33139

Species: M.brevicollis
Alias: 33139
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
33139.AA Protein None 615 None Fasta, JSON

Protein domain

Protein domains of 33139.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 33139.AA SH2 245-286 25 0.002493 11.6 Pfam 39-81 (81) Show / Hide
Range on Protein: 245-286
Range on HMM: 39-81/81
Sequence Identity: 25% (11 aa)

FSLIFKDDQENLVTQ-TIECEDN-QFLYLGGRRFDSFYNLVSYY
.|. .... .. |.   | ..|| .. . |...|.| . ||..|
LSVRDDGP-GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY

SH2 33139.AA SH2 312-426 21 5.1e-14 53.83 SMART 1-87 (87) Show / Hide
Range on Protein: 312-426
Range on HMM: 1-87/87
Sequence Identity: 21% (25 aa)

QTWFKVDMNSRQAELHLAKPALPDGAFVIRAATRSAGVFLLSIRAERIVSHSGSTSSTTGRDDAKLILKLTESKSPIVHHRLIFFEP-CGFRLQN-TERH
| |.  ...  .||  | .|  |||.|..|   ...| . ||.| .                               |.| .|. ..  .....  ..| 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-----------------------------GKVKHYRIRRNDDGKYYIDETWRRK

FSTLQALVDLYSVDPDR
|..|  ||. |.  |..
FPSL-ELVNHYQHNPLG

SH2 33139.AA SH2 314-420 22 7e-06 19.14 Pfam 1-81 (81) Show / Hide
Range on Protein: 314-420
Range on HMM: 1-81/81
Sequence Identity: 22% (24 aa)

WFKVDMNSRQAELHLAKPALPDGAFVIRAATRSAGVFLLSIRAERIVSHSGSTSSTTGRDDAKLILKLTESKSPIVHHRLIFFEPCG--FRLQNTERHFS
|.  ...  .|| .| .|  |||.|..|   .. | . || | .                            .. |.|  | ... |  ..  ..   |.
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP--------------------------GDRVKHYRIQRTDNGGYYITGRHK--FC

TLQALVDLY
.|| ||. |
SLQELVEHY

SH2 33139.AA SH2 529-608 18 3e-06 28.24 SMART 1-87 (87) Show / Hide
Range on Protein: 529-608
Range on HMM: 1-87/87
Sequence Identity: 18% (16 aa)

PDWNQLGVSTTQALSKLQAL---DGSFVVRRSP--FACASMTVVHKNSKYNFLIYHDS-KGFRFAH--QPSEPTLDALIAKHRQAHIR
  |    .|  .| ..|..    ||.|.|| |     . . .| .|.  ....| ..  ......    .. |.|  |.. ...  ..
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG