Gene SFK6 (Sea Urchin)

SFK6

Species: Sea Urchin
Alias: SFK6, SPU_014473, Spk289
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Echino1

Sequence

Name Sequence Type Origin Length Description Download
SFK6.AA Protein None 324 None Fasta, JSON
SFK6.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of SFK6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 SFK6.AA SH2 4-25 34 0.000239 14.59 Pfam 59-81 (81) Show / Hide 
Range on Protein: 4-25
Range on HMM: 59-81/81
Sequence Identity: 34% (8 aa)

GNS-FFIFQGSVFPTVSELVRHY
.|  ..|. .  |....||| ||
DNGGYYITGRHKFCSLQELVEHY
Kinase SFK6.AA Src-Echino1 63-313 80 1.9e-188 632.35 In-house 1-252 (252) Show / Hide 
Range on Protein: 63-313
Range on HMM: 1-252/252
Sequence Identity: 80% (202 aa)

GQMNRRLGEGKFGEVWQGVWNGNTPVAVKTLKERTMSPAAFLAEANVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSNGDLRTYLKSDKCKNTKMTTLID
..|....|.|..||||.||||||||||||||||.|||||.||||||||||.|||||||.||||||||||||||||||||.|..|||..|||..|||||||
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGRAQLMEKDVYVGEEGAKLPLKWTAPEAVLHGRFTIKSDVWSFGILMTEMVTFGGYPYKK
||||||||||||||||||||||||||||||||||.||||||.|..|.||||.|..|||||.|||||||.|.|||||||||||||||||||||||.|||..
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPG

MRTREVTKKVANGYRMPKMDHCTDSLYMI-MLKCWHKDPQQRPTFKYLHDYF
|..|||...|..|||||||.||.|||||. |.|||||||||||||..|||.|
MMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase SFK6.AA Src 63-313 61 1.4e-180 606.16 In-house 1-255 (255) Show / Hide 
Range on Protein: 63-313
Range on HMM: 1-255/255
Sequence Identity: 61% (158 aa)

GQMNRRLGEGKFGEVWQGVWNGNTPVAVKTLKERTMSPAAFLAEANVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSNGDLRTYLK-SDKCKNTKMTTLI
 .. |.||.|.|||||.|.|||||.|||||||. ||||.|||.||..||||||| .||||||||..||||||||.||.| | .||| ...... ....||
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGRAQLME--KDVYVGEEGAKLPLKWTAPEAVLHGRFTIKSDVWSFGILMTEMVTFGGYP
||.|..|.||.||.|.|..||||||||||||..||.|.|||| |.|..  .|.|. ..|||.| |||||||...|||||||||||||||.||.||.| .|
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YKKMRTREVTKKVANGYRMPKMDHCTDSLYM-IMLKCWHKDPQQRPTFKYLHDYF
|. |. .|| ..| .|||||....| |.||. |||.||||||.|||||.||....
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase SFK6.AA SFK-Src 64-313 53 1.8e-148 443.51 In-house 2-259 (259) Show / Hide 
Range on Protein: 64-313
Range on HMM: 2-259/259
Sequence Identity: 53% (139 aa)

QMNRRLGEGKFGEVWQGVWNGNTPVAVKTLKERTMSPAAFLAEANVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSNGDLRTYLKSDKCKNTKMTTLIDM
.. ..||.| ||.||.|.||. | |||||||  .||   ||.|| |||||||.  .|||||| |.|||||.|||| .| |  ||.. . .  .| .|.||
RLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVDM

GAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGRAQLMEKD-V-YVGEEGAKLPLKWTAPEAVLHGRFTIKSDVWSFGILMTEMVTFGGYPYK
.| .|.|| ||  .| |||||||||||||  ||.|..||| .  ...|   |  .|||| | ||||||| .  || ||||||||||||.|.||.|  || 
AAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPYP

KMRTREVTKKVAN--GYRMPKMDHCTDSLYMIMLKCWHKDPQQRPTFKYLH----DYF
 |   || ..|    |||||.   | | .| ||. || . |  ||||  |     |.|
GMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase SFK6.AA Pkinase_Tyr 64-313 47 4.3e-132 447.99 Pfam 2-270 (270) Show / Hide 
Range on Protein: 64-313
Range on HMM: 2-270/270
Sequence Identity: 47% (127 aa)

QMNRRLGEGKFGEVWQGVWN-----GNTPVAVKTLKERTMSP----AAFLAEANVMKKL-RHEGIVQLYAVCS-DKEP--IYIVTELMSNGDLRTYLKSD
.... |||| ||||..|.|.     ...|||||.||| .|..    ..|..||..||.| .|. ||.||.||. ..||  ||||.|.| .|||..||.. 
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

--KCKNTKMTTLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGRAQLM-EKDVY-VGEEGAKLPLKWTAPEAVLHGRFTIKSDVWSFG
    .. .| .|..| . ||.||.|| ||| .||||||||.||...|||||.||| | .. ..| | .  .|.||| ||.|||.  .|.||.||||||||
REDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFG

ILMTEMVTFGGYP-YKKMRTREVTKKV-ANGYRMPKMDHCTDSLYMIMLKCWHKDPQQRPTFKYLHDYF
.|| |..|.|. | |. |   || ...  .|||||. ..|.| .|..|..|||.||..||||...|  .
VLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase SFK6.AA Src-Unclassified 64-313 49 1e-131 443.88 In-house 2-284 (284) Show / Hide 
Range on Protein: 64-313
Range on HMM: 2-284/284
Sequence Identity: 49% (139 aa)

QMNRRLGEGKFGEVWQGVWNGNTPVAVKTLKER---TMSPAAFL--------AEANVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSNGDLRTYLKSDKC
.  | || | ||||| | | |   |||||...    ||||.|||        .||..|||.||  .|.||||||. ||.||.||.|.|| |  .|. .  
HLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGGG

KNTKMTTL------------IDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGN-----VVKIADFGRA--QLMEKDVYVGEEGAKLPLKWTAPEAVLH
.   .  .            .|. | .||||.|| ||  |||||||||||.|  |     |||..||| |   ||. | |.   ||..| ||.|||... 
QYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFIY

GRFTIKSDVWSFGILMTEMVTFGGYPYKKMRTREVTKKVANGYRMPKM--DHCTDSLYM-IMLKCWHKDPQQRPTFKYLHDYF
| |.|||||||.|||  |. | |  ||  |  ||| . |  ||||||     | |..|  ||.||||||||.||||  |  ||
GNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase SFK6.AA SrcA 64-313 57 6.00000000001e-131 416.22 In-house 2-250 (250) Show / Hide 
Range on Protein: 64-313
Range on HMM: 2-250/250
Sequence Identity: 57% (144 aa)

QMNRRLGEGKFGEVWQGVWNGNTPVAVKTLKERTMSPAAFLAEANVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSNGDLRTYLKSDKCKNTKMTTLIDM
.. ||||.| ||||| | |||.| ||.||||  |||| ||| || .||||||. .|||||| |. |||||||| |. | |  .|| .. |. |.  |.||
RLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSE-EPIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVDM

GAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGRAQLMEKDVYVGEEGAKLPLKWTAPEAVLHGRFTIKSDVWSFGILMTEMVTFGGYPYKKM
 | .|.|| |.   | .|||| | |.|||.  . |||||| | |.| . |  . ||| |.||||||| |.|||||||||||||||.||.|| |  ||  |
AAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGM

RTREVTKKVANGYRMPKMDHCTDSLYMIMLKCWHKDPQQRPTFKYLHDYF
  |||  .|  ||.||  . |  ||. .| .||.|||. |||| ||  . 
NNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase SFK6.AA TyrKc 63-313 43 2e-127 430.52 SMART 1-280 (280) Show / Hide 
Range on Protein: 63-313
Range on HMM: 1-280/280
Sequence Identity: 43% (123 aa)

GQMNRRLGEGKFGEVWQGVWNGNTPVAVKTLKERTMSPAAFLAEANVMKKL--RHEGIVQLYAVCSDK-------EPIYIVTELMSNGDLRTYLKSDKCK
 .... |||| ||||..|.|.  ..||||.||| .   ..|. ||..|.||  .|. ||.||.||...       ||..||.|.|..|||. ||.. . |
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

NTKMTTLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGRAQLMEKD--------VYVGEE--GAK--LPLKWTAPEAVLHGRFTIKSD
  .| .|...   ||.||.|| |||..||||||||.|||....|||.||| .   . |        .|.  |  |.|  ||..|.|||.  .|.||.|||
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWSFGILMTEMVTFGGYPYKK-----MRTREVTKKVANGYRMPKMDH--------CTDSLYMIMLKCWHKDPQQRPTFKYLHDYF
|||||..| |. |.|. ||       |  .|| ..| .|||||....        |.| .|.||..||| || .||||. .|..|
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase SFK6.AA Frk 64-313 57 2.5e-123 416.03 In-house 2-260 (260) Show / Hide 
Range on Protein: 64-313
Range on HMM: 2-260/260
Sequence Identity: 57% (149 aa)

QMNRRLGEGKFGEVWQGVWNGNTPVAVKTLKERTMSPAAFLAEANVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSNGDLRTYLK--SDKCKNTKMTTLI
|. |||| |.||||| | || .|||||||||  || |  ||.|| .||||||  ..||||||  .|||||.|||| .| | .||.  .|| .. .|..|.
QLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQLV

DMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGRAQ-LMEKDV--YVGEEGAKLPLKWTAPEAVLHGRFTIKSDVWSFGILMTEMVTFGGY
|| | .|.|| || |.| .||||||||||||..|..|||||| |  ||  .   |    ||..|.|||||||.   .|||||||||||||.||..|.|  
DMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGRM

PYKKMRTREVTKKVANGYRMPKMDHCTDSLYMIMLKCWHKDPQQRPTFKYLH----DYF
||  |  .|| . |..|||||.   |   || |||.|||.||..||||  |.    |||
PYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase SFK6.AA TK 63-313 26 2.6e-116 391.61 In-house 1-486 (486) Show / Hide 
Range on Protein: 63-313
Range on HMM: 1-486/486
Sequence Identity: 26% (129 aa)

GQMNRRLGEGKFG---EVWQGVWNGN--------------------------TPVAVKTLKER-TMSPAAFLA--------------EANVMKKLR----
 .. . |||| ||   ||..| |.|                           ||||||.|||  .||...|..              ||..||...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HEGIVQLYAVCSDK------------EPIYIVTELMSNGD----LRTYLKSDKCK--------------------------------------------
 |. ||.||.||...            ||..||.|.|..||    ||.||.. . |                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------NTKMTTLIDMGAHIASGMDYLGSK------NVVHRDLAARNVLVGKGNV-----------VKIADFG---
                              .  | .|. | . ||.|| || ||      |.|||||||||.|||..||           .||||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----RAQLMEKD-VYVGEE------------------------GAKLPLKWTAPEAVL---------HGRFTIKSDVWSFGILMTEMVTFGGYPYKKMR
     .|  ...|  |.  .                        |.|||..|.|||...         .|.||.||||||||.|| |..|.|  ||  . 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

T----------REVTKKVANG--------------YRMPKMDHCT--------------DSLYMIMLKCWHKDPQQRPTFKYLHDYF
.          .|| ... .|              .|||. .||.              . .| .|..|||.||..||||. ||...
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase SFK6.AA SrcB 64-314 53 8.49999999999e-115 387.68 In-house 2-251 (251) Show / Hide 
Range on Protein: 64-314
Range on HMM: 2-251/251
Sequence Identity: 53% (134 aa)

QMNRRLGEGKFGEVWQGVWNGNTPVAVKTLKERTMSPAAFLAEANVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSNGDLRTYLKSDKCKNTKMTTLIDM
.. ..|| |.||||| | .|... |||||.|. |||| ||||||||||.| |. .|.|||| . ||||||.|| | .| |  .||.|.    ..  ||||
KLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVT-KEPIYIITEYMAKGCLLDFLKTDEGSKLSLPKLIDM

GAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGRAQLMEKDVYVGEEGAKLPLKWTAPEAVLHGRFTIKSDVWSFGILMTEMVTFGGYPYKKM
 | || || |.  .| .|||| | |.|| .  . |||||| | ..| . |   |||| |.|||||||. .| |||||||||||||..|.||.|  ||  |
SAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPGM

RTREVTKKVANGYRMPKMDHCTDSLYMIMLKCWHKDPQQRPTFKYLHDYFV
   || . .  |||||..| | . || || .||.. | .|||| ||.    
TNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase SFK6.AA SRM 64-314 46 1.2e-104 350.98 In-house 2-253 (253) Show / Hide 
Range on Protein: 64-314
Range on HMM: 2-253/253
Sequence Identity: 46% (116 aa)

QMNRRLGEGKFGEVWQGVWNGNTPVAVKTLKERT-MSPAAFLAEANVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSNGDLRTYLKSDKCKNTKMTTLID
 . |.|||| ||||| | | |  .||.|  |    |  . . .|   ||||||. |. |.||||  .|.||.||||  | |  ||..   |  ..  |.|
TLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLLD

MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGRAQLMEKDVYVGEEGAKLPLKWTAPEAVLHGRFTIKSDVWSFGILMTEMVTFGGYPYKK
.   .| || || ..|..|||||||||||| .|. |..||| | |.  |.|    . . | |||||||.  . . .||||||||||. || | |  ||  
FACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYPG

MRTREVTKKVANGYRMPKMDHCTDSLYMIMLKCWHKDPQQRPTFKYLHDYFV
|   |   ..  |||||    |  . .  ||.|| .||.|||.|| |     
MTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase SFK6.AA Abl 64-313 44 1.4e-97 326.12 In-house 2-252 (252) Show / Hide 
Range on Protein: 64-313
Range on HMM: 2-252/252
Sequence Identity: 44% (112 aa)

QMNRRLGEGKFGEVWQGVWNG-NTPVAVKTLKERTMSPAAFLAEANVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSNGDLRTYLKSDKCKNTKMTTLID
 |  .|| |..|||..|||   .  |||||||| ||    ||.|| .||...|. .|||  ||    | ||.|| |..| |  ||.. . .. .  .|. 
MMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLLY

MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGRAQLMEKDVYVGEEGAKLPLKWTAPEAVLHGRFTIKSDVWSFGILMTEMVTFGGYPYKK
| . |||||.|| ... .|||||||| |||  ..||.|||| | .|..|.|  . ||| |.||||||.. . .| .||||| ||.|. |. |.|  ||  
MATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYPG

MRTREVTKKVANGYRMPKMDHCTDSLYMIMLKCWHKDPQQRPTFKYLHDYF
.   .| .|. .|||| . . | .. | .|..||. ..  ||.|| .|  .
IDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase SFK6.AA S_TKc 63-313 24 2.2e-51 177.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 63-313
Range on HMM: 1-231/231
Sequence Identity: 24% (66 aa)

GQMNRRLGEGKFGEVWQGVWNG-NTPVAVKTLKERTMSPAAFLAEANVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSN--GDLRTYLKSDKCKN----T
 .. | .|.| ||.|....... .  ||.| .|        .. | ...|| .|. ||.|| |. | . .|.|.|....  |||..|.|. ...      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

KMTTLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGRAQLMEKDVYVGEEGAKLPLKWTAPEAVLHGRFTI-KSDVWSFGILMTEMVT
   .   . . |.....|. |....||||   |.|. .  ..||.||| | ..              . . ||| .    ..  |.|.||.|... ||..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

FGGYPYKKMRTREVTKKVANGYRMPKMDHCTDSLYMIMLKCWHKDPQQRPTFKYLHD---------YF
 |  |.      .. ||.            ....  .. ||..|||..|||   .           .|
-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SFK6.AA Pkinase 63-313 24 1.9e-43 154.68 Pfam 1-293 (293) Show / Hide 
Range on Protein: 63-313
Range on HMM: 1-293/293
Sequence Identity: 24% (73 aa)

GQMNRRLGEGKFGEVWQGVWNGN-TPVAVKTLKERTMSP----AAFL-AEANVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSNG----DLRTYLK-SDK
 .  |..|.| ||.|..... |.   ||||..| |. ..    .... .|. .||.|.|. ||.|| .. ||  ||.|.|.. .|    || .|.. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

CKN-TKMTTLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVG-KGNV---VKIADFGRAQLMEKDVYVGEEGAKLP---LKWTAPEAVL-HGRFTIKSDV
..    . .....   |..|..|. |....||||   |.|.  .|..   |||.||| | ...   |   . .. .   . . ||| .. .   . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSFGILMTEMVTFGGYPYKKM----RTREVTKKVANGYRMPKMDHCT-----------------------DSLYMIMLKCWHKDPQQRPTFKYL--HDYF
||.|... ||.. |  |..      . ..  .....  . | . ..                        ...  .. .|..|||..|||.. .  |..|
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF