Gene 33651 (M.brevicollis)

33651

Species: M.brevicollis
Alias: 33651
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Unique

Sequence

Name Sequence Type Origin Length Description Download
33651.AA Protein None 2443 None Fasta, JSON

Protein domain

Protein domains of 33651.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 33651.AA SH2 10-96 26 1.6e-05 24.66 SMART 1-87 (87) Show / Hide 
Range on Protein: 10-96
Range on HMM: 1-87/87
Sequence Identity: 26% (24 aa)

SPWFAAGKLDHRAAVQALTSVDLREGAFLVRRSNT-GDHLVLCYANAEGQVKNEQIVLGR-SGIRLKR-SKTSFPVLSELISFYCNPNNR
 ||.  |...   |.| | ..  ..|.|||| | .   ..||..    |.||. .|     .. ..   ....|| | ||. .|  .  .
QPWY-HGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SAM_2 33651.AA SAM_2 294-305 25 16.15219 1.2 Pfam 1-12 (71) Show / Hide 
Range on Protein: 294-305
Range on HMM: 1-12/71
Sequence Identity: 25% (3 aa)

EEYWKPSNTADW
..|| ......|
VHYWTFEDVCEW
SAM 33651.AA SAM 311-378 30 3.7e-11 44.3 SMART 1-67 (67) Show / Hide 
Range on Protein: 311-378
Range on HMM: 1-67/67
Sequence Identity: 30% (21 aa)

VEAWLESDVQQWLHNIGMSHRAKAFEDAAIDGEALLQLEGDQDRLAELGL-SHREQRTFHKELAALPKR
|. | ..||..||  |||.. ...|... |||..||||. ... | |.|  .   .. . |..  . ..
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLT-SHEDLKEMGITNPGHRKKILKAIQKMKDQ
Sam7 33651.AA sam7 314-376 23 1.7e-10 35.21 In-house 1-70 (70) Show / Hide 
Range on Protein: 314-376
Range on HMM: 1-70/70
Sequence Identity: 23% (17 aa)

WLESDVQQWLHNIGM---SHRAKAFEDAAI-----DGEALLQLEGDQDRLAELGLSHR-EQRTFHKELAALP
| ..||..||. |||   .. ...| |. |     ||..|....   . |.|.| .    .. .....  . 
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTE--EDLMEMGITRPGHRKKIWNHIQQMR
SAM_2 33651.AA SAM_2 311-359 31 3.5e-08 30.91 Pfam 1-53 (71) Show / Hide 
Range on Protein: 311-359
Range on HMM: 1-53/71
Sequence Identity: 31% (17 aa)

VEAWLESDVQQWLHNIGM-SHRAKAFEDAAIDG-EALLQLEGDQDRL--A-ELG
|. |  .||..||..|||  . . .|... |.| |.|. .  ..| |  . ..|
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLY-AHMTHDDLAMKNRMG
SAM_1 33651.AA SAM_1 312-348 36 0.00013 19.34 Pfam 1-38 (66) Show / Hide 
Range on Protein: 312-348
Range on HMM: 1-38/66
Sequence Identity: 36% (14 aa)

EAWLESDVQQWLHNIGMSHRAKAF-EDAAIDGEALLQL
. |  .||..||. |||.. ...| ..  ||...|||.
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQM
Sam7 33651.AA sam7 408-471 16 0.015345 7.01 In-house 1-70 (70) Show / Hide 
Range on Protein: 408-471
Range on HMM: 1-70/70
Sequence Identity: 16% (12 aa)

WDQYEVRNWALYEGL--PEGIAFKLAHGGV-----TGPLLLELNEEKLGALDIDPFAEPAQRLLDLVDAMD
|.. .|  |    |.   .  . ..   |.     .| .|....|| | .. |     ......  .. | 
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPG-HRKKIWNHIQQMR
Sam7 33651.AA sam7 494-555 21 1.8e-08 28.07 In-house 1-70 (70) Show / Hide 
Range on Protein: 494-555
Range on HMM: 1-70/70
Sequence Identity: 21% (15 aa)

WTPDHVYRFMMDTGF---GEQAATFRAHRI-----NGRALLALKSHALAELGLTSAADQEAFQAVVKQAY
||...|. .. . |.   .. . .||.|.|     .|..|. ..   |.|.| |.   .  .   ..|  
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM 33651.AA SAM 491-557 26 8.3e-07 29.86 SMART 1-67 (67) Show / Hide 
Range on Protein: 491-557
Range on HMM: 1-67/67
Sequence Identity: 26% (18 aa)

VEAWTPDHVYRFMMDTGFGEQAATFRAHRINGRALLALK-SHALAELGLTSAADQEAFQAVVKQAYDE
|. |||. | .. .  |... . .||...| |..||.|     | |.| |.. ..  ..  ...  |.
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
SAM_1 33651.AA SAM_1 492-544 21 3.8e-05 21.24 Pfam 1-55 (66) Show / Hide 
Range on Protein: 492-544
Range on HMM: 1-55/66
Sequence Identity: 21% (12 aa)

EAWTPDHVYRFMMDTGFGEQAATF-RAHRINGRALLALKSHALAE-LGLTSAADQ
. |... |  .. . |... . .| ||..|....|| ..   | . .| |.. ..
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDLMKHMGVTLPGHR
SAM_2 33651.AA SAM_2 491-555 19 0.003958 13.59 Pfam 1-71 (71) Show / Hide 
Range on Protein: 491-555
Range on HMM: 1-71/71
Sequence Identity: 19% (14 aa)

VEAWTPDHVYRFMMDTGF-GEQAATFRAHRING-RAL-LALKSHAL--A-ELGLTSAADQEAFQAVVKQAY
|. ||.. |  .    |. .. .  ||.| | | ..| . ...  |  . ..| |.. ..      ...  
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
Sam7 33651.AA sam7 567-629 17 3e-06 20.37 In-house 1-70 (70) Show / Hide 
Range on Protein: 567-629
Range on HMM: 1-70/70
Sequence Identity: 17% (12 aa)

WPLDKLLLHLEQQGV--SPHAVRALDEHQI-----KPAAFLQMQPQDLRAIGIKNPEEQQHLMEIAAKLL
|. . .   ||  |    .. . .. .| |       .....|  .||...||..|  ......   .. 
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM 33651.AA SAM 564-631 20 0.020748 9.03 SMART 1-67 (67) Show / Hide 
Range on Protein: 564-631
Range on HMM: 1-67/67
Sequence Identity: 20% (14 aa)

ATLWPLDKLLLHLEQQGVSPHAVRALDEHQIKPAAFLQMQ-PQDLRAIGIKNPEEQQHLMEIAAKLLNS
.  |. . .   ||  | .   . .. ...|  ...||.   .||  .||.||  .. ..    |....
VD-WTPEDVCDWLESIGMCQ-YKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
SAM_2 33651.AA SAM_2 564-629 15 0.106775 8.68 Pfam 1-71 (71) Show / Hide 
Range on Protein: 564-629
Range on HMM: 1-71/71
Sequence Identity: 15% (11 aa)

ATLWPLDKLLLHLEQQGVSPHAVRALDEHQIKP-AAF-LQMQPQDL--R-AIGIKNPEEQQHLMEIAAKLL
   | .. .   |.. |  .. . .. .|.|    .  ..|  .||    ..|| |.  .....  . ...
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
SAM_1 33651.AA SAM_1 598-615 36 0.727329 6.07 Pfam 34-52 (66) Show / Hide 
Range on Protein: 598-615
Range on HMM: 34-52/66
Sequence Identity: 36% (7 aa)

AFLQMQPQDLRA-IGIKNP
..||| ..||.. .|...|
CLLQMTWEDLMKHMGVTLP
Sam7 33651.AA sam7 658-719 28 8.6e-11 36.28 In-house 1-70 (70) Show / Hide 
Range on Protein: 658-719
Range on HMM: 1-70/70
Sequence Identity: 28% (20 aa)

WTPEDVSTWLEAIDL---QHIAPVMRQFDV-----DGPKLLTLQHEDLDAMDIVDQTDLEILREELQVLW
||.|||. |||.|..   |. .. .|....     ||  |. . .||| .| | .      . ...| . 
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM_2 33651.AA SAM_2 655-718 26 1.4e-08 32.3 Pfam 1-71 (71) Show / Hide 
Range on Protein: 655-718
Range on HMM: 1-71/71
Sequence Identity: 26% (19 aa)

VLLWTPEDVSTWLEAIDL-QHIAPVMRQFDVDG-PKL-LTLQHEDL--D-AMDIVDQTD-LEILREELQVL
|  ||.|||. ||..|.. .. .. .||. ..|   | . . |.||    .| | .. . ..|...  ...
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
SAM 33651.AA SAM 655-721 36 3.1e-08 34.62 SMART 1-67 (67) Show / Hide 
Range on Protein: 655-721
Range on HMM: 1-67/67
Sequence Identity: 36% (25 aa)

VLLWTPEDVSTWLEAIDLQHIAPVMRQFDVDGPKLLTLQ-HEDLDAMDIVDQTDLEILREELQVLWDR
|  ||||||. |||.|.... ..  |.  .||  || |  ||||  | | .  .   .  ..| . |.
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
SAM_1 33651.AA SAM_1 656-700 36 6.6e-07 27.45 Pfam 1-47 (66) Show / Hide 
Range on Protein: 656-700
Range on HMM: 1-47/66
Sequence Identity: 36% (17 aa)

LLWTPEDVSTWLEAIDLQHIAPVM-RQFDVDGPKLLTLQHEDLDA-M
  |..|||. |||.|..|. ..   |.  .|. .|| .  ||| . |
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDLMKHM
PDZ 33651.AA PDZ 739-819 32 7.3e-15 53.48 Pfam 1-86 (86) Show / Hide 
Range on Protein: 739-819
Range on HMM: 1-86/86
Sequence Identity: 32% (28 aa)

DVTLYRD-VNGRFGFHVGGGEGHDVSKAYLVTMVTPN-GAAHDK--LQPGDEIISVNGRYIDQSSLDHLRSLIKRCKS-ELMLRIR
.||| ..  .|..|| . ||....  .   .. | |. |||. .  ...|| |||.||. |   ..|    .||..|. |. | |.
QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ
PDZ 33651.AA PDZ 748-822 23 1.6e-11 45.48 SMART 1-80 (80) Show / Hide 
Range on Protein: 748-822
Range on HMM: 1-80/80
Sequence Identity: 23% (21 aa)

GRFGFHVGGGEGHDVSKAYLVTMVTPNGAAHDK-------LQPGDEIISVNG-RYIDQSSLDHLRSLIKRCKS-----ELMLRIRRPV
| .|| . |          ... | |.|.|.         |.|||.|..|||   ..  . .    ..|.|.      .. | ..|| 
GGLGFSIVG--------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG
SAM 33651.AA SAM 1011-1077 20 0.004192 15.83 SMART 1-67 (67) Show / Hide 
Range on Protein: 1011-1077
Range on HMM: 1-67/67
Sequence Identity: 20% (14 aa)

PMYWNASRVCAWFEEGRLARFGKMAKRKKLTGLQLLRMHVPEDLEEVES-DVAERLHAAEMIRALQQT
.  |  . ||.| |  ....  .. .. ...| .||..   |||.|.   ..  |.  .  |. ....
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
SAM_2 33651.AA SAM_2 1011-1048 21 0.020351 11.15 Pfam 1-41 (71) Show / Hide 
Range on Protein: 1011-1048
Range on HMM: 1-41/71
Sequence Identity: 21% (9 aa)

PMYWNASRVCAWFEEGRL-ARFGKMAKRKKLTG-LQL-LRM
. ||....||.|... .. ...  . .....||  .| ..|
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHM
Sam7 33651.AA sam7 1014-1048 18 0.02825 6.07 In-house 1-43 (70) Show / Hide 
Range on Protein: 1014-1048
Range on HMM: 1-43/70
Sequence Identity: 18% (8 aa)

WNASRVCAWFEEGRL---ARFGKMAKRKKL-----TGLQLLRM
|. . || | |. ..    .. .. .. .      .| .|..|
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHM
Sam7 33651.AA sam7 1086-1146 24 1.3e-11 39.18 In-house 1-70 (70) Show / Hide 
Range on Protein: 1086-1146
Range on HMM: 1-70/70
Sequence Identity: 24% (17 aa)

WTVSDVADWLDQVEC---GIVKKTFARKRI-----DGPALCRLSNAHMDDLGV-PAERRHDLLLRIQQLS
||..||..||. ...   .  ...| . .|     || .||...  .. ..|.     |. ..  |||. 
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM 33651.AA SAM 1083-1148 30 1.4e-11 45.75 SMART 1-67 (67) Show / Hide 
Range on Protein: 1083-1148
Range on HMM: 1-67/67
Sequence Identity: 30% (21 aa)

VASWTVSDVADWLDQVECGIVKKTFARKRIDGPALCRLS-NAHMDDLGV-PAERRHDLLLRIQQLSTQ
|  ||..||.|||.   .. .|..|.. .||| .| .|.  ... ..|. ..  |. .|  ||.. .|
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
SAM_2 33651.AA SAM_2 1083-1146 22 3.3e-10 37.86 Pfam 1-71 (71) Show / Hide 
Range on Protein: 1083-1146
Range on HMM: 1-71/71
Sequence Identity: 22% (16 aa)

VASWTVSDVADWLDQVEC-GIVKKTFARKRIDG-PAL-CRLSNAHM--D-DLGV-PAERRHDLLLRIQQLS
| .||..||..||... . .  |  | .. |.|  .|  ...  ..    ..|.  . .|. ..  ||.. 
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
SAM_1 33651.AA SAM_1 1084-1130 22 0.000536 17.16 Pfam 1-49 (66) Show / Hide 
Range on Protein: 1084-1130
Range on HMM: 1-49/66
Sequence Identity: 22% (11 aa)

ASWTVSDVADWLDQVECGIVKKTF-ARKRIDGPALCRLSNAHMDD-LGV
  |...||..||.   ..  ...| .. .||. .| ...   . . .||
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDLMKHMGV
Sam7 33651.AA sam7 1159-1220 32 4.2e-13 44.48 In-house 1-70 (70) Show / Hide 
Range on Protein: 1159-1220
Range on HMM: 1-70/70
Sequence Identity: 32% (23 aa)

WSFPEVKAWLEAEGF---GHLCPNLRRK------VTGDEFMHMDSHEDLLKLGIRDPSEQVELLEHIAELR
|.| .|  |||. |.   .. |.|.|.       ..||...||.  |||...|| .|  .  ...||  .|
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTE-EDLMEMGITRPGHRKKIWNHIQQMR
SAM 33651.AA SAM 1156-1222 29 2.1e-11 45.12 SMART 1-67 (67) Show / Hide 
Range on Protein: 1156-1222
Range on HMM: 1-67/67
Sequence Identity: 29% (20 aa)

ARSWSFPEVKAWLEAEGFGHLCPNLRR-KVTGDEFMHMDSHEDLLKLGIRDPSEQVELLEHIAELRRQ
.  |....| .|||. |... ..|.|. ...|... ...|||||...|| .|  .  .|  | ... |
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
SAM_2 33651.AA SAM_2 1156-1220 25 1.6e-10 38.98 Pfam 1-71 (71) Show / Hide 
Range on Protein: 1156-1220
Range on HMM: 1-71/71
Sequence Identity: 25% (18 aa)

ARSWSFPEVKAWLEAEGF-GHLCPNLRR-KVTG-DEF-MHMDSHEDL--L-KLGIRDPSEQVELLEHIAELR
  .|.|..| .||.. |. .. ..|.|. ..|| .   .||. |.||    ..|| ..  . ... .| ...
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMT-HDDLAMKNRMGITNVGHRKKIWNKIQRMK
SAM_1 33651.AA SAM_1 1157-1220 25 2.3e-07 29.1 Pfam 1-66 (66) Show / Hide 
Range on Protein: 1157-1220
Range on HMM: 1-66/66
Sequence Identity: 25% (17 aa)

RSWSFPEVKAWLEAEGFGHLCPNL--RRKVTGDEFMHMDSHEDLLK-LGIRDPSEQVELLEHIAELR
  |.|  |  |||. |... ...   . ....|....|.  |||.| .|.. |  .  ..  |  |.
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMT-WEDLMKHMGVTLPGHRKKIMYSIQMLK
Sam7 33651.AA sam7 1276-1336 22 3.2e-09 30.69 In-house 1-70 (70) Show / Hide 
Range on Protein: 1276-1336
Range on HMM: 1-70/70
Sequence Identity: 22% (16 aa)

WPCSQVVDWLYVQGC---GQYCLTFFEANV-----DGPALLAVDLERLSALGL-DEAGAGLVLKNIDVLS
|....|..||   |.   .||| .| ....     || .|. ...| | ..|  .   .   .. |. . 
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM_1 33651.AA SAM_1 1274-1319 31 9e-06 23.41 Pfam 1-48 (66) Show / Hide 
Range on Protein: 1274-1319
Range on HMM: 1-48/66
Sequence Identity: 31% (15 aa)

ALWPCSQVVDWLYVQGCGQYCLTFFEANV-DGPALLAVDLERLSA-LG
  |....| .||   |..||. .| .|.  |. .||  . | | . .|
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDLMKHMG
SAM 33651.AA SAM 1273-1338 29 9e-05 23.1 SMART 1-67 (67) Show / Hide 
Range on Protein: 1273-1338
Range on HMM: 1-67/67
Sequence Identity: 29% (20 aa)

AALWPCSQVVDWLYVQGCGQYCLTFFEANVDGPALLAVD-LERLSALGLDEAGAG-LVLKNIDVLSLE
.  |....| |||   |..||. .| ....|| .||. . .| |  .|   .|.    || |  .  .
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
SAM_2 33651.AA SAM_2 1273-1336 19 0.03212 10.47 Pfam 1-71 (71) Show / Hide 
Range on Protein: 1273-1336
Range on HMM: 1-71/71
Sequence Identity: 19% (14 aa)

AALWPCSQVVDWLYVQGC-GQYCLTFFEANVDG-PAL-LAVDLERL--S-ALGLDEAGA-GLVLKNIDVLS
   |  ..| .||   |. .||.  | .....|  .| . .... |    ..|   .|    ... |. . 
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
SAM_2 33651.AA SAM_2 1353-1417 26 7.8e-09 33.16 Pfam 1-71 (71) Show / Hide 
Range on Protein: 1353-1417
Range on HMM: 1-71/71
Sequence Identity: 26% (19 aa)

PWRMGVPDVELWLLSHGL-GKYNPDFQRRQITG-IDL-VLLTRAKL--I-TLGMENEEDQNTCLNAVERMV
..   ..||  || |.|. ..| . | . .|||  .|   .|  .|  .  .|..|  ...  .|...|| 
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
Sam7 33651.AA sam7 1356-1417 21 1.6e-08 28.27 In-house 1-70 (70) Show / Hide 
Range on Protein: 1356-1417
Range on HMM: 1-70/70
Sequence Identity: 21% (15 aa)

MGVPDVELWLLSHGL---GKYNPDFQRRQI-----TGIDLVLLTRAKLITLGMENEEDQNTCLNAVERMV
  . ||  || . |.   ..| . |..  |     .| .|  .|.  |  .|. .   ..  .|....| 
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM 33651.AA SAM 1353-1419 27 2.9e-08 34.72 SMART 1-67 (67) Show / Hide 
Range on Protein: 1353-1419
Range on HMM: 1-67/67
Sequence Identity: 27% (19 aa)

PWRMGVPDVELWLLSHGLGKYNPDFQRRQITGIDLVLLT-RAKLITLGMENEEDQNTCLNAVERMVEV
.    ..||  || | |...| . |.. .|.| .|..|| .. |  .|..|  ..   |.|.. | . 
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
SAM_1 33651.AA SAM_1 1357-1400 26 0.542761 6.52 Pfam 1-49 (66) Show / Hide 
Range on Protein: 1357-1400
Range on HMM: 1-49/66
Sequence Identity: 26% (13 aa)

GV---PDVELWLLSHGLGKYNPDF-QRRQITGIDLVLLTRAKLIT-LGM
..    ||  || | |...| . | ..  |.. .| ..|   |   .|.
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDLMKHMGV
Sam7 33651.AA sam7 1431-1492 21 7.4e-14 47.15 In-house 1-70 (70) Show / Hide 
Range on Protein: 1431-1492
Range on HMM: 1-70/70
Sequence Identity: 21% (15 aa)

WDVDQVCAWLRRQGL---ASLSTRFQSNGI-----DGAALLELTAVRCYQIGVHHAAHQTALFTSLDLLK
|....|| ||.  |.        .|...||     ||..|...|   . ..|..   |.  ...... ..
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM 33651.AA SAM 1428-1494 27 1.3e-12 49.14 SMART 1-67 (67) Show / Hide 
Range on Protein: 1428-1494
Range on HMM: 1-67/67
Sequence Identity: 27% (19 aa)

LSSWDVDQVCAWLRRQGLASLSTRFQSNGIDGAALLELT-AVRCYQIGVHHAAHQTALFTSLDLLKRA
 . |....||.||.  |..     |..|||||..||.||      ..|.. . |.  .. ..  .|  
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
SAM_2 33651.AA SAM_2 1428-1492 22 6.4e-09 33.47 Pfam 1-71 (71) Show / Hide 
Range on Protein: 1428-1492
Range on HMM: 1-71/71
Sequence Identity: 22% (16 aa)

LSSWDVDQVCAWLRRQGL-ASLSTRFQSNGIDG-AAL-LELTAVRC--Y-QIGVHHAAHQTALFTSLDLLK
 ..|....||.|||. |. .     | ..||.|  .| . .|.       ..|.. . |.  . .... .|
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
SAM_1 33651.AA SAM_1 1429-1492 27 2e-06 26.14 Pfam 1-66 (66) Show / Hide 
Range on Protein: 1429-1492
Range on HMM: 1-66/66
Sequence Identity: 27% (18 aa)

SSWDVDQVCAWLRRQGLASLSTRF-QSNGIDGAALLELTAVRCYQ-IGVHHAAHQTALFTSLDLLK
. |....|| ||.  |..     | ... ||. .||..|.    . .|| .. |.  .  |.  ||
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDLMKHMGVTLPGHRKKIMYSIQMLK
Sam7 33651.AA sam7 1507-1570 26 7.1e-05 15.3 In-house 1-70 (70) Show / Hide 
Range on Protein: 1507-1570
Range on HMM: 1-70/70
Sequence Identity: 26% (19 aa)

WTVEDVLQWLEANDF---VALMEHIGKLGV-----CGPLLLELTEEDLANIFESRIT-EDTARRLLDAIGRLT
||.||| .|||. ..       ... . |.      | .|...|||||.      ||    ..... .| .. 
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLME---MGITRPGHRKKIWNHIQQMR
SAM 33651.AA SAM 1504-1572 33 0.013178 10.96 SMART 1-67 (67) Show / Hide 
Range on Protein: 1504-1572
Range on HMM: 1-67/67
Sequence Identity: 33% (24 aa)

PQLWTVEDVLQWLEANDFVALMEHIGKLGVCGPLLLELT-EEDLANIFESRITEDTAR-RLLDAIGRLTKR
.  ||.||| .|||. ..   ...  | |. | .||.|| .||| ..    ||   .| ..| ||  . ..
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEM---GITNPGHRKKILKAIQKMKDQ
SAM_1 33651.AA SAM_1 1505-1546 32 0.014118 12.13 Pfam 1-43 (66) Show / Hide 
Range on Protein: 1505-1546
Range on HMM: 1-43/66
Sequence Identity: 32% (14 aa)

QLWTVEDVLQWLEANDFVALMEHI-GKLGVCGPLLLELTEEDL
. |..||| .|||. ..   ..|   .  . . .||..|.|||
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDL
SAM_2 33651.AA SAM_2 1504-1518 46 0.990995 5.36 Pfam 1-15 (71) Show / Hide 
Range on Protein: 1504-1518
Range on HMM: 1-15/71
Sequence Identity: 46% (7 aa)

PQLWTVEDVLQWLEA
.  ||.||| .||..
VHYWTFEDVCEWLRS
Sam7 33651.AA sam7 1597-1658 28 1.2e-15 53.46 In-house 1-70 (70) Show / Hide 
Range on Protein: 1597-1658
Range on HMM: 1-70/70
Sequence Identity: 28% (20 aa)

WSMNDVGQWLEGIAM---GHLRSVFLNNSI-----SGPSLQRLSPDDLTTMGILDGRARAILMTEIARLR
|. .||..|||.| |   .. .. |... |     .|  |.... .||  ||| ..  |  ....| ..|
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM 33651.AA SAM 1594-1660 32 2.8e-14 54.66 SMART 1-67 (67) Show / Hide 
Range on Protein: 1594-1660
Range on HMM: 1-67/67
Sequence Identity: 32% (22 aa)

VSHWSMNDVGQWLEGIAMGHLRSVFLNNSISGPSLQRLS-PDDLTTMGILDGRARAILMTEIARLRKS
|. |...||..|||.| |.. .. |. | |.|  | .|.  .||. ||| .  .|  .. .|  ....
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
SAM_1 33651.AA SAM_1 1595-1658 28 7.8e-14 51.98 Pfam 1-66 (66) Show / Hide 
Range on Protein: 1595-1658
Range on HMM: 1-66/66
Sequence Identity: 28% (19 aa)

SHWSMNDVGQWLEGIAMGHLRSVF-LNNSISGPSLQRLSPDDLTT-MGILDGRARAILMTEIARLR
..|. .||..||| | |.. .. |  .. |..  |......||   ||.     |  .| .| .|.
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDLMKHMGVTLPGHRKKIMYSIQMLK
SAM_2 33651.AA SAM_2 1594-1658 29 8.6e-14 50.17 Pfam 1-71 (71) Show / Hide 
Range on Protein: 1594-1658
Range on HMM: 1-71/71
Sequence Identity: 29% (21 aa)

VSHWSMNDVGQWLEGIAM-GHLRSVFLNNSISG-PSL-QRLSPDDL--T-TMGILDGRARAILMTEIARLR
|. |...||..||..| | .. .  |. . |.|   | .... |||  .  ||| .   |  ....| |..
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
SH2 33651.AA SH2 1737-1819 23 0.000516 8.45 SMART 1-87 (87) Show / Hide 
Range on Protein: 1737-1819
Range on HMM: 1-87/87
Sequence Identity: 23% (21 aa)

AGWARPDMQPHRAQQLLTG--ATPGHFLVHQAAN-SQMLQLSYVNEHGAVRSPQLSYDRPGQVTTRG--GHAFASFTDLLEHY-ANPEH
  |   ..  . |.||| .    .| ||| .  .  . . ||.  . | |.  ..  . .|..   .  .. | |  .|..||  ||  
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 33651.AA SH2 2190-2286 18 0.000333 10.48 SMART 1-87 (87) Show / Hide 
Range on Protein: 2190-2286
Range on HMM: 1-87/87
Sequence Identity: 18% (18 aa)

WTWCQVGLPAHQALQELDR--RPPGTFVVRTPEPEDEALPGGTDVVLVLTVLEEDGLQHVPINFSLQSGHAGLTLANDGDSTFSSIEALLVALLKGGAS
  |.   .. ..| | | .   |.|.|.||  |.        .   .||.|  ... .|  |. .      .  .. ... .|.|.  |.    .   .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES--------NPGDYVLSVRWKGKVKHYRIRRNDD---GKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 33651.AA SH2 2322-2412 24 0.000229 12.22 SMART 1-87 (87) Show / Hide 
Range on Protein: 2322-2412
Range on HMM: 1-87/87
Sequence Identity: 24% (23 aa)

FSWWQLGKPADEALQVLEG--QKTGYFVIRD-DPERTGHYILSYLFQSKVLDEPLSRATRSKLLNQGYHLDRDLNHIYPSLQLLVEDHTQHAHS
  |     . .|| | | .  .. | |..|| ..   |.|.||. ...||    . |         .|..| . .. .|||  ||. ..... .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWKGKVKHYRIRRNDD-----GKYYIDETWRRKFPSL-ELVNHYQHNPLG