Gene RTKB4 (M.brevicollis)

RTKB4

Species: M.brevicollis
Alias: RTKB4
External Links:
Annotation:

Classification

Group: TK
Family: RTKB

Sequence

Name Sequence Type Origin Length Description Download
RTKB4.AA Protein None 2068 None Fasta, JSON
RTKB4.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of RTKB4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
NCD3G RTKB4.AA NCD3G 241-267 35 2e-06 21.18 Pfam 27-54 (54) Show / Hide 
Range on Protein: 241-267
Range on HMM: 27-54/54
Sequence Identity: 35% (10 aa)

QCQPCADGTYSSST-MGTCVACADGAES
.| ||..|.||..| . ||. | ..  .
DCIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKB4.AA NCD3G 274-300 37 0.00473 11.03 Pfam 28-54 (54) Show / Hide 
Range on Protein: 274-300
Range on HMM: 28-54/54
Sequence Identity: 37% (10 aa)

CVACTGLEYRNAFNMQTCAACPVGTLP
|. |.. || |  .. ||  || .  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKB4.AA GCC2_GCC3 297-326 29 0.211836 7.52 Pfam 1-31 (49) Show / Hide 
Range on Protein: 297-326
Range on HMM: 1-31/49
Sequence Identity: 29% (9 aa)

GTLPNAERSGCDTCDLGKYRSSAMSF-CAAC
||  |.. . |  |  | |.... .. | .|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPC
GCC2_GCC3 RTKB4.AA GCC2_GCC3 242-274 28 0.423959 6.54 Pfam 11-49 (49) Show / Hide 
Range on Protein: 242-274
Range on HMM: 11-49/49
Sequence Identity: 28% (11 aa)

CQPCADGTYSSSTMGT-CVACADG-----AESSNDRASC
|.||  ||| ..   . | .| .|      . |  . .|
CEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTSESDC
EGF_CA RTKB4.AA EGF_CA 226-242 30 13.143075 1.34 Pfam 31-53 (53) Show / Hide 
Range on Protein: 226-242
Range on HMM: 31-53/53
Sequence Identity: 30% (7 aa)

CE--FCPAG-K---EPNAARTQC
|.   |..| .   |.|. .|.|
CVNQDCMDGYEMISENNCDGTNC
GCC2_GCC3 RTKB4.AA GCC2_GCC3 282-296 33 18.574721 1.2 Pfam 19-33 (49) Show / Hide 
Range on Protein: 282-296
Range on HMM: 19-33/49
Sequence Identity: 33% (5 aa)

YRNAFNMQTCAACPV
|.|  ....| .||.
YQNEEGQDSCIPCPP
GCC2_GCC3 RTKB4.AA GCC2_GCC3 329-370 30 0.00136 14.65 Pfam 1-43 (49) Show / Hide 
Range on Protein: 329-370
Range on HMM: 1-43/49
Sequence Identity: 30% (13 aa)

GTESTGNRASCVACTGLGYRDASSMDQCAACPVG-TTPKADHS
|| . .. . |..|    |.. ...| | .||.| || .  .|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGS
NCD3G RTKB4.AA NCD3G 339-365 25 0.071865 7.52 Pfam 28-54 (54) Show / Hide 
Range on Protein: 339-365
Range on HMM: 28-54/54
Sequence Identity: 25% (7 aa)

CVACTGLGYRDASSMDQCAACPVGTTP
|. |..  | . . ...|  || .  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKB4.AA NCD3G 404-430 29 0.004917 10.98 Pfam 28-54 (54) Show / Hide 
Range on Protein: 404-430
Range on HMM: 28-54/54
Sequence Identity: 29% (8 aa)

CVPCTGVKYRDASSMNQCATCPVGSEP
|.||..  | . . . .| .|| .  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKB4.AA GCC2_GCC3 427-459 32 0.011624 11.62 Pfam 1-34 (49) Show / Hide 
Range on Protein: 427-459
Range on HMM: 1-34/49
Sequence Identity: 32% (11 aa)

GSEPNAERSSCDTCNLGTYRSSAMNA-CAACPVG
|   |.. . |  |  |||.... .  | .||.|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPG
VSP RTKB4.AA VSP 388-405 33 0.019965 9.29 Pfam 300-317 (412) Show / Hide 
Range on Protein: 388-405
Range on HMM: 300-317/412
Sequence Identity: 33% (6 aa)

CAACADGTEPSGDRTSCV
|..| .. ..| |.| |.
CDECFPMYKLSADKTKCP
GCC2_GCC3 RTKB4.AA GCC2_GCC3 378-421 30 0.543174 6.19 Pfam 1-49 (49) Show / Hide 
Range on Protein: 378-421
Range on HMM: 1-49/49
Sequence Identity: 30% (15 aa)

GTYRSAGMGACAACADGT-EPSGDRTSCVPCTGV-K---YRDASSMNQC
||| ..| . | .|  ||  ......|| || .  .   |  ..| ..|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTSESDC
EGF_CA RTKB4.AA EGF_CA 420-437 25 0.606863 5.54 Pfam 30-53 (53) Show / Hide 
Range on Protein: 420-437
Range on HMM: 30-53/53
Sequence Identity: 25% (6 aa)

QCA--TCPVGSE----PNAERSSC
.|    |. | |    .|...  |
ECVNQDCMDGYEMISENNCDGTNC
VSP RTKB4.AA VSP 437-456 45 2.011553 1.91 Pfam 98-115 (412) Show / Hide 
Range on Protein: 437-456
Range on HMM: 98-115/412
Sequence Identity: 45% (9 aa)

CDTCNLGTYRSSAMNACAAC
|.||| |.|...   ||..|
CQTCNDGFYKNG--DACSPC
NCD3G RTKB4.AA NCD3G 437-462 29 2.030038 3.21 Pfam 28-54 (54) Show / Hide 
Range on Protein: 437-462
Range on HMM: 28-54/54
Sequence Identity: 29% (8 aa)

CDTCNLGTYRSSA-MNACAACPVGSEP
|  |  |.| ..  .  |  || .  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
EGF_CA RTKB4.AA EGF_CA 453-469 26 3.41705 3.18 Pfam 31-53 (53) Show / Hide 
Range on Protein: 453-469
Range on HMM: 31-53/53
Sequence Identity: 26% (6 aa)

CA--ACPVGSE----PNAGRSGC
|   .|. | |    .|...  |
CVNQDCMDGYEMISENNCDGTNC
NCD3G RTKB4.AA NCD3G 372-397 25 3.687272 2.44 Pfam 28-54 (54) Show / Hide 
Range on Protein: 372-397
Range on HMM: 28-54/54
Sequence Identity: 25% (7 aa)

CYICNPGTYRS-AGMGACAACADGTEP
|  | .|.| .  ..  |  | ..  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKB4.AA NCD3G 696-722 37 0.000239 14.88 Pfam 28-54 (54) Show / Hide 
Range on Protein: 696-722
Range on HMM: 28-54/54
Sequence Identity: 37% (10 aa)

CAPCAGAEYRQASSMNQCMTCPAGQGP
| ||.. ||   . . .|..|| .| |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKB4.AA NCD3G 566-592 33 0.000565 13.77 Pfam 28-54 (54) Show / Hide 
Range on Protein: 566-592
Range on HMM: 28-54/54
Sequence Identity: 33% (9 aa)

CVPCRGSEYRDASSMNQCAACPVGSEP
|.|| . || . . . .|  || .  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKB4.AA NCD3G 501-527 33 0.000719 13.46 Pfam 28-54 (54) Show / Hide 
Range on Protein: 501-527
Range on HMM: 28-54/54
Sequence Identity: 33% (9 aa)

CVPCTGVEYRDASSMHQCAACPVGSEP
|.||.. || . . . .|  || .  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
NCD3G RTKB4.AA NCD3G 631-657 29 0.006449 10.63 Pfam 28-54 (54) Show / Hide 
Range on Protein: 631-657
Range on HMM: 28-54/54
Sequence Identity: 29% (8 aa)

CVPCSGAGYRDASSMDQCATCPVGSEP
|.|| .  | . . ...| .|| .  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKB4.AA GCC2_GCC3 605-648 32 0.027768 10.39 Pfam 1-49 (49) Show / Hide 
Range on Protein: 605-648
Range on HMM: 1-49/49
Sequence Identity: 32% (16 aa)

GSYRSAGMNECAVCADGT-EPSGNQASCVPCSGA-G---YRDASSMDQC
| | ..| |.|  |  ||  ....| || ||..  .   |  ..| ..|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTSESDC
VSP RTKB4.AA VSP 485-502 33 0.043337 8.05 Pfam 1-18 (412) Show / Hide 
Range on Protein: 485-502
Range on HMM: 1-18/412
Sequence Identity: 33% (6 aa)

CAVCADGTEPSGDRTSCV
|. | .. ..| |.| |.
CDECFPMYKLSADKTKCP
GCC2_GCC3 RTKB4.AA GCC2_GCC3 556-589 32 0.066335 9.16 Pfam 1-34 (49) Show / Hide 
Range on Protein: 556-589
Range on HMM: 1-34/49
Sequence Identity: 32% (11 aa)

GTEPAGNQASCVPCRGSEYRDASSMNQCAACPVG
||   ..|. |.||    |.. ...  | .||.|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPG
NCD3G RTKB4.AA NCD3G 599-624 25 0.092815 7.19 Pfam 28-54 (54) Show / Hide 
Range on Protein: 599-624
Range on HMM: 28-54/54
Sequence Identity: 25% (7 aa)

CDTCAAGSYRS-AGMNECAVCADGTEP
|  |..|.| .  .. .|  | ..  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
GCC2_GCC3 RTKB4.AA GCC2_GCC3 654-696 24 0.235571 7.37 Pfam 1-49 (49) Show / Hide 
Range on Protein: 654-696
Range on HMM: 1-49/49
Sequence Identity: 24% (12 aa)

GSEPNTERSDCGSCDLGTYRTAVMDA-CVVCADG-T----ESARDRASC
|   |.. . | .|  |||.  .    |  | .| |    . .. . .|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTSESDC
NCD3G RTKB4.AA NCD3G 534-559 25 0.323327 5.58 Pfam 28-54 (54) Show / Hide 
Range on Protein: 534-559
Range on HMM: 28-54/54
Sequence Identity: 25% (7 aa)

CDTCAAGSYRS-NGMSACAVCADGTEP
|  |..|.| .  ..  |  | ..  |
CIPCPEGEYSNTTDSYTCTPCPEDQWP
EGF_CA RTKB4.AA EGF_CA 517-534 25 0.494353 5.82 Pfam 30-53 (53) Show / Hide 
Range on Protein: 517-534
Range on HMM: 30-53/53
Sequence Identity: 25% (6 aa)

QCA--ACPVGSE----PNPNHNSC
.|   .|. | |    .|.. . |
ECVNQDCMDGYEMISENNCDGTNC
EGF_CA RTKB4.AA EGF_CA 647-664 25 1.780784 4.07 Pfam 30-53 (53) Show / Hide 
Range on Protein: 647-664
Range on HMM: 30-53/53
Sequence Identity: 25% (6 aa)

QCA--TCPVGSE----PNTERSDC
.|    |. | |    .|...  |
ECVNQDCMDGYEMISENNCDGTNC
EGF_CA RTKB4.AA EGF_CA 582-599 25 6.320704 2.34 Pfam 30-53 (53) Show / Hide 
Range on Protein: 582-599
Range on HMM: 30-53/53
Sequence Identity: 25% (6 aa)

QCA--ACPVGSE----PNSERSGC
.|   .|. | |    .| ..  |
ECVNQDCMDGYEMISENNCDGTNC
GCC2_GCC3 RTKB4.AA GCC2_GCC3 491-524 29 9.825445 2.1 Pfam 1-34 (49) Show / Hide 
Range on Protein: 491-524
Range on HMM: 1-34/49
Sequence Identity: 29% (10 aa)

GTEPSGDRTSCVPCTGVEYRDASSMHQCAACPVG
||  ..    |.||    |.. ...  | .||.|
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPPG
NCD3G RTKB4.AA NCD3G 663-689 25 14.53457 0.67 Pfam 27-54 (54) Show / Hide 
Range on Protein: 663-689
Range on HMM: 27-54/54
Sequence Identity: 25% (7 aa)

DCGSCDLGTYRTAV-MDACVVCADGTES
||  |. |.|     .. |. | ..  .
DCIPCPEGEYSNTTDSYTCTPCPEDQWP
CCP RTKB4.AA CCP 732-784 20 2.5e-07 31.59 SMART 1-79 (79) Show / Hide 
Range on Protein: 732-784
Range on HMM: 1-79/79
Sequence Identity: 20% (17 aa)

CNYLP----ATNAQSNDTA----------AAYGDTLAFSCPAGTYLDG-----------PAILTCMVSGTFNAEP----PVC
|  .|      |.. . .             ||||. .||. | .| |           ....||. .   . .|    | |
CP-PPPHIDPENGYVTCSNSQFTSTFKDTYSYGDTVTYSCNPGYTLIGGRQPEKSQEYHSSTITCQNN--WSPPPWGPLPTC
Sushi RTKB4.AA Sushi 729-784 16 0.000256 18.17 Pfam 1-65 (65) Show / Hide 
Range on Protein: 729-784
Range on HMM: 1-65/65
Sequence Identity: 16% (11 aa)

CG-SCNY--LPAT-NAQSND-----TAAAYGDTLAFSCPAGTYLDGP--AILTCMVSGTFNAEPPV-C
|.  .    .| . . ...      .   .|... ..| .| ...|.  ...||  .|. . ..|. |
CPFDPPDPNIPHGHVIHTTKWRCYRN-YQFGSKVYYECDPGYQMMGQGSNTITC--NGQWTPPFPTPC
GCC2_GCC3 RTKB4.AA GCC2_GCC3 784-819 32 0.219469 7.47 Pfam 11-45 (49) Show / Hide 
Range on Protein: 784-819
Range on HMM: 11-45/49
Sequence Identity: 32% (12 aa)

CVPCPVNTAQIQGNHTDATCQPCAAH-MGTASEGSSA
|.||| .| | ... .  .| || .. . |...||..
CEPCPRGTYQNEEGQD--SCIPCPPGKTTTDYPGSTS
EGF_CA RTKB4.AA EGF_CA 1091-1133 26 9.4e-09 30.09 Pfam 1-53 (53) Show / Hide 
Range on Protein: 1091-1133
Range on HMM: 1-53/53
Sequence Identity: 26% (14 aa)

DIDECLAAG-PGC---SDDSTCVNAEGGFACE---CNDASL---QYNAILHAC
|.|||   .   |   ... .|.| .|.| |.   | |        |.  ..|
DVDECADGTHHMCGDPHRNTWCINTIGSFECVNQDCMDGYEMISENNCDGTNC
EGF_CA RTKB4.AA EGF_CA 1091-1134 27 8.2e-07 29.65 SMART 1-34 (34) Show / Hide 
Range on Protein: 1091-1134
Range on HMM: 1-34/34
Sequence Identity: 27% (13 aa)

DIDECLAAGPGCSDDS---TCVNAEGGFACECNDASLQYNAILHACV
|||||      |.  .   ||.| .|.. | | .   .     . |.
DIDEC-----PCQNGGPTGTCIN-PGSYRC-CPP-GYT-----RHCE
EGF RTKB4.AA EGF 1095-1119 36 0.025493 10.82 Pfam 1-25 (36) Show / Hide 
Range on Protein: 1095-1119
Range on HMM: 1-25/36
Sequence Identity: 36% (9 aa)

CLAAGPGCSDDSTCVNAEGGFACEC
|   . .|. . |||. .||. |.|
CNPNNNPCHHHGTCVDTPGGYTCQC
EGF RTKB4.AA EGF 1094-1134 17 0.103795 8.53 SMART 1-32 (32) Show / Hide 
Range on Protein: 1094-1134
Range on HMM: 1-32/32
Sequence Identity: 17% (8 aa)

ECLAAGPGCSDDS-----TCVNAEGGFACECN-DASLQYNAILHACV
||.    .|. .      ||.    .. | |  .           |.
ECA----PCHHGGCEQHGTCI----SYTC-CPGPGYTG------RCE
EGF RTKB4.AA EGF 1210-1221 33 7.996881 2.48 Pfam 22-36 (36) Show / Hide 
Range on Protein: 1210-1221
Range on HMM: 22-36/36
Sequence Identity: 33% (5 aa)

SCMCSTG---YSGDA
.| |  |   |.|. 
TCQCPPGYLGYTGKR
EGF_2 RTKB4.AA EGF_2 1192-1220 24 24.368859 1.42 Pfam 1-27 (29) Show / Hide 
Range on Protein: 1192-1220
Range on HMM: 1-27/29
Sequence Identity: 24% (8 aa)

CVAPNSNCTV-SGPSDS--IVSCMCSTG-YSGD
|      |.   |  ..     | |. | ..||
C------CNGHHGTCNNQGCGKCQCDDGWWQGD
EGF RTKB4.AA EGF 1234-1264 33 5.2e-05 19.82 Pfam 1-36 (36) Show / Hide 
Range on Protein: 1234-1264
Range on HMM: 1-36/36
Sequence Identity: 33% (12 aa)

CDPN--PCRFGSECEVSRRGARCKCPAG---LKGNN
|.||  ||  . .|  .. | .|.|| |    .| .
CNPNNNPCHHHGTCVDTPGGYTCQCPPGYLGYTGKR
EGF RTKB4.AA EGF 1233-1266 27 0.000279 21.47 SMART 1-32 (32) Show / Hide 
Range on Protein: 1233-1266
Range on HMM: 1-32/32
Sequence Identity: 27% (11 aa)

FCDPNPCRFGS-----ECEVSRRGARCKCP-AGLKGNNCA
 |.  ||  |      .|     . .| || .| .| .| 
ECA--PCHHGGCEQHGTCI----SYTC-CPGPGYTG-RCE
EGF_2 RTKB4.AA EGF_2 1234-1265 25 37.327238 0.84 Pfam 1-29 (29) Show / Hide 
Range on Protein: 1234-1265
Range on HMM: 1-29/29
Sequence Identity: 25% (9 aa)

CDPNPCRF-GSECEVSRRG-ARCKCPAG-LKGNNC
|    |   .  |. .  |  .|.|. |   |. |
C----CNGHHGTCNNQ--GCGKCQCDDGWWQGDHC
EGF RTKB4.AA EGF 1271-1312 27 8.9e-05 23.12 SMART 1-32 (32) Show / Hide 
Range on Protein: 1271-1312
Range on HMM: 1-32/32
Sequence Identity: 27% (13 aa)

ACNGRCNGR-----GTCTPGAASPDLNPRTSSYVCQCD-RGFSGQDCE
 |   |        |||.             || | |   |..|  ||
ECA-PCHHGGCEQHGTCI-------------SYTC-CPGPGYTG-RCE
EGF_2 RTKB4.AA EGF_2 1272-1311 30 0.000278 16.88 Pfam 1-29 (29) Show / Hide 
Range on Protein: 1272-1311
Range on HMM: 1-29/29
Sequence Identity: 30% (14 aa)

CNGRCNG-RGTCT-PGAASPDLNPRTSSYV---CQCDRG-FSGQDC
|   ||| .|||  .              .   ||||.| ..| .|
C---CNGHHGTCNNQ--------------GCGKCQCDDGWWQGDHC
EGF RTKB4.AA EGF 1272-1310 26 0.000388 16.89 Pfam 1-36 (36) Show / Hide 
Range on Protein: 1272-1310
Range on HMM: 1-36/36
Sequence Identity: 26% (12 aa)

CNG---RCNGRGTCTPGAASPDLNPRTSSYVCQCDRG---FSGQD
||     |...|||...          ..| |||  |   ..| .
CNPNNNPCHHHGTCVDTP---------GGYTCQCPPGYLGYTGKR
EGF_CA RTKB4.AA EGF_CA 1297-1311 23 31.165494 0.16 Pfam 28-53 (53) Show / Hide 
Range on Protein: 1297-1311
Range on HMM: 28-53/53
Sequence Identity: 23% (6 aa)

SYVCQ---CDRGFS--------GQDC
|. |.   |..|..        |  |
SFECVNQDCMDGYEMISENNCDGTNC
Kinase RTKB4.AA RTKB 1389-1651 67 2.8e-202 678.3 In-house 1-264 (264) Show / Hide 
Range on Protein: 1389-1651
Range on HMM: 1-264/264
Sequence Identity: 67% (179 aa)

VRLGEKLGNSASAEVFQAWLRNRHSYGEQSCAAKQLRVQASSTERQAFLSEMTVMKDMGEHPNVIGIVGHCLHDEPPILLVELAELGNLRDYLRECRAPD
|.|||||||.|..||||||.||||...|||||||.|...||..|||.|.|||||||..|.|||||||.||||.|||.||||||.||||||||||.|||..
VWLGEKLGNGAFGEVFQAWVRNRHMNTEQSCAAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIGHCLQDEPYILLVELCELGNLRDYLRMCRASQ

SGPQPLSAAQLLDFCCQIANGMAFLEQKKIVHRDLAARNVLVGQQLSCKISDFGLARALDGEQYETTLDRFPIKWMAPESLARSIYSIKS-DVWAFGVTM
..||.|..|||.|||.|||.|||||.|....||||.||||||.|||.|||.|||.||..|.|.||||..|.|||||||||.|..||..|| |||.|||||
HNPQSLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHECYETTCTRLPIKWMAPESWAHRIYTTKSGDVWSFGVTM

WEVFSMGGTPYQAYQNAQILGLLESGHRLPMPSQAPLKADEIMRQCWSIHAEERPTFSALVSAL
||.||.||||||.|.|..|...||||||||.|.|.| .||.||..||...|..||.|..||.|.
WEIFSLGGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase RTKB4.AA Pkinase_Tyr 1389-1651 38 9.20000000001e-118 399.45 Pfam 1-270 (270) Show / Hide 
Range on Protein: 1389-1651
Range on HMM: 1-270/270
Sequence Identity: 38% (106 aa)

VRLGEKLGNSASAEVFQAWLRNRHSYGEQSCAAKQLRVQASSTE--RQAFLSEMTVMKDMGEHPNVIGIVGHCL-HDEP--PILLVELAELGNLRDYLRE
...|.|||  |  ||... ..  .. ... .| | |. .|.. .  |..|..|. .|| .| |||..  .| |. ..||  ... .|....|.|.||||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

CRAPDSGPQPLSAAQLLDFCCQIANGMAFLEQKKIVHRDLAARNVLVGQQLSCKISDFGLARAL--DGEQ-YETTLDRFPIKWMAPESLARSIYSIKSDV
 |   ...|||.  .||..| |||.||..||.|...||||||||.||. .. .||.||||||..  |..  . ..  ..||||||||... .....||||
HR---EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

WAFGVTMWEVFSMGGTP-YQAYQNAQILGLL-ESGHRLPMPSQAPLKADEIMRQCWSIHAEERPTFSALVSAL
|.|||.|||.|. |..| |.   |.... .. |.|.|.|.|  .| .  ..|.|||   .|.|||||.... |
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase RTKB4.AA TK 1389-1651 22 2.2e-115 388.48 In-house 1-486 (486) Show / Hide 
Range on Protein: 1389-1651
Range on HMM: 1-486/486
Sequence Identity: 22% (112 aa)

VRLGEKLGNSASA---EVFQAWLRNR---------------------HSYGEQSCAAKQLRV--QASSTERQA--------------FLSEMTVMKD-MG
..||.|||  .     ||.....|.|                     .. |.. .| |.|.    .|..|...              ...|| .|.  .|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

EHPNVIGIVGHCLHD------------EPPILLVELAELGN----LRDYLRECRAPDSGPQP--------------------------------------
.|||.. ..|.|...            ||.....|....|.    ||||||.|| . . .|.                                      
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSAAQLLDFCCQIANGMAFLEQK------KIVHRDLAARNVLVGQQLS-----------CKISDFG---
                               |. .||| .|.|||.||..|..|      ..|||||||||.|||...            |||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARALDGEQYETTLD--------------------------RFPIKWMAPESLA---------RSIYSIKSDVWAFGVTMWEVFSMGGTPYQA-Y
     |||... ... .. .                          ..||.|||||.|.           ....|||||.|||.|||.|. | .||    
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

QN---------AQILGLLESG--------------HRLPMPSQAP--------------LKADEIMRQCWSIHAEERPTFSALVSAL
 |         .... .|..|              .|.| | ..|                 ...|.|||.  .|.|||||.|...|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RTKB4.AA TyrKc 1389-1651 34 3.1e-115 390.04 SMART 1-280 (280) Show / Hide 
Range on Protein: 1389-1651
Range on HMM: 1-280/280
Sequence Identity: 34% (103 aa)

VRLGEKLGNSASAEVFQAWLRNRHSYGEQSCAAKQLRVQASSTERQAFLSEMTVMKDMG-EHPNVIGIVGHCLHD-------EPPILLVELAELGNLRDY
..||.|||. |  ||... ..       . .| | |.  |    |..|..|. .|.  | .|||.. ..| |...       ||. ...|....|.|.||
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LRECRAPDSGPQPLSAAQLLDFCCQIANGMAFLEQKKIVHRDLAARNVLVGQQLSCKISDFGLARALDGE-------QYETT----LDR--FPIKWMAPE
||..|        |. ..||.|| |||.||..|..|...||||||||.||| .. .|||||||.|... .       .| ..      .  .||.|||||
LRKHRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

SLARSIYSIKSDVWAFGVTMWEVFSMGGTPYQA-----YQNAQILGLLESGHRLPMPSQ--------APLKADEIMRQCWSIHAEERPTFSALVSAL
..  .....|||||.|||.|||.|. |..||         |.... ....|.|.| |          .| .  .||.|||   .|.|||||.... .
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RTKB4.AA TK-Unique 1389-1651 35 4e-93 315.7 In-house 1-294 (294) Show / Hide 
Range on Protein: 1389-1651
Range on HMM: 1-294/294
Sequence Identity: 35% (105 aa)

VRLGEKLGNSASAEVFQAWLRNRH-SYGEQSCAAKQLRV-QASSTERQAFLSEMTVMKDMGEHPNVIGIVGHCLHD-EPPILLVELAELGNLRDYLRECR
...|...|  |  .|. . ....  . ..|.|.|  ..   |. |..|.||.|  .||  | |||.. ..| |  . ||. .. | .. |||..|||.||
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

APDSGPQ-------------------PLSAAQLLDFCCQIANGMAFLEQ--KKIVHRDLAARNVLVGQQLSCKISDFGLARALD-GEQYETTL--DRFPI
 . ...|                   |.|  .|. |..|||.||..|..  ||||||||.|||||..  . |||.|||.|| .. ...|...    | ||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWMAPESLA--RSIY-SIKSDVWAFGVTMWEVFSMGGTPYQAYQNAQILGLLESGHRLPMPSQA-PLKADEIMRQCWSIHAEERPTFSALVSAL
.|||||||   . .| ..|||||.|||.|||.|..|..||  . ...|. ... |.|.| |..  .    ..|..||.  .||||.|..... |
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase RTKB4.AA UTK 1389-1651 34 3e-92 312.8 In-house 1-296 (296) Show / Hide 
Range on Protein: 1389-1651
Range on HMM: 1-296/296
Sequence Identity: 34% (103 aa)

VRLGEKLGNSASAEVFQAWLRN-RHSYGEQSCAAKQLRVQASSTERQA----FLSEMT---VMKDMGEHPNVIGIVGHCLHDEPPILLVELAELGNLRDY
|.||..||  |  ||. | ... .   .|. .| |.... |...  ..    |. | .   .||   .||||.. || |. .||.....|..| |.||.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRECRA-PDSGPQPLSAAQLLDFCCQIANGMAFLEQKKIVHRDLAARNVLVGQQ-------LSCKISDFG---LARALD---------GEQYETT--LDR
|| .|  |.  |  |.  |.|... .||.||..|.....|||||||||.||...       ..|||.|||   ..|..          . .|..    ||
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

FPIKWMAPESLARS-IYSIKSDVWAFGVTMWEVFSMGGTPYQAYQNAQILGLLESG--HRLPMPSQAPLKADEIMRQCWSIHAEERPTFSALVSAL
 ||.|||||.|.    ...|||||.|||..||....| .||  . |.|..  .. |  .|.| | . |.   ..|..||    .|||.|  ||...
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase RTKB4.AA Src 1389-1651 37 8.8e-82 277.62 In-house 1-255 (255) Show / Hide 
Range on Protein: 1389-1651
Range on HMM: 1-255/255
Sequence Identity: 37% (101 aa)

VRLGEKLGNSASAEVFQAWLRNRHSYGEQSCAAKQLRVQASSTERQAFLSEMTVMKDMGEHPNVIGIVGHCLHDEPPILLV-ELAELGNLRDYLRECRAP
..| .|||.    ||...  ...        | | |.      . .||| |  .|| .  |.... .   |  .| ||. | |. . |.| |||..    
IKLCRKLGQGQFGEVWMGYWNGNT-----KVAVKTLKPGT--MSPEAFLQEAQIMKKL-RHEKLVQLYAVCSQEE-PIYIVTEYMSHGSLLDYLKK----

DSGPQPLSAAQLLDFCCQIANGMAFLEQKKIVHRDLAARNVLVGQQLSCKISDFGLARALD--GEQY-ETTLDRFPIKWMAPESLARSIYSIKSDVWAFG
|.  . |.  ||.|. .|.|.|||.||.....||||||||||||... ||. |||||| ..   . |   .  .|||||.||| . .  ..|||||| ||
DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFG

VTMWEVFSMGGTPYQAYQNAQILGLLESGHRLPMPSQAPLKADE-IMRQCWSIHAEERPTFSALVSAL
. ..|... | .||   .|.. |  .| | |.|.|.. | .  | ||.|||   .|.||||  | . |
ILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase RTKB4.AA KIN6 1432-1651 35 1.3e-75 249.33 In-house 60-305 (305) Show / Hide 
Range on Protein: 1432-1651
Range on HMM: 60-305/305
Sequence Identity: 35% (88 aa)

ERQAFLSEMTVMKDMGEHPNVIGIVGHCLHDEPPILLVELAELGNLRDYLRECR--------------APDSGP--QP---LSAAQLLDFCCQIANGMAF
... |. |   ||  | || ..   |     ..| |.||. . ..|  |||. .               ||  .   .   ..  .|. |  ||..|| .
AHHDFMHEIAFMKQLGHHPHLVNMLGCVTNSYKPCLVVEYCCHMDLLKYLRNRCQYMMNLDDLGINYHCPDENSRYDDMMCIRHKDLYMFAWQICDGMEY

LEQKKIVHRDLAARNVLVGQQL---SCKISDFGLAR--ALDGEQYETTLDR-FPIKWMAPESLARSIYSIKSDVWAFGVTMWEVFSMGGTPYQAYQ-NAQ
| .| ..|||||||||||  ..   .||||||||.|    |  || .  .|  ||||||||.|.   .|.||||| ||| |.|.||.|. ||   |    
LHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMDQFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTE

ILGLLESGHRLPMPSQAPLKADEIMRQCWSIHAEERPTFSALVSAL
..  ..|| |.  |  .| .  .||..||.   ..|| |. .  ..
MIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase RTKB4.AA FGFR 1389-1651 35 2.3e-75 256.34 In-house 1-293 (293) Show / Hide 
Range on Protein: 1389-1651
Range on HMM: 1-293/293
Sequence Identity: 35% (103 aa)

VRLGEKLGNSASAEVFQAWLR---NRHSYGEQSCAAKQLRVQASSTERQAFLSEMTVMKDMGEHPNVIGIVGHCLHDEPPILLVELAELGNLRDYLRECR
  ||. ||  .  .|  |      . .   |   | | |   .. ..     ||| .||  |.|.|.|   | |  . |.  .||... |||||.||. |
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRARR

APD-----SGP-----------QP--------LSAAQLLDFCCQIANGMAFLEQKKIVHRDLAARNVLVGQQLSCKISDFGLARALDGEQY--ETTLDRF
 |      ...           |.        |.  .|  .  |.| || .|. .|..|||||||||||.     ||.||||||      |   ||  | 
PPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNGRL

PIKWMAPESLARSIYSIKSDVWAFGVTMWEVFSMGGTPYQAYQ-NAQILGLLESGHRLPMPSQAPLKADEIMRQCWSIHAEERPTFSALVSAL
||||||||.|   .|  .|||| .|| .||..  ||.||       ..  .| .|||.  |.. ..    .|.|||   ...||||  || .|
PIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase RTKB4.AA Fer 1389-1652 30 2.5e-75 255.96 In-house 1-283 (283) Show / Hide 
Range on Protein: 1389-1652
Range on HMM: 1-283/283
Sequence Identity: 30% (88 aa)

VRLGEKLGNSASAEVFQA--WLRNRHSYGEQ----SCAAKQLRVQASSTE-RQAFLSEMTVMKDMGEHPNVIGIVGHCLHDEPPILLVELAELGNLRDYL
| ||.|||. |  ||...   |.   . . .     .. | ..  ....| .. |. |. .|.    ||||. . | | ...|  .. |..  |.|..||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

RECRAPDSGPQPLSAAQLLDFCCQIANGMAFLEQKKIVHRDLAARNVLVGQ-QLSCK--ISDFGLARALDGEQYETT----LDRFPIKWMAPESLARSIY
..  .       .| ......| |.|.||..|..|...|||.||||.|... .. .|  |||||..|......|  .    ... ||.|.|||..   ||
KKNKNK-----TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIY

SIKSDVWAFGVTMWEVFSMGGTPYQA----YQNAQI-----LGLLESGHRLPMPSQAPLKADEIMR-QCWSIHAEERPTFSALVSALT
| |.|||.|||..||.|. | .|| .     .....         ..|...|||...|    .||  |||  . |.|||.. ..  | 
SPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase RTKB4.AA EGFR 1420-1652 37 3e-70 232.4 In-house 32-258 (258) Show / Hide 
Range on Protein: 1420-1652
Range on HMM: 32-258/258
Sequence Identity: 37% (89 aa)

AAKQLRVQASSTERQAFLSEMTVMKDMGEHPNVIGIVGHCLHDEPPILLVELAELGNLRDYLRECRAPDSGPQPLSAAQLLDFCCQIANGMAFLEQKKIV
| | || | .    ...| |..||  . .||... ..| |.|..   |   .  .|.| ||.|. .        . . .|| .| ||| || .||....|
AIKVLREQTGPKANEEMLDEAYVMASV-DHPHLVRLLGVCMHSQ-MQLVTQYMPYGCLLDYVRQHK------DNIGSQHLLNWCVQIAKGMQYLEEHRMV

HRDLAARNVLVGQQLSCKISDFGLARALDGEQYETTLDR--FPIKWMAPESLARSIYSIKSDVWAFGVTMWEVFSMGGTPYQAYQNAQILGLLESGHRLP
||||||||||| .    || |||||. |. .. | . .    |||||| |.. . .|  .||||..|||.||.   |. ||.  . ..|  ||| | |||
HRDLAARNVLVKSPNHVKITDFGLAKLLEHDEKEYHAQGGKMPIKWMALECIHHRCYTHQSDVWSYGVTCWELMTFGQKPYDGIPAREIPDLLEKGERLP

MPSQAPLKADEIMRQCWSIHAEERPTFSALVSALT
 |    .    .| .|| | .. ||||  |.. . 
QPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase RTKB4.AA RTKJ 1389-1653 37 1.9e-69 237.05 In-house 1-278 (278) Show / Hide 
Range on Protein: 1389-1653
Range on HMM: 1-278/278
Sequence Identity: 37% (105 aa)

VRLGEKLGNSASAEVFQAWLRN--RHSYGEQSCAAKQLR--VQASSTERQAFLSEMTVMKDMGEHPNVIGIVGHCLHDEPPILLVELAELGNLRDYLREC
|  | .||      |    ||       |    | |||.  |   | |   |  ||  | |.| | .|.  || |    |  . .. |. | | ..|| |
VVIGQQLGAGHFGIVSRGLLRKSITDNTGNMDVAVKQLKRDVDVDSDEVDEFFHEMKLMMDLGHHQHVVSLVGVCRREQPILMIIDFANKGDLMHHLRDC

RAPDSGPQPLSAAQLLDFCCQIANGMAFLEQKKIVHRDLAARNVLVGQQL-------SCKISDFGLARAL-DGEQYETTLDR-FPIKWMAPESLARSIYS
|. |     |      |.| ||| || ||  ..|.|||||||||||  .          || ||||.| . . . |  . |   | ||.|.|..   ..|
RPNDRREATLRRDDFFDYCAQIAAGMEFLAFHRIIHRDLAARNVLVHDDGRTEINGYVLKIADFGLTRQARNDDNYRKCEDDAVPFKWLAIECFRDRVFS

IKSDVWAFGVTMWEVFSMGGTPYQAYQNAQILGLLESGHRLPMPSQAPLKADEIMRQCWSIHAEERPTFSALVSALTS
  |||||||.|.||..  |  ||   ||. |   |  |||.| |      . .|| .||   . ||||||.|   .  
QASDVWAFGITCWEIYTFGQSPYPGIQNNEIYDRLVKGHRMPRPFDCSKQMYDIMMHCWKFNPRERPTFSTLLNEISP
Kinase RTKB4.AA S_TKc 1389-1654 20 4.1e-39 137.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 1389-1654
Range on HMM: 1-231/231
Sequence Identity: 20% (57 aa)

VRLGEKLGNSASAEVFQAWLRNRHSYGEQSCAAKQLRVQASSTERQAFLSEMTVMKDMGEHPNVIGIVGHCLHDEPPILLVELAEL--GNLRDYLRECRA
 ....|.|  | ..|.... ..      . .| |...        . ...|. ..|    |||.. . ... . .   .  |...   |.|.||..... 
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

PDSGPQPLSAAQLLDFCCQIANGMAFLEQKKIVHRDLAARNVLVGQQLSCKISDFGLARALDGEQYETTLDRFPIKWMAPESLARSIYSI-KSDVWAFGV
.  ...|..  .   ...||....... ...|.||||   |.|. .    ||.|||||| |       |       .|||| |    |.  |.|.|..|.
HG-LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

TMWEVFSMGGTPYQAYQNAQILGLLESGHRLPMPSQAPLKADEIMRQCWSIHAEERPTFSALVS------ALTSL
...| .. | .|..  | .... ..            .  | ...|.|.    |.|||   .        .   .
ILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RTKB4.AA Pkinase 1389-1651 18 1.1e-21 77.72 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1389-1651
Range on HMM: 1-293/293
Sequence Identity: 18% (57 aa)

VRLGEKLGNSASAEVFQAWLRNRHSYGEQSCAAKQLRVQASST--ERQAFL-SEMTVMKDMGEHPNVIGIVGHCLHDEPPILLVELAELG----NLRDYL
 ..|.|.|  ....|...    .|   ..  | |.....  .   ...... ||  .|| .  |||.. . . .  .  . .  |..| |     | ||.
YHIGRKIGSGSFGCVYKC----HHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

RECRAPDSGPQPL--SAAQLLDFCCQIANGMAFLEQKKIVHRDLAARNVLVGQQLSC----KISDFGLARAL-DGEQYETTLDRFPIKWMAPESLA-RSI
.      .   ..  |  .. ... ||. |.... ...|.||||   |.|. ..  .    ||.|||||. .    .  .|     . .|||| .  .. 
ST-----WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQY

YSIKSDVWAFGVTMWEVFSMGGTPYQAY----QNAQILGLLESGHRLPMPSQAP-----------------------LKADEIMRQCWSIHAEERPTFSA
|. |.|.|..|....|... | .|..        .  . ...   . | ... |                         . .... |.    ..|||.  
YGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQ

LVSA--L
..    .
ILQHPWF