Gene 11339 (M.brevicollis)
11339
Species: M.brevicollis
Alias: 11339
External Links:
Annotation:
Sequence
Protein domains of 11339.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| VWD | 11339.AA | VWD | 142-160 | 73 | 1.6e-07 | 27.58 | Pfam | 1-19 (163) | Show / Hide |
Range on Protein: 142-160 Range on HMM: 1-19/163 Sequence Identity: 73% (14 aa) CSATGDPHYRTFDGRYYHI ||. |||||.|||||||.. CSVWGDPHYTTFDGRYYTF |
|||||||||
| VWD | 11339.AA | VWD | 129-303 | 17 | 5e-06 | 23.75 | SMART | 1-185 (185) | Show / Hide |
Range on Protein: 129-303 Range on HMM: 1-185/185 Sequence Identity: 17% (36 aa) DIQFTTKQRPTAACSATGDPHYRTFDGRYYHI--RPNGKVVFYKS---KAENR----VFEVQTDMYRFNGR------PAVQCGLAAREGNDVVVISWCAT . . ....| ||. |||||.|||||||.. . | . |. . . .. | | .. . .. ... . ........|. WCCTQHECPCCATCSVWGDPHYTTFDGRYYTFPMPGNCYYVLAQDYPGQCTEWPHWPTFSVLMQNCNCGQDGKTDKHATCHKSVKVQLNDIDIHIK---- GHNIEYRLSCG-----STECDQGKWPRVGVTSS--SNPTYTIDFKSG--AQVKFDVHYWSAIGRRYMNLYVKAPGVDKGLTAGVCGNNDNNNNNDV--AV | . .. . . . .. . .. .... . ... .| || .| .....||. |. .| | | |||.... .| . --NMKVTVNGQRPPKVNLPYKHNDG-QIHIYRYQAGGYYVVVIHDFGYHIQVMWD---------GQTRFYVQVPPWYQGKTCGLCGNYNGEPRDDFMMPD G | G |
|||||||||
| VWD | 11339.AA | VWD | 271-299 | 31 | 0.027709 | 9.53 | Pfam | 128-156 (163) | Show / Hide |
Range on Protein: 271-299 Range on HMM: 128-156/163 Sequence Identity: 31% (9 aa) MNLYVKAPGVDKGLTAGVCGNNDNNNNND |..||... .. | | |||.... .| MQVYVWVSWMYQNQTCGLCGNYNGEPRDD |
|||||||||
| EGF_2 | 11339.AA | EGF_2 | 492-522 | 30 | 8.8e-09 | 30.95 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 492-522 Range on HMM: 1-29/29 Sequence Identity: 30% (11 aa) CPTSTEQPCSG-NGQCV---ETKCHCNAG-FLGADC | |.| .|.|. ||.|. | . |..| C-------CNGHHGTCNNQGCGKCQCDDGWWQGDHC |
|||||||||
| EGF | 11339.AA | EGF | 492-521 | 29 | 0.000402 | 16.84 | Pfam | 1-36 (36) | Show / Hide |
Range on Protein: 492-521 Range on HMM: 1-36/36 Sequence Identity: 29% (11 aa) CPTSTEQPCSGNGQCVET----KCHCNAG---FLGAD |. . ||...|.||.| .|.| | . | . CNPNN-NPCHHHGTCVDTPGGYTCQCPPGYLGYTGKR |
|||||||||
| TIG | 11339.AA | TIG | 551-621 | 18 | 1.8e-07 | 27.62 | Pfam | 19-82 (82) | Show / Hide |
Range on Protein: 551-621 Range on HMM: 19-82/82 Sequence Identity: 18% (13 aa) EVAIIGSNFYSNGSNVRCMFGDQVTSGTVLGSVEVRCRLPTNQHRSAPARSVPLRVSTDGGQTYSALNPAV .. |.|.|| .. ...|.||.. . .. | ...|..| | .....| ..|... . .. . TITITGQNFGNDS-DTKCYFGGTPCTVIWWSSTQIVCTTPPHT----PG-THNVSV-VNGQWSSNPTTFTY |
|||||||||
| EGF | 11339.AA | EGF | 638-651 | 42 | 11.68155 | 1.93 | Pfam | 1-14 (36) | Show / Hide |
Range on Protein: 638-651 Range on HMM: 1-14/36 Sequence Identity: 42% (6 aa) CSPNPASCFIDGQC |.||. | .|.| CNPNNNPCHHHGTC |
|||||||||
| CA | 11339.AA | CA | 718-797 | 17 | 0.000177 | 15.21 | SMART | 1-121 (121) | Show / Hide |
Range on Protein: 718-797
Range on HMM: 1-121/121
Sequence Identity: 17% (23 aa)
LLQSDPSH-------V------ITYSIQEGDDAEYFKIDPTSG-----------EVRLTQDIVVSESFA-------LSFRGYMIVVATDEQG--------
. .|| .|||| . .|.|||..| ....|. . | | ... ..|.||| |
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYT--LTVQATDGGGPPPPDSHP
---------QTAYVPVHVRLLAANEQPL
......|....| |. |
TRKFQQNPPLSSTCTVTIHVLDVNDNPP
|
|||||||||
| Cadherin | 11339.AA | Cadherin | 721-753 | 31 | 0.074645 | 9.15 | Pfam | 27-64 (102) | Show / Hide |
Range on Protein: 721-753 Range on HMM: 27-64/102 Sequence Identity: 31% (12 aa) SDPSHVITYSIQEGDD--AEYFKIDPTSGE---VRLTQ . | |.||| .|. . |.||| .|. ...|. LGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTK |
|||||||||
| Cadherin | 11339.AA | Cadherin | 770-790 | 20 | 0.583237 | 6.04 | Pfam | 78-102 (102) | Show / Hide |
Range on Protein: 770-790 Range on HMM: 78-102/102 Sequence Identity: 20% (5 aa) IVVATDE-Q---GQTAYVPVHVRLL .|.|||. . .......|.. .. TVMATDHDDGGPPRSSTTTVTITVC |
|||||||||
| CA | 11339.AA | CA | 820-899 | 19 | 1.8e-14 | 55.32 | SMART | 1-121 (121) | Show / Hide |
Range on Protein: 820-899
Range on HMM: 1-121/121
Sequence Identity: 19% (25 aa)
ITATDTDA-----FSN------LEYAFIVQEAGFAGAVTVNRTTG-----------QVTLNQALNYEEK---------SHYRFELQARDDGG--------
.|||| |. .. ..| .. .....|| ..|....|..||. ..|... ||.| ||
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHP
---------ASDFVEVRFFVTDVNEAPT
|. ..|. .|.|||. |
TRKFQQNPPLSSTCTVTIHVLDVNDNPP
|
|||||||||
| Cadherin | 11339.AA | Cadherin | 803-892 | 19 | 4.1e-12 | 44.88 | Pfam | 1-102 (102) | Show / Hide |
Range on Protein: 803-892 Range on HMM: 1-102/102 Sequence Identity: 19% (20 aa) LNFTFPESTQPGYTIGQITATDTD----AFSNLEYAFIVQEAGFAGAVTVNRTTGQ---VTLNQALNYEEK-SHYRFELQARDD-G---GASDFVEVRFF .|...| ...| .....|||| | . ... |... .. .. .... ||. .|. . |..|. . |.. . |.| . . |. ..|. YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT VT |. VC |
|||||||||
| CA | 11339.AA | CA | 920-993 | 20 | 1.2e-05 | 25.96 | SMART | 1-121 (121) | Show / Hide |
Range on Protein: 920-993 Range on HMM: 1-121/121 Sequence Identity: 20% (25 aa) LSAVDEDF----VDSH-------TFTVLAGDFAVAD--G-----------KLYTTKAFDYENP-------AERQTSVTLRATDKGG-------------- ..|.|.| .. |.... |.. . | ..|||..|.|. .. | ..| .|||.|| VTATDPDEGHNGPNGQPNDPEMVTYSIVG-WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKFQQ ---LTFDKTLTITITNVNEPPT |. |.||... ||. | NPPLSSTCTVTIHVLDVNDNPP |
|||||||||
| Cadherin | 11339.AA | Cadherin | 904-986 | 23 | 0.001239 | 15.35 | Pfam | 1-102 (102) | Show / Hide |
Range on Protein: 904-986 Range on HMM: 1-102/102 Sequence Identity: 23% (24 aa) NSTQVPENGV-DVLVGVLSAVDED---FVDSHTFTVLAGDFA---------VADGK---LYTTKAFDYENPAERQTSVTLRATDK-G---GLTFDKTLTI . .|.|| . |... |.| | . | . |. ..| ..||| |.| . ..| ..|..||| . ... |.|| YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQ-NGQYHLTVMATDHDDGGPPRSSTTTVTI TIT |.. TVC |
|||||||||
| CA | 11339.AA | CA | 1016-1090 | 14 | 0.000526 | 10.37 | SMART | 1-121 (121) | Show / Hide |
Range on Protein: 1016-1090
Range on HMM: 1-121/121
Sequence Identity: 14% (18 aa)
ITVTDPDV-----NDV------IACALVDDDEGRFAVLGQ-------------VLKLVKAFNYEAA---------AAHALTIACFDEAG-----------
.|.|||| | . . .|. |.. . .....|....|. . . ||. | .|
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK
------AQVDRSFVITVTDEQEAPQ
. ...|.|.|. . |
FQQNPPLSSTCTVTIHVLDVNDNPP
|
|||||||||
| Cadherin | 11339.AA | Cadherin | 998-1083 | 20 | 8.424655 | 2.0 | Pfam | 1-98 (102) | Show / Hide |
Range on Protein: 998-1083 Range on HMM: 1-98/102 Sequence Identity: 20% (20 aa) DQTTFAETQMRPGEDLAIITVTDPD----VNDVIACALVDDD---EGRFAVLG--QV---LKLVKAFNYEAA-AAHALTIACFDEAGAQVDRSFVITVT . .. |.. .| .. .|.|||| | | ... .. .. |.. . ....| ..|. . ||. . |..... || . ||| YHFSVCENAP-VGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVT |
|||||||||
| Cadherin | 11339.AA | Cadherin | 1095-1126 | 38 | 0.000817 | 15.98 | Pfam | 1-34 (102) | Show / Hide |
Range on Protein: 1095-1126 Range on HMM: 1-34/102 Sequence Identity: 38% (13 aa) NQVVVAEDAPVGTKVGVITAEDQD--ADAGAMTF .. | |.|||||.|...|| | | . .. | YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIF |
|||||||||
| CA | 11339.AA | CA | 1112-1200 | 17 | 0.000934 | 7.82 | SMART | 1-121 (121) | Show / Hide |
Range on Protein: 1112-1200
Range on HMM: 1-121/121
Sequence Identity: 17% (22 aa)
ITAEDQDA----DAGA------MTFAMADPEAPFELKNTQCG----LAAGRMVCSVDVFTTGPLDADLDG--------GVMSILVRATDNND--------
.|| | |. . | |. . . .|.. . | | ....||.||| . . .. |.|||..
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSL----VYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHP
---------MAAMKELQLKVENVNEPPS
. . ... .|. ||. |
TRKFQQNPPLSSTCTVTIHVLDVNDNPP
|
|||||||||
| Cadherin | 11339.AA | Cadherin | 1207-1234 | 25 | 7.001521 | 2.28 | Pfam | 1-31 (102) | Show / Hide |
Range on Protein: 1207-1234 Range on HMM: 1-31/102 Sequence Identity: 25% (8 aa) QTPTVREDAADGAVVGRLVVADED---AVNA .. .|.|.|. | |... . | | . |. YHFSVCENAPVGTFVMTVTATDPDDPLGPNW |
|||||||||
| Cadherin | 11339.AA | Cadherin | 1287-1318 | 27 | 1.050383 | 5.15 | Pfam | 66-102 (102) | Show / Hide |
Range on Protein: 1287-1318 Range on HMM: 66-102/102 Sequence Identity: 27% (10 aa) LNAETM-QGYMLSVRVTDE-G---GLSAALDAPITIE |. |.. . | |.|..||. . ..|. ||.. LDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTITVC |
|||||||||
| Cadherin | 11339.AA | Cadherin | 1332-1351 | 30 | 7.833986 | 2.11 | Pfam | 1-20 (102) | Show / Hide |
Range on Protein: 1332-1351 Range on HMM: 1-20/102 Sequence Identity: 30% (6 aa) AVAAVAENEPAQTVVGQLAV .. | ||.| .| |..... YHFSVCENAPVGTFVMTVTA |
|||||||||
| Cadherin | 11339.AA | Cadherin | 1508-1534 | 25 | 4.709548 | 2.88 | Pfam | 72-102 (102) | Show / Hide |
Range on Protein: 1508-1534 Range on HMM: 72-102/102 Sequence Identity: 25% (8 aa) PGNYKVTITAKSS-D---GLESSHQLTLRVA .| | .|. |. . | ...| ..| | NGQYHLTVMATDHDDGGPPRSSTTTVTITVC |
|||||||||
| SH2 | 11339.AA | SH2 | 1627-1707 | 32 | 1.2e-17 | 53.62 | Pfam | 1-81 (81) | Show / Hide |
Range on Protein: 1627-1707 Range on HMM: 1-81/81 Sequence Identity: 32% (28 aa) WYAPDLTRQDAAGELTD--RPDGAFVVRDSKATPGWHILGVKAGN---QVLHEKIRRDEEGLYELVPSNNEPQPAFYSLPDLIHYY || ....||.| | |||.|.||.| ||| | |. .. .| | .|.|...| . . .. | ||..|...| WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNG--GYYITGRHK---FCSLQELVEHY |
|||||||||
| SH2 | 11339.AA | SH2 | 1625-1713 | 31 | 4.2e-16 | 60.73 | SMART | 1-87 (87) | Show / Hide |
Range on Protein: 1625-1713 Range on HMM: 1-87/87 Sequence Identity: 31% (29 aa) YEWYAPDLTRQDAAGELTD--RPDGAFVVRDSKATPGWHILGVKAGNQVLHEKIRRDEEGLYELVPSNNEPQPAFYSLPDLIHYYGSQREE ..|| ...|..| | |||.|.|||| .|| .| |. ...| | .|||...| | . . . . | || .|...| . QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDET---WRRKFPSL-ELVNHYQHNPLG |
|||||||||