Gene 9618 (M.brevicollis)

9618

Species: M.brevicollis
Alias: 9618
External Links:
Annotation:

Classification

Group: TK-assoc
Family: PTP

Sequence

Name Sequence Type Origin Length Description Download
9618.AA Protein None 2296 None Fasta, JSON

Protein domain

Protein domains of 9618.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 9618.AA MYSc 246-1032 30 1.2e-228 766.75 SMART 1-771 (771) Show / Hide 
Range on Protein: 246-1032
Range on HMM: 1-771/771
Sequence Identity: 30% (263 aa)

SKPHKA--SDNLARYNDITEDYIVGTLQLRYRDGLIYTAVGDILVAVNPYQEV-GLYSDEWKAAYMFD------SDISRRPHIFGIALRAFRAMANEGVD
  |.|    | ...  ...|. .. .|. ||. ..|||  |....|||||..  ..|.... ..|...      .     |||| || .|.|.| |.. .
MNPPKFEGVDDMCMLTYLNEPAVLHNLKKRYMNDQIYTYIGPVCIAVNPYKQLPPIYTPDVIKQYRNRKFDDGKHRYEMPPHIFAIADNAYRNMLNDKEN

QSCVISGESGAGKTETAKLFLRHLLDLSGGNIQELLHRYDLMQFSINN-------LLEAFGNAQTRINRNSSRFGKYVELGFSRDNHALGVMLSTYLLEK
|...|||||||||||..|. ...|  .||               .. .       .||||||| |  | ||||||||.|. |..  .  |   ..|||||
QCIIISGESGAGKTENTKKIMQYLAAVSG------------QVERVEQQILQSNPILEAFGNAKTVRNNNSSRFGKYMEIHFDEKGKICGAKIENYLLEK

SRVVHQSCPSHVMHNARLPPNTGLQSEGERNFHIFYYLVEGLSDAERKQYHLDG---TIRDFAYINGGVTPYERARTGR----QSDLAGMP-AETPLLYR
||||.                   |..||||.||||.| .|.|.......||.    .. |..|.| | . | .    |    .....|.  ||    ..
SRVVY-------------------QNKGERNYHIFYQLCAGASEEQKQEFHLKPFSHNPEDYHYLNQGGH-YWNN-K-RHQSQCFTVDGIDDAEE---FK

E----LIDYMKLAGFSAIELEYIHQMLALVLLLGNIDFDRDSR--GKGQRFM-KLDVIGPLEAVAALLGCTVSDVGHGLASTIMVTRGD---TIVKENTQ
|    ..  |.  |||. | | | . .| .|.||||.|  . .  . .. .. | .    |.... |||....|  . | . .|.|...   .|.| ...
ETCEQTCNAMRVMGFSEEEQEWIFRIVAAILHLGNIEFEQGRNQYDNQAVCSEKVKDEEELQNACELLGVDPEDLEKWLTHRKMKTGHEGGTWITKPLNV

QDAKDARDAMAKALYGRLFFWVVNKVNLLLGLHDMSQVKRTIGVLDIFGFESLKVNSLEQMCINIANEQLQEFFNSHIFAWQQQELTEEGIDASFVSFT-
. | .||||.|||.|.||| |.|...|  .        ...||||||.|||. ..||.|| ||| .||.|| ||| |.|   |.|  .|||. .|. |. 
EQAIYARDALAKAIYSRLFDWIVKRINQSM-------HNYFIGVLDIYGFEIFEHNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYQREGIEWTFIDFFM

-DNSSLLNLFIGN---PVGLLNLVDEQSRF---PNADDQSLIDKLANQL----SQHNTIFTKG----------KKSKKLHFTIQHYAGPIDYDVTGWIEK
 ||   ..|  .    | |.. | ||...|   |.. ||....|| .|.       .. |.|           |. .. ||.|.|||| ..|.|.||.||
YDNQPCCDLIEKKGKRPMGIFSLLDEECMFHAQPKGTDQTFLEKLNKQDYHQHHKNHPHFSKPHKSHRCCKPKKRMGRTHFIIKHYAGDVTYNVEGWLEK

NRDSLTPSVTSLLRESQNVLVRDLFSTSQTLFGGLTANEPQALRDQRQENARELIKVLRRSFWNPSKQEKASENRRQVLRANGGGGGGRMQRLDSQPSLP
|.| | ... .|...|.| ....||. . .  .  . ..      .  ....  . ... .                                       
NKDTLFDDLIQLMQSSKNPFIKQLFPEYEDQTSQTPQEKSS-QGKNKSRRKKR-M-MQM-K---------------------------------------

VSK--TVKKASTTICASFKASLNDLVTKLSQTEPSFVRCIAPNHDQKPNDYVEAEVLRQLRYTGVMETIRIRREGFAVRLFFDEFVARYRLLHYRFKQGL
  |  ..||  .|. . || .||.|...|....| ..||| ||. .||.|...  ||.|||. ||.|.|||||.||..|. ..||. ||..|   . .  
--KTCMQKKRFPTVGFQFK-QLNELMETLNSCHPHYIRCIKPNEEKKPWDFDDDLVLHQLRCCGVLENIRIRRAGFPYRWPYQEFYQRYKMLCPPTWPNW

A--------AEPVDACKQILSSFS-------EDPSEWQLGKSKVFLK-YSVMAKLLNALEE
           | .||..|| .          ||...|.||.|||.. . ... |  . |.
GNPWKNQLFGDPKKACEAILQQLGEYIQHQNWDPDMYQFGKTKVFFRNPGQLFHLEEMRER
Kinase 9618.AA Myosin_head 527-814 30 3.9e-81 279.76 Pfam 256-587 (765) Show / Hide 
Range on Protein: 527-814
Range on HMM: 256-587/765
Sequence Identity: 30% (102 aa)

MKLAGFSAIELEYIHQMLALVLLLGNID-FDRDSRGK-GQRFMKLDVIGP-LEAVAALLGCTVSDVGHGLASTIMVTR----GDTIVKENTQQDAKDARD
|.. ||.. | . | . .| .|.|||.. |  | ... .     .|     .|....|.|  ...  ..| . ...|.     ....|  . . |..|||
MDIIGFTHEEQRSIFRIVAAILHLGNMKGFKQDQNEEQA----VVDDTEEICEIICELMGVDPEEFEKWLCYRRIKTGGGKRREWVTKPQNCEQAMYARD

AMAKALYGRLFFWVVNKVNLLLGLHD----------------------------MSQVKRTIGVLDIFGFESL-KVNSLEQMCINIANEQLQEFFNSHIF
|.|||.|.|.| |.||..|  .   .                              ..  .||||||.|||   ..||.||.||| .||.|| ||| |.|
ALAKAIYSRMFDWIVNRINQAICHKTQNTDDSDGQAAQWDDTVSITVVDVPDPAFDKRNYFIGVLDIYGFEIFCEKNSFEQFCINYCNEKLQQFFNHHMF

AWQQQELTEEGIDASFVSF-TDNSSLLNLFIG-NPVGLLNLVDEQSRFPNADDQSLIDKLANQLSQHNTIFTKG-KKS-K--------KLHFTIQHYAGP
   |.|   |||. .|. . .||    .|  . .|.|.| | ||...||.|.||....|| .. |...   ..  .|. .        . ||.| |||| 
KLEQEEYVREGIQWTFIDYGFDNQPCCDLIEKKKPMGILSLLDEECWFPKATDQTFLQKLYQTHSSKHPR-LHFAQKPGRFYKRHRQGNTHFIIKHYAGD

IDYDVTGWIEKNRDSLTPSVTSLLRESQN-VLVRDLF
..|...||.|||.| |.. . .|...|..  ....||
VWYNCEGWLEKNKDPLFDDLIELMWCSWDNPFMQELF
Kinase 9618.AA Myosin_head 252-436 35 6.4e-48 165.07 Pfam 1-190 (765) Show / Hide 
Range on Protein: 252-436
Range on HMM: 1-190/765
Sequence Identity: 35% (70 aa)

SDNLARYNDITEDYIVGTLQLRYR-DGLIYTAVGDILVAVNPYQEVGLYSDEWKAAYMFDSDISRRPHIFGIALRAFRAMANEGVDQSCVISGESGAGKT
 ..... . ..|. .   |. ||   .|||| .|.....||||... .|...  ..|.        |||| || .| |.| ... .|...|.||||||||
VEDMVMLTYLNEPSVLHNLKKRYMTGDLIYTYSGHFCISVNPYKQLPIYTQDMIQEYRGKHRYEMPPHIFAIADEAYRHMRHDRENQCIIICGESGAGKT

ETAKLFLRHLLDLSGGNIQELLHRYDLMQFS-------INN---LLEAFGNAQTRINRNSSRFGKYVELGFSRDNHA----LGVMLSTYLLEKSRVVHQS
| .|. ....  .||.| .          ..       |     .|||||||.|  | |||||||| |. |           |   ..|||||||||.|.
ENTKYVMQYFASVSGSNPG----------VNMGRVEQQILQSNPILEAFGNAKTTRNNNSSRFGKYMEIHFDKTGKINPTAVGGNIENYLLEKSRVVYQT
Kinase 9618.AA STE20 110-247 38 1.2e-41 144.66 In-house 114-259 (288) Show / Hide 
Range on Protein: 110-247
Range on HMM: 114-259/288
Sequence Identity: 38% (56 aa)

LEENTVAFLIKETLKAIVHMHVHHVMHRDIKGGNILLDDEYAVCLTDFDTAYPYDP----AEQATHFHAVGTPYWMAPEIAACDYPEGYAYDERCDVWSL
..|  .|.  .|.|..  . | .|..|||||..||||...  | |.||  .   ..    ..| .  . ||||||||||. .|.      ||..||.|||
MNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGPDKGYDYKCDIWSL

GVTAIELSEGQPPLFHLPRDKALGEVL--KQGPPTLKH--ADLWSK
| ||||. ||.||.| ... .|. ...  . .|||||.   . ||.
GITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSP
Kinase 9618.AA NinaC 110-247 42 1.1e-39 138.2 In-house 102-238 (267) Show / Hide 
Range on Protein: 110-247
Range on HMM: 102-238/267
Sequence Identity: 42% (58 aa)

LEENTVAFLIKETLKAIVHMHVHHVMHRDIKGGNILLDDEYAVCLTDFDTAYPYDPAEQATHFHAVGTPYWMAPEIAACDYPEGYAYDERCDVWSLGVTA
..|  .|. ..|.. .. |.| .||.|||.|| ||||  |  | | ||      |         .||||.|||||. ||       || ||||||||.||
MREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLD-STRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGITA

IELSEGQPPLFHLPRDKALGEVLKQGPPTLKHADLWSK
|||  | ||.. .   .|.  .    |||| | ..|..
IELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQ
Kinase 9618.AA MSN 110-247 44 1.1e-39 128.5 In-house 101-236 (265) Show / Hide 
Range on Protein: 110-247
Range on HMM: 101-236/265
Sequence Identity: 44% (61 aa)

LEENTVAFLIKETLKAIVHMHVHHVMHRDIKGGNILLDDEYAVCLTDFDTAYPYDPAEQATHFHAVGTPYWMAPEIAACDYPEGYAYDERCDVWSLGVTA
| |. .|.. .| |. . |.| |.|.|||||| |.|| ..  | | ||  .   |          .|||||||||. |||     .|| | |.||.|.||
LKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLD-RTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGITA

IELSEGQPPLFHLPRDKALGEVLKQGPPTLKHADLWSK
||. ||||||  .   .||  .... ||.|| .  |||
IEMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSK
Kinase 9618.AA KHS 110-247 44 3.4e-38 125.96 In-house 93-229 (258) Show / Hide 
Range on Protein: 110-247
Range on HMM: 93-229/258
Sequence Identity: 44% (62 aa)

LEENTVAFLIKETLKAIVHMHVHHVMHRDIKGGNILLDDEYAVCLTDFDTAYPYDPAEQATHFHAVGTPYWMAPEIAACDYPEGYAYDERCDVWSLGVTA
|.|  .|.. .|||... ..| .  ||||||| |||| |.  | | ||  .     |  |     .|||||||||.|| .   |  |.. ||.|..|.||
LSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQIT-ATIAKRKSFIGTPYWMAPEVAAVERKGG--YNQLCDIWAVGITA

IELSEGQPPLFHLPRDKALGEVLKQG--PPTLKHADLWSK
|||.| |||.|.|   .||  . | .  ||.||  . ||.
IELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQ
Kinase 9618.AA Myosin_head 892-1019 34 4e-38 131.25 Pfam 625-765 (765) Show / Hide 
Range on Protein: 892-1019
Range on HMM: 625-765/765
Sequence Identity: 34% (49 aa)

KTVKKAS-TTICASFKASLNDLVTKLSQT---EPSFVRCIAPNHDQKPNDYVEAEVLRQLRYTGVME-TIRIRREGFAVRLFFDEFVARYRLLHYRF-KQ
...||   .|  . || ..| |.. |.|.   .| .|||| ||. ..|..  .  || |||. || | .|||.|.||. |. .|||. |||.|  .. ..
QGKKKWFMQTVWFQFKEQCNHLMKWLYQCAWWHPHYVRCIKPNENKQPWQFDNSMVLHQLRCNGVLEINIRICRAGFPYRWTYDEFFQRYRILCPKTWWS

G----LAAEPVDACKQILSSF---SEDPSEWQLGKSKVFLK
.    .   . ..|. || .    . |..|.|.||.|.|..
WIWPEWNGDTKQGCEKILQHLSWGNMDKEEYQFGKTKIFFR
Kinase 9618.AA STE 110-248 25 2.8e-36 125.66 In-house 148-329 (359) Show / Hide 
Range on Protein: 110-248
Range on HMM: 148-329/359
Sequence Identity: 25% (49 aa)

LEENTVAFLIKETLKA-IVHMHVHHVMHRDIKGGNILLDDEYAVCLTDFDTAYPYDP--------------AEQA-THFHAVGTPYWMAPEIAACDYPEG
..|. .|. ....||.   . | ||..|||||..||||     | |.|| ..   ..              . ..    . |||| |||||.  ..    
FPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-

Y--AYDERCDVWSLGVTAIELSEGQPPLFHLPRDKALGEVLKQ---------------GPPTLKHA-----------------DLWSKP
.   ||..||.|||| |.||. .|.||.. ..  .|. . ..                .||.|..                  . ||..
RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPE
Kinase 9618.AA TAO 108-247 43 9.8e-35 110.69 In-house 94-225 (254) Show / Hide 
Range on Protein: 108-247
Range on HMM: 94-225/254
Sequence Identity: 43% (62 aa)

KLLEENTVAFLIKETLKAIVHMHVHHVMHRDIKGGNILLDDEYAVCLTDFDTAYPYDPAEQATHFHAVGTPYWMAPE-IAACDYPEGYAYDERCDVWSLG
| ..|  .| . ...|...  .| |...||||| ||||| ..  | |.||  |   .||.       |||||||||| | | |  ||  ||.. ||||||
KPMQEVEIAAICHGALQGLRYLHSHKMIHRDIKAGNILLTEHGQVKLADFGSASMVCPANS-----FVGTPYWMAPEVILAMD--EG-QYDGKVDVWSLG

VTAIELSEGQPPLFHLPRDKALGEVLKQGPPTLKHADLWSK
.| ||| | .|||| .    ||  . .  .|||.. . ||.
ITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQQNE-WSD
Kinase 9618.AA SLK 108-247 36 2.3e-31 102.97 In-house 92-230 (259) Show / Hide 
Range on Protein: 108-247
Range on HMM: 92-230/259
Sequence Identity: 36% (51 aa)

KLLEENTVAFLIKETLKAIVHMHVHHVMHRDIKGGNILLDDEYAVCLTDFD-TAYPYDPAEQATHFHAVGTPYWMAPEIAACDYPEGYAYDERCDVWSLG
. |.|. .... |... |. ..| ..|.|||.| ||||.  .  | | ||   |    . ..   |  .|||||||||. .|.      || . |.||||
HPLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTF--IGTPYWMAPEVVMCETFKDQPYDYKADIWSLG

VTAIELSEGQPPLFHLPRDKALGEVLKQGPPTLKHADLWSK
.| ||. .. ||   .   . |  . |  ||||.    |||
ITLIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSK
Kinase 9618.AA Pkinase 108-221 28 6.2e-29 103.38 Pfam 101-214 (293) Show / Hide 
Range on Protein: 108-221
Range on HMM: 101-214/293
Sequence Identity: 28% (35 aa)

KLL--EENTVAFLIKETLKAIVHMHVHHVMHRDIKGGNILLDDEYAV----CLTDFDTAYP--YDPAEQATHFHAVGTPYWMAPEIAACDYPEGYAYDER
. .  .|... | ....|... ..| . ..|||.|  |||.|... .    ...||  |    | . . .|.|  .|||..||||.      .|  |. .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTF--CGTPWYMAPEVIR----GGQYYGPK

CDVWSLGVTAIELSEGQPPLFH
.|.||.|.. .|.  |.||  .
VDMWSCGCILYEMLCGRPPFPG
Kinase 9618.AA YSK 175-240 42 2.4e-23 66.85 In-house 160-222 (257) Show / Hide 
Range on Protein: 175-240
Range on HMM: 160-222/257
Sequence Identity: 42% (28 aa)

VGTPYWMAPEIAACDYPEGYAYDERCDVWSLGVTAIELSEGQPPLFHLPRDKALGEVLKQGPPTLK
||||||||||.  .   |  .||.  |.||||.||.|.  |.||.  .   ...  . |. ||.|.
VGTPYWMAPEVICQ---EVSYYDFKADIWSLGITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLE
Kinase 9618.AA PAKA 175-247 45 5.2e-18 59.9 In-house 164-231 (260) Show / Hide 
Range on Protein: 175-247
Range on HMM: 164-231/260
Sequence Identity: 45% (33 aa)

VGTPYWMAPEIAACDYPEGYAYDERCDVWSLGVTAIELSEGQPPLFHLPRDKALGEVLKQGPPTLKHADLWSK
||||||||||.       .  |||  |.||||. |||. ||.||    |  .|.  . ..| | .|..| ||.
VGTPYWMAPEVI-----RRKQYDEKVDIWSLGIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQ
Kinase 9618.AA FRAY 175-239 45 2.2e-16 47.07 In-house 173-233 (277) Show / Hide 
Range on Protein: 175-239
Range on HMM: 173-233/277
Sequence Identity: 45% (30 aa)

VGTPYWMAPEIAACDYPEGYA-YDERCDVWSLGVTAIELSEGQPPLFHLPRDKALGEVLKQGPPTL
|||| |||||.      |    ||   |.||.|.|||||  | .|   .|  | |   |   ||.|
VGTPCWMAPEVM-----EQVHGYDFKADIWSFGITAIELATGKAPYHKYPPMKVLMLTLQNDPPSL
S_TKc 9618.AA S_TKc 72-327 15 3.8e-14 30.57 SMART 14-231 (231) Show / Hide 
Range on Protein: 72-327
Range on HMM: 14-231/231
Sequence Identity: 15% (50 aa)

QVYVGTLKSSDETIAIKMCQVNLSNPDDAERVAAEIKL-------------------------------------------------LEENTVAFLIKET
.|| .. |....  |||.           |..  ||..                                                 . | ...|.....
KVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQI

LKAIVHMHVHHVMHRDIKGGNILLDDEYAVCLTDFDTAYPYDPAEQATHFHAVGTPYWMAPEIAACDYPEGYAYDE-RCDVWSLGVTAIELSEGQPPLFH
..|. ..| |...|||.|  |||||.   . ..||  |  .         . .|||..||||.          |.  .||.||.|.. .|.  |.||   
CCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--------GYGKCKCDWWSCGCILYEMLCGYPPFP-

LPRDKALGEVLKQGPPTLKHADLWSKPHKASDNLARYNDITEDYIVGTLQLRYRDGLIYTAVGDILVAVNPYQEVGLYSDEWK--AAYMFDSDISRRPHI
   .... ....                                                                  |.| |     ... | ..|| .
--QMQMMFKKIG------------------------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA

FGIAL--------RAF
  .            |
-EALQDEWDIKCHPWF
Kinase 9618.AA FRAY 109-157 36 5.6e-14 39.48 In-house 103-151 (277) Show / Hide 
Range on Protein: 109-157
Range on HMM: 103-151/277
Sequence Identity: 36% (18 aa)

LLEENTVAFLIKETLKAIVHMHVHHVMHRDIKGGNILLDDEYAVCLTDF
...| ..|   ||.||..  .| .  .||||| ||||.... .. . ||
VFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADF
Kinase 9618.AA Myosin_head 454-494 46 3.4e-12 41.69 Pfam 189-231 (765) Show / Hide 
Range on Protein: 454-494
Range on HMM: 189-231/765
Sequence Identity: 46% (20 aa)

QSEGERNFHIFYYLVEGLSDAE-RKQYHLDGT-IRDFAYINGG
|..|||||||||.|  |.|..| .| .||. . ..|..| | .
QTPGERNFHIFYQLLAGASQQEEKKELHLTSADPKDYHYLNQS
Kinase 9618.AA PAKA 110-157 39 6.6e-12 38.21 In-house 100-147 (260) Show / Hide 
Range on Protein: 110-157
Range on HMM: 100-147/260
Sequence Identity: 39% (19 aa)

LEENTVAFLIKETLKAIVHMHVHHVMHRDIKGGNILLDDEYAVCLTDF
..|. .|. ..|.|...  .| .|. |||||  ||||. .  | .|||
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDF
Kinase 9618.AA YSK 110-157 37 1.6e-10 27.52 In-house 96-143 (257) Show / Hide 
Range on Protein: 110-157
Range on HMM: 96-143/257
Sequence Identity: 37% (18 aa)

LEENTVAFLIKETLKAIVHMHVHHVMHRDIKGGNILLDDEYAVCLTDF
..|  .|. ..| ||.   .|   . |||||  |.||  .  | | ||
FDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDF
TyrKc 9618.AA TyrKc 68-265 15 8e-06 -128.51 SMART 1-280 (280) Show / Hide 
Range on Protein: 68-265
Range on HMM: 1-280/280
Sequence Identity: 15% (47 aa)

INIQ---------QVYVGTLKSSDETIAIKMCQVNLSNPDDAERVAAEIKLLEEN--------------TVA------------------------FLIK
|            .|| ||.|   .. |.||.. .       |    |.... .               |                          .| |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ETL---------------KAIVHMHVHHVMHRDIKGGNILLDDEYAVCLTDF---DTAYPY---DPAEQATHFHAV--GTP-----YWMAPEIAACDYPE
                  .   . | ... |||.   |.|..... |  .||      | .     ... .  ..   |.       |||||        
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPECI-----N

GYAYDERCDVWSLGVTAIEL-SEGQPPLFH---LPRDKALGEVLKQGPPTLKHADLWSKPHK--------ASDNLARY---------------NDITEDY
 . . .  |||| ||.  |. . ||.|         ..   ||...    .|. .   .|.         ..| . .                ..| |. 
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEY----VKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
IQ 9618.AA IQ 1042-1054 30 6.701622 3.55 Pfam 9-21 (21) Show / Hide 
Range on Protein: 1042-1054
Range on HMM: 9-21/21
Sequence Identity: 30% (4 aa)

RMVRVYLIRRRFK
...| || |....
AWWRGYLARKHYR
PTPc 9618.AA PTPc 1209-1497 29 7.7e-87 295.73 SMART 1-308 (308) Show / Hide 
Range on Protein: 1209-1497
Range on HMM: 1-308/308
Sequence Identity: 29% (98 aa)

SLIEEIDDALHPANMYMM-----VDEPTFDALPLNLGNLADLPKNAAQLCRYK-NIVPNMDTVVKIDPLFENNVKVENSDFINANWVRGFDGRQSYIATQ
.. || ..     .   |     ....|  ..| | .             ||| .|... .| ||. |. . .   |.||.||||...|.... .||.||
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENRE---------MDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQ

GPKPNTIDHFWRMIIQHEVPLIIMATNLVEG--------DKIKCHRYWALFDGIKGQEKDPNLLVTESGIRVTTEEVAKSR-DFILRTFRLEWND-----
||.|.||..||||..|. .. |.| .|..|.        ...|||.|| .             .. . .|.||.... |   |...|||.... .     
GPLPHTIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-----------PMTYG-HITVTCKSEEKCPDDYTMRTFEVTNTGCNCKY

-----KEHFVKHLALNNWPDYGVPSSPRAVLRAIEVARDIRYRNPGQ------------------PIVVHCSAGVGRTGILVAVDIGIDMLLAGRRVNLT
     ....|.|.   |||| |||.||...|. |.. |. . ..|..                  |||||||||.|||| ..|.|| .... .   |.. 
SMACSETRTVTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIF

SIVQHMREDRGGMLQTFPQYEFAFKAIGSFAR
 ||..||. | || ||. || |  ..|  ...
QIVKMMRNQRPGMVQTEEQYIFCYRCILEYIK
Y_phosphatase 9618.AA Y_phosphatase 1249-1494 36 2.7e-82 284.48 Pfam 1-243 (243) Show / Hide 
Range on Protein: 1249-1494
Range on HMM: 1-243/243
Sequence Identity: 36% (93 aa)

AAQLCRYKNIVPNMDTVVKIDPLFENNVKVENSDFINANWVRG-FDGRQSYIATQGPKPNTIDHFWRMIIQHEVPLIIMATNLVEGDK-IK-CHRYWALF
    .|||.|... .| ||  |.       |.||.||||...| .   . ||.||||.|.||..||||..|. .. |.| .|..|. . .| ||.|| . 
NKEKNRYKDIPCYDHTRVKLQPI----PGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPD-

DGIKGQEKDPNLLVTESGIRVTTEEVAKSRDFILRTFRLEWND----KEHFVKHLALNNWPDYGVPSS-PRAVLRAIEVARDIRYRNPGQ---PIVVHCS
       .  .  .|  ...||.... .  |...|||.... .    ....|.|.   ||||.|||.| |...|. |.  |  .  ||.    |||||||
-------NKEGQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP-NPDHGCPPIVVHCS

AGVGRTGILVAVDIGIDMLLAGRRVNLTSIVQHMREDRGGMLQTFPQYEFAFKAIGS
||.|||| ..|.|| .... ..  |..  ||.|||. | || ||. ||.|  ..|  
AGCGRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
PTPc_motif 9618.AA PTPc_motif 1392-1494 37 3.3e-32 114.26 SMART 1-92 (92) Show / Hide 
Range on Protein: 1392-1494
Range on HMM: 1-92/92
Sequence Identity: 37% (40 aa)

FVKHLALNNWPDY-----GVPSSPRAVLRAIEVARDIRYRNPGQPIVVHCSAGVGRTGILVAVDIGIDMLLAGRRVNLTSIVQHMREDRGGMLQTFPQYE
.|.|.  .||||      |||.   ..|. |.  |.        |||||||||.|||| ..|.|. ...      |.   .|..||. | || ||. || 
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK--------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYI

FAFKAIGS
|  ..| .
FCYRCILE
IQ 9618.AA IQ 1917-1937 57 1e-05 22.36 Pfam 1-21 (21) Show / Hide 
Range on Protein: 1917-1937
Range on HMM: 1-21/21
Sequence Identity: 57% (12 aa)

VAAAIRIQAAFRGYRAREVMR
 .|||.|||..|||.||  .|
HRAAIKIQAWWRGYLARKHYR