26003

Species: M.brevicollis
Alias: 26003
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
26003.AA Protein None 842 None Fasta, JSON

Protein domain

Protein domains of 26003.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 26003.AA SH2 57-145 26 0.000188 13.14 SMART 1-87 (87) Show / Hide
Range on Protein: 57-145
Range on HMM: 1-87/87
Sequence Identity: 26% (24 aa)

QPWLQPNAPRDAIHEFLLL--QSQGDFVIYK-DPKTQTTHLAVQNGTGVDHFAIIENEEQKFQAAVDHSYAVQPTFESLEALVKFYQRRDLN
|||   | .|.  .. |.   .  |||..   ... .   | |  . .| |. | .|.. |.  . .      ..|.||  || .||.  | 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDET----WRRKFPSL-ELVNHYQHNPLG

SH2 26003.AA SH2 127-139 46 0.951519 4.02 Pfam 69-81 (81) Show / Hide
Range on Protein: 127-139
Range on HMM: 69-81/81
Sequence Identity: 46% (6 aa)

PTFESLEALVKFY
..|.||  || .|
HKFCSLQELVEHY

SH2 26003.AA SH2 550-639 23 6.7e-05 17.92 SMART 1-87 (87) Show / Hide
Range on Protein: 550-639
Range on HMM: 1-87/87
Sequence Identity: 23% (22 aa)

PLWVHGTYLNRDKAEQLLVRFGRGQGLFLVRERQLRDANDACRFCLSLVIDHGIEHHLIADNG-TMYSMPG--SKQFRTVRQASDLSSILMQI
  | ||  ..|..||||| . |   | ||||...     ..  ..||.  . .. | .|  |.  .|.  .  ...| .. .  .  .   . 
QPWYHG-NISREEAEQLLKNPGMPDGDFLVRDSES----NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG

SH2 26003.AA SH2 552-626 30 0.000511 13.62 Pfam 1-74 (81) Show / Hide
Range on Protein: 552-626
Range on HMM: 1-74/81
Sequence Identity: 30% (24 aa)

WVHGTYLNRDKAEQLLVRFGRGQGLFLVRERQLRDANDACRFCLSLVIDH---GIEHHLIADNGTM-YSMPGSKQFRTV
| ||  ..| .||.||   |   | |||||..    .|   . ||.. |     ..|  |  .... | . | ..|...
WYHG-KISRQEAERLLMNPGNPDGTFLVRESES-TPGD---YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSL

SH2 26003.AA SH2 665-762 23 1e-11 46.16 SMART 1-87 (87) Show / Hide
Range on Protein: 665-762
Range on HMM: 1-87/87
Sequence Identity: 23% (24 aa)

PDFFHGKIDRHEANRRLRIDGGNAEGHYLVRVSSNVHGSANSGAAAAFVISVVSNKLPMHHVVRRDG-NHWVLND--AFKFPHNCINLTDVLSFLMHPLA
  ..||.|.|.|| . |.   |. .| .||| |..         . ..|.|| ...   | ..||.. . ... .    |||     | . . . .|.  
QPWYHGNISREEAEQLLKNP-GMPDGDFLVRDSES--------NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPS----L-ELVNHYQHNPL

H
 
G

SH2 26003.AA SH2 667-732 31 1.7e-10 32.62 Pfam 1-60 (81) Show / Hide
Range on Protein: 667-732
Range on HMM: 1-60/81
Sequence Identity: 31% (22 aa)

FFHGKIDRHEANRRLRIDGGNAEGHYLVRVSSNVHGSANSGAAAAFVISVVSNK---LPMHHVVRRDGN
..|||| |.|| |.|.  .|| .| .||| |..  |.        ...||. .       | ...|..|
WYHGKISRQEAERLLMN-PGNPDGTFLVRESESTPGD--------YTLSVRDDGPGDRVKHYRIQRTDN