Gene 2269 (M.brevicollis)

2269

Species: M.brevicollis
Alias: 2269
External Links:
Annotation:

Classification

Group: TK-assoc
Family: PTP

Sequence

Name Sequence Type Origin Length Description Download
2269.AA Protein None 6981 None Fasta, JSON

Protein domain

Protein domains of 2269.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
CA 2269.AA CA 471-561 17 7.9e-09 36.58 SMART 1-121 (121) Show / Hide 
Range on Protein: 471-561
Range on HMM: 1-121/121
Sequence Identity: 17% (23 aa)

ALNVSEDV----ANGT------IVYTSLSNLVNSSGTVQFQLEDTTRT----FAILGDDLILTQTLDRETI---------DSYLVRLEASQAGVDG----
   . .|      ||       ..|. ..         .|.....| |      ..  ....|..||||..         ..| .. .|. .|       
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDS

------------VDALIIEVSVLDVNDNAP
             .   . . |||||||.|
HPTRKFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 515-537 29 8.65031 1.96 Pfam 56-82 (102) Show / Hide 
Range on Protein: 515-537
Range on HMM: 56-82/102
Sequence Identity: 29% (8 aa)

D---LILTQTLDRETI-DSYLVRLEAS
|   . .|. ||||.. . | . ..|.
DNGIITTTKPLDREQQNGQYHLTVMAT
CA 2269.AA CA 585-660 21 5.5e-15 57.03 SMART 1-121 (121) Show / Hide 
Range on Protein: 585-660
Range on HMM: 1-121/121
Sequence Identity: 21% (26 aa)

LPATDADL-----HAA------LVYSLSSSSQFALDSLTAN-----------LTSLVVFDADPVAL-------SPISLQMTASDGT--------------
. |||.|       .       ..||...  .|..|. | .           .|..  .| .   .       .  .|. .|.||               
VTATDPDEGHNGPNGQPNDPEMVTYSIVG--WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKFQ

----FSSSAAVTVVILDVNDNAP
    .||.. ||. .||||||.|
QNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 568-653 23 0.000305 17.47 Pfam 1-102 (102) Show / Hide 
Range on Protein: 568-653
Range on HMM: 1-102/102
Sequence Identity: 23% (24 aa)

YYLFFNENSSVGTSLAMLPATDAD----LHAALVYSLSSSS-----QFALDSLTAN---LTSLVVFDADPVALSPISLQMTASDG-----TFSSSAAVTV
|   . ||..|||... . |||.|    ... ..||... .     .|..|. |     .|     |      .  .| . |.|.       || . ||.
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQ-NGQYHLTVMATDHDDGGPPRSSTTTVTI

VIL
 ..
TVC
CA 2269.AA CA 684-764 23 3.3e-19 71.06 SMART 1-121 (121) Show / Hide 
Range on Protein: 684-764
Range on HMM: 1-121/121
Sequence Identity: 23% (29 aa)

VQATDADRA--LVNRQ------LKYTLLNATDIVRVAASTG-----------AITLIGALDYESQ---------TSFVVAVQASDSAATP----------
|.|||.|      | |      ..|....     .. ..||            ||. ..||.|.|          .. . |||.|..  |          
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----QRTTVYFRLLVSDVNDNGP
     . .|. ..  | ||||| |
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 667-757 27 1.3e-17 63.99 Pfam 1-102 (102) Show / Hide 
Range on Protein: 667-757
Range on HMM: 1-102/102
Sequence Identity: 27% (28 aa)

YQVTVPESTATGTQLARVQATDAD-RALVNRQLKYTLLNAT----DIVRVAASTGA---ITLIGALDYESQ-TSFVVAVQASDS--AATPQRTTVYFRLL
|...|.| ...|| ...|.|||.|     | ...| .|.      .. |.   ||    ||.   ||.|.|   ... | |.|.  . .|...|.. .  
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VS
| 
VC
He_PIG 2269.AA He_PIG 719-743 23 17.500715 1.18 Pfam 36-61 (61) Show / Hide 
Range on Protein: 719-743
Range on HMM: 36-61/61
Sequence Identity: 23% (6 aa)

TLIGALDYESQT-SFVVAVQASDSAA
|. |  .. .|  .. . |.|.|.. 
TISGTPTTTVQPGTYTFTVTATDASG
CA 2269.AA CA 788-866 20 1.9e-14 55.25 SMART 1-121 (121) Show / Hide 
Range on Protein: 788-866
Range on HMM: 1-121/121
Sequence Identity: 20% (25 aa)

TSAADPDT----VGPR------PTYSSNNLPAFFSLNSQSG-----------ALVLSIAVDYETA--------AASYAFEIVATDADNG-----------
 .| |||.       .       ||| ..   .||.....|            .... . |.|.         ...| ....|||...            
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----LTATQSIQVQLLDVNDNAP
     |..| ......||||||.|
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 771-859 24 4.2e-10 37.87 Pfam 1-102 (102) Show / Hide 
Range on Protein: 771-859
Range on HMM: 1-102/102
Sequence Identity: 24% (25 aa)

ANFSFPESTTVGTTVFTTSAADPD---TVGPRPTYSSNNLPA----FFSLNSQSGA---LVLSIAVDYETAAASYAFEIVATDA-D--NGLTATQSIQVQ
 .||..| . |||.| |  | |||   .   |..||  . .      |......|    . .   .|.|. .  | . ..|||. |   ....| .. ..
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

LL
..
VC
He_PIG 2269.AA He_PIG 801-846 23 0.003117 14.32 Pfam 1-61 (61) Show / Hide 
Range on Protein: 801-846
Range on HMM: 1-61/61
Sequence Identity: 23% (15 aa)

TYSS-----------------NNLPAFFSLNSQSGALVLSIAVDYETAAASYAFEIVATDADN
||.                  | |||  ..|| .|..  .  ... ... .| | . |||| .
TYTATKPKDGSTTTYSTTPGGNGLPAGLTFNSTTGTISGT--PTTTVQPGTYTFTVTATDASG
CA 2269.AA CA 890-971 25 1e-23 86.0 SMART 1-121 (121) Show / Hide 
Range on Protein: 890-971
Range on HMM: 1-121/121
Sequence Identity: 25% (32 aa)

IEVRDADSG---ANGN------VTLSIDATFSDAVVVIHPTTG-----------VVSLTSSLDYEQD---------QEYFFRVLARDAGSPQ--------
. ..|.|.|    ||.      || ||          |.|.||           ....| .||.|.          ..| ..| |.|.|.|.        
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTR

-------QETIRDFRINVLDVNDNTP
       ...   ..|.||||||| |
KFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 873-964 28 8.8e-18 64.64 Pfam 1-102 (102) Show / Hide 
Range on Protein: 873-964
Range on HMM: 1-102/102
Sequence Identity: 28% (29 aa)

TEFDVLESASVETVIARIEVRDAD--SGANGNVTLSIDATFS--DAVVVIHPTTGV---VSLTSSLDYEQD-QEYFFRVLARDA--GSPQQETIRDFRIN
 .| | | |.| | .... ..|.|  .|.|.... ||  . .  .    |.| ||.   ...| .||.||  ..| . |.|.|.  |.| ...    .|.
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VL
|.
VC
CA 2269.AA CA 993-1067 18 2e-11 45.23 SMART 1-121 (121) Show / Hide 
Range on Protein: 993-1067
Range on HMM: 1-121/121
Sequence Identity: 18% (23 aa)

IDARDADLT--PAFRN------ISFTTNSPVVSIDSEG------------RVILEEALDYEAD---------TFYEVTVFLSDGR---------------
. |.|.|        .      .... ..   |||...             ... ..||.|.            |..||  .||                
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKFQQ

---FVSSMLLSLTVLDVNDNRP
   . |.  .  .|||||||.|
NPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 976-1060 26 0.000856 15.91 Pfam 1-102 (102) Show / Hide 
Range on Protein: 976-1060
Range on HMM: 1-102/102
Sequence Identity: 26% (27 aa)

LAISVWENATVGSVLAWIDARDAD--LTP---AFRNISFTTN--SPVVSIDS-EGR---VILEEALDYEAD-TFYEVTVFLSDG-----RFVSSMLLSLT
  .|| ||| ||. .. . |.|.|  |.|   .| .|. .    .   .||.  |.   . . . ||.|.    |..|| ..|.        |   .  |
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VL
|.
VC
CA 2269.AA CA 1091-1170 24 5e-27 97.02 SMART 1-121 (121) Show / Hide 
Range on Protein: 1091-1170
Range on HMM: 1-121/121
Sequence Identity: 24% (30 aa)

VTALDLDSG---VNAA------LRYTLASDESFLTIGSVSG-----------ILTLDSALDFESL---------SSFSVNVTVTDMGSPA----------
||| |.|.|    |.       ..|.. .   . .| . .|           ..|.  .||.|.          ......|..||.|.|           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----LSTTAILQVMVLDVNDNSP
     ||.|. ... ||||||| |
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 1074-1163 26 1.4e-21 77.85 Pfam 1-102 (102) Show / Hide 
Range on Protein: 1074-1163
Range on HMM: 1-102/102
Sequence Identity: 26% (27 aa)

SSITLAEDLVTGTSVLTVTALDLD--SGVNAALRYTLASDES----FLTIGSVSGI---LTLDSALDFESL-SSFSVNVTVTDM--GSPALSTTAILQVM
 .... |. ..||.|.|||| | |  .| |. ..| . ....      .| . .|    .|.   || |.  . ....| .||.  |.|..|.|. . . 
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VL
|.
VC
CA 2269.AA CA 1192-1269 27 2.8e-19 71.27 SMART 1-121 (121) Show / Hide 
Range on Protein: 1192-1269
Range on HMM: 1-121/121
Sequence Identity: 27% (34 aa)

SGATDADAG---DNGA------VTYALVNDFGGLFSLSGTS-------------LTHA-QLDAEVA---------TEYSVVVRATDGGTPA---------
  |||.|.|   .||       ||| .|.    .||.  ..             .| . .|| |            .|...|.|||||.|          
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

------LSSDLVLVISVQDLNDEAP
      |||   ..| |.| || .|
FQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 1177-1262 27 5.1e-14 51.53 Pfam 1-102 (102) Show / Hide 
Range on Protein: 1177-1262
Range on HMM: 1-102/102
Sequence Identity: 27% (28 aa)

LSETVDEN--TAGSIAFSGATDAD--AGDNGAVTYALVNDF---GGLFSLSG-TSL-----THAQLDAEVA-TEYSVVVRATDG--GTPALSSDLVLVIS
 . .| ||  .  ...  .|||.|   |.|. ..|.....    |. |..   |       | ..|| |    .|...|.|||.  |.|..||  ...|.
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VQ
|.
VC
He_PIG 2269.AA He_PIG 1219-1248 29 0.510656 6.56 Pfam 37-61 (61) Show / Hide 
Range on Protein: 1219-1248
Range on HMM: 37-61/61
Sequence Identity: 29% (9 aa)

LSGTSLTHAQLDAEVAT-EYSVVVRATDGGT
.|||       .. |.  .|.. |.|||...
ISGT------PTTTVQPGTYTFTVTATDASG
Cadherin 2269.AA Cadherin 1277-1305 33 7.430582 2.19 Pfam 1-30 (102) Show / Hide 
Range on Protein: 1277-1305
Range on HMM: 1-30/102
Sequence Identity: 33% (10 aa)

LQFSVREDDVFPTNLSTLTISDAD-VTASN
 .|||.|. . .| . |.|..|.| ... |
YHFSVCENAPVGTFVMTVTATDPDDPLGPN
Cadherin 2269.AA Cadherin 1351-1364 28 22.9967 0.48 Pfam 89-102 (102) Show / Hide 
Range on Protein: 1351-1364
Range on HMM: 89-102/102
Sequence Identity: 28% (4 aa)

PAMATTSPLTINIE
|.. .| ..||...
PPRSSTTTVTITVC
CA 2269.AA CA 1395-1481 23 4.5e-15 57.33 SMART 1-121 (121) Show / Hide 
Range on Protein: 1395-1481
Range on HMM: 1-121/121
Sequence Identity: 23% (29 aa)

VWVEDADLD---ENGA------ITFALLNATSFFSIAKGARVGNTTSA------TLYSQYRFDREAQ---------ATYLVALRASDGGADT--------
| . |.| .   .||       .|. ...   .|||   .. |. ...      ..... ..|||.|         ..| .  .|.|||           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSI--DPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTR

-------KSATVTITVQIGDLNDNPP
       .|.|.|.|... | |||||
KFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 1378-1472 27 3.7e-13 48.53 Pfam 1-102 (102) Show / Hide 
Range on Protein: 1378-1472
Range on HMM: 1-102/102
Sequence Identity: 27% (29 aa)

DTMTVLENQAVGTVVGQVWVEDAD--LDENGAITFALLNATS----FFSIAKGARVGNTTSATLYSQYRFDREAQ-ATYLVALRASDG-G---ADTKSAT
 ...| ||..||| |..| . |.|  |  |. |....|.  .     |.| .   .     . .. . . |||.|  .| . ..|.|. .   . .  .|
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDN----GIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTT

VTITVQ
|||||.
VTITVC
Cadherin 2269.AA Cadherin 1488-1574 29 7.3e-14 50.99 Pfam 1-99 (102) Show / Hide 
Range on Protein: 1488-1574
Range on HMM: 1-99/102
Sequence Identity: 29% (29 aa)

YSVSVSEALSVGTTVLQLTASDAD--VGENAAFFFERVSGSA----SFN-TTLAGA---IQVIAPLDYETQ-TFHTLTVAVLDE-SGSGALRTVQIYIV
|..||.|  .|||.|...||.|.|   | |.  |.  ..|.      |  ..  |    | . .|||.|.|   ..||| . |. .|. .....   ..
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTI
CA 2269.AA CA 1505-1581 22 1.3e-12 49.1 SMART 1-121 (121) Show / Hide 
Range on Protein: 1505-1581
Range on HMM: 1-121/121
Sequence Identity: 22% (28 aa)

LTASDADVG---ENAA------FFFERVSGSASFNTTLAG------------AIQVIAPLDYETQ---------TFHTLTVAVLDESG------------
.||.|.| |   .|.       . .. |.    |     .             | . .|||.|.|           .|||| . |  |            
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----SGALRTVQIYIVDENDNSP
       .  ||.| ..|.||| |
QQNPPLSSTCTVTIHVLDVNDNPP
He_PIG 2269.AA He_PIG 1486-1512 29 23.983376 0.7 Pfam 35-61 (61) Show / Hide 
Range on Protein: 1486-1512
Range on HMM: 35-61/61
Sequence Identity: 29% (8 aa)

GSYSVSVSEALSVGTTVLQLTASDADV
|  | ... . ..||.   .||.||  
GTISGTPTTTVQPGTYTFTVTATDASG
CA 2269.AA CA 1604-1693 30 4.3e-32 113.87 SMART 1-121 (121) Show / Hide 
Range on Protein: 1604-1693
Range on HMM: 1-121/121
Sequence Identity: 30% (41 aa)

VFATDADSG---MNAA------LTYSIVSVVPSVTGETPSSQLFAMAPTTG-----------VVTTTAPLDFEKV---------KAYNITVQATDAGVPP
| |||.|.|    |.       .|||||.             .|.. |.||           ..|||.|||.|.          . |..||||||.| ||
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-------------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPP

---------------RATTSVFTVELTDVNDNAP
               . .|. .|....|||||.|
PPDSHPTRKFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 1587-1686 34 6.6e-22 79.0 Pfam 1-102 (102) Show / Hide 
Range on Protein: 1587-1686
Range on HMM: 1-102/102
Sequence Identity: 34% (37 aa)

SKVVITEATSPGTSIEQVFATDAD--SGMNAALTYSIVSVVPSVTGETPSSQLFAMAPTTGV---VTTTAPLDFEKV-KAYNITVQATDA--GVPPRATT
  . . | ...||.. .| |||.|  .| |. ..|||..  |.       .. |.. | ||.   .|||.||| |.    |..|| |||.  | ||| .|
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPD------PGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSST

SVFTVELT
 . |....
TTVTITVC
He_PIG 2269.AA He_PIG 1660-1672 53 0.677376 6.13 Pfam 49-61 (61) Show / Hide 
Range on Protein: 1660-1672
Range on HMM: 49-61/61
Sequence Identity: 53% (7 aa)

AYNITVQATDAGV
.|..||.||||. 
TYTFTVTATDASG
CA 2269.AA CA 1719-1796 23 1.2e-24 89.1 SMART 1-121 (121) Show / Hide 
Range on Protein: 1719-1796
Range on HMM: 1-121/121
Sequence Identity: 23% (29 aa)

MPVTDADSG---LNAA------LSFTLSSPYFAINASTG-----------GVTLAAPIDYEQV---------QALALNVLVTDGGVPT------------
  .||.|.|    |.       ....... .|.|...||            .|...|.|.|.          .   |.| .|||| |             
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKFQQ

---RTLPVSLAITVLDVNDNAP
   .. .... |.|||||||.|
NPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 1701-1789 28 4.6e-13 48.2 Pfam 1-102 (102) Show / Hide 
Range on Protein: 1701-1789
Range on HMM: 1-102/102
Sequence Identity: 28% (29 aa)

LAYNVSEDSAVGLTLFAAMPVTDAD--SGLNAALSFTLSSPY------FAINASTGG---VTLAAPIDYEQV-QALALNVLVTDG--GVPTRTLPVSLAI
    |.|...|| |  . . .||.|  .|.|. ... ....       |.|.  ||    .|...|.|.||  .   |.|..||.  | | |. .... |
YHFSVCENAPVG-TFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTI

TVL
||.
TVC
CA 2269.AA CA 1818-1894 18 5.9e-12 46.96 SMART 1-121 (121) Show / Hide 
Range on Protein: 1818-1894
Range on HMM: 1-121/121
Sequence Identity: 18% (23 aa)

VSVSDADTG-----SN------FVFVVPPSVPVIIAGDG------------TVTLSEPLDREQV---------ASYDVLVTVYDQPAAPR----------
|...|.|.|     ..      ... . .  .  |  ..            ..|...|||||.          ..| . |.. |.   |.          
VTATDPDEGHNGPNGQPNDPEMVTYSIVG--WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKFQ

----NSAQFRLVVTVTDVNDNVP
     |..  ....|.||||| |
QNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 1844-1887 30 0.000635 16.36 Pfam 54-102 (102) Show / Hide 
Range on Protein: 1844-1887
Range on HMM: 54-102/102
Sequence Identity: 30% (15 aa)

DGT---VTLSEPLDREQV-ASYDVLVTVYDQ-PAAPRNSAQFRLVVTVT
.|.   .|. .||||||    | . | . |.  . |  |.  ....||.
TGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTITVC
Cadherin 2269.AA Cadherin 1801-1828 40 0.001386 15.18 Pfam 1-30 (102) Show / Hide 
Range on Protein: 1801-1828
Range on HMM: 1-30/102
Sequence Identity: 40% (12 aa)

ASFSVREDASVNAVLGTVSVSDAD--TGSN
 .|||.|.|.|.  ..|| ..|.|  .| |
YHFSVCENAPVGTFVMTVTATDPDDPLGPN
CA 2269.AA CA 1918-1993 19 6.2e-12 46.9 SMART 1-121 (121) Show / Hide 
Range on Protein: 1918-1993
Range on HMM: 1-121/121
Sequence Identity: 19% (24 aa)

YLATDPDVD-----NA------IVYNLVQDGVVATRNATG------------HLLLDPLDRETV---------SAFNLTLVAFNPDKPA-----------
  ||||| .             ..| .|.    .    ||              .. |||||.          . ..|| .| . . |            
VTATDPDEGHNGPNGQPNDPEMVTYSIVG--WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKFQ

----SQGRLVIAVTVTDINDNVP
     ..   . ..|.|.||| |
QNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 1901-1986 22 0.0002 18.11 Pfam 1-102 (102) Show / Hide 
Range on Protein: 1901-1986
Range on HMM: 1-102/102
Sequence Identity: 22% (23 aa)

LAVNVTESSNSITVLGPYLATDPD----VDNAIVYNLVQDGV-------VATRNAT-GHLLLD-PLDRETV-SAFNLTLVAFNP-D-KPASQGRLVIAVT
  . | | . . | .. . |||||        |.|.......       . ... . |.. .  |||||.  . ..||..| .  |  |.  .. .. .|
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VT
|.
VC
CA 2269.AA CA 2017-2097 20 1.5e-15 58.89 SMART 1-121 (121) Show / Hide 
Range on Protein: 2017-2097
Range on HMM: 1-121/121
Sequence Identity: 20% (26 aa)

FAPVDADEG---INAV------ITLSLANDYDGRFVLSPTY------------ELSLTQQLDREAFP--------NGIDLVITVQDAGTPS---------
.  .|.|||    |.       .| |. .     | . |.             ....|..||||.              |.....|.|.|.         
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

------LNSSASVHVNIIDVSDNAP
      | |...|.....|| ||.|
FQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 2001-2090 22 3.7e-09 34.6 Pfam 1-102 (102) Show / Hide 
Range on Protein: 2001-2090
Range on HMM: 1-102/102
Sequence Identity: 22% (23 aa)

TNINVIEE-NTTGVLRTFAPVDAD--EGINAVITLSLANDY---DGRFVLSP-TYE---LSLTQQLDREAFPNGIDLVITVQDA--GTPSLNSSASVHVN
 .. | |   .   . |.. .|.|  .| |. |. |. ..    .. | . | | .   ...|..||||. ..   |.. ..|.  |.|.. | ..|...
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

II
..
VC
CA 2269.AA CA 2122-2203 28 2.5e-20 74.77 SMART 1-121 (121) Show / Hide 
Range on Protein: 2122-2203
Range on HMM: 1-121/121
Sequence Identity: 28% (35 aa)

VTATSSDSG---ANAD------VAYSVSPTTRFRINASTG-----------VISTQPNMTFDRETI---------ASHTLTVSAVSGPE-----------
||||  |.|    |..      | ||...   |.|...||           .|.|.   ..|||..         ...|||| |. | .           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG--WFSIDPNTGTNYPSLVYCEIWITTT--KPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

---NKPLVAQVAVTVAIADINDNTP
   | || ... ||. . |.||| |
FQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 2104-2194 29 5.4e-15 54.91 Pfam 1-102 (102) Show / Hide 
Range on Protein: 2104-2194
Range on HMM: 1-102/102
Sequence Identity: 29% (31 aa)

YTFSLPEGTYATSSVVGQVTATSSD--SGANADVAYSVSPTT-----RFRINASTGV---ISTQPNMTFDRETI-ASHTLTVSAVSG---PENKPLVAQV
|.||..|..  . . |..|||| .|  .|.|. . || ...       |||.  ||.   |.|. .   |||..   ..|||.|. .   . ..  ...|
YHFSVCENAP-VGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKP--LDREQQNGQYHLTVMATDHDDGGPPRSSTTTV

AVTVA
 .|| 
TITVC
CA 2269.AA CA 2227-2316 25 3.6e-16 60.97 SMART 1-121 (121) Show / Hide 
Range on Protein: 2227-2316
Range on HMM: 1-121/121
Sequence Identity: 25% (34 aa)

FEATDADAG---VNAA------LTWSLQDTNNGRFSINENG------------ELKLERAFDFEAQ---------PYHQLTVVTMAVLRFDVLVTDTGEP
. |||.|.|    |.       .| |. .     |||..|.            .... ...|.|.|         | ..|||.          .|| |.|
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQ----------ATDGGGP

P---------------LSNSTSIMITVSDVNDNAP
|               || .... |.| |||||.|
PPPDSHPTRKFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 2210-2279 27 5.3e-12 44.5 Pfam 1-80 (102) Show / Hide 
Range on Protein: 2210-2279
Range on HMM: 1-80/102
Sequence Identity: 27% (22 aa)

ASLTLSEATAVGTTLHTFEATDAD--AGVNAALTWSLQDTN---NGRFSINE-NGE---LKLERAFDFEAQ-PYHQLTVV
 . ...| ..|||...|. |||.|   | |. .. |.  .|   .. |.|.. .|.   ... .  | |.| . . |||.
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVM
Cadherin 2269.AA Cadherin 2288-2309 45 0.022711 10.95 Pfam 79-102 (102) Show / Hide 
Range on Protein: 2288-2309
Range on HMM: 79-102/102
Sequence Identity: 45% (11 aa)

VLVTDT--GEPPLSNSTSIMITVS
|..||   |.||.|. |.. ||| 
VMATDHDDGGPPRSSTTTVTITVC
CA 2269.AA CA 2340-2419 27 1.5e-23 85.5 SMART 1-121 (121) Show / Hide 
Range on Protein: 2340-2419
Range on HMM: 1-121/121
Sequence Identity: 27% (34 aa)

LVATDADSG---INAA------VTLSVDAVSAERFHIDNDG------------YLRLSQRLDYEVR---------RAYNVTITATDGGFPA---------
..|||.|.|    |.       || |.       |.|| ..             ......||.| .           |..|..||||| |          
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

------LSSTALVRVHVTDVDDNAA
      ||||. |..||.||.||. 
FQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 2323-2412 28 1.1e-16 60.77 Pfam 1-102 (102) Show / Hide 
Range on Protein: 2323-2412
Range on HMM: 1-102/102
Sequence Identity: 28% (29 aa)

ISIGVAEDEAIGFALVQLVATDAD--SGINAAVTLSVDAVS---AERFHIDN-DGY---LRLSQRLDYEVR-RAYNVTITATDG--GFPALSSTALVRVH
 .. | |....|  . .. |||.|  .| |. .. |    .   .  |.||  .|    ... ..||.| . . |..|. |||.  | |..|||. |...
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VT
|.
VC
He_PIG 2269.AA He_PIG 2386-2398 46 0.471939 6.68 Pfam 49-61 (61) Show / Hide 
Range on Protein: 2386-2398
Range on HMM: 49-61/61
Sequence Identity: 46% (6 aa)

AYNVTITATDGGF
.|..|.||||.. 
TYTFTVTATDASG
CA 2269.AA CA 2442-2523 23 2.6e-16 61.45 SMART 1-121 (121) Show / Hide 
Range on Protein: 2442-2523
Range on HMM: 1-121/121
Sequence Identity: 23% (29 aa)

LHFTDADTG---INAQ------GTWSITAQTSAGQFGINASSG-----------RLVLLKALDFEML---------QEHEVSVQVTNQATGL--------
.. ||.|.|    |.|       | ||.      .| |....|            ....|.||.|           ..... ||.|....          
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTR

-------ASSVFVVEVDVTDVNDNAP
        ||   | . |.|||||.|
KFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 2425-2516 24 8.6e-14 50.74 Pfam 1-102 (102) Show / Hide 
Range on Protein: 2425-2516
Range on HMM: 1-102/102
Sequence Identity: 24% (25 aa)

GVAIMAEDAPVQATVAILHFTDAD--TGINAQGTWSITAQTS--AGQFGINASSGR---LVLLKALDFEML-QEHEVSVQVTNQ--ATGLASSVFVVEVD
 .. . |.|||. .|. .. ||.|  .| |.. . ||. . .  ...| |.  .|.   . . | || |   ......| .|..  ..   ||. .| . 
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VT
|.
VC
CA 2269.AA CA 2546-2626 22 1.1e-15 59.32 SMART 1-121 (121) Show / Hide 
Range on Protein: 2546-2626
Range on HMM: 1-121/121
Sequence Identity: 22% (27 aa)

ITATDADSL---GLSN------ASFVLNSSAFTVDSEG------------VVRTAMALDADNASS-------QYFSLSVIITDHQYPGPL----------
.||||.|.      ..       .. ...  |..|...            ...|. .|| .. .        . ..| |. ||.  | |           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKFQQ

---SSVPCPVEITVVDVNDNAP
    | .|.| |.|.|||||.|
NPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 2530-2617 23 4e-10 37.95 Pfam 1-102 (102) Show / Hide 
Range on Protein: 2530-2617
Range on HMM: 1-102/102
Sequence Identity: 23% (24 aa)

YAFSIPENVA-NGVVGVITATDAD--SLGLSNASFVLNSSA------FTVDS-EGV---VRTAMALDADNASSQYFSLSVIITDH--QYPGPLSSVPCPV
| ||..||.. .  |...||||.|  .   ..... . .        |..|.  |.   ..|.. ||     .. ..|.|. |||    |.. | ... .
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQ-NGQYHLTVMATDHDDGGPPRSSTTTVTI

EIT
...
TVC
CA 2269.AA CA 2649-2724 23 3e-17 64.57 SMART 1-121 (121) Show / Hide 
Range on Protein: 2649-2724
Range on HMM: 1-121/121
Sequence Identity: 23% (29 aa)

LIFTDADSG---NNGV------VNVQLNNSHFAVSNNQ-------------LVLQAALDYEIV---------TSLAVAVQATDEGSPA------------
.  ||.|.|   .||       |  .... .|..  |              ......||.|            .  . ||||| |.|             
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKFQQ

---QSTTVVVLVTVTDVNDNAP
   .|.|. | ..|.|||||.|
NPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 2632-2717 24 2.4e-09 35.24 Pfam 1-102 (102) Show / Hide 
Range on Protein: 2632-2717
Range on HMM: 1-102/102
Sequence Identity: 24% (25 aa)

LSFVVAESAETGAVLGPLIFTDAD--SGNNGVVNVQLNNSH------FAVSN--NQ---LVLQAALDYEIV-TSLAVAVQATDE--GSPAQSTTVVVLVT
 .| | | | .|  .. .  ||.|  .| |. .   . . .      |..    ..   . ... ||.|       . | |||.  |.|..|.|..| .|
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VT
|.
VC
CA 2269.AA CA 2747-2836 13 1.3e-09 39.23 SMART 1-121 (121) Show / Hide 
Range on Protein: 2747-2836
Range on HMM: 1-121/121
Sequence Identity: 13% (17 aa)

LVVMDADNE---PYAA------SHIFLNDSNTQCEQYLTVNSTSG-----------AVALVAPLDYEVI---------QELSCTVAVVNILPLVGSA---
... |.| .   | .        .  ...       . ......|            . ...|||.| .         .. . || ...  .  ...   
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHP

------AAEPWATTLVRVSVVDLDDNAP
        .  .|. |.. |.| .||.|
TRKFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 2731-2797 18 2e-06 25.22 Pfam 1-74 (102) Show / Hide 
Range on Protein: 2731-2797
Range on HMM: 1-74/102
Sequence Identity: 18% (14 aa)

YTATINENVA-SAEVATLVVMDADNEPYAASHIFLNDSNTQC--EQYLTVNSTSGA---VALVAPLDYEVI-QE
|.... ||..   .|.|. . |.| .  . . || . ...    ..  .... .|    . ...|||.| . ..
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQ
CA 2269.AA CA 2860-2940 15 2e-05 24.83 SMART 1-121 (121) Show / Hide 
Range on Protein: 2860-2940
Range on HMM: 1-121/121
Sequence Identity: 15% (19 aa)

FTGADADV---FQSPA------FSFVLALNTGAAPVTLAPNG------------TLYTSGDVDHEQL---------TEAPLIIRIQDDNNPL--------
.|  |.|     ..        ... .       . .. ||.            ...|..  |.|.           .  |... .| ..|         
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTR

-------YFADANVTLLIEDVNDNAP
         . . ||  ..|||||.|
KFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 2843-2866 41 0.012445 11.86 Pfam 1-24 (102) Show / Hide 
Range on Protein: 2843-2866
Range on HMM: 1-24/102
Sequence Identity: 41% (10 aa)

DTVTVPENVPRGTIVHVFTGADAD
 ...|.||.|.|| |...|  |.|
YHFSVCENAPVGTFVMTVTATDPD
CA 2269.AA CA 2963-3042 26 1.4e-28 102.24 SMART 1-121 (121) Show / Hide 
Range on Protein: 2963-3042
Range on HMM: 1-121/121
Sequence Identity: 26% (33 aa)

LNVTDADAG---ANSQ------ITYSILDSGSRLGINSTTG-----------ELRVLRRLNREST---------DALVIIVTATDGGAPP----------
...||.|.|    |.|      .||||..      |...||           .......|.||..         .   ..|.||||| ||          
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----RSTSQTITIQLTDINDNVP
     .|.. |.||...|.||| |
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 2946-3035 32 4.4e-21 76.12 Pfam 1-102 (102) Show / Hide 
Range on Protein: 2946-3035
Range on HMM: 1-102/102
Sequence Identity: 32% (33 aa)

NTLDVLEELSVGTTLSLLNVTDAD--AGANSQITYSILDSGS----RLGINSTTGE---LRVLRRLNREST-DALVIIVTATDG--GAPPRSTSQTITIQ
 .  | |  .|||..  ...||.|   |.|..|.||||  ..       |.. ||.   ... ..|.||.. .  ...| |||.  | ||||.  |.||.
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

LT
..
VC
CA 2269.AA CA 3066-3148 16 1.3e-09 39.13 SMART 1-121 (121) Show / Hide 
Range on Protein: 3066-3148
Range on HMM: 1-121/121
Sequence Identity: 16% (21 aa)

VEAVDADIN---DNAA------IEYLLFGAAGSYFNLNSTTG-----------TLAVQQSLLPLVG---------TTVTLEIMARHPIVTSSR-------
| |.|.|     .|.       ..| . |    .| ....||           .. ....|    .          . ||.. |.     . .       
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

------SARNATVVIQILNENENAP
         ..||.|..| .|.|.|
FQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 3049-3106 30 2.3e-07 28.37 Pfam 1-66 (102) Show / Hide 
Range on Protein: 3049-3106
Range on HMM: 1-66/102
Sequence Identity: 30% (20 aa)

YYEQVGELTPVNTTVLQVEAVDAD--INDNAAIEYLLFGAA---GSYFNLNSTTGT---LAVQQSL
|  .| | .||.|.|..| |.|.|    .|. | | . |     |  | ... ||.   . ....|
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPL
CA 2269.AA CA 3171-3250 27 8.3e-27 96.3 SMART 1-121 (121) Show / Hide 
Range on Protein: 3171-3250
Range on HMM: 1-121/121
Sequence Identity: 27% (34 aa)

MVATDADEG---ANGE------VRYSLTQGGSFVSIDAITG-----------VLTLRSGLDYETR---------QRVEVTVVARDQGAIF----------
 .|||.|||    ||.      |.||...   . |||. ||           ..|..  ||.|..         .. ..||.|.|.|             
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----QSSSVTFALIIVDVNDNGP
     .||..|.  ...||||| |
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 3154-3244 31 3.6e-22 79.92 Pfam 1-102 (102) Show / Hide 
Range on Protein: 3154-3244
Range on HMM: 1-102/102
Sequence Identity: 31% (32 aa)

ADISVLENVTTGTVIGQMVATDAD--EGANGEVRYSLTQGGS----FVSIDAITGV---LTLRSGLDYETR-QRVEVTVVARDQ-GAIFQSSSVTFALII
  .|| ||. .|| .... |||.|  .|.|. ..||...|..      .||  ||.   .|..  ||.|.. .....||.|.|. ..    ||.|   | 
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VD
| 
VC
CA 2269.AA CA 3272-3347 24 9.4e-14 52.94 SMART 1-121 (121) Show / Hide 
Range on Protein: 3272-3347
Range on HMM: 1-121/121
Sequence Identity: 24% (30 aa)

LQVTDADS-----VPD------FSLAIVDDITGVFAILPNA------------TITMSDSLDREVV---------ATVVFRAVATDSLG-----------
...||.|.       .      ..  ||.     |.| ||             .|| . .||||           ..  .. .|||. |           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

------RTSQVTVTVTVLDENDNAP
      ..|..|||..|||.|||.|
FQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 3257-3340 28 2.5e-07 28.22 Pfam 1-102 (102) Show / Hide 
Range on Protein: 3257-3340
Range on HMM: 1-102/102
Sequence Identity: 28% (29 aa)

ATFSVLENTR--ATFMGLQVTDAD----SVPDFSLAIVDDI---TGVFAILP-NAT---ITMSDSLDREVV-ATVVFRAVATDS-L---GRTSQVTVTVT
 .||| ||..   . | ...||.|         . .|. .     . |.| | . .   ||   .||||    ....  .|||.     .|.| .|||.|
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VL
|.
VC
CA 2269.AA CA 3370-3449 34 7.9e-33 116.3 SMART 1-121 (121) Show / Hide 
Range on Protein: 3370-3449
Range on HMM: 1-121/121
Sequence Identity: 34% (43 aa)

VTATDADSG---VNGQ------LTYSILSPTYGFTVDASTG-----------LVTGTVPLDFETR---------PHLTLTIVATDGGSPA----------
|||||.|.|    |||      .||||..    |..|..||            .| | |||.|..         |. |||..|||||.|           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----LSSSVLVNVQVQDTNDHSP
     |||.. |...|.| ||. |
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 3354-3442 34 2.1e-19 70.26 Pfam 1-102 (102) Show / Hide 
Range on Protein: 3354-3442
Range on HMM: 1-102/102
Sequence Identity: 34% (35 aa)

VNSTVREG-DTLPSLGYVTATDAD--SGVNGQLTYSILSPTY----GFTVDASTGL---VTGTVPLDFETR-PHLTLTIVATDG--GSPALSSSVLVNVQ
 . .|.|.  . .... |||||.|  .| |....||||..       |..|  ||    .| | ||| |.. .  .||..|||.  |.|..|| . |...
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VQ
|.
VC
He_PIG 2269.AA He_PIG 3395-3428 31 12.438296 1.7 Pfam 29-61 (61) Show / Hide 
Range on Protein: 3395-3428
Range on HMM: 29-61/61
Sequence Identity: 31% (11 aa)

TVDASTGLVTGTVPLDFETRP-HLTLTIVATDGGS
| ...||...||   .  . |   | |. |||.. 
TFNSTTGTISGT--PTTTVQPGTYTFTVTATDASG
CA 2269.AA CA 3473-3549 24 7.2e-21 76.57 SMART 1-121 (121) Show / Hide 
Range on Protein: 3473-3549
Range on HMM: 1-121/121
Sequence Identity: 24% (31 aa)

VVATDLDA-----NSI------LTYQLDAIGAALFNIDASSG-----------EIFTDAPLDYEER---------QQVIMVVTAYDEDS-----------
|.|||.|.     |.       .||..      .| ||...|           .|.| .|||.||.         .|  ..|.| | ..           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

------RSDSITVVLNIRDLNDNVP
      .|.. ||. .. | ||| |
FQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 3456-3542 29 7.4e-15 54.45 Pfam 1-102 (102) Show / Hide 
Range on Protein: 3456-3542
Range on HMM: 1-102/102
Sequence Identity: 29% (30 aa)

ITVTIDENVASDTLVVQVVATDLD----ANSILTYQLDAIG---AALFNIDASSGE---IFTDAPLDYEER-QQVIMVVTAYDE-D---SRSDSITVVLN
 .... ||... | | .| ||| |    .|. ..| .   .   .  | ||  .|.   |.| .|||.|.. .|.  .| | |. |   .||.  ||. .
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

IR
. 
VC
He_PIG 2269.AA He_PIG 3456-3480 32 3.78806 3.51 Pfam 37-61 (61) Show / Hide 
Range on Protein: 3456-3480
Range on HMM: 37-61/61
Sequence Identity: 32% (8 aa)

ITVTIDENVASDTLVVQVVATDLDA
|. |.. .|.  |  . | |||   
ISGTPTTTVQPGTYTFTVTATDASG
CA 2269.AA CA 3573-3652 25 2.3e-19 71.59 SMART 1-121 (121) Show / Hide 
Range on Protein: 3573-3652
Range on HMM: 1-121/121
Sequence Identity: 25% (32 aa)

VSATDADSG-MYGTAG------LQYSIVPSSGSHLFYLVGN-------------YLYLRDNVDREVY---------PILNIMVQARDGGN----------
|.|||.|.| .   .       . ||||.     .| .  |              ....   |||           |  .. |||.|||.          
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTR

-------LTATASVTVSMIDLNDNPP
       |..|..||.  .| |||||
KFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 3556-3645 23 7.2e-08 30.11 Pfam 1-102 (102) Show / Hide 
Range on Protein: 3556-3645
Range on HMM: 1-102/102
Sequence Identity: 23% (24 aa)

YSTTVVETLQSDYLVAVVSATDAD--SGMYGTAGLQYSIVPSSG--SHLFYLVG--NY---LYLRDNVDREVY-PILNIMVQARDG-G---NLTATASVT
|. .| |. ..   |..| |||.|  .|    ... |||.. .   .| | .    .    .... ..||| . .. .. | |.|. .   ....|..||
YHFSVCENAPVGTFVMTVTATDPDDPLGP--NWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVT

VSMI
.. .
ITVC
CA 2269.AA CA 3676-3758 27 2.5e-29 104.67 SMART 1-121 (121) Show / Hide 
Range on Protein: 3676-3758
Range on HMM: 1-121/121
Sequence Identity: 27% (34 aa)

ANASDPDEG---VNAL------IRYEMTGADAGLFAINTSTG-----------AITTAAVFDREAR---------EHYQVIVTARDAGNLA---------
 .|.|||||    |.       ..|...|    .|.|...||            |||.. .|||..         ..|...|.|.|.|.           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

----SVFFDTATVEITILDENDNAP
      . .|.|| |..||.|||.|
FQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 3659-3751 33 2.4e-22 80.54 Pfam 1-102 (102) Show / Hide 
Range on Protein: 3659-3751
Range on HMM: 1-102/102
Sequence Identity: 33% (35 aa)

ISLGIMENRPVGSFVGLANASDPD--EGVNALIRYEMTGAD---AGLFAINTSTGA---ITTAAVFDREAR-EHYQVIVTARDAGNLAS---VFFDTATV
 .  ..|| |||.||.  .|.|||  .| |. |.| ..| .   .. |.|.. ||    |||..  |||.. . | ..| |.|..   .     ..|.||
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHD---DGGPPRSSTTTV

EITIL
 ||..
TITVC
He_PIG 2269.AA He_PIG 3724-3735 50 11.957711 1.76 Pfam 50-61 (61) Show / Hide 
Range on Protein: 3724-3735
Range on HMM: 50-61/61
Sequence Identity: 50% (6 aa)

YQVIVTARDAGN
|.. ||| ||..
YTFTVTATDASG
CA 2269.AA CA 3782-3867 20 6.7e-17 63.38 SMART 1-121 (121) Show / Hide 
Range on Protein: 3782-3867
Range on HMM: 1-121/121
Sequence Identity: 20% (27 aa)

VVASDRDTG---ANAA------LRFELWNCAPATLMTCPFGFSGQQ-------------LLLIAPVDRETI---------DRYNLTVAVLDAAADAGP--
|.|.|.|.|    |.       ..... .         .|    .              . . .| |||..         ..|.||| . |..   .|  
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDS

-----------LNDTASVTVVIGDVNDNSP
           | .|..||. . ||||| |
HPTRKFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 3821-3860 33 5e-06 23.56 Pfam 62-102 (102) Show / Hide 
Range on Protein: 3821-3860
Range on HMM: 62-102/102
Sequence Identity: 33% (14 aa)

LIAPVDRETI-DRYNLTVAVLDAAAD-AGPLNDTASVTVVIG
. .|.|||.. ..|.||| . |.. |   |. .|..||. . 
TTKPLDREQQNGQYHLTVMATDHD-DGGPPRSSTTTVTITVC
Cadherin 2269.AA Cadherin 3765-3799 32 2.5e-05 21.28 Pfam 1-37 (102) Show / Hide 
Range on Protein: 3765-3799
Range on HMM: 1-37/102
Sequence Identity: 32% (12 aa)

TAFTVREDAAVNTTLFGVVASDRD--TGANAALRFEL
  |.|.|.|.|.|..  | |.|.|  .|.|. ... .
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSI
CA 2269.AA CA 3890-3965 21 4.3e-16 60.71 SMART 1-121 (121) Show / Hide 
Range on Protein: 3890-3965
Range on HMM: 1-121/121
Sequence Identity: 21% (27 aa)

VAATDADLG---INAL------IRYESANASIASVGSDG------------TVYLVGHLDYEQA---------VEVSFYVWAFDSGN-------------
| |||.| |    |.       ..|.  .    |. ...            .......||.|.           . .. | | |.|.             
VTATDPDEGHNGPNGQPNDPEMVTYSIVG--WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKFQ

----LSGSTLVHIMVQDVNDNAP
    ||... |.| |.|||||.|
QNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 3874-3958 28 1.6e-14 53.25 Pfam 1-102 (102) Show / Hide 
Range on Protein: 3874-3958
Range on HMM: 1-102/102
Sequence Identity: 28% (29 aa)

YNFSVAENTA-PGVIGNVAATDAD--LGINALIRYESANAS-----IASVGS-DGT---VYLVGHLDYEQA-VEVSFYVWAFDS-G---NLSGSTLVHIM
|.||| ||.. .  ...|.|||.|  || |. |.|   . .     . .. . .|.   .... .||.||   .....| | |. .   ..|. | |.| 
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VQ
|.
VC
CA 2269.AA CA 3988-4069 23 3.9e-19 70.81 SMART 1-121 (121) Show / Hide 
Range on Protein: 3988-4069
Range on HMM: 1-121/121
Sequence Identity: 23% (29 aa)

VVVTDADSG---LNQQ------FDLSVTGEGAEYVVIERENA---------TVRISVL-AIDREEY---------SALNVSLLATDQGTPS---------
|..||.|.|    | |      .  |..|    .  |....           . |... ..||||          .  ..   |||.|.|.         
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

------QMSSLPISITVTDVNDNAP
      . |. .. |.|.|||||.|
FQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 3972-4062 23 3.4e-11 41.7 Pfam 1-102 (102) Show / Hide 
Range on Protein: 3972-4062
Range on HMM: 1-102/102
Sequence Identity: 23% (24 aa)

IDIVLPENEN-RSSLASVVVTDAD--SGLNQQFDLSVTGEG---AEYVVIERENAT-VRISVL-AIDREEY-SALNVSLLATDQ--GTPSQMSSLPISIT
  . ..||.   .....| .||.|  .|.|..   | .| .   .    |.... . ..|..   .|||.. .  .....|||.  |.|.. |  .. ||
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VT
|.
VC
He_PIG 2269.AA He_PIG 4046-4066 25 30.375484 0.34 Pfam 38-61 (61) Show / Hide 
Range on Protein: 4046-4066
Range on HMM: 38-61/61
Sequence Identity: 25% (6 aa)

QGTPSQM---SSLPISITVTDVND
.|||..     .  . .|.|| . 
SGTPTTTVQPGTYTFTVTATDASG
CA 2269.AA CA 4092-4174 27 2.9e-23 84.54 SMART 1-121 (121) Show / Hide 
Range on Protein: 4092-4174
Range on HMM: 1-121/121
Sequence Identity: 27% (35 aa)

VPFTDADAG---ANGL------LQFYLFDAATVGSNFLLQPLTG-----------EIVTSRIFDREVQ---------GRYEFRVIAQDSGTPS-------
|  ||.|.|    ||       . . . .       | . | ||           .|.|.. .||| |          .|...|.|.|.|.|.       
VTATDPDEGHNGPNGQPNDPEMVTYSIVG------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPT

--------LSSTMNVTIIIGDLNDNRP
        ||||  |||.. | |||.|
RKFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 4075-4167 37 1.8e-20 73.98 Pfam 1-102 (102) Show / Hide 
Range on Protein: 4075-4167
Range on HMM: 1-102/102
Sequence Identity: 37% (39 aa)

FEATVLENQPAGTIVARVPFTDAD--AGANGLLQFYLFDAATV--GSNFLLQPLTGE---IVTSRIFDREVQ-GRYEFRVIAQDS--GTPSLSSTMNVTI
....| ||.| || |..|  ||.|   |.|. . || .    .  | .| ..| ||.   | | .  ||| | |.|.. |.|.|.  |.|..|||  |||
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRI-FYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTI

IIG
 . 
TVC
He_PIG 2269.AA He_PIG 4138-4153 47 1.550129 4.87 Pfam 45-61 (61) Show / Hide 
Range on Protein: 4138-4153
Range on HMM: 45-61/61
Sequence Identity: 47% (8 aa)

VQ-GRYEFRVIAQDSGT
|| | | |.| | |...
VQPGTYTFTVTATDASG
CA 2269.AA CA 4198-4277 20 5.6e-12 47.04 SMART 1-121 (121) Show / Hide 
Range on Protein: 4198-4277
Range on HMM: 1-121/121
Sequence Identity: 20% (25 aa)

LNATDADIG---VNAL------LNFTLLSSDWADLFVDAGTG-----------AIFL--SADYETQ---------TVITGTVKVENVNT-----------
..|||.| |    |.       . .....       .|. ||            |..  . |.|.|          . | ||.. . ..           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

---TVSTYDVATFTINILDVNDVAP
   . .  . .|.||..||||| .|
FQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 4181-4270 20 0.001306 15.27 Pfam 1-102 (102) Show / Hide 
Range on Protein: 4181-4270
Range on HMM: 1-102/102
Sequence Identity: 20% (21 aa)

FTAAVPEDINATVPALVLNATDAD--IGVNALLNFTLLSSD---WADLFVDAGTGA---IFLS--ADYETQ-TVITGTVKVENV-NTTVSTYDVATFTIN
... |.|.     . ....|||.|   | |. . . .|. .        .|  ||    |..    |.|.|    . ||.. .    . . ....| ||.
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

IL
..
VC
CA 2269.AA CA 4300-4376 29 1.7e-22 81.95 SMART 1-121 (121) Show / Hide 
Range on Protein: 4300-4376
Range on HMM: 1-121/121
Sequence Identity: 29% (36 aa)

VTGTDPDTG---LGGV------ITYSTNSSFFAINATTG-----------VVTTIPNAPLDREAA---------TVVELVIIATDGV-------------
|| ||||.|     |       .||| .. .|.|...||           ..||   .|||||.           . .|...||||              
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-WFSIDPNTGTNYPSLVYCEIWITTT--KPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----HNTSATIFVTVLDRNDNPP
     . ...|. ..||| |||||
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 4283-4369 31 1.1e-07 29.49 Pfam 1-102 (102) Show / Hide 
Range on Protein: 4283-4369
Range on HMM: 1-102/102
Sequence Identity: 31% (33 aa)

TNVSVYENTLEAVILGSVTGTDPD--TGLGGVITYS---TN---SSFFAINATTGV---VTTIPNAPLDREAA-TVVELVIIATDG-----VHNTSATIF
 ..|| ||.     ...|| ||||  .|. . |.||   .|   .  |.|.  ||.   .||   .|||||.    ..|...|||.        . .|. 
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTT--KPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVT

VTVL
.||.
ITVC
CA 2269.AA CA 4398-4478 24 1.1e-16 62.69 SMART 1-121 (121) Show / Hide 
Range on Protein: 4398-4478
Range on HMM: 1-121/121
Sequence Identity: 24% (31 aa)

ITGTDADEG---ANAV------ISYYIANSTAMARFAIDSVTGN-----------LTCA-DLDYEES---------IREMIIVGLTDGLPGS--------
.| ||.|||    |.       ..| | .      |.||. ||.           .| .  ||.||           .  ..|  ||| . .        
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTR

-------NDSFVTINVNVTDVNDEAP
         | .|....|.|||| .|
KFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 4401-4471 28 4.8e-09 34.19 Pfam 21-102 (102) Show / Hide 
Range on Protein: 4401-4471
Range on HMM: 21-102/102
Sequence Identity: 28% (23 aa)

TDAD--EGANAVISYYIANSTA--MARFAIDSVTGN---LTCA-DLDYEES-IREMIIVGLTDG--LPGSNDSFVTINVNVT
||.|  .|.|. |.| | .        |.||. ||    .|..  ||.|.   .  ..| .||.   . . .| .|....|.
TDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTITVC
CA 2269.AA CA 4501-4583 30 5.5e-28 100.22 SMART 1-121 (121) Show / Hide 
Range on Protein: 4501-4583
Range on HMM: 1-121/121
Sequence Identity: 30% (39 aa)

VVAFDRDTG---SGGV------VRYALTAADNCTAFFTVDPVTG-----------VLETVTRLDRERQ---------ETFTCVVLAADQGSPS-------
|.| |.|.|   . |       |.| ..       .|..|| ||           .. |. .|||| |         ...| .| | |.|.|.       
VTATDPDEGHNGPNGQPNDPEMVTYSIVG------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPT

--------LSSTTTVDIVVLDRNDNEP
        ||||.|| | ||| ||| |
RKFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 4484-4576 34 3.1e-19 69.67 Pfam 1-102 (102) Show / Hide 
Range on Protein: 4484-4576
Range on HMM: 1-102/102
Sequence Identity: 34% (35 aa)

TYYDVFENEFDGAVVAQVVAFDRD--TGSGGVVRYALTAADN-CTAFFTVDPVTGV---LETVTRLDRERQ-ETFTCVVLAADQ--GSPSLSSTTTVDIV
    | ||.  |  |..| | |.|  .|  . ..|...  .      |..|| ||.   . |. .|||| | .... .|.| |.  |.|..|||||| | 
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VL
|.
VC
CA 2269.AA CA 4605-4681 27 5.1e-28 100.33 SMART 1-121 (121) Show / Hide 
Range on Protein: 4605-4681
Range on HMM: 1-121/121
Sequence Identity: 27% (34 aa)

VSATDADTP---ANTN------ISFGLLEPSAAFGIDPLSG-----------SLFTKIALDRETR---------EMYELTLTVSDGQ-------------
|.|||.|..    | .      ... ...    | ||| .|            ..|. .||||..         . |.|| ...||              
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----LSSTATALITVTDVNDNGP
     ||||.|  |.|.||||| |
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 4590-4674 34 4e-20 72.79 Pfam 1-102 (102) Show / Hide 
Range on Protein: 4590-4674
Range on HMM: 1-102/102
Sequence Identity: 34% (35 aa)

YAFDVAELFL-GQFA-SVSATDAD--TPANTNISFGLLEPSA----AFGIDPLSGS---LFTKIALDRETR-EMYELTLTVSDG-----QLSSTATALIT
| | | |    |.|  .| |||.|  ...|..|.. .|...      | ||| .|.   ..|.  ||||.. ..|.||. ..|.      .|||.|  ||
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VT
|.
VC
CA 2269.AA CA 4704-4782 27 6.1e-27 96.75 SMART 1-121 (121) Show / Hide 
Range on Protein: 4704-4782
Range on HMM: 1-121/121
Sequence Identity: 27% (34 aa)

LIVTDADIG---LNAE------VNYTLLGNVSLFEMDH-TG-----------RLYTLGPLDRELQ---------ASYFLSVLVQNTAPPY----------
. .||.| |    |..      | |...|   .|..|  ||            ..|..||||| |         ..| | | ... ..|           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----FSTTATVSVTVLDINDNAP
     .|.|.|| ..|||.|||.|
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 4687-4775 33 2.7e-18 66.4 Pfam 1-102 (102) Show / Hide 
Range on Protein: 4687-4775
Range on HMM: 1-102/102
Sequence Identity: 33% (34 aa)

TNGAVTENMPFNETVLQLIVTDAD--IGLNAEVNYTLLGNVS----LFEMDH-TGR---LYTLGPLDRELQ-ASYFLSVLVQNT--APPYFSTTATVSVT
 .. | || | . .|... .||.|   |.|. . | .||. .     |..|  ||.   ..|  ||||| |   | |.|....   ..|  |.|.|| .|
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VL
|.
VC
CA 2269.AA CA 4806-4884 24 1.1e-20 75.93 SMART 1-121 (121) Show / Hide 
Range on Protein: 4806-4884
Range on HMM: 1-121/121
Sequence Identity: 24% (30 aa)

LEVTDSDVG---TNAQ------VTLSVFDPIGKIDIDASGQ------------LLLIGELDREAL---------AAFEIMIMAIDAGTPQ----------
. .|| | |   .|.|      || |. .   . .||...             . . ..||||.          . ... . | |.|.|.          
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----LSTNITIMINVEDVNDNAP
     ||.. |. |.|.|||||.|
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 4789-4877 27 2.2e-13 49.33 Pfam 1-102 (102) Show / Hide 
Range on Protein: 4789-4877
Range on HMM: 1-102/102
Sequence Identity: 27% (28 aa)

MSVSIPENAPLGLLPVELEVTDSD--VGTNAQVTLSVFDPI----GKIDIDA-SGQ---LLLIGELDREAL-AAFEIMIMAIDA--GTPQLSTNITIMIN
 ..|..|||| |  .  . .||.|   |.|.... |   .     ..  ||  .|.   . .  .||||.    ... .|| |.  |.| .|.  |. |.
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VE
|.
VC
CA 2269.AA CA 4908-4982 20 4.4e-15 57.35 SMART 1-121 (121) Show / Hide 
Range on Protein: 4908-4982
Range on HMM: 1-121/121
Sequence Identity: 20% (25 aa)

VHATESDL-----NET------TTYAVEDNNYLGVNSSSG-----------ELILLAALDRESF---------VELFVQVSATDVVG-------------
|.||  |      |         || ...  .  .....|           .......||||.           .  ..| |||  |             
VTATDPDEGHNGPNGQPNDPEMVTYSIVG--WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKFQ

----NNATARVELTITDVNDNAP
      .|. |  ...|||||.|
QNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 4891-4975 20 9e-06 22.72 Pfam 1-102 (102) Show / Hide 
Range on Protein: 4891-4975
Range on HMM: 1-102/102
Sequence Identity: 20% (21 aa)

YEYDVPEDLALGPMGLYVHATESD----LNETTTYAVEDNN-----YLGVNSSSGE---LILLAALDR---ESFVELFVQVSAT-D-VVGNNATARVELT
|.  |.|. . |.. . |.|| .|    .|.  .|.   .|        ... .|.   . . . |||   .. ..| | ..   |   .  .|..|  |
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

IT
..
VC
CA 2269.AA CA 5004-5087 23 5.7e-21 76.91 SMART 1-121 (121) Show / Hide 
Range on Protein: 5004-5087
Range on HMM: 1-121/121
Sequence Identity: 23% (30 aa)

VSATDADEG-LAGTAG------IRFRLVDNPNNLSLTVDATSG-----------LITLTAAIDYEVL---------PNATFVVEAYNLLDSS--------
|.|||.|||     .       .....|.       ..|...|            ||.|...|.|           |. |..|.| .    .        
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTR

-------LATSVEVTVVVLDVNDNAP
       | ....||. |||||||.|
KFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 4989-5080 22 1.7e-12 46.25 Pfam 1-102 (102) Show / Hide 
Range on Protein: 4989-5080
Range on HMM: 1-102/102
Sequence Identity: 22% (23 aa)

YSTSISEG-QTGALL-SVSATDADEGLAGTAGIRFRLVDNPN--NLSLTVDATSGL---ITLTAAIDYEVL-PNATFVVEAYNL--LDSSLATSVEVTVV
|. |..|. ..|  . .| |||.|. |.  ..|..... ..   .   ..|  .|    ||.|. .|.|   .  ...|.| .      .. . ..||. 
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VL
|.
VC
CA 2269.AA CA 5111-5186 19 9.5e-16 59.57 SMART 1-121 (121) Show / Hide 
Range on Protein: 5111-5186
Range on HMM: 1-121/121
Sequence Identity: 19% (24 aa)

FTASDVDV----SSTL------LSFYLRSADGVFAVGEVTG-----------VLSPLINLDRETR---------AAYAIIVGCSDGS-------------
.||.| |     ..        ... . .    |.. . ||           ... .  ||||..         . | ..|  .||              
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----FTVEKTVQVSVLDQNDNEP
     .. . ||.. |||.||| |
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 5094-5179 23 7.5e-12 43.98 Pfam 1-102 (102) Show / Hide 
Range on Protein: 5094-5179
Range on HMM: 1-102/102
Sequence Identity: 23% (24 aa)

TSVSVTENAPLSTVMAQFTASDVD---VSSTLLSFYLRSAD----GVFAVGEVTGV---LSPLINLDRETR-AAYAIIVGCSDG-----SFTVEKTVQVS
 ..|| ||||  |  ...||.| |      . ... . . .    . |.. . ||.   ..   .||||..   | ..| ..|.     . . . || ..
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VL
|.
VC
CA 2269.AA CA 5211-5306 20 2.1e-15 58.45 SMART 1-121 (121) Show / Hide 
Range on Protein: 5211-5306
Range on HMM: 1-121/121
Sequence Identity: 20% (27 aa)

FAATDADL-----NSN------ITFALVNTTRAGVFAVSPDG------------VLSLASLLDYENW---------TMATVVVRADDNGGPAVTVGSNMT
. |||.|      |..      .|. .|.      |.. |..            .....  ||.|.             |..|.| |.|||    ... |
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHP-T

GAALTPCK-----GHCTDHVIVLNVEDANDNAP
     . |     .. .   .. .|.| |||.|
-----R-KFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 5194-5272 25 4.8e-10 37.69 Pfam 1-92 (102) Show / Hide 
Range on Protein: 5194-5272
Range on HMM: 1-92/102
Sequence Identity: 25% (23 aa)

SNLSLSEGAAIGDVFYTFAATDAD----LNSNITFALVNTTR--AGVFAVSP-DGV---LSLASLLDYENW-TMATVVVRADDN--GGPAVT
 . |..|.|..|    |..|||.|    .|..|....... .  .. |.. | .|.   ....  ||.|    . ...|.| |.  |||. .
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRS
CA 2269.AA CA 5330-5409 23 4.3e-28 100.56 SMART 1-121 (121) Show / Hide 
Range on Protein: 5330-5409
Range on HMM: 1-121/121
Sequence Identity: 23% (29 aa)

VNASDADSG---VNAE------VRFSVTMGGSIFAIDAVSG-----------VLSVSGTLDFESE---------ETIQVQIMATDQGTPA----------
|.|.|.|.|    |..      |..|..     |.||. .|           .......||.|.          .. .... |||.|.|           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----LTATATVLVQLTDFNDNAP
     |..|.|| ....| |||.|
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 5313-5402 28 3.8e-24 86.8 Pfam 1-102 (102) Show / Hide 
Range on Protein: 5313-5402
Range on HMM: 1-102/102
Sequence Identity: 28% (29 aa)

QEITISESLTVGTPVAQVNASDAD--SGVNAEVRFSVTMGGS----IFAIDAVSGV---LSVSGTLDFESE-ETIQVQIMATDQ--GTPALTATATVLVQ
......|   |||.|..|.|.|.|  .| |. ...| . |..    .|.||  .|.   ...   || |.  ..  . .||||.  |.|....|.|| ..
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

LT
..
VC
He_PIG 2269.AA He_PIG 5386-5406 37 31.803311 0.27 Pfam 38-61 (61) Show / Hide 
Range on Protein: 5386-5406
Range on HMM: 38-61/61
Sequence Identity: 37% (9 aa)

QGTPALT---ATATVLVQLTDFND
.|||. |    | |. |. || . 
SGTPTTTVQPGTYTFTVTATDASG
CA 2269.AA CA 5433-5513 22 2.2e-25 91.54 SMART 1-121 (121) Show / Hide 
Range on Protein: 5433-5513
Range on HMM: 1-121/121
Sequence Identity: 22% (28 aa)

WAASDLDSG---INAV------LSYSLQNDFSGLFALQSTTG-----------LLSLEQSLDYEMR---------QAYDLTIIVQDSGTPS---------
  |.|.|.|    |.       ..||. .    .|.. ..||            ... ..||.| .         . | ||....|.|.|.         
VTATDPDEGHNGPNGQPNDPEMVTYSIVG----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRK

------LSTSMVLRINVGNVNDNAP
      ||..  ..|.|  ||||.|
FQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 5417-5506 23 2e-17 63.37 Pfam 1-102 (102) Show / Hide 
Range on Protein: 5417-5506
Range on HMM: 1-102/102
Sequence Identity: 23% (24 aa)

TSIMVAEDTT-PSNLGVWAASDLD--SGINAVLSYSLQNDF---SGLFALQSTTGL---LSLEQSLDYEMR-QAYDLTIIVQDS--GTPSLSTSMVLRIN
 .. | |..  .. ... .|.| |  .| |. ..||. ..    .. |.... ||    ... ..||.| . . | ||....|.  |.|..|.  ...|.
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VG
| 
VC
CA 2269.AA CA 5536-5614 21 2.1e-21 78.34 SMART 1-121 (121) Show / Hide 
Range on Protein: 5536-5614
Range on HMM: 1-121/121
Sequence Identity: 21% (27 aa)

VQATDADGD------V------LRYRLQPTEHADAFGLQATSG-----------VLVLRDALDYEAV---------QQVDLVIEAYDTTANP--------
|.|||.| .             ..|.. .      | . ...|           ..... .||.|.          .|  |...| |   .|        
VTATDPDEGHNGPNGQPNDPEMVTYSIVG-----WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTR

-------LRATLNLTIHILNVNDNAP
       | .|  .|||.| ||||.|
KFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 5520-5607 23 5e-14 51.54 Pfam 1-102 (102) Show / Hide 
Range on Protein: 5520-5607
Range on HMM: 1-102/102
Sequence Identity: 23% (24 aa)

QTLEVEENAE-FVTLVTVQATDAD-----GDVLRYRLQPTEH--ADAFGLQATSGV---LVLRDALDYEAV-QQVDLVIEAYDT--TANPLRATLNLTIH
.. .|.|||    .. ||.|||.|        ..|.. ...   .. | ..  .|.   . ..  ||.|.  .|. |...| |      |...|  .||.
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

IL
..
VC
He_PIG 2269.AA He_PIG 5534-5543 70 8.063118 2.36 Pfam 52-61 (61) Show / Hide 
Range on Protein: 5534-5543
Range on HMM: 52-61/61
Sequence Identity: 70% (7 aa)

VTVQATDADG
.||.|||| |
FTVTATDASG
CA 2269.AA CA 5638-5713 27 1.7e-23 85.3 SMART 1-121 (121) Show / Hide 
Range on Protein: 5638-5713
Range on HMM: 1-121/121
Sequence Identity: 27% (34 aa)

TTATDLDA-----SDT------LTYTVSGAPGVVVINSTSG-----------QLSTEAGLDYEQM---------QSYTLTVVAEDQGG------------
 ||||.|.     .        .||...|      |....|           ...| . ||.|..         ..|||||.| |.||            
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----LVGTALVYVTVLDVNDNHP
     | .|. | ..||||||| |
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 5621-5706 29 1.9e-18 66.92 Pfam 1-102 (102) Show / Hide 
Range on Protein: 5621-5706
Range on HMM: 1-102/102
Sequence Identity: 29% (30 aa)

YSVDVSESTAIGTTILTTTATDLD----ASDTLTYTVSGAP----GVVVINSTSGQ---LSTEAGLDYEQM-QSYTLTVVAEDQ-G---GLVGTALVYVT
|.. |.| ...||...| |||| |    .   ..|  .| .    .   |.. .|.   ..| . ||.||. . |.|||.| |. .   .. .|. |..|
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VL
|.
VC
He_PIG 2269.AA He_PIG 5650-5694 26 0.035447 10.62 Pfam 1-61 (61) Show / Hide 
Range on Protein: 5650-5694
Range on HMM: 1-61/61
Sequence Identity: 26% (17 aa)

TYTV-----------------SGAPGVVVINSTSGQLSTEAGLDYEQMQ-SYTLTVVAEDQGG
|||.                 .| |    .|||.| .|     .. . . .|| || | | .|
TYTATKPKDGSTTTYSTTPGGNGLPAGLTFNSTTGTISGT--PTTTVQPGTYTFTVTATDASG
CA 2269.AA CA 5740-5820 27 4.5e-25 90.54 SMART 1-121 (121) Show / Hide 
Range on Protein: 5740-5820
Range on HMM: 1-121/121
Sequence Identity: 27% (34 aa)

FEATDADLE---VGNV------VSYALENSSALFRIEAETG-----------ILYTTAPLDAEVQ---------RVYSLWVRAIDNGSPPL---------
. |||.| .             |.| ...   .|.|...||           ...||.||| | |          .|.| |.| |.|.||          
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----SSALVAVVINVTDLNDNSP
      |. . |.|.|.| ||| |
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 5720-5813 34 1.6e-18 67.18 Pfam 1-102 (102) Show / Hide 
Range on Protein: 5720-5813
Range on HMM: 1-102/102
Sequence Identity: 34% (37 aa)

YAGAVPENAAANTAIAMSSVFEATDAD--LEVGNVVSYALENSSA----LFRIEAETGI---LYTTAPLDAEVQ-RVYSLWVRAIDN--GSPPLSSALVA
| . |.|||. .| ..   .. |||.|  |     ..|.. . .      |||. .||    ..||.||| | | . |.|.|.| |.  |.||.||  . 
YHFSVCENAPVGTFVM---TVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTT-

VVINVT
|.|.|.
VTITVC
CA 2269.AA CA 5868-5947 23 2.6e-22 81.34 SMART 1-121 (121) Show / Hide 
Range on Protein: 5868-5947
Range on HMM: 1-121/121
Sequence Identity: 23% (29 aa)

VAASDLDVG---TNAD------ITFTFATASTTLAIDASSG-----------AISLTAGVDREVT---------EELEVVVVATDGGSPA----------
| |.|.| |   .|..      .|...       .||...|            |..|.  ||| .         .. ...|.|||||.|           
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDSHPTRKF

-----RAVEALVRLSVEDRNDNSP
     .  .. |.  |.| ||| |
QQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 5854-5940 28 1.5e-12 46.41 Pfam 1-102 (102) Show / Hide 
Range on Protein: 5854-5940
Range on HMM: 1-102/102
Sequence Identity: 28% (29 aa)

DNFELC-D--VGRVLLTVAASDLD--VGTNADITFTFATAST----TLAIDASSGA---ISLTAGVDREVT-EELEVVVVATDG--GSPARAVEALVRLS
 .|..| .  ||  ..||.|.| |   |.|. |.. .   .     . .||  .|    |..|. .||| . .. ...|.|||.  |.|.|  .. |. .
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPDPGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVTIT

VE
|.
VC
He_PIG 2269.AA He_PIG 5892-5926 27 1.239798 5.21 Pfam 28-61 (61) Show / Hide 
Range on Protein: 5892-5926
Range on HMM: 28-61/61
Sequence Identity: 27% (10 aa)

LAIDASSGAISLTAGVDREVTE-ELEVVVVATDGGS
| .....|.|| |  ..  |.  .  . | |||.. 
LTFNSTTGTISGT--PTTTVQPGTYTFTVTATDASG
CA 2269.AA CA 5971-6055 22 9.2e-19 69.57 SMART 1-121 (121) Show / Hide 
Range on Protein: 5971-6055
Range on HMM: 1-121/121
Sequence Identity: 22% (29 aa)

LTATDPDES---GAAT------VNYFLVDASNRIQTHDSFVVGQSSG-----------IVSTRRSLDYETD--------APTYELRVAAVDQDE------
.|||||||      .       | | .|.          | . ...|           ...|...||.|.         .|.|.|.| |.|...      
VTATDPDEGHNGPNGQPNDPEMVTYSIVG---------WFSIDPNTGTNYPSLVYCEIWITTTKPLDREEQFNKNEQRHHPQYTLTVQATDGGGPPPPDS

-----------NLAVAIVRVALLDVNDLAP
             . . |.. .||||| .|
HPTRKFQQNPPLSSTCTVTIHVLDVNDNPP
Cadherin 2269.AA Cadherin 5954-6046 23 4.1e-11 41.39 Pfam 1-102 (102) Show / Hide 
Range on Protein: 5954-6046
Range on HMM: 1-102/102
Sequence Identity: 23% (24 aa)

VNLTLAENTPANSVLVTLTATDPD--ESGAATVNYFLVDASNRIQTHDSFVVGQSSGI---VSTRRSLDYETDAPTYELRVAAVDQ-D-----ENLAVAI
 . .. ||.| .. . |.||||||  .   . . |...  . .    . | . . .|    ..|...||.|. ...|.| | |.|. |     .. .. .
YHFSVCENAPVGTFVMTVTATDPDDPLGPNWRIFYSILGGNPD--PGHWFRIDPDTGDNGIITTTKPLDREQQNGQYHLTVMATDHDDGGPPRSSTTTVT

VRVA
. | 
ITVC
PTPc 2269.AA PTPc 6633-6900 30 1.6e-104 354.45 SMART 1-308 (308) Show / Hide 
Range on Protein: 6633-6900
Range on HMM: 1-308/308
Sequence Identity: 30% (96 aa)

QIDAEFDAIKHDSESS-------PFTFKAATETYNV--KKNRYG-NVLPIDDTRVLLSHTGQ-----LGSDYINANYIPSWTRDNAFIASQGPIASTVGD
.. .||. ..             . ... |    |.  .||||  .....|.||| |...        ||||||||||..  | ...|. |||  .|. |
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRMIWETNSSSIIMMTREVEE--------GRLKCYKYWPEPEVPMRVGGYSIVALDYTNLSPEYGVRTLRLIDLET--------NEARIIKQFDYFSWP
||||.|. ....|.|.....|         || || .|||.   ||  |....  .........| .||... . ..        .| |..... | .||
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP

DGGAPPTAVGFIRFVLDVKQHIEAARS--------------GNEVGPPVVHCSAGIGRTGTFLAMYALMQRLESLGNVDVAATVAYLRMYRAGLVQTVVQ
| |.|... .|..|. .|... .  .                   ||.|||||||.||||||.|. ...|..|    ||.  .|  .|..|.|.|||  |
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQ

YRFLYEAIVTYYK
|.|.|..|  |.|
YIFCYRCILEYIK
Y_phosphatase 2269.AA Y_phosphatase 6660-6897 37 4.5e-101 346.89 Pfam 1-243 (243) Show / Hide 
Range on Protein: 6660-6897
Range on HMM: 1-243/243
Sequence Identity: 37% (93 aa)

NVKKNRYGNVLPIDDTRVLLSHT-GQLGSDYINANYIPS-WTRDNAFIASQGPIASTVGDFWRMIWETNSSSIIMMTREVEEGR-LK-CYKYWPE--PEV
| .|||| .... |.||| |... |  .|||||||||.. ... .|.|. |||  .|..|||||.|. ....|.|.....| ||  | |..|||.   . 
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

PMRVGGYSIVALDYTNLSPEYGVRTLRLIDLET--NEARIIKQFDYFSWPDGGAPPT-AVGFIRFVLDVKQHIEAARSGNEVGPPVVHCSAGIGRTGTFL
||. |....   ...   |.| |||... . ..  .| |..... | .||| |.|.. . ....|.  |... .  ..|   .|.|||||||.|||||| 
PMTYGDFQVTCVSEEH-CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGC--PPIVVHCSAGCGRTGTFC

AMYALMQRLESLGNVDVAATVAYLRMYRAGLVQTVVQYRFLYEAIVT
|. ...|..|  | ||.  .|  .|  |.|.|||  ||.|.|..|. 
AIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
PTPc_motif 2269.AA PTPc_motif 6791-6897 35 7.8e-37 129.61 SMART 1-92 (92) Show / Hide 
Range on Protein: 6791-6897
Range on HMM: 1-92/92
Sequence Identity: 35% (40 aa)

IIKQFDYFSWPDG-----GAPPTAVGFIRFVLDVKQHIEAARSGNEVGPPVVHCSAGIGRTGTFLAMYALMQRLESLGNVDVAATVAYLRMYRAGLVQTV
..... | .|||      |.|    ....|.  |..            |.|||||||.|||||| |.. .||.      ||.  || ..|..|.|.||| 
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK------------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTE

VQYRFLYEAIVT
 ||.|.|..|  
EQYIFCYRCILE