Gene Spk388 (Sea Urchin)

Spk388

Species: Sea Urchin
Alias: SPU_028625, Spk388
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TK
Family: TK-Unique

Sequence

Name Sequence Type Origin Length Description Download
Spk388.AA Protein None 665 None Fasta, JSON
Spk388.kin_dom Protein Kinase Domain None 161 None Fasta, JSON

Protein domain

Protein domains of Spk388.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Spk388.AA TK-Unique 66-165 36 1.4e-35 120.19 In-house 40-155 (294) Show / Hide 
Range on Protein: 66-165
Range on HMM: 40-155/294
Sequence Identity: 36% (42 aa)

DRDQVSKSTNVLRAVKVLSELLDQPNVVKCLGYCQ---EQGSILYEFISGGTLLTHLQTTG-VQSQP-TYGNLK------PNSVR---VDEGSLLNLAWQ
|. .  .  . |.  ....|| |.||.|.|||.|.   |.  |..|....|.|...|.|.. ...|. ||||||      | ..|   .....|.. |||
DNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQ

IAKGMQYLAS--KKLT
||.||.||||  || .
IACGMEYLASQRKKIV
Kinase Spk388.AA TK 77-163 15 9e-17 52.03 In-house 89-254 (486) Show / Hide 
Range on Protein: 77-163
Range on HMM: 89-254/486
Sequence Identity: 15% (26 aa)

LRAVKVLSE-LLDQPNVVKCLGYCQEQG--------------SILYEFISGGT----LLTHLQTTGV---QSQPTYGNLKPNSVR---------------
... |.... |.. ||.|...|.| ...               |. |. ..|     |...|..      ..|....|...  ..               
AEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSH

-------------------------------------------VDEGSLLNLAWQIAKGMQYLASKK
                                           ..   ||  .||||.||.||.||.
ESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKN
Kinase Spk388.AA Pkinase_Tyr 90-164 30 1.7e-13 46.33 Pfam 64-132 (270) Show / Hide 
Range on Protein: 90-164
Range on HMM: 64-132/270
Sequence Identity: 30% (24 aa)

PNVVKCLGYCQ-EQGS----ILYEFISGGTLLTHLQTTGVQSQPTYGNLKPNSVRVDEGSLLNLAWQIAKGMQYLASKKL
||.|...| |  ....    |  |.  .| ||..|..             ..  ...   ||. .|||||||.||.||..
PNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR-----------EDKQPLTMKDLLQMCWQIAKGMEYLESKNC
Kinase Spk388.AA TKL 87-159 23 4.1e-12 39.91 In-house 82-148 (364) Show / Hide 
Range on Protein: 87-159
Range on HMM: 82-148/364
Sequence Identity: 23% (21 aa)

LDQPNVVKCLGYCQEQG---------------SILYEFISGGTLLTHLQTTGVQSQPTYGNLKPNSVRVDEGSLLNLAWQIAKGMQYL
|. ||.|...|||.. .                | .|...||.|| .|.                        ....| .||.||.||
LRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------------------WHQRCRWALDIARGMNYL
Kinase Spk388.AA MLK 87-159 28 4.6e-10 31.22 In-house 62-140 (291) Show / Hide 
Range on Protein: 87-159
Range on HMM: 62-140/291
Sequence Identity: 28% (23 aa)

LDQPN----VVKCLGYCQEQGS---ILYEFISGGTLLTHLQTTGVQSQPTYGNLKPNSVRVDEGSLLNLAWQIAKGMQYL
|..||    ... .| |.....   |. |...|| | . | .   .. .   | | |....| ....| | |.|.||.||
LSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQK-NDRVYDHDHAMNWALQCARGMHYL
Kinase Spk388.AA UTK 87-164 25 1.5e-07 21.95 In-house 66-139 (296) Show / Hide 
Range on Protein: 87-164
Range on HMM: 66-139/296
Sequence Identity: 25% (22 aa)

LD-QPNVVKCLGYCQEQGS--ILYEFISGGTLLTHLQ----TTGVQSQPTYGNLKPNSVRVDEGSLLNLAWQIAKGMQYLASKKL
..  |||.. .|.|  ..   |..|. ..| |.. |.    |..           .. . ... ..|  ||.|| |||||.|...
FHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPP-----------ACPHWLTLHQRLCMAWDIARGMQYLHSCGF
Kinase Spk388.AA TKL-Unique 83-159 26 2e-06 18.79 In-house 48-126 (290) Show / Hide 
Range on Protein: 83-159
Range on HMM: 48-126/290
Sequence Identity: 26% (22 aa)

LSELLD-QPNVVKCLGYCQ----EQG--SILYEFISGGTLLTHLQTTGVQSQPTYGNLKPNSVRVDEGSLLNLAWQIAKGMQYL
... |.  ||.|.. |||      ..  .|  |...||.|  .|..    .     |  .|.   .    ...| .||.|| ||
WMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN-----NNNNNNCKLNMQQRVKMAIDIAQGMYYL
Kinase Spk388.AA Ciliate-E2 60-163 16 6e-06 16.43 In-house 53-180 (365) Show / Hide 
Range on Protein: 60-163
Range on HMM: 53-180/365
Sequence Identity: 16% (22 aa)

EMIQNGDRDQVSKSTNVLR---------AVKVLSELLDQPNVVKCLGYCQEQGS----ILYEFISGGTLLTHLQ-----TTGVQSQPTYGNLKPNSVRVD
..... .  |...  ...|           | . |.|. ||..|.  . ||.      .  |...||.|. ...      .  ..       |    . .
KIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE-------K-D-KYFT

EGSLLNLAWQIAK---------------GMQYLASKK
|   ... .||..               ...|| ||.
EKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKN
Kinase Spk388.AA Src 108-164 26 4.4e-05 13.15 In-house 74-118 (255) Show / Hide 
Range on Protein: 108-164
Range on HMM: 74-118/255
Sequence Identity: 26% (15 aa)

EFISGGTLLTHLQTTGVQSQPTYGNLKPNSVRVDEGSLLNLAWQIAKGMQYLASKKL
|. | | ||. |.             ..   ..    |. .|.|.|.||.|| |...
EYMSHGSLLDYLKK------------DGEGRHLHLPQLIDMAAQVAEGMAYLESMNY
Kinase Spk388.AA IG 162-275 13 0.000211 21.87 SMART 1-58 (58) Show / Hide 
Range on Protein: 162-275
Range on HMM: 1-58/58
Sequence Identity: 13% (16 aa)

KKLTEFSNGQSVTLTGPSAIEQGSDTVYICTGGPSPYNFLWQDFSLGTGVNIFLAGEVAYDPLVLPKYINFDVAENGDTSTMTITNTVIEDE---GRYRC
 . .. . |..||||   .                  .. |                                        .|| |   ||.   | |.|
PP-VTVKEGETVTLTC-VS------------------QIWWY---------------------------------------LTI-NVQPEDSQQHGTYYC

TEGAGNFDEA--ELTVEVE
.   .  ...  . |..|.
QAT-HGQYWSIQGTTLTVQ
Kinase Spk388.AA STE 80-115 23 0.000359 10.77 In-house 79-124 (359) Show / Hide 
Range on Protein: 80-115
Range on HMM: 79-124/359
Sequence Identity: 23% (11 aa)

VKVLSELLD-QPNVVKCLGYCQ---------EQGSILYEFISGGTL
.|..... .  ||.||..|..          ..  |  |...||.|
IKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSL
Kinase Spk388.AA Tie 82-164 25 0.000427 7.62 In-house 44-135 (267) Show / Hide 
Range on Protein: 82-164
Range on HMM: 44-135/267
Sequence Identity: 25% (24 aa)

VLSELLDQPNVVKCLGYCQEQGSILY---EFISGGTLLTHLQTTGV-QSQPTYGNLKPN------SVRVDEGSLLNLAWQIAKGMQYLASKKL
|.  .   ||..  .| |...| .||   |.   | ||  |    |  . | .   .        .  .    .|. |  .|.|||||. |..
VMCKVGHHPNIINLVGACEHRG-YLYVAIEYAPYGNLLDFLRKSRVIETDPAFAREHTTRFKVNVASTLSSQQILHFAADVARGMQYLSQKQC
Kinase Spk388.AA Pkinase 90-159 17 0.002224 13.03 Pfam 60-124 (293) Show / Hide 
Range on Protein: 90-159
Range on HMM: 60-124/293
Sequence Identity: 17% (14 aa)

PNVVKCLGYCQEQGSIL--YEFISGG----TLLTHLQTTGVQSQPTYGNLKPNSVRV--DEGSLLNLAWQIAKGMQYL
||.|........ ..|    |.  ||     | ....|              .. ..  .|  . . ..||..|..|.
PNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-------------WRHGCFYFSEWECKFYMYQILRGLEYC
Kinase Spk388.AA TK-Unique 489-646 37 1.6e-68 233.92 In-house 1-180 (294) Show / Hide 
Range on Protein: 489-646
Range on HMM: 1-180/294
Sequence Identity: 37% (68 aa)

FTRLGSIGRGDFGGVWKGELR------SNQSHVDVAIRQIPDQVTKSKNVLRAVKILSELPDHPNVVKCLGYCQ---EQGSILYEFISGGTLLTHLQTSG
.. . .||.| || ||.||..      . |..| |  .... . |. .. |.  ....||.||||.|.|||.|.   |.  |..|....|.|...|.|..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-VQSQP-TYGILK------PKNVR---FDEGSLLNLAWQIAKGMQYLAS--KKILHGTLCAHNVLLADRKQCKLSDYGLS
 ...|. |||.||      |. .|    ....|.. |||||.||.||||  ||| |..|||.||||...|.||..|.|..
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMA
Kinase Spk388.AA TK 489-646 17 2.5e-40 132.38 In-house 1-298 (486) Show / Hide 
Range on Protein: 489-646
Range on HMM: 1-298/486
Sequence Identity: 17% (51 aa)

FTRLGSIGRGDFG---GVWKGELRS-----------------------NQSHVDVAIRQIPDQVTKSKNV------------------LRAVKILSE-LP
 | .  .|.| ||    |.|||.|.                       .. ...||. .. .  . |..                   ... |.... | 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DHPNVVKCLGYCQEQG--------------SILYEFISGGT----LLTHLQTSGV---QSQPTYGILKPKNVR---------------------------
.|||.|...|.| ...               |. |. ..|     |...|...     ..|.... ...|...                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------FDEGSLLNLAWQIAKGMQYLASK------KILHGTLCAHNVLLADRKQ-----------CKLSDYGLS
                               ..   ||  .||||.||.||.||      .. |. |.|.|.|......           ||..|.|||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS
Kinase Spk388.AA Pkinase_Tyr 489-646 28 7e-37 125.54 Pfam 1-158 (270) Show / Hide 
Range on Protein: 489-646
Range on HMM: 1-158/270
Sequence Identity: 28% (48 aa)

FTRLGSIGRGDFGGVWKGELR--SNQSHVDVAIRQIPDQVTKS----KNVLRAVKILSELPDHPNVVKCLGYCQ-EQGS----ILYEFISGGTLLTHLQT
 | .  .|.| || |.||...    . ...||.  .... ...    .  .| .||...|..|||.|...| |  ....    |  |.  .| ||..|..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

SGVQSQPTYGILKPKNVRFDEGSLLNLAWQIAKGMQYLASKKILHGTLCAHNVLLADRKQCKLSDYGLS
             . . ...   ||. .|||||||.||.||.. |  |.| |.|... ...| .| ||.
HR-----------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase Spk388.AA TKL 495-646 21 5.5e-29 101.52 In-house 1-201 (364) Show / Hide 
Range on Protein: 495-646
Range on HMM: 1-201/364
Sequence Identity: 21% (47 aa)

IGRGDFGGVWKGELR-------SNQSHVDVAIRQIPDQV-------------------------TKSKNVLRAVKIL-SEL-PDHPNVVKCLGYCQEQG-
||.| || |.||..|       | ..  |||. ... .                          . |..  . .. . . .  .|||.|...|||.. . 
IGSGGFGEVYKGKWRGWGGKCPS-DTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

--------------SILYEFISGGTLLTHLQTSGVQSQPTYGILKPKNVRFDEGSLLNLAWQIAKGMQYLAS--------KKILHGTLCAHNVLLADRKQ
               | .|...||.|| .|.                        ....| .||.||.|| |        ..|.|  |  .|.|. .  .
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWT

--------------CKLSDYGLS
              ||..|.|||
NVSNYMYNPNADWCCKICDFGLS
Kinase Spk388.AA Tie 498-648 26 6.2e-23 66.04 In-house 2-163 (267) Show / Hide 
Range on Protein: 498-648
Range on HMM: 2-163/267
Sequence Identity: 26% (44 aa)

GDFGGVWKGELRSNQSHVDVAIRQIPDQVTKS--KNVLRAVKILSELPDHPNVVKCLGYCQEQGSILY---EFISGGTLLTHLQTSGV-QSQPTYGILKP
| || | |  ..    ...|||... .   .   .     . ..  .  |||..  .| |...| .||   |.   | ||  |  | |  . | . . . 
GNFGQVMKAMIKKDGLKMEVAIKMMKEYASEDDHRDFMGELEVMCKVGHHPNIINLVGACEHRG-YLYVAIEYAPYGNLLDFLRKSRVIETDPAFAREHT

K------NVRFDEGSLLNLAWQIAKGMQYLASKKILHGTLCAHNVLLADRKQCKLSDYGLSSS
               .|. |  .|.|||||. |...|  | | |.| ..   ||..|.||| .
TRFKVNVASTLSSQQILHFAADVARGMQYLSQKQCIHRDLAARNILVCENYVCKIADFGLSRG
Kinase Spk388.AA UTK 489-646 21 3.1e-20 65.95 In-house 1-175 (296) Show / Hide 
Range on Protein: 489-646
Range on HMM: 1-175/296
Sequence Identity: 21% (39 aa)

FTRLGSIGRGDFGGVWKGELRSNQSHVDVAIRQIPDQVTKSKNVLRAVK-------------ILSELPDHPNVVKCLGYCQEQGS--ILYEFISGGTLLT
  ..  .|.| || | |....    |. .... ... . ....  ..               ... .  ||||.. .|.|  ..   |..|. ..| |..
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ-HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRS

HLQTSGVQSQPTYGILKPKNVRFDEGSLLNLAWQIAKGMQYLASKKILHGTLCAHNVLLADR-------KQCKLSDYG---LS
 |.... .         .  . ... ..|  ||.|| |||||.|... |. |.| |.|...         .||..|.|   .|
YLRRHRPTPP-------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMS
Kinase Spk388.AA MLK 489-649 25 4.1e-20 66.57 In-house 1-183 (291) Show / Hide 
Range on Protein: 489-649
Range on HMM: 1-183/291
Sequence Identity: 25% (47 aa)

FTRLGSIGRGDFGGVWKGELRSNQ-SHVDVAIRQIP-------DQVTKSKNVLRAVKILSELPDHPN----VVKCLGYCQEQGS---ILYEFISGGTLLT
.. .  || | || ||||. | .  .   ||....        |  . .... . ...|. | .|||    ... .| |.....   |. |...|| | .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRIL-SHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HLQTSGVQSQPTYGILKPKNVRFDEGSLLNLAWQIAKGMQYLASKK---ILHGTLCAHNVLLAD------RKQCKLSDYGLSSSL
 | .   .. .     |   .. | ....| | |.|.||.|| |..   | |  |  ||.|...       ...| .| |.| ..
VLHGARSKWMDANHNQK-NDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDW
Kinase Spk388.AA Src 489-645 27 2.8e-19 62.12 In-house 1-143 (255) Show / Hide 
Range on Protein: 489-645
Range on HMM: 1-143/255
Sequence Identity: 27% (43 aa)

FTRLGSIGRGDFGGVWKGELRSNQSHVDVAIRQIPDQVTKSKNVLRAVKILSELPDHPNVVKCLGYCQEQ--GSILYEFISGGTLLTHLQTSGVQSQPTY
....  .|.| || ||.|  . |   ..||.  .     . .  |.  .|. .| .|...|. .  | .     |  |. | | ||. |.          
IKLCRKLGQGQFGEVWMGYWNGN---TKVAVKTLKPGTMSPEAFLQEAQIMKKL-RHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK---------

GILKPKNVRFDEGSLLNLAWQIAKGMQYLASKKILHGTLCAHNVLLADRKQCKLSDYGL
   ...  .     |. .|.|.|.||.|| |... |  | | |||  .   ||  | ||
---DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGL
Kinase Spk388.AA TKL-Unique 491-649 26 3.4e-19 64.48 In-house 1-167 (290) Show / Hide 
Range on Protein: 491-649
Range on HMM: 1-167/290
Sequence Identity: 26% (46 aa)

RLGSIGRGDFGGVWKGELRSNQSHVDVAIRQIP---DQV-TKSKNVLRAVKILSELPDHPNVVKCLGYCQ----EQG--SILYEFISGGTLLTHLQTSGV
 . .||.| .| | ||. |.     .||| |.    |.  .....  . |.... |  |||.|.. |||      ..  .|  |...||.|  .|...  
FWNKIGEGGYGQVYKGKWRGY----PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNN

QSQPTYGILKPKNVRFDEGSLLNLAWQIAKGMQYLASKK--ILHGTLCAHNVLLADR-----KQCKLSDYGLSSSL
 .        ..|  ..    ...| .||.|| || ...  |.|..|   |.|.  .      . |..| ||| ..
NNN-----NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFN
Kinase Spk388.AA STE 489-649 23 4.1e-19 64.22 In-house 1-197 (359) Show / Hide 
Range on Protein: 489-649
Range on HMM: 1-197/359
Sequence Identity: 23% (49 aa)

FTRLGSIGRGDFGGVWKG--------ELRSNQS------HVDVAIRQIP------------------DQVTKSKNVLRAVKILSELPD-HPNVVKCLGYC
..... ||.| || | |.        . ....       .. .|| |..                  .. .. ...|. .||.... . |||.||..|..
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

