Gene FRAY (Sea Urchin)

FRAY

Species: Sea Urchin
Alias: Spk233, SPU_020611, FRAY
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: FRAY

Sequence

Name Sequence Type Origin Length Description Download
FRAY.AA Protein None 463 None Fasta, JSON
FRAY.kin_dom Protein Kinase Domain None 247 None Fasta, JSON

Protein domain

Protein domains of FRAY.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase FRAY.AA FRAY 4-250 63 1.3e-206 648.18 In-house 10-277 (277) Show / Hide 
Range on Protein: 4-250
Range on HMM: 10-277/277
Sequence Identity: 63% (171 aa)

GATATVHKAVCIPRDEECAIKRINLEKCN-TTMEELAKEIQAMCLCKHVNVVQYFTSFVVKDEIWLVMRLLEAGSCLDLIKYMMKKGK-GKGGLFEEAVI
||||.||||.||||.|.|||||||||||. |.|.||.|||||||.|.|.|||.|.|||||..|.|||||.||.|||||..|..|..|. .|.|.|.|.||
GATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHKQGVFDEHVI

ATILRETLQGLDYLHENGQLHRDIKAGNILLGSDGTVQLADFGVSSWIATGGDLSRDKVRTTFVGTPCWMAPEVMEQVTGYNFKADIWSFGILAIELATG
||||.|.|.||.|.|.|||.||||||||||.|.|||.|.||||||.|.||||||||..||.|||||||||||||||||.||.||||||||||.|||||||
ATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSFGITAIELATG

AAPYAKFPAMKESVLFL-------------------FRPTASKLLKSQFFKKPRNKPTASELLKSQFF
.|||.|.|.||...|.|                   ......|.......|.|...||||||||..||
KAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase FRAY.AA STE20 3-212 46 1.2e-112 380.59 In-house 9-234 (288) Show / Hide 
Range on Protein: 3-212
Range on HMM: 9-234/288
Sequence Identity: 46% (106 aa)

HGATATVHKAVCIPRDEE----CAIKRINLEKCN---TTMEELAKEIQAMCLCKHVNVVQYFTSFVVK----DEIWLVMRLLEAGSCLDLIKYMMKKGK-
.|.. .|.|| ..| .|.    .|||..|||||.     .|.. |||. |  ||| |.|.|..|....    ||.|.|| ....||..|..| .||.|| 
QGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMKHCMKCGKN

GKGG-LFEEAVIATILRETLQGLDYLHENGQLHRDIKAGNILLGSDGTVQLADFGVSSWIAT--GGDLSRDKVRTTFVGTPCWMAPEVMEQV----TGYN
.| |  ..|. ||.|.||.||||||||.|.. ||||||.||||..|| |.||||||.... .  . | .... | ||||||.||||||....     ||.
HK-GHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGR-D-TMQFKRNTFVGTPYWMAPEVIQCMEGPDKGYD

FKADIWSFGILAIELATGAAPYAKFPAMK
.|.||||.|| |||.|.|  ||.....|.
YKCDIWSLGITAIEMAEGEPPYFDMHPMR
Kinase FRAY.AA STE 3-250 29 3.3e-97 329.24 In-house 9-359 (359) Show / Hide 
Range on Protein: 3-250
Range on HMM: 9-359/359
Sequence Identity: 29% (104 aa)

HGATATVHKAVCI------PRDEE---------CAIKRINLEKCN----------------TTMEELAKEIQAMCLCK--HVNVVQYFTSFVVK------
.||. ||.||...      . .|.         .|||..|||.||                . |... |||. |  |.  | |.|.|. .....      
KGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKN

-DEIWLVMRLLEAGSCLDLIKYMMKKGK-------GKGGLFEEAVIATILRETLQG-LDYLHENGQLHRDIKAGNILLGSDGTVQLADFGVSSWIATGGD
 ||.|..| ....||. |.||  ...||       . .. |.| .||.|.|..|.| |.|||...  |||||..||||     | |.||||.. ..  ..
DDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQH-QHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMA

-----------LSRDKVRTTFVGTPCWMAPEVMEQ-----VTGYNFKADIWSFGILAIELATGAAPYAKFPAMKESVLFLFR------------------
           ..... |.|||||| ||||||..|     . ||..|.||||.|...||.|||  |..... |.   ...|                   
NIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPP

--------------------------PTASKLLKSQFFKKPRNKPTASELLK--SQFF
                          |     ..  . | |.. ||||.|||    |.
PLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase FRAY.AA YSK 22-218 45 1.3e-75 227.04 In-house 28-212 (257) Show / Hide 
Range on Protein: 22-218
Range on HMM: 28-212/257
Sequence Identity: 45% (91 aa)

AIKRINLEKCNTTMEELAKEIQAMCLCKHVNVVQYFTSFVVKDEIWLVMRLLEAGSCLDLIKY-MMKKGKGKGGLFEEAVIATILRETLQGLDYLHENGQ
||| |.||.     | ...|||    |.  .. .|. |.     .| .|  .  ||||||.|   .       | |.|  ||.|||| |.||||||..  
AIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYV-------GQFDEKYIAIILREILKGLDYLHSERK

LHRDIKAGNILLGSDGTVQLADFGVSSWIA-TGGDLSRDKVRTTFVGTPCWMAPEVMEQ-VTGYNFKADIWSFGILAIELATGAAPYAKFPAMKESVLFL
.|||||| |.||  .| | |.||||.. |  |       . | |||||| ||||||  | |..|.||||||| || |.|.|.|  ||..  .|.  |.||
IHRDIKAANVLLSEHGDVKLCDFGVAGQITDT------QIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPPYCDYHPMR--VMFL
Kinase FRAY.AA MST 9-211 42 4e-65 205.92 In-house 15-203 (254) Show / Hide 
Range on Protein: 9-211
Range on HMM: 15-203/254
Sequence Identity: 42% (87 aa)

VHKAVCIPRDEECAIKRINLEKCNTTMEELAKEIQAMCLCKHVNVVQYFTSFV--VKDEIWLVMRLLEAGSCLDLIKYMMKKGKGKGGLFEEAVIATILR
|.||...  ... ||| ..    |. ..|. |||  |  ||  ..|.|. |.      ..|.||   ..|| .|..|   .        . |. ||.||.
VYKAIHKQTGKIVAIKMVPV---NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRT-------LNEQQIACILY

ETLQGLDYLHENGQLHRDIKAGNILLGSDGTVQLADFGVSSWIATGGDLSR-DKVRTTFVGTPCWMAPEVMEQVTGYNFKADIWSFGILAIELATGAAPY
 |||||.||| |   |||||||||||  .|   |||||||      | |.     | |..|||.|||||| ... .|. |||||| || |||.| |  ||
DTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVS------GQLTDTMAKRNTVIGTPYWMAPEVIQEI-KYDCKADIWSLGITAIEMAEGMPPY

AKFPAM
. . .|
SDIHPM
Kinase FRAY.AA PAKA 4-209 40 4.9e-62 212.42 In-house 10-207 (260) Show / Hide 
Range on Protein: 4-209
Range on HMM: 10-207/260
Sequence Identity: 40% (86 aa)

GATATVHKAVCIPRDEE--CAIKRINLEKCNTTMEELAKEIQAMCLCKHVNVVQYFTSFVVKDEIWLVMRLLEAGSCLDLIKYMM--KKGKGKGGLFEEA
||. .| .|  |   .|  .|||..|... .  .| .  ||  |  ||| |.|.|  |..|.||.|.||  .|.|.  |.|. .   . .      ..|.
GASGEVYVATNIKTNQEENVAIKQMNMKNQP-KKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCN-----YMDEG

VIATILRETLQGLDYLHENGQLHRDIKAGNILLGSDGTVQLADFGVSSWIATGGDLSR-DKVRTTFVGTPCWMAPEVMEQVTGYNFKADIWSFGILAIEL
 || ..||.||||...|.... |||||  |||||.|| | ..|||     |    |.. .  |.| |||| ||||||  .   |. | |||| ||.|||.
QIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFG---FCA---QLTQEQQKRNTMVGTPYWMAPEVIRR-KQYDEKVDIWSLGIMAIEM

ATGAAPYAKFP
. |  || ..|
IEGEPPYLNEP
Kinase FRAY.AA S_TKc 3-250 27 3.9e-57 197.06 SMART 9-231 (231) Show / Hide 
Range on Protein: 3-250
Range on HMM: 9-231/231
Sequence Identity: 27% (72 aa)

HGATATVHKAVCIPRDEECAIKRINLEKCNTTMEELAKEIQAMCLCKHVNVVQYFTSFVVKDEIWLVMRLLEA--GSCLDLIKYMMKKGKGKGGLFEEAV
.|| ..|.|.. .  ....|||.|.        | . .||| .   .| |.|... .|.  |....|| ...   |. .|.|| . ..|...   | | .
KGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF--PFPE-H

IATILRETLQGLDYLHENGQLHRDIKAGNILLGSDGTVQLADFGVSSWIATGGDLSRDKVRTTFVGTPCWMAPEVMEQVTGYNF-KADIWSFGILAIELA
.. ........|.|.|..| .|||.|  |||| .  .. ..|||..  .            |||.||| .|||||.    ||.. |.|.||.|.. .|..
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

TGAAPYAKFPAMKESVLFLFRPTASKLLKSQFFKKPRNKPTASELLK-------SQFF
.|  |.     ..   . .  | |  ...  . | |.. ||| |.|.        ..|
CGYPPFP--QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase FRAY.AA KHS 9-199 44 2.1e-48 160.88 In-house 15-193 (258) Show / Hide 
Range on Protein: 9-199
Range on HMM: 15-193/258
Sequence Identity: 44% (86 aa)

VHKAVCIPRDEECAIKRINLEKCNTTMEELAKEIQAMCLCKHVNVVQYFTSFVVKDEIWLVMRLLEAGSCLDLIKYMMKKGKGKGGLFEEAVIATILRET
|.||  |  ||  |.| | .|  .  .. . .||  |  |.| |.| || |.. .| .|..|    .||  |.  | .       |  .|  || . |||
VYKARDIQSDELAAVKVIKME-PGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDI--YHVT------GPLSELQIAYVCRET

LQGLDYLHENGQLHRDIKAGNILLGSDGTVQLADFGVSSWIATGGDLSRDKVRTTFVGTPCWMAPEV--MEQVTGYNFKADIWSFGILAIELA
||||.||| .|..|||||  |||| ..| |.|||||||. |.    ...   |  |.||| ||||||  .|.  |||   |||. || |||||
LQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITAT--IAK---RKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELA
Kinase FRAY.AA Pkinase 4-205 29 1.1e-44 159.04 Pfam 10-212 (293) Show / Hide 
Range on Protein: 4-205
Range on HMM: 10-212/293
Sequence Identity: 29% (63 aa)

GATATVHKAVCIPRDEECAIKRINLEKCNTTMEELAK---EIQAMCLCKHVNVVQYFTSFVVKDEIWLVMRLLEAG----SCLDLIKYMMKKGKGKGGLF
|. ..| |.. .   .. |.|.|.... .  ... .    ||| |  ..| |.|... .|  ||.|..|| ..| |    .  |.|.        ..| |
GSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST------WRHGCF

--EEAVIATILRETLQGLDYLHENGQLHRDIKAGNILLGSDGTV----QLADFGVSSWIATGGDLSRDKVRTTFVGTPCWMAPEVMEQVTGYNFKADIWS
  .| ..  .....|.||.|.|..| .|||.|  |||. ..|..     ..|||..  .     . ..   |||.||| .|||||    ..|  |.|.||
YFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGILAIELATGAAPY
.|.. .|...|  |.
CGCILYEMLCGRPPF
Kinase FRAY.AA PAKL 22-212 39 2.9e-42 146.72 In-house 28-206 (256) Show / Hide 
Range on Protein: 22-212
Range on HMM: 28-206/256
Sequence Identity: 39% (77 aa)

AIKRINLEKCNTTMEELAKEIQAMCLCKHVNVVQYFTSFVVK-DEIWLVMRLLEAGSCLDLIKYMMKKGKGKGGLFEEAVIATILRETLQGLDYLHENGQ
||| | .   |   ... ||||    ||  |.| || |   | ...|  |    .||  |...   |        ..|. |. ||. || || |||  . 
AIKVIEIKESN-EIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCK-------TLNEKQISVILQQTLKGLHYLHSKNI

LHRDIKAGNILLGSDGTVQLADFGVSSWIATGGDLS-RDKVRTTFVGTPCWMAPEVMEQVTGYNFKADIWSFGILAIELATGAAPYAKFPAMK
 |||||| ||||  |. | .||||||. . .   ..   ..    .||| |||||.. . . || |.|||| || |||.| |  |    | |.
IHRDIKAANILLNEDCQVKIADFGVSQQLQD--EYDGQANQ---MIGTPYWMAPEIINK-QNYNNKCDIWSLGITAIEMADGFPPHYDMPPMR
Kinase FRAY.AA NinaC 47-206 42 5.3e-40 139.22 In-house 52-211 (267) Show / Hide 
Range on Protein: 47-206
Range on HMM: 52-211/267
Sequence Identity: 42% (71 aa)

LCKHVNVVQYFTSF-----VVKDEIWLVMRLLEAGSCLDLIKYMMKKGKGKGGLFEEAVIATILRETLQGLDYLHENGQLHRDIKAGNILLGSDGTVQLA
.| | |||...  .     .. |..|.|| .   ||  |..| ..| |.      .|..|| ||.|.. ||  ||.|  .|||.|  ||||  .| | | 
YCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCGR----RMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLC

DFGVSSWIATGGDLSRDKVRTTFVGTPCWMAPEV---MEQV-TGYNFKADIWSFGILAIELATGAAPYA
|||||  .      |    | | |||||||||||   |.|  . |   .|.|| || ||||. |  | |
DFGVSAQLD-----STRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGITAIELGDGDPPFA
Kinase FRAY.AA TKL 4-222 17 1.1e-39 138.11 In-house 4-318 (364) Show / Hide 
Range on Protein: 4-222
Range on HMM: 4-318/364
Sequence Identity: 17% (59 aa)

GATATVHKAVCIP--------RDEECAIKRINLEKCNT--------------------------TMEELAKEIQAMCLCKHVNVVQYFT------S--FV
|. ..|.|...          .... |.|... . ..                            .... .||  |  ..| |.||.        .  ..
GGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVC

VKD-----EIWLVMRLLEAGSCLDLIKYMMKKGKGKGGLFEEAVIATILRETLQGLDYLHENG--------QLHRDIKAGNILLGSDGT-----------
..      ....|| . . || |...                 ..  . ... .|..||| ..         .|||.|  |||. ...|           
MHPVGPWGQLCIVMEYCPGGSLLHYLH--------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---VQLADFGVSSWIATGGDLSRDK--------------VRTTFVGTPCWMAPEVMEQVT---------------GYNFKADIWSFGILAIELATGAAPY
   . ..||| | .. . |. .. .               . | .|||.||||||... .                |. |.|..||||.  |..|.  ||
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

AKFPAM------------KESVLFLFRPT
...| |            .  ..   ||.
YDYPYMPMIFQDPFEEMFMMVCDKGLRPP
Kinase FRAY.AA TyrKc 3-250 21 2.4e-14 9.13 SMART 9-280 (280) Show / Hide 
Range on Protein: 3-250
Range on HMM: 9-280/280
Sequence Identity: 21% (64 aa)

HGATATVHKAVCIPRDEECAIKRINLEKCNTTMEELAKEIQAMCLC--KHVNVVQYFTSFVVK-------DEIWLVMRLLEAGSCLDLIKYMMKKGKGKG
.||  .|.|.. .   ...|.| .. ..    .|.. .|.. ||    .| |.|. .   . .       . ...|| . . |...| ...  .|     
EGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-----

GLFEEAVIATILRETLQGLDYLHENGQLHRDIKAGNILLGSDGTVQLADFGVSSWIATGGDLSRDKVRT--------TFV-----GTP--C---WMAPEV
  .  .    .     .| .|||...  |||. | |.|.|...||  .|||          ||||            . .     |.       |||||.
--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFG----------LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

MEQVTG-YNFKADIWSFGILAIELAT-GAAPYAK----------FPAMKESVLFLFRPTA-------------SKLLKSQFFKKPRNKPTASELLKSQFF
.   .| ...| |.||||..  |. | |. ||              .  ..   . .|                .. |.    .| . || ||.   ..|
I--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase FRAY.AA Pkinase_Tyr 110-206 33 6.4e-14 47.77 Pfam 122-217 (270) Show / Hide 
Range on Protein: 110-206
Range on HMM: 122-217/270
Sequence Identity: 33% (33 aa)

QGLDYLHENGQLHRDIKAGNILLGSDGTVQLADFGVSSWIATGGDLS-RDKVRTTFVGTPCWMAPEVMEQVTGYNFKADIWSFGILAIELAT-GAAP-YA
.|..||....  |||. | |.|......|  .||| .  | .  |   | .  .       |||||..     .. | |.||||.|  |. | |. | |.
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGK--LPIKWMAPECINYGK-FTTKSDVWSFGVLMWEIFTYGEQPTYP
Kinase FRAY.AA YSK 233-250 50 2e-05 11.93 In-house 240-257 (257) Show / Hide 
Range on Protein: 233-250
Range on HMM: 240-257/257
Sequence Identity: 50% (9 aa)

KKPRNKPTASELLKSQFF
| |.. |.|.||||..| 
KDPEQRPSAKELLKHKFI
Kinase FRAY.AA STE20 233-250 55 0.000139 13.01 In-house 271-288 (288) Show / Hide 
Range on Protein: 233-250
Range on HMM: 271-288/288
Sequence Identity: 55% (10 aa)

KKPRNKPTASELLKSQFF
| | . ||||.||| .|.
KDPEKRPTASQLLKHPFI
Kinase FRAY.AA YSK 219-232 50 0.00028 8.39 In-house 244-257 (257) Show / Hide 
Range on Protein: 219-232
Range on HMM: 244-257/257
Sequence Identity: 50% (7 aa)

FRPTASKLLKSQFF
.||.|. |||..| 
QRPSAKELLKHKFI
Kinase FRAY.AA STE20 219-232 64 0.000403 11.3 In-house 275-288 (288) Show / Hide 
Range on Protein: 219-232
Range on HMM: 275-288/288
Sequence Identity: 64% (9 aa)

FRPTASKLLKSQFF
.|||||.||| .|.
KRPTASQLLKHPFI
Kinase FRAY.AA MST 233-250 38 0.006045 5.11 In-house 237-254 (254) Show / Hide 
Range on Protein: 233-250
Range on HMM: 237-254/254
Sequence Identity: 38% (7 aa)

KKPRNKPTASELLKSQFF
|.|   .|| .||.  |.
KNPEQRWTAEQLLQHPFI
Kinase FRAY.AA MST 220-232 46 0.014427 3.89 In-house 242-254 (254) Show / Hide 
Range on Protein: 220-232
Range on HMM: 242-254/254
Sequence Identity: 46% (6 aa)

RPTASKLLKSQFF
|.||  ||.  |.
RWTAEQLLQHPFI
Kinase FRAY.AA Pkinase_Tyr 8-56 19 0.019971 8.84 Pfam 14-69 (270) Show / Hide 
Range on Protein: 8-56
Range on HMM: 14-69/270
Sequence Identity: 19% (11 aa)

TVHKAVCI----PRDEECAIKRINLEKCNTT---MEELAKEIQAMCLC-KHVNVVQY
.|.|...       . ..|.| .  |..      .|.. .|.. |.   .| |.|..
EVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRL
Kinase FRAY.AA KHS 220-232 61 0.021236 3.73 In-house 246-258 (258) Show / Hide 
Range on Protein: 220-232
Range on HMM: 246-258/258
Sequence Identity: 61% (8 aa)

RPTASKLLKSQFF
||||.|||. .|.
RPTAEKLLQHPFV
Kinase FRAY.AA KHS 233-250 44 0.024301 3.53 In-house 241-258 (258) Show / Hide 
Range on Protein: 233-250
Range on HMM: 241-258/258
Sequence Identity: 44% (8 aa)

KKPRNKPTASELLKSQFF
| |. .|||. ||. .|.
KNPKKRPTAEKLLQHPFV
Kinase FRAY.AA PAKA 220-232 38 0.113519 1.83 In-house 248-260 (260) Show / Hide 
Range on Protein: 220-232
Range on HMM: 248-260/260
Sequence Identity: 38% (5 aa)

RPTASKLLKSQFF
|..|..||.  |.
RASAQELLHHPFL
Kinase FRAY.AA PAKA 235-250 31 0.261819 0.54 In-house 245-260 (260) Show / Hide 
Range on Protein: 235-250
Range on HMM: 245-260/260
Sequence Identity: 31% (5 aa)

PRNKPTASELLKSQFF
... ..|.|||.  |.
VDRRASAQELLHHPFL
Kinase FRAY.AA Pkinase 233-250 38 0.736448 4.12 Pfam 276-293 (293) Show / Hide 
Range on Protein: 233-250
Range on HMM: 276-293/293
Sequence Identity: 38% (7 aa)

KKPRNKPTASELLKSQFF
|.|   ||| ..|.. .|
KDPKKRPTAEQILQHPWF
Kinase FRAY.AA Pkinase 220-232 46 3.491658 1.73 Pfam 281-293 (293) Show / Hide 
Range on Protein: 220-232
Range on HMM: 281-293/293
Sequence Identity: 46% (6 aa)

RPTASKLLKSQFF
||||  .|.. .|
RPTAEQILQHPWF
FRWNK_Fray FRAY.AA FRWNK_Fray 368-463 61 5.1e-61 209.02 In-house 1-97 (97) Show / Hide 
Range on Protein: 368-463
Range on HMM: 1-97/97
Sequence Identity: 61% (60 aa)

TPPLSLILRLRNASKELHDIRFEFKAGQDTPNGLSQELVKEGLVDGRDVIVVAANLEKVVQN-RECKSMTFRLNSGCEVNEVPDDKALIGFAQLTVS
.||..|.||.||..|||.||||||. |.||..| .||||. |||||||...|||||.|...| ...||.||.|||||. |||||.||||||||....
QPPINLVLRMRNQKKELNDIRFEFTPGKDTAEGIAQELVSAGLVDGRDLVIVAANLQKLIDNPQTMKSVTFQLNSGCQPNEVPDEKALIGFAQISIH
OSR1_C FRAY.AA OSR1_C 371-402 34 2.3e-07 30.48 Pfam 1-38 (38) Show / Hide 
Range on Protein: 371-402
Range on HMM: 1-38/38
Sequence Identity: 34% (13 aa)

LSLILRLRNASK------ELHDIRFEFKAGQDTPNGLS
..| ||.|.. |      |...|.|||. ..||| . .
INLWLRMRDPKKRKGKHKENEAIQFEFDIEKDTPEEVA