33487

Species: M.brevicollis
Alias: 33487
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
33487.AA Protein None 392 None Fasta, JSON

Protein domain

Protein domains of 33487.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 33487.AA SH2 30-106 45 6.2e-30 89.7 Pfam 1-81 (81) Show / Hide
Range on Protein: 30-106
Range on HMM: 1-81/81
Sequence Identity: 45% (37 aa)

YMHGKISREEVDALVRSNGFSEGLFLVRESARTPGDYALSVVAQG---KLQHFKISRKTGL-YRIDDGPGFGSLDELVQFY
. ||||||.|.  | .. |  .| |||||| .|||||.|||. .|   . .|..| |  .  | | ... |.|| |||..|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY

SH2 33487.AA SH2 28-112 44 7.6e-28 99.75 SMART 1-87 (87) Show / Hide
Range on Protein: 28-112
Range on HMM: 1-87/87
Sequence Identity: 44% (39 aa)

PPYMHGKISREEVDALVRSNGFSEGLFLVRESARTPGDYALSVVAQGKLQHFKISRKT-GLYRIDD--GPGFGSLDELVQFYRNPDDR
 |. ||.|||||...| ...|  .| ||||.| ..||||.|||  .|| .|..| |.  | |.||.  .. | || |||..|. . ..
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG

CH 33487.AA CH 271-349 24 3.4e-09 36.7 Pfam 1-87 (119) Show / Hide
Range on Protein: 271-349
Range on HMM: 1-87/119
Sequence Identity: 24% (22 aa)

EKMYLVWINDHLEQVG--MSPVS--DL-TDSLKNGVAVIKALESVSKETGIKPPHFHKNPRAFP----QEIDNWNIVIKYMRK-LGIPV
|| .| |.|.|||. |   .|..  .. ......||| .. ..... ...|..... ..||       . ..| | ... ..| ||.|.
EKAFLRWCNRHLEKYGHWGVPITPVNFFFTDWRDGVALCALIHKYCPGLLIDWKKV-FPPR-MRKMPFHCMENINYALDFCEKKLGCPC

CH 33487.AA CH 270-389 16 0.000242 17.31 SMART 1-100 (100) Show / Hide
Range on Protein: 270-389
Range on HMM: 1-100/100
Sequence Identity: 16% (20 aa)

EEKMYLVWINDHLEQVGMSPVSDLTDSLKNGVAVIKALESVSK-ETGIKPPHFHKNPRAFPQEIDNWNIVIKYMRKL----GIPVDEEGTGEEYVAPLDP
.|. .| |.|.||      ||.......|.||. .. .....  ..  .         .| . ..| | ... ..|.    |..  .  ..|. | . . 
QEETFLRWCNSHL------PVNNFSTDWKDGVVLCQLINKIRPQDSIDWWH-------RF-HCMENINYFLNFCEKYGMFLGVCCVVNFDPEDIVDGNN-

AALHNADRREMLKLFSKLLMYEASL
            |.. .....  .|
----------NRKDILGVIWCLMQL