Gene Fer (Sea Urchin)

Fer

Species: Sea Urchin
Alias: SPU_025086, Fer, Spk263
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
Fer.AA Protein None 487 None Fasta, JSON
Fer.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of Fer.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 Fer.AA SH2 34-114 34 1.8e-21 78.57 SMART 1-87 (87) Show / Hide 
Range on Protein: 34-114
Range on HMM: 1-87/87
Sequence Identity: 34% (30 aa)

EEFYHGALPRKETEALLVN----DGDFVVREKSDAWGRYVLSAKHASKVRHFPIQINDENMYRLEG---DAFQTVGELIRFQLNSRQP
...||| ..|.| |.|| |    ||||.||. .   | |||| .. .||.|. |. ||...|....     |... ||...    ...
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 Fer.AA SH2 36-108 34 4.6e-21 63.66 Pfam 1-81 (81) Show / Hide 
Range on Protein: 36-108
Range on HMM: 1-81/81
Sequence Identity: 34% (28 aa)

FYHGALPRKETEALLVN----DGDFVVREKSDAWGRYVLSAKHAS---KVRHFPIQINDEN-MYRLEGDAFQTVGELIRFQ
.||| ..|.| | || |    ||.|.||| .   | |.|| .. .   .|.|. || .|.   |. ... |... ||. . 
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
Kinase Fer.AA Fer 141-394 43 4.7e-146 491.51 In-house 1-283 (283) Show / Hide 
Range on Protein: 141-394
Range on HMM: 1-283/283
Sequence Identity: 43% (122 aa)

IDLEEKLGAGHFGDVHRGR-----IKR-----TQLAVAVKTCKET-VDAATRRKFLQEANILKQ-YDHANIVKLIGVCTDKHPIYIVMELVPGGDLLSFL
..|..||| |.||.|..||     .|      ...||.||.||.. .... ...|..||.|... ||| |.||..|||.|..||.||||...||.|.|.|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

RTDQNE-LSTKQRVKMGEDAASGMAYLESKQCIHRDLAARNCLVGN-KNVIK--ISDFGMSRE--DDVYTIREG-AMRQIPIKWTAPEAMNFGKYTSMSD
.. .|. .|......|  .||.||.||.||.|||||.||||||... |...|  ||||||||.  |..|. ... .....||.|.|||....| |....|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWSFGILLWEIFSNGSTPYPG------MTNN--EAREKVQQ-GYRMPPPEITPEEVRILMD-NCWKMVDEDRPRFKDAQTTLK
|||||...||||.|| .||||      |||   .||..... ||.||.|. .|.|.. .|. .||.. .|||| .|... .||
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase Fer.AA Pkinase_Tyr 141-393 49 1.9e-136 462.77 Pfam 1-270 (270) Show / Hide 
Range on Protein: 141-393
Range on HMM: 1-270/270
Sequence Identity: 49% (135 aa)

IDLEEKLGAGHFGDVHRGRIK----RTQLAVAVKTCKETVDAAT--RRKFLQEANILKQY-DHANIVKLIGVCT-DKHP--IYIVMELVPGGDLLSFLRT
| . .|||.|.||.|..|. |     |.. ||||..||. .     |..|..||.|.||. .| |||.|.|||| .. |  ||||||..|.||||..||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

D---QNELSTKQRVKMGEDAASGMAYLESKQCIHRDLAARNCLVGNKNVIKISDFGMSR---EDDVY-TIREGAMRQIPIKWTAPEAMNFGKYTSMSDVW
    .. |..|. ..|  . |.||.|||||.|||||||||||||...||.||.|||..|   .|| | . |.|..  .||||.|||..|.||.|. ||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK--LPIKWMAPECINYGKFTTKSDVW

SFGILLWEIFSNGSTP-YPGMTNNEAREKV-QQGYRMPPPEITPEEVRILMDNCWKMVDEDRPRFKDAQTTL
|||.|.||||. | .| ||||.|.|  |.. ..|||||.|| .|.|.  ||  ||.   ||||.|.. .  |
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Fer.AA TyrKc 141-393 42 1.4e-133 450.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 141-393
Range on HMM: 1-280/280
Sequence Identity: 42% (122 aa)

IDLEEKLGAGHFGDVHRGRIKRTQLAVAVKTCKETVDAATRRKFLQEANILKQY--DHANIVKLIGVCTDK-------HPIYIVMELVPGGDLLSFLRTD
| |..||| |.|| |..|. |   . ||||..||      |. |..||.|....  .| |||.|.||||..       .|..||||..|.|||...||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

QNELSTKQRVKMGEDAASGMAYLESKQCIHRDLAARNCLVGNKNVIKISDFGMSREDDVY--------TIREGA--MRQ--IPIKWTAPEAMNFGKYTSM
...|..|. ...  ..|.||.||.||.||||||||||||||.....||||||.||. . .        ..|      .   .||.|.|||..|.||.|. 
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

SDVWSFGILLWEIFSNGSTPYPG-----MTNNEAREKVQQGYRMPPPEI--------TPEEVRILMDNCWKMVDEDRPRFKDAQTTL
|||||||...||||..| .||||     |.| |..|.|.||||||.|.          |.|.  .|  ||.   ||||.|..    .
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Fer.AA TK 141-393 25 1.1e-119 403.11 In-house 1-486 (486) Show / Hide 
Range on Protein: 141-393
Range on HMM: 1-486/486
Sequence Identity: 25% (123 aa)

IDLEEKLGAGHFG---DVHRGRIKRTQ-------------------------LAVAVKTCKETVDAATRR-------------KFLQEANILKQYD----
| |..|||.|.||   .|..|. ..                             ||||..||. ... ..             .||.||...|. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HANIVKLIGVCTDK------------HPIYIVMELVPGGD----LLSFLRTDQNE--------------------------------------------
 | |||.|.||||..            .|..||||..|.||    |...||.  ..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSTKQRVKMGEDAASGMAYLESK------QCIHRDLAARNCLVGNKNV-----------IKISDFGMSR
                               |...|.. |  ..|.||.||.||      ...||||||||||||..||           .||.|||.||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----------EDDVYTIREGAMR----------------------QIPIKWTAPEAMN---------FGKYTSMSDVWSFGILLWEIFSNGSTPYPG-M
           .|| |. ...  .                      ..||.|.|||..|         .||.|. |||||||.|.||||..| .||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TN---------NEAREKVQQG--------------YRMPPPEITP--------------EEVRILMDNCWKMVDEDRPRFKDAQTTL
.|          |  |....|              .|||.|.  |              ||. .||  ||.   ||||.|.. .  |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Fer.AA SFK-Src 141-397 48 3.5e-112 333.86 In-house 1-259 (259) Show / Hide 
Range on Protein: 141-397
Range on HMM: 1-259/259
Sequence Identity: 48% (129 aa)

IDLEEKLGAGHFGDVHRGRIKRTQLAVAVKTCKETVDAATRRKFLQEANILKQYDHANIVKLIGVCTDKHPIYIVMELVPGGDLLSFLRT-DQNELSTKQ
| ||.|||.| |||| .||   |  .||||| |    |     ||||| ..|.  | | ..|  ||||. ||||. ||.  | || .|.      |   |
IRLEKKLGSGQFGDVWKGRWNNT-TEVAVKTLKPG--AMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQ

RVKMGEDAASGMAYLESKQCIHRDLAARNCLVGNKNVIKISDFGMSR---EDDV-YTIREGAMRQIPIKWTAPEAMNFGKYTSMSDVWSFGILLWEIFSN
 | |. . |.|||||| .  .|||||||| |||. ||.|. ||||||   .||  || .|||    |||||||||||  ..   |||||||||. ||   
LVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGA--KFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTY

GSTPYPGMTNNEAREKVQQ--GYRMPPPEITPEEVRILMDNCWKMVDEDRPRFKDAQTTLKRAY
|  ||||||| |   .| .  ||||| |  .|.|   .| .||.   .||| |   .  .   .
GRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase Fer.AA Src 141-393 48 1.3e-109 370.49 In-house 1-255 (255) Show / Hide 
Range on Protein: 141-393
Range on HMM: 1-255/255
Sequence Identity: 48% (125 aa)

IDLEEKLGAGHFGDVHRGRIKRTQLAVAVKTCKETVDAATRRKFLQEANILKQYDHANIVKLIGVCTDKHPIYIVMELVPGGDLLSFLR--TDQNELSTK
| |..|||.|.||.|  |  . .   ||||| |.         |||||.|.|. .| ..|.|  ||... ||||| |.   | || .|.  ..  .|. .
IKLCRKLGQGQFGEVWMGYWNGN-TKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLP

QRVKMGEDAASGMAYLESKQCIHRDLAARNCLVGNKNVIKISDFGMSR--E--DDVYTIREGAMRQIPIKWTAPEAMNFGKYTSMSDVWSFGILLWEIFS
| . |.   |.|||||||.. ||||||||| |||..|| |. |||  |  .  ||.|. |.||.  .||||||||| |.|..|  ||||||||||.||..
QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAK--FPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVT

NGSTPYPGMTNNEAREKVQQGYRMPPPEITPEEVRI-LMDNCWKMVDEDRPRFKDAQTTL
 | .||||||| |. ..|..||||| |.  |.|.   .|  ||.   |.|| |.  |  |
YGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Fer.AA UTK 141-393 37 3e-100 339.35 In-house 1-296 (296) Show / Hide 
Range on Protein: 141-393
Range on HMM: 1-296/296
Sequence Identity: 37% (110 aa)

IDLEEKLGAGHFGDVHRGRIKR-----TQLAVAVKTCK-ETVDAATRR---KFLQEAN---ILKQYD-HANIVKLIGVCTDKHPIYIVMELVPGGDLLSF
. | ..||.|.||.||..| ..     ....||||.|. . ..  ...   .|. ||.   ..|| . | |...|.||||.  |..||.|. ..|||.|.
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRTDQNE-------LSTKQRVKMGEDAASGMAYLESKQCIHRDLAARNCLVGNK-------NVIKISDFG---MSREDD----------VYTIREGAMRQ
||.   .       |.  ||..|  | |.||.||.|....|||||||||||.         .|.||.|||   |||.             |  .    ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

IPIKWTAPEAMNFG-KYTSMSDVWSFGILLWEIFSNGSTPYPGMTNNEAREKVQQG--YRMPPPEITPEEVRILMDNCWKMVDEDRPRFKDAQTTL
.||.|.||||.. . ..|. |||||||...|||...|..|||||.| .. . |  |  ||||.|.  |..|  ||  ||..  ..||.|.|   ..
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase Fer.AA Abl 141-393 46 1e-95 319.81 In-house 1-252 (252) Show / Hide 
Range on Protein: 141-393
Range on HMM: 1-252/252
Sequence Identity: 46% (120 aa)

IDLEEKLGAGHFGDVHRGRIKRTQLAVAVKTCKETVDAATRRKFLQEANILKQYDHANIVKLIGVCTDKHPIYIVMELVPGGDLLSFLR-TDQNELSTKQ
| ...||| | .|.|  |  || .. ||||| ||  |.     ||.|| |.|.  | |.|.|.||||   | ||. | .. | || .|| .|..||.   
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKE--DTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVV

RVKMGEDAASGMAYLESKQCIHRDLAARNCLVGNKNVIKISDFGMSR--EDDVYTIREGAMRQIPIKWTAPEAMNFGKYTSMSDVWSFGILLWEIFSNGS
 . |    |||| |||... |||||||||||||.....|. |||..|  .||.|| . ||  . ||||||||.. . |. | |||| ||.|||||   | 
LLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGA--KFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGM

TPYPGMTNNEAREKVQQGYRMPPPEITPEEVRILMDNCWKMVDEDRPRFKDAQTTL
.||||.  ..  .|...||||  ||  |..|  || .||.    |||.||.   ..
SPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase Fer.AA Tec 141-395 40 5.5e-91 308.57 In-house 1-254 (254) Show / Hide 
Range on Protein: 141-395
Range on HMM: 1-254/254
Sequence Identity: 40% (105 aa)

IDLEEKLGAGHFGDVHRGRIKRTQLAVAVKTCKETVDAATRRKFLQEANILKQYDHANIVKLIGVCTDKHPIYIVMELVPGGDLLSFLRTDQNELSTKQ-
. . . || | || ||.|. .  |  ||.|. ||   .     |..|| . .   | . |.| |||. . ||||| | .  | ||..||. . ...... 
LTFMKELGSGQFGVVHLGKWRH-QYDVAIKMIKEG--SMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMA

-RVKMGEDAASGMAYLESKQCIHRDLAARNCLVGNKNVIKISDFGMSR--EDDVYTIREGAMRQIPIKWTAPEAMNFGKYTSMSDVWSFGILLWEIFSNG
   .|  |   ||||||... ||||||||||||| ..|.|.|||||.|   || ||   |.    |.|| .|| ... .| | ||||.||.| ||.|| |
ILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGT--KFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCG

STPYPGMTNNEAREKVQQGYRMPPPEITPEEVRILMDNCWKMVDEDRPRFKDAQTTLKR
  ||. |.| |  |.|.||.|.  |.  ....   |  ||.   |.|| |..   ... 
KMPYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase Fer.AA Eph 141-393 43 1.3e-90 304.66 In-house 1-264 (264) Show / Hide 
Range on Protein: 141-393
Range on HMM: 1-264/264
Sequence Identity: 43% (116 aa)

IDLEEKLGAGHFGDVHRGRIK----RTQL---AVAVKTCKETVDAATRRKFLQEANILKQYDHANIVKLIGVCTDKHPIYIVMELVPGGDLLSFLRTDQN
| .|. .||| ||.| .||.|    ....   .||.|| |..  .  |. || || |. |.|| ||..| || |   |. || |    | | ||||.   
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHDG

ELSTKQRVKMGEDAASGMAYLESKQCIHRDLAARNCLVGNKNVIKISDFGMSRE-------DDVYTIREGAMRQIPIKWTAPEAMNFGKYTSMSDVWSFG
.... | | |    |||| || .   .|||||||| ||  . | |.||||.||.       ...|| | |    |||.||||||. ..|.|| |||||.|
QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGG---KIPIRWTAPEAIAYRKFTSASDVWSYG

ILLWEIFSNGSTPYPGMTNNEAREKVQQGYRMPPPEITPEEVRILMDNCWKMVDEDRPRFKDAQTTL
|..||. | |  ||  |.| .  . ..|||| |||   ||    || .||..  ..||.|.. . .|
IVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase Fer.AA TK-Unique 141-393 35 4.4e-88 298.95 In-house 1-294 (294) Show / Hide 
Range on Protein: 141-393
Range on HMM: 1-294/294
Sequence Identity: 35% (104 aa)

IDLEEKLGAGHFGDVHRGRIKRTQ------LAVAVKTCKETVDAATRRKFLQEANILKQYD-HANIVKLIGVCTDKH-PIYIVMELVPGGDLLSFLRTDQ
. .....| | || |.|| ....         ||||..|. ..  ....||.|....|. . | |||...|.||..  | .|.|| .|.|.|...||| .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

NE-------------------------LSTKQRVKMGEDAASGMAYLES--KQCIHRDLAARNCLVGNKNVIKISDFGMSR--EDDVYTIREGAMRQIPI
 .                         .| |. .  . . |.||.||.|  |...||||.|||.|.....|.||.||||.|  ...  .....    |||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWTAPEAMN--FGKY-TSMSDVWSFGILLWEIFSNGSTPYPGMTNNEAREKVQQGYRMPPPEIT-PEEVRILMDNCWKMVDEDRPRFKDAQTTL
.| |||..    | | |. |||||||.|.||||..|..||||| . . .|....||||| ||   ..|.. || .||. . |.|| | .    |
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase Fer.AA Src-Unclassified 141-386 41 1.7e-86 293.64 In-house 1-277 (284) Show / Hide 
Range on Protein: 141-386
Range on HMM: 1-277/284
Sequence Identity: 41% (115 aa)

