Gene TAOK (Sea Urchin)

TAOK

Species: Sea Urchin
Alias: SPU_017927, Spk236, TAOK
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: TAO

Sequence

Name Sequence Type Origin Length Description Download
TAOK.AA Protein None 863 None Fasta, JSON
TAOK.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of TAOK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TAOK.AA TAO 28-281 76 1.7e-194 641.14 In-house 1-254 (254) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-254/254
Sequence Identity: 76% (194 aa)

FTGMTEIGHGSFGAVYHATNTITGEVVAIKKMLYNGKSSTEKWQDIIKEVRFIHRVRNANCIEFKGCYLREHTAWLAMEYCLGSASDVLDVHKKPLQEDE
|....|||||||||||.|....| |||||||| |.||.|.||||||||||||...|...||||.|||||||||.||.||||||||||.|||||||.||.|
FQDLREIGHGSFGAVYFARDKHTEEVVAIKKMSYSGKQSHEKWQDIIKEVRFLQQVKHPNCIEYKGCYLREHTCWLVMEYCLGSASDILDVHKKPMQEVE

IAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTVKLGDFGSASLVNPANSFVGTPFWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFN
|||.|.||||||.|||....|||||||.||||||||.|||.||||||.|.|||||||||.||||||||||||||||||||||||||||||||||||||||
IAAICHGALQGLRYLHSHKMIHRDIKAGNILLTEHGQVKLADFGSASMVCPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFN

MNAMSALYHIAQNDPPSLSTSGWNQCFHDFIKACLAKEPDSRPSARHLLQLEFV
||||||||||||||.|.|....|..|||.|...||.|.|..||||...|..|||
MNAMSALYHIAQNDSPTLQQNEWSDCFHQFVDKCLQKMPQERPSAEECLRHEFV
Kinase TAOK.AA STE20 28-281 43 4e-136 458.53 In-house 1-288 (288) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-288/288
Sequence Identity: 43% (125 aa)

FTGMTEIGHGSFGAVYHATNTITGEV----VAIKKMLYNGKSST-EKWQDIIKEVRFIHRVRNANCIEFKGCYLREHTA----WLAMEYCLG-SASDVLD
.. . .||.||.|.|| |... |||.    |||||| .. ..   ..|.||.||...  . .. | ... |.||...|.    |..|||| | |..|...
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---VHKK-----PLQEDEIAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTVKLGDFG-SASLVN--------PANSFVGTPFWMAPEVILAMD--
   ...|     |..|..||..| ..||||.|||.   |||||||.||||||.| ||| ||| .|.| .        . |.|||||.|||||||. |.  
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

EGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIA--QNDPPSLS---TSGWNQCFHDFIKACLAKEPDSRPSARHLLQLEFV
...|| |.|.||||||.||.||..||.|.|..|.|...|.  ||.|| |.   .. | ..||||.. || |.|. ||.| .||. .|.
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase TAOK.AA STE 28-281 31 1e-112 380.79 In-house 1-359 (359) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-359/359
Sequence Identity: 31% (116 aa)

FTGMTEIGHGSFGAVYHATNTI---------------TGEVVAIKKMLYNGKSS--------------TEKWQDIIKEVRFIHRVR--NANCIEFKGCYL
..|. .||.|.|| || | |                 |||..|||.| .. ...              .|..|.|.||... .. .    | ... |||.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

RE-------HTAWLAMEYCL-GSASDVLD---VHKKPLQ----------EDEIAAVCEGALQG-LEYLHNYETIHRDIKAANILLTEHGTVKLGDFGSAS
.|       .. |..|||.  ||..|...    ..|||.          |..||..|   |.| |.|||.   ||||||.|||||     ||| ||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

LVNP--------------------ANSFVGTPFWMAPEVILAMDEG---QYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN-----------
 ...                     |.||||| |||||||. ...|   .|| |.|.||||.|.||.|. |||...|. |.|...|..|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----DPPSLST------------------SGWNQCFHDFIKACLAKEPDSRPSARHLLQ--LEFV
    .||.| .                  . | ..|.|||. || |.|. ||.|  ||.   .|.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase TAOK.AA MST 28-281 41 2.5e-99 316.37 In-house 1-254 (254) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-254/254
Sequence Identity: 41% (110 aa)

FTGMTEIGHGSFGAVYHATNTITGEVVAIKKMLYNGKSSTEKWQDIIKEVRFIHRVRNANCIEFKGCYL--REHTAWLAMEYC-LGSASDVLDVHKKPLQ
|. .  .| ||.| || |..  ||..||||..  |     |  |.|||| ..     . .   . | |.   . . |. ||||  ||..|.    ...| 
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVN-----EDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLN

EDEIAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTVKLGDFG-SASLVN---PANSFVGTPFWMAPEVILAMDEGQYDGKVDVWSLGITCIELAE
|..||... ..||||.|||.   |||||||.|||| . |  || ||| |. | .    .|...|||.|||||||    |  || |.| ||||||.||.||
EQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVI---QEIKYDCKADIWSLGITAIEMAE

RKPPLFNMNAMSALYHIAQNDPPSLST-SGWNQCFHDFIKACLAKEPDSRPSARHLLQLEFV
 .||...  .|.|.  | |. ||...  . | | | ||.. ||.|.|. |..|  ||| .|.
GMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase TAOK.AA YSK 28-281 41 9.7e-94 282.6 In-house 1-257 (257) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-257/257
Sequence Identity: 41% (108 aa)

FTGMTEIGHGSFGAVYHATNTITGEVVAIKKMLYNGKSSTEKWQDIIKEVRFIHRVRNANCIEFKGCYLREHTAWLAMEYCL-GSASDVLDV-HKKPLQE
||    || |||| || . .  |..|||||    .  .. .   || .|. |       .   . | ||.    |  ||||  ||..| .   .  ...|
FTKQECIGRGSFGEVYKGIDNRTQRVVAIK--IIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDE

DEIAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTVKLGDFGSASLVN----PANSFVGTPFWMAPEVILAMDE-GQYDGKVDVWSLGITCIELAE
  || .    |.||.|||    |||||||||.||.||| |||.||| |. ..      | |||||.|||||||  . |  .|| |.|.|||||| .|.| 
KYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVI--CQEVSYYDFKADIWSLGITAYEMAK

RKPPLFNMNAMSALYHIAQNDPPSLSTSGWNQCFHDFIKACLAKEPDSRPSARHLLQLEFV
  ||.  . .| ..  |  | ||.|. . .   | .|. .|| |.|  ||||  ||  .|.
GEPPYCDYHPMRVMFLIPKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase TAOK.AA PAKA 28-281 39 5.3e-79 268.76 In-house 1-260 (260) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-260/260
Sequence Identity: 39% (106 aa)

FTGMTEIGHGSFGAVYHATNTITGEV--VAIKKMLYNGKSSTEKWQDIIKEVRFIHRVRNANCIEFKGCYLREHTAWLAMEYCL-GSASDVLDVHKK---
.. |..|| |. |.|| |||. |..   ||||.|  .  .. |.   || | .     .. | . .   || ..  |..|||   |.  ||..   .   
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKEL---IINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQC

-PLQEDEIAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTVKLGDFGSASLVNP----ANSFVGTPFWMAPEVILAMDEGQYDGKVDVWSLGITCI
 ...|. ||.||.  |||||..|.   ||||||  ||||   | ||. ||| .   ..     |. |||| |||||||.     ||| |||.||||| .|
NYMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRK---QYDEKVDIWSLGIMAI

ELAERKPPLFNMNAMSALYHIAQN-DPPSLSTSGWNQCFHDFIKACLAKEPDSRPSARHLLQLEFV
|..|  ||  |..   |.| ||.|  |. ...  | | |.|| ..|| ...|.|.||. ||. .| 
EMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase TAOK.AA S_TKc 28-281 27 2.5e-78 267.47 SMART 1-231 (231) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-231/231
Sequence Identity: 27% (73 aa)

FTGMTEIGHGSFGAVYHATNTITGEVVAIKKMLYNGKSSTEKWQDIIKEVRFIHRVRNANCIEFKGCYLREHTAWLAMEYCLG---SASDVLDVHKKP--
.. . .||.|.|| || .... ||..||||..           ..|..|..  .. .  | . .....   .  .. |||| |   .  |... ....  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LQEDEIAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTVKLGDFGSASLVNPANSFVGTPFWMAPEVILAMDEGQYDG-KVDVWSLGITCIEL
   . | ... ..   ...|||.|.   ||||.| .||||.|  ..|..|||.| ..   ..|.|||..|||||.      .|.. |.|.||.|.. .|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYEM

AERKPPLFNMNAMSALYHIAQNDPPSLSTSGWNQCFHDFIKACLAKEPDSRPSARHLLQ-------LEFV
. ..||      | .....              . . |||. || |.|. ||.|  .||        ...
LCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TAOK.AA KHS 28-281 41 2.2e-76 256.43 In-house 1-258 (258) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-258/258
Sequence Identity: 41% (109 aa)

FTGMTEIGHGSFGAVYHATNTITGEVVAIKKMLYNGKSSTEKWQDIIKEVRFIHRVRNANCIEFKGCYLREHTAWLAMEYC-LGSASDVLDVHKKPLQED
.  .  .| | .| || | .. ..|..|.| .  .     .  . | .|.  ..  | .| . . | |||.   |..||||  ||  |.  |   ||.| 
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKME---PGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVT-GPLSEL

EIAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTVKLGDFG-SASL---VNPANSFVGTPFWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERK
 || ||  .||||.|||. . .||||| ||||||..| ||| ||| || .   ..   ||.|||.||||||     .| |.   |.|..||| ||||| .
QIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQ

PPLFNMNAMSALYHIAQND--PPSLST-SGWNQCFHDFIKACLAKEPDSRPSARHLLQLEFV
||.|..  | ||. ... .  || |   . | | ||.|.| .| |.|  ||.| .||| .||
PPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase TAOK.AA SLK 28-281 37 4.6e-69 232.1 In-house 1-259 (259) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-259/259
Sequence Identity: 37% (99 aa)

FTGMTEIGHGSFGAVYHATNTITGEVVAIKKMLYNGKSSTEKWQDIIKEVRFIHRVRNANCIEFKGCYLREHTAWLAMEYCLGSASDVLDVH-KKPLQED
.  . |.| | || || | .    .|.|  ||.     . |. .| . |.  .  .   | ..  . |  ..  |. .|.| | | | . |  ..||.||
WEIIGELGDGAFGKVYKAQHK-EQKVFAAAKMIE--IKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTED

EIAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTVKLGDFG-SASLVNPAN---SFVGTPFWMAPEVIL--AMDEGQYDGKVDVWSLGITCIELAE
 |. ||.  ...|..||. . ||||.|| |||.|  | |.| ||| || . .. .   .|.|||.||||||..   . .  || |.|.|||||| ||.|.
QIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQ

RKPPLFNMNAMSALYHIAQNDPPSLST-SGWNQCFHDFIKACLAKEPDSRPSARHLLQLEFV
  ||  .|| |  |  |.. .|| | . | | . |.||.| || |.|. |... .|.| ..|
MEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase TAOK.AA Ste20-DD1 28-281 39 2.7e-68 233.16 In-house 1-268 (268) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-268/268
Sequence Identity: 39% (109 aa)

FTGMTEIGHGSFGAVYHA-------TNTITGEVVAIKKMLYNG-----KSSTEKWQDIIKEVRFIHRVRNANCIEFKGCYLREHTAWLAMEYCL-GSASD
|  .  || |||| |           ||   .|.|.| .  |.      |.  |  || |.      ..    ....|||..|      ||||  ||  |
FQIVEVIGQGSFGVVCTCRWMKKKDRNTNNNRVIACKFVEMNADDVEENSNLKKEIDILKNT-----MDCPYIVKYHGCYIKENMLMIVMEYCDGGSILD

VLDVHKKPLQEDEIAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTVKLGDFG-SASLV---NPANSFVGTPFWMAPEVILA--MDEGQYDGKVDV
...   | | |..|||.| .  .|| |||   ..|||||| |.|. . |  || ||| |. .|      |  .| |.||.||.|      .| || | |.
IMQMCSKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNTVIGSPYWMSPEIIMPPKGSQG-YDQKADI

WSLGITCIELAERKPPLFNMNAMSALYHIAQNDPPSLST-SGWNQCFHDFIKACLAKEPDSRPSARHLLQLEFV
|||||| ||.|| |||.||.|     . |    ||.|   | |   | |||| || ..|| ||||  ||   |.
WSLGITAIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI
Kinase TAOK.AA MSN 28-281 39 1.1e-67 222.53 In-house 1-265 (265) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-265/265
Sequence Identity: 39% (106 aa)

FTGMTEIGHGSFGAVYHATNTITGEVVAIKKMLYNGKSSTEKWQDIIKEVRFIHRVRN-ANCIEFKGCYLR------EHTAWLAMEYC-LGSASDVLDVH
|  .  .| | .| ||.   . ||...||| |  .     .  ..| .|. ....  .  | . . | ...      .|  |. ||.|  ||  |..   
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVRE----DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMT

K-KPLQEDEIAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTVKLGDFG-SASL---VNPANSFVGTPFWMAPEVILAMDE---GQYDGKVDVWSL
| . |.|| || .|   |.|| .||  . ||||||  |.|||.   ||| ||| || |   |   |.|.|||.||||||| | ||     || . |.||.
KGQSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVI-ACDENPDATYDYRSDLWSV

GITCIELAERKPPLFNMNAMSALYHIAQNDPPSLSTSGWNQCFHDFIKACLAKEPDSRPSARHLLQLEFV
||| ||.|| .||| .|  | ||. |  | || |  ..|.. ||.|.  || |.  .||.. ..|.  |.
GITAIEMAEGQPPLCDMHPMRALFLIPRNPPPKLKSKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase TAOK.AA Pkinase 28-281 28 1.2e-65 229.24 Pfam 1-293 (293) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

FTGMTEIGHGSFGAVYHATNTITGEVVAIKKMLYNGKSSTEKWQDIIK--EVRFIHRVRNANCIEFKGCYLREHTAWLAMEYCLGSASDVLDVH------
..    || |||| ||....  ||..||.|.. .  . . .|.|  ..  |..  .|..  | ....... ..   .. |||| |  . |.| .      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTW

-KKPL--QEDEIAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTV----KLGDFGSA----SLVNPANSFVGTPFWMAPEVILAMDEGQYDGKVDV
 ....  .|.|.  ..   |.||||.|.   ||||.| .|||. ..|..    |..|||.|       |....|.|||..||||||.  .   |. |||.
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIR--GGQYYGPKVDM

WSLGITCIELAERKPPLFNM----NAMSALYHIAQNDPPSLSTSGW----------------------NQCFHDFIKACLAKEPDSRPSARHLLQLEFV
||.|....|.. ..||  .     | .. .. |... .| |. . .                      .. . |||| ||.| | .||.|...|| ...
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase TAOK.AA Pkinase_Tyr 28-218 28 4.3e-21 72.06 Pfam 1-207 (270) Show / Hide 
Range on Protein: 28-218
Range on HMM: 1-207/270
Sequence Identity: 28% (60 aa)

FTGMTEIGHGSFGAVYHATNT----ITGEVVAIKKMLYNGKSSTE-KWQDIIKEVRFIHRV-RNANCIEFKGCYL-REHT--AWLAMEYC-LGSASDVLD
 | . ..|.|.|| ||..| .     |.  ||.|..  .| .. . ...| ..|..  .   .. | . . |. . ..     .. |||. .|.  | | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

VH---KKPLQEDEIAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTVKLGDFGSASLV-------NPANSFVGTPFWMAPEVILAMDEGQYDGKVD
 |   |.||   ..   |    .|.|||..   ||||. | |.|.|| ..|| .||| | ..         . .     .|||||.|  .    .  | |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK---FTTKSD

VWSLGITCIEL
||| |... |.
VWSFGVLMWEI
Kinase TAOK.AA TyrKc 28-281 23 7.2e-18 66.25 SMART 1-280 (280) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

FTGMTEIGHGSFGAVYHATNTITGEVVAIKKMLYNGKSSTEKWQDIIKEVRFIHRV--RNANCIEFKGCYLRE-------HTAWLAMEYC-LGSASDVLD
 |   ..|.| || ||..| .   . ||.|..  .        .|...| |  ...  .. | . . |. . .       .  .. |||. .|.  | | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

VHKKPLQEDEIAAVCEGALQGLEYLHNYETIHRDIKAANILLTEHGTVKLGDFGSASLVNPA-------NSFV-----GTP-----FWMAPEVILAMDEG
 |.. |. ..    |  . .| ||||    ||||. | |.|..| .||| .||| .  .             .     |.       |||||.|   ..|
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYG

QYDGKVDVWSLGITCIELAER-KPPLFN-----MNAMSALYHIAQNDPPSLSTSG-------WNQCFHDFIKACLAKEPDSRPSARHLLQLEFV
 .  | |||| |... |.  . ..|  .     |..  .. .. | . .    ..         .  .. .| | . .|..||. . .   |. 
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase TAOK.AA Pkinase_Tyr 255-280 23 5.522701 0.57 Pfam 246-270 (270) Show / Hide 
Range on Protein: 255-280
Range on HMM: 246-270/270
Sequence Identity: 23% (6 aa)

HDFIKACLAKEPDSRPSARHLLQLEF
.| .| | ...|. ||. . . . ..
YDLMKQCWHYDPEDRPTFSEI-HEQL