Gene KSR2 (Sea Urchin)
KSR2
Sequence
Protein domains of KSR2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| C1 | KSR2.AA | C1 | 24-70 | 19 | 4e-06 | 27.46 | SMART | 1-61 (61) | Show / Hide |
Range on Protein: 24-70 Range on HMM: 1-61/61 Sequence Identity: 19% (12 aa) HCYTRQLVSPAKRCDFCKKSMFVM--------TLRCKDCRVRCHRRCAQQAAN-------LC | . .. . ..|. |.|... | .|| .|...|| .|. .... | HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC |
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| C1_1 | KSR2.AA | C1_1 | 35-73 | 20 | 3.7e-05 | 22.59 | Pfam | 13-55 (55) | Show / Hide |
Range on Protein: 35-73 Range on HMM: 13-55/55 Sequence Identity: 20% (9 aa) KRCDFCKKSM----FVMTLRCKDCRVRCHRRCAQQAANLCELA ..|. |.... . . ..| .| ..|| ||.......| . TFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN |
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| Kinase | KSR2.AA | KSR | 317-574 | 48 | 2.2e-185 | 622.16 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 317-574 Range on HMM: 1-272/272 Sequence Identity: 48% (131 aa) LKYGRCIEKGKLGSTYKGHWHGEVLIQTRYSK-----STDINDFLDEVAMLSKIRHENIALFMGACVEPGNLAVVNSIHKG-PSLYHHLHVQRRKLQTSS ||||.||..|..|....|||||||.|...|.. ..|..||.|||.|....|||||.||||||..|..||.|.|..|| ..||||.||.|.||.... LKYGECIGQGRFGKVHRGHWHGEVAIKLYYMDHIHDEHHDLEDFKDEVMMYKNTRHENIVLFMGACMNPPHLAIVMSLCKGSQTLYHHIHVRREKLDMNR KMDIARQIGQAMGYLQAKGIIVGHLSSRCVYLESKVKLSVTRVDTSDVT-----CQRASHACLPRGKLQYLAPELLAKARVVPPEFITG-NEQTHSTDVY .|.||.||.|.||||.|||||...|.|.....|.|.|...|.......| |||..|.|.|.|.|.||||||....|....|.... ....|..||| TMQIAQQICQGMGYLHAKGIIHKDLKSKNIFYENKGKVVITDFGLFSITRLLHCCQREDHLCIPHGWLCYLAPELIRAMRPNYDEYQCMCLPFSHHSDVY AFGTILFEIIAGRWPLQYACSESVIYQTCSG--RRDDFRNVTCSSTMKNLIQECWSQNPNERPSFQDIVKEL |||||..|.|.|.||..|.|.||.|.|.|.| .|...|||.|...||.....|||..|.|||.||||.|.| AFGTIWYEMICGEWPFKYQCAESIIWQMCQGEGMRQVLRNVQCGREMKEILMMCWSYEPQERPTFQDIMKML |
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| Kinase | KSR2.AA | RAF | 317-574 | 37 | 6.2e-154 | 517.69 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 317-574 Range on HMM: 1-275/275 Sequence Identity: 37% (104 aa) LKYGRCIEKGKLGSTYKGHWHGEVLIQTRYSKS----TDINDFLDEVAMLSKIRHENIALFMGACVEP--GNLAVVNSIHKGPSLYHHLHVQRR-KLQTS ...|..|..|..|..|.|||||.|...|...|. .....|..||.|..|.|||||.||||.|..| ...|.|....||..||||.|||.. |.... VQIGERIGQGRFGTVYRGHWHGDVAVKTLNMKYPTPEHQLQAFKNEVMMYKKTRHENIVLFMGYCMKPDNPHYAIVTQWCKGSTLYHHIHVQKTEKFDMN SKMDIARQIGQAMGYLQAKGIIVGHLSSRCVYLESKVKLSVTRVDTSDVT-CQRA----SHACLPRGKLQYLAPELLAKARVVPPEFI-TGNEQTHSTDV ....||.||.|.|.||.||.||...|.|....|........|......|. |... ...|.|.|.....|||.....|....|.. ..|......|| WTIQIAQQICQGMDYLHAKNIIHRDLKSKNIFLHNGKVVVITDFGLFTVKRCRWCKRRKQQLCQPHGWICWMAPEVIRMMRPDWDEYQCDCNPFSFQSDV YAFGTILFEIIAGRWPLQYACS-ESVIYQTCSGRRDDFRN---VTCSSTMKNLIQECWSQNPNERPSFQDIVKEL |||||...|..||.||.|.... |..|...|.|.....|. |.|...||.|..||||..|.||||||.|.|.. YAFGTVWYELMAGEWPYQHIQWHEQIIWMVCRGYLRMDRSKARVQCPKEMKELLMECWSYQPEERPSFQQIMKMI |
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| Kinase | KSR2.AA | TKL | 323-574 | 21 | 9.3e-58 | 198.2 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 323-574
Range on HMM: 1-364/364
Sequence Identity: 21% (79 aa)
IEKGKLGSTYKGHWHG-----------EVLIQTRYSKSTD---------------------------INDFLDEVA-MLSKIRHENIALFMGACVEPGN-
| .| | |||.|.| .| . . |.. | ...|. |.. |.|..||.|| .|||.| .|..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
------------LAVVNSIHKGPSLYHHLHVQRRKLQTSSKMDIARQIGQAMGYLQA--------KGIIVGHLSSRCVYLESK----------------V
|. | ..| ||.|.|| . ....|..| ..| || . ..|| | |. . . .. .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC
KLS----VTRVDTS-DVTC------------QRASHACLPRGKLQYLAPELLAKARVVP------PEFITGNEQTHSTDVYAFGTILFEIIAGRWPLQ-Y
|.. .....| . .. ..... . ..| ....|||.| .. . . |. | | . ..|||.|| .|.||.....| . |
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY
ACS--------ESVIYQTCSGRRDDFRN------------VTCSSTMKNLIQECWSQNPNERPSFQDIVKEL
.. | ... |. .. . .| ||.|.|.||...|..|||||.|.|.|
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | KSR2.AA | RAF | 317-576 | 27 | 2.9e-50 | 161.03 | In-house | 1-282 (282) | Show / Hide |
Range on Protein: 317-576 Range on HMM: 1-282/282 Sequence Identity: 27% (78 aa) LKYGRCIEKGKLGSTYKGHWHGEVLIQT---RYSKSTDIND---FLDEVAMLSKIRHENIALFMGACVEPG--NLAVVNSIHKGPSLYHHLHVQRR--KL .. . | |. |. |.|||||.| ... . .. | .|||.. | || ||.|||| .| .|.| . |||||.||| |. VMVMTRIGSGSFGTVYRGHWHGDVAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILLFMGYMSKPQTNTYAIVTQWCEHSSLYHHIHVQETREKF QTSSKMDIARQIGQAMGYLQAKGIIVGHLSSRCVYLESKVKLSVTRVDTSDVTCQRA----SHACLPRGKLQYLAPELLA------KARVVPPEFITGNE . . .||.||. |.| || || || | |. ..|. .. .. | . . | . ..||| . |. . | DMHWLIDISRQVCQGMDYLHAKNIIHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVL---MQDENP QTHSTDVYAFGTILFEIIAGRWPL--QYACSESVIY----QTCSGRRDDFRNVTCSSTMKNLIQECWSQNPNERPSFQDIVKELKK . |||.||....|..... | . . . .|. . ... |. | |. |...||. ...|||.|| |.|... YSFQSDVYSFGIVMYELMTRHMPYGCHIWNRDQIIFMCGRGYLRPDLSKVRQ-DCPKAMHRLMEDCWKFQREERPLFQQILKRITV |
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| Kinase | KSR2.AA | TKL-Unique | 487-574 | 26 | 8.4e-15 | 48.78 | In-house | 193-290 (290) | Show / Hide |
Range on Protein: 487-574 Range on HMM: 193-290/290 Sequence Identity: 26% (26 aa) VPPEFITG--NEQTHSTDVYAFGTILFEIIAGRW------PLQYACSESVIYQTCSGRRDDFRNVT---CSSTMKNLIQECWSQNPNERPSFQDIVKEL ..|| ... . . . |||.||..| ||. . | | ... .... . . .| | ..|||.|| ..| .||||..|...| MAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQ-GMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL |
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| Kinase | KSR2.AA | TK | 488-574 | 18 | 7.1e-14 | 42.14 | In-house | 353-486 (486) | Show / Hide |
Range on Protein: 488-574
Range on HMM: 353-486/486
Sequence Identity: 18% (25 aa)
PPEFITGNE---------QTHSTDVYAFGTILFEIIA-GRWPLQYACS----------ESVIYQTCSG-------------RRDDFRNVTCS--------
.|| ..... |. .||..|| ..|| |. | | . |. . ..| | . . |.
APECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMH
------STMKNLIQECWSQNPNERPSFQDIVKEL
. |.|.||. .|..||.|......|
PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| Kinase | KSR2.AA | MLK | 544-574 | 48 | 7.7e-14 | 44.51 | In-house | 261-291 (291) | Show / Hide |
Range on Protein: 544-574 Range on HMM: 261-291/291 Sequence Identity: 48% (15 aa) TCSSTMKNLIQECWSQNPNERPSFQDIVKEL ||. .|.|...||.|.|..||||. ||..| TCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL |
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| Kinase | KSR2.AA | Pkinase | 475-574 | 18 | 1.5e-13 | 48.95 | Pfam | 177-293 (293) | Show / Hide |
Range on Protein: 475-574 Range on HMM: 177-293/293 Sequence Identity: 18% (23 aa) YLAPELLAKARVVPPEFITGNEQTHSTDVYAFGTILFEIIAGRWPLQYA------CSESVIYQTCSGRRDDFRNVTCS-------------------STM |.|||.. .|.. ... |....| ||.| . || | . . . .|... ... . . .|| ... YMAPEVIR----------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC KNLIQECWSQNPNERPSFQDIVKE--L | .| |. ..|..||....|.. . KDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | KSR2.AA | TKL-Unique | 319-449 | 26 | 2.3e-13 | 43.68 | In-house | 1-159 (290) | Show / Hide |
Range on Protein: 319-449 Range on HMM: 1-159/290 Sequence Identity: 26% (42 aa) YGRCIEKGKLGSTYKGHWHGEV--LIQTRY-SKSTDI--NDFLDEVAMLSKIR-HENIALFMGACV----EPGNLAVVNSIHKGPSLYHHLH-------- . | |. |. ||| |.|. ..| ..| . .| .|| ..|.. |.|| ..||.|. |.|. | . | ||| .|| FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN -VQRRKLQTSSKMDIARQIGQAMGYLQAKG--IIVGHLSSRCVYLESK-------VKLS . || . ....|..| |.| || .. || . | |. ... .. .|.. NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKIC |
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| Kinase | KSR2.AA | TyrKc | 317-574 | 23 | 6.3e-13 | -13.62 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 317-574
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)
LKYGRCIEKGKLGSTYKGHWHGEVLI-QTRYSKSTDINDFLDEVAMLSKI--RHENIALFMGACVEP-------GNLAVVNSIHKGPSLYHHLHVQRRKL
.. |. . | | |||.| .| . . .. . ||..| ...|. .|.|| . |.|... . | .| .. .| ..|. |.||
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL
QTSSKMDIARQIGQAMGYLQAKGIIVGH--LSSR-CVYLESK-VK-----LSVTRVDT------SDVTCQR---ASHACLPRGKLQYLAPELLAKARVVP
... . ... || . | || |..| | | | | . | . || || | .|. .. ... || . .||| .
CMKDLLSFCWQIACGMEYLHSKNCI--HRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP---IRWMAPECI-------
PEFITGNEQTHSTDVYAFGTILFEIIA-GRWPLQY-----ACSESVIYQTCSGRRDDFRNV-------TCSSTMKNLIQECWSQNPNERPSFQDIVKEL
.. |. .||..|| ..|| | | . || . .|.| . .|.. | .....|| .|..||.|..|....
----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
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| Kinase | KSR2.AA | S_TKc | 317-580 | 17 | 9.5e-13 | 10.07 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 317-580
Range on HMM: 1-231/231
Sequence Identity: 17% (49 aa)
LKYGRCIEKGKLGSTYKGHWHGEVLIQTRYSKSTDINDFLDEVAMLSKIRHENIALFMGACVEPGNLAVVNSIHKG--PSLYHHLHVQRRK-----LQTS
. .| | || |. ||..... . | . .... |...|.| .|.|| . ..... ..| .| | .|..... ..|. .
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK-EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-
SKMDIARQIGQAMGYLQAKGII----------VGHLSSRCVYLESKVKLS---VTRVDTSDVTCQRASHACLPRGKLQYLAPELLAKARVVPPEFITGNE
...|| .|. |. .||| . . .|.. . |. | . |.|||.|
HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----------HIKICDFGLARQL------------TTFCGTPWYMAPEVL--------------G
QTH-STDVYAFGTILFEIIAGRWPLQYACSESVIYQTCSGRRDDFRNVTCSSTMKNLIQECWSQNPNERPSFQDIVK---ELKKNVSL
.. . |....| ||.| ..|. | . . .... . |. .|..|. |. .|..||. .. . . |. .
YGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | KSR2.AA | Pkinase_Tyr | 488-574 | 28 | 4.2e-12 | 41.62 | Pfam | 182-270 (270) | Show / Hide |
Range on Protein: 488-574 Range on HMM: 182-270/270 Sequence Identity: 28% (26 aa) PPEFITGNEQTHSTDVYAFGTILFEIIA-GRWP-LQYACSESVIYQT-CSGRRDDFRNVTCSSTMKNLIQECWSQNPNERPSFQDIVKEL .|| | .. |. .||..|| ..||. |. | . | |. . .|.| . |. . .|...|| ..|..||.|..|. .| APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC-PENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | KSR2.AA | MLK | 317-425 | 23 | 6.8e-12 | 37.67 | In-house | 1-140 (291) | Show / Hide |
Range on Protein: 317-425 Range on HMM: 1-140/291 Sequence Identity: 23% (33 aa) LKYGRCIEKGKLGSTYKGHWHGEV-----LIQTRYS--------KSTDINDFLDEVAMLSKIRHEN----IALFMGACVEPGN-LAVVNSIHKGPSLYHH .. . | .| |. .|| |... . |. ... . || |. |....|.| | |.|.| .|.. ...| | |||. IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV LHVQR-------------RKLQTSSKMDIARQIGQAMGYL || .| | ...|..| |. ..| || LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYL |
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| Kinase | KSR2.AA | Dicty4 | 545-576 | 41 | 1.1e-11 | 35.39 | In-house | 244-277 (277) | Show / Hide |
Range on Protein: 545-576 Range on HMM: 244-277/277 Sequence Identity: 41% (14 aa) CSSTMKNLIQECWSQNPNERPSFQDIVKE--LKK |. | |||.||. .|. ||||. |... | CPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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| Kinase | KSR2.AA | Frk | 317-440 | 24 | 3.6e-11 | 34.61 | In-house | 1-129 (260) | Show / Hide |
Range on Protein: 317-440 Range on HMM: 1-129/260 Sequence Identity: 24% (32 aa) LKYGRCIEKGKLGSTYKGHWHGE--VLIQTRYSKSTDINDFLDEVAMLSKIRHENIALFMGACVEPGNLAVVNSIHKGPSLYHHLH---VQRRKLQTSSK ... | . |..| . | | . | ..| . . | |||| | .. |.|| . | . .. . . || ..| . |..| IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL MDIARQIGQAMGYLQAKGIIVGHLSSRCV .|.| |. | || . | | | | VDMAAQVAAGMAYLESQNYIHRDLAARNV |
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| Kinase | KSR2.AA | Dicty4 | 317-386 | 35 | 1.1e-10 | 32.02 | In-house | 1-80 (277) | Show / Hide |
Range on Protein: 317-386 Range on HMM: 1-80/277 Sequence Identity: 35% (29 aa) LKYGRCIEKGKLGSTYKGHWHGE-----VL--IQTRYSKSTDINDFLDEVAMLSKIRHENIALFMGACV----EPGNLAVV .. . | || .|. ||| | | .| .. . .. .|.|. ||. ..|||| || |||||| .|| . | INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENM-LNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIV |
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| Kinase | KSR2.AA | TK | 317-438 | 12 | 1.2e-10 | 31.09 | In-house | 1-269 (486) | Show / Hide |
Range on Protein: 317-438
Range on HMM: 1-269/486
Sequence Identity: 12% (33 aa)
LKYGRCIEKGKLG---STYKGHWHG----------------------------EVLIQTRYSK-STDINDFLD--------------EVAMLSKIR----
...|. . .| | ||| |.| .| . . .. ... ..|.| |...... .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
-HENIALFMGACVEPG-------------NLAVVNSIHKGP---SLYHHLHVQRRK--------------------------------------------
|.|| . |.|.... . |. ..| || ..|. |.|
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
-------------------------------LQTSSKMDIARQIGQAMGYLQAK------GIIVGHLSSR
| . .. ...|| ..| || .| ... . | |
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAAR
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| Kinase | KSR2.AA | Pkinase_Tyr | 351-431 | 24 | 2.3e-10 | 35.74 | Pfam | 44-133 (270) | Show / Hide |
Range on Protein: 351-431 Range on HMM: 44-133/270 Sequence Identity: 24% (22 aa) D--INDFLDEVAMLSKI-RHENIALFMGACV---EP-GNLAVVNSIHKGPSLYHHLHVQ---RRKLQTSSKMDIARQIGQAMGYLQAKGII . . ||. |....... .|.|| ..|.|. || . |. .| .|...|. . ...| .. . ....|| ..| || .|..| QNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG-DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCI |
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| Kinase | KSR2.AA | CZAK | 317-383 | 35 | 2.5e-09 | 30.17 | In-house | 1-76 (279) | Show / Hide |
Range on Protein: 317-383 Range on HMM: 1-76/279 Sequence Identity: 35% (27 aa) LKYGRCIEKGKLGSTYKGHWHGEV-------LIQTRYSKST-DINDFLDEVAMLSKIRHENIALFMGACVEPG-NL || |. | .| | ||. | | . ..| | .. . | |. ||. .|| .| |. |.||| | | |. LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNH |
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| Kinase | KSR2.AA | Frk | 489-578 | 29 | 5e-09 | 27.05 | In-house | 171-260 (260) | Show / Hide |
Range on Protein: 489-578 Range on HMM: 171-260/260 Sequence Identity: 29% (27 aa) PEFITGNEQTHSTDVYAFGTILFEIIA-GRWPLQYACSESVIYQTCSGRRDDFRNVTCSSTMKNLIQECWSQNPNERPSFQDIVKELKKNV || . |. | ||..|| .| ||| || | |. . | | . | .. ....||| ..|..|| | . |.. PEAANYNKFTIKSDVWSFGILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMP-QPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF |
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| Kinase | KSR2.AA | CZAK | 542-574 | 38 | 1e-07 | 24.25 | In-house | 244-279 (279) | Show / Hide |
Range on Protein: 542-574 Range on HMM: 244-279/279 Sequence Identity: 38% (14 aa) NVTCSSTMK---NLIQECWSQNPNERPSFQDIVKEL . . .. | || || || ||||| |. | PQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL |
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| Kinase | KSR2.AA | Pkinase | 317-431 | 17 | 1.9e-07 | 27.42 | Pfam | 1-130 (293) | Show / Hide |
Range on Protein: 317-431 Range on HMM: 1-130/293 Sequence Identity: 17% (23 aa) LKYGRCIEKGKLGSTYKGHWHGE-------VLIQTRYSKSTDINDFL-DEVAMLSKIRHENIALFMGACVEPGNLAVVNSIHKGP----SLYHHLH-VQR .. ||.| .| |. ||.|..|. .. . ... |..... |.... ...|.|| . ... ..... .| . | .|..... .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH RKL--QTSSKMDIARQIGQAMGYLQAKGII ... . ....|| ... |. ..||| GCFYFSEWECKFYMYQILRGLEYCHSMGII |
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| Kinase | KSR2.AA | CZAK | 489-521 | 45 | 0.000411 | 11.01 | In-house | 191-223 (279) | Show / Hide |
Range on Protein: 489-521 Range on HMM: 191-223/279 Sequence Identity: 45% (15 aa) PEFITGNEQTHSTDVYAFGTILFEIIAGRWPLQ || | | ||| || ||..|| .. | | PECFKGENYTEKVDVYSFGMILWCIITCDQPYQ |
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| Kinase | KSR2.AA | Dicty4 | 489-513 | 40 | 0.295842 | 0.14 | In-house | 186-210 (277) | Show / Hide |
Range on Protein: 489-513 Range on HMM: 186-210/277 Sequence Identity: 40% (10 aa) PEFITGNEQTHSTDVYAFGTILFEI || ... . . ||| || .|.|| PEVMMHQPYNEKADVYSFGIVLWEI |
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