Gene Src2 (M.brevicollis)

Src2

Species: M.brevicollis
Alias: Src2
External Links:
Annotation:

Classification

Group: TK
Family: SFK-Src

Sequence

Name Sequence Type Origin Length Description Download
Src2.AA Protein None 507 None Fasta, JSON
Src2.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of Src2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 Src2.AA SH3 60-117 43 9.2e-25 89.5 SMART 1-58 (58) Show / Hide 
Range on Protein: 60-117
Range on HMM: 1-58/58
Sequence Identity: 43% (25 aa)

NVVVALYHYESRTDDDLSFRKGDEMAVTDDGDGDWWQARHLTTGQVGYIPSNFVAKVQ
 .|.||| |.....|.|||.||| . |... |..||..|. .|||.|..|||.|....
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 Src2.AA SH3_1 63-110 48 8.6e-21 73.01 Pfam 1-49 (49) Show / Hide 
Range on Protein: 63-110
Range on HMM: 1-49/49
Sequence Identity: 48% (24 aa)

VALYHYESRTDDDLSFRKGDEMAVTDDGDG-DWWQARHLTTGQVGYIPS
|||| |. ...|.|||.|||.. | .. |. ||| .| ..|||.|..||
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 Src2.AA SH3_2 61-116 22 3.9e-12 45.37 Pfam 1-68 (68) Show / Hide 
Range on Protein: 61-116
Range on HMM: 1-68/68
Sequence Identity: 22% (15 aa)

VVVALYHYES-RTDDD-----LSFRKGDEMAVT---DDGDGDWWQA-RHLTTGQV--GYIPSNFVAKV
..... .|.. .  ..     |.|.|||  .|.   |  ...||.. . ...|..  |..||..|...
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 Src2.AA SH2 124-200 50 5.6e-46 136.81 Pfam 1-81 (81) Show / Hide 
Range on Protein: 124-200
Range on HMM: 1-81/81
Sequence Identity: 50% (41 aa)

WFHGQIKRAEADKALMT-IGSHGSFLIRSSESQPGEYSLSLRSGD---NIKHYRIRKLDAGGFYIVTRLPFNSLPELVQHY
|.|| | |.|| . ||   . .|.||.| |||.||.|.||.| ..   ..|||||...| ||.|| .|  |.||.|||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 Src2.AA SH2 122-206 46 1.1e-35 125.79 SMART 1-87 (87) Show / Hide 
Range on Protein: 122-206
Range on HMM: 1-87/87
Sequence Identity: 46% (41 aa)

NDWFHGQIKRAEADKALMTI-GSHGSFLIRSSESQPGEYSLSLRSGDNIKHYRIRKLDAGGFYIVT--RLPFNSLPELVQHYGQDADG
  |.|| | |.||.. |..  . .|.||.| |||.||.|.||.|... .||||||..| |..|| .  | .|.|| |||.|| . ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase Src2.AA SFK-Src 241-495 76 5.1e-248 744.16 In-house 1-259 (259) Show / Hide 
Range on Protein: 241-495
Range on HMM: 1-259/259
Sequence Identity: 76% (199 aa)

IALQQRLGSGQFGDVWQGTWNNKTAVAVKTLKPGTMSEKEFLAEAAVMKRLRHPKLIQLYAVCTDGEPIYIVTELMANGSLLDYLQE-NGHSLRMPLLVD
|.|...||||||||||.|.|||.|.|||||||||.||..|||.||.|||.||||.||||||||||||||||.||||..|||||||.| .|.|||||.|||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

MGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSNVVKVGDFGLSRILAADSE-YTAREGAKFPIKWTAPEAATMSKFSIKSDVWSFGILLYELVTYGRIPY
|.||||.|||||||||||||||||||||||..||.||||||.||.||.|.| |||.||||||||||||||..|..|||||||||||||..|.||||||||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMTNMEVLQQLER--GYRMPCPPGTPDALYVIMRECWIEEPSERPTFENLLWRMEEFF
|||||||||||..|  ||||||||..||..|.||..||..||..|||||.|.|.||.||
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase Src2.AA Src 241-491 67 1.2e-182 613.05 In-house 1-255 (255) Show / Hide 
Range on Protein: 241-491
Range on HMM: 1-255/255
Sequence Identity: 67% (171 aa)

IALQQRLGSGQFGDVWQGTWNNKTAVAVKTLKPGTMSEKEFLAEAAVMKRLRHPKLIQLYAVCTDGEPIYIVTELMANGSLLDYLQ--ENGHSLRMPLLV
| | ..||.||||.||.|.||..| |||||||||||| . ||.|| .|| |||.||.||||||...||||||||.|..|||||||.  . |..|..| |.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DMGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSNVVKVGDFGLSRILA-ADSEYTAREGAKFPIKWTAPEAATMSKFSIKSDVWSFGILLYELVTYGRIP
||.||||.||||||..|..||||||||||||..||.||.|||| |..   | ||.||.|||||||||||||..  .|.||||||||||||.|.|||||.|
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YPGMTNMEVLQQLERGYRMPCPPGTPDALYV-IMRECWIEEPSERPTFENLLWRM
||||||.|||||.|||||||||.. || ||  ||..|| ..| .||||| | | .
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Src2.AA Frk 241-495 66 3.3e-159 535.2 In-house 1-260 (260) Show / Hide 
Range on Protein: 241-495
Range on HMM: 1-260/260
Sequence Identity: 66% (174 aa)

IALQQRLGSGQFGDVWQGTWNNKTAVAVKTLKPGTMSEKEFLAEAAVMKRLRHPKLIQLYAVCTDGEPIYIVTELMANGSLLDYLQ---ENGHSLRMPLL
| | .||||||||.|| | |||.| |||||||||||  ..||.|| .||.||||||||||||||  |||||.|||| .|||..|||   ..|....|. |
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDMGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSNVVKVGDFGLSRILAADSE--YTAREGAKFPIKWTAPEAATMSKFSIKSDVWSFGILLYELVTYGR
||| ||||||||||| ||..||||||||||||..|..|. |||| |.|  | |  | .| ||.||||||||||| ..||.||||||||||||.|..||||
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

IPYPGMTNMEVLQQLERGYRMPCPPGTPDALYVIMRECWIEEPSERPTFENLLWRMEEFF
.||||||| ||||....|||||.||. |  || || ||| ..| .||||| | |..|..|
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase Src2.AA Pkinase_Tyr 241-491 49 1.9e-154 523.71 Pfam 1-270 (270) Show / Hide 
Range on Protein: 241-491
Range on HMM: 1-270/270
Sequence Identity: 49% (133 aa)

IALQQRLGSGQFGDVWQGTWN-----NKTAVAVKTLKPGTMSE----KEFLAEAAVMKRL-RHPKLIQLYAVCT-DGEP--IYIVTELMANGSLLDYLQE
| . . ||.|.||.|..|||.     .|. ||||.||.|.|.|    ..|..||..|| | .||....||.||| .|||  ||||.|.|..|.|||||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N---GHSLRMPLLVDMGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSNVVKVGDFGLSRILAADSEY-TAREGAKFPIKWTAPEAATMSKFSIKSDVWSF
.   ...| |. |..| .|.|.||.|||..|..||||||||.||. .||||..||||.| .  |..| ..|.|.|.||||.|||.   .||..|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLYELVTYGRIP-YPGMTNMEVLQQL-ERGYRMPCPPGTPDALYVIMRECWIEEPSERPTFENLLWRM
|.|..|..|||..| ||||.| ||.... |.|||||||...|| .| .|..|| ..|..||||. .....
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Src2.AA SrcA 241-491 63 4.8e-150 477.62 In-house 1-250 (250) Show / Hide 
Range on Protein: 241-491
Range on HMM: 1-250/250
Sequence Identity: 63% (160 aa)

IALQQRLGSGQFGDVWQGTWNNKTAVAVKTLKPGTMSEKEFLAEAAVMKRLRHPKLIQLYAVCTDGEPIYIVTELMANGSLLDYLQE-NGHSLRMPLLVD
|.|..||| |.||.|| |||| .| ||.||||||||| . || || .||.||| ||.|||||  . |||||||| |. |||||.|.. .|. |..| |||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSE-EPIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

MGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSNVVKVGDFGLSRILAADSEYTAREGAKFPIKWTAPEAATMSKFSIKSDVWSFGILLYELVTYGRIPYP
| ||||.||||.|  |..|||| | |.|||.  . |. |||| | |  | ||||| ||||||||||||||   .| |||||||||||| |||| ||.|||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLAR-LIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP

GMTNMEVLQQLERGYRMPCPPGTPDALYVIMRECWIEEPSERPTFENLLWRM
|| | |||.| ||||.||||.. | .|. .| .||  .| |||||| |   .
GMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase Src2.AA Src-Unclassified 241-487 51 2.7e-149 502.26 In-house 1-280 (284) Show / Hide 
Range on Protein: 241-487
Range on HMM: 1-280/284
Sequence Identity: 51% (144 aa)

IALQQRLGSGQFGDVWQGTWNNKTAVAVKTLKPG---TMSEKEFL--------AEAAVMKRLRHPKLIQLYAVCTDGEPIYIVTELMANGSLLDYLQENG
. |   || |||| || | | .|  |||||..||   |||   ||        .||..|| .||..|..|||||.. ||.||.||.| |||||..|.| |
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

-HSLRMPLL------------VDMGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSN-----VVKVGDFGLSR-ILAADSEYTAREGAKFPIKWTAPEAAT
   | ....            ||. |||| || |||.   |||||||||||.|  |     |||| |||| |  | .| .| .| ||.||.||.|||...
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

MSKFSIKSDVWSFGILLYELVTYGRIPYPGMTNMEVLQQLERGYRMPCP--PGTPDALYV-IMRECWIEEPSERPTFENL
  .|||||||||.||||.|. |.|..||||| | ||| ..||||||| |   . || .|  ||  || . |  ||||. |
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTL
Kinase Src2.AA TyrKc 241-491 42 1.2e-140 474.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 241-491
Range on HMM: 1-280/280
Sequence Identity: 42% (122 aa)

IALQQRLGSGQFGDVWQGTWNNKTAVAVKTLKPGTMSEKEFLAEAAVMKRL--RHPKLIQLYAVCTDG-------EPIYIVTELMANGSLLDYLQENGHS
| | . ||.|.|| |..|||.  . ||||.||...  ...|. || .|..|  .|| ...||.|||..       ||..||.|.|..|.|.|||..... 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LRMPLLVDMGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSNVVKVGDFGLSRILAAD-------SEYTARE--GAK--FPIKWTAPEAATMSKFSIKSDV
| |. |...  |.|.||.||. .|..||||||||.|||  ..||..|||||| .  |       . |...|  |.|  .||.|.|||.   .||..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGILLYELVTYGRIPYPG-----MTNMEVLQQLERGYRMPCPPG--------TPDALYVIMRECWIEEPSERPTFENLLWRM
||||....|. |||  ||||     |.| ||......|||||.||          ||..| ||..|| |.|..||||...  ..
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Src2.AA SrcB 241-492 61 2.3e-134 452.69 In-house 1-251 (251) Show / Hide 
Range on Protein: 241-492
Range on HMM: 1-251/251
Sequence Identity: 61% (155 aa)

IALQQRLGSGQFGDVWQGTWNNKTAVAVKTLKPGTMSEKEFLAEAAVMKRLRHPKLIQLYAVCTDGEPIYIVTELMANGSLLDYLQ-ENGHSLRMPLLVD
. | ..||.||||.|| |..||.. |||||.|.|||| . ||||| ||| | | .|..|||| |  |||||.|| ||.|.|||.|. ..|  | .| |.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTK-EPIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

MGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSNVVKVGDFGLSRILAADSEYTAREGAKFPIKWTAPEAATMSKFSIKSDVWSFGILLYELVTYGRIPYP
| ||.| ||||.| .|..|||| | |.|| .. . |. |||| ||.  | |||||||||||||||||||     | ||||||||||||.|.|||||||||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARII-EDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

GMTNMEVLQQLERGYRMPCPPGTPDALYVIMRECWIEEPSERPTFENLLWRME
|||| ||...||||||||.|   |. || ||..|| | | |||||. |   ..
GMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase Src2.AA TK 241-491 26 1.8e-130 439.72 In-house 1-486 (486) Show / Hide 
Range on Protein: 241-491
Range on HMM: 1-486/486
Sequence Identity: 26% (129 aa)

IALQQRLGSGQFG---DVWQGTWNNK--------------------------TAVAVKTLKPG-TMSEKEFLA--------------EAAVMKRLR----
| | . ||.||||   .|..|.|...                          | ||||.||.| .||..||..              ||..|| ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPKLIQLYAVCTDG------------EPIYIVTELMANGS----LLDYLQENGHS--------------------------------------------
 || ...||.|||.|            ||..||.|.|..|.    |.|||... .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LRMPLLVDMGAQVAAGMAYLEAQ------NFVHRDLAARNVLVGQSNV-----------VKVGDFG---
                               | |. |. | .|.|.||.||...      |||||||||||.|||..||           .|..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRILAADSEYTARE------------------------GAKFPIKWTAPEAAT---------MSKFSIKSDVWSFGILLYELVTYGRIPYPG-M
     |.| .  |..|....                        |.|.||.|.|||. .           ||..||||||||.|..|..|||. ||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TN---------MEVLQQLERG--------------YRMPCPPGTP--------------DALYVIMRECWIEEPSERPTFENLLWRM
.|          ||...|.||              .|||.||. |              ...| .|..|| ..|..||||. |. ..
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Src2.AA Src-Echino1 241-491 57 2.1e-128 432.87 In-house 1-252 (252) Show / Hide 
Range on Protein: 241-491
Range on HMM: 1-252/252
Sequence Identity: 57% (146 aa)

IALQQRLGSGQFGDVWQGTWNNKTAVAVKTLKPGTMSEKEFLAEAAVMKRLRHPKLIQLYAVCTDGEPIYIVTELMANGSLLDYL-QENGHSLRMPLLVD
  .....|.|..|.||.| ||  | |||||||..|||. .||||| |||..||  ..|.|||| | |||||||||| ||.|.||| ..... ..|. |.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

MGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSNVVKVGDFGLSRILAADSEYTAREGAKFPIKWTAPEAATMSKFSIKSDVWSFGILLYELVTYGRIPYP
|||..|.|| ||. .|.|||||||||||||. ||.|. |||| |..  | .| ...|||.||||||||||   .| |||||||||||. |.||.||.|||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKD-VYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYP

GMTNMEVLQQLERGYRMPCPPGTPDALYVI-MRECWIEEPSERPTFENLLWRM
||.|.|||.|..|||||| .   ||.|| . |  ||  .|  ||||| |   .
GMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase Src2.AA Tec 241-493 48 7.2e-122 411.17 In-house 1-254 (254) Show / Hide 
Range on Protein: 241-493
Range on HMM: 1-254/254
Sequence Identity: 48% (124 aa)

IALQQRLGSGQFGDVWQGTWNNKTAVAVKTLKPGTMSEKEFLAEAAVMKRLRHPKLIQLYAVCTDGEPIYIVTELMANGSLLDYLQENGHSLRMPL--LV
... . ||||||| |  | | ..  ||.|..| |.||| .|. || ||. | ||||.||| ||.   ||||||| |..|.||.|| |..| ..  .  | 
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

DMGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSNVVKVGDFGLSRILAADSEYTAREGAKFPIKWTAPEAATMSKFSIKSDVWSFGILLYELVTYGRIPY
.|  .|  |||||| ..|.|||||||| |||. .|||| |||..|    | .||   |.|||.|| .||    |..| |||||.||.|  |  . |..||
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDD-QYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPY

PGMTNMEVLQQLERGYRMPCPPGTPDALYVIMRECWIEEPSERPTFENLLWRMEE
. |.|.|| ..  .|.|.  |   .. .| || .|| |.| |||||..||  ..|
ENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase Src2.AA SRM 242-492 50 4.5e-120 403.41 In-house 2-253 (253) Show / Hide 
Range on Protein: 242-492
Range on HMM: 2-253/253
Sequence Identity: 50% (128 aa)

ALQQRLGSGQFGDVWQGTWNNKTAVAVKTLKPGT-MSEKEFLAEAAVMKRLRHPKLIQLYAVCTDGEPIYIVTELMANGSLLDYLQE-NGHSLRMPLLVD
.| ..||.| || || | |  .  ||.|  |    |  ... .|   || ||| ..| |.|||. |.|.||.||||. |.|. || . ..  |..| |.|
TLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLLD

MGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSNVVKVGDFGLSRILAADSEYTAREGAKFPIKWTAPEAATMSKFSIKSDVWSFGILLYELVTYGRIPYP
.  ||| ||.||| ||..||||||||||||  |. ||||||| | .  |  |    . . |.||||||||    .|.|||||||||||.|. ||| .|||
FACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDI-YSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYP

GMTNMEVLQQLERGYRMPCPPGTPDALYVIMRECWIEEPSERPTFENLLWRME
|||| | .|| .||||||||   |   .. | |||  .| .||.|  |  .. 
GMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase Src2.AA S_TKc 241-495 23 5.2e-59 203.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 241-495
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

IALQQRLGSGQFGDVWQGTWNN-KTAVAVKTLKPGTMSEKEFLAEAAVMKRLRHPKLIQLYAVCTDGEPIYIVTELMAN--GSLLDYLQENGHS-----L
  . . .|.| || |....... .  ||.| .|      . .. | ...|. .|| ...|| |. | . .|.|.|.. .  |.|.||....|.      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

RMPLLVDMGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSNVVKVGDFGLSRILAADSEYTAREGAKFPIKWTAPEAATMSKFSI-KSDVWSFGILLYELV
       . .|.. ...|.  ....||||   |.|. .  ..|..||||.|.|                 . |||     ...  |.|.||.|..|||..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TYGRIPYPGMTNMEVLQQLERGYRMPCPPGTPDALYVIMRECWIEEPSERPTFENLLW-----RMEEFF
. |. |.|  . .......           .|.|.  ..| |.  .|..|||   .|      .. ..|
C-GYPPFP--QMQMMFKKIG----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Src2.AA Pkinase 241-491 24 1.8e-46 165.39 Pfam 1-293 (293) Show / Hide 
Range on Protein: 241-491
Range on HMM: 1-293/293
Sequence Identity: 24% (72 aa)

IALQQRLGSGQFGDVWQGTWNNKTA-VAVKTLKPGTMSEKEF-----LAEAAVMKRLRHPKLIQLYAVCTDGEPIYIVTELMANG----SLLDYLQ-ENG
. . ...||| || |..... .    ||||..|  . ....      |.|...||||.||  ..|| ...|.  ||.|.|.. .|    .| ||.. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

HSL--RMPLLVDMGAQVAAGMAYLEAQNFVHRDLAARNVLVGQSNVV----KVGDFGLSRI--LAADSEYTAREGAKFPIKWTAPEAAT-MSKFSIKSDV
 ..   .  . ..  |.. |..|. .....||||   |.|. . ...    |..||||..   .  .| .| . |  .   . |||     .. . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW---YMAPEVIRGGQYYGPKVDM

WSFGILLYELVTYGRIPYPGM------TNMEVLQQLER-GYRMPCPPGTP-------------------DALYVIMRECWIEEPSERPTFENLLWR--M
||.|..|||... || |.||       . |.....  .  .. ..|   .                   ...  ... |.   |..|||.| .|    .
WSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF