36983

Species: M.brevicollis
Alias: 36983
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Cbl

Sequence

Name Sequence Type Origin Length Description Download
36983.AA Protein None 554 None Fasta, JSON

Protein domain

Protein domains of 36983.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Cbl_N 36983.AA Cbl_N 36-155 36 1.1e-33 118.82 Pfam 1-122 (130) Show / Hide
Range on Protein: 36-155
Range on HMM: 1-122/130
Sequence Identity: 36% (45 aa)

WQNTIDTKTLLRIDKNTERLITLCQNPRLNLKNSPPFLQGILFDTREHLHALFERNPL--EALRQNAFVSIFLIKFLSHCKRASNLFKEAGDRMEDEQSE
   . | |.|..  |   . . ||..|..||||||||   || ||  ||   . .|    . | .| .  .|.   .  || .  ||||  .|| .|.|.
FCSEEDKKMLEKCWKFMDKVVKLCHQPKMNLKNSPPFILDILPDTYQHLMLIYSQNEDQMHILHDNEYFKVFMENMMRKCKQIIKLFKEGKERMYNENSH

DRRELNRLTLVFSHMLADFKSL
 || | .. |.|||||.  | .
YRRNLTKMSLIFSHMLFELKAI

Cbl_N2 36983.AA Cbl_N2 164-247 55 2.9e-40 128.13 Pfam 1-86 (86) Show / Hide
Range on Protein: 164-247
Range on HMM: 1-86/86
Sequence Identity: 55% (48 aa)

DFLIVKIGAREFWNAAFPHRSIVPWGEFLHQLKKVH--EIGEPEEAALKKTMDITENDHISAFEFDVFTRLFQPWKQLINNWSLIA
 | . |  | |||   .  | |||| ||   |.|.|  |.| .| .||| |.| | ||||| |||||||||||||. |. || | |
MFRMTKADAHEFWRHHCGKRCIVPWKEFRQCLCKCHPIEPGKMEAMALKTTIDLTCNDHISNFEFDVFTRLFQPWPTLLRNWQLLA

Cbl_N3 36983.AA Cbl_N3 249-334 65 2.2e-46 165.18 Pfam 1-86 (86) Show / Hide
Range on Protein: 249-334
Range on HMM: 1-86/86
Sequence Identity: 65% (56 aa)

RHPAYQAFITYDEVEATLSNHRHKPGSYVFRLSCTRLGQWAIGFVAKDGQIVQTIPQSKSLYQALIDGAEQGTFLYPNGEDANPDI
 || | ||.|||||.. |   .||||||.||||||||||||||.|. ||.|.||||| |.| |||.||  .| .|||.| | |||.
THPGYMAFLTYDEVKKRLQKCIHKPGSYIFRLSCTRLGQWAIGYVTADGKIYQTIPQNKPLCQALHDGHKEGFYLYPDGRDQNPDL

Zf-C3HC4 36983.AA zf-C3HC4 366-410 33 3.2e-16 47.93 Pfam 1-48 (48) Show / Hide
Range on Protein: 366-410
Range on HMM: 1-48/48
Sequence Identity: 33% (18 aa)

CKICNSNFKSVR---IDPCGHL-----LCHQCLRKWIDSSNTPTSSATTCPFC
| ||  ..|      | ||||       || |...|...     |  |.||.|
CWICHCEWKDPNNPLIHPCGHRGSLKWFCHSCIKRWWNH-----SGNTQCPIC

RING 36983.AA RING 366-410 26 3.2e-09 37.9 SMART 1-23 (23) Show / Hide
Range on Protein: 366-410
Range on HMM: 1-23/23
Sequence Identity: 26% (12 aa)

CKICNSNFKSVRIDPCGHLLCHQCLRKWIDSSNTPTSSATTCPFC
| || .    ... ||||  |. |.                ||.|
CPICLE----PVVLPCGH-FCY-CI----------------CPIC

UBA 36983.AA UBA 513-549 36 2.8e-08 33.53 Pfam 1-38 (38) Show / Hide
Range on Protein: 513-549
Range on HMM: 1-38/38
Sequence Identity: 36% (14 aa)

PDEVLLLELQNM-GFEREAAAKALRISRNSLEVATDIL
.|| .. .|. | ||..... |||| . |..| |...|
IDEEMVKQLMEMTGFSMMQCKKALRACNNNVERAVEWL

UBA 36983.AA UBA 514-551 34 8.7e-07 29.79 SMART 1-38 (38) Show / Hide
Range on Protein: 514-551
Range on HMM: 1-38/38
Sequence Identity: 34% (13 aa)

DEVLLLELQNMGFEREAAAKALRISRNSLEVATDILLQ
.|  . .| .||| ||.. .||| . . .|.|...|..
YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS