Gene LRTK2 (M.brevicollis)

LRTK2

Species: M.brevicollis
Alias: LRTK2
External Links:
Annotation:

Classification

Group: TK
Family: LRTK

Sequence

Name Sequence Type Origin Length Description Download
LRTK2.AA Protein None 868 None Fasta, JSON
LRTK2.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of LRTK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_TYP LRTK2.AA LRR_TYP 175-198 50 0.000119 22.7 SMART 1-24 (24) Show / Hide 
Range on Protein: 175-198
Range on HMM: 1-24/24
Sequence Identity: 50% (12 aa)

LANLTSFDVSNNRITELGVGAFSY
| ||.. | |||..|.|  |||. 
LPNLRELDLSNNQLTHLPPGAFQG
LRR_TYP LRTK2.AA LRR_TYP 223-246 37 0.000631 20.29 SMART 1-24 (24) Show / Hide 
Range on Protein: 223-246
Range on HMM: 1-24/24
Sequence Identity: 37% (9 aa)

LQNLQTLDLSSNPLQTIRTDLLLA
| ||..||||.| |...  ...  
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 LRTK2.AA LRR_1 177-199 29 0.00161 16.65 Pfam 1-26 (26) Show / Hide 
Range on Protein: 177-199
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

NLTSFDVSN-N--RIT-ELGVGAFSYL
||.. |.|. |  ..| ..  ..|  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRTK2.AA LRR_1 225-247 37 0.011005 13.69 Pfam 1-26 (26) Show / Hide 
Range on Protein: 225-247
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLQTLDLSS-N--PLQ-TIRTDLLLAP
|||.||||. |  .|. .|  . . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRTK2.AA LRR_1 201-223 37 0.032978 12.0 Pfam 1-26 (26) Show / Hide 
Range on Protein: 201-223
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RLSHLNLSS-N--RLT-VVTPRDLPML
.| ||.||. |  .||  . |. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP LRTK2.AA LRR_TYP 199-222 37 0.094203 8.26 SMART 1-24 (24) Show / Hide 
Range on Protein: 199-222
Range on HMM: 1-24/24
Sequence Identity: 37% (9 aa)

LMRLSHLNLSSNRLTVVTPRDLPM
|  | .|.||.|.|| . |. .  
LPNLRELDLSNNQLTHLPPGAFQG
Ldl_recept_a LRTK2.AA Ldl_recept_a 342-360 47 2.9e-07 25.02 Pfam 21-41 (41) Show / Hide 
Range on Protein: 342-360
Range on HMM: 21-41/41
Sequence Identity: 47% (10 aa)

HQLCDGHVDCADASDE--QQC
...|||. ||.| |||  ..|
SWVCDGDPDCHDGSDEWPENC
LDLa LRTK2.AA LDLa 321-362 26 1e-05 25.32 SMART 1-47 (47) Show / Hide 
Range on Protein: 321-362
Range on HMM: 1-47/47
Sequence Identity: 26% (14 aa)

SHASH----WPCAAAHGQEPTSLPFHQLCDGHVDCADASDE------QQCEQ
  ...    . |.   |.    .| ...|||. ||.| |||      . |.|
TCPPDHPNQFQCG--NGR---CIPKSWVCDGDNDCGDGSDEWPFFDPENCPQ
Kinase LRTK2.AA LRTK 563-849 50 9.3e-179 600.15 In-house 1-311 (311) Show / Hide 
Range on Protein: 563-849
Range on HMM: 1-311/311
Sequence Identity: 50% (156 aa)

VVDGPTLHRGNFGIVRRG-LICATHEDIVAKCQATGLSQAAILLETTMLML--AQSPNVVGLKG-FLRN-GDLGLMLCLEYCAGGNLLQVLRGSR-ATSS
|....|||||.||.|.|| ..|..|.|.|.||||.......|..|..||.|  .|..|||.|.| |..| ||...|||.|||.||.|||.||..| ....
VHFQHTLHRGTFGAVYRGRAHCFHHQDVVIKCQAHQTECHMIMMELHMLLLQACQHMNVVRLHGVFHQNQGDHHPMLCMEYCCGGSLLQWLRRHRKKWQH

LSPRHLLQASL-QTARALQYLSHLGMIHRDVAARNILVRSVS-----DHGLQAALGDFGHARLVGR----------DSTPS-INQQSSGLG-STVSTVQE
|...|..||.. |.|.|||.|.|.|..||||||||.|.|...     .|..|..|||||||||..|          |.||. .|.||.... ||.|.|.|
LQDEHWMQAIYCQLASALQHLHHCGIVHRDVAARNVLLRHAYVLGSHMHTPQVVLGDFGHARLMHRGTEGSENNPDDGTPMPANMQSFDENDSTPSRVDE

SSPDEYYRQASLIETAARWQPPEVLAQSLFTLASDAWSFGVLLYEIWTLGQVPYGDLVREADVVAAILQNGRRLPVPPRLAELPDRVSKMYQRLQEDVAP
.|..|||||.|.|||||||||||||....|..|||.||.||||||.||.|||||.|..|||||..|||||||.|.|||     . .  |. | .|  .  
ASHGEYYRQQSTIETAARWQPPEVLREQRFSPASDMWSYGVLLYEMWTMGQVPYADVQREADVIRAILQNGRCLHVPPGSRTFVPQLMKRWQSKQPHRPE

RRPGWQAVLRE
.|| |. |...
QRPAWHEVFQH
Kinase LRTK2.AA TK 563-816 18 7.6e-61 202.38 In-house 1-441 (486) Show / Hide 
Range on Protein: 563-816
Range on HMM: 1-441/486
Sequence Identity: 18% (85 aa)

VVDGPTLHRGNFG---IVRRGLICA---------------------------THEDIVAKCQATGLSQAAILL-----------------ETTMLM--LA
.. | .| .|.||    |..|.                              |   .  .   .. ||.. ..                 |  |..  | 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QSPNVVGLKG-FLRNGD----------LGLMLCLEYCAGGN----LLQVLRGSRAT--------------------------------------------
. ||.| | |  ....             .|. .||...|.    |.. || .| .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

---------SSLSPRHLLQ-------------------ASLQTARALQYLSHL------GMIHRDVAARNILVRSVS-------DHGLQAALGDFG----
         ..|. ..|||                    ..| |....||. .      ...|||.||||.|| .         . |... ..|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----HARLVGRD------------------STPSINQQSSGLGSTVSTVQESSP-DEYYRQASLIETAARWQPPEVLAQSL---------FTLASDAWSF
    .|| ...|                  .                   . .| ..||||.|      || .||.|.            || .|| |||
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFE-------------------D-DPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSF

GVLLYEIWTLGQVPYGDLVRE--------ADVVAAILQNG--------------RRLPVPP
|||..||.|.||.||.  .           . |   |..|               |.| ||
GVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPP
Kinase LRTK2.AA UTK 563-820 28 3.4e-51 173.37 In-house 1-269 (296) Show / Hide 
Range on Protein: 563-820
Range on HMM: 1-269/296
Sequence Identity: 28% (82 aa)

VVDGPTLHRGNFGIVRRGLI--CA--THEDIVA--KCQATGLSQAA------ILLETT---MLMLAQ-SPNVVGLKGFLRNGDLGLMLCLEYCAGGNLLQ
|  | .| .|.||.|...    |.    |..||  .||... .| .      ...|..   |..  .  |||..| |   ..   .|. .||...|.|..
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRS

VLRGSRAT-----SSLSPRHLLQASLQTARALQYLSHLGMIHRDVAARNILVRSV----SDHGLQAALGDFG---HARLVG--RDSTPSINQQSSGLGST
.|| .| |      .|. ...|. ... ||..|||.  | .|||.||||.|| .        .......|||    .|.|.  ..|.             
YLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWH-CMMVCKIADFGRGGMSRRVNTFHFSN-------------

VSTVQESSPDEYYRQASLIETAARWQPPEVLAQS-LFTLASDAWSFGVLLYEIWTLGQVPYGDLVREADVVAAILQNG--RRLPVPPRLAE
      .. ..||....  . . ||. ||.|..   ||..|| |||||...|||| |..||...   .. |.. . ||  .|.| |..  .
-----RYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMS--NMQVWHQVCNGGRYRMPCPWDCPH
Kinase LRTK2.AA TyrKc 563-852 24 4.4e-32 113.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 563-852
Range on HMM: 1-280/280
Sequence Identity: 24% (78 aa)

VVDGPTLHRGNFGIVRRGLICATHEDIVAKCQATGLSQAAILLETTMLMLA--QSPNVVGLKGFLRNG------DLGLMLCLEYCAGGNLLQVLRGSRAT
.. | .| .|.||.|..|      ..   |.   .  ..... |  ...    . ||.| | |  . .      .  ||. .||...|.|.. || .| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

SSLSPRHLLQASLQTARALQYLSHLGMIHRDVAARNILVRSVSDHGLQAALGDFGHARLVGRD---STPSINQQSSGLGSTVSTVQESSPDEYYRQAS--
  |....||. ..| |.  .||.. . |||| ||||.||    ......  .||| .| .. |                           ..|||...  
--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLV----GENHTVKISDFGLSRDIYDDDQQG---------------------ESKDYYRKKEHK

LIE--TAARWQPPEVLAQSLFTLASDAWSFGVLLYEIWTLGQVPYGDLV---READVVAAILQNGRRLPVPPR-LAE-----LPDRVSKMYQRLQEDVAP
        || .||..  . || .|| |||||...|| |.|| || . .    ... | . ...|.|.| ||  . .      || . .. ..  .  . 
GGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPE

RRPGWQAVLREHTL
 ||  ...   . .
DRPTFSEI--HECF
Kinase LRTK2.AA TKL 569-831 17 5.7e-25 86.85 In-house 1-345 (364) Show / Hide 
Range on Protein: 569-831
Range on HMM: 1-345/364
Sequence Identity: 17% (65 aa)

LHRGNFGIVRRGLICATH--------EDIVAKCQATG---------------------------LSQAAILLETTMLMLAQ--SPNVVGLKGFLRNGDLG
. .| ||.| .|    .         .|.. |   .                            .|..   .|  ..|. .   ||.| ..|.  ... |
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LMLCLEYCAGGNLLQVLRGSRATSSLSPRHLLQASLQTARALQYLSHLG--------MIHRDVAARNILVRSVSD----------HGL
            |..  ||| ||.|| .|          . .... .|..||...||   .        .||||   .|||| .                
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

QAALGDFGHARLVGRDSTPSINQ------QSSGLGSTVSTVQESSPDEYYRQASLIETAARWQPPEVLAQS----------------LFTLASDAWSFGV
 . ..||| .| . ...  . ..      .            | ..  .  . . .    || .|||| ..                 .. ..| .|||.
CCKICDFGLSRFMSQSGNMNDTMTTMMESA------------E-HQ-NNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGI

LLYEIWTLGQVPYGDLVREADVV-------AAILQNGRRLPVPPRLAE---------LPDRVSKMYQR
.|.|| |  .. |..  .. ..        . . ..|.|.|.||.  .          |....|  |.
VLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQD
Kinase LRTK2.AA Pkinase_Tyr 571-719 28 4.8e-20 68.52 Pfam 9-166 (270) Show / Hide 
Range on Protein: 571-719
Range on HMM: 9-166/270
Sequence Identity: 28% (46 aa)

RGNFGIVRRGLIC----ATHEDIVAKCQ--ATGLSQ---AAILLETTMLMLA-QSPNVVGLKGFLR-NGDL-GLMLCLEYCAGGNLLQVLRGS-RATSSL
.|.|| |..|        |. .   |.    .  .|   .. . |  ...   . ||.| | |     |.   ... .||...|.||  ||       .|
EGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPL

SPRHLLQASLQTARALQYLSHLGMIHRDVAARNILVRSVSDHGLQAALGDFGHARLVGRDST
.. .||| ..| |....||.  ..||||.||||.|| .    ....  .||| ||..  |..
TMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGLARDIYNDDY
Kinase LRTK2.AA S_TKc 563-853 18 1e-19 72.74 SMART 1-231 (231) Show / Hide 
Range on Protein: 563-853
Range on HMM: 1-231/231
Sequence Identity: 18% (57 aa)

VVDGPTLHRGNFGIVRRGLICATHEDIVAKCQATGLSQAAILLETTMLMLAQSPNVVGLKGFLRNGDLGLMLCLEYCAG--GNLLQVLRGSRAT---SSL
   . .. .| || |...    |..    |.         |. |  .|.  . ||.| |... ..    | ...||| |  |.|.....  .     . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

SPRHLLQASLQTARALQYLSHLGMIHRDVAARNILVRSVSDHGLQAALGDFGHARLVGRDSTPSINQQSSGLGSTVSTVQESSPDEYYRQASLIETAARW
.. |      |...||.|.  .| ||||.   |||. .      .  ..||| ||..                                  ... |   .
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL---------------------------------TTFCGTPW-Y

QPPEVLAQSLFTL-ASDAWSFGVLLYEIWTLGQVPYGDLVREADVVAAILQNGRRLPVPPRLAELPDRVSKMYQRLQEDVAPRRPGWQAVLR-E-----H
 .||||    ..  ..| ||.|..|||  . |. |.         ....... .           .. .  . ... .    .||.   .|. |     |
MAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP-------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

TLA
   
PWF
Kinase LRTK2.AA Pkinase_Tyr 741-816 37 2.3e-19 66.21 Pfam 163-239 (270) Show / Hide 
Range on Protein: 741-816
Range on HMM: 163-239/270
Sequence Identity: 37% (29 aa)

PDEYY-RQASLIETAARWQPPEVLAQSLFTLASDAWSFGVLLYEIWTLGQVP-YGDLVREADVVAAILQNGRRLPVPP
.|.|| |...      .| .||... . || .|| ||||||..|| |.|. | | ..   ..|...| ..|.|.| |.
NDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDGYRMPCPE
Kinase LRTK2.AA TK-Unique 563-712 25 5e-19 62.35 In-house 1-181 (294) Show / Hide 
Range on Protein: 563-712
Range on HMM: 1-181/294
Sequence Identity: 25% (47 aa)

VVDGPTLHRGNFGIVRRGLICA-------THEDIVAKCQ--ATGLSQAAILLETTMLMLAQ-SPNVVGLKGFLRNGDLGLMLCLEYCAGGNLLQVLRGSR
.. | ....|.|| | || ..        ..  .| ...  ||...... | |  |..     ||.| . |     |   |. .|||..|||.  || .|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

AT-----------------------SSLSPRHLLQASLQTARALQYLSHLGM--IHRDVAARNILVRSVSDHGLQAALGDFGHAR
 .                       ...||. |..   | |....||. . .  .|||..|||.|. .    .... ..||| ||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE----DKVCKICDFGMAR
Kinase LRTK2.AA RTKF 743-816 39 2.3e-17 52.27 In-house 164-235 (272) Show / Hide 
Range on Protein: 743-816
Range on HMM: 164-235/272
Sequence Identity: 39% (29 aa)

EYYRQASLIETAARWQPPEVLAQSLFTLASDAWSFGVLLYEIWTLGQVPYGDLVREADVVAAILQNGRRLPVPP
.||| ..  | . ||  ||   .  ||  ||.||||..|.|  | | ||||    .. || .   .| .|  |.
DYYRSMQNEELPFRWMAPEAIMHRRFTQKSDVWSFGMMLFELFTRGDVPYGNM--PHPVVLQFIRRGKTLQMPD
Kinase LRTK2.AA RTKA 612-697 28 2.1e-16 54.1 In-house 63-180 (314) Show / Hide 
Range on Protein: 612-697
Range on HMM: 63-180/314
Sequence Identity: 28% (34 aa)

LAQSPNVVGLKG-FLRNGD----LGLMLCLEYCAGGNLLQVLRGSRA-----------TSS---------LSPRHLLQASLQTA-------RALQYLSHL
..  |...|| |  |...|    . . . .|.|  |||. ..| . .             |         ||.  . || ||..        |. ||. .
MRDCPHIIGLHGVCLPREDKHHQSHCGMVCEWCPHGNLRDFVRQHPHFSAPVVATIAMQHSGEPNASPKLLSEAQCHQALLQMCPCWAQVAQAMAYLAKC

GMIHRDVAARNILVRSVS
| .||||||||.|| |..
GIVHRDVAARNVLVMSLQ
Kinase LRTK2.AA TK-Unique 756-816 39 5e-15 48.36 In-house 201-262 (294) Show / Hide 
Range on Protein: 756-816
Range on HMM: 201-262/294
Sequence Identity: 39% (25 aa)

RWQPPEVLA--QSLF-TLASDAWSFGVLLYEIWTLGQVPYGDLVREADVVAAILQNGRRLPVPP
|| .||.|   .  . |  || ||||||..|| |||. ||...  .   .   ...| |.|.|.
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKD--IMECIRDGYRMPQPE
Kinase LRTK2.AA Fer 756-820 27 9.4e-15 46.77 In-house 183-254 (283) Show / Hide 
Range on Protein: 756-820
Range on HMM: 183-254/283
Sequence Identity: 27% (20 aa)

RWQPPEVLAQSLFTLASDAWSFGVLLYEIWTLGQVPYGD-----LVREA--DVVAAILQNGRRLPVPPRLAE
|| .||..   ... ..| |||||...|| | |. ||..      . .   . ...| ..|...| |.. ..
RWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPP
Kinase LRTK2.AA RTKD 756-795 55 9.7e-15 46.51 In-house 171-210 (262) Show / Hide 
Range on Protein: 756-795
Range on HMM: 171-210/262
Sequence Identity: 55% (22 aa)

RWQPPEVLAQSLFTLASDAWSFGVLLYEIWTLGQVPYGDL
|| .||||    |  ||| || .|..||||| .|.|| |.
RWCAPEVLEEHKFSQASDVWSWAVFVYEIWTQAQLPYRDM
Kinase LRTK2.AA RTKE 606-693 33 2.5e-14 45.22 In-house 62-147 (293) Show / Hide 
Range on Protein: 606-693
Range on HMM: 62-147/293
Sequence Identity: 33% (30 aa)

ETTMLMLAQSPNVVGLKGFLRNGDLGLMLCLEYCAGGNLLQVLRGS--RATSSLSPRHLLQASLQTARALQYLSHLGMIHRDVAARNILV
| ||... . ||||.| . .  .. ..|. .||  || | ..|..   | ||  . .| |    | | .. .|  ||..|||..|.|...
EMTMMCKLHHPNVVHLLHVVQMKQ-HFMMVYEYMPGGQLEDWLQDHHGRPTSHEDQIHCLH---QVACGMSFLERLGIVHRDLCAHNVYC
Kinase LRTK2.AA Fer 632-693 33 2.3e-12 38.53 In-house 84-144 (283) Show / Hide 
Range on Protein: 632-693
Range on HMM: 84-144/283
Sequence Identity: 33% (21 aa)

LMLCLEYCAGGNLLQVLRGSRATSSLSPRHLLQASLQTARALQYLSHLGMIHRDVAARNILV
.|...|.| ||.|.  |. . .  ..| . ... ..| |. ..||   ..||||.||||.|.
IMIVMEFCNGGSLDSYLKKNKNK-TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLY
Kinase LRTK2.AA RTKE 731-795 30 1.1e-11 36.09 In-house 162-231 (293) Show / Hide 
Range on Protein: 731-795
Range on HMM: 162-231/293
Sequence Identity: 30% (21 aa)

STVSTVQESSPDEYYRQASLIETA-----ARWQPPEVLAQSLFTLASDAWSFGVLLYEIWTLGQVPYGDL
|.. .. . . ..||| ..    .      ||  |||.  . |. .|| |..|.|..|.|. || || ..
SRDMYLGQEYMQCYYRIKTRRWMPTTWGSRRWWAPEVWKDQHFSFKSDVWAYGCLCWEVWNNGQMPYAHM
Kinase LRTK2.AA RTKF 661-693 52 6.9e-11 31.03 In-house 106-139 (272) Show / Hide 
Range on Protein: 661-693
Range on HMM: 106-139/272
Sequence Identity: 52% (18 aa)

HLLQASLQ-TARALQYLSHLGMIHRDVAARNILV
|.|.|  |  | |. . |  |..||||||||.||
HMLDAAHQVVAEAMVFISRQGLVHRDVAARNVLV
Kinase LRTK2.AA RTKD 670-718 46 2.4e-10 31.4 In-house 113-158 (262) Show / Hide 
Range on Protein: 670-718
Range on HMM: 113-158/262
Sequence Identity: 46% (23 aa)

ARALQYLSHLGMIHRDVAARNILVRSVSDHGLQAALGDFGHAR-LVGRDS
|..| ||.  | .|||.||||||. |     ..| .||||  |  .. ||
AMGLAYLHFRGCCHRDIAARNILLDSN----YRAKIGDFGLTRQQANGDS
Kinase LRTK2.AA RTKA 756-829 25 1e-09 30.34 In-house 213-314 (314) Show / Hide 
Range on Protein: 756-829
Range on HMM: 213-314/314
Sequence Identity: 25% (26 aa)

RWQPPEVLAQSLFTLASDAWSFGVLLYEIWTLGQVPYG------------------------DLVREADV-VAAILQN---GRRLPVPPRLAELPDRVSK
||  || . .  .  .|| ||||||. |. | ||.|..                          .|.... ...| |    |..|| || .  .  |.. 
RWMAPECIMERRYSEHSDVWSFGVLVWELLTHGQTPWQNCESHQIVALLMRGERLTFAPTINAALRDSGCDLHHIIQMLKQGQTLPMPPCCPPCLQRFCF

MY
  
WC
Kinase LRTK2.AA Pkinase 609-721 25 1.4e-07 27.85 Pfam 54-169 (293) Show / Hide 
Range on Protein: 609-721
Range on HMM: 54-169/293
Sequence Identity: 25% (32 aa)

MLMLAQSPNVVGLKGFLRNGDLGLMLCLEYCAGG----NLLQVLRGSRATSSL--SPRHLLQASLQTARALQYLSHLGMIHRDVAARNILVRSVSDHGLQ
|..| ..||.| |... ...|    ...||| ||     |  .... ..  ..  |....    .|..|.|.|.   | ||||.   |||.    |.  .
MKRL-NHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYIST-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILI----DNNGH

A----ALGDFGHARL--VGRDSTPS
      ..||| |..    ..| ..
IDACVKICDFGLAKQFDY-NNS-MT
Kinase LRTK2.AA Pkinase 759-783 38 0.00709 11.25 Pfam 179-204 (293) Show / Hide 
Range on Protein: 759-783
Range on HMM: 179-204/293
Sequence Identity: 38% (10 aa)

PPEVLA-QSLFTLASDAWSFGVLLYE
.|||.  ..  . ..| ||.|..|||
APEVIRGGQYYGPKVDMWSCGCILYE