IDLEEKLGAGHFGDVHRGRIKRTQLAVAVKTCKET-VDAATRRKFL--------QEANILKQYDHANIVKLIGVCTDKHPIYIVMELVPGGDLLSFLRTD
. |  ||| | || |  | . |    ||||| ..   .      ||        |||.|.|. .| |.|.| .||..  |.||. |.   | || .||..
VHLLRKLGRGQFGEVWYG-KWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREG

Q-NELSTKQR------------VKMGEDAASGMAYLESKQCIHRDLAARNCLVGNKN-----VIKISDFGMSR----EDDVYTIREGAMRQIPIKWTAPE
    |  .              | .    |||| |||||. .|||||||| |.| .|     | |. |||  |    .|| |  | |||   |.||.|||
GGQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAM--FPWKWMAPE

AMNFGKYTSMSDVWSFGILLWEIFSNGSTPYPGMTNNEAREKVQQGYRMPPP--EITPEEVRI-LMDNCWKMVDEDRPRF
.   |. .  |||||.|||||||.  | |||||| | |. | |  ||||| |  .  |. .   .|  ||  . . || |
CFIYGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTF
Kinase Fer.AA S_TKc 141-398 25 2.4e-54 187.81 SMART 1-231 (231) Show / Hide 
Range on Protein: 141-398
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

IDLEEKLGAGHFGDVHRGRIKRTQLAVAVKTCKETVDAATRRKFLQEANILKQYDHANIVKLIGVCTDKHPIYIVMELVPG--GDLLSFLRTDQNE----
 .. .|.| | || |...| |.|.  ||.|  |        .....| .|||. .| |||||..|. | . .|.|||...|  |||.....  . .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSTKQRVKMGEDAASGMAYLESKQCIHRDLAARNCLVGNKNVIKISDFGMSREDDVYTIREGAMRQIPIKWTAPEAMNFGKYTS-MSDVWSFGILLWEI
 ..  .  ..    .....|. |.. |||||   | |. .  .|||.|||..|.                 . ||| .   .|.   .|.||.|..|.| 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

FSNGSTPYPGMTNNEAREKVQQGYRMPPPEITPEEVRILMDNCWKMVDEDRPRFKDAQT----TLKRAYK
.. | .|.|  . ..  .|.            ..|.. ....|...  |.||   .| .      .  . 
LC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Fer.AA Pkinase 141-393 23 2e-40 144.0 Pfam 1-293 (293) Show / Hide 
Range on Protein: 141-393
Range on HMM: 1-293/293
Sequence Identity: 23% (71 aa)

IDLEEKLGAGHFGDVHRGRIKRTQLAVAVKTCKETVDAA--TRRKFL-QEANILKQYDHANIVKLIGVCTDKHPIYIVMELVPGG----DLLSFLR-TDQ
. ...|.|.| || | ... | |.  ||||. |   .     ..... .|. |.|  .| |||.|.....||  ||.|||...||    || ....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NEL--STKQRVKMGEDAASGMAYLESKQCIHRDLAARNCLVGNKNVI----KISDFGMSRE--DDVYTIREGAMRQIPIKWTAPEAMN-FGKYTSMSDVW
. .  | ..  ..    ..|..|. |. .|||||   |.|. |...|    ||.||| ..      ..      .   . . |||  .   .|.. .|.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MT--TFCGTPWYMAPEVIRGGQYYGPKVDMW

SFGILLWEIFSNGSTPYPGM----TNNEAREKVQQGYRMPPPEITP-----------------------EEVRILMDNCWKMVDEDRPRFKDAQTT--L
|.|..|.| .. | .|.||     . .. ......  . |...  |                       || . ....|...  ..|| ....     .
SCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF