Gene zak-1 (Nematode worm)

zak-1

Species: Nematode worm
Alias: R13F6.7, zak-1, R13F6.6, CE31722, aSWK420
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: ZAK

Sequence

Name Sequence Type Origin Length Description Download
zak-1.AA Protein None 745 None Fasta, JSON
zak-1.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of zak-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase zak-1.AA ZAK 31-287 71 4.90000000001e-230 770.49 In-house 1-257 (257) Show / Hide 
Range on Protein: 31-287
Range on HMM: 1-257/257
Sequence Identity: 71% (184 aa)

IQVGDHIGVGTFGAVFSGNWTLPDGSQRTIALKKVFVLEKEAEILSKIRHKNIIQFYGICKATGNDFFIVTEYAEKGSLYDFIHSEESQSFASSSGGNSF
||..||.||||||.|...||...|||||.||.||||..||||||||||||.||||||||||...||.||||||||||||||.|||..||...|||||||.
IQFFDHCGVGTFGSVYRANWISQDGSQREIAVKKVFKIEKEAEILSKIRHRNIIQFYGICKEPPNDYFIVTEYAEKGSLYDYIHSNRSQEMDSSSGGNSM

DVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDLTHSCTAPSWGGTAAWMSPEMILQSEGLTTATDVWSYGVVLWEILSK
|...|||.|||.|..|||.||.|.||||||||.|||.|||.||||||||||.|..|.||..||.||..||.||||||||..|...|||||||||||.|..
DHIMKWATQIAKGMHYLHMDAPDKIIHRDLKSRNVVIDKNGVCKICDFGTSRDFHHHCTHMSWVGTFPWMAPEMILQSEPVTETCDVWSYGVVLWEMLTR

EVPYKDYSEFRIFTMITQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGE
|||||||.||.||.||.|..|.|.||||||.|.||||..||||.||||.||||||..
EVPYKDYEEFQIFWMIVQKNIRLTIPPSCPRPFKQLMHQCWKMDPKDRPNMRQIQSI
Kinase zak-1.AA MLK 31-288 38 5.6e-135 454.72 In-house 1-291 (291) Show / Hide 
Range on Protein: 31-288
Range on HMM: 1-291/291
Sequence Identity: 38% (113 aa)

IQVGDHIGVGTFGAVFSGNWTLPDGSQRTIALKKVF--------------VLEKEAEILSKIRHKN----IIQFYGICKATGNDFFIVTEYAEKGSLYDF
||.  .||.|.||.|..|.|   |......|.|.|.               .|.|...|....|.|    ||||||.|. ....|.||.||.|.||||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

IHSEESQSFAS-----SSGGNSFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLD------KNLVCKICDFGTSKDLTHSCT-APSWGGTAAWM
.|...|.....     ...  ..|....|| |.|.|..|||..|...||||||||.|...|      .....||||||||.|....||  .|. ||.|||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

SPEMI--LQSEGLTTATDVWSYGVVLWEILSKEVPYK-DYSEFRIFTMITQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGEL
.||.|  ...|  . . ||||.||||||.|..||||| .|....|. