27106

Species: M.brevicollis
Alias: 27106
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
27106.AA Protein None 762 None Fasta, JSON

Protein domain

Protein domains of 27106.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C2 27106.AA C2 28-153 13 1.3e-05 25.87 SMART 1-92 (92) Show / Hide
Range on Protein: 28-153
Range on HMM: 1-92/92
Sequence Identity: 13% (19 aa)

VLTIQAHRARDLFNGVVDPSLKFQLRVHLVPRAEPAVLVHTLFKPLRPPRDSPFKKSSKIHAGTC---CPIFNE---VFQWQLEKLHGHEIEFQVAVALV
.||.  ..||.|     ||  |..                                 .|.. .|.   .|..||    |.  .     . ..|.|     
TLTVHIIEARNLP----DPYVKVY--------------------------------KTKVVKNTLSGFNPVWNEWMETFYFDVHP---Q-LRFEVWDH--

SSEPMSSSGSLCAGCFVLP--------------LHQLASTQHAVRR
             |....|              | ..   ..  . 
----------DFIGHCCIPPNNPHWHQWDGCIHLSDIL-GYRH-WW

C2 27106.AA C2 82-116 27 0.000536 16.09 Pfam 39-74 (90) Show / Hide
Range on Protein: 82-116
Range on HMM: 39-74/90
Sequence Identity: 27% (10 aa)

KKSSKIHAGTCCPIFNEVFQWQ--LEKLHGHEIEFQV
|. .|.. .|..|..|| |...  ...|.  ...|.|
KYKTKVIKNTLNPVWNETFTFDVPPPDLQH-TLRFTV

SH2 27106.AA SH2 646-711 28 1.5e-09 29.87 Pfam 1-70 (81) Show / Hide
Range on Protein: 646-711
Range on HMM: 1-70/81
Sequence Identity: 28% (20 aa)

WLHGAISKVEADEALEL-RKIDGQFLLRQRSPDSEDIVMSLTFRG---KPTHHLVMRDAGGRWLINRKQY
| || ||. || . |   .. || ||.|...    |.. |. . |   . .|  ..|...| . |  ...
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHK

SH2 27106.AA SH2 644-731 26 4.4e-07 30.79 SMART 1-87 (87) Show / Hide
Range on Protein: 644-731
Range on HMM: 1-87/87
Sequence Identity: 26% (24 aa)

RTWLHGAISKVEADEALELR-KIDGQFLLRQRSPDSEDIVMSLTFRGKPTHHLVMRDAGGRWLINRKQYGPPTDDLDNLLRLLAASQPP
  | || ||. ||.. |  . . || ||.|.....  |.| |. ..||  | .. |.. |.. |     ... ..|  |..       .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDET-WRRKFPSL-ELVNHYQHNPLG