25873

Species: M.brevicollis
Alias: 25873
External Links:
Annotation:

Classification

Group: TK-assoc
Family: PTP

Sequence

Name Sequence Type Origin Length Description Download
25873.AA Protein None 1514 None Fasta, JSON

Protein domain

Protein domains of 25873.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Ank 25873.AA Ank 158-190 36 8.4e-07 28.79 Pfam 1-33 (33) Show / Hide
Range on Protein: 158-190
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

MGNSALHTAAHFGHVDVVHLLLQYQVDCHRLNN
.|...|| |.. ||..|| .|||.  | .  ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

PDZ 25873.AA PDZ 348-424 27 4.4e-09 37.42 SMART 1-80 (80) Show / Hide
Range on Protein: 348-424
Range on HMM: 1-80/80
Sequence Identity: 27% (25 aa)

GLLGFSVVGGIEQDALPAIALSDAHSPHYEGQGYQ--------LREGDELLAVDG-HPVAGLSHAGVVDLFRQCES-----RVSLLILPLE
| ||||.||       ...  |  .     |  ..        ||.||..|.|.|  || ...|. .||. .||       .|.|.... .
GGLGFSIVG-------GIFISSVVPG----GPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG

PDZ 25873.AA PDZ 383-421 22 1.1e-05 21.99 Pfam 47-86 (86) Show / Hide
Range on Protein: 383-421
Range on HMM: 47-86/86
Sequence Identity: 22% (9 aa)

LREGDELLAVDGHPVAGLSHAGVVDLFRQCES-RVSLLIL
..||| .....| ......|. .|.. ... .  |.|.|.
IHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ

PDZ 25873.AA PDZ 339-370 33 4.840431 2.68 Pfam 1-33 (86) Show / Hide
Range on Protein: 339-370
Range on HMM: 1-33/86
Sequence Identity: 33% (11 aa)

ALTVRRG-ADGLLGFSVVGGIEQDALPAIALSD
 .|. ..   | ||||..|| .|.... |  |.
QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISE

Guanylate_kin 25873.AA Guanylate_kin 456-520 36 4.5e-10 35.96 Pfam 27-94 (198) Show / Hide
Range on Protein: 456-520
Range on HMM: 27-94/198
Sequence Identity: 36% (25 aa)

QQQPLLF-YDASVPLTTRTPEAGEVQGQTYHFV-SPQLFHFFLANKHLAEWGQ-YLDHYYGSLKRSIE
...|  |    .|| |||.| .||| |  |||| |   .    .|  . ||.| . ...||..| .|.
DEHPHKFDGRYCVPHTTRPPRPGEVDGKHYHFVSSREEMWNMIQNHEFIEWAQVFNGNMYGTSKETIR

PDZ 25873.AA PDZ 548-618 29 3.1e-05 20.47 Pfam 13-86 (86) Show / Hide
Range on Protein: 548-618
Range on HMM: 13-86/86
Sequence Identity: 29% (22 aa)

FGFGIHGGTDHR--NLPFIAHIADVAYAPSSPNRIAHGDAILRINDESTLTWSSEQCVQAITSSLN-VLTLVCM
.|| |.||.|.|  .  .|...     |.   .||  || |..||....  .. ...||||..| . ...|. .
LGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ

GuKc 25873.AA GuKc 442-617 17 0.000358 -31.7 SMART 1-203 (203) Show / Hide
Range on Protein: 442-617
Range on HMM: 1-203/203
Sequence Identity: 17% (39 aa)

RERS----GTQASLR----SVTQQQ-P---LLFYDASVPLTTRTPEAGEVQG--QTYHFVS-PQLFHFFLANKHLAEWGQYLDH-YYGSLKRSIEVRPQH
. |.    | . ...    .. .|. |    ...  ||| |||.| .||| |  . |||||  . ..   ..  . |||.| .. |||  | ..  |..|
HRRPIVLSGPSGVGKSTLKHMLMQEYPDYPKFEF--SVPHTTRPPRPGEVNGCVVDYHFVSLKEEMEQMIKHNKFLEWGEYHGNLYYGTSKETV--RQVH

KSRQAATSAIKICHLTRNAEN----VFGFGIHGGTDHRNLPFIAHIA-----DVAYAP------------SSPNRIAH-GDAILRIN----DESTLTWSS
.. . .   | . .. .  .      |             |.. .|.     ..   .            ..  | ||  .....      .| ...   
EQGKHCILDIDPQGVRQLRYARRYSYFY------------PIVIFIKPPSMEELEERLRQPCQRGTETEERIQKRLAHQAQKEMQHYPKCHHEFDYVIVN

EQCVQAI-TSSLNVLTLVC
..  .|. .  .... . .
DDLEDACYKELKEIMEQEQ

PDZ 25873.AA PDZ 546-621 19 0.000522 18.78 SMART 1-80 (80) Show / Hide
Range on Protein: 546-621
Range on HMM: 1-80/80
Sequence Identity: 19% (17 aa)

NVFGFGIHGGTDHRNLPFIAHIADVAYAPSSP----NRIAHGDAILRIND-ESTLTWSSEQCVQAITSSLN-----VLTLVCMTRT
. .|| | |        ||... .   |  .     ...  || ||..|. ... ... || |... .. .     ..||.   . 
GGLGFSIVG------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG

Guanylate_kin 25873.AA Guanylate_kin 1197-1214 38 10.446037 0.5 Pfam 181-198 (198) Show / Hide
Range on Protein: 1197-1214
Range on HMM: 181-198/198
Sequence Identity: 38% (7 aa)

NEKVDAILQHLQSKLDAE
|  .| .. ||.. |.||
NDDFDKAYWHLKEILEAE

PTPc 25873.AA PTPc 1216-1490 36 3e-110 373.47 SMART 1-308 (308) Show / Hide
Range on Protein: 1216-1490
Range on HMM: 1-308/308
Sequence Identity: 36% (120 aa)

GLQTEFSRLQSVGL-----------RHKSCATQANR--DKNRYR-NITAYDHSRVVLQVNPEE----GGCDYYNANYIAGARSPSDYIACQGPTNSSVDD
|...||.|||...            . .... ..||  |||||. .| .|||.||.|. .|.|    .| || ||||| | ..|  ||..|||  . ..|
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRMVWQQKTQCIVMVTNLEEQ--------GRMKCLKYWPDLAPGVSADDLRADELPKLQLGPYVVFFKERHEHK-LWTQRVFELEHEGE---------G
|||||||||...||| .|..|         || || .||||                ... | . | .|. . ..  .| |.||... |.          
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---------------PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSE

RMTVTQFHMTAWPDHGVPSEPSDLLYFRQAIRAAFPNP-------------------TSPMLVHCSAGVGRSGTFIAIDHMLQLILDEARAASDVPDVRD
  |||..| |.|||||||. |...| |....|.  .                     |.|..||||||.||.|||.||| |.|.| .        .|. .
TRTVTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN--------VDIFQ

VVHGMRDRRNFMVQTEEQYIFI-YFALEMAL
.|  ||. |..||||||||||.   .|| ..
IVKMMRNQRPGMVQTEEQYIFCYRCILEYIK

Y_phosphatase 25873.AA Y_phosphatase 1239-1488 42 2.2e-101 347.9 Pfam 1-243 (243) Show / Hide
Range on Protein: 1239-1488
Range on HMM: 1-243/243
Sequence Identity: 42% (111 aa)

NRDKNRYRNITAYDHSRVVLQVNPEEGGCDYYNANYIAG-ARSPSDYIACQGPTNSSVDDFWRMVWQQKTQCIVMVTNLEEQGR-MK-CLKYWPDLAPGV
|..||||..| .|||.||.||  |.....||.||||| |  ..|  ||..|||  ....||||||||||..||||..|..| ||  | | .||||     
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPD-----

SADDLRADELPKLQLGPYVVFFKERHEHKLWTQRVFELEHEG---EGRMTVTQFHMTAWPDHGVPSE-PSDLLYFRQAIRAAFP-NPTS--PMLVHCSAG
      . |  ... |.. |  .. .... .| |.||... |   . . |||..|.|.|||||||.  | ..| |.. .| . | .  .  |..||||||
------NKEGQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAG

VGRSGTFIAIDHMLQLILDEARAASDVPDVRDVVHGMRDRRNFMVQTEEQYIFIYFALEM
.||.|||.||| |.|.. .|        |. ..|  ||  |..||||||||||.| ..  
CGRTGTFCAIDIMCQQMEHEGTV-----DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

PTPc_motif 25873.AA PTPc_motif 1382-1488 41 3.7e-40 140.64 SMART 1-92 (92) Show / Hide
Range on Protein: 1382-1488
Range on HMM: 1-92/92
Sequence Identity: 41% (47 aa)

TVTQFHMTAWPDH-----GVPSEPSDLLYFRQAIRAAFPNPTSPMLVHCSAGVGRSGTFIAIDHMLQLILDEARAASDVPDVRDVVHGMRDRRNFMVQTE
||...|.|.||||     |||.  ...| |....|.       |..||||||.||.|||.||| |.|.           .|. ..|. ||. |..|||||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ-----------VDIFQTVKEMRKQRPGMVQTE

EQYIFIYFALEM
|||||.| ..  
EQYIFCYRCILE