Gene 12682 (M.brevicollis)

12682

Species: M.brevicollis
Alias: 12682
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: TNS1

Sequence

Name Sequence Type Origin Length Description Download
12682.AA Protein None 843 None Fasta, JSON

Protein domain

Protein domains of 12682.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C1 12682.AA C1 71-118 18 3e-06 27.95 SMART 1-61 (61) Show / Hide 
Range on Protein: 71-118
Range on HMM: 1-61/61
Sequence Identity: 18% (11 aa)

HVFVEGQGFGKPCRICTDRVWRR--------AAMCTNCRYICHERCIGQARK-----HLDC
| ....   .. |..| ...|          . .|..|.| ||..|  .. .      ..|
HHWHWWRFKPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
PTPc_motif 12682.AA PTPc_motif 207-299 15 0.000153 4.61 SMART 1-92 (92) Show / Hide 
Range on Protein: 207-299
Range on HMM: 1-92/92
Sequence Identity: 15% (16 aa)

FHNQVLDFGWPDH-----MAPSLERLASICNSIDSWIEADPNNVIAVHCKGGKGRTA-------LSTNSPSFGADIISFTSDKKSSGITNPSQRRYVLYF
.....   .||||      .|. . . ...... .         | |||  | |||.       .  .      ...    . .   ...  |  |.   
TVHHYHYTNWPDHVEKDSGVPE-DSILEFIRHVRK--------PIVVHCSAGCGRTGTFCAIDMMMQQ--VDIFQTVKEMRKQRPGMVQTEEQ--YIFCY

EAVLA
...| 
RCILE
PTEN_C2 12682.AA PTEN_C2 304-396 31 3.7e-17 63.6 Pfam 1-101 (141) Show / Hide 
Range on Protein: 304-396
Range on HMM: 1-101/141
Sequence Identity: 31% (32 aa)

VYRKHLVLEHVYL-QGIPAFDGSGGC-RPYLS-IMEDFRV--VYQSPEPIRTFRRDDKFIQFDLDQGLHLAGDVVIECYHRP-S---RGADVLMFRIQFP
 ..| | | .... .||| |.. ||| |||.  ...|  |   ... .. .   ...| . |...|.....|||.|.|||.  |      ...|||..| 
PPPKPLFLHCIIMDHGIPNFKQGGGCWRPYIQIYQNDQKVFYTCKKYWHCKKY-KQQKCCIFKFPQPCPVQGDVKIQCYHKGPSDLPWMYEECMFRFWFN

TC
||
TC
SH2 12682.AA SH2 687-773 23 4.7e-08 33.99 SMART 1-87 (87) Show / Hide 
Range on Protein: 687-773
Range on HMM: 1-87/87
Sequence Identity: 23% (21 aa)

CAWYFADFTKEATDRLLLEK-GQPGEFVVRR-DPLDSHTFYLSVRCPESVVVHLLVQWVPRQQQFELDH--RACFADMQQLIKFYSSNTVA
. ||. . ..|  ..||.   ...| |.||  .. .   . ||||.  . | | ...  .   .. .|   | .| .  .|. .|. |   
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWK-GKVKHYRIRRNDD-GKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 12682.AA SH2 689-767 25 3e-06 20.24 Pfam 1-81 (81) Show / Hide 
Range on Protein: 689-767
Range on HMM: 1-81/81
Sequence Identity: 25% (22 aa)

WYFADFTKEATDRLLLE-KGQPGEFVVRRDPLDSHT----FYLSVRCPE--SVVVHLLVQWVPRQQQFELDHRACFADMQQLIKFY
||. . ...   |||..  ...| |.||    .| .    . ||||.    ..| |  .|. ..  .. .  | .|.. |.|. .|
WYHGKISRQEAERLLMNPGNPDGTFLVR----ESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNG-GYYITGRHKFCSLQELVEHY