Q---------EQGSILYEFISGGTLLTHLQTSGVQSQPTYGILKPKN------VRFDEGSLLNLAWQIAKG-MQYLASKKILHGTLCAHNVLLADRKQCK
          ..  |  |...||.|   ...       .||..|| |       ||.|  .   . || || ..|| |..| |  . . |.||     .|
FKEGHNHKNDDELWICMEYMDGGSLDDIIKH-------KYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VK

LSDYGLSSSL
|.| |....|
LCDFGVCGQL
Kinase Spk388.AA Pkinase 489-646 23 6.3e-19 68.0 Pfam 1-159 (293) Show / Hide 
Range on Protein: 489-646
Range on HMM: 1-159/293
Sequence Identity: 23% (41 aa)

FTRLGSIGRGDFGGVWKGELRSNQSHVDVAIRQIPDQVTKSKN---VLR--AVKILSELPDHPNVVKCLGYCQEQGSIL--YEFISGG----TLLTHLQT
..... ||.| || |.|.  ....    ||. .|. . .||.     .|   ..|. .| .|||.|........ ..|    |.  ||     | ....|
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

SGVQSQPTYGILKPKNVRF--DEGSLLNLAWQIAKGMQYLASKKILHGTLCAHNVLLADRKQC----KLSDYGLS
              .. .|  .|  . . ..||..|..|. |..|.|  |   |.|. .. ..    |..| ||.
-------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase Spk388.AA Ciliate-E2 489-646 18 2.4e-17 56.08 In-house 1-203 (365) Show / Hide 
Range on Protein: 489-646
Range on HMM: 1-203/365
Sequence Identity: 18% (41 aa)

FTRLGSIGRGDFGGVWKGELRSNQSHV----------------------DVAIRQIPDQVTKSKNVLRAVK-------------ILSELPDHPNVVKCLG
.  .  ||.| || |.|.. ...|  .                          .....|.   |....  .             ||..| .|||..|.  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQL-NHPNIIKMYE

YCQEQGS----ILYEFISGGTLLTHLQ---TSGVQSQPTYGILKPKNVRFDEGSLLNLAWQIAK---------------GMQYLASKK-ILHGTLCAHNV
. ||.      .  |...||.|. ...   ..  . ..     | .  .|.|   ... .||..               ...|| ||. |.|  .   |.
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE-----K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENI

LLADRKQCKLSDYGLS
|.     .|..| |||
LF-----IKIIDFGLS
Kinase Spk388.AA TyrKc 489-662 17 6.7e-11 -46.45 SMART 1-280 (280) Show / Hide 
Range on Protein: 489-662
Range on HMM: 1-280/280
Sequence Identity: 17% (52 aa)

FTRLGSIGRGDFGGVWKGELRSNQSHVDVAIRQIPDQVTKSKNVLRAVKILSEL-PDHPNVVKCLGYCQ---------EQGSILYEFISGGTLLTHLQTS
 | .  .|.| || |.||...     ..||.  . .     .  .|  .|...| ..|||.|...|.|          |.  |. |. ..| |. .|. .
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

GVQSQPTYGILKPKNVRFDEGSLLNLAWQIAKGMQYLASKKILHGTLCAHNVLLADRKQCKLSDYGLSSSLF------------------SGR-------
. .              .    ||. .||||.||.||.||.. |  | | |.|.......| || |||  .                   .|.       
RPK--------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

------------------------------------G-------------------------V-------------------------------SIIAFI
                                    |                                                         | |  .
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

L
.
F
Kinase Spk388.AA S_TKc 489-664 17 2.3e-08 -54.16 SMART 1-231 (231) Show / Hide 
Range on Protein: 489-664
Range on HMM: 1-231/231
Sequence Identity: 17% (45 aa)

FTRLGSIGRGDFGGVWKGELRSNQSHVDVAIRQIPDQVTKSKNVLRAVKILSELPDHPNVVKCLGYCQ-EQGSILYEFISG--GTLLTHLQTSGVQSQPT
.. |  ||.| || |.|.  ..  ..  ||| .|.      ....| ..||..  .|||.||.....| .   .  |...|  |.|.....  | .    
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRH----

YGILKPKNVRFDEGSLLNLAWQIAKGMQYLASKKILHGTLCAHNVLLADRKQCKLSDYGLSSSL----------------FSG-----------------
     .....|.|     ...||.....|. |..|.|  |   |.|| .  . |..| ||.  |                ...                 
-----GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLC

------------------RGVSIIAFILM-----------------------I
                   . ..|  .|                        .
GYPPFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF