Gene Alk (Sea Urchin)
Alk
Sequence
Protein domains of Alk.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | Alk.AA | ALK | 2-236 | 71 | 3.6e-198 | 664.65 | In-house | 36-273 (273) | Show / Hide |
Range on Protein: 2-236 Range on HMM: 36-273/273 Sequence Identity: 71% (169 aa) TLPEHCTEQDELDFLMEALIMGNFDHPNVVSLLGICFKEKPLFIVLEYMEGGELKQFLRDIRPTEE--KPSSITMKDLLQITQDVAQGCRYLESRRFIHR |||| | .|||.||.|||||||.|.|.|||...||||...|..|||||||||..|.|||..||..| .||..|||||||...||||||.|||...|||| TLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPYMIVLEYMEGGDMKSFLRECRPHPESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHR DIAARNILLTTKESGRAAKIADFGMARDI-YRADYYRKGGQALLPVKWMPPEAFQDGIFTSKTDVWAYGVLLWEIISLGFMPYPGMSNQEVIQFVSAGER ||||||.|||.|..||.|||||||||||| ||||||||||.|..||||||||||.|||||||||||..|||.|||.|||.|||||..||||..||..|.| DIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRKGGRAMMPVKWMPPEAFMDGIFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGR MNPPRSCPQPVFNLMSQCWRHIPEDRPPFTTILESINY |.|||.|||||...|.|||.|.|||||.|.||||.| | MDPPRNCPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY |
|||||||||
| Kinase | Alk.AA | Pkinase_Tyr | 2-234 | 47 | 1.3e-126 | 429.41 | Pfam | 35-270 (270) | Show / Hide |
Range on Protein: 2-234 Range on HMM: 35-270/270 Sequence Identity: 47% (115 aa) TLPEHCTEQD--ELDFLMEALIMGNF-DHPNVVSLLGICF-KEKP--LFIVLEYMEGGELKQFLRDIRPTEEKPSSITMKDLLQITQDVAQGCRYLESRR .|.|...... ||. || || .. .|||.|.|.|.| ...| ..||.|||..| |. .||. | | . ..|||||||. ...|.|. ||||.. MLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR---EDKQPLTMKDLLQMCWQIAKGMEYLESKN FIHRDIAARNILLTTKESGRAAKIADFGMARDIYRADYY-RKGGQALLPVKWMPPEAFQDGIFTSKTDVWAYGVLLWEIISLGFMP-YPGMSNQEVIQFV .||||.||||.|.| .. .||.|||.||||| ||| ||.| . ||.|||.||....|.||.|.|||..|||.|||...| .| ||||||.||.... CIHRDLAARNCLVTE---NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI -SAGERMNPPRSCPQPVFNLMSQCWRHIPEDRPPFTTILESI |.|| .|. ||... .|| |||.. ||||| |. |.| . YEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
|||||||||
| Kinase | Alk.AA | TyrKc | 2-234 | 38 | 7.50000000001e-113 | 382.13 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 2-234
Range on HMM: 1-280/280
Sequence Identity: 38% (113 aa)
T---------------------------LPEHCTEQDELDFLMEALIMGNF--DHPNVVSLLGICFKE-------KPLFIVLEYMEGGELKQFLRDIRPT
| |.. . ||. || || .. .|||.| |.|.| .. .||.||.|||..| ||..||. ||.
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK
EEKPSSITMKDLLQITQDVAQGCRYLESRRFIHRDIAARNILLTTKESGRAAKIADFGMARDIYRA-------DYYRK----GGQALLPVKWMPPEAFQD
..|||||.. ..|.|..||.|...||||.||||.|.. . .||.|||..|||| ||||| || ..||..||.||....
------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY
GIFTSKTDVWAYGVLLWEIISLGFMPYPG-----MSNQEVIQFVSAGERMNPPRS--------CPQPVFNLMSQCWRHIPEDRPPFTTILESI
|.||.|.|||..||..||| ..| .|||| |||||||..| .|.|| .| . ||. ....|.|||.. ||||| |..| | .
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
|
|||||||||
| Kinase | Alk.AA | TK | 14-234 | 26 | 3.1e-105 | 353.82 | In-house | 84-486 (486) | Show / Hide |
Range on Protein: 14-234
Range on HMM: 84-486/486
Sequence Identity: 26% (107 aa)
DFLMEALIMGNFD-----HPNVVSLLGICFKE------------KPLFIVLEYMEGGE----LKQFLRDIRPTEEK------------------------
|||.||..| .. |||.|.|.|.|... .|. ||.|||..| |...||. ||.. .
DFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGD
-------------------------PSSITMKDLLQ-------------------ITQDVAQGCRYLESR------RFIHRDIAARNILLTTKES-----
|...|.||||| . ...|.|..||.|. .|.|||.||||.|.. .
ITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHF
---GRAAKIADFG--------MARDIYRADYYRKGG------------------------QALLPVKWMPPEAFQDGI---------FTSKTDVWAYGVL
|. .|||||| .|||||. |.|.. . .. ||..||.||...|.. ||.|.|||..|||
DGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVL
LWEIISLGFMPYPG-MSN---------QEVIQFVSAG--------------ERMNPPRSCP--------------QPVFNLMSQCWRHIPEDRPPFTTIL
.||| ..| .||.| ||| |||.... .| || .| || . .. || |||.. ||||| |....
MWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLH
ESI
| .
EQL
|
|||||||||
| Kinase | Alk.AA | Sev | 8-234 | 45 | 7e-103 | 343.63 | In-house | 43-277 (277) | Show / Hide |
Range on Protein: 8-234 Range on HMM: 43-277/277 Sequence Identity: 45% (108 aa) TEQDELDFLMEALIMGNFDHPNVVSLLGICFKEKPLFIVLEYMEGGELKQFLRDIRPTEEKPSS----ITMKDLLQITQDVAQGCRYLESRRFIHRDIAA | |. || || .|..| |||.| ..|.|. | .|..| |||| | .|| | | . .. .| ||. . |.. || ||| |.||| |. TDQEKQEFLKEAHLMSKFKHPNIVCQMGVCLDNEPQYIIMEHMEGGDLLCYLRAARMTTFQNPQPTAGLTLMDLVEMCIDISKGCEYLEDMHFVHRDLAC RNILLTTK--ES--GRAAKIADFGMARDIYRADYYRKGGQALLPVKWMPPEAFQDGIFTSKTDVWAYGVLLWEIISLGFMPYPGMSNQEVIQFVSAGERM || | ..| .. | || ||| ||||| ||||| | |||| || || ||.||. ||||.|.| |||..|| ||| || || .| || | RNCLVSVKDYTTHRRRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMAPESLMDGYFTTQSDVWAFGILCWEIMTLGHQPYPAHSNFEVLNHVQAGGRL NPPRSCPQPVFNLMSQCWRHIPEDRPPFTTILESI .|| || ....|.|||| |..|| | . . . QQPRMCPDDLWMMMRQCWRQDPWQRPSFHMCQNML |
|||||||||
| Kinase | Alk.AA | UTK | 4-234 | 39 | 1.9e-99 | 336.69 | In-house | 39-296 (296) | Show / Hide |
Range on Protein: 4-234 Range on HMM: 39-296/296 Sequence Identity: 39% (101 aa) PEHCTEQDEL---DFLMEAL---IMGNFD-HPNVVSLLGICFKEKPLFIVLEYMEGGELKQFLRDIRPTEE-KPSSITMKDLLQITQDVAQGCRYLESRR ... ..|.. ||..|| .|..|. ||||. |.|.|..|.|. ||.||||.| | ..||. ||| . | . |. ..|. |.| | ||.|.. HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCG FIHRDIAARNILLTTKE----SGRAAKIADFG---MARDIY---------RADYYRKGGQALLPVKWMPPEAFQDG-IFTSKTDVWAYGVLLWEIISLGF |.|||.||||.|.. . .. .|||||| |.|... ..||.. .| .|..|| |||. .. ||.|.|||..||..||| . | FVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGR MPYPGMSNQEVIQFVSAG--ERMNPPRSCPQPVFNLMSQCWRHIPEDRPPFTTILESI .|||||||..|...|..| ||..|..|| ||..|| .||. |..|| | .... . LPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM |
|||||||||
| Kinase | Alk.AA | InsR | 2-236 | 39 | 3.6e-91 | 306.48 | In-house | 38-278 (278) | Show / Hide |
Range on Protein: 2-236 Range on HMM: 38-278/278 Sequence Identity: 39% (97 aa) TLPEHCTEQDELDFLMEALIMGNFDHPNVVSLLGICFKEKPLFIVLEYMEGGELKQFLRDIRPTEE--KPSSI------TMKDLLQITQDVAQGCRYLES |. | . . ..||.|| .| .|.. .|| |||.| . | .| | |. | || .|| || || | . . ...| . ... | ||.. TVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRPEEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAA RRFIHRDIAARNILLTTKESGRAAKIADFGMARDIYRADYYRKGGQALLPVKWMPPEAFQDGIFTSKTDVWAYGVLLWEIISLGFMPYPGMSNQEVIQFV . |.||| |.|| . . ||.||||.|||| ||||||| .||| ||.|| ||.||.. ||| .||.|||. .|| || | || .| ... KKFVHRDLACRNCMVNHDF---TVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVFTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYI -SAGERMNPPRSCPQPVFNLMSQCWRHIPEDRPPFTTILESINY .| . || ||. .. || .||.. | .|| |. |.... GMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD |
|||||||||
| Kinase | Alk.AA | TK-Unique | 8-234 | 38 | 1.1e-87 | 297.68 | In-house | 43-294 (294) | Show / Hide |
Range on Protein: 8-234 Range on HMM: 43-294/294 Sequence Identity: 38% (97 aa) TEQDELDFLMEALIMGNFD-HPNVVSLLGICFKEK-PLFIVLEYMEGGELKQFLRDIRPT-----------------EEKPSS--ITMKDLLQITQDVAQ |..|. ||| |. .| . . |||.|..||.| | | .|..||...| | .|| ||. ..||. |..|||... ..|. TDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIAC GCRYLES--RRFIHRDIAARNILLTTKESGRAAKIADFGMARDIY-RADYYRKGGQALLPVKWMPPEAFQ--DGIF-TSKTDVWAYGVLLWEIISLGFMP | ||.| ....|||..|||.||| . .||.|||||||.| . .| ....| .|..||.||... .|.. |.|.|||..|||.||| .|| .| GMEYLASQRKKIVHRDLCARNVLLTE---DKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACP YPGMSNQEVIQFVSAGERMNPPRSC-PQPVFNLMSQCWRHIPEDRPPFTTILESI ||||.. .... . .| ||. | .| .. ..|||..||.. ||.|| |..|. . YPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL |
|||||||||
| Kinase | Alk.AA | Src | 14-234 | 40 | 4.5e-84 | 285.51 | In-house | 40-255 (255) | Show / Hide |
Range on Protein: 14-234 Range on HMM: 40-255/255 Sequence Identity: 40% (91 aa) DFLMEALIMGNFDHPNVVSLLGICFKEKPLFIVLEYMEGGELKQFLRDIRPTEEKPSSITMKDLLQITQDVAQGCRYLESRRFIHRDIAARNILLTTKES .|| || || ...|...|.|. .| .|.| .|| |||. | | ..|.. ... ... ...|. .. ||.| ||||...|||| ||||.| .. AFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK----DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENN- GRAAKIADFGMARDIYR--ADYYRKGGQALLPVKWMPPEAFQDGIFTSKTDVWAYGVLLWEIISLGFMPYPGMSNQEVIQFVSAGERMNPPRSCPQPVFN ..|.|||| || . | | | .|.||. |||.. | || |.||| .|.||.||.. | .|||||.|.||.| |..| || |. ||. ... --VCKVADFGLAR-LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYE -LMSQCWRHIPEDRPPFTTILESI .| |||. ||.|| | .. . QIMLQCWHKDPEQRPTFEYLQWFL |
|||||||||
| Kinase | Alk.AA | FGFR | 27-234 | 41 | 1.6e-80 | 273.83 | In-house | 64-293 (293) | Show / Hide |
Range on Protein: 27-234 Range on HMM: 64-293/293 Sequence Identity: 41% (96 aa) HPNVVSLLGICFKEKPLFIVLEYMEGGELKQFLRDIRPTE---EKPSS---------------------ITMKDLLQITQDVAQGCRYLESRRFIHRDIA |.|.. ||| | | ||... || . | |. ||| || . .| |. .| ||| ... ||.| ||.||. |||| | HKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRARRPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLA ARNILLTTKESGRAAKIADFGMARDIYRADYYRKGGQALLPVKWMPPEAFQDGIFTSKTDVWAYGVLLWEIISLGFMPYPGMS-NQEVIQFVSAGERMNP |||.| | . ||.||| |||| ||||| . ||.||| ||| .| ..|.. ||| |||||||| .| |||. | .. | || . ARNVLVT---DDYVMKICDFGLARDIHCIDYYRKTTNGRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEK PRSCPQPVFNLMSQCWRHIPEDRPPFTTILESI | |.| .. .| |||. |..||.|... |.. PHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL |
|||||||||
| Kinase | Alk.AA | Fer | 14-235 | 37 | 5.9e-77 | 261.59 | In-house | 54-283 (283) | Show / Hide |
Range on Protein: 14-235 Range on HMM: 54-283/283 Sequence Identity: 37% (88 aa) DFLMEALIMGN-FDHPNVVSLLGICFKEKPLFIVLEYMEGGELKQFLRDIRPTEEKPS-SITMKDLLQITQDVAQGCRYLESRRFIHRDIAARNILLTT- .|. || || | .|||||| . |.| | |. ||.|.. || |. .|. .... ........... ..|.| .||.|. |||||||||.|.. EFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYLK------KNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKD KESGRAAKIADFGMARD--IYRADYYRKGGQALLPVKWMPPEAFQDGIFTSKTDVWAYGVLLWEIISLGFMPYPG----MSNQEV----IQF-VSAGERM | ||.||||.|. | ||. | . .|..|..||..|.||...|||||..||..||| . | |||| | . .| .. . .| .| KVKKK-CKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMM NPPRSCPQPVFNLMS-QCWRHIPEDRPPFTTILESIN .| ..| .. ..| ||| . ||||| ...| . .. PMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK |
|||||||||
| Kinase | Alk.AA | Tec | 12-236 | 43 | 4.5e-72 | 245.75 | In-house | 38-254 (254) | Show / Hide |
Range on Protein: 12-236 Range on HMM: 38-254/254 Sequence Identity: 43% (97 aa) ELDFLMEALIMGNFDHPNVVSLLGICFKEKPLFIVLEYMEGGELKQFLRDIRPTEEKPSSITMKDLLQITQDVAQGCRYLESRRFIHRDIAARNILLTTK | ||. || .| . ||. | | |.| ...|..|| |||| | | .|| . . .| .| ||...||| .| |||. ||||| |||| | EEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAI----LLEMCQDVCEGMAYLERHCFIHRDLAARNCLV--- ESGRAAKIADFGMARDIYRADYYRKGGQALLPVKWMPPEAFQDGIFTSKTDVWAYGVLLWEIISLGFMPYPGMSNQEVIQFVSAGERMNPPRSCPQPVFN .. |..||||.| . .| .| . |||| ||| |. . || ||||.||| ||. |.| |||. ||| ||.. || | |. |..|.. .. GDQCVVKVSDFGMTRYVLDDQYTSSVG-TKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQ LMSQCWRHIPEDRPPFTTILESINY | .||.. ||.||.| |..| IMYHCWHEKPEERPTFQQLLRQITE |
|||||||||
| Kinase | Alk.AA | Pkinase | 9-234 | 20 | 1.6e-25 | 91.28 | Pfam | 40-293 (293) | Show / Hide |
Range on Protein: 9-234 Range on HMM: 40-293/293 Sequence Identity: 20% (55 aa) EQDELDFL-MEALIMGNFDHPNVVSLLGICFKEKPLFIVLEYMEGG----ELKQFLRDIRPTEEKPSSI--TMKDLLQITQDVAQGCRYLESRRFIHRDI ..|. ... .|. || ...|||.| |.... .. . .|.||.||| .|. ... .. .. ..... . ...| |. |...||||. WKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-----WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDL AARNILLTTKESGRAA---KIADFGMARDIYRADYYRKGGQALLPV---KWMPPEAFQ-DGIFTSKTDVWAYGVLLWEIISLGFMPYPGM----SNQEVI |||. . | . ||.||| |. .. | ... . .. .|.|| . . ..| |.|..|..|.| .. | |.|| . . . KPENILID--NNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQM QFVSAGERMNPPRSCP-----------------------QPVFNLMSQCWRHIPEDRPPFTTILES--I | . . .....| .. ... |.. |..|| .. ||.. . QMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
|||||||||
| Kinase | Alk.AA | S_TKc | 5-236 | 20 | 1.5e-20 | 75.5 | SMART | 19-231 (231) | Show / Hide |
Range on Protein: 5-236
Range on HMM: 19-231/231
Sequence Identity: 20% (52 aa)
EHCT--------EQDELDFLMEALIMGNFDHPNVVSLLGICFKEKPLFIVLEYMEG--GELKQFLRDIRPTEEKPSSITMKDLLQITQDVAQGCRYLESR
| . . ... | |. . .|||.| |.... . |..|.||..| |.|...... |... ... .. . ... .... |. |.
RHKKTGRIVAIKIIK-EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKK-RGRHGLRFPFPE-HARFYMYQICCALEYCHSH
RFIHRDIAARNILLTTKESGRAAKIADFGMARDIYRADYYRKGGQALLPVKWMPPEAFQDGIFTS-KTDVWAYGVLLWEIISLGFMPYPGMSNQEVIQFV
..||||. ||||.. ||.|||.|| . .|.|| . .. | |.|. |..|.| .. | |.| |.... .
GIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKI
SAGERMNPPRSCPQPVFNLMSQCWRHIPEDRPPFTTILE-------SINY
.... .....|.. ||.|| .|.
G-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
|||||||||
| Kinase | Alk.AA | ALK | 548-568 | 71 | 2.3e-12 | 38.99 | In-house | 253-273 (273) | Show / Hide |
Range on Protein: 548-568 Range on HMM: 253-273/273 Sequence Identity: 71% (15 aa) CWRHIPEDRPPFTTILESINY ||.|.|||||.|.||||.| | CWQHQPEDRPKFVTILEHIQY |
|||||||||
| Kinase | Alk.AA | FGFR | 548-566 | 36 | 2e-06 | 17.97 | In-house | 275-293 (293) | Show / Hide |
Range on Protein: 548-566 Range on HMM: 275-293/293 Sequence Identity: 36% (7 aa) CWRHIPEDRPPFTTILESI ||. |..||.|... |.. CWHFKPCQRPTFKQLVEYL |
|||||||||
| Kinase | Alk.AA | Tec | 548-568 | 42 | 5e-06 | 17.15 | In-house | 234-254 (254) | Show / Hide |
Range on Protein: 548-568 Range on HMM: 234-254/254 Sequence Identity: 42% (9 aa) CWRHIPEDRPPFTTILESINY ||.. ||.||.| |..| CWHEKPEERPTFQQLLRQITE |
|||||||||
| Kinase | Alk.AA | TK | 548-566 | 47 | 5e-06 | 15.26 | In-house | 468-486 (486) | Show / Hide |
Range on Protein: 548-566 Range on HMM: 468-486/486 Sequence Identity: 47% (9 aa) CWRHIPEDRPPFTTILESI ||.. ||||| |....| . CWHYDPEDRPTFSQLHEQL |
|||||||||
| Pkinase_Tyr | Alk.AA | Pkinase_Tyr | 547-566 | 50 | 3.8e-05 | 18.05 | Pfam | 251-270 (270) | Show / Hide |
Range on Protein: 547-566 Range on HMM: 251-270/270 Sequence Identity: 50% (10 aa) LCWRHIPEDRPPFTTILESI .||.. ||||| |. |.| . QCWHYDPEDRPTFSEIHEQL |
|||||||||
| Kinase | Alk.AA | Sev | 547-566 | 35 | 0.000123 | 11.18 | In-house | 258-277 (277) | Show / Hide |
Range on Protein: 547-566 Range on HMM: 258-277/277 Sequence Identity: 35% (7 aa) LCWRHIPEDRPPFTTILESI .||| |..|| | . . . QCWRQDPWQRPSFHMCQNML |
|||||||||
| Kinase | Alk.AA | InsR | 548-568 | 33 | 0.000197 | 10.69 | In-house | 258-278 (278) | Show / Hide |
Range on Protein: 548-568 Range on HMM: 258-278/278 Sequence Identity: 33% (7 aa) CWRHIPEDRPPFTTILESINY ||.. | .|| |. |.... CWQYQPKMRPTFLDIIHYLCD |
|||||||||
| Kinase | Alk.AA | TK-Unique | 548-566 | 42 | 0.000236 | 11.06 | In-house | 276-294 (294) | Show / Hide |
Range on Protein: 548-566 Range on HMM: 276-294/294 Sequence Identity: 42% (8 aa) CWRHIPEDRPPFTTILESI ||.. ||.|| |..|. . CWQWEPEERPSFRQIKHRL |
|||||||||
| Kinase | Alk.AA | Fer | 548-567 | 40 | 0.000896 | 8.86 | In-house | 264-283 (283) | Show / Hide |
Range on Protein: 548-567 Range on HMM: 264-283/283 Sequence Identity: 40% (8 aa) CWRHIPEDRPPFTTILESIN || . ||||| ...| . .. CWQKDPEDRPTMKEICQKLK |
|||||||||
| Kinase | Alk.AA | Src | 548-566 | 36 | 0.003861 | 6.46 | In-house | 237-255 (255) | Show / Hide |
Range on Protein: 548-566 Range on HMM: 237-255/255 Sequence Identity: 36% (7 aa) CWRHIPEDRPPFTTILESI ||. ||.|| | .. . CWHKDPEQRPTFEYLQWFL |
|||||||||
| Kinase | Alk.AA | UTK | 548-566 | 31 | 0.010057 | 5.15 | In-house | 278-296 (296) | Show / Hide |
Range on Protein: 548-566 Range on HMM: 278-296/296 Sequence Identity: 31% (6 aa) CWRHIPEDRPPFTTILESI ||. |..|| | .... . CWHYDPQERPDFEDLVQQM |
|||||||||