14958

Species: M.brevicollis
Alias: 14958
External Links:
Annotation:

Classification

Group: TK-assoc
Family: PTP

Sequence

Name Sequence Type Origin Length Description Download
14958.AA Protein None 393 None Fasta, JSON

Protein domain

Protein domains of 14958.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Y_phosphatase 14958.AA Y_phosphatase 7-248 37 4.4e-85 293.78 Pfam 1-243 (243) Show / Hide
Range on Protein: 7-248
Range on HMM: 1-243/243
Sequence Identity: 37% (93 aa)

NKRHNRYMDILPPPQTRVVLPRIHDDPESEYYNANWVRGADGNPKAYVAAMGPLPATLTHFWRTIWESNVSAIIMATGLIEKGK-TK-CERYWPAEVDGK
||. ||| ||... .|||.|..|..|. | |.|||...| ..||||| .. ||.| |. .||| .|. ....|.| . ..|.|.  | |..|||      
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPD-NKEG

TAMHFGDIVVLSVSEAKAKGYIFTQLKVVRHG----ESRRIGHFWYNTWPDHGVPRDAERSLYPDSVLGLLHTVHKWNSKFKDQ--PTLVHCSAGIGRTG
. | .||. |  ||| . ..|. ....|   |    |.|.. |..| .||||||| .      |.|.| ... |.||...  .   |..||||||.||||
QPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPES-----QPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTG

TLIVIDHCRQLLKTQMRADPLAIIEAVRQDRPALVQHLQQFEFVHEACLK
|...|| . |.....   | . |.. .|. || .|| ..|..|.... | 
TFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

PTPc 14958.AA PTPc 1-251 29 1e-80 275.38 SMART 9-308 (308) Show / Hide
Range on Protein: 1-251
Range on HMM: 9-308/308
Sequence Identity: 29% (93 aa)

IPECV--------------------RNK--RHNRYM-DILPPPQTRVVLPRIHDD----PESEYYNANWVRGADGNPKAYVAAMGPLPATLTHFWRTIWE
...                       |.  . |||  ||.. ..|||.|......    . | | |||...|  ..||.| .. |||| |. .||| .|.
LQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY-WRPKRYICTQGPLPHTIEDFWRMVWQ

SNVSAIIMATGLIEK--------GKTKCERYWPAEVDGKTAMHFGDIVVLSVSEAKAK-GYIFTQLKVVRHG----------ESRRIGHFWYNTWPDHGV
 ....|.| . ..||        |. ||..||| |      | .|.| |  .|| | . .|. ....|  .|          |.| . |..| .||||||
QKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-----PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPDHGV

PRDAERSLYPDSVLGLLHTVHKWNSKFKDQ------------------PTLVHCSAGIGRTGTLIVIDHCRQLLKTQMRADPLAIIEAVRQDRPALVQHL
|        |||.| ....|..|.| ....                  |..||||||.|||||...|| . |....    |.. |.  .|. || .|| .
P------ESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTE

QQFEFVHEACLKYAE
.|. |.... |.|..
EQYIFCYRCILEYIK

PTPc_motif 14958.AA PTPc_motif 140-248 33 2.2e-34 121.5 SMART 1-92 (92) Show / Hide
Range on Protein: 140-248
Range on HMM: 1-92/92
Sequence Identity: 33% (38 aa)

RIGHFWYNTWPDH-----GVPRDAERSLYPDSVLGLLHTVHKWNSKFKDQPTLVHCSAGIGRTGTLIVIDHCRQLLKTQMRADPLAIIEAVRQDRPALVQ
 . |..|..||||     |||         ||.| ... |.|        |..||||||.|||||...|| . |.       | . .....|. || .||
TVHHYHYTNWPDHVEKDSGVPE--------DSILEFIRHVRK--------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQ

HLQQFEFVHEACLK
 ..|. |.....|.
TEEQYIFCYRCILE

Efhand 14958.AA efhand 329-349 33 0.020534 13.25 Pfam 1-21 (29) Show / Hide
Range on Protein: 329-349
Range on HMM: 1-21/29
Sequence Identity: 33% (7 aa)

EAERIWNMWDMDGDGRLSVSE
|....... | ||||.... |
ELKEMFKEFDKDGDGYIDFEE

EFh 14958.AA EFh 329-353 27 0.219946 1.8 SMART 1-29 (29) Show / Hide
Range on Protein: 329-353
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

EAERIWNMWDMDGDGRLSVSE----CRLQ
| .....| | ||||...  |    ..  
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL

Efhand 14958.AA efhand 355-379 36 0.00016 20.97 Pfam 1-25 (29) Show / Hide
Range on Protein: 355-379
Range on HMM: 1-25/29
Sequence Identity: 36% (9 aa)

LTTAQIREMDTNGDGFISLEEFKRF
   . ..|.|..|||.|..|||...
ELKEMFKEFDKDGDGYIDFEEFCEM

EFh 14958.AA EFh 355-383 34 0.000182 22.08 SMART 1-29 (29) Show / Hide
Range on Protein: 355-383
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

LTTAQIREMDTNGDGFISLEEFKRFHAKR
   . .|..|..|||.|..||||.. .. 
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL