Gene F31E3.2 (Nematode worm)

F31E3.2

Species: Nematode worm
Alias: F31E3.2, ceh-20, F31E3.2A, aSWK027, CE30773, F31E3.2a
External Links:
Annotation:

Classification

Group: AGC
Family: RSKR

Sequence

Name Sequence Type Origin Length Description Download
F31E3.2.AA Protein None 436 None Fasta, JSON
F31E3.2.kin_dom Protein Kinase Domain None 270 None Fasta, JSON

Protein domain

Protein domains of F31E3.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase F31E3.2.AA RSKR 121-376 49 7.1e-192 643.72 In-house 1-296 (296) Show / Hide 
Range on Protein: 121-376
Range on HMM: 1-296/296
Sequence Identity: 49% (148 aa)

FVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREASIQ--------------RLLPSHPFIARTYSTWQTRTHLYSLLQYPTGS
.........||||||||.|..||....||||||.||.||....|.|.|.|||||              ||||.||||.|.|.|||.|.|||....||. .
YRIDHLVAKGSFGVVYCVSDCHDQKQCFAIKMQKKRKIIQRNTVRQCKDEASIQRCCQDVTSDHSHFQRLLPHHPFIHRQYDTWQNRHHLYMMCEYPP-C

TGDLFSVWRQRGSLSEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAKKLKQGSSTGTICGTLQYMSPDVASGGTYSHYVDWW
.|||.|.|||||..||.||||..||||.|...||....||||||.||..||||||..|.||||.|..|||..|.|||||||||.|....|..|.|.||||
HGDLYSLWRQRGHFSEMAIRLFIAELAMALCYLHNAGIIYRDVKMENILLDQWGHIKLTDFGLSKWMKQGARTYTICGTLQYMAPEILCGEPYNHAVDWW

SLGVLLHILLTGIYP-----------YPNS--EATHHANLKFIDYSTPIG--------------CSREFANLMDRMLAVSITHRLCSFTVLHAHPFF
||||.....|||.||           |.|.  ..|.||....|||..|..              ||.||..||.|||.....|||||...|..||||
SLGVIMCQMLTGKYPNIKRHLLRRREYDNERDHFTMHASVAHIDYCLPDSDGDSEDFLPEEVQHCSHEFCDLMHRMLCQNPNHRLCSLHHLQHHPFF
Kinase F31E3.2.AA AGC 121-376 20 1.2e-102 265.65 In-house 1-395 (395) Show / Hide 
Range on Protein: 121-376
Range on HMM: 1-395/395
Sequence Identity: 20% (83 aa)

FVLERQLGRGSFGVVYCASAIH-----DSERKFAIKMQEKRE-IISKR--AVLQVKRE------------ASIQRLLPS---------HPFIAR-TYSTW
| . . .|.|||| || .   .     |... .|.|. .|.. |. |.   | ....|              |  .. .         |||| .  ....
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTRTH--LYSLLQYPT--------GSTGDLFSVWR---QRGSLSEAAIRLIGAE-------LASAIDFLHQ-NDVIYRD-VKLENVVLDQWGHALLIDFG
|. .|  || ...|          |  ..||.  .   ..|...| ..| . ||       ...|...||. ...|.|| .|.||..||. ||  | |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKKLK---------------------------------------------------QGSSTGTICG--TLQYMSPDVASGGTYSHYVDWWS--LGVLLH
|.|...                                                   ..  | |.||  | .||.| .     |.. .||||  ||.|. 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ILLTGIYPYPNSE------------ATHHANLKFI-----DYSTP----------IGCSREFANLMDRMLAVSITHRLCSFTV---------LHAHPFF
 .|||. |. . .             ...  .. .     .   |             | |  .|. ..| .  ..|| .            . .||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase F31E3.2.AA S_TKc 121-376 28 1.7e-78 268.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 121-376
Range on HMM: 1-231/231
Sequence Identity: 28% (78 aa)

FVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGS-
. . |..|.|.||.||..  .. . |..|||.             ...|| .| .    ||.| . | ..|. .|||  . |  |..||||.. ..||. 
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LSEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAKKLKQGSSTGTICGTLQYMSPDVASGGTYSH-YVDWWSLGVLLH
     ..|  .| . .....|....|.. .|.||.| ||. ||.  |  ..|||||..|       |.|||. ||.| |     |..  .||||.|..| 
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ILLTGIYPYPNSEATHHANLKFIDYSTPIGCSREFANLMDRMLAVSITHRLCSFTVLH------AHPFF
..|.|  |.|    .... .| |        |.|. ......| .  ..|.    .|.      .||.|
EMLCGYPPFP----QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase F31E3.2.AA Pkinase 121-376 25 7.4e-58 203.33 Pfam 1-293 (293) Show / Hide 
Range on Protein: 121-376
Range on HMM: 1-293/293
Sequence Identity: 25% (78 aa)

FVLERQLGRGSFGVVYCASAIHDSERK-FAIKMQEKREIISKRAVLQVK-REASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTG----DLFSVW
....|..|.||||.||   ..| ...| .|.|  .||.. |.  .  .. .|..| . | .||.| |.| ......|.|  .  .    |    |||.. 
YHIGRKIGSGSFGCVY--KCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIY--MVMEYCEGGLYVMDLFDYI

R--QRGSL--SEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHA----LLIDFGLAKK--LKQGSSTGTICGTLQYMSPDVAS-GGTYSHYV
.  ..|..  ||  .. .  .........|.. .|.||.|.||. .|. ||      ..||||||.  .  .| . |.|||. ||.| |   |  |.. |
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DWWSLGVLLHILLTGIYPYPNS--------EATHHANLK-FIDYSTPIGCS-------------------REFANLMDRMLAVSITHRLCSFTVLHAHPF
|.||.|..|...|.|  |.|..         . .  ...  .... |  ||                   .|.  .....|..  . |.  .. .  ||.
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-AEQILQHPW

F
|
F
Kinase F31E3.2.AA RSK 125-376 29 8.9e-54 184.98 In-house 2-278 (278) Show / Hide 
Range on Protein: 125-376
Range on HMM: 2-278/278
Sequence Identity: 29% (81 aa)

RQLGRGSFGVVYCASAI--HDSERKFAIKMQEKREIISK-RAVLQVKREASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGS--
..||.|..| |.    .  ||... .| |  .|..|. . ...  ...| .|  .  .|||| . . . || ..||  ..|  |  |.||   .....  
KVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRG--GELFTHLQKEKHFG

-LSEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQ---WGHALLIDFGLAKK--LKQGSSTGTICGTLQYMSPDVAS----GGTYSHYVDWWSLG
 .||   . . ||...|...||| ..|.|| |.||...|.    ||  |.|||..|.  ..... | | |.|..|| | .      .|.... .||||||
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VLLHILLTGIYPYPNSEA-THHANLKFIDYST-----P--IGCSREFANLMDRMLAVSITHRLCS----FTVLHAHPFF
||.. .|||  |. ...  ...  .| |   .     |     |.|. .|  .|| .    || .       . .||.|
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase F31E3.2.AA SGK 121-322 31 1.3e-51 157.44 In-house 1-225 (283) Show / Hide 
Range on Protein: 121-322
Range on HMM: 1-225/283
Sequence Identity: 31% (72 aa)

FVLERQLGRGSFGVVYCASAIHD-----------------SERKFAIKMQEKREII-------SKRAVLQVKREA-SIQRLLPSHPFIARTYSTWQTRTH
| .   .| |||| || .    |                  . ..|.| . |  ||        |  .  .. |   |  .. .||||       || . 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNM-KHPFIVNLHYAFQTKWK

LYSLLQYPTGSTGDLFSVWRQRGSLSEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAK-KLKQGSSTGTICGTLQYMSPDVA
||  . |  |  |..|.  . .....|   |   ||...|.. ||  |.|||| | ||..||  ||. | ||||.| . |.   | |.|||. |. | | 
LYFVMDYVNG--GEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVL

SGGTYSHYVDWWSLGVLLHILLTGIYPY
 . ...  ||||.|| .|  ...|. |.
RKQPHDRTVDWWCLGCVLYEMMYGLPPF
Kinase F31E3.2.AA Ciliate-E2b 121-376 28 3.6e-51 153.8 In-house 1-272 (272) Show / Hide 
Range on Protein: 121-376
Range on HMM: 1-272/272
Sequence Identity: 28% (77 aa)

FVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRG--
..   .||.| || ||   .  .... .|.|  .| .|| .   ..  .| .. . .  |||| . . . ..  |.| .. .  |  ..||.| |. |  
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKC-NHPFIMKFIRSFKDDQHMYFMMEFCNG--MELFDVIREIGRL

SLSEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAKKLKQGSS----TGTICGTLQYMSPDVAS-----GGTYSHYVDWWSLG
 ||.   . ..|..  ..  ||.. .||||.| ||. .|. |.  |||.|.|| ... ..    | ||.||. || |.. .     |  |. .|| ||.|
LLSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVG

VLLHILLTGIYPYPNSEATHHANLKFIDYS-TPIG----CSREFA--NLMDRMLAVSITHRL-CSFTVLHAHPFF
. |  .. |  |.       .   ..|     .|.    |. . |  .||...|. ..  ||  |.  | .||.|
ICLYEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF
Kinase F31E3.2.AA Ciliate-E2 121-376 20 3.8e-51 173.81 In-house 1-365 (365) Show / Hide 
Range on Protein: 121-376
Range on HMM: 1-365/365
Sequence Identity: 20% (77 aa)

FVLERQLGRGSFGVVYCASAIHDSERK----------------------FAIKMQEKREIISKRAVLQVKREAS----------IQRLLPSHPFIARTYS
. . ...|.|.||.|| .. . . ...                      .|.|...|..|...  .... ||            |...| .||.| . | 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQL-NHPNIIKMYE

TWQ--TRTHLYSLLQYPTGSTGDLFSVWRQR-----------GSLSEAAIRLIGAELAS---------------AIDFLHQND-VIYRDVKLENVVLDQW
..|  .....|  . |  |  ||||.  ...           ....|  |. | .....               |. .||..  .|.|| |.||...   
CFQEKDDNNIYLVMEYCQG--GDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

GHALLIDFGLAKKLKQGSSTGT--------------------------------ICGTLQYMSPDVASGGT---------YSHYVDWWSLGVLLHILLTG
    .|||||.||... .  .|                                ||||. ||.| . .|.          |.. .|.|||||.|...|.|
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

IYPYPNSEATHHANLK-FIDYSTP----------------IGCSREFANLMDR----MLAVSITHRLCSFTVLHAHPFF
 .|.         ...  ||.. |                  .| |  .|. .    || .    |. ..  .  ||.|
KPPF------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase F31E3.2.AA CAMK 126-376 18 1.3e-49 157.63 In-house 1-425 (425) Show / Hide 
Range on Protein: 126-376
Range on HMM: 1-425/425
Sequence Identity: 18% (80 aa)

QLGRGSFGVVYCASAIHDSE-----------RKFAIKMQEKREIIS------------------------KRAVLQ-VKREASIQRLLP------SHPFI
.|||||||.|. .  ...             .|.|||. .|. . .                        .   .. |.|| .| ..|       .|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ARTYSTWQ------------TRTH--------LYSLL---QYPTGSTG--DLFSVWRQRGS---------------LSEAAIRLIGAELASAIDFLHQND
 . | ...            | ..        .|  .    | .|     |||.  ...|.               ..|.  | .   ..||....|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VIYRDVKLENVVLDQW-----------------GHALLIDFGLAKKLKQ------------------------GSSTGTICGTLQYMS-PDVASGGT---
.. || |.||. ||.                  .   .||||.|.|...                        |    | |||. ||. | | .| .   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YSHYVDWWSLGVLLHILLTGIYPYPNS---------------EATHH----ANLKFIDYS--------------------TPIGCSREF
           |.  .| ||.||.| |.|.| .|.  .               . ...    ..  |...                     ..  .| | 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQEC

ANLMDRMLAVSITHRLCSFTVLHAHPFF
 .|  .|| |  ..|.    .| .||..
KDLIRKMLQVDPEKRMTIEQCL-NHPWM
Kinase F31E3.2.AA MSK 123-332 32 1.6e-49 165.6 In-house 1-222 (277) Show / Hide 
Range on Protein: 123-332
Range on HMM: 1-222/277
Sequence Identity: 32% (72 aa)

LERQ--LGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVL-QVKREASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGS
|.    .| |.|...   .  ||..  .|.|   |  .. || .  ....|... ... .||.|   . . |. .|.|  . | .|  | ||   |.|. 
LKVLGTGGYGKFFICRKCVH-HDTGKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNG--GELFTHIRKREH

LSEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQW---GHALLIDFGLAKKLKQG--SSTGTICGTLQYMSPDVASG-----GTYSHYVDWWSLG
 .|.. | | .|| .|.|..||  .|.|| |.||. .|     ||  |||||.|. . |.    . . |.||.||.|..  .     |.|.  .||||||
FDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLG

VLLHILLTGIYPYP--NSEATHHAN
|.|  .|||  |.    . . | .|
VILYTMLTGQVPFQQNEDDRQHSCN
Kinase F31E3.2.AA Delta 121-376 30 1.3e-44 154.57 In-house 1-259 (259) Show / Hide 
Range on Protein: 121-376
Range on HMM: 1-259/259
Sequence Identity: 30% (80 aa)

FVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSL
|.... ||.|||| |  |  ... .. .|||   |  ..    |     |  .  |   |||... . |.||. ||.  . |  |  |||     | .  
FHFHKVLGKGSFGKVMLA-ELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNG--GDLMYHIQQCHRF

SEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAKK-LKQGSSTGTICGTLQYMSPDVASGGTYSHYVDWWSLGVLLHILLTGI
.|.  |  ..|. ... |||....||||.||.||.||. ||  . |||..|. . . . . | |||  |..|..  |  |.| ||||| |||.  .| | 
DEKRARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQ

YPYP-NSEATHHANLKFIDYSTPIGCSREFANLMDRMLAVSITHRLCS----FTVLHAHPFF
 |.  . |      .       |   ..| .... ...    ..|| .       ...|.||
SPFHGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase F31E3.2.AA AktR 121-319 32 2.7e-42 146.84 In-house 1-202 (268) Show / Hide 
Range on Protein: 121-319
Range on HMM: 1-202/268
Sequence Identity: 32% (66 aa)

FVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSL
|.. . ||.| || || .    |. ...|.||  | .|| ...  .. .|  |   . .|||| . . ..||...|. ...|  |  |.||.. .... .
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPG--GELFQHLKKKKKF

SEAAIRLIGAELASAIDFLHQN-DVIYRDVKLENVVLDQWGHALLIDFGLAK--KLK-QGSSTGTICGTLQYMSPDVASG-GTYSHYVDWWSLGVLLHIL
||  .| . |.   |...|||. ..|||| | || .||. ||  ..||||.|  . .     . ..||| .||.|..      .   ||||..|...  .
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEM

LTGI
.||.
VTGC
Kinase F31E3.2.AA TyrKc 121-376 21 2.4e-11 -39.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 121-376
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

FVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREASIQRLL-PSHPFIARTYSTWQTR-------THLYSLLQYPTGSTGDLFS
 .|...||.| ||.|| . ..    .. |.||  .        .    |||.| . | ..|| | | |    .          |. .. |  .  ||| .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH--GDLKD

VWRQRGS-LSEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAKKLKQG------SSTGTI----CGT----LQYMSPDVASGG
  | ..  |. .    .    |.  ..||.. .| ||    |. ..  ...   ||||..... .      ... .     .|     .  |.| .   |
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

TYSHYVDWWSLGVLLH-ILLTGIYPYPN--------SEATHHANLKFIDYSTPIG-------CSREFANLMDRMLAVSITHRLCSFTVLHAHPFF
....  | || ||..  |.  |  |||.        .|. ..    .     | .       |. |  ..| .  .     | ..|. .  | .|
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR-PTFSEI--HECF
Kinase F31E3.2.AA Pkinase_Tyr 121-185 28 6e-06 20.86 Pfam 1-68 (270) Show / Hide 
Range on Protein: 121-185
Range on HMM: 1-68/270
Sequence Identity: 28% (20 aa)

FVLERQLGRGSFGVVYCASAI---HDSERKFAIKMQEKREIISKRA--VLQVKREASIQRLLPSHPFIAR
 .. ..||.|.||.|| . .     . . . |.||   .|  ....       |||.| . |..|| | |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVR