Gene 28603 (M.brevicollis)

28603

Species: M.brevicollis
Alias: 28603
External Links:
Annotation:

Classification

Group: TK-assoc
Family: PTP
Subfamily: RPTP

Sequence

Name Sequence Type Origin Length Description Download
28603.AA Protein None 4611 None Fasta, JSON

Protein domain

Protein domains of 28603.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
VWA 28603.AA VWA 58-239 11 0.000728 10.58 SMART 1-193 (193) Show / Hide 
Range on Protein: 58-239
Range on HMM: 1-193/193
Sequence Identity: 11% (23 aa)

SIHAVFLIDGAYGVSSSAFTARKSLVARLAAAADNARGNATRYEAYEFSNFVCAVSTQCTSDP-LPSSDQLVDQLASIDQ------SYGGISRWQRAVTR
    ||.|||  ... . |.. |. . ... . |      .|. .. ||.     ...  ...  .. |.... ......      ..|| .. . |. .
WLDIVFVIDGSGSMGPNNFQQVKQFI-KFVEQLD-----GDRVGIVQFSD-----DVRVEFPLNYQDKDDVLKAIDNLQYKGKHDYFMGGGTNTG-ALQY

ATNHLTAATSSAQDTG--------LEQHIVLLASTPPH----DLNATQAALQLAVDADIQVHLLLLDPLDTSDVASLLTFNPVPI--------ADAATVN
| ..| ....  .  .          ..|.....  ..    |.  .. | . . .. .... . ...     .   .. .| .          |.   .
AMQNLFHERQG-RRGAGRPTKFWNVPKVIIVFTDGYSNDGPHDPEDIRKAARELRRSGVKIFVIGVGND-DM-ELRQIASCP-GEHHFFDVYDYDDLPDI

ATSLESSLF
.  . ..|.
FQHIIDWLC
FU 28603.AA FU 254-300 24 0.009292 15.24 SMART 1-48 (48) Show / Hide 
Range on Protein: 254-300
Range on HMM: 1-48/48
Sequence Identity: 24% (12 aa)

GTSC-QCPYQCYS-CLIYEDDSATCTQCKNGRYFWQ-GACYDDCQEASNT
.. |  |  .| . |        .|| |..|.|... |.| ..| . ...
DGVCKPCHPECATGCWGPG--PDQCTSCPHGYYLHHNGTCVSQCPPGYYP
TNFR 28603.AA TNFR 319-359 28 9.1e-05 23.09 SMART 1-50 (50) Show / Hide 
Range on Protein: 319-359
Range on HMM: 1-50/50
Sequence Identity: 28% (14 aa)

CP--AGTYRANATGDA--QACLPHT--ACSP---NTYQLRQPTATSDRIC
|.  .|.|..          |||..   |.|   ..| ..  ||||...|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 28603.AA TNFR_c6 319-359 32 0.000746 16.6 Pfam 1-41 (41) Show / Hide 
Range on Protein: 319-359
Range on HMM: 1-41/41
Sequence Identity: 32% (14 aa)

CPAG-TYRANATGDAQACLPHTACSP-NTYQLRQPTATSDRIC
|| | || .  .. .  ||. | |.| ..|  .. |.|... |
CPPGKTYTD--WNHVPHCLSCTRCHPMGQYMVQPCTWTQNTVC
Kringle 28603.AA Kringle 372-449 34 1.3e-24 86.76 Pfam 1-85 (85) Show / Hide 
Range on Protein: 372-449
Range on HMM: 1-85/85
Sequence Identity: 34% (30 aa)

CAFDDGDNANYRGQINKTSSGKTCLPWSSSVAQA-NLVTPELYPNADLRH---NYCRNPDGERT-AWCFV-EGTANAFEFCG---VC
| ...|   ||||  ..| ||..|..|.|    . .  ||| .|...|.    ||||||||..  .||..    .  .|.|    .|
CYHGNG--ENYRGTWSTTESGRPCQRWDSQTPHRHPFYTPENFPCKGLGEGKHNYCRNPDGDERGPWCYTQTDPRVRWEYCSDIPRC
KR 28603.AA KR 370-451 34 5.5e-23 83.6 SMART 1-90 (90) Show / Hide 
Range on Protein: 370-451
Range on HMM: 1-90/90
Sequence Identity: 34% (32 aa)

EGCAFD--DGDNANYRGQINKTSSGKTCLPWSSS-VAQANLVTPELYPNAD----LRHNYCRNPDG-ERTAWCFVEGTANA--FEFC--GVCST
. |  .  .|   .||| .|.| ||..|..|.|    . .  .|| .|.|.    |.||||||||| ..  ||..    |   .|.|   .|. 
RDCYWGDDNG--ESYRGTVNTTWSGHPCQRWDSQYPHLHWF-YPEWFPCAGQLGLLEHNYCRNPDGDSEGPWCYT-MDPNVRDWEYCDIPQCED
TNFR 28603.AA TNFR 495-532 18 0.205609 0.72 SMART 1-50 (50) Show / Hide 
Range on Protein: 495-532
Range on HMM: 1-50/50
Sequence Identity: 18% (9 aa)

CA--SFQYLAAN------LACVNTS-AACDS---DQIEEVAPTITSDRQC
|     .| . .        |.  .   |..   .| .    | ||...|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 28603.AA TNFR_c6 495-532 21 7.950421 2.84 Pfam 1-41 (41) Show / Hide 
Range on Protein: 495-532
Range on HMM: 1-41/41
Sequence Identity: 21% (9 aa)

CASF-QYLAAN--LACVNTSAACDS-DQIEEVAPTITSDRQC
|.   .|.. |    |..  . |.. .| .    | |....|
CPPGKTYTDWNHVPHCLSC-TRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 28603.AA TNFR_c6 560-581 40 11.36232 2.31 Pfam 20-41 (41) Show / Hide 
Range on Protein: 560-581
Range on HMM: 20-41/41
Sequence Identity: 40% (9 aa)

SVCDETTQYQVQPPTATSDRTC
..|..  || ||| |.|... |
TRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 28603.AA TNFR_c6 648-655 62 6.113144 3.23 Pfam 34-41 (41) Show / Hide 
Range on Protein: 648-655
Range on HMM: 34-41/41
Sequence Identity: 62% (5 aa)

TPTSNRVC
|.|.|.||
TWTQNTVC
TNFR_c6 28603.AA TNFR_c6 672-696 30 0.017486 11.92 Pfam 16-41 (41) Show / Hide 
Range on Protein: 672-696
Range on HMM: 16-41/41
Sequence Identity: 30% (8 aa)

CARCQTCAP-TEFENSTCTGEHDRVC
| .|..| |  ... . ||  ...||
CLSCTRCHPMGQYMVQPCTWTQNTVC
TNFR 28603.AA TNFR 661-696 18 0.036887 8.53 SMART 1-50 (50) Show / Hide 
Range on Protein: 661-696
Range on HMM: 1-50/50
Sequence Identity: 18% (9 aa)

CT--MTDATAD-------TVCARCQ--TCAP---TEFENSTCTGEHDRVC
|.    . ...         | .|.  .| |    ... . || ....||
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
FU 28603.AA FU 781-828 33 1e-06 29.58 SMART 1-48 (48) Show / Hide 
Range on Protein: 781-828
Range on HMM: 1-48/48
Sequence Identity: 33% (17 aa)

GHAC-QCSAECHS-CNLRGAASFCTKCKNGHYLYE-GRCYDDCSAFEGYIE
.. |  |..|| . |.  | .  ||.|..|.|| . |.| ..|.  .||  
DGVCKPCHPECATGCWGPG-PDQCTSCPHGYYLHHNGTCVSQCP--PGYYP
TNFR 28603.AA TNFR 805-838 18 0.152111 2.09 SMART 1-50 (50) Show / Hide 
Range on Protein: 805-838
Range on HMM: 1-50/50
Sequence Identity: 18% (9 aa)

CK--NGHYLYE-------GRC--YD--DCSA---FEGYIELGSGNFNREC
||   |||          ..|   .   |.     .. .. .. . |..|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 28603.AA TNFR_c6 863-870 37 49.972999 0.11 Pfam 34-41 (41) Show / Hide 
Range on Protein: 863-870
Range on HMM: 34-41/41
Sequence Identity: 37% (3 aa)

TATSDAIC
|.|... |
TWTQNTVC
TNFR 28603.AA TNFR 876-918 23 0.234103 0.13 SMART 1-50 (50) Show / Hide 
Range on Protein: 876-918
Range on HMM: 1-50/50
Sequence Identity: 23% (12 aa)

CFIN---YYEASAPTPTTDRQ--CKVVTSCSS---NQYQHAAPTSTSDRDC
|  .   |.. ...|  ...   |   |.|..   .||  .  |.||.. |
CKCQEGHYCHHWNHTHYEPHCLPCR-HTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 28603.AA TNFR_c6 898-918 31 21.691283 1.35 Pfam 20-41 (41) Show / Hide 
Range on Protein: 898-918
Range on HMM: 20-41/41
Sequence Identity: 31% (7 aa)

TSCSS-NQYQHAAPTSTSDRDC
|.|.. .||  .  |.|....|
TRCHPMGQYMVQPCTWTQNTVC
Herpes_gp2 28603.AA Herpes_gp2 1804-1934 48 0.000733 12.3 Pfam 150-285 (889) Show / Hide 
Range on Protein: 1804-1934
Range on HMM: 150-285/889
Sequence Identity: 48% (66 aa)

TTTEAPGTSRATNDDDNDDDDSSGSWVTSTLISTA-PTSKTPSSQSSTQTSTIIWSPSTTRQATTSEAMTTEAMNTEATTIEATTTEASTAEPTTTEATT
|||||  |. ||         .|    |.|  .|. |...|| |  .|  .| .    ||  .||  | || |  | |||  |||| | |   ||| |||
TTTEAAPTTAATTTAVTTAASTSAETTTATATTTSTPVTETPTSTTTTTATTTVPTTATTTTDTTTAATTTAATTTAATTTAATTTAATTTAATTTAATT

TEPT----TTEATTTKATTTEATTTKATTTEATTIE
|  |    || |||| |||| |||| |||| ||| |
TAATTTAATTAATTTAATTTAATTTAATTTAATTTE
Herpes_gp2 28603.AA Herpes_gp2 1935-2011 71 0.095605 4.83 Pfam 178-256 (889) Show / Hide 
Range on Protein: 1935-2011
Range on HMM: 178-256/889
Sequence Identity: 71% (58 aa)

ATTTEPTTLEATTTTPDATTTGATTTGATTTEATTTEATTTEATTTEAT----TTEATTTGATTTEATTTEATTIEATTTE
||||  ||  ||||   |||| |||| |||| |||| |||| |||| ||    || |||| |||| |||| |||  |||||
ATTTTDTTTAATTTA--ATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTAATTTAATTTAATTTAATTTAATTTE
Herpes_gp2 28603.AA Herpes_gp2 2013-2093 71 0.00097 11.87 Pfam 172-256 (889) Show / Hide 
Range on Protein: 2013-2093
Range on HMM: 172-256/889
Sequence Identity: 71% (61 aa)

TTLEATNTTPDATTTGATTTGATTTGATTTEATTTEATTTEATTTGATTTEAT----TTEATTTEATTTEATTTEATTTEATTTE
||.  | ||  .||| |||| |||| |||| |||| |||| |||| |||| ||    || |||| |||| |||| |||| |||||
TTVPTTATTTTDTTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTAATTTAATTTAATTTAATTTAATTTE
Herpes_gp2 28603.AA Herpes_gp2 2094-2181 67 0.001035 11.77 Pfam 178-267 (889) Show / Hide 
Range on Protein: 2094-2181
Range on HMM: 178-267/889
Sequence Identity: 67% (61 aa)

ATTTEATTTEATTTEATTTEATTTEATTTEATTTEATTTEATTTEATTLEATT--TTPDATTTEATTTEATTTEATTYEPTRASEATLSP
|||| .||| |||| |||| |||| |||| |||| |||| |||| |||  |||  ||  |||| |||| |||| ||| | . |.  | ..
ATTTTDTTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTTAATTAATTTAATTTAATTTAATTTAATTTESSEAATTTAAT
TNFR 28603.AA TNFR 2351-2393 22 5.8e-05 23.74 SMART 1-50 (50) Show / Hide 
Range on Protein: 2351-2393
Range on HMM: 1-50/50
Sequence Identity: 22% (11 aa)

CN--TSQFVSRQATASSDRSCTDCT--MCTP---GEYEQHACTSSGDTQC
|     .. . ..  .  . |. |.  .|.|   |.|. . ||.  .|.|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 28603.AA TNFR_c6 2351-2393 26 0.0001 19.58 Pfam 1-41 (41) Show / Hide 
Range on Protein: 2351-2393
Range on HMM: 1-41/41
Sequence Identity: 26% (12 aa)

CNTS-QFVSRQATASSDRSCTDCTMCTP-GEYEQHACTSSGDTQC
|  . .. . ....   . |. ||.| | |.|. . ||.  .|.|
CPPGKTYTD-WNHV---PHCLSCTRCHPMGQYMVQPCTWTQNTVC
TNFR 28603.AA TNFR 3910-3952 16 0.01332 13.16 SMART 1-50 (50) Show / Hide 
Range on Protein: 3910-3952
Range on HMM: 1-50/50
Sequence Identity: 16% (8 aa)

CTALEYQSIAPTPTSN--RVCTRAT--QCEE---TEYLTRAASPTSDATC
|. .| .  ..   ..  . |.. .  .|..    .|...  ..||...|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 28603.AA TNFR_c6 3921-3928 62 6.113144 3.23 Pfam 34-41 (41) Show / Hide 
Range on Protein: 3921-3928
Range on HMM: 34-41/41
Sequence Identity: 62% (5 aa)

TPTSNRVC
|.|.|.||
TWTQNTVC
TNFR_c6 28603.AA TNFR_c6 3932-3952 22 10.409537 2.44 Pfam 20-41 (41) Show / Hide 
Range on Protein: 3932-3952
Range on HMM: 20-41/41
Sequence Identity: 22% (5 aa)

TQCEE-TEYLTRAASPTSDATC
| |..  .|...   .|... |
TRCHPMGQYMVQPCTWTQNTVC
TNFR 28603.AA TNFR 3958-4001 17 0.103735 3.83 SMART 1-50 (50) Show / Hide 
Range on Protein: 3958-4001
Range on HMM: 1-50/50
Sequence Identity: 17% (9 aa)

CNA-THAFEETLATR---TSDRVCAWLTTCTE---GEFEARSATPTSDRMC
|      . .. .        . |  .|.|..   |... .. |.||.. |
CKCQEGHYCHHWNHTHYEPHCLPCR-HTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 28603.AA TNFR_c6 3981-4001 27 5.16539 3.48 Pfam 20-41 (41) Show / Hide 
Range on Protein: 3981-4001
Range on HMM: 20-41/41
Sequence Identity: 27% (6 aa)

TTCTE-GEFEARSATPTSDRMC
|.| . |... .. |.|... |
TRCHPMGQYMVQPCTWTQNTVC
TNFR_c6 28603.AA TNFR_c6 3970-3977 50 7.283654 2.97 Pfam 34-41 (41) Show / Hide 
Range on Protein: 3970-3977
Range on HMM: 34-41/41
Sequence Identity: 50% (4 aa)

TRTSDRVC
|.|...||
TWTQNTVC
TNFR 28603.AA TNFR 4007-4049 21 0.1026 3.88 SMART 1-50 (50) Show / Hide 
Range on Protein: 4007-4049
Range on HMM: 1-50/50
Sequence Identity: 21% (11 aa)

CV--TGEYEVVAPGA---SSDRQCVNLTQCAP---FEYAEMAPTVTTDRIC
|    |.|          .  ..|  .|.| |    .|.    | | ...|
CKCQEGHYCHHWNHTHYEPHCLPCR-HTRCPPEHMGQYMKQPCTATSNTVC
TNFR_c6 28603.AA TNFR_c6 4067-4074 50 7.844003 2.86 Pfam 34-41 (41) Show / Hide 
Range on Protein: 4067-4074
Range on HMM: 34-41/41
Sequence Identity: 50% (4 aa)

TATSDAVC
|.|...||
TWTQNTVC
TNFR_c6 28603.AA TNFR_c6 4078-4098 22 4.107704 3.82 Pfam 20-41 (41) Show / Hide 
Range on Protein: 4078-4098
Range on HMM: 20-41/41
Sequence Identity: 22% (5 aa)

STCSE-GEHEATAPTLTSDREC
..|.. |...    | |....|
TRCHPMGQYMVQPCTWTQNTVC
CAP_GLY 28603.AA CAP_GLY 4233-4298 43 2.3e-15 55.46 Pfam 1-72 (72) Show / Hide 
Range on Protein: 4233-4298
Range on HMM: 1-72/72
Sequence Identity: 43% (31 aa)

VGSRVYV-LGY--GWGTLRYFGLHA-TKPGARCGVEL-DTANGLNNGTVDGYWYFAA-APRHGILCDPRKVK
||.|. |  |.  . ||.|| |    .|||  .|||. | . | |.|.|.|  ||    | ||| . | ||.
VGDRCEVWDGGGGRRGTVRYVGPTPGFKPGTWVGVEWDDEPRGKNDGSVQGVRYFECRPPNHGIFVRPSKVE
PTPc 28603.AA PTPc 4345-4603 26 6e-70 239.6 SMART 1-308 (308) Show / Hide 
Range on Protein: 4345-4603
Range on HMM: 1-308/308
Sequence Identity: 26% (87 aa)

EAANTYDSIFRERQGG---------SFSSSRRNS----TKNRYT-DILAYDDTRVKLRRGI------TGSDYINANYVTFPNEEAPFYFICAQGPTSQTV
  .. .... |....          |......      .||||. ||..||.||||| ..        |||||||||. ..  . |. .||.|||   |.
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY--WRPKRYICTQGPLPHTI

DDHWQLIWENDVRVIVMVAKLQED--------GRSKCAPYWPSSDQGGLKTPSFVVEFVSQTSDDPYDRVILTTELTLIHRLT--------NERRHVTHV
.|.|. .|.. ...|||  .. |         || ||. |||.     ..   . |...| .. .     . ...... .  .        .| | ||| 
EDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCP---DDYTMRTFEVTNTGCNCKYSMACSETRTVTHY

QYLGWPDQYVLSHHLPCIMPHGVPDVDRFLALIDQVESLRAAHPRNMY-----------------TLVHCSAGIGRTGA----------------AAILR
.| .|||. |             .. | ||..| ||.. ..  | .                   ..||||||.||||.                  |..
HYTNWPDHGVP------------ESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIENVDIFQIVK

HLREQRARLVQTLQQYEFCFTAVLAKLK
..|.||. .|||..|| ||  ..|  .|
MMRNQRPGMVQTEEQYIFCYRCILEYIK
Y_phosphatase 28603.AA Y_phosphatase 4368-4570 33 1.2e-63 222.59 Pfam 1-194 (243) Show / Hide 
Range on Protein: 4368-4570
Range on HMM: 1-194/243
Sequence Identity: 33% (73 aa)

NSTKNRYTDILAYDDTRVKLRR--GITGSDYINANYVTFPNEEAPFYFICAQGPTSQTVDDHWQLIWENDVRVIVMVAKLQEDGR-SK-CAPYWPS-SDQ
|  ||||.||..||.||||| .  |  .||||||||... .   |. .||.||| . |..|.|. .|.. ...|||. .. |.||  | |..|||.  ..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG-PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEG

GGLKTPSFVVEFVSQTSDDPYDRVILTTELTLIHRLT--NERRHVTHVQYLGWPDQYVLSHHLPCIMPHGVPDVDRFLALIDQVESLRA---AH--PRNM
. ..   | |. || ..    .  . ...... .  .  .|.| ||| .|..|||. | ..           ... .| .|.||.. .    .   |   
QPMTYGDFQVTCVSEEH----CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPES-----------QPKSMLDFIRQVRKWQPNPDHGCPP---

YTLVHCSAGIGRTGA
 ..||||||.||||.
-IVVHCSAGCGRTGT
PTPc_motif 28603.AA PTPc_motif 4504-4600 27 1.7e-16 62.02 SMART 1-92 (92) Show / Hide 
Range on Protein: 4504-4600
Range on HMM: 1-92/92
Sequence Identity: 27% (32 aa)

HVTHVQYLGWPDQ-----YVLSHHLPCIMPHGVPDVDRFLALIDQVESLRAAHPRNMYTLVHCSAGIGRTGA-------------AAILRHLREQRARLV
 |.|..|..|||.      | .              | .| .|..|..          ..||||||.||||                .....|.||...|
TVHHYHYTNWPDHVEKDSGVPE--------------DSILEFIRHVRK---------PIVVHCSAGCGRTGTFCAIDMMMQQVDIFQTVKEMRKQRPGMV

QTLQQYEFCFTAVLA
||..|| ||  ..| 
QTEEQYIFCYRCILE
Y_phosphatase 28603.AA Y_phosphatase 4573-4600 46 5.8e-08 29.08 Pfam 216-243 (243) Show / Hide 
Range on Protein: 4573-4600
Range on HMM: 216-243/243
Sequence Identity: 46% (13 aa)

ILRHLREQRARLVQTLQQYEFCFTAVLA
|..|.|.||. .|||..||.||  ..| 
IVKHMRNQRPGMVQTEEQYIFCYQCILE