Gene 22411 (M.brevicollis)
22411
Species: M.brevicollis
Alias: 22411
External Links:
Annotation:
Sequence
Protein domains of 22411.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| TIG | 22411.AA | TIG | 32-124 | 28 | 6.8e-15 | 52.77 | Pfam | 1-82 (82) | Show / Hide |
Range on Protein: 32-124 Range on HMM: 1-82/82 Sequence Identity: 28% (27 aa) AYITDITP-RQVGYKGGQHITIRGVGFDREGQEGATTVYVGTDVCETIAYYSSDTQIVCVMPEVTVVESYLAVTVSLWVAGGAMGSTAICETSC ||.|.| . .||..|||.| .| .. |..|.|.. | .| ..|.|||||. |..| . |... | . .|.. . . PTITSISPNTTGPPSGGTTITITGQNF--GNDS-DTKCYFGGTPCTVI--WWSSTQIVCTTPPHT------PGTHNVSV-VNGQWSSNPTTFTY |
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| IPT | 22411.AA | IPT | 31-119 | 25 | 0.000725 | 20.09 | SMART | 1-111 (111) | Show / Hide |
Range on Protein: 31-119 Range on HMM: 1-111/111 Sequence Identity: 25% (28 aa) NAYITDITPRQVGYKGGQ-HITIRGVGFDREGQEGATTVYVG----TDVCETIAY-YS---SDTQIVCVMPEVTV---VESYLAV----TVSLWVAGGAM . ||.| |.. || .|||.| || .|. .| || . |. . |. |.|||||..|. .. . | .|.. .. . DPVITRIHPNCGPCSGGTERITICGKNFDSDIQVRFVRVNVGGRVWEVPCTFQPWDYHGKDSQTQIVCCTPPYHNQSPIPGQVPVRVTQEVQF-CNDNVR GS-------TAI .. | TQLSWPQPFTYV |
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| TIG | 22411.AA | TIG | 134-223 | 26 | 6.2e-05 | 19.07 | Pfam | 1-82 (82) | Show / Hide |
Range on Protein: 134-223 Range on HMM: 1-82/82 Sequence Identity: 26% (25 aa) PTISESQ--LAAPP--GGNVTLIG-YLRGITADEFELRLNGTLLETAYESDDVISTSSWNTGRYDAVVPSMTAGYYNVSFLVNRQDSSWGAGFSA |||. . .|| | ..|..| .. |... . ...|| . . |.. | ...|. |.| .|||. || | ||.. |. PTITSISPNTTGPPSGGTTITITGQNF-GNDS-DTKCYFGGTPCTVIWWSSTQI----------VCTTPPHTPGTHNVSV-VNGQWSSNPTTFTY |
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| TIG | 22411.AA | TIG | 243-304 | 19 | 1.8e-05 | 20.87 | Pfam | 1-60 (82) | Show / Hide |
Range on Protein: 243-304 Range on HMM: 1-60/82 Sequence Identity: 19% (12 aa) PVVSALSA-SAAGTLGGALLTVYGDGFDADACVENNVVSVAGVNCVPVACTNTEITCRLEAVV |.....| . . . || ..|..|..| . .. . . |..|... ..|.|.|.. ... PTITSISPNTTGPPSGGTTITITGQNF--GNDS-DTKCYFGGTPCTVIWWSSTQIVCTTPPHT |
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| IPT | 22411.AA | IPT | 242-338 | 15 | 0.003626 | 13.28 | SMART | 1-111 (111) | Show / Hide |
Range on Protein: 242-338 Range on HMM: 1-111/111 Sequence Identity: 15% (18 aa) HPVVSALSASAAGTLGGA-LLTVYGDGFDADACVENNVVSVA------GVNCVPVAC------TNTEITCRLEAVVGV--PESDLPRGLAGSIFSNSLGT ||..... . . || ..|..| ||. ... .|.| .|.| .. |.|.|.. . . . .. | . .... . .. DPVITRIHPNCGPCSGGTERITICGKNFDS--DIQVRFVRVNVGGRVWEVPCTFQPWDYHGKDSQTQIVCCTPPYHNQSPIPGQVPVRVTQEVQFCNDNV WTP-APAEVFNFT | . . | .. RTQLSWPQPFTYV |
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| TIG | 22411.AA | TIG | 820-911 | 24 | 2.1e-12 | 44.32 | Pfam | 1-82 (82) | Show / Hide |
Range on Protein: 820-911 Range on HMM: 1-82/82 Sequence Identity: 24% (23 aa) AQAVDAVGP-LTGPVAGNLLLNIAGTGFPASPAENNVTVGGQPCVVQSAQPDSLTCILPPAWSDLDTREADLNGTLNATIVING--EAFTNDFVY . .... | |||..|. .. | |..| .. .. ...||.||.| . .....|..||. .||.| .. .|| ...| | PT-ITSISPNTTGPPSGGTTITITGQNFGNDS-DTKCYFGGTPCTVIWWSSTQIVCTTPPHT----------PGTHNVSV-VNGQWSSNPTTFTY |
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| TIG | 22411.AA | TIG | 732-819 | 23 | 2.4e-12 | 44.15 | Pfam | 1-82 (82) | Show / Hide |
Range on Protein: 732-819 Range on HMM: 1-82/82 Sequence Identity: 23% (21 aa) PSINTVSNSGDP-SVLAV--ADIVTISGAGFGLDEAAIAVTFNDIPASIVQVSDTEVICEVPHISAGPINIELIRAHVGRAANHDATAWTY |.|. .| | . . ...||.| .|| | . ..|...|. .. .|.|...|..| ...|..|. . . . ... | || PTITSIS----PNTTGPPSGGTTITITGQNFGNDS-DTKCYFGGTPCTVIWWSSTQIVCTTPPHTPGTHNVSV-VNG---QWSSNPTTFTY |
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| IPT | 22411.AA | IPT | 731-820 | 16 | 0.015046 | 6.56 | SMART | 1-111 (111) | Show / Hide |
Range on Protein: 731-820 Range on HMM: 1-111/111 Sequence Identity: 16% (19 aa) NPSINTVSNSGDPSVLAVA--D-IVTISGAGFGLDEAAIAVTFN------DIPASIVQV------SDTEVICEVPHISA---GPINIEL---IRAHVGRA .|.| . .|. .. . ..|| | |. | . |..| |...... |.|. .|..|... .|.. .. .. . . DPVIT----RIHPNCGPCSGGTERITICGKNFDSDIQVRFVRVNVGGRVWEVPCTFQPWDYHGKDSQTQIVCCTPPYHNQSPIPGQVPVRVTQEVQF-CN ANHDA-----TAWTYA .| .. .|| DNVRTQLSWPQPFTYV |
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| IPT | 22411.AA | IPT | 823-912 | 16 | 0.017414 | 5.87 | SMART | 4-111 (111) | Show / Hide |
Range on Protein: 823-912 Range on HMM: 4-111/111 Sequence Identity: 16% (19 aa) VDAVGPLTGPVAGNL-LLNIAGTGFPASPAENNVTVG------GQPCVVQSA------QPDSLTCILPPAWSDLDTREADLNGTL----NATIVINGEAF . .. | .||..|. .. | |. | .. . |.|. ..|| .|.. . ...| .||. . . . .... .. . .|.. ITRIHPNCGPCSGGTERITICGKNFDSDIQVRFVRVNVGGRVWEVPCTFQPWDYHGKDSQTQIVCCTPPY--HNQSP-IPGQVPVRVTQEVQF-CNDNVR T-----NDFVYD | .| | TQLSWPQPFTYV |
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| TIG | 22411.AA | TIG | 917-940 | 28 | 1.760906 | 3.99 | Pfam | 1-25 (82) | Show / Hide |
Range on Protein: 917-940 Range on HMM: 1-25/82 Sequence Identity: 28% (7 aa) PVLTAVTP-SAIPSAVTTLVTLAGS |..|...| . |.. |..|. |. PTITSISPNTTGPPSGGTTITITGQ |
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| TIG | 22411.AA | TIG | 1028-1118 | 23 | 1.8e-07 | 27.63 | Pfam | 3-82 (82) | Show / Hide |
Range on Protein: 1028-1118 Range on HMM: 3-82/82 Sequence Identity: 23% (22 aa) VTAISP-ARFGTAGGARITITGAGFGQLVNSVGVEAKNVSGSNVPCLVDYVSDSQVECVMAEATGEAHDCELELQINGFVARCSPGTCVVDF .|.||| .. ..|| .||||| .| . . . ..|| | ..|..|..|. ..| . .. . .|| .|.... . ITSISPNTTGPPSGGTTITITGQNF-----GNDS-DTKCYFGGTPCTVIWWSSTQIVCTTPPHT-PG-THNVSV-VNG---QWSSNPTTFTY |
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| IPT | 22411.AA | IPT | 1025-1115 | 21 | 0.014301 | 6.8 | SMART | 1-111 (111) | Show / Hide |
Range on Protein: 1025-1115
Range on HMM: 1-111/111
Sequence Identity: 21% (24 aa)
NHRVTAISPARFGTAGGA-RITITGAGFGQLVNSVGVEAK-NVSGS-NVPCLVDYV------SDSQVECVMAEATG---EAHDCEL----ELQINGFVAR
. ..|.|.| . .|| ||||.| |. .... |. . . .||| .. . |..| .|.. .... . . .. |.|. . |
DPVITRIHPNCGPCSGGTERITICGKNFDSDIQVRFVRVNVGGR-VWEVPCTFQPWDYHGKDSQTQIVCCTPPYHNQSPIPGQVPVRVTQEVQFCNDNVR
C-----SPGTCV
.| | |
TQLSWPQPFTYV
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| TIG | 22411.AA | TIG | 1128-1203 | 23 | 3e-06 | 23.71 | Pfam | 1-82 (82) | Show / Hide |
Range on Protein: 1128-1203 Range on HMM: 1-82/82 Sequence Identity: 23% (20 aa) PS-------TERPSVGWGDVVTLTTERV---WGNPSVTVGGVPAVVQSYSETAVTFEVPALSAGAHDVALAVAPYGRASGMASLGY |. |. |. | |...|.| . ......||.|..| . |.| .....|....| |.| . | .. |. .. | PTITSISPNTTGPPSG-GTTITITGQNFGNDS-DTKCYFGGTPCTVIWWSSTQIVCTTPPHTPGTHNVSV-VNG-QWSSNPTTFTY |
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| TIG | 22411.AA | TIG | 1205-1295 | 14 | 2.8e-07 | 26.98 | Pfam | 1-82 (82) | Show / Hide |
Range on Protein: 1205-1295 Range on HMM: 1-82/82 Sequence Identity: 14% (14 aa) LSVDGLSQ-LSGSVAGGSRVVLVGEGFPTDPTALAVSFVHAGSGNNARRAAVLSTNMTLAEVVIPYLINEGTAHSETYELALTVTN-----SSTFQI .... .| .|...||..... |..| .|. . . | . .. ... |. ....| .. ..|... . | . ..||.. PTITSISPNTTGPPSGGTTITITGQNFGNDS-DTKCYFGGTPCTVI-------WWSSTQIVCTTPPHT------PGTHNVSV-VNGQWSSNPTTFTY |
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| TIG | 22411.AA | TIG | 1327-1391 | 36 | 1.2e-15 | 55.34 | Pfam | 1-69 (82) | Show / Hide |
Range on Protein: 1327-1391 Range on HMM: 1-69/82 Sequence Identity: 36% (26 aa) PVLTAIQP-TTGAA--GTVLTLTGSNF---FAEPRVHIAGVACTVLTANSSLVTCTVGEVRGGSHLVEVEV |..|.|.| ||| . ||..|.||.|| ...... |..||| . .|....||. .. .|.| | | | PTITSISPNTTGPPSGGTTITITGQNFGNDS-DTKCYFGGTPCTVIWWSSTQIVCTTPPHTPGTHNVSV-V |
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| IPT | 22411.AA | IPT | 1326-1404 | 18 | 3.4e-05 | 24.51 | SMART | 1-111 (111) | Show / Hide |
Range on Protein: 1326-1404
Range on HMM: 1-111/111
Sequence Identity: 18% (21 aa)
TPVLTAIQPTTGAAG--T-VLTLTGSNFFA---EPRVHIA------GVACTVLTA------NSSLVTCTVGEVRG---GSHLVEV----EVTPFGMAMGI
|| |.|.|..| . | ..|..|.|| . ...| . .|.||.. . ... .|.... .. . |.| || ... .
DPVITRIHPNCGPCSGGTERITICGKNFDSDIQVRFVRVNVGGRVWEVPCTFQPWDYHGKDSQTQIVCCTPPYHNQSPIPGQVPVRVTQEVQF-CNDNVR
H--------TFA
|.
TQLSWPQPFTYV
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| TIG | 22411.AA | TIG | 1407-1487 | 22 | 1.6e-12 | 44.77 | Pfam | 1-82 (82) | Show / Hide |
Range on Protein: 1407-1487 Range on HMM: 1-82/82 Sequence Identity: 22% (19 aa) ATVDSMSP-AIASYAGGTLVTLHGHGF-GPADAVSITVGTKSCDVVNTTYNQVLCRAPEVLTPLAVAYYAHVE-PVVLPGTMSY |..| || . .. .|||..|..|..| . . .....|. |.|. .. .|. |..|.. . . . .. |.| .| PTITSISPNTTGPPSGGTTITITGQNFGNDS-DTKCYFGGTPCTVIWWSSTQIVCTTPPHTPGTHNVSV-VNGQWSSNPTTFTY |
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| IPT | 22411.AA | IPT | 1406-1499 | 15 | 5.7e-07 | 30.4 | SMART | 1-111 (111) | Show / Hide |
Range on Protein: 1406-1499 Range on HMM: 1-111/111 Sequence Identity: 15% (18 aa) TATVDSMSPAIASYAGGT-LVTLHGHGFGP-ADAVSITVG------TKSCDVVNTTY------NQVLCRAPEVLTPLAVAYYAHVEPVVLPGTMSYEQLL .. ...| .. .||| ..|..|. |.. . ....|. . .| .... | .| .|..|. ... . . || ...... . DPVITRIHPNCGPCSGGTERITICGKNFDSDIQVRFVRVNVGGRVWEVPCTFQPWDYHGKDSQTQIVCCTPPYHNQSP---IPGQVPVRVTQEVQF-CND DRDYS-------TYV ... . ||| NVRTQLSWPQPFTYV |
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| TIG | 22411.AA | TIG | 1603-1614 | 38 | 13.639823 | 0.98 | Pfam | 1-13 (82) | Show / Hide |
Range on Protein: 1603-1614 Range on HMM: 1-13/82 Sequence Identity: 38% (5 aa) PVVTRIHP-AALP |..|.|.| . | PTITSISPNTTGP |
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| TIG | 22411.AA | TIG | 1648-1732 | 25 | 6.8e-16 | 56.17 | Pfam | 1-82 (82) | Show / Hide |
Range on Protein: 1648-1732 Range on HMM: 1-82/82 Sequence Identity: 25% (23 aa) PEVNAIRP-TWGTALGGTKITVLGLGL---TAVSSVTINTYPCSDISVVSDSLITCVTTRRSTLTALSVEVEVDDGSIAVNQPTARFRY | ...| | |.|.. |||.||. | .. . .........|| | ..|...|.|.| .. ..| | |.. . . . .|.| PTITSISPNTTGPPSGGTTITITGQNFGNDS-DTKCYFGGTPCTVI-WWSSTQIVCTTPPHTPG-THNVSV-VNG---QWSSNPTTFTY |
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| IPT | 22411.AA | IPT | 1647-1733 | 22 | 2e-06 | 28.95 | SMART | 1-111 (111) | Show / Hide |
Range on Protein: 1647-1733 Range on HMM: 1-111/111 Sequence Identity: 22% (25 aa) TPEVNAIRPTWGTALGGT-KITVLGLGLTA---VSSVTIN------TYPCSDIS--VV---SDSLITCVTTRRS----TLTALSV----EVEVDDGSIAV |.. .| |..| . ||| ||. | . . | .|..| . ||. .. . |.. |.|.| . . | || . ... DPVITRIHPNCGPCSGGTERITICGKNFDSDIQVRFVRVNVGGRVWEVPCTFQPWDYHGKDSQTQIVCCTPPYHNQSPIPGQVPVRVTQEVQF-CNDNVR NQ--PTARFRYM | .. .|.|. TQLSWPQPFTYV |
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| G8 | 22411.AA | G8 | 1740-1822 | 42 | 2.6e-29 | 108.48 | Pfam | 1-94 (137) | Show / Hide |
Range on Protein: 1740-1822 Range on HMM: 1-94/137 Sequence Identity: 42% (40 aa) NTWVNDEPPIEGDTVVIPADQVVLMDVT---PPKLFLLLV-QGQLIFEDM---QDLELHASYIWVQGG--LLEVGTEDVPF--QHRATITLYGD .|| | |..|| |.||| . ||.|| .||. ... ||||| | ....|.| .||..|| |..|||..|. ||..||||.|. STWQNGKVPQPGDNVTIPAGYTVLLDVNSIQTPKYKQIIIWEGQLIFADNRDGRNITLRAHWIWIMGGGFRLHIGTEECPYAWQHKITITLHGR |
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| G8 | 22411.AA | G8 | 1863-1881 | 47 | 0.011392 | 13.08 | Pfam | 119-137 (137) | Show / Hide |
Range on Protein: 1863-1881 Range on HMM: 119-137/137 Sequence Identity: 47% (9 aa) GVIDIHGIPRRRTWTKVAQ | |..|| ... |||| |. GTIELHGKQPHTTWTKLAA |
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| G8 | 22411.AA | G8 | 2584-2699 | 31 | 2.6e-17 | 68.61 | Pfam | 7-137 (137) | Show / Hide |
Range on Protein: 2584-2699 Range on HMM: 7-137/137 Sequence Identity: 31% (41 aa) TLPLAGDQVEIGVRMYVVMNIN---PPAFSHMDI-AGKLQFDDS---DDRMLEANTISVWG---ELQVGSSGKPF--EHEGVVRLHGQRTSDSLIIDDTH ..| .|| | | |.. .| .| .. | |.| |.|. . |.|. | ..| .|..|. . |. .|. . |||. .. .|.|. KVPQPGDNVTIPAGYTVLLDVNSIQTPKYKQIIIWEGQLIFADNRDGRNITLRAHWIWIMGGGFRLHIGTEECPYAWQHKITITLHGREDDTDFIQDNGP FLGNKVMAVL--GTVSMYG-QPRTAWVRLAA |||| .| ||....| ||.| | .||| YMGNKVIGVMNGGTIELHGKQPHTTWTKLAA |
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| SH2 | 22411.AA | SH2 | 3748-3831 | 17 | 0.000754 | 6.68 | SMART | 1-87 (87) | Show / Hide |
Range on Protein: 3748-3831 Range on HMM: 1-87/87 Sequence Identity: 17% (16 aa) NDYWHPKLSAAQAQEIIMD--KPQGTFLLYGRKP----VILCVKTGKNTARHDALEFHGDLGFRIQMKREQPFHGDLSTLIAYYAEPREG . | ..| ..|... . .| |.||. . . .|.|... . .| .. .| ...|. . . .| |...| .. | QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-GKVKHYRIRRNDDGKYYIDET-WRRKFPSL-ELVNHYQHNPLG |
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