Gene TKL6 (Sea Urchin)

TKL6

Species: Sea Urchin
Alias: TKL6, SpTKL1d, SPU_016455, Spk311
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TKL
Family: TKL-Sp1

Sequence

Name Sequence Type Origin Length Description Download
TKL6.AA Protein None 385 None Fasta, JSON
TKL6.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of TKL6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TKL6.AA TKL-Sp1 120-377 56 4.3e-213 673.41 In-house 1-263 (263) Show / Hide 
Range on Protein: 120-377
Range on HMM: 1-263/263
Sequence Identity: 56% (149 aa)

LNLGETVGRGAFGEVKKAVWRGTTVAVKIISTAGSKKDEVEKEVSIHKRARHPNIVSLMAVGHRIGQVLIVMEFIDGMNLHDVIFRKKD--GITLTPELK
|..|..||.|.||.|..|.||||.||||.||..||.|||.||||.||.||.|||||..||.|........||.||.|..||.|||...|  .|.|....|
LDMGPVVGKGQFGVVHRASWRGTPVAVKKISMMGSRKDEIEKEVAIHRRACHPNIVQMMALGYQGKEAFLVMQFIEGPSLHTVIFPDRDDVKIPLDWAKK

MSITVGLLSALTFLHASKILHLDIKPSNVMVERASRRAYLCDLGLAHIKTRSSMSLSTSLRGPRGTITHFAPEMVQKQGKAWAGP-GNDIWSIACTFLEL
|.|....|.|.||.||..||||||||.|||||||.||.|.|||||||||.|..||.|||....|||..|..|||||||...|..| ..||||.||||.||
MQISCEVLQAVTFMHACNILHLDIKPANVMVERATRRPYICDLGLAHIKNRNHMSQSTSMVNMRGTPCHMPPEMVQKQEPGWRHPNKHDIWSVACTFVEL

FVEQTLWEG-VEFLKLLRTLLK-PDAVPPILKKVKPEVRTILKPCFDKEPLKRPSAEVLLGQF
.....||.. .||..|.|..|. ....|.||.||.|.|..||.||||..|.||||||.||.||
YSMKRLWGDSMEFMALMRRILTGQMSKPEILTKVDPKVQKILEPCFDQKPEKRPSAEDLLDQF
Kinase TKL6.AA TKL 126-377 17 4.8e-53 182.55 In-house 1-364 (364) Show / Hide 
Range on Protein: 126-377
Range on HMM: 1-364/364
Sequence Identity: 17% (64 aa)

VGRGAFGEVKKAVWRG----------TTVAVKIISTAGSKK----------------------------DEVEKEVSIHKRARHPNIVSLMAVGHRIGQ-
.|.|.|||| |..|||          ..||||....  ...                            .. |.|. ...| ||||||..|..  .... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VLIVMEFIDGMNLHDVIFRKKDGITLTPELKMSITVGLLSALTFLHASK--------ILHLDIKPSNVMVERASR-------------
              ||||...| .|....          .......  .  ... .||...        |.| |.|..|..| .  .             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

RAYLCDLGLAHIKTRSSMSLSTS---------------LRGPRGTITHFAPEMVQKQG----KA---------WAGPGNDIWSIACTFLELFVEQTLWEG
.. .||.||.  ...|. .  |.               .  ..||. . |||. ..|.    |.          . .  |..| .  . |..  .. ...
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

VEFL------------KLLRTLLKPDAVP---------PILKKVKPEVRTILKPCFDKEPLKRPSAEVLLGQF
  .             ..     ..  .|         .  . . |... ... | | .| ||||.. .| ..
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase TKL6.AA S_TKc 120-379 23 5.2e-51 176.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 120-379
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

LNLGETVGRGAFGEVKKAVWRG--TTVAVKIISTAGSKKDEVEKEVSIHKRARHPNIVSLMAVGHRIGQVLIVMEFIDG--MNLHDVIFRKKDG---ITL
  .....|.||||.|.|.....    ||.|||.      . ...|..|.|. .||||| |  | .  . . .|||..||   .|.|.| ... .     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TPELKMSITVGLLSALTFLHASKILHLDIKPSNVMVERASRRAYLCDLGLAHIKTRSSMSLSTSLRGPRGTITHFAPEMVQKQGKAWAGPGNDIWSIACT
..    ...  ...|| ..|  .|.| |.||.|... .   .  .|| ||| .            .   ||    |||..      . ..  |.||. |.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-----------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCI

FLELFVEQTLWEGVEFLKLLRTLLKPDAVPPILKKVKPEVRTILKPCFDKEPLKRPSAEVLLG-------QFQK
. |... .....  .  .... ..             ||.. ... |..|.| |||.|  .|            
LYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TKL6.AA Pkinase 120-377 24 2.4e-47 168.39 Pfam 1-293 (293) Show / Hide 
Range on Protein: 120-377
Range on HMM: 1-293/293
Sequence Identity: 24% (74 aa)

LNLGETVGRGAFGEVKKAVWRGTT--VAVKIISTAGSKKDEVEK-----EVSIHKRARHPNIVSLMAVGHRIGQVLIVMEFIDGM----NLHDVIF-RKK
. .|...|.|.||.|.|....||   ||||||.  . |... .      |..|.|| .||||| |  . .. . . .|||. .|      |.|.|  ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DGITLTPELKMSITVGLLSALTFLHASKILHLDIKPSNVMVERASRRA---YLCDLGLAHIKTRSSMSLSTSLRGPRGTITHFAPEMVQKQGKAWAGPGN
 .......   ..   .|..| ..|. .|.| |.||.|... .    .    .|| |||  .       .. . .. ||.   ||| ..  |    ||  
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR--GGQYYGPKV

DIWSIACTFLELFVEQTLWEGV------EFLKLLRTLLKPDAVPPILKKVK-------------------PEVRTILKPCFDKEPLKRPSAEVLLGQ--F
|.||. |.. |..  .... |       . .....  ..|.   .. ..                     .| . ..| |..| | |||.|| .|    |
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase TKL6.AA STE 120-374 22 1.6e-43 150.9 In-house 1-352 (359) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-352/359
Sequence Identity: 22% (82 aa)

LNLGETVGRGAFGEVKKAVWR-----------------GTTVAVKIISTAG------------------SKKDEVEKEVSIHKRAR--HPNIVSLMAVGH
. . | .|.||||.| ||. .                 |. .|.|...                     .......||..|.|. .  |||||       
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

RIG-------QVLIVMEFIDGMNLHDVIFRK-KDGITLT---------PELKM-SITVGLLSA-LTFLHASKILHLDIKPSNVMVERASRRAYLCDLGLA
. |       .. |.||..||  | |.| .| . | .|.         ||     |.. .| . | .||  .| | ||||.|...      . ||| |..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

HIKTRSSM------------SLSTSLRGPRGTITHFAPEMVQKQG---KAWAGPGNDIWSIACTFLELFVEQTLWEGVEFLKLLRTLLKP----------
 . | |.             . .       ||  . |||..|..|   .   .   ||||. || .|.   .  |     .. .   ..           
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----DAVPPILK-------------------KVKPEVRTILKPCFDKEPLKRPSAEVLL
    .  ||.                     |. || .  .. |..|.| |||.|. ||
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLL
Kinase TKL6.AA CAMK 125-309 17 1.6e-38 121.29 In-house 1-320 (425) Show / Hide 
Range on Protein: 125-309
Range on HMM: 1-320/425
Sequence Identity: 17% (55 aa)

TVGRGAFGEVKKAVWRGTT--------------VAVKIISTA-----------------------------GSKKDEVEKEVSIHKR-------ARHPNI
| |||.||.||... . ||              ||.|||..                              ......|..|..|.|.        .||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLMAVGH------------RIGQ--------VLIVM---EFIDGM----NLHDVIFRKKDG------------ITLTPELKMSITVGLLSALTFLHASK
..|  |                 .        . .||   |...|      | | | .....              .| .    .   ..||. ..|  .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ILHLDIKPSNVMVERAS----------------RRAYLCDLGLAHIKTRSSMSL-------------------STSLRGPRGTITHFA-PEMVQK-QGKA
| |.|.|| |...   .                    ..| |.| ...... ..                      .. . ||    | ||.... ....
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

W----------AGPGNDIWSI
.           ||  |.||.
MQNATDEEKPYYGPKCDMWSC
Kinase TKL6.AA TKL-Unique 122-291 24 3.2e-34 118.14 In-house 1-197 (290) Show / Hide 
Range on Protein: 122-291
Range on HMM: 1-197/290
Sequence Identity: 24% (48 aa)

LGETVGRGAFGEVKKAVWRGTTVAVKIIST-AGSKKDEVE---KEVSIHKRAR-HPNIVSLMAVGH----RIGQVLIVMEFIDGMNLHDVIFR-------
 ....|.|..|.|.|..|||. ||.|...  ..| .....   .||.. |. . ||||| .|.. .     ...  ||||...| .|.||. .       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

KKDGITLTPELKMSITVGLLSALTFLHASK--ILHLDIKPSNVMVERAS----RRAYLCDLGLAHIKTRSSMSLSTSL-----RGPRGTITHFAPEM
 .. ..|........     ... .|| ..  |.|.|.|.||. | ..|     .. .|| ||. ...... . .. .      .. |..   |||.
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV
Kinase TKL6.AA MLK 120-272 20 2.2e-30 102.7 In-house 1-192 (291) Show / Hide 
Range on Protein: 120-272
Range on HMM: 1-192/291
Sequence Identity: 20% (40 aa)

LNLGETVGRGAFGEVKKAVWRGTT-----VAVKIIS-------TAGSKKDEVEKEVSIHKRARHPN----IVSLMAVGHRIGQ-VLIVMEFIDGMNLHDV
... | .| |.||.| |..||...     ||||..         ... ....|.|. . .. .|||    |. ...| .. .. ..||||...|  |..|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

IFRKKDGIT-----------LTPELKMSITVGLLSALTFLHASK---ILHLDIKPSNVMVER-----ASRRAYLCDLGLAHIKTRS---SMS
.  .....             .....|.. .   ... .||. .   | | |.|..|... .     . . .  || |... ....    ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMS
Kinase TKL6.AA MOS 120-248 30 5e-27 86.49 In-house 1-147 (299) Show / Hide 
Range on Protein: 120-248
Range on HMM: 1-147/299
Sequence Identity: 30% (46 aa)

LNLGETVGRGAFGEVKKAVWRGTTVAVKIIS----TAGSKKDEVEKEVSIHKRARHPNIVSLMAVG--HRIGQV---LIVMEFIDGMNLHDVIFRKKDGI
  | .  |||.||.| || ..|. ||||..      .   .     || .  |.||.||| .|||.     .     .|.||.  . .|| ||    .. 
VCLCQMIGRGGFGSVWKAQYCGRPVAVKQVNKCTKNLKAMRRSFWAEVNY-LRLRHDNIVRVMAVSQRSPEDFNNLGTIIMECGGNQTLHQVI----YEP

TLTPE--------------LKMSITVGLLSALTFLHASKILHLDIKPSNVMV
|. |.                . ..   ..||...|. .|||||.|| |..|
TRHPPGDAGIIHCRMLILMHCCKYSLDVVNALQYCHHQNILHLDVKPANIIV
Kinase TKL6.AA CMGC 120-263 14 6.2e-25 78.07 In-house 1-251 (513) Show / Hide 
Range on Protein: 120-263
Range on HMM: 1-251/513
Sequence Identity: 14% (37 aa)

LNLGETVGRGAFGEVKKAVW----------------RGTTVAVKIISTAGSKKDEVE-------------KEVSIHKRAR-----------------HPN
    . .|.|..|.| |..                  .  ||.|.|. .  ....                |..| |. .                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVSLMAVGHRIG-----------------QVLIVMEFIDGMNLHDVIFRKKD------GITLTPEL------------KMSIT------VGLLSALT--F
||.|  . .. .                 .. .|.|..| ..|...| ....      .. |..              . ...        .| .|   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMD-HDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY

LHASK--ILHLDIKPSNVMVERASRR-------------------AYLCDLGLA
.|  .  |.| |.||.|...    .                      .|| |||
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA
Kinase TKL6.AA STE-Unique 185-379 19 1.7e-22 76.29 In-house 367-616 (616) Show / Hide 
Range on Protein: 185-379
Range on HMM: 367-616/616
Sequence Identity: 19% (48 aa)

GQVLIVMEFIDGMNLHDVIFRKKDGIT--------LTPELKMSITVGLLSALTFLHASK--ILHLDIKPSNVMVERAS----RRAYLCDLGLAHIKTRS-
..| |.||. ..  | . |  |  |.         .  ..   .|  .| .| .||  .  |.| |.||.|..  .       .. .|| |.| ...   
NWVWIFMEYCEHGTLQQII--KRCGCPGNPNNLQLFPETEVIWYTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDH

--------------SMSLS-------------------TSLRGPRGTITHFAPEMVQKQ--GKAWAGPGNDIWSIACTFLELFVEQTLWEGVEFL-KLLR
              .  ..                    .. . .|| .. .|| . ..  .    .   ||||..|..... .   .|     .  .  
FEKDNNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHMQAYIE

TLLKPDAVPP------ILKKVKPEVRTILKPCFDKEPLKRPSAEVLLGQFQK
....    ||      | .| .|| . ..  |....| .||||. ||  | .
MCIHIHCQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase TKL6.AA TK 120-263 14 1.9e-22 71.38 In-house 1-298 (486) Show / Hide 
Range on Protein: 120-263
Range on HMM: 1-298/486
Sequence Identity: 14% (44 aa)

LNLGETVGRGAFG---EVKKAVWRG---------------------------TTVAVKIIS--TAGSKKDEVE----------------KEVSIHK--RA
. ||.. |.|.||   || |. |||                           |.||||..   .| |.... .                 | .. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNIVSLMA-------------VGHRIGQVLIVMEFIDGMN----LHDVIFRKKDGIT-----------------------------------------
.|||||.| .             | .  . ..||||. .. .    |.|   ..... .                                         
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

--------------------------------LTPELKMSITVGLLSALTFLHAS------KILHLDIKPSNVMVERASRR----------AYLCDLGLA
                                ||.. .. . . . ... .||.       .. | |.   |..| .  ..          . ..| ||.
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS
Kinase TKL6.AA Pkinase_Tyr 120-238 26 7.7e-20 67.82 Pfam 1-134 (270) Show / Hide 
Range on Protein: 120-238
Range on HMM: 1-134/270
Sequence Identity: 26% (35 aa)

LNLGETVGRGAFGEVKKAVWR------GTTVAVKII--STAGSK--KDEVEKEVSIHKRA-RHPNIVSLMAVGH-RIGQ--VLIVMEFIDGMNLHDVIFR
. .|.. |.||||||.|..|.      ...||||..  ..  .   ...  .|..| |   .|||||.|..|   . ..  ..||||.  . .|.|   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

K-KDGITLTPELKMSITVGLLSALTFLHASKILH
.  |.  ||.. . .. .   ... .|.. .. |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH
Kinase TKL6.AA TyrKc 120-377 22 4.5e-15 21.09 SMART 1-280 (280) Show / Hide 
Range on Protein: 120-377
Range on HMM: 1-280/280
Sequence Identity: 22% (64 aa)

LNLGETVGRGAFGEVKKAVWRGTTVAVKIISTAGSKKDEVEKEVSIHKRA--RHPNIVSLMAVGHRI-------GQVLIVMEFIDGMNLHDVIFRKKDGI
. ||.. |.|||||| |..|. ..|||| .      . .  .| .| ..   .||||| | .|           ....||||. .. .|.| . ....  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-

TLTPELKMSITVGLLSALTFLHASKILHLDIKPSNVMVERASRRAYLCDLGLAHIKTRS-------SMSLSTSLRGPR--GTITHFAPEMVQKQGKAWAG
 |... . |. .   .   .||  .. | |.   |..|  . ...  .| ||.   .         ..  ... .| .    |   |||   . ||    
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVG-ENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGK--FT

PGNDIWSIACTFLELF-VEQTLWEG-----VEFLKLLRTLLKPDAVPPILK-------KVKPEVRTILKPCFDKEPLKRPSAEVLLGQF
.  |.||   .  |.|   |. ..|     ..   ... . . .  |.             .|. .| | | . .| .||. . .  .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase TKL6.AA STE-Unique 121-177 27 3e-06 17.77 In-house 1-66 (616) Show / Hide 
Range on Protein: 121-177
Range on HMM: 1-66/616
Sequence Identity: 27% (18 aa)

NLGETVGRGAFGEVKKAV--WRGTTVAVKIISTAGSK--K-----DEVEKEVSIHKRARHPNIVSL
|  . .|||.||.| ..     . ..|.| | . . |  .         .|. |.|. .|.||| .
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKY
Kinase TKL6.AA TK 327-377 15 0.000993 7.53 In-house 412-486 (486) Show / Hide 
Range on Protein: 327-377
Range on HMM: 412-486/486
Sequence Identity: 15% (12 aa)

EFLKLLRT---------------LLKP--DAVPP----ILKKVK-----PEVRTILKPCFDKEPLKRPSAEVLLGQF
|....||.               . .|  .  |.       .       .|.  ... |....| .||. . |. |.
EVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase TKL6.AA CMGC 305-325 27 0.010257 3.71 In-house 317-345 (513) Show / Hide 
Range on Protein: 305-325
Range on HMM: 317-345/513
Sequence Identity: 27% (8 aa)

DIWSIACTFLELFVE--------QTLWEG
|.||..| | |..          ..|. |
DMWSVGCIFAEMYTGYQSLIFRGKPLFPG
Kinase TKL6.AA MOS 353-379 33 0.059286 2.02 In-house 273-299 (299) Show / Hide 
Range on Protein: 353-379
Range on HMM: 273-299/299
Sequence Identity: 33% (9 aa)

RTILKPCFDKEPLKRPSAEVLLGQFQK
| . . |  |.|. ||||. |.     
RQLIQKCWPKQPEQRPSARQLKHELEM
Kinase TKL6.AA Pkinase_Tyr 350-377 25 3.673033 1.17 Pfam 243-270 (270) Show / Hide 
Range on Protein: 350-377
Range on HMM: 243-270/270
Sequence Identity: 25% (7 aa)

PEVRTILKPCFDKEPLKRPSAEVLLGQF
.|. ...| | ...| .||. . .. |.
DEIYDLMKQCWHYDPEDRPTFSEIHEQL