVGVTKEVKMAYVHGGE
     |    ..  ..  |.  . ...  |..|.   |..| .| ||| .|.|. ..|   .      |.| | |  .         .     ...  | 
FDYIST----WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNG---HIDACVKICDFGLAKQFD--------Y-NNS-MTTFCGT

ADYITPEVVLDEQPTSIASDVFSVG
 .|. |||... |. . ..|..|.|
PWYMAPEVIRGGQYYGPKVDMWSCG
Kinase Spk207.AA Ciliate-C7 441-498 37 2.8e-11 32.9 In-house 99-153 (164) Show / Hide 
Range on Protein: 441-498
Range on HMM: 99-153/164
Sequence Identity: 37% (22 aa)

LSMCNVVKIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGKRYNAVIIDYGMASSIT
|.  . .|.|.||  |. . |. ... |||| || |    |   |||..|.|.|  .|
LNEISAIKYAKDIAQGLYYIHSKNCVVNDLKMDNILIDYNG---NAVVCDFGLADNLT
Kinase Spk207.AA TKL 447-544 16 3e-09 29.48 In-house 135-276 (364) Show / Hide 
Range on Protein: 447-544
Range on HMM: 135-276/364
Sequence Identity: 16% (24 aa)

VKIAEDIVKGMMEFHDHG--------LLHNDLKNDNVLLEKRGK-----------RYNAVIIDYGMASSITAPPKMVGVTKEVK----------MAYVHG
...| || .||   | ..        ..| ||| .|.|. . ..            ... | |.| . ...   .|    . ..          . .  .
CRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQC

GEADYITPEVVLDEQPTSIAS---------------DVFSVG
|   .  |||  ...... ..               ||.| |
GTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFG
Kinase Spk207.AA LISK 339-364 50 2.9e-08 22.73 In-house 1-26 (296) Show / Hide 
Range on Protein: 339-364
Range on HMM: 1-26/296
Sequence Identity: 50% (13 aa)

EIGRGSYGRVVIARHRSTGVPLAIKE
|||.|..| |.  .|| || . |||.
EIGKGFFGKVYKGTHRQTGQVMAIKM
Kinase Spk207.AA CAMK 339-363 29 8.4e-08 20.46 In-house 1-37 (425) Show / Hide 
Range on Protein: 339-363
Range on HMM: 1-37/425
Sequence Identity: 29% (11 aa)

EIGRGSYGRVVIARHRSTG------------VPLAIK
..||||.| |  ..|..|.            .  |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIK
Kinase Spk207.AA STE 334-364 23 2e-06 19.05 In-house 1-46 (359) Show / Hide 
Range on Protein: 334-364
Range on HMM: 1-46/359
Sequence Identity: 23% (11 aa)

INTLQEIGRGSYGRVVIARHRS---------------TGVPLAIKE
   ...||.|..| |. |...                ||.  |||.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQ
Kinase Spk207.AA TKL 563-597 25 1.2e-05 16.26 In-house 330-364 (364) Show / Hide 
Range on Protein: 563-597
Range on HMM: 330-364/364
Sequence Identity: 25% (9 aa)

CHRFPVVRELSKLGAQCMADNPDHRPSLDTIKSQI
|.  .. ....||  .|.. .|. ||| ..|....
CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase Spk207.AA TyrKc 334-597 11 1.4e-05 -132.6 SMART 1-280 (280) Show / Hide 
Range on Protein: 334-597
Range on HMM: 1-280/280
Sequence Identity: 11% (41 aa)

INTLQEIGRGSYGRVVIARHRSTGVPLAIKEPSWSDDFASPGEMVEELKATRTR-------------ATKE--------------------AMIQQLLSG
|  ....|.| .|.|. .. .   .. |.|    .       .. .|..  .               .|..                    .  . | . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

SPYFPKFWGTLDLGNELCQAVEFVGCKKTGTGYPLHEPPSLSMCNVVKIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGKRYNAVIIDYGMASSITAP
 |                                      |.|   .... .| .||   |.... | ||   |.|. ...                   
RPK-------------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------

PKMVGVTKEVKMAY----VHGGEA-------DYITP-----EV-----------VLDEQPTSIASDVFS----------------VGRIF--SDMGEIFG
         || .       ...        ||...     .            ....   ...|||.|                 | |.   .  |.. 
--------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIE

GKNEYHTCHRFPV---------VRELSKLGAQCMADNPDHRPSLDTIKSQI
   . .   . |            |. ..  || . .|. ||.  .|....
YVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Spk207.AA STE 448-544 20 3.4e-05 14.42 In-house 155-255 (359) Show / Hide 
Range on Protein: 448-544
Range on HMM: 155-255/359
Sequence Identity: 20% (24 aa)

KIAEDIVKG-MMEFHDHGLLHNDLKNDNVLLEKRGKRYNAVIIDYGMASSITA-------------PPKMVGVTKEVKMAYVHGGEADYITPEVVLD---
.|. .|.|| .   |.|.  | |.| .|.||        . ..| | ....|                     |   |   . |    .  |||..    
YICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDFGVCGQLTDSMANIQSNNIIDCI-----ETMQQKRNTFVGTP--WMAPEVIQQNGQ

--EQPTSIASDVFSVG
  ... .. .|. |.|
GRDKGYDTKCDIWSLG
Kinase Spk207.AA LISK 447-494 36 3.7e-05 12.5 In-house 104-152 (296) Show / Hide 
Range on Protein: 447-494
Range on HMM: 104-152/296
Sequence Identity: 36% (18 aa)

VKIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKR-GKRYNAVIIDYGMA
|||| || .||   |. . .| |||  |.|. ..   .......| | |
VKIALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFA
Kinase Spk207.AA TKL 340-363 31 0.000196 11.89 In-house 1-32 (364) Show / Hide 
Range on Protein: 340-363
Range on HMM: 1-32/364
Sequence Identity: 31% (10 aa)

IGRGSYGRVVIARHRS--------TGVPLAIK
||.|..| |  ...|         || . |.|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVK
Kinase Spk207.AA CAMK 461-544 19 0.000374 8.49 In-house 196-321 (425) Show / Hide 
Range on Protein: 461-544
Range on HMM: 196-321/425
Sequence Identity: 19% (24 aa)

HDHGLLHNDLKNDNVLLEKRG--------------KRYNAVIIDYGMASSITAPPKMV--------------GVTKEVKMAYVHGGEADYIT-PEVVLD-
|.|.  | ||| .|.|| ...              ...|  ||| |.|  ..   .                  ..| .. .   |   |.  |||..  
HSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGK

------------EQPTSIASDVFSVG
            ... . ..|. |.|
GHCNMQNATDEEKPYYGPKCDMWSCG
Kinase Spk207.AA Pkinase_Tyr 334-363 26 0.006638 10.46 Pfam 1-34 (270) Show / Hide 
Range on Protein: 334-363
Range on HMM: 1-34/270
Sequence Identity: 26% (9 aa)

INTLQEIGRGSYGRVVIARHR----STGVPLAIK
|  ....|.|..|.|. .. .    .|..| |.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK
Kinase Spk207.AA Pkinase_Tyr 578-597 35 0.049328 7.51 Pfam 251-270 (270) Show / Hide 
Range on Protein: 578-597
Range on HMM: 251-270/270
Sequence Identity: 35% (7 aa)

QCMADNPDHRPSLDTIKSQI
||.. .|..||.   | .|.
QCWHYDPEDRPTFSEIHEQL
Kinase Spk207.AA Ciliate-C7 337-363 33 0.072099 2.32 In-house 1-27 (164) Show / Hide 
Range on Protein: 337-363
Range on HMM: 1-27/164
Sequence Identity: 33% (9 aa)

LQEIGRGSYGRVVIARHRSTGVPLAIK
.  .|.|..| |..|.  .| .  |||
FRFLGQGQQGLVLLAKDQKTNMRYAIK
TIM21 Spk207.AA TIM21 651-791 37 9.2e-63 219.62 Pfam 2-157 (157) Show / Hide 
Range on Protein: 651-791
Range on HMM: 2-157/157
Sequence Identity: 37% (58 aa)

VAQTSKDASYAGIIVLGVGITGLMFFTLGKELFSSDSPNSIYTKAYKVCKKNVEIQDAL--------GTPIKGYGEMTRRKR----RRHVSHLEYSQDGV
|. ......| .|...|||.||...... .||||..... |. .| . ...| ...|..        | .||.|||.|.| |    |.|||| .|  |||
VKEATQFTFYFIIVIGGVGVTGMVWYLIFWELFSPSGDTQIFNRAVEMVEENPRCRDVFQCNDGFHKGERIKAYGEETHRDRWTRNRPHVSHRKYDKDGV

SFMRMKFYLEG--PERKATVHLEMKKNES-GRYEYRYLFVELDGYPKRTIVLEDNR
  |.|.|..||  |....||||||..|.. . ||.||..|..| .....|..||||
EHMWMQFHVEGSEPRKQGTVHLEMVQNDQHWQYEWRYMYVQVDVPGHKRIYIEDNR