Gene TK3 (Sea Urchin)

TK3

Species: Sea Urchin
Alias: TK3, SPU_009842, Spk272
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TK
Family: TK-Sp1

Sequence

Name Sequence Type Origin Length Description Download
TK3.AA Protein None 458 None Fasta, JSON
TK3.kin_dom Protein Kinase Domain None 223 None Fasta, JSON

Protein domain

Protein domains of TK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TK3.AA TK-Sp1 40-309 63 5.1e-212 710.65 In-house 1-270 (270) Show / Hide 
Range on Protein: 40-309
Range on HMM: 1-270/270
Sequence Identity: 63% (172 aa)

VEVREQLGSGQFGVVYSGRLLGRTDSWKHVPVAVKMVKDHVSDLMKLDLLNEIRLMFELGGHQHVLEVIACCTVKFPYYMITEMLKYGDLLHFLRKCNKP
. .  .||.||||.||    .|     ..|||||| ..      || |.||||.||||||.|.|.|..|.||||..|.||||||.|||||||||.||...
LKIEKELGAGQFGIVYKAFAFGLNGIKEYVPVAVKSLRVNATPGMKEDFLNEIKLMFELGQHPHILQIIGCCTVHEPHYMITEMMKYGDLLHFLWKCRED

RHIEKDPIYDITDLQRYQIARQIASGMVFISSKRFYHGDLAARNILVGTDLMVKISDFGLSSDIYQVGYQRLSPERKRPIKWASIETNIEGKCTIQSDIW
.||..|||||.||.|.|||.||||.||..||..|.|||||||||.|||..||.|||||||..||||.||.||.||||||.||.|.|||..||||||||.|
KHIRQDPIYDLTDTQQYQICRQIARGMEYISKTRYYHGDLAARNVLVGKGLMCKISDFGLADDIYQRGYKRLAPERKRPVKWVSLETNTQGKCTIQSDVW

SYGITLYEIFTNGEMPYKDMPSREVLRRVRDGYRMEKPENCPDDVYKMMSLCWHEKPIGRPAFKNLFNFF
|.||..|||.|||.|||..|..|||.....||||||||.|||.|||.||..||||.|..||.|||.||||
SFGIVMYEIYTNGGMPYPGMDGREVISKLQDGYRMEKPDNCPEDVYDMMRACWHEHPHHRPTFKNIFNFF
Kinase TK3.AA Pkinase_Tyr 40-309 39 3.1e-112 380.72 Pfam 1-270 (270) Show / Hide 
Range on Protein: 40-309
Range on HMM: 1-270/270
Sequence Identity: 39% (109 aa)

VEVREQLGSGQFGVVYSGRLLGRTDSWKHVPVAVKMVKDHVSDLM--KLDLLNEIRLMFELGGHQHVLEVIACCT-VKFP--YYMITEMLKYGDLLHFLR
..  ..||.|.||.|| |.. |  .. ...||||||.|.. ..    . |...|...| .|| |....  ...||  . |  .|...|  ..||||..||
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KCNKPRHIEKDPIYDITDLQRYQIARQIASGMVFISSKRFYHGDLAARNILVGTDLMVKISDFGLSSDIYQVGYQ-RLSPERKRPIKWASIETNIEGKCT
|         ..   .|  .  |...|||.|| . .||.. | ||||||.||. .. |||.||||. |||  .|  | . . | |||| . |   .||.|
KHR-------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFT

IQSDIWSYGITLYEIFTNGEMP-YKDMPSREVLRRV-RDGYRMEKPENCPDDVYKMMSLCWHEKPIGRPAFKNLFNFF
..||.||.|....|||| ||.| |..|.  ||.... .|||||..||||||..|..| .|||..|  || |. . ...
TKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase TK3.AA TyrKc 40-309 35 8.9e-110 371.92 SMART 1-280 (280) Show / Hide 
Range on Protein: 40-309
Range on HMM: 1-280/280
Sequence Identity: 35% (106 aa)

VEVREQLGSGQFGVVYSGRLLGRTDSWKHVPVAVKMVKDHVSDLMKLDLLNEIRLMFELG-GHQHVLEVIACCTVK-------FPYYMITEMLKYGDLLH
..  ..||.|.||.|| |..         ..|||||.|..     . |...|.|.| .||  |....  ...|| .        |.....|  ..|||..
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

FLRKCNKPRHIEKDPIYDITDLQRYQIARQIASGMVFISSKRFYHGDLAARNILVGTDLMVKISDFGLSSDIYQV-------GYQRLS--PERK--RPIK
.|||. .           ..  .  ... |||.|| ...||.. | ||||||.||| .. ||||||||| |||          | | .    .|   ||.
YLRKHRPK----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR

WASIETNIEGKCTIQSDIWSYGITLYEIFTNGEMPYKD-----MPSREVLRRVRDGYRMEKPEN--------CPDDVYKMMSLCWHEKPIGRPAFKNLFN
| ..|.  .||.|..||.||.|....||||.|..|| .     |. .||...|..||||..|.|        |||..|..|. ||||.|  || |...  
WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

FF
.|
CF
Kinase TK3.AA TK 40-309 22 7.89999999999e-108 362.68 In-house 1-486 (486) Show / Hide 
Range on Protein: 40-309
Range on HMM: 1-486/486
Sequence Identity: 22% (108 aa)

VEVREQLGSGQFG---VVYSGRLLGRTD--------------------SWKHVPVAVKMVK--DHVSDLMKLD--------------LLNEIRLMFE-LG
... ..||.||||   .|| |.. || .                    . ...||||||.|  |. |. ...|              ...|. .| . ||
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

GHQHVLEVIACCTVK------------FPYYMITEMLKYGD----LLHFLRKCNKPRHIEKDPIYD----------------------------------
 |....  ...|| .             |.....|. ..||    |...|||| .... | | ...                                  
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------ITDLQRYQIARQIASGMVFISSK------RFYHGDLAARNILVGTDLM-----------VKISDFG---
                               .|  |.  ...|||.|| ...||      .| |.||||||.||| ..            .||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSSDIYQVGYQRLSP------------------------ERKRPIKWASIETNI---------EGKCTIQSDIWSYGITLYEIFTNG-EMPYKDM
     |. |||. .. . .                          .| ||.| . |.           .||.|..||.||.|....||||.| |..| .|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

PS---------REVLRRVRDG--------------YRMEKPENCP--------------DDVYKMMSLCWHEKPIGRPAFKNLFNFF
..         .||....|.|              .||..|..||              ...| .|  |||..|  || |. | ...
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase TK3.AA TK-Unique 40-309 35 5.4e-96 325.21 In-house 1-294 (294) Show / Hide 
Range on Protein: 40-309
Range on HMM: 1-294/294
Sequence Identity: 35% (104 aa)

VEVREQLGSGQFGVVYSGRLLGRT-DSWKHVPVAVKMVKDHVSDLMKLDLLNEIRLMFELGGHQHVLEVIACCTVKF-PYYMITEMLKYGDLLHFLRKCN
.|| ...|.|.|| |. | . |.. .. |.. |||||.||...|. | |.|.||..| ||| |....  . ||| .. | ..| | . .|.|.|.||.| 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

KP---------------RHIEKDPIYDITDLQRYQIARQIASGMVFISS--KRFYHGDLAARNILVGTDLMVKISDFGLSSDIYQ-VGYQRLSPERKRPI
..               .. .|.. ..|.  . |..| |||.|| ...|  |.. |.||.|||.|.. |...||.|||.. |.|    |..   . . ||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWASIETNI--EGKC-TIQSDIWSYGITLYEIFTNGEMPYKDMPSREVLRRVRDGYRMEKPENC-PDDVYKMMSLCWHEKPIGRPAFKNLFNFF
.| . |     .| . |..||.||.|....||||.|..|| .||........||||||..||.| ....|. |. ||...|  || |  . . .
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase TK3.AA UTK 40-309 30 1.1e-81 277.7 In-house 1-296 (296) Show / Hide 
Range on Protein: 40-309
Range on HMM: 1-296/296
Sequence Identity: 30% (91 aa)

VEVREQLGSGQFGVVYSGRLLG----RTDSWKHVPVAVKMVKDHVSDLMKL---DLLNEIR---LMFELGGHQHVLEVIACCTVKFPYYMITEMLKYGDL
|. ..|||.|.||.|. .|.      .... . |.|..   .....   .    |...| |   .|  . .|..|| ... ||   | ...||. . |||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ---HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDL

LHFLRKCNKPRHIEKDPIYDITDLQRYQIARQIASGMVFISSKRFYHGDLAARNILVGTD-------LMVKISDFG---LSSDIY---------QVGYQR
...||.. .      ..    |. || . |..||.|| ...|..| |.||||||.||. .       . .||.|||   .| ...         .  | .
RSYLRRHRPTPP---ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYM

LSPERKRPIKWASIETNIEG-KCTIQSDIWSYGITLYEIFTNGEMPYKDMPSREVLRRVRDG--YRMEKPENCPDDVYKMMSLCWHEKPIGRPAFKNLFN
 .. .. ||.| . |  ... . |..||.||.|....||.|.| .||..|  ..|. .|..|  |||..|. ||..||..|  |||  |  || |. |  
AQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQ

FF
..
QM
Kinase TK3.AA Src 40-309 36 6.1e-80 271.28 In-house 1-255 (255) Show / Hide 
Range on Protein: 40-309
Range on HMM: 1-255/255
Sequence Identity: 36% (100 aa)

VEVREQLGSGQFGVVYSGRLLGRTDSWKH-VPVAVKMVKDHVSDLMKLDLLNEIRLMFELGGHQHVLEVIACCTVKFPYYMITEMLKYGDLLHFLRKCNK
.   ..||.|||| |. |        |.  ..||||  |     .   ..| |. .| .|  |.....  | |. . |.| .||  . | || .|.|   
IKLCRKLGQGQFGEVWMGY-------WNGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKL-RHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK---

PRHIEKDPIYDITDLQRYQIARQIASGMVFISSKRFYHGDLAARNILVGTDLMVKISDFGLSSDIYQVG---YQRLSPERKRPIKWASIETNIEGKCTIQ
     ..    .   |   .| |.|.|| ...|... | ||||||.|||.....|. ||||   . ...   |   . . | ||||   |   .|. || 
-----DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKEDDDEYCARH-GAKFPIKWTAPEAINYGRFTIK

SDIWSYGITLYEIFTNGEMPYKDMPSREVLRRVRDGYRMEKPENCPDDVYK-MMSLCWHEKPIGRPAFKNLFNFF
|| ||.|| |.||.| | .||. |  .|||..|  |||| .|.|||| .|.  |  |||..|  || |. |..|.
SDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase TK3.AA KIN6 40-309 30 9.9e-67 219.49 In-house 1-305 (305) Show / Hide 
Range on Protein: 40-309
Range on HMM: 1-305/305
Sequence Identity: 30% (95 aa)

VEVREQLGSGQFGVVYSGRLLG------RTDSW---------KHVPVAVKMVKDHVSDLMKLDLLNEIRLMFELGGHQHVLEVIACCTVKFPYYMITEML
.   . ||.| |. || | . |        ..           . ..||||.  |  .  ..|.. || .|  || | |.    .| |.  . . . |  
IHKDHKLGHGAFCNVYKGKIKGKSPIMQWINRVNMRIEMMRYQDCQCAVKMLPSHADEMAHHDFMHEIAFMKQLGHHPHLVNMLGCVTNSYKPCLVVEYC

KYGDLLHFLR-KC----N---------KPRHIE---KDPIYDITDLQRYQIARQIASGMVFISSKRFYHGDLAARNILVGTDL---MVKISDFGLSS--D
  .|||..|| .|    |          |  ..    . .  . ||  |..| ||. || ...||.. | ||||||.|| . .     ||||||| .  .
CHMDLLKYLRNRCQYMMNLDDLGINYHCPDENSRYDDMMCIRHKDL--YMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPY

IYQVGYQRLSPERKR--PIKWASIETNIEGKCTIQSDIWSYGITLYEIFTNGEMPYKDMP-SREVLRRVRDGYRMEKPENCPDDVYKMMSLCWHEKPIGR
  | .|  ..    |  |||| . |  .  .  . ||.||.|. ..|.|. |. || .|.   |..   | | |...|..||. .|. |..|| |||  |
MDQFQYTSKG---GRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDR

PAFKNLFNFF
|.|  . . |
PEFNEMRMQF
Kinase TK3.AA Src-Echino1 40-309 38 4.4e-63 215.9 In-house 1-252 (252) Show / Hide 
Range on Protein: 40-309
Range on HMM: 1-252/252
Sequence Identity: 38% (104 aa)

VEVREQLGSGQFGVVYSGRLLGRTDSWKHVPVAVKMVKDHVSDLMKLDLLNEIRLMFELGGHQHVLEVIACCTVKFPYYMITEMLKYGDLLHFLRKCNKP
... ...|.|..| |. |   | |      ||||| .| .   . . |.| |  .| ..  |. .. . | |  | | |..||... |.|...| | .| 
LRMDKKIGKGHCGEVWKGVWNGNT------PVAVKTLKEKT--MSPADFLAEANVMKKC-RHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYL-KRGKC

RHIEKDPIYDITDLQRYQIARQIASGMVFISSKRFYHGDLAARNILVGTDLMVKISDFGLSSDIYQVGYQRLSPERKRPIKWASIETNIEGKCTIQSDIW
.|.       .| |    .  .||||| .. || . | ||||||.|||.  ..|| ||||   . .  |       | |||| . |  . |. ||.||.|
KHVK------MTTL--IDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQ-GAKLPIKWTAPEAALYGRFTIKSDVW

SYGITLYEIFTNGEMPYKDMPSREVLRRVRDGYRMEKPENCPDDVYKM-MSLCWHEKPIGRPAFKNLFNFF
|.|| . |. | | .||..|  |||| .|  |||| |...||| .|.| |  |||  |  ||.|. | .||
SFGILMTEMVTFGRYPYPGMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase TK3.AA Frk 40-313 37 3.5e-62 212.88 In-house 1-260 (260) Show / Hide 
Range on Protein: 40-313
Range on HMM: 1-260/260
Sequence Identity: 37% (103 aa)

VEVREQLGSGQFGVVYSGRLLGRTDSWKHVPVAVKMVKDHVSDLMKLDLLNEIRLMFELGGHQHVLEVIACCTVKFPYYMITEMLKYGDLLHFLRKCNKP
...  .||||||| |. |.          .||||| .|    |    |.| | ..| .|  |  .... | |||. | |.|||... | |...|.  |. 
IQLIRRLGSGQFGEVWEGLWN------NTTPVAVKTLKPGTMDPN--DFLREAQIMKKL-RHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDK

RHIEKDPIYDITDLQRYQIARQIASGMVFISSKRFYHGDLAARNILVGTDLMVKISDFGLSSDIYQVGY--QRLSPERKRPIKWASIETNIEGKCTIQSD
 .        .   |  ..| |.|.|| .. |. . | ||||||.||| ....|| ||||   . .          . . ||||   |     | ||.||
GR-------QCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSD

IWSYGITLYEIFTNGEMPYKDMPSREVLRRVRDGYRMEKPENCPDDVYKMMSLCWHEKPIGRPAFKNLFNFFDKKI
.||.|| |.|| | | |||  |  .|||  |  |||| .| |||  .|..|  |||..|  || |  |   ... .
VWSFGILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase TK3.AA FGFR 40-309 35 6.7e-62 209.74 In-house 1-293 (293) Show / Hide 
Range on Protein: 40-309
Range on HMM: 1-293/293
Sequence Identity: 35% (105 aa)

VEVREQLGSGQFGVVYSGRLLGRTDS--WKHVPVAVKMVKDHVSDLMKLDLLNEIRLMFELGGHQHVLEVIACCTVKFPYYMITEMLKYGDLLHFLRKCN
  . . || | || |  .   |   .   | . |||||.|.  .|    ||  |.  |   | |. ..  . |||   | | | |  . | |  |||. .
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRA-R

KPRH------IE-------KDPIYD--------ITDLQRYQIARQIASGMVFISSKRFYHGDLAARNILVGTDLMVKISDFGLSSDIYQVGYQRLSPERK
 |        ..       . |           .|  .  ..| |.| || .  |..  | ||||||.||. |   ||.||||. || .. | |   .  
RPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNGR

RPIKWASIETNIEGKCTIQSDIWSYGITLYEIFTNGEMPYKDMP-SREVLRRVRDGYRMEKPENCPDDVYKMMSLCWHEKPIGRPAFKNLFNFF
 ||||   |   . . | |||.||||. | ||.| |. ||   |   |     . |.|||||.||. ..| ||  |||.||  || || |   .
LPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase TK3.AA CTKB 40-305 37 6.8e-61 208.62 In-house 1-263 (269) Show / Hide 
Range on Protein: 40-305
Range on HMM: 1-263/269
Sequence Identity: 37% (101 aa)

VEVREQLGSGQFGVVYSGRLLGRTDSWKHVPVAVKMVKDHVSDLMKLDLLNEIRLMFELGGHQHVLEVIACCTVKFPYYMITEMLKYGDLLHFLRKCNKP
. .. .|| | ||||| |            |||.||..|  |.    | . |...|  . | | .  ..  ||   |. |. |..  |||   ||     
IVLKQKLGEGHFGVVYAGEAKKIMPDQAVTPVAIKMLQDSSSEATN-DFMKEVKIMQTIDGDQKIVRLLGICTRETPFLMVLELMAKGDLKTLLRNS---

RHIEKDPIYDITDLQRYQIARQIASGMVFISSKRFYHGDLAARNILVGTDLMVKISDFGLSSDIYQVGYQRLSPERKRPIKWASIETNIEGKCTIQSDIW
|     |   .       .|  .| || .| |||  | |||||| ||  .  | | |||.| |.|   |  ..     || | | |    |  | |||.|
RPKTSKPSA-LSPRRLALMAADVADGMAYIASKRIVHRDLAARNCLVHQNWRVCIGDFGISRDVYMREYYKMQASNPLPIRWMSPESINDGVYTTQSDVW

SYGITLYEIFTNGEMPYKD-MPSREVLRRVRDG-YRMEKPENCPDDVYKMMSLCWHEKPIGRPAFKNL
|||| ..|| | . ||| .     ||  |. |. ||| .|. |||..| .|  || | |  |. || |
SYGIVIWEIMTFAKMPYPEYETNMEVVERICDEDYRMWQPKECPDEFYDLMMQCWDEEPDDRISFKEL
Kinase TK3.AA S_TKc 40-309 18 5.2e-24 87.0 SMART 1-231 (231) Show / Hide 
Range on Protein: 40-309
Range on HMM: 1-231/231
Sequence Identity: 18% (52 aa)

VEVREQLGSGQFGVVYSGRLLGRTDSWKHVPVAVKMVKDHVSDLMKLDLLNEIRLMFELGGHQHVLEVIACCTVKFPYYMITEMLKY--GDLLHFLRKCN
 |. ...|.| ||.|| .|  .      .  ||.|..|         ....||... .  .| ..   . ..     .||..|..    |||.....|..
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

KPRHIEKDPIYD--ITDLQRYQIARQIASGMVFISSKRFYHGDLAARNILVGTDLMVKISDFGLSSDIYQVGYQRLSPERKRPIKWASIETNIEGKCTI-
...       ..  ..  .   ...||.... .. |... | ||   |||. .   .||.||||.  .                 . . |     . .  
RHG-------LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKC

QSDIWSYGITLYEIFTNGEMPYKDMPSREVLRRVRDGYRMEKPENCPDDVYKMMSLCWHEKPIGRPAFKNLFN---------FF
 .|.|| |..||| .. |. |.      .......           ....  ... |..  |  ||    ...         .|
KCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TK3.AA Pkinase 40-200 25 4.4e-19 68.56 Pfam 1-159 (293) Show / Hide 
Range on Protein: 40-200
Range on HMM: 1-159/293
Sequence Identity: 25% (43 aa)

VEVREQLGSGQFGVVYSGRLLGRTDSWKHVPVAVKMVKDHVSDLMKLD-LLN--EIRLMFELGGHQHVLEVIACCTVKFPYYMITEMLKYG----DLLHF
 .. ...||| ||.|| ..  |  .      |||| .| .  .  |.  ...  ||..| .| .| .... . ... |  .||..| .  |    || ..
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

LRKCNKPRHIEKDPIYDITDLQRYQIARQIASGMVFISSKRFYHGDLAARNILVGTDLMV----KISDFGLS
..        .. ..|  .. .   ...||..|. .. |... | ||   |||.  .  .    ||.||||.
IST------WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase TK3.AA Pkinase 236-309 14 6e-06 22.02 Pfam 193-293 (293) Show / Hide 
Range on Protein: 236-309
Range on HMM: 193-293/293
Sequence Identity: 14% (15 aa)

SDIWSYGITLYEIFTNGEMPYKDM----PSREVLRRVRDGYRMEKPENCP-----------------------DDVYKMMSLCWHEKPIGRPAFKNLFNF
.|.||.|..||| .. |. |...     . .. . ...   . . ....|                       ..  . .. |.. .|  || .. ... 
VDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

--F
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PWF