Gene RTKK2 (M.brevicollis)

RTKK2

Species: M.brevicollis
Alias: RTKK2
External Links:
Annotation:

Classification

Group: TK
Family: RTKK

Sequence

Name Sequence Type Origin Length Description Download
RTKK2.AA Protein None 3231 None Fasta, JSON
RTKK2.kin_dom Protein Kinase Domain None 271 None Fasta, JSON

Protein domain

Protein domains of RTKK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
MFS_1 RTKK2.AA MFS_1 14-409 13 1.8e-27 99.8 Pfam 1-370 (370) Show / Hide 
Range on Protein: 14-409
Range on HMM: 1-370/370
Sequence Identity: 13% (59 aa)

LYFTQCLAFCCVTFFTVYFQ-AQGLDLH---HVGIIMGGIYPTTQMVAQPLWCQLADRLAAPKAIILISLVLGLIG-IGSLMY--A--ENFF-QLALFTG
|.|....|.  .... . .  . . |..   ..  .| ..|  .. ..||.|  ..||. . . ...|...| .|| .. ...  |   |.. .|...  
LFFCYFCAYMGWWMIWPALPWYMAEDFGWSPTQIGWMMTAYFLGYAIFQPPWGWWSDRFGRRR-VMIIGMILWAIGCLCLFPFAPAATHNWWWMLMVLRF

IGAALGAAANPLLDATTMQTLLDNDVTLDNYGKYRVWGAVGYGVSAVIMGPLMDAFG--LDMLFYCLAGFTAVFFL-CVLVFPFRTDANAHLRPEQTAAV
. .. |....|.  | ..    . .. . . | . .   .|. . ....| |.|..|     .|. ........|. ..... .|... .   ..  .. 
LQGFGGGMFWPAMMAMIADWFPPEERGRAM-GIWSAGFNLGPMIGPPLGGWLADWWGWGWRWVFWIMGIICLIWFVCLWAWWFWRPPP-P-RPKP-EEW-

PASVKDEKEPLLQKAPAGPVEDWHEGVASVNHQAAVANENEQPCANSNLPPRKLSICE-YLHALAQQP---------TVGLFFLLVVLMGTGKGAVDTYL
                                                  ... .. .  . .|  .|         .. .||.  .....  . . ..|
--------------------------------------------------WAH-PWVPGAWKHLFRNPVFILRLWGMLWIAFFCFFMCFFGV-N-FFFWL

FLY--LEDMGATKTLLGISLGVTTISELPFFFYSGYMLKR----WGTISVITLALFAYAARLGYYGTLQHPWLVLP--AELL--HGI-TFGLSWAAMASH
.||  .|..| . .|.|. .|.  |  ..... .|....|    . .. .. ..... |. . . . ....|...   | ..   |. .||. ...... 
PLYMLQEVFGWS-MLAGFMFGICGIIGIIGRPFWGWLSDRVWGRRRRWLMGCGGAILCAFGFMWFSFTHSYWWFWWLAAMFIMVWGFFGFGMVFPTWNTL

AAAIA-PRGYTSSTQALASAAFFGLGFAIAP
..  | |......  .|.. ....|| ||.|
VMDHAAPPHHRGTAMGLYN-MCWQLGGAIGP
Kinase RTKK2.AA RTKK 2939-3209 73 3.8e-235 787.49 In-house 1-272 (272) Show / Hide 
Range on Protein: 2939-3209
Range on HMM: 1-272/272
Sequence Identity: 73% (201 aa)

IEIQRTLGSGQFGVVFQAQVRKNGQLLTAAVKKAVVGETEEVSRQLNIDLLAEAYLLMLAKPHDHVVGLLG-FHLAGSSVLVALDFAKGGDLESYLASLA
||||||.||||||.|.||||||..|.||||.|...|....||.||.|.|||.||||||.||||||||.|.| ||..||||....|.||.|||..||...|
IEIQRTIGSGQFGIVYQAQVRKRDQWLTAAIKQPHVENPDEVDRQVNKDLLVEAYLLMYAKPHDHVVTLYGCFHMTGSSVAMVMDMAKHGDLRMYLRQGA

ARDAQVRFESTVMVWYALIPXQIASGLAHLHAVGIVHRDVATRNVLLKSSKPLHLVLTDLGLARAINESIYYKQTSKTAVPFPWMSPESLINRRSSPASD
.|..||||...||||||||| |||.||.||||..|||||||.||||..||.|||.|.|||||||.|.|.||||||||.|||||||||||||.||.|||||
KRQSQVRFDKMVMVWYALIPAQIAQGLSHLHAKHIVHRDVACRNVLVMSSQPLHIVITDLGLARTIREQIYYKQTSKVAVPFPWMSPESLIHRRFSPASD

VWSLGVTAWEICSNGARPWGGMEPQDIVLAVHRGQRLAISNNWPEQIQSLLRSSWELDTNLRPSARDYVSKL
|||||.|||||||||.|||.|||||||.||||||||..|.||||.|||||||..||.|.|.|||||||||||
VWSLGMTAWEICSNGQRPWEGMEPQDIMLAVHRGQRPVIQNNWPPQIQSLLRRVWERDPNKRPSARDYVSKL
Kinase RTKK2.AA TK 2939-3209 17 2.2e-73 245.18 In-house 1-486 (486) Show / Hide 
Range on Protein: 2939-3209
Range on HMM: 1-486/486
Sequence Identity: 17% (84 aa)

IEIQRTLGSGQFG---VVFQAQVR-----------------------KNGQLLTAAVKKAVVGETEEVSRQLN--ID----------LLAEAYLLML-AK
|.. ..||.||||   .|.....|                       |.|.  . |||    | ...  ...   ..          ...|. .... . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

PHDHVVGLLG-------------FHLAGSSVLVALDFAKGGD----LESYLASLAA--------------------------------------------
 |...| |.|             . ...  ... . ....||    | .|| .                                               
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

------RDAQVRFESTVMVWYAL----------------IPXQIASGLAHLHAV------GIVHRDVATRNVLLKSSKP---------LHLVLTDLG---
      .|.   .  . .. .|.                .  |||.|...||.       ..||||.|.||.|. ....         ..  ..| |   
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARAINE------------------------SIYYKQTSKTAVPFPWMSPESLI---------NRRSSPASDVWSLGVTAWEICSNGARPWGG-M
     |||.|..                        . ||.|.|.. .|. ||.||.|          ... ...|||||.||. |||...|. |..| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

EP---------QDIVLAVHRGQRL-----------------AISNNWP-----------EQIQSLLRSSWELDTNLRPSARDYVSKL
           |...  . ||.||                 .    |.           | .. |... |..| . ||. .. ...|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RTKK2.AA UTK 2939-3209 27 2.5e-71 243.28 In-house 1-296 (296) Show / Hide 
Range on Protein: 2939-3209
Range on HMM: 1-296/296
Sequence Identity: 27% (83 aa)

IEIQRTLGSGQFGVVFQAQVRKNG---QLLTAAVKKAVVGETEEVSRQLNI---DLLAEAY-LLMLAKPH--DHVVGLLGFHLAGSSVLVALDFAKGGDL
... |.||.|.||.|. | ...     ...  |||...   ......|      |.. ||  | |....|   .|..|.| .....  .... ....|||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ---HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDL

ESYLASLAA----RDAQVRFES-TVMVWYALIPXQIASGLAHLHAVGIVHRDVATRNVLLKSSK-----PLHLVLTDLG---LARAIN---------ESI
 ||| . .     ...... .. . |.|      .||.|...||  |.||||.| ||.|. ..       .  .. |.|   ..|..|         || 
RSYLRRHRPTPPACPHWLTLHQRLCMAW------DIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESY

YYKQTSKTAVPFPWMSPESLINR-RSSPASDVWSLGVTAWEICSNGARPWGGMEPQDIVLAVHRG--QRLAISNNWPEQIQSLLRSSWELDTNLRPSARD
||.... ...|. ||.||.|... | . .|||||.||. |||...|..|..||  ......|..|  .|..     |...  |... |. |   ||...|
YYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFED

YVSKL
 |...
LVQQM
Kinase RTKK2.AA Pkinase_Tyr 2939-3209 26 6.3e-65 220.52 Pfam 1-270 (270) Show / Hide 
Range on Protein: 2939-3209
Range on HMM: 1-270/270
Sequence Identity: 26% (75 aa)

IEIQRTLGSGQFGVVFQAQVR--KNGQLLTAAVKKAVVGETEEVSRQL--NIDLLAEAYLLMLAKPHDHVVGLLGFHL-AGSS--VLVALDFAKGGDLES
|.. ..||.|.||.|...  .  . .. .. |||.      |  . .     |...|| ...    |...| |.|  .  | .  ... . ....||| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

YLASLAARDAQVRFESTVMVWYALIPXQIASGLAHLHAVGIVHRDVATRNVLLKSSKPLHLVLTDLGLARAI-NESIYYKQTSKTAVPFPWMSPESLINR
|| .    . . ..    .. ...   |||.|...|.. ...|||.|.||.|...  ...   .| ||||.| |.. ||...... .| .||.||.. ..
YLRKHR--EDKQPLTMKDLLQMCW---QIAKGMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYG

RSSPASDVWSLGVTAWEICSNGARP-WGGMEPQDIVLAV-HRGQRLAISNNWPEQIQSLLRSSWELDTNLRPSARDYVSKL
. . .||||| ||. |||.. |. | . || ..... ..  .|.|...  | |. | .|... |. | . ||. .. ...|
KFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase RTKK2.AA TyrKc 2939-3209 24 1.2e-60 208.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 2939-3209
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)

IEIQRTLGSGQFGVVFQAQVRKNGQLLTAAVKKAVVGETEEVSRQLNIDLLAEAYLLMLA-KPHDHVVGLLGFHLAG-------SSVLVALDFAKGGDLE
|.  ..||.|.||.|.... .     .. |||.   .           |.. || ...   . |...| |.|  . .         ... . ....||| 
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

SYLASLAARDAQVRFESTVMVWYALIPXQIASGLAHLHAVGIVHRDVATRNVLLKSSKPLHLVLTDLGLARAINES-------IYYKQ----TSKTAVPF
.|| .   .     .    .. ...   |||.| ..||  ...||| |.||.|... .  .   .| ||.|.| .         ||..     .|| .| 
DYLRKHRPK-----LCMKDLLSFCW---QIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI

PWMSPESLINRRSSPASDVWSLGVTAWEICSNGARPWGG-----MEPQDIVLAVHRGQRLAISNN--------WPEQIQSLLRSSWELDTNLRPSARDYV
 ||.||..  .. ...||||| ||. |||...|. |. |     |..|...  | .| |. .  |         |. . .. .. |. | . ||. .. .
RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIH

SKL
...
ECF
Kinase RTKK2.AA TK-Unique 2939-3209 25 8.5e-50 169.88 In-house 1-294 (294) Show / Hide 
Range on Protein: 2939-3209
Range on HMM: 1-294/294
Sequence Identity: 25% (75 aa)

IEIQRTLGSGQFGVVFQAQVRKNGQLLTAAVKKAVVGETEEVSRQLNIDLLAEAYLLMLAKPHDHVVGLLGFHLAGS-SVLVALDFAKGGDLESYLASLA
.|.....|.|.|| |. ..|...     . .. ||.   .... .   |.| |. ...  ..| ..| .||     . ... .. .. .|.|..|| . .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

----------------ARDAQVRFESTVMVWYAL-IPXQIASGLAHLHA--VGIVHRDVATRNVLLKSSKPLHLVLTDLGLAR-AINESIYYKQTSKTAV
                ...    ......    . .  |||.|...|.    .|||||...||||| .   . . ..|.|.||   ..  | ...|.  .
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE--DKVCKICDFGMARDVYTNGVYSMMCSQGRI

PFPWMSPESLI--NRRS-SPASDVWSLGVTAWEICSNGARPWGGMEPQDIVLAVHRGQRLAISNNW-PEQIQSLLRSSWELDTNLRPSARDYVSKL
|  ||.||||    .   .. |||||.||. |||...||.| .|| . ||. .. .| |.   ..  .... .|..| | ..   ||| |. ...|
PIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase RTKK2.AA RTKA 3059-3174 47 2.8e-38 131.74 In-house 151-267 (314) Show / Hide 
Range on Protein: 3059-3174
Range on HMM: 151-267/314
Sequence Identity: 47% (56 aa)

QIASGLAHLHAVGIVHRDVATRNVLLKSSKP-LHLVLTDLGLARAINESIYYKQTSKTAVPFPWMSPESLINRRSSPASDVWSLGVTAWEICSNGARPWG
|.|...|.|   |||||||| ||||  |  | .|  | |.|| |    | ||| ... . || || || .  || | .|||||.|| .||. . |. ||.
QVAQAMAYLAKCGIVHRDVAARNVLVMSLQPAFHCKLADFGLSRVMPSSDYYKSRADDEMPFRWMAPECIMERRYSEHSDVWSFGVLVWELLTHGQTPWQ

GMEPQDIVLAVHRGQRL
  |   ||  . || ||
NCESHQIVALLMRGERL
Kinase RTKK2.AA TKL 2945-3209 17 4.9e-37 129.37 In-house 1-364 (364) Show / Hide 
Range on Protein: 2945-3209
Range on HMM: 1-364/364
Sequence Identity: 17% (67 aa)

LGSGQFGVVFQAQVRKNG------QLLTAAVKKAVVGETEEVSRQLN--------------------IDLLAEAYLLMLAKP-HDHVVGLLGFHLAGSS-
.||| ||.|.... | .|         . ||||  . .  | .....                    .    |  ..|. .  |...| ..|. ..... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VLVALDFAKGGDLESYLASLAARDAQVRFESTVMVWYALIPXQIASGLAHLHA--------VGIVHRDVATRNVLLKSS---------
                 ....||.|..||                .     .  .||.|...||.         .|.|||  ..|.|...          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMY

---KPLHLVLTDLGLARAINESI----------------YYKQTSKTAV-PFPWMSPESLINR----------------RSSPASDVWSLGVTAWEICSN
   .. .. ..|.||.| ...|                  ...|. | .  . ||.|| | .                   |...||.| |.  |||.. 
NPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTR

GARPW--GGMEPQD--------IVLAVHRGQRLAIS------------NNWPEQIQSLLRSSWELDTNLRPSARDYVSKL
   |.   ...|..        .......|.|. |             .. |... .|.   |. | . |||. . ...|
CR-PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase RTKK2.AA Fer 3059-3210 29 6.3e-37 123.35 In-house 119-283 (283) Show / Hide 
Range on Protein: 3059-3210
Range on HMM: 119-283/283
Sequence Identity: 29% (49 aa)

QIASGLAHLHAVGIVHRDVATRNVLLKSSKPLHLV---LTDLGLARA--INESIYYKQTSKTAVPFPWMSPESLINRRSSPASDVWSLGVTAWEICSNGA
|.|.|...||. ...|||.| ||.|.  .|  . .   ..| |..|.   ... |..    . ||  |..||.. ..  ||..|||| ||..|||..|||
QAACGMEYLHSKNCIHRDIAARNCLY--HKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGA

RPWGG----MEPQDI----VLA-VHRGQRLAISNNWPEQIQSLLR-SSWELDTNLRPSARDYVSKLP
 |..|    | .  .    . . .. | .. . |. |. | ...  . |. |.. ||.. . . || 
EPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase RTKK2.AA S_TKc 2939-3212 20 3.1e-34 120.99 SMART 1-231 (231) Show / Hide 
Range on Protein: 2939-3212
Range on HMM: 1-231/231
Sequence Identity: 20% (59 aa)

IEIQRTLGSGQFGVVFQAQVRKNGQLLTAAVKKAVVGETEEVSRQLNIDLLAEAYLLMLAKPHDHVVGLLGFHLAGSSVLVALDFAKG--GDLESYLASL
 || |..|.| ||.|.... .| |..   |.|.              .... |  .|.    |...| |...    ... . .... |  ||| .|. . 
YEILRKIGKGAFGKVYKCRHKKTGRIV--AIKIIK------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR

AARDAQVRFESTVMVWYALIPXQIASGLAHLHAVGIVHRDVATRNVLLKSSKPLHLVLTDLGLARAINESIYYKQTSKTAVPFPWMSPESLINRRSSP-A
  .  ...|   .   |.    ||...|...|  ||.|||.   |.|| .    |. ..| |||| .         .   .   .|.|| |     .. .
GRHGLRFPFPE-HARFYMY---QICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCK

SDVWSLGVTAWEICSNGARPWGGMEPQDIVLAVHRGQRLAISNNWPEQIQSLLRSSWELDTNLRPSARDYVS------KLPAV
.|.||.|.. .| .. |  |.      .. .  ..          ...  ...|  .. | . ||.| .         . | .
CDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RTKK2.AA FAK 3059-3214 36 8.8e-34 110.46 In-house 132-285 (285) Show / Hide 
Range on Protein: 3059-3214
Range on HMM: 132-285/285
Sequence Identity: 36% (57 aa)

QIASGLAHLHAVGIVHRDVATRNVLLKSSKPLHLVLTDLGLARAINESIYYKQTSKTAVPFPWMSPESLINRRSSPASDVWSLGVTAWEICSNGARPWGG
|..  .| |     ||||.| ||||  |  |    | | || | .. . ||| . |.. |  ||||||   ||   |||||  ||  ||| . | .|  .
QLCMAMAYLESKKFVHRDIAARNVLVSS--PDCVKLGDFGLSRWMHDHSYYKASPKGKLPIKWMSPESINFRRFTTASDVWMFGVCMWEILMYGVKPFQW

MEPQDIVLAVHRGQRLAISNNWPEQIQSLLRSSWELDTNLRPSARDYVSKLPAVGR
.. .|... . .| ||   .| |    ||.   |. |   ||  .. . .|  .  
VKNNDVIGRIENGERLPMPPNCPPTLYSLMTRCWAYDPSKRPRFKELKCQLKDIYQ
Kinase RTKK2.AA FGTK 3059-3209 34 5e-32 108.55 In-house 110-302 (302) Show / Hide 
Range on Protein: 3059-3209
Range on HMM: 110-302/302
Sequence Identity: 34% (67 aa)

QIASGLAHLHAVGIVHRDVATRNVLL-KSS-KPLHLV-LTDLGLARAI-NESIYYKQTSKTAVPFPWMSPESLINRRSSPASDVWSLGVTAWEICSNGAR
.|.|||.|.|. . |||| | |||||  ..     .. | | || | . ..  ||. .. .. || ||.||.|  .| ||||||||||||.||| . |. 
HITSGLCHVHDCQLVHRDMACRNVLLFSRPHMACPQAKLADFGLSRYVSDDHDYYRASQLDDMPFRWMAPEALRHGRFSPASDVWSLGVTIWEIFNQGQT

PWGGMEPQDIVLAVHRGQRLAISNNWPEQIQS---------------------------------------LLRSSWELDTNLRPSARDYVSKL
| |.   | |.     ||||  | . |.   .                                       ||.. |..   .|||||  |  |
PYGERTMQMILEFLQSGQRLDLS-HIPPALHHLYMTRNCLYFPFAMLGTAPWDPHVLLPTSCCCWCVLHPRLLTQMWHANPERRPSAREVVHAL
Kinase RTKK2.AA RTKB 3059-3209 34 8.6e-32 104.46 In-house 117-264 (264) Show / Hide 
Range on Protein: 3059-3209
Range on HMM: 117-264/264
Sequence Identity: 34% (52 aa)

QIASGLAHLHAVGIVHRDVATRNVLLKSSKPLHLVLTDLGLARAINESIYYKQTSKTAVPFPWMSPESLINRRSSPAS-DVWSLGVTAWEICSNGARPWG
|||.| |.||  ...||| . ||||.  .. ||    | |.||.| .  | . . ....   || |||.  |. .  | ||||.|||.||| | |. |. 
QIACGMAFLHQHNVIHRDLCARNVLV--DQQLHCKICDFGMAREIDHECYETTCTRLPI--KWMAPESWAHRIYTTKSGDVWSFGVTMWEIFSLGGTPYQ

GMEPQDIVLAVHRGQRLAISNNWPEQIQSLLRSSWELDTNLRPSARDYVSKL
  .  ||      | ||      | ..  ...  | ..   ||.    |. .
QYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase RTKK2.AA Pkinase 2939-3209 18 1.1e-28 102.57 Pfam 1-293 (293) Show / Hide 
Range on Protein: 2939-3209
Range on HMM: 1-293/293
Sequence Identity: 18% (59 aa)

IEIQRTLGSGQFGVVFQAQVRKNGQLLTAAVKKAVVGETEEVSRQLNIDLLAEAYLLMLAKPHDHVVGLLGFHLAGSSVLVALDFAKGG----DLESYLA
..| |..||| ||.|.... ...|.  . |||.  . ....  .| .. | .|....     |...| |...   .... . .... ||    || .|. 
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

SLAARDAQVRF--ESTVMVWYALIPXQIASGLAHLHAVGIVHRDVATRNVLLKSSKPLHL----VLTDLGLARAINESIYYKQTSKTAVP--FPWMSPES
     ... .|  .  .   |..   ||..||...|. ||.|||.   |.|..  .  |.     ..| |||. ..   | ...  | .    ..|.|| 
T----WRHGCFYFSEWECKFYMY---QILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEV

LI-NRRSSPASDVWSLGVTAWEICSNGARPWGG----MEPQDIVLAVHRGQRLAISNNW----------------------PEQIQSLLRSSWELDTNLR
.  ..  .|..|.||.|.. .| ..     .|         .... . ....   .. .                      .|  ...... ...| . |
IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKR

PSARDYVSK--L
|.|.. .    .
PTAEQILQHPWF
Kinase RTKK2.AA Fer 2939-3033 24 1.4e-09 28.86 In-house 1-100 (283) Show / Hide 
Range on Protein: 2939-3033
Range on HMM: 1-100/283
Sequence Identity: 24% (25 aa)

IEIQRTLGSGQFGVVFQAQ---VRKNGQLLTA---AVKKAVVGETEEVSRQLNIDLLAEAYLLMLAKPHDHVVGLLGFHLAGSSVLVALDFAKGGDLESY
....  ||.| || |....    .|.|  ..    ||| . . . | ...   .....||....    |..|| . |.      ... . |..||.|.||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKC-EDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSY

L
|
L
Kinase RTKK2.AA RTKB 2939-2963 44 2e-06 17.48 In-house 1-25 (264) Show / Hide 
Range on Protein: 2939-2963
Range on HMM: 1-25/264
Sequence Identity: 44% (11 aa)

IEIQRTLGSGQFGVVFQAQVRKNGQ
. . . ||.| || ||||.||  ..
VWLGEKLGNGAFGEVFQAWVRNRHM
Kinase RTKK2.AA FGTK 2939-2958 40 0.000216 11.25 In-house 1-20 (302) Show / Hide 
Range on Protein: 2939-2958
Range on HMM: 1-20/302
Sequence Identity: 40% (8 aa)

IEIQRTLGSGQFGVVFQAQV
  .|. || | ||.|..| .
LQDQPPLGKGNFGTVYKAIP
Kinase RTKK2.AA RTKA 2939-2971 23 0.000374 10.64 In-house 1-38 (314) Show / Hide 
Range on Protein: 2939-2971
Range on HMM: 1-38/314
Sequence Identity: 23% (9 aa)

IEIQRTLGSGQFGVVFQAQVRKNG----QL-LTAAVKK
..... .|.| |..| ||. .  .    |.  ..|.|.
MQVRHVVGHGHFSQVYQASLQDMEDEMRQGPQCVAIKE
Kinase RTKK2.AA FAK 2939-2955 52 0.001267 7.83 In-house 1-17 (285) Show / Hide 
Range on Protein: 2939-2955
Range on HMM: 1-17/285
Sequence Identity: 52% (9 aa)

IEIQRTLGSGQFGVVFQ
|.  | .| |||| |.|
ITLNRCIGEGQFGDVYQ