Gene 31066 (M.brevicollis)
31066
Species: M.brevicollis
Alias: 31066
External Links:
Annotation:
Sequence
Protein domains of 31066.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| CH | 31066.AA | CH | 4-113 | 16 | 1.3e-09 | 39.19 | SMART | 1-100 (100) | Show / Hide |
Range on Protein: 4-113 Range on HMM: 1-100/100 Sequence Identity: 16% (20 aa) LWQHTADWLCKLGALSGEDPTFQKDATVYDLTVALQDGTVLCDAANALVP-GCIPIVNRHPQQQFLRIQNIHAFLGALRNTFK---MKEAHLFTADGLHN .. |. ... .| ... ...||.|||. .|...| ..|. .. .| ...||..|| ... .. . . .|... . QEETFLRWCNSHL-------------PVNNFSTDWKDGVVLCQLINKIRPQDSIDWWH-----RFHCMENINYFLNFCEKYGMFLGVCCVVNFDPEDIVD GGE----MPQVVQCLATW |.. ...|..|| . GNNNRKDILGVIWCLMQL |
|||||||||
| CH | 31066.AA | CH | 31-118 | 19 | 3e-06 | 26.07 | Pfam | 25-119 (119) | Show / Hide |
Range on Protein: 31-118 Range on HMM: 25-119/119 Sequence Identity: 19% (19 aa) VYDL-TVALQDGTVLCDAANALVPGC-IPIVNR-HP-QQ--QFLRIQNIHAFLGALRNTFKMKEAHLFTADGLHN--GGEMPQVVQCLATWANTPQ | .. . ..|| .|| .... || |. | . .| ...|| .| . .. ..... ||... . . .| ...|. .|.. . | V-NFFFTDWRDGVALCALIHKYCPGLLIDWKKVFPPRMRKMPFHCMENINYALDFCEKKLGCPCVNLFDPEDIVYMPDGNPKSVMTYLWQLMHHFQ |
|||||||||
| RhoGEF | 31066.AA | RhoGEF | 232-405 | 36 | 1.3e-46 | 161.79 | Pfam | 1-196 (196) | Show / Hide |
Range on Protein: 232-405 Range on HMM: 1-196/196 Sequence Identity: 36% (72 aa) VLDELFSTENSYIKVLQMLTGTYLPNL-----REAFSIIDIHLIFMNITEIMDAHNRFLADLSE--LMART---TGRM--AGTCL--LN-HVTSFRIYGE |. |...|| ||.. |.... |. | .. .| .|| || || ||.. |.||| || | |. . . | |. |. . |..|.| VIQEIIQTERSYVRDLNIIIEHYMKPLRNCANPPILSPDEIHTIFSNIEEIYEFHQRFLEDLEERDRMECWNPPDYQCQTIGDCFMFLKHMFPFFKMYSE YISMLPDAIDRLKVMRKKAP-FQAALQAAQK---ASGQIFP-LEDLLRVPMQRILKYPLMIKELLKSTPS-DHP-DLDKLRVANTAFQDLATYINE |.. | |.. || ||| | ||. |....| . . |...| |.||| .||| .||||| ||. ||| | ..| | |....|..||| YCNNYPKAMKLLKKCRKKNPKFQQFLKWCEKENDPCCRRLDLLQSFLIKPVQRIPRYPLLLKELLKHTPPCDHPKDYEDLQKALEAMKEVASHINE |
|||||||||
| RhoGEF | 31066.AA | RhoGEF | 232-405 | 30 | 1.5e-40 | 141.98 | SMART | 1-211 (211) | Show / Hide |
Range on Protein: 232-405 Range on HMM: 1-211/211 Sequence Identity: 30% (64 aa) VLDELFSTENSYIKVLQMLTGTYLPNLRE--------AFSIIDIHLIFM-NITEIMDAHNRFLADLSELMART----------------TGRMAGTCLLN |. ||. || .|.. |.... .|. ... .| ....|| || || . |.|||..| | .. . . . | |... VIQELMQTERNYVRDLHIIVQHYMKPMQKEEKCHKLPFLSPDEVNHIFGPNIEEIYEFHRRFLDELEERIEEWDCSMDWKSFRNFQIRDICDRIGDCFMK H---VTSFRIYGEYISMLPDAIDRL-KVM--RKKAPFQAALQAAQKASGQI------FPLEDLLRVPMQRILKYPLMIKELLKSTPSDHPDLDKLRVANT . |..|.||.. |.|. | | | .|. .||.... ... . . ..|||.| .|||||.|||| .||.|| ||.|||| ..| | WFHAEEMFKMYSEYCNNHPYALKHLKKWMCCKKNPRFQKFCKECESHPNCRSNSEHRLTLEDFLIKPMQRITKYPLLLKEILKHTPPDHPDYEDLQKALD AFQDLATYINE . .|.|...|| CMKDVAQHCNE |
|||||||||
| SH2 | 31066.AA | SH2 | 626-687 | 39 | 2.1e-24 | 73.47 | Pfam | 15-81 (81) | Show / Hide |
Range on Protein: 626-687 Range on HMM: 15-81/81 Sequence Identity: 39% (27 aa) LKD--LPDGTFLVRESTSRQGSYSLTVVFQN---EVKHIKILRDGT--QYRLTEHAEGFDTVQQLVAFF |. |||||||||| | .|.|.|.|.... .|||..| |... |. ..| |...|.|| .. LMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHK--FCSLQELVEHY |
|||||||||
| SH2 | 31066.AA | SH2 | 611-693 | 34 | 1.3e-20 | 75.75 | SMART | 1-87 (87) | Show / Hide |
Range on Protein: 611-693 Range on HMM: 1-87/87 Sequence Identity: 34% (30 aa) EAWFLPG-AASLSESELKD--LPDGTFLVRESTSRQGSYSLTVVFQNEVKHIKILRDG-TQYRLTE-HAEGFDTVQQLVAFFQRQNLG . |. . |. || |||.||||.| | |.|.|.| ....|||..| |.. .|...| . . |... .||...|. || QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG |
|||||||||
| SH3_1 | 31066.AA | SH3_1 | 731-774 | 35 | 1.7e-11 | 41.87 | Pfam | 1-44 (49) | Show / Hide |
Range on Protein: 731-774 Range on HMM: 1-44/49 Sequence Identity: 35% (16 aa) RALFSYKATADDEISFDKGTELVLLNVVEEDDGWWRGRLPD-GQV .||. |.|. .||.|| || .. ... ... ..||.||. . ||. VALYDYQAQQPDELSFKKGDIIHVIEKSDD-WDWWKGRCNNTGQE |
|||||||||
| SH3 | 31066.AA | SH3 | 728-783 | 33 | 5.2e-09 | 37.18 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 728-783 Range on HMM: 1-58/58 Sequence Identity: 33% (20 aa) GRARALFSYKATADDEISFDKGTELVLLNVVEEDDGWWRGRLP----DGQVSATARCCYM ...|||..|.|. .||.|| || . .|. . |||||.||. | . .. . PYVRALYDYQAQNPDELSFKKGDIITVLEKD--DDGWWKGRCNRTGQEGWFPSNYVEEID |
|||||||||
| SH3_2 | 31066.AA | SH3_2 | 729-774 | 21 | 0.000345 | 17.56 | Pfam | 1-55 (68) | Show / Hide |
Range on Protein: 729-774 Range on HMM: 1-55/68 Sequence Identity: 21% (12 aa) RARALFSYKA-TADDE-----ISFDKGTELVLL-NVVEEDDGWWRG-RL-PDGQV ..|....|.. | .| ..| || .... | ...|.||.. . .|.. YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRR |
|||||||||