Gene FGTK5 (M.brevicollis)
FGTK5
Species: M.brevicollis
Alias: FGTK5
External Links:
Annotation:
Sequence
Protein domains of FGTK5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| FG-GAP | FGTK5.AA | FG-GAP | 63-93 | 21 | 2.1e-05 | 21.47 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 63-93 Range on HMM: 1-35/35 Sequence Identity: 21% (8 aa) GPQTVLAVDVDSDGHTDLVT------ASYYNDQVAWF ....| ..|.. ||..|||. .. . ..| . FGWSVAVGDFNGDGYPDLVVGAPYNGGN-N-GAVYVY |
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| FG-GAP | FGTK5.AA | FG-GAP | 114-144 | 30 | 8e-06 | 22.99 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 114-144 Range on HMM: 1-35/35 Sequence Identity: 30% (11 aa) GSRTLAVADLDNDGDLDLVVG-----SSVDFRISWY . ...||.|...||..||||| .. . ... | FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK5.AA | FG-GAP | 164-193 | 19 | 0.001471 | 15.3 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 164-193 Range on HMM: 1-35/35 Sequence Identity: 19% (7 aa) SIRDVVTADLDNDGYVDIIS------GSNDQNAAIF . | ..|...||| |.. |. . . .. FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK5.AA | FG-GAP | 215-245 | 24 | 0.000195 | 18.25 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 215-245 Range on HMM: 1-35/35 Sequence Identity: 24% (9 aa) AILGVAAADFDNDNLTDVVA------ASESSNTVTWY .||..||..| ..|.|. .. . ..|. | FGWSVAVGDFNGDGYPDLVVGAPYNGGN-N-GAVYVY |
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| Kinase | FGTK5.AA | Ack | 242-253 | 41 | 0.127186 | 1.25 | In-house | 1-12 (266) | Show / Hide |
Range on Protein: 242-253 Range on HMM: 1-12/266 Sequence Identity: 41% (5 aa) VTWYRNLGNGSF .| . ||.|.| ITLCEKLGDGCF |
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| FG-GAP | FGTK5.AA | FG-GAP | 266-295 | 27 | 2e-05 | 21.56 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 266-295 Range on HMM: 1-35/35 Sequence Identity: 27% (10 aa) RPVSVVAVDLNQDGRPDILC------STLLGRVIWF . || ..|.|.||.||.. .. |.| . FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK5.AA | FG-GAP | 315-344 | 13 | 0.000579 | 16.66 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 315-344 Range on HMM: 1-35/35 Sequence Identity: 13% (5 aa) SSRYATAADLDNDGWLDVII------AGYDNNVTAW . ....|...|| .|... .. ...|. . FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK5.AA | FG-GAP | 366-385 | 35 | 0.006249 | 13.19 | Pfam | 1-20 (35) | Show / Hide |
Range on Protein: 366-385 Range on HMM: 1-20/35 Sequence Identity: 35% (7 aa) GAHWIATADFDGDGRTDVAA . . .|..||.|||..|... FGWSVAVGDFNGDGYPDLVV |
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| FG-GAP | FGTK5.AA | FG-GAP | 417-447 | 18 | 0.000267 | 17.79 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 417-447 Range on HMM: 1-35/35 Sequence Identity: 18% (7 aa) GTKALVAVDLDGDGHLDVAS------ANYHGDSLTWY .. .. ..|..|||..|.. .| .... | FGWSVAVGDFNGDGYPDLVVGAPYNGGN-N-GAVYVY |
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| FG-GAP | FGTK5.AA | FG-GAP | 468-498 | 32 | 1.2e-07 | 29.05 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 468-498 Range on HMM: 1-35/35 Sequence Identity: 32% (12 aa) QPTALAAADIDNDGHPDLVS------ANAGHGQVVWY ....|..|...||.|||| .| . |.|. | FGWSVAVGDFNGDGYPDLVVGAPYNGGN-N-GAVYVY |
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| FG-GAP | FGTK5.AA | FG-GAP | 519-548 | 13 | 0.054561 | 10.03 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 519-548 Range on HMM: 1-35/35 Sequence Identity: 13% (5 aa) NTQAIFTVDLDGDADIDVIT------AGPGDATIAW ..... ..|..|| . |... .. ..| . FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK5.AA | FG-GAP | 570-600 | 21 | 0.011271 | 12.33 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 570-600 Range on HMM: 1-35/35 Sequence Identity: 21% (8 aa) GASAVYAADLDNDGLVDVVS------ANSDDAKIAWY . ..| ..|...||. |.| .| . .. | FGWSVAVGDFNGDGYPDLVVGAPYNGGN-N-GAVYVY |
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| FG-GAP | FGTK5.AA | FG-GAP | 620-649 | 25 | 0.000328 | 17.49 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 620-649 Range on HMM: 1-35/35 Sequence Identity: 25% (9 aa) LASAVTVADLDDDGWPDIIC------GGIEGFAQWF ..|.|.|.. || ||.. |. | . FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK5.AA | FG-GAP | 668-696 | 33 | 3.9e-05 | 20.61 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 668-696 Range on HMM: 1-35/35 Sequence Identity: 33% (12 aa) DLRTIAVADMNKDGRLDIVT------SNSF-AVVWY ...||.|.| ||..|.|. .| ||. | FGWSVAVGDFNGDGYPDLVVGAPYNGGN-NGAVYVY |
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| FG-GAP | FGTK5.AA | FG-GAP | 715-746 | 28 | 0.002115 | 14.77 | Pfam | 1-35 (35) | Show / Hide |
Range on Protein: 715-746 Range on HMM: 1-35/35 Sequence Identity: 28% (11 aa) FDQTRAIVADLSGDGYPDVVC------AHFNSSDIRWL | .. |.. |. ||||||.| . | .. . FGWSVAVG-DFNGDGYPDLVVGAPYNGGN-N-GAVYVY |
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| Kinase | FGTK5.AA | FGTK | 847-1133 | 62 | 3e-238 | 797.8 | In-house | 1-302 (302) | Show / Hide |
Range on Protein: 847-1133 Range on HMM: 1-302/302 Sequence Identity: 62% (189 aa) VKDLPVLGKGNFGTVFRVGLNVH--------VALKTFESIQASDYKAVMLEAALLHIACDHPHIVSLIAIVHDSAPISLVLELADLGDLRTYLRHTR--- ..|.|.|||||||||.....|.| ||.|||...|..||||||.||||.|.||||||||.|||.|||..||.||||.||.||||..||... LQDQPPLGKGNFGTVYKAIPNRHREQFQHQVVAVKTFDDVQMMDYKAVMMEAALMHMACDHPHIVQLIAVVHDCMPIALVLEYADHGDLRSFLRQQDAHN ---VLPHTSLVTLGLLHVHECQLVHRDMAARNVLLFRSS-TATPRAKLADFGLSRFISQDCDYYKTTQLTELPFRWMAPEALQRGLFTQASDIWSLGVTI .|......|.||.|||.|||||||||.||||||... .|.|.||||||||||..|.|.|||...||...||||||||||..|.|..|||.||||||| QEMQLQWMAHITSGLCHVHDCQLVHRDMACRNVLLFSRPHMACPQAKLADFGLSRYVSDDHDYYRASQLDDMPFRWMAPEALRHGRFSPASDVWSLGVTI WEMFNEGTTPYGEYTMQMLVELLSVGRRLPVQALPPALASSYASLNCLYFPFAMLGTAPWDPHVLLPTSCCCWCVLHPRLLLKMWSTAAQERPPTRAIVD ||.||.|.|||||.||||..|.|..|.||.....||||...|...||||||||||||||||||||||||||||||||||||..||......||..|..|. WEIFNQGQTPYGERTMQMILEFLQSGQRLDLSHIPPALHHLYMTRNCLYFPFAMLGTAPWDPHVLLPTSCCCWCVLHPRLLTQMWHANPERRPSAREVVH AL || AL |
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| Kinase | FGTK5.AA | TK | 847-1133 | 17 | 3.2e-78 | 261.68 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 847-1133
Range on HMM: 1-486/486
Sequence Identity: 17% (90 aa)
VKDLPVLGKGNFG---TVFRV----------------------------GLNVHVALKTFE---SIQASDYKA--------------VMLEAALLHI-AC
.. . .||.|.|| .|.. | .. || |. . .. . .. ..|..... ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
DHPHIVSLIAIVHDS------------APISLVLELADLGD----LRTYLRHTR----------------------------------------------
.||.||.|....... |. .|.|....|| ||.||| |
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
----------VLPHTSLVT-------------------------LGLLHVHEC------QLVHRDMAARNVLLFRSSTAT-------PRAKLADFG----
|... |. |. . |.. ..|||| ||||.|.... . . | .|.||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ
----LSRFISQD-----------------------CDYYKTTQLTELPFRWMAPEALQ---------RGLFTQASDIWSLGVTIWEMFNEG-TTPYGEYT
|.| | .| |||. .. . ||.||||||.|. | || .||.||.||..||.| | ...||. .
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS
M---------QMLVELLSVGRRL----------PVQALPPALASSYASLNCLYFPFAMLGTAPWDPHVLLPTSCCCWCVLHPRLLLKMWSTAAQERPPTR
| ..|.| |.|| . .|....... . . . ..|.. .. .|... |. ...|| .
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWM-R-----------------YRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFS
AIVDAL
.....|
QLHEQL
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| Kinase | FGTK5.AA | UTK | 847-1061 | 28 | 4.3e-59 | 200.8 | In-house | 1-262 (296) | Show / Hide |
Range on Protein: 847-1061 Range on HMM: 1-262/296 Sequence Identity: 28% (75 aa) VKDLPVLGKGNFGTVFRVGLN--------VHVALKTFE----SIQASD-YKA-VMLEAA---LLHIACD-HPHIVSLIAIVHDSAPISLVLELADLGDLR |. . ||.|.||.|.. .. ..||.|. . |... | . .|.||. .. ... ||... |.... .. |. .|.|.. |||| VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPY-PDFMEEARELQMMK-QFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLR TYLR--------------HTRVLPHTSLVTLGLLHVHECQLVHRDMAARNVLLFRSS---TATPRAKLADFG---LSRFIS--------QDCDYYKTTQL .||| .. | . . . |. . |.|..|||| ||||.|..... . .|.|||| .|| .. .. .||. .. SYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQ TELPFRWMAPEALQRG-LFTQASDIWSLGVTIWEMFNEGTTPYGEYTMQMLVELLSVG--RRLP ...|.|||||||| . ||..||.||.||. ||.. | .||.... . ... .. | .|.| DRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMP |
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| Kinase | FGTK5.AA | Pkinase_Tyr | 847-1061 | 31 | 5e-59 | 200.53 | Pfam | 1-236 (270) | Show / Hide |
Range on Protein: 847-1061
Range on HMM: 1-236/270
Sequence Identity: 31% (75 aa)
VKDLPVLGKGNFGTVFRVGLN-------VHVALKTF-ESIQASD--YKAVMLEAALLHIACDHPHIVSLIAIVH-DSAP--ISLVLELADLGDLRTYLRH
.. . .||.|.||.|.. .. ..|| |. |. .. .. | ||.... ..||.||.|.... .. | | .|.|.. .|||..|||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK
----TRVLPHTSL------VTLGLLHVHECQLVHRDMAARNVLLFRSSTATPRAKLADFGLSRFISQDCDYY-KTTQLTELPFRWMAPEALQRGLFTQAS
. |.. | . |. . .. ...||| ||||.|. . . .| .||||.| | .. ||| .... . || .|||||... | || .|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKS
DIWSLGVTIWEMFNEGTTP-YGEYTMQMLVELL-SVGRRLP
|.|| ||..||.| | .| | . . . ..|.. |.|.|
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMP
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| Kinase | FGTK5.AA | TyrKc | 847-1133 | 26 | 8e-50 | 172.75 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 847-1133 Range on HMM: 1-280/280 Sequence Identity: 26% (85 aa) VKDLPVLGKGNFGTVFRVGLNVHVALKTFESIQASDYKAVMLEAALLHIA-CDHPHIVSLIAIVHDS-------APISLVLELADLGDLRTYLRHTRV-L .. . .|| |.||.|.. ... || |. . .. | || ... .||.|| |.... .. |. .|.|....|||. ||| .| | ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL PHTSLVTL------GLLHVHECQLVHRDMAARNVLLFRSSTATPRAKLADFGLSRFISQD------CDYYKTTQ--LTE--LPFRWMAPEALQRGLFTQA .. |. | . |. ...||| ||||.|. . ..| .||||||.| | |||.... . || ||||||... | || . CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK SDIWSLGVTIWEMFNEGTTPYGE-----YTMQMLVELLSVGRRLPVQAL----PPALASSYASLNCLYFPFAMLGTAPWDPHVLLPTSCCCWCVLHPRLL ||.|| ||..||.| | .|| . . | ..|.. |.|.| . . || .. . SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------------FVCCPDEMYQ-IM LKMWSTAAQERPPTRAIVDAL .. | . .|| ..|.. . KQCWHEDPEDRPTFSEIHECF |
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| Kinase | FGTK5.AA | TK-Unique | 847-1062 | 26 | 2.6e-43 | 147.23 | In-house | 1-260 (294) | Show / Hide |
Range on Protein: 847-1062
Range on HMM: 1-260/294
Sequence Identity: 26% (70 aa)
VKDLPVLGKGNFGTVFRVGLN---------VHVALKTFE-SIQASDYKAVMLEAALLHIACDHPHIVSLIAIVHDSA-PISLVLELADLGDLRTYLRHTR
.. . |.|.|.||.|.| .. ..||.|. . . . | .. . |.... |||.||... . .| | ...| . |.|..||| .|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR
-----------------VLPHTSL---VT------------LGLLHVHE--CQLVHRDMAARNVLLFRSSTATPRAKLADFGLSRFISQDCDYYKTTQLT
. |.. . .. |. . .. .. |||| .|||||| . ..|..|||..| .. . .| ....
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE----DKVCKICDFGMARDVYTNGVYSMMCSQG
ELPFRWMAPEALQ--RGLF-TQASDIWSLGVTIWEMFNEGTTPYGEYTMQMLVELLSVGRRLPV
..| ||||||.|. .| . | ||.||.||..||.| | .||... ..|.. | |.|.
RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQ
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| Kinase | FGTK5.AA | Fer | 847-1044 | 29 | 2.6e-42 | 141.95 | In-house | 1-221 (283) | Show / Hide |
Range on Protein: 847-1044 Range on HMM: 1-221/283 Sequence Identity: 29% (66 aa) VKDLPVLGKGNFGTVFRV----------GLNV---HVALKTF--ESIQASDYKAVMLEAALLHIACDHPHIVSLIAIVHDSAPISLVLELADLGDLRTYL |.. .||.|.||.|.. ...| |. |. |. .. | .| || .. |||..| .. . .| || .|.|... |.|..|| VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL RHTRV--LPH------TSLVTLGLLHVHECQLVHRDMAARNVLLFRSSTA-TPRAK--LADFGLSRFISQDCDYYKTT-QLTELPFRWMAPEALQRGLFT ... .. . . |. . |. . .||| ||||.|. .. | ..|||.|| | . || .. .| ||.|||..| |... KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLY----HKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYS QASDIWSLGVTIWEMFNEGTTPYGE ..|.|| ||..|| |. | .||.. PKTDVWSFGVMCWEIFTNGAEPYPG |
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| Kinase | FGTK5.AA | Ack | 847-1035 | 35 | 3.1e-39 | 129.98 | In-house | 1-205 (266) | Show / Hide |
Range on Protein: 847-1035 Range on HMM: 1-205/266 Sequence Identity: 35% (74 aa) VKDLPVLGKGNFGTVFR------VGLNVHVALKTFESI---QASDYKAVMLEAALLHIACDHPHIVSLIAIVHDSAPISLVLELADLGDLRTYLRHTRVL .. . || | || | | | . || | |. | . |.| .| . ||||.| | .| |. . .| ||| .| | . || ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMH-SLDHPHLVRLYGVVLDQPMLMMVTELAPCGSLLDCLRKHCRT PHTSLVTL---------GLLHVHECQLVHRDMAARNVLLFRSSTATPRAKLADFGLSRFISQDCDYYKTTQLT--ELPFRWMAPEALQRGLFTQASDIWS ..... || |. . . ..||| ||||.|||. .| .||||.| | |||.. .|| |.|||.| . |. |||.|. AFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDD---RKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWM LGVTIWEMF |||.|||| FGVTLWEMF |
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| Kinase | FGTK5.AA | Src | 847-1061 | 31 | 2.9e-38 | 127.59 | In-house | 1-220 (255) | Show / Hide |
Range on Protein: 847-1061 Range on HMM: 1-220/255 Sequence Identity: 31% (72 aa) VKDLPVLGKGNFGTVFR-VGLN-VHVALKTFESIQASDYKAVMLEAALLHIACDHPHIVSLIAIVHDSAPISLVLELADLGDLRTYLR---HTRVLPHTS .| . ||.|.|| |. . . ..|| || . . . .| || .. ..|...|.| |.. . || | |. | | .||. .| |. . IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT-MSPEAFLQEAQIMK-KLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQ LVTL------GLLHVHECQLVHRDMAARNVLLFRSSTATPRAKLADFGLSRFISQDCDYYKTTQLTELPFRWMAPEALQRGLFTQASDIWSLGVTIWEMF |. . | . ...||| |||||| .. .| ||||| | | .| | | . .| .|.||||...| ||. || || |. ..|.. LIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENN----VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIV NEGTTPYGEYTMQMLVELLSVGRRLP | .|| | . .. .. | |.| TYGRVPYPGMTNHEVLQQVERGYRMP |
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| Kinase | FGTK5.AA | TKL | 853-1133 | 17 | 2.8e-36 | 126.84 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 853-1133
Range on HMM: 1-364/364
Sequence Identity: 17% (72 aa)
LGKGNFGTVFRVGLN-----------VHVALKTFESIQ--------------------------ASDYKAVMLEAALLHIACDHPHIVSLIAIVHDSAP-
.|.| ||.|.. .. || |.| | . || .. | ..... ..||.||...... .. .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
------------ISLVLELADLGDLRTYLRHTRVLPHTSLVT------LGLLHVHECQ--------LVHRDMAARNVLLFRSST----------ATPRAK
. .| |... |.|. || . .. .|. . | .. ..||| .|.|... | |. ..|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK
LADFGLSRFISQDCD---------------YYKTTQLTEL-PFRWMAPEALQ----------------RGLFTQASDIWSLGVTIWEMFNEGTTPYGEYT
..|||||||.||. . ...| |. .||||||.|. . .....|..| |. .||.. . || .|
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-PYYDYP
M----------QMLVELLSVGRRLPVQALPPALASSYASLNCLYFPFAMLGTAPWDPHVLLPTSCCCWCVLHP----RLLLKMWSTAAQERPPTRAIVDA
. .|.. . |.|.|. .. .. |.| | .|. . |.. ...|| |..
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQN--------------------------HH--K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKR
L
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L
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| Kinase | FGTK5.AA | RTKA | 952-1078 | 32 | 5.8e-36 | 123.53 | In-house | 161-314 (314) | Show / Hide |
Range on Protein: 952-1078
Range on HMM: 161-314/314
Sequence Identity: 32% (51 aa)
ECQLVHRDMAARNVLLFRSSTATP--RAKLADFGLSRFISQDCDYYKTTQLTELPFRWMAPEALQRGLFTQASDIWSLGVTIWEMFNEGTTPYG------
.| |||| |||||| .. . | ||||||||| ... |||| .. |.||||||||.. . ..|| ||.|| .|| . | ||..
KCGIVHRDVAARNVLVMS---LQPAFHCKLADFGLSRVMPSS-DYYKSRADDEMPFRWMAPECIMERRYSEHSDVWSFGVLVWELLTHGQTPWQNCESHQ
------------------------EYTMQMLVELLSVGRRLPVQALPPALASSYASLNC
. .. .| |..|| . |.... . . |
IVALLMRGERLTFAPTINAALRDSGCDLHHIIQMLKQGQTLPMPPCCPPCLQRFC-FWC
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| Kinase | FGTK5.AA | RTKF | 955-1043 | 57 | 7.9e-35 | 109.44 | In-house | 127-214 (272) | Show / Hide |
Range on Protein: 955-1043 Range on HMM: 127-214/272 Sequence Identity: 57% (52 aa) LVHRDMAARNVLLFRSSTATPR--AKLADFGLSRFISQDCDYYKTTQLTELPFRWMAPEALQRGLFTQASDIWSLGVTIWEMFNEGTTPYG |||||.|||||| | . .|| || |||| | || ||| | ||||||||||| ||| ||.|| |. .|.| | ||| LVHRDVAARNVLVF---EDQPRMYVKLTDFGLARVLSQHQDYYRSMQNEELPFRWMAPEAIMHRRFTQKSDVWSFGMMLFELFTRGDVPYG |
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| Kinase | FGTK5.AA | S_TKc | 847-1135 | 19 | 6.2e-29 | 103.36 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 847-1135
Range on HMM: 1-231/231
Sequence Identity: 19% (60 aa)
VKDLPVLGKGNFGTVFRVGLNV---HVALKTFESIQASDYKAVMLEAALLHIACDHPHIVSLIAIVHDSAPISLVLELADL--GDLRTYLRHTR------
. | ..||| ||.|... . .||.| . .. | ..|. .||.|| |. . .| . .|.|..| |||..|... .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF
-----VLPHTSLVTLGLLHVHECQLVHRDMAARNVLLFRSSTATPRAKLADFGLSRFISQDCDYYKTTQLTELPFRWMAPEALQRGLFTQ-ASDIWSLGV
. . . ..| . |. . .||| |.|| . . |..||||.|.. .| | .|||| | .. ..|.||.|.
PFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-------TTFCGT---PWYMAPEVL---GYGKCKCDWWSCGC
TIWEMFNEGTTPYGEYTMQMLVELLSVGRRLPVQALPPALASSYASLNCLYFPFAMLGTAPWDPHVLLPTSCCCWCVLHPRLLLKMWSTAAQERPPTRAI
...||. | .|. .|||. ... . .. |.. ..|| .
ILYEMLC-GYPPFP--QMQMMFKKIG------------------------------------------------SPEAKD-FIRKCLQKDPEKRPTA-EA
VD-------ALMT
LQDEWDIKCHPWF
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| Kinase | FGTK5.AA | Pkinase | 847-1042 | 23 | 1.9e-23 | 84.02 | Pfam | 1-212 (293) | Show / Hide |
Range on Protein: 847-1042 Range on HMM: 1-212/293 Sequence Identity: 23% (51 aa) VKDLPVLGKGNFGTVFRVGLNVH---VALKTFESIQASDYKAVML----EAALLHIACDHPHIVSLIAIVHDSAPISLVLELADLG----DLRTYLR--- . . ..|.|.||.|.. ||.|... ... | . . |..... .||.|| |. ...|. | .|.|... | || .|.. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR HTRV---LPHTSLVTL----GLLHVHECQLVHRDMAARNVLLFRSSTATPRAKLADFGLSRFISQDCDYYKTTQLTELP--FRWMAPEALQ-RGLFTQAS |... . . . || . |.. .|||. |.|. . . .. |..||||..... | . . .| . ..|||| .. . .... HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV DIWSLGVTIWEMFNEGTTPY |.||.|....||.. | .|. DMWSCGCILYEMLC-GRPPF |
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| Kinase | FGTK5.AA | RTKF | 852-936 | 28 | 3.2e-08 | 22.29 | In-house | 6-100 (272) | Show / Hide |
Range on Protein: 852-936 Range on HMM: 6-100/272 Sequence Identity: 28% (27 aa) VLGKGNFGTVFRV------GLNVHVALKTFESIQASDYKAVML-EAALLHIACDHPHIVSLIAIVH---DSAPISLVLELADLGDLRTYLRHTRV .|| |.||.| . | || |. . . || |. .. .||||. . |. . ...|.| | ||.| || .| QLGHGHFGRVHHGYWRQQKGQRQPVAIKHIHTQDMMNWRRQMLRECCAMNRVGQHPHIIQFFGILMTPFEQNEMAFVMEFAPHGDMRRYLQQHDV |
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| Kinase | FGTK5.AA | RTKA | 847-932 | 24 | 1.6e-05 | 15.5 | In-house | 1-105 (314) | Show / Hide |
Range on Protein: 847-932 Range on HMM: 1-105/314 Sequence Identity: 24% (26 aa) VKDLPVLGKGNFGTVFRVGLNV----------HVALKTFE---SIQASDYKAVMLEAALLHIACDHPHIVSLIAIVHDSAP------ISLVLELADLGDL .. . |.| |.|..| .. | .||.| . . | | |. ||| .|.|||..| .. . ...|.| .. | | MQVRHVVGHGHFSQVYQASLQDMEDEMRQGPQCVAIKECDDLMLNDKTTLSAWMREIMLLHSMRDCPHIIGLHGVCLPREDKHHQSHCGMVCEWCPHGNL RTYLR | .| RDFVR |
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| Kinase | FGTK5.AA | Ack | 1111-1133 | 30 | 0.102558 | 1.57 | In-house | 244-266 (266) | Show / Hide |
Range on Protein: 1111-1133 Range on HMM: 244-266/266 Sequence Identity: 30% (7 aa) LLLKMWSTAAQERPPTRAIVDAL .... | ...|| ||.| | MMMQCWQHHPADRPTFSAIRDQL |
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| Kinase | FGTK5.AA | UTK | 1116-1133 | 33 | 0.114765 | 1.48 | In-house | 279-296 (296) | Show / Hide |
Range on Protein: 1116-1133 Range on HMM: 279-296/296 Sequence Identity: 33% (6 aa) WSTAAQERPPTRAIVDAL | . |||| . .|... WHYDPQERPDFEDLVQQM |
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