Gene 24245 (M.brevicollis)

24245

Species: M.brevicollis
Alias: 24245
External Links:
Annotation:

Classification

Group: TK-assoc
Family: PTP

Sequence

Name Sequence Type Origin Length Description Download
24245.AA Protein None 923 None Fasta, JSON

Protein domain

Protein domains of 24245.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Y_phosphatase 24245.AA Y_phosphatase 34-205 24 8e-30 106.02 Pfam 1-167 (243) Show / Hide 
Range on Protein: 34-205
Range on HMM: 1-167/243
Sequence Identity: 24% (44 aa)

DAALNRSLGVLPSPRTRVCVRAGDPPLNINSRGAYINANFVRGFDHEHCYYIAAMSPTATSLLQFWLMIWENKVLSILMLSKITEQNR-DQ-CAVYWPT-
    ||.  ...  .|||..       . .  . |||||...| ...   ||..  |   ..  || |.|..|. .| || .. | .|  . |. |||. 
NKEKNRYKDIPCYDHTRVKLQPI----PGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDN

EPGVTVKLPNGMLATCTSKEEKHHGSILRRITLKWGE----EVRDLRHWQYVDWPEDSAVPMHGSSTSPDDLMHTLRAM
. | ...   ..  ||.|.|. ... ..|  .... .    |.| ..|..| .||..  || .     |....  .| .
KEGQPMTYG-DFQVTCVSEEH-CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDH-GVPES----QPKSMLDFIRQV
PTPc 24245.AA PTPc 10-496 12 4.4e-22 80.6 SMART 1-308 (308) Show / Hide 
Range on Protein: 10-496
Range on HMM: 1-308/308
Sequence Identity: 12% (69 aa)

RVDARFMRLDKQRPSPE--------QLPTWATDA----ALNRSL-GVLPSPRTRVCVRAGDPPLNINSRGAYINANFVRGFDHEHCYYIAAMSPTATSLL
 . . |.||....| ..        . .. . ..      ||.   ... ..|||.   ..      . . |||||...|. ..   ||..  |    . 
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY-WRPKRYICTQGPLPHTIE

QFWLMIWENKVLSILMLSKITEQ--------NRDQCAVYWPTEPGVTVKLPNGMLATCTSKEEKHHGSILRRITLKWGE----------EVRDLRHWQYV
 || |.|..|. .| || .. |         .|  |. ||| |   ...   ..  ||.|.| .  . ..| .......          |.| ..|..| 
DFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYG-HITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYT

DWPEDSAVPMHGSSTSPDDLMHTLRAMWQRRQGS----IDSQRQTREAEDVAGSPRMSVPRAMASSGIYSMVSRTADVMLLANTATPSLDQDTDSSTDDD
.||. ..        |||.... .|....... |    . .                                                           
NWPDHGVP------ESPDSFLDFIRQVRHWQSHSPNMYM-N-----------------------------------------------------------

LDHYDALGQAVVVDPVPHLSDRGAPNLPTKQHRRQASTDDQIDALIHSMTGLDASSTDAAPGEAAPPLPRRTTADVKMAADFQAILHDQPPSAKNIESVY
                                                                                                    
----------------------------------------------------------------------------------------------------

AEVSGPSAQAADRESAIKTVDAYEMPVLGTLDAFLQDVDHHEGLIGPERLKVV------------RHPFLVHCADGIERTGLAIALDIGMQTLSRTNSCD
                                                                 . | .||| .|. |||  .|.|| .| . .    |
----------------------------------------------------MVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VD

PIKVIDELRQDRPECISHSVQYALLYKAMLIHCH
. ... ..|. || ..    ||  .|...|  . 
IFQIVKMMRNQRPGMVQTEEQYIFCYRCILEYIK
Y_phosphatase 24245.AA Y_phosphatase 430-493 31 5e-12 43.39 Pfam 180-243 (243) Show / Hide 
Range on Protein: 430-493
Range on HMM: 180-243/243
Sequence Identity: 31% (20 aa)

PFLVHCADGIERTGLAIALDIGMQTLSRTNSCDPIKVIDELRQDRPECISHSVQYALLYKAMLI
| .||| .|. |||  .|.|| .| . . ...|  ... ..|. || ..    ||  .|...| 
PIVVHCSAGCGRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
PTPc_motif 24245.AA PTPc_motif 171-493 9 5.2e-07 28.7 SMART 1-92 (92) Show / Hide 
Range on Protein: 171-493
Range on HMM: 1-92/92
Sequence Identity: 9% (30 aa)

DLRHWQYVDWPED----SAVPMHGSSTSPDDLMHTLRAMWQRRQGSIDSQRQTREAEDVAGSPRMSVPRAMASSGIYSMVSRTADVMLLANTATPSLDQD
 ..| .| .||.     | ||        |.... .|.. .                                                           
TVHHYHYTNWPDHVEKDSGVPE-------DSILEFIRHVRK-----------------------------------------------------------

TDSSTDDDLDHYDALGQAVVVDPVPHLSDRGAPNLPTKQHRRQASTDDQIDALIHSMTGLDASSTDAAPGEAAPPLPRRTTADVKMAADFQAILHDQPPS
                                                                                                    
----------------------------------------------------------------------------------------------------

AKNIESVYAEVSGPSAQAADRESAIKTVDAYEMPVLGTLDAFLQDVDHHEGLIGPERLKVVRHPFLVHCADGIERTGLAIALDIGMQTLSRTNSCDPIKV
                                                               | .||| .|. |||  .|.|. ||        |  ..
---------------------------------------------------------------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQT

IDELRQDRPECISHSVQYALLYKAMLI
. |.|. ||  .    ||  .|...| 
VKEMRKQRPGMVQTEEQYIFCYRCILE
SH2 24245.AA SH2 510-604 27 1.2e-10 42.67 SMART 1-87 (87) Show / Hide 
Range on Protein: 510-604
Range on HMM: 1-87/87
Sequence Identity: 27% (26 aa)

MPWFHGELERADAEAVIKLYCEEEGRQIPGAFLIRQSGPDTHSFVLSFLGDDKGHMMHHRITYDEAADCFYLDS-SGARFDLIHTLVDAGIVGSLR
.||.|| . |..||.  | .      . .|.||.|.| ..  ..|||.  .  |.  | ||  ..  . .|.|  .. .|. .  ||.     .|.
QPWYHGNISREEAEQLLKNP-----GMPDGDFLVRDSESNPGDYVLSVRWK--GKVKHYRIRRNDD-GKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 24245.AA SH2 512-562 25 1.5e-08 26.93 Pfam 1-49 (81) Show / Hide 
Range on Protein: 512-562
Range on HMM: 1-49/81
Sequence Identity: 25% (14 aa)

WFHGELERADAEAVIKLYCEEEGRQIPGAFLIRQSGPDTHSFVLSFLGDD---K
|.|| . |..||   .      ... .|.||.|.|     ...||.. |.   .
WYHGKISRQEAERLLMN-----PGNPDGTFLVRESESTPGDYTLSVRDDGPGDR
PH 24245.AA PH 655-763 21 6.6e-16 60.09 SMART 1-82 (82) Show / Hide 
Range on Protein: 655-763
Range on HMM: 1-82/82
Sequence Identity: 21% (23 aa)

LRMAGWMHKRGSGGGAFSGKGWRRRWFILQDTILKYFSRPSASTANGYINLTHDTNVRVHSDKEFTIETPKRIFHLHCSDNQVQLLMNQTCPQSLNQWVS
. . ||..|..       . .|..|||.| .  | |.  .   .  | |.|..   ||.     |.| . .| ....|.            ......|..
VIKEGWLYKKS-------K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P--CFEIHH-DRTYYFQCE-----------SEEEMQEWMQ

IINAAIDSS
 |..||...
AIQKAIHNN
PH 24245.AA PH 655-761 22 5.7e-12 45.81 Pfam 1-92 (92) Show / Hide 
Range on Protein: 655-761
Range on HMM: 1-92/92
Sequence Identity: 22% (24 aa)

LRMAGWMHKRGSGGGAFSGKGWRRRWFILQDTILKYFSRPSASTANGYINLTHDTNVRVHSDKEFTIETPKRIFHLHCSDNQVQLLMNQTCPQSLNQWVS
... ||.||.|      . |.|..|||.|... | |.  .. ..  |.|.| .  .|. ..|        . .| ... |.  ...     ....|.|..
VIKEGWLHKKG------KRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDC-QVTKVPDN-----KRPHCFQIRT-DR-RTYYFQAESEEEMNDWMQ

IINAAID
 |..|. 
AIQSACR
PDK1_PH 24245.AA PDK1_PH 701-730 27 0.000187 13.3 In-house 57-92 (112) Show / Hide 
Range on Protein: 701-730
Range on HMM: 57-92/112
Sequence Identity: 27% (10 aa)

GYINLT-HDTNVRVH-----SDKEFTIETPKRIFHL
| | ..  |..|..      ..| |.|.||.|  ..
GEIPWSSKDLYVEYKPDRKNNFKHFFIHTPNRTYYF