Gene 27512 (M.brevicollis)
27512
Species: M.brevicollis
Alias: 27512
External Links:
Annotation:
Sequence
Protein domains of 27512.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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SH2 | 27512.AA | SH2 | 1-71 | 32 | 4.7e-25 | 75.39 | Pfam | 6-81 (81) | Show / Hide |
Range on Protein: 1-71 Range on HMM: 6-81/81 Sequence Identity: 32% (25 aa) MSGPDSEAALRE-RGEHGSFLVRASQSQPGRFALSVRCGD---AISHIIIRNNGGS-FDVGGGASFTDLTSLVEYY .|. . | |.. ....|.|||| |.|.|| ..||||... . |..|..... . ..|. | .| |||.| ISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY |
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SH2 | 27512.AA | SH2 | 1-77 | 34 | 1.7e-19 | 72.05 | SMART | 8-87 (87) | Show / Hide |
Range on Protein: 1-77 Range on HMM: 8-87/87 Sequence Identity: 34% (28 aa) MSGPDSEAALRER-GEHGSFLVRASQSQPGRFALSVRCGDAISHIIIRNNG-GSFDVGG--GASFTDLTSLVEYYKRKPLV .|. . |. |. . ...|.|||| |.|.|| ..||||... . |..|| |. |.. ... . .| .| ||..|.. ||. ISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG |
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PTPc | 27512.AA | PTPc | 98-383 | 35 | 2.9e-110 | 373.56 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 98-383 Range on HMM: 1-308/308 Sequence Identity: 35% (117 aa) GFNEEFEQLQTMEHQHKF-------DRMEGARIENK--SKNRYK-NILPYDHTRVKLRNVP---DGVIGADYINANFINGEAPGTDKAYIASQGTMPDTV ||.|||| ||.|. . .. . .... ||. .||||| .|..|||||||| . | .. | ||||||.|.|. . |.||. || .|.|. GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY--WRPKRYICTQGPLPHTI ADFWQMIVEQNCRLVVMATNPVEK--------GKHKCTPYWPSSERRPARFGNYVVELLTEDNFD-AYTVRRMSVAVGEG---------DPREIYQYHYT .|||.|. .|.|. .|| .|..|| |. || |||. | .|.. |... |.. . ||.| ..| ... ..|....|||| EDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYT SWPDHGVP-PEREFLQLIMKIRQHRDRLRKS-------------IPGLGPTLVHCRQVHANPRDQFQSAGIGRTGTFLVIDIVLDLIRHYGIDCDIDIQS .||||||| . ||..| ..|... ..... . ||..||| |||.||||||..|||....|.. .|| NWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHC------------SAGCGRTGTFCAIDIMCQQIEN------VDIFQ IIHKLRGQRSGMIQTAAQYRFIYKAVMDYIQ |. ..| || ||.||..||.|.|.....||. IVKMMRNQRPGMVQTEEQYIFCYRCILEYIK |
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Y_phosphatase | 27512.AA | Y_phosphatase | 125-380 | 40 | 1e-98 | 339.07 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 125-380 Range on HMM: 1-243/243 Sequence Identity: 40% (109 aa) NKSKNRYKNILPYDHTRVKLRNVPDGVIGADYINANFINGEAP-GTDKAYIASQGTMPDTVADFWQMIVEQNCRLVVMATNPVEKGK-HK-CTPYWPS-S ||.|||||.|..|||||||| . .| . ||||||.|.| | . ||||. || ||.|..|||.|. .|.|. .|| .|..|.|. | | .|||. NKEKNRYKDIPCYDHTRVKLQPI-PGDEDSDYINANYIDG--PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNK ERRPARFGNYVVELLTEDNFDAYTVRRMSVAVGE---GDPREIYQYHYTSWPDHGVPPE--REFLQLIMKIRQHRDRLRKSIPGLG--PTLVHCRQVHAN | .| ..|.. |.. |. . |||| ..| . ...|....||||.|||||||. . .|..| ..|... |. | |..||| EGQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP-----NPDHGCPPIVVHCS----- PRDQFQSAGIGRTGTFLVIDIVLDLIRHYGIDCDIDIQSIIHKLRGQRSGMIQTAAQYRFIYKAVMD ||.|||||| .|||......| |. || |. ..| || ||.||..||.|.|..... -------AGCGRTGTFCAIDIMCQQMEHEGTV---DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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PTPc_motif | 27512.AA | PTPc_motif | 259-380 | 33 | 6.2e-35 | 123.29 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 259-380 Range on HMM: 1-92/92 Sequence Identity: 33% (42 aa) EIYQYHYTSWPDH-----GVPPEREFLQLIMKIRQHRDRLRKSIPGLGPTLVHCRQVHANPRDQFQSAGIGRTGTFLVIDIVLDLIRHYGIDCDIDIQSI ....||||.|||| ||| .|..| ..|. |..||| |||.|||||| .||..... .|| . TVHHYHYTNWPDHVEKDSGVPE-DSILEFIRHVRK-------------PIVVHC------------SAGCGRTGTFCAIDMMMQQ---------VDIFQT IHKLRGQRSGMIQTAAQYRFIYKAVMD ....| || ||.|| .||.|.|..... VKEMRKQRPGMVQTEEQYIFCYRCILE |