Gene 30339 (M.brevicollis)
30339
Species: M.brevicollis
Alias: 30339
External Links:
Annotation:
Sequence
Protein domains of 30339.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| B41 | 30339.AA | B41 | 140-358 | 23 | 2.9e-45 | 157.61 | SMART | 1-232 (232) | Show / Hide |
Range on Protein: 140-358
Range on HMM: 1-232/232
Sequence Identity: 23% (59 aa)
EQSTRFVKVHLLNGEVLMRPVHVDTFVRDVFRHVVNEIGL--HETAFFGLALMHTRE-VEFLDMERYVVSYFPTTPKRRESKNFYSLSSSEPTILDVQFR
.||..|....|..| |. | ..|...||....|. .|. .|||.. .. | . .||..... . .. . . ||
SPKPRFCRVYFMDGTTLEFEVDSSTTGQDLCDHVCRHCGISPREHWYFGLWYEDPHEDRHWLDHWKTIMKQDVKW--------------HKSEPWTLHFR
VEFYVEN----VSVLSLAETRH-LYYLQLKRDVIQGTLATT-DQAAVQLSAFAMQAEYGDYDPT--------THVGRYFHVYDFFPEQTVVNMTVAI---
| ||... ...|.. ||. ..|||...|..|| . . .....|| |...|.|||||||. .|| |.. ..|.|.| .......
VKFYPPDWHGFPNQLQEDPTRYNYFYLQCRHDILQGRHPCPHEEECLQLAALQVQIEYGDYDPEETNNKKMTKHVQKYKSYKRFLPKQ--WIDSIKQSFM
--------LEREMPGQHRKLKDMSPVRAETEYLKLAQKLH-DYGVLYY
... .|.... |.| |. .||...|... ||| ..
HYQMHHKEWRKRIMEWHKNHCGMTPEEAKLKYLQICQRWPPMYGVEHF
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| FERM_M | 30339.AA | FERM_M | 243-358 | 19 | 9.9e-32 | 110.12 | Pfam | 1-171 (171) | Show / Hide |
Range on Protein: 243-358
Range on HMM: 1-171/171
Sequence Identity: 19% (34 aa)
NVSV-LSLAETRHLYYLQLKRDVIQGTLATTDQAAVQLSAFAMQAEYG-DYD-PTTHVGRYFHV--------------------YDFFP-----------
... .. . |||..|||.|.|...| . ... |..| | . |.|.| ||. |..| |. . ..|
DPNRDIQDEVTRHQFYLQAKWDILEGRYPCSEEEALMLAAYQCQIEFGSDYNPPQKHKSDYMEKEWWEQQEGMEVWLRCDNEQQERYWPAHCRLASKGRT
--------------------EQTVVNMTVAILEREMPGQHRKLKDM-SPVRAETEYLKLAQKLHDYGVLYY
. . |. . .|.... ||... | ||. |. .|....|.. .||| ..
MADSSYSEVSIRINPHCYVSPWYCKKMKQKQWEQRILEQHKNHRGMCSPEEAMLQYIQICQRWPMYGVHFF
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| KIND | 30339.AA | KIND | 4-176 | 16 | 6.9e-08 | 17.76 | SMART | 1-242 (242) | Show / Hide |
Range on Protein: 4-176
Range on HMM: 1-242/242
Sequence Identity: 16% (40 aa)
ISAHELLEQRGAPLEEAQLWAILGQALVALQDLDERD-------RLRLHINLSTLCLSDTGEVRFSESKQH-----AGA-ASFEAPERGSLAPTASSRAV
.| .|.||.||.|| | |.|| . |.. .|. .. . |. . .... ... |.| |.. || . ..| .|| . ... ..
VSLAEILECRGQPLNEEQAWAVCHQCCRSLRECPRQAHTCDPDYFHRVCCCWDLHLWREDGSVCFQPPEQHTPKEQRPDDRMFVPPEWDQCQSQTDHSDS
-------------------------------IHTHTYSLGVVLFFMADHNLPMNAEPS-------------PTWFASDSPVTTLLRFG-RL---------
| |.|| ||. .| ..| . |.. .. . .. . . .. ..
SSGDSSVINRAFDNSNHHHHHQHHHPPLVVSEKAHIYCLGMVLYWALDYHVPEHQECQLSQHLEQLIDRMCNDDHHDRCCDEHIEEYCEDWEDEDTEEER
---CFAEQSTRFV-KVHLLNGEVLMRPVHVDTFVRDVFRHVVNE
. ...| |. ||| . .. ..|. |..|. ....
YQVRSHHHSMRMCRAPHLLQRWHD--QNHYQAVCRAMFCETWEM
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| FERM_N | 30339.AA | FERM_N | 148-241 | 21 | 2.7e-05 | 21.93 | Pfam | 1-93 (93) | Show / Hide |
Range on Protein: 148-241 Range on HMM: 1-93/93 Sequence Identity: 21% (22 aa) VHLLNGEVLMRPVHVDTFVRDVFRHVVNEIGLHETAFFGLAL----MHT--REV-EFLDMERYVVSYFPTTPKRRESKNFYSLSSSEPTILDVQFRVEFY ||||....| . ..| ....|..|.. ... |. .|||. .. . .|| .... ... |. .. ...|..| ||| || VHLLDDTQLECTCDKKTTGQELFDQVCQHLNIRECWYFGLQFCKQNDKKEGNQHMHWLDPDKKICKQMKDGWKH------KIKKKCPPCTL--FFRVKFY V . P |
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| FERM_C | 30339.AA | FERM_C | 370-455 | 21 | 5.9e-07 | 27.14 | Pfam | 6-99 (99) | Show / Hide |
Range on Protein: 370-455 Range on HMM: 6-99/99 Sequence Identity: 21% (20 aa) P-LLIGINSRGIIIYEDLNDRKQN--PVKFAWSNIESLSLRNRKLTIMLK------GEGKQRHTVSADTQEKAAYLQHRCKAYHKFHFMMRQRYA . ...|....||..|. .|... . | |..|. .| . .|..| |. .... || ..... . || . | ..|.|. .|.. DTWWLGVCAKGINVYQV-QDNNKITPMNTFPWPEIRKISFKRKKFFIKLRDDPDEGEKYEHTHTFYMPNYRACKYLWKCCVEHHQFFRLRRPPDT |
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| PDZ | 30339.AA | PDZ | 862-930 | 31 | 1.3e-22 | 82.37 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 862-930 Range on HMM: 1-80/80 Sequence Identity: 31% (25 aa) EGLGLSIRGGGVVSDLRPDSAAARDGR-----IKRKDRILAVNG-KSLADLTHAEVIQLLRDTED-----VVNLTISPRS .|||.||.|| ..|.. |...|...|| .. ||||.||| ... ..||......|. . . .| ||. ... GGLGFSIVGGIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | 30339.AA | PDZ | 853-927 | 33 | 2.8e-22 | 78.9 | Pfam | 1-86 (86) | Show / Hide |
Range on Protein: 853-927 Range on HMM: 1-86/86 Sequence Identity: 33% (29 aa) NIRLEKR-PNEGLGLSIRG--------GGVVSDLRPD-SAAARDGRIKRKDRILAVNGKSLADLTHAEVIQLLRDTED-VVNLTIS ..|||. ..|||.||.| |...|.. |. .||.|.|||. |.|...||......||....|..... . .| ||| QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| PDZ | 30339.AA | PDZ | 995-1069 | 29 | 7.2e-19 | 69.92 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 995-1069 Range on HMM: 1-80/80 Sequence Identity: 29% (26 aa) TGLGFSITTKKKDPKSRILVGKVHAGTKADAAG------LAVGDHIVAVDG-RSLEGLTPTQALQVLSNTRS-----QVTLDIRPRA ||||||. |.. .| .|. |. || | .||.|..|.| ..|..| ||...| ... .||| .... GGLGFSIVG-------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | 30339.AA | PDZ | 986-1066 | 26 | 6.5e-14 | 50.24 | Pfam | 1-86 (86) | Show / Hide |
Range on Protein: 986-1066 Range on HMM: 1-86/86 Sequence Identity: 26% (23 aa) RVEIAKS-TKTGLGFSIT-TKKKDPKSRILVGKVHAGTKADAAG--LAVGDHIVAVDGRSLEGLTPTQALQVLSNTRS-QVTLDIR | . |. . |||||| ...... | . .| .| |...| . .|| |....|......| .| |.. .... .|.| |. QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| PDZ | 30339.AA | PDZ | 1239-1313 | 32 | 7.9e-19 | 69.8 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 1239-1313 Range on HMM: 1-80/80 Sequence Identity: 32% (28 aa) LGLGVVVAGGVDLGLGGIFVQEVRAQTPAAKAG------LQPSDRLLQIGD-VDFSGMTHAEALEALKQASN-----PILLRTQRVA |||. ..| |||. .| . .||.||| |.| ||.|.. . .. ..|||..|...|||... .. | || GGLGFSIVG-------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | 30339.AA | PDZ | 1231-1310 | 31 | 1.5e-15 | 55.87 | Pfam | 1-86 (86) | Show / Hide |
Range on Protein: 1231-1310 Range on HMM: 1-86/86 Sequence Identity: 31% (27 aa) IVSLHR--GRLGLGVVVAGGVDLG-LGGIFVQEVRAQTPAAKAG--LQPSDRLLQIGDVDFSGMTHAEALEALKQASN-PILLRTQ |.|.. .| |||. ..|| | . . ||.. || . .||..| ... |....|...|...|||..| .|.|.... .. | | QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| PDZ | 30339.AA | PDZ | 1368-1444 | 22 | 1.6e-12 | 48.81 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 1368-1444 Range on HMM: 1-80/80 Sequence Identity: 22% (20 aa) RGFGITIGGGADKTPPQPIRVEKIVTDSPAFHEGT-----IQVGDVILAANR-TPLDRSSYEHALNVLRSLPH-----ESTFCVLPKA |.|..| | .| . ..| ..|| . |. ...||.||. | .|.. ..| |...|.. . . |. |... GGLGFSIVG--------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | 30339.AA | PDZ | 1361-1441 | 23 | 2.9e-08 | 30.86 | Pfam | 1-86 (86) | Show / Hide |
Range on Protein: 1361-1441 Range on HMM: 1-86/86 Sequence Identity: 23% (20 aa) YVTLR---RSRGFGITIGGGADKTPPQPIRVEKIVTD-SPAFHEGTIQVGDVILAANRTPLDRSSYEHALNVLRSLPH-ESTFCVL ||| . |.|..| || |. . |.| . ... . ..| | |..||.|.. | ... . . | .... . | . .. QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| PDZ | 30339.AA | PDZ | 1746-1817 | 28 | 2.8e-16 | 61.31 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 1746-1817 Range on HMM: 1-80/80 Sequence Identity: 28% (24 aa) VTFGFSIAGGGDRPIYVKKVSPMTPAALGG------LSRHDVLLEVNG-HDVRLMDRPDLLKVIKEHKG-----QLRIRFIRPD .||||.| .|....| | .||. | | |..||||| .|. |. . ....|. .| .... .||. GGLGFSIVG----GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | 30339.AA | PDZ | 1748-1812 | 35 | 1.1e-10 | 39.21 | Pfam | 13-86 (86) | Show / Hide |
Range on Protein: 1748-1812 Range on HMM: 13-86/86 Sequence Identity: 35% (26 aa) FGFSIAGGGDR----PIYVKKVSPM-TPAALGG-LSRHDVLLEVNGHDVRLMDRPDLLKVIKEHKG---QLRIR .||||.||.| .||...|.|. .|. || . .|.....|| |.| | . ..||. || .| |. LGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| PDZ | 30339.AA | PDZ | 1985-2062 | 28 | 1.6e-17 | 65.43 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 1985-2062 Range on HMM: 1-80/80 Sequence Identity: 28% (25 aa) GGLGLRFQAQRDDTTGSQVVSIKEVCAGGAAERAGT-----LRAGDILVSVNG-QALAGKKPREIIDALSSASG-----LVRMRLVRRV ||||.. . . |..| .||.||.||. ||.||....||| | . .. ...|.| ...| |.. ..|. GGLGFSIVG---------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | 30339.AA | PDZ | 1976-2059 | 32 | 5.6e-14 | 50.45 | Pfam | 1-86 (86) | Show / Hide |
Range on Protein: 1976-2059 Range on HMM: 1-86/86 Sequence Identity: 32% (28 aa) DVVLDKT-QDGGLGLRFQAQRDDTTGSQVVSIKEVCAG-GAAERAGTLRAGDILVSVNGQALAGKKPREIIDALSSASG-LVRMRLV .|.| | . ||||.. . . |. | . |.|| .| |||||.| ...||...|.||| ... ....|. ...| |.. . QVTLEKQDKRGGLGFSIKGGNDQRH-DQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| PTPc | 30339.AA | PTPc | 2158-2430 | 26 | 4.8e-90 | 306.37 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 2158-2430 Range on HMM: 1-308/308 Sequence Identity: 26% (89 aa) QPADEYTELNNMRPQL---------TTRVGQSHMAA----NRYR-DILPCDETRVKLGAE----------GYINANLVQLPVAPGENRHQAILCQGPLPE . ..|. .| .|.|.. ....... . |||. ||...|.||||| . .||||| . . ..... |..|||||. GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY----WRPKRYICTQGPLPH TCADMWQMVWEQDTRVIVMVTSEKEK--------GHIKCHRYWPVRKRKKVTARNFTIENLGVVKKS-GFNVSTLQVHDSAS--------GASREVMHFQ |..| |.|||.| ...||| ... || | .|||.||| ..| ..|.... ..|.. .... |..| . . .|.|.|.. TIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYH FIDWPDHGVPSSAAQMVQMLREVALFQTSD-------------------AGPMAVHCSAGIGRSGVFVTLYTVLLALTLPLRALDVVAREHFEYTSIPVK . .|||||||.|. . ...|.| | . .||. ||||||.||.|.|... ... .. . .. YTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN-----------------VDIF EIVQKLREQRHPSVVQTSEQYLFVYKAYVTLLG .||...|.||. ||| |||.|.|.. .. QIVKMMRNQRPG-MVQTEEQYIFCYRCILEYIK |
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| Y_phosphatase | 30339.AA | Y_phosphatase | 2181-2427 | 33 | 5.4e-87 | 300.12 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 2181-2427 Range on HMM: 1-243/243 Sequence Identity: 33% (87 aa) HMAANRYRDILPCDETRVKL------GAEGYINANLVQLPVAPGENRHQAILCQGPLPETCADMWQMVWEQDTRVIVMVTSEKEKGH-IK-CHRYWPV-R .. |||.||...| ||||| . ||||| . |. | .. |..|||.|.|..| |.|||.| ...|||.... |.|. .| ||.||| NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG---PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNK KRKKVTARNFTIENLGVVKKSGFNVSTLQVHDSAS--GASREVMHFQFIDWPDHGVPSS-AAQMVQMLREVALFQT-SDAG--PMAVHCSAGIGRSGVFV . ..| .|.... . ......| |..| . . . .|.|.|.....|||||||.| . |....|.| .|. .|.| |. ||||||.||.|.|. EGQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFC TLYTVLLALTLPLRALDVVAREHFEYTSIPVKEIVQKLREQRHPSVVQTSEQYLFVYKAYVT .. ... .. ...||...|.||. ||| |||.|.|.. . AIDIMCQQMEHEGTV--------------DIFQIVKHMRNQRPG-MVQTEEQYIFCYQCILE |
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| PTPc_motif | 30339.AA | PTPc_motif | 2311-2427 | 28 | 1.3e-31 | 112.25 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 2311-2427 Range on HMM: 1-92/92 Sequence Identity: 28% (35 aa) EVMHFQFIDWPDH-----GVP-SSAAQMVQMLREVALFQTSDAGPMAVHCSAGIGRSGVFVTLYTVLLALTLPLRALDVVAREHFEYTSIPVKEIVQKLR .|.|... .|||| ||| .| ......|. |. ||||||.||.|.|....... . ....|...| TVHHYHYTNWPDHVEKDSGVPEDSILEFIRHVRK----------PIVVHCSAGCGRTGTFCAIDMMMQQ--------------------VDIFQTVKEMR EQRHPSVVQTSEQYLFVYKAYVT .|| | ||| |||.|.|.. KQR-PGMVQTEEQYIFCYRCILE |
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