Gene ZK507.1 (Nematode worm)

ZK507.1

Species: Nematode worm
Alias: aSWK458, ZK507.1
External Links:
Annotation:

Classification

Group: CK1
Family: CK1-Unique

Sequence

Name Sequence Type Origin Length Description Download
ZK507.1.AA Protein None 331 None Fasta, JSON

Protein domain

Protein domains of ZK507.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ZK507.1.AA CK1-Unique 2-240 33 7.69999999999e-111 374.53 In-house 20-337 (337) Show / Hide 
Range on Protein: 2-240
Range on HMM: 20-337/337
Sequence Identity: 33% (108 aa)

QVNEEGFAIDDKEYAMKTELKFASKHSSRLKIERNVMESYSKCDAQCK--EHFSELIDFGQSPVWKWIVMTIVGPSLEELKMKYKPSDIPPS------TI
.||...|.|||..|.|||| .|..||..||.|||||| ...||..|||  .||.|..||.|...|.|||||..|||.||..|..|.......      ..
FVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEECCMMMKNFQFTLNEKKNQLCA

LQCGLQTMKAIHDFHQIGFLHRDIKPANYCIGYGS--KSETIYVLDFGLARK--YRLPNGQVRPPRPKTKMIGTPRYCSRASHRCEELGRRDDYESWFFM
.|||.|.  .|   |. ||.||..||.||| .  |  .  ..|.||.|  |.     .|.|.|.|||.|...|...||....|.|.|.|||||.||||.|
IQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKDYCPCSCHQCREHGRRDDMESWFYM

FIDLVDTT-------------------------------------------------------LIDWKGLTRPDAYAKKQE------------LFTKLKT
...||..|                                                       ...||||.|..||.|...            ||.|.|.
LYHLVHNTRGLSWKLDKIIPSGIDNIIVYLRGLKFEDPVDYRQIENELRTAGKKMAPSDSSDEKMCWKGLRRQNAYDKHKNYQNSKQFNEKPCLFCKIKP

YEKHPMFKVISIYLDNLV
... .|....|.|..   
HNDMKMYCCMSEYFYMFN
Kinase ZK507.1.AA CK1 12-250 25 3.8e-78 265.94 In-house 35-339 (339) Show / Hide 
Range on Protein: 12-250
Range on HMM: 35-339/339
Sequence Identity: 25% (78 aa)

DKEYAMKTELKFASKHSSRLKIERNVMESYSKC---------------DAQCKEHFSELIDFGQSPV-WKWIVMTIVGPSLEELKM-KYKPS-DIPPSTI
..|||||.| | . .....|..| ....   ..               ... . |.  ... |  .  ....||| .||.||.|.. .  .   .  .|.
GEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEEDDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTW

LQCGLQTMKAIHDFHQIGFLHRDIKPANYCIGY-------------GSKSETIYVLDFGLAR-KYRLPNGQV------------RPPRP---KTKMIG-T
|....|...|. . | .||.||||||.|.|.|.             .... ..|..|||.|| ||| ..|..            ||||.   |....| |
LMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCT

PRYCSRASHRCEELGRRDDYESWFFMFIDLVDTT-LIDWKGLTRPDA------YAKKQELFTKLKTYE------------KHPMFKVISIYLDNLVYDSE
.||||...|.. |.||||| .|||.|.|.... | .  |.......         .|.| ... | .              .. |  |  |...| |...
ARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDR

VKFGVL
 .   .
PDYEMI
Kinase ZK507.1.AA Worm6 11-194 35 2.1e-61 210.32 In-house 22-215 (279) Show / Hide 
Range on Protein: 11-194
Range on HMM: 22-215/279
Sequence Identity: 35% (69 aa)

DDKE---YAMKTELKFASKHSSRLKIERNVMESYSKCDAQCKEHFSELIDFGQSPV--WKWIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIH
.||.   .||| | . .. ... ||.| .|.    ..   |. || ...| |. .    ..||||.||..|..|..      .  .| |....|. .|| 
SDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHK--CR-HFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRKFSMGTGLKIAIQCLEAIE

DFHQIGFLHRDIKPANYCIGY-----GSKSETIYVLDFGLAR--KYRLPNGQVRPPR-PKTKMIGTPRYCSRASHRCEELGRRDDYESWFFMFIDLV
| |..||.|||.||.|.|||        .. ||| ||||..|  ||.  ....|.|| .. .  ||.||...|.|.  |..|.|| |||| | ....
DLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMI
Kinase ZK507.1.AA TTBKL 12-254 26 1.7e-51 172.15 In-house 25-288 (288) Show / Hide 
Range on Protein: 12-254
Range on HMM: 25-288/288
Sequence Identity: 26% (72 aa)

DKEYAMKTELKFASKHSSRLKIERNVMESYSKCDAQCKEHFSELIDFGQSPVWKWIVMTIVGPSLEELKMKYKPSD-IPPSTILQCGLQTMKAIHDFHQI
....||| |... .. .||.|.| .|.   .. .   . || .... |. .   ..||| .||.|  |... .  . . ..|.. .| |. .|. . | .
KDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNG---SPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDC

GFLHRDIKPANYCIGYGSK----SETIYVLDFGLARKYRLPNG-----------QVRPPRP---KTKMIGTPRYCSRASHRCEELGRRDDYESWFFMFID
||.|||.||.|.|.|| ..    . ..|..|||.||.|. ..|           ..|.||.   |.   ||.|||| . |.  |.|| ||  ||..|.| 
GFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIE

LVDTTLIDWKGLTRPD-AYAKKQELFTKLKTYEKH------PMFKVISIYLDNLVYDSEVKFGVLREAI
|..  |  |.... ..  ...|... ...  ...       . |  .  .| .| | ..   . ..| .
LHCG-LP-WTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase ZK507.1.AA Dual 12-254 32 5.2e-46 152.64 In-house 28-282 (282) Show / Hide 
Range on Protein: 12-254
Range on HMM: 28-282/282
Sequence Identity: 32% (83 aa)

DKEYAMKTELKFASKHSSRLKIERNVMESYSKCDAQCK----EHFSELIDFGQSPVWK--WIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIH
.| |..|||     |   |||.|  ||   .    . |    ..| |..| |..   |  ..||  .||||.|   ||       ..    ..|...|| 
NKCYILKTESEEGEKMMLRLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSLQEIRRKYIMGQLSMHCSFNVAIQMLRAIQ

DFHQIGFLHRDIKPANYCIGYGSKSETIYVLDFGLARKYRL-PNGQVRPPRPKTKMIGTPRYCSRASHRCEELGRRDDYESWFFMFIDLVDTTL-IDWKG
| |.||.|||.|||||. .| | .  |.| .||...|||    |...|..| | || |. || .||     . || || |.|  |  || |    . |. 
DLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKDQGRKDDLECWIYMVFDLMDPEHGMSWRK

LTRPDAYAKKQELFTKLK---TYEKHP-MFKVISIYLDNLVYDSEVKFGVLREAI
. ..    |. ..|   .   .| . |  .| . .| ... |||     ..|  .
ECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL
Kinase ZK507.1.AA TTBK 47-194 40 1.4e-37 130.37 In-house 53-201 (257) Show / Hide 
Range on Protein: 47-194
Range on HMM: 53-201/257
Sequence Identity: 40% (60 aa)

QCKEHFSELIDFGQSPVWKWIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIHDFHQIGFLHRDIKPANYCIG-YGSKSETIYVLDFGLARKYR
| ..|    |  |    . ..||.. | .| .|  |        || |. |.| ...|   |..||||||||| |. .|   |.   .| |||||||.| 
QGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYT

LPNGQVRPPRPKTKMIGTPRYCSRASHRCEELGRRDDYESWFFMFIDLV
.  |.|||||. .   || || |  .||  |.||.||  | |.| .  |
NACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFV
Kinase ZK507.1.AA CK1-Unclassified 107-185 40 4.9e-30 85.86 In-house 120-201 (244) Show / Hide 
Range on Protein: 107-185
Range on HMM: 120-201/244
Sequence Identity: 40% (33 aa)

FHQIGFLHRDIKPANYCIG-YGSKSETIYVLDFGLARKYRLP--NGQVRPPRPKTKMIGTPRYCSRASHRCEELGRRDDYES
.|  .|.|||||| |...| .| .. ..|  ||||. .|. .  .|.  | | . ...|| || |  .|.. | .|||| ||
LHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLES
Kinase ZK507.1.AA CK1-D 58-214 36 6e-25 84.86 In-house 63-215 (261) Show / Hide 
Range on Protein: 58-214
Range on HMM: 63-215/261
Sequence Identity: 36% (57 aa)

FGQSPVWKWIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIHDFHQIGFLHRDIKPANYCIGYGSKSETIYVLDFGLARKYRLPN-GQVRPPRP
.||   .  .|| ..|||||.|   |        |.|  ..| .. |.  |   |.|||||| |. .| | . ...|..|||||..|| ..  |  | | 
CGQEGDYNVMVMDLLGPSLEDL-FNYCHRKFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRE

KTKMIGTPRYCSRASHRCEELGRRDDYESWFFMFIDLVDTTLIDWKGLTRPDAYAKKQ
.  . || || |   |.  |  |||| ||  ....     .|  |.||    |..|.|
NKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNRGSLP-WQGL---KAATKRQ
Kinase ZK507.1.AA CK1 92-185 41 4.2e-23 76.5 In-house 106-201 (271) Show / Hide 
Range on Protein: 92-185
Range on HMM: 106-201/271
Sequence Identity: 41% (40 aa)

TILQCGLQTMKAIHDFHQIGFLHRDIKPANYCIG-YGSKSETIYVLDFGLARKYR-LPNGQVRPPRPKTKMIGTPRYCSRASHRCEELGRRDDYES
|.|  . |  . |  .|  .|.|||||| |...| || .. ..|. ||||| .||   ..|  | | . ...|| || |  .| . | .|||| ||
TVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDMES
Kinase ZK507.1.AA CK1-A 58-214 34 4e-21 71.26 In-house 63-215 (261) Show / Hide 
Range on Protein: 58-214
Range on HMM: 63-215/261
Sequence Identity: 34% (54 aa)

FGQSPVWKWIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIHDFHQIGFLHRDIKPANYCIGYGSKSETIYVLDFGLARKYRLPNGQVR-PPRP
.|.   .  .|| ..|||||.|   .        |.|    | .  |   |. .|.|||||| |. .| |     ....|||||.||| .. .   | | 
YGCEKDYNVMVMDLLGPSLEDL-FNFCKRRFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYRE

KTKMIGTPRYCSRASHRCEELGRRDDYESWFFMFIDLVDTTLIDWKGLTRPDAYAKKQ
  ...|| || |   |   |  |||| ||  ....    ..|  |.|..   | .|||
DKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGKLP-WQGMK---AMTKKQ
S_TKc ZK507.1.AA S_TKc 1-229 15 3.8e-08 -57.53 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-229
Range on HMM: 1-231/231
Sequence Identity: 15% (44 aa)

MQVNEE-----------GFAID-DKEYAMKTELKFASKHSSRLKIERNVMESYSKCDAQCKEHFSELIDFGQSPVWKWIVMTIVGPSLEELKMKYKPSD-
 .. ..           .  .. ....|.|           ... |......         ..   |.|. |.    ..||  .. .| .|.   |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------IPPSTILQCGLQTMKAIHDFHQIGFLHRDIKPANYCIGYGSKSETIYVLDFGLARKYRLPNGQVRPPRPKTKMIGTPRYCS--RASHRCEELGR
      .|. ..     |. .|.   |. |..|||.||.|  .       .| . ||||||..             | ..||| |..           |.
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL-----GYGK

-RDD--------YESWF----FMFIDLVDTTLIDWKGLTRPDAYAKKQELFTKLKTYE----------K-------HPMF
 . |        ||       |      . ....  |           ..  |. ...          .       || |
CKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase ZK507.1.AA Pkinase 108-168 32 3e-06 23.37 Pfam 125-179 (293) Show / Hide 
Range on Protein: 108-168
Range on HMM: 125-179/293
Sequence Identity: 32% (20 aa)

HQIGFLHRDIKPANYCIG-YGSKSETIYVLDFGLARKYRLPNGQVRPPRPKTKMIGTPRYCS
|. |..|||.||.|  |   |  .... . |||||....       . .  |   |||.|..
HSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMA
Kinase ZK507.1.AA CK1 12-84 25 0.09616 2.02 In-house 27-99 (271) Show / Hide 
Range on Protein: 12-84
Range on HMM: 27-99/271
Sequence Identity: 25% (20 aa)

DKEYAMKTELKFASKHSSRLKIERNVMESYSK--CDAQCKEHFSELIDFGQS--PVWKWIVMTIVGPSLEELKMKYK
. ..|.| | |  |||.  |..|  ..    .  |     ...  .. .||        .||.  |||||.|.....
N-HVAIKLE-KNKSKHP-QLHYEAKIYKILQGHNC-DNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCN