Gene FGTK4 (M.brevicollis)
FGTK4
Species: M.brevicollis
Alias: FGTK4
External Links:
Annotation:
Sequence
Protein domains of FGTK4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| FG-GAP | FGTK4.AA | FG-GAP | 44-73 | 16 | 9.3e-05 | 19.33 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 44-73 Range on HMM: 1-35/35 Sequence Identity: 16% (6 aa) GPVESLFADLDGDGLNDLLI------AGEGDSLIFW .. ..|..|||..||.. .. .... . FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 94-125 | 21 | 0.000668 | 16.45 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 94-125 Range on HMM: 1-35/35 Sequence Identity: 21% (8 aa) HGVVAMLAHDLDKDGLLDVVS------ANAGDDSIVVF | .. .. |.. ||..|.| .| . ....|. FGWSVAVG-DFNGDGYPDLVVGAPYNGGN-N-GAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 146-176 | 27 | 1e-06 | 25.48 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 146-176 Range on HMM: 1-35/35 Sequence Identity: 27% (10 aa) NLHAIACADLDGDGYADIIS------ARDGTGAVAWH . ...| .|..||||.|.. . . ||| FGWSVAVGDFNGDGYPDLVVGAPYNGGN-N-GAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 200-229 | 25 | 0.000126 | 18.88 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 200-229 Range on HMM: 1-35/35 Sequence Identity: 25% (9 aa) NVRNVALADLDGDGAMDIVA------ARLDTNVVMW . . ||..|..||| |.|. . . .|. . FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 249-278 | 22 | 0.00027 | 17.77 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 249-278 Range on HMM: 1-35/35 Sequence Identity: 22% (8 aa) GVRALAAADMDQDGHVDVVS------LNAGEDLIVW . ...|..|...||. |.| | . . |. FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 355-384 | 19 | 0.181145 | 8.28 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 355-384 Range on HMM: 1-35/35 Sequence Identity: 19% (7 aa) SVDALLVGDMDDDDLHDFLV------VSKNENSVIW .. |||.. | . |..| . | . ... FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 404-423 | 40 | 0.008745 | 12.7 | Pfam | 1-20 (35) | Show / Hide |
Range on Protein: 404-423 Range on HMM: 1-20/35 Sequence Identity: 40% (8 aa) GVLGLAAGDLDGNGQPDLIT . ..|.||..|.| |||.. FGWSVAVGDFNGDGYPDLVV |
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| FG-GAP | FGTK4.AA | FG-GAP | 455-484 | 16 | 0.128566 | 8.78 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 455-484 Range on HMM: 1-35/35 Sequence Identity: 16% (6 aa) GVNKVELLDLDKDGDLDVVF------SALDANILGW . . | . |.. ||..|.| .. . .. . FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 505-535 | 19 | 0.010669 | 12.41 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 505-535 Range on HMM: 1-35/35 Sequence Identity: 19% (7 aa) GPSTFGVADMDNDGHIDIVGA-----SETASFIAWY .... .|.|...||. |.| . .. . . | FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 556-586 | 27 | 0.000174 | 18.41 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 556-586 Range on HMM: 1-35/35 Sequence Identity: 27% (10 aa) ITYTLAMADLNGDGTVDVVAA-----HYGDDTVAWY ....| .|.|||| |.|.. . ...| | FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 607-634 | 38 | 5.8e-05 | 20.02 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 607-634 Range on HMM: 1-35/35 Sequence Identity: 38% (14 aa) GATGVVAGDVNGDGLPDLVS------ISLN--NYVA . ..| .||.||||.|||| . | || FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 657-687 | 19 | 6e-06 | 23.36 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 657-687 Range on HMM: 1-35/35 Sequence Identity: 19% (7 aa) GPRSLSLTDLDNDGDLDLVIV-----STLDNIISFF ...|... |...||..|||. .. .. .. . FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 711-737 | 25 | 0.007367 | 12.95 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 711-737 Range on HMM: 1-35/35 Sequence Identity: 25% (9 aa) QARALVVADISNDGHPDIVA--------AGQSQVF ... |.|. .||.||.|. .|. |. FGWSVAVGDFNGDGYPDLVVGAPYNGGNNGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 760-779 | 30 | 0.00707 | 13.01 | Pfam | 1-20 (35) | Show / Hide |
Range on Protein: 760-779 Range on HMM: 1-20/35 Sequence Identity: 30% (6 aa) SITGLAPADIDGDGNMDVAW ...|..|..||| |... FGWSVAVGDFNGDGYPDLVV |
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| FG-GAP | FGTK4.AA | FG-GAP | 810-840 | 27 | 1.2e-05 | 22.32 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 810-840 Range on HMM: 1-35/35 Sequence Identity: 27% (10 aa) GAQNIEAGDMDGDGLTDILV------TSYLLDGVYLY . . . .||..|||..|..| . . ||.| FGWSVAVGDFNGDGYPDLVVGAPYNGGN-N-GAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 860-889 | 11 | 0.000422 | 17.12 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 860-889 Range on HMM: 1-35/35 Sequence Identity: 11% (4 aa) GAVALNLADLDQDGDLDILC------FGHYAQTILW . .. ..|...||..|.. .. . . .. FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 909-939 | 18 | 3e-06 | 24.55 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 909-939 Range on HMM: 1-35/35 Sequence Identity: 18% (7 aa) GVRALRAVDLDGDGDLDVLI------AAQGVNPVQVL . ... ..|..|||..|... .. . . | |. FGWSVAVGDFNGDGYPDLVVGAPYNGGN-N-GAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 960-989 | 16 | 3.7e-05 | 20.67 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 960-989 Range on HMM: 1-35/35 Sequence Identity: 16% (6 aa) YAQNAEAVDLDGDGLLDVVI------TAPADQILFW . . . ..|..|||..|.|. . .... . FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 1012-1040 | 26 | 0.003326 | 14.11 | Pfam | 3-35 (35) | Show / Hide |
Range on Protein: 1012-1040 Range on HMM: 3-35/35 Sequence Identity: 26% (9 aa) YALTVVDFDKDGDLDLITT-----SLVPGNVILF ....|.||. ||..||... . |.| .. WSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK4.AA | FG-GAP | 1058-1077 | 35 | 0.017966 | 11.65 | Pfam | 1-20 (35) | Show / Hide |
Range on Protein: 1058-1077 Range on HMM: 1-20/35 Sequence Identity: 35% (7 aa) SAASTAAVDLTGNGFVDIIV .| |..|..|.|. |..| FGWSVAVGDFNGDGYPDLVV |
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| Kinase | FGTK4.AA | FGTK | 1269-1504 | 66 | 3.1e-194 | 651.55 | In-house | 1-241 (302) | Show / Hide |
Range on Protein: 1269-1504
Range on HMM: 1-241/302
Sequence Identity: 66% (160 aa)
LAIKAPLGAGNFGTVFKATVVRHREQFNHASVVALKTFDAVEAMDYKAVMMEAALLHTACDHTHVVRLLAVVDDSVPIGLVLELADLGDLRSYLRQQAG-
|....|||.||||||.||...||||||.|. |||.||||.|..||||||||||||.|.||||.|.|.|.|||.|..||.||||.||.|||||.||||..
LQDQPPLGKGNFGTVYKAIPNRHREQFQHQ-VVAVKTFDDVQMMDYKAVMMEAALMHMACDHPHIVQLIAVVHDCMPIALVLEYADHGDLRSFLRQQDAH
----SLSDDAKITSGLRHVHDCDLVHRDLASRNVLLFRRT-HAVPLAKLGDFGLSRYLSKDHDYYKTAQLDDMPFRWLSPEALRRGNFTFASDIWSLGVT
.|...|.|||||.|||||.|||||.|.||||||.|. .|.|.|||.|||||||.|.|||||...|||||||||..|||||.|.|..|||.||||||
NQEMQLQWMAHITSGLCHVHDCQLVHRDMACRNVLLFSRPHMACPQAKLADFGLSRYVSDDHDYYRASQLDDMPFRWMAPEALRHGRFSPASDVWSLGVT
LWEIYNEGKTPYGARTLQMIIEMLNTDARLSLSQFPESLAHL
.|||.|.|.||||.||.|||.|.|....||.||..|..|.||
IWEIFNQGQTPYGERTMQMILEFLQSGQRLDLSHIPPALHHL
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| Kinase | FGTK4.AA | TK | 1269-1496 | 17 | 1.9e-71 | 238.54 | In-house | 1-439 (486) | Show / Hide |
Range on Protein: 1269-1496
Range on HMM: 1-439/486
Sequence Identity: 17% (77 aa)
LAIKAPLGAGNFG---TVFKATVVRH----------------------REQFNHASVVALKTFDAVEAMDYKA--------------VMMEAALLHT-AC
. . ||.|.|| .|.|... .. ... | || || .... .. ..|..... ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
DHTHVVRLLAVVDDSVP------------IGLVLELADLGD----LRSYLRQQAGSLSDDAK--------------------------------------
.| ..|||..|. ...| . .|.|....|| ||.|||. . .. .
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
------------------------------------------ITSGLRHVHDC------DLVHRDLASRNVLLFRRTH-------AVPLAKLGDFG----
| .|... |.. .|||||| ||.|.... . .| .|..|||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ
----LSRYLSKDHDYYKTA-----------------------QLDDMPFRWLSPEALR---------RGNFTFASDIWSLGVTLWEIYNEG-KTPYGART
|.|.. .|.|||.. . . .|.||..||.|. | || .||.||.||..|||. | ...|| .
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS
L---------QMIIEMLNT------------DARLSLSQ
| ..|.| . |. . |
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQ
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| Kinase | FGTK4.AA | Pkinase_Tyr | 1269-1492 | 29 | 7.5e-60 | 203.33 | Pfam | 1-235 (270) | Show / Hide |
Range on Protein: 1269-1492 Range on HMM: 1-235/270 Sequence Identity: 29% (71 aa) LAIKAPLGAGNFGTVFKATVVRHREQFNHASVVALKTF-DAVEAMD--YKAVMMEAALLHTACDHTHVVRLLAVVD-DSVP--IGLVLELADLGDLRSYL . . ||.|.||.|.|.| .. |. || |. . . .. | ||..... ..| ..|||..|. .. | | .|.|.. .|||..|| ITFGKKLGEGAFGEVYKGTWKG--DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL RQQ---AGSLSDDAK------ITSGLRHVHDCDLVHRDLASRNVLLFRRTHAVPLAKLGDFGLSRYLSKDHDYY-KTAQLDDMPFRWLSPEALRRGNFTF |.. ..|. . | .|. . .. ..||||| ||.|. . .| .||||.|.. . ||| .... ..| .|..||... | || RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTT ASDIWSLGVTLWEIYNEGKTP-YGARTLQMIIEML-NTDARL .||.|| ||..|||. |..| | . . ..|.. |. KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRM |
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| Kinase | FGTK4.AA | UTK | 1269-1475 | 31 | 1.9e-58 | 198.52 | In-house | 1-242 (296) | Show / Hide |
Range on Protein: 1269-1475 Range on HMM: 1-242/296 Sequence Identity: 31% (77 aa) LAIKAPLGAGNFGTVFKATVVRHREQFNHASVVALKTFD----AVEAMD-YKA-VMMEAA---LLHTACD-HTHVVRLLAVVDDSVPIGLVLELADLGDL ... ..||.|.||.|.||.... .|. ..||.|. . | ... | . .|.||. .. ... | .|.||..|. .. |. .|.|.. ||| VQLGRQLGQGAFGEVHKARFTQCSEH-MYEMDVAVKVCQHHADAQQEPEPY-PDFMEEARELQMM-KQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDL RSYLR---QQAG----SLSDD------AKITSGLRHVHDCDLVHRDLASRNVLLFRR----THAVPLAKLGDFG---LSRYLSK--------DHDYYKTA ||||| .... .|... . | .|. . | | .|||||| ||.|... . ..|..||| .||... . .||. . RSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWH-CMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQ QLDDMPFRWLSPEALRRG-NFTFASDIWSLGVTLWEIYNEGKTPYG . | .|.|| .|||| . ||..||.||.||..|||. |..||. HQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYP |
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| Kinase | FGTK4.AA | TyrKc | 1269-1537 | 25 | 1.6e-47 | 165.07 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 1269-1537
Range on HMM: 1-280/280
Sequence Identity: 25% (79 aa)
LAIKAPLGAGNFGTVFKATVVRHREQFNHASVVALKTFDAVEAMDYKAVMMEAALLHTA-CDHTHVVRLLAVVDDS-------VPIGLVLELADLGDLRS
. . || |.||.|.|.| || |. . .. | || ... .| ..|||..|. .. |. .|.|....|||..
ITLGKKLGEGAFGEVYKGTWK---------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD
YLRQQAGSLSDDAK------ITSGLRHVHDCDLVHRDLASRNVLLFRRTHAVPLAKLGDFGLSRYLSKD------HDYYKTAQ--LDD--MPFRWLSPEA
||| . |. . . | .| .. |. ..||||| ||.|. .. .| .||||||.. | .|||.... . .| ||..||.
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC
LRRGNFTFASDIWSLGVTLWEIYNEGKTPYGA-----RTLQMIIEMLNTDARLSLSQF---------PESLAHLVSKIESARAKTSFFKKRRSMDELGFV
.. | ||..||.|| ||..|||. |..|| . | .|| . . |. . |. . . .. . . ..| .. |.
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDP-----EDRPTFSEI---
SGDQSRF
..|
---HECF
|
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| Kinase | FGTK4.AA | Fer | 1269-1476 | 30 | 3.1e-44 | 148.57 | In-house | 1-221 (283) | Show / Hide |
Range on Protein: 1269-1476 Range on HMM: 1-221/283 Sequence Identity: 30% (69 aa) LAIKAPLGAGNFGTVFKAT-VVRHREQFNHAS---VVALKTF--DAVEAMDYKAVMMEAALLHTACDHTHVVRLLAVVDDSVPIGLVLELADLGDLRSYL .. || |.||.|.|.. ... . .| |. |. ... .. | .| || .. . || .||.. | | || .|.|... |.|.||| VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL RQQAG-SLSDDAKIT------SGLRHVHDCDLVHRDLASRNVLLFRRTHAV-PLAKLGDFGLSRYLSKDHDYYKTA-QLDDMPFRWLSPEALRRGNFTFA . . ..||. || .|... | .|||.|.||.|. . . . |. |||.|| .|.. || . .. .| |||.||... | .... KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKC--KISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPK SDIWSLGVTLWEIYNEGKTPYGA .|.|| ||..|||.. |..||.. TDVWSFGVMCWEIFTNGAEPYPG |
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| Kinase | FGTK4.AA | RTKA | 1269-1512 | 25 | 2.5e-42 | 146.08 | In-house | 1-314 (314) | Show / Hide |
Range on Protein: 1269-1512 Range on HMM: 1-314/314 Sequence Identity: 25% (81 aa) LAIKAPLGAGNFGTVFKATVVRH-REQFNHASVVALKTFD---AVEAMDYKAVMMEAALLHTACDHTHVVRLLAVV---DD---SVPIGLVLELADLGDL ... ..| |.|..| .| .. | . ||.| | .. . | | |. ||| .|. |...| |. .| .|.|.| .. | | MQVRHVVGHGHFSQVYQASLQDMEDEMRQGPQCVAIKECDDLMLNDKTTLSAWMREIMLLHSMRDCPHIIGLHGVCLPREDKHHQSHCGMVCEWCPHGNL RSYLRQQA-------------GS---------LSDD---------A----KITSGLRHVHDCDLVHRDLASRNVLLFRRTHAVP--LAKLGDFGLSRYLS | .||.. | || . . .. ... . |. ||||.| |||| .. . | . ||.|||||| .. RDFVRQHPHFSAPVVATIAMQHSGEPNASPKLLSEAQCHQALLQMCPCWAQVAQAMAYLAKCGIVHRDVAARNVLVMS---LQPAFHCKLADFGLSRVMP KDHDYYKTAQLDDMPFRWLSPEALRRGNFTFASDIWSLGVTLWEIYNEGKTPYG------------------------------ARTLQMIIEMLNTDAR .. |||| . |.||||| ||... . .|| ||.|| .||. . | ||.. | || || .. SS-DYYKSRADDEMPFRWMAPECIMERRYSEHSDVWSFGVLVWELLTHGQTPWQNCESHQIVALLMRGERLTFAPTINAALRDSGCDLHHIIQMLKQGQT LSLSQFPESLAHLVSKIESAR |. .| .. ... . .. LP---MPPCCPPCLQRFCFWC |
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| Kinase | FGTK4.AA | TK-Unique | 1269-1475 | 26 | 1.5e-40 | 137.54 | In-house | 1-241 (294) | Show / Hide |
Range on Protein: 1269-1475 Range on HMM: 1-241/294 Sequence Identity: 26% (64 aa) LAIKAPLGAGNFGTVFKATVVRHREQFNHASVVALKTFD-AVEAMDYKAVMMEAALLHTACDHTHVVRLLAVVDDSV-PIGLVLELADLGDLRSYLRQQA | .. .| |.||.|....|.. . ... ..||.|. . | .. . |.... || ..|..| . .| | ...| . |.|..|||. . LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR GS-------------------------LS-DDAK-----ITSGLRHVHD--CDLVHRDLASRNVLLFRRTHAVPLAKLGDFGLSRYLSKDHDYYKTAQLD . .| | | .|. . . . |||||..||||| . .|..|||..|.......| .. . PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE----DKVCKICDFGMARDVYTNGVYSMMCSQG DMPFRWLSPEALR--RGNF-TFASDIWSLGVTLWEIYNEGKTPYG .| ||..||.|. .|.. | ||.||.||..||| |..||. RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYP |
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| Kinase | FGTK4.AA | Src | 1269-1474 | 31 | 2.7e-39 | 131.15 | In-house | 1-201 (255) | Show / Hide |
Range on Protein: 1269-1474 Range on HMM: 1-201/255 Sequence Identity: 31% (68 aa) LAIKAPLGAGNFGTVFKATVVRHREQFNHASVVALKTFDAVEAMDYKAVMMEAALLHTACDHTHVVRLLAVVDDSVPIGLVLELADLGDLRSYLR-QQAG . . ||.|.|| |.... .| || || . |. .| || .. . ..| ..|.|.||... || | |. | | ||. .. | IKLCRKLGQGQFGEVWMGY-------WNGNTKVAVKTLKPGT-MSPEAFLQEAQIM-KKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEG S-------LSDDAKITSGLRHVHDCDLVHRDLASRNVLLFRRTHAVPLAKLGDFGLSRYLSKDHDYYKTAQLDDMPFRWLSPEALRRGNFTFASDIWSLG . .. | . .| ..||||| |||| ..| .|||| | . .| | | . .| .| |||...|.|| || || | RHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENN----VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFG VTLWEIYNEGKTPY . |.|| |..|| ILLTEIVTYGRVPY |
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| Kinase | FGTK4.AA | Ack | 1320-1492 | 36 | 6.6e-39 | 128.87 | In-house | 52-231 (266) | Show / Hide |
Range on Protein: 1320-1492 Range on HMM: 52-231/266 Sequence Identity: 36% (68 aa) EAALLHTACDHTHVVRLLAVVDDSVPIGLVLELADLGDLRSYLRQQAG-------SLSDDAK-ITSGLRHVHDCDLVHRDLASRNVLLFRRTHAVPLAKL |.| .| . || |.||| || |. . .| ||| .| | ||.... |.| . |..|.| . . ..||||| ||.|||.. ..| EVAIMH-SLDHPHLVRLYGVVLDQPMLMMVTELAPCGSLLDCLRKHCRTAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDD---RKVKI GDFGLSRYLSKDHDYYKTAQLD--DMPFRWLSPEALRRGNFTFASDIWSLGVTLWEIYNEGKTPYGARTLQMIIEMLN-TDARL .||||.| | |||... || | ||.|| . |. |||.|. |||||| | |. ... |.. . .|| CDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGVTLWEMFSYGEEPWAGCNGYQILQKIDKEGERL |
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| Kinase | FGTK4.AA | RTKF | 1387-1475 | 49 | 1.2e-29 | 92.5 | In-house | 127-214 (272) | Show / Hide |
Range on Protein: 1387-1475 Range on HMM: 127-214/272 Sequence Identity: 49% (44 aa) LVHRDLASRNVLLFRRTHAVPLAKLGDFGLSRYLSKDHDYYKTAQLDDMPFRWLSPEALRRGNFTFASDIWSLGVTLWEIYNEGKTPYG |||||.| |||| | . . || |||| | || ||| .| .. |||| ||| || ||.|| |. |.| | ||| LVHRDVAARNVLVFEDQPRM-YVKLTDFGLARVLSQHQDYYRSMQNEELPFRWMAPEAIMHRRFTQKSDVWSFGMMLFELFTRGDVPYG |
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| Kinase | FGTK4.AA | S_TKc | 1269-1518 | 20 | 2.8e-29 | 104.5 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1269-1518 Range on HMM: 1-231/231 Sequence Identity: 20% (56 aa) LAIKAPLGAGNFGTVFKATVVRHREQFNHASVVALKTFDAVEAMDYKAVMMEAALLHTACDHTHVVRLLAVVDDSVPIGLVLELADL--GDLRSYLRQQA | ..| | ||.|.|.. .. .||.| . . .. | ..|. .| ..|.|. | .| . .|.|..| |||..|.... YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG GS-----LSDDAK------ITSGLRHVHDCDLVHRDLASRNVLLFRRTHAVPLAKLGDFGLSRYLSKDHDYYKTAQLDDMPFRWLSPEALRRGNFTF-AS . .. | ..| . |. .|||| |.|| . |..||||.| | ...|| | ... .. RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKC DIWSLGVTLWEIYNEGKTPYGARTLQMIIEMLNTDARLSLSQFPESLAHLVSKIESARAK----------------TSFF |.||.|..|.| . |..|. ..||..... .... ....|. . .| DWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF |
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| Kinase | FGTK4.AA | CTKA | 1386-1474 | 44 | 4e-29 | 94.9 | In-house | 151-235 (290) | Show / Hide |
Range on Protein: 1386-1474 Range on HMM: 151-235/290 Sequence Identity: 44% (40 aa) DLVHRDLASRNVLLFRRTHAVPLAKLGDFGLSRYLSKDHDYYKTAQLDDMPFRWLSPEALRRGNFTFASDIWSLGVTLWEIYNEGKTPY ..|||||| ||.|| . . |. |||..| |. || ||.|| .||||. | |. |||.|. || |||| |..|. GFVHRDLACRNCLLGQ----YCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPW |
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| Kinase | FGTK4.AA | Pkinase | 1269-1508 | 20 | 9.8e-27 | 95.61 | Pfam | 1-273 (293) | Show / Hide |
Range on Protein: 1269-1508 Range on HMM: 1-273/293 Sequence Identity: 20% (58 aa) LAIKAPLGAGNFGTVFKATVVRHREQFNHASVVALKTFDAVEAMDYKAVM----MEAALLHTACDHTHVVRLLAVVDDSVPIGLVLELADLG----DLRS . |. ..|.|.||.|.|.. . .. .||.|... ... . | . .|..... .| ..|||. .. |. | .|.|... | || . YHIGRKIGSGSFGCVYKCHHKGTGK------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFD YLR-QQAGSL--SDD------AKITSGLRHVHDCDLVHRDLASRNVLLFRRTHAVPLAKLGDFGLSRYLSKDHDYYKTAQLDDMP--FRWLSPEALR-RG |.. .. |.. |.. | .|| . |.. .|||| . |.|. .. | . |..||||.. .. | . ... ....|| .| . YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQ NFTFASDIWSLGVTLWEIYNEGKTPYGAR-------TLQMIIEMLNTDARLSLSQF--------------------PESLAHLVSKI . ..|.||.|..|.| .. |..|. . .||| . . .. . . .. .|.. ...... YYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC |
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| Kinase | FGTK4.AA | RTKF | 1269-1369 | 23 | 1.9e-11 | 32.85 | In-house | 1-102 (272) | Show / Hide |
Range on Protein: 1269-1369 Range on HMM: 1-102/272 Sequence Identity: 23% (25 aa) LAIKAPLGAGNFGTVFKATVVRHREQFNHASVVALKTFDAVEAMDYKAVMM-EAALLHTACDHTHVVRLLAVV-----DDSVPIGLVLELADLGDLRSYL . . ||.|.||.| .. . | . .|| |. |. . | |. .. . .| |.... .. .... .|.| | ||.|.|| IMLGEQLGHGHFGRVHHGYWRQQKGQ---RQPVAIKHIHTQDMMNWRRQMLRECCAMNRVGQHPHIIQFFGILMTPFEQNEM--AFVMEFAPHGDMRRYL RQQAGSL | . | QQHDVDL |
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| Kinase | FGTK4.AA | CTKA | 1269-1363 | 31 | 2.6e-09 | 27.31 | In-house | 1-101 (290) | Show / Hide |
Range on Protein: 1269-1363 Range on HMM: 1-101/290 Sequence Identity: 31% (32 aa) LAIKAPLGAGNFGTVFKATVVRHRE----QFNHASVVALKTF--DAVEAMDYKAVMMEAALLH-TACDHTHVVRLLAVVDDSVPIGLVLELADLGDLRSY . | .| | .| ||.| . | ||.| .| |. | .| || .| .| |.||| |. . | . | .|||..| HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKMLKDHATEE-DRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCY LR || LR |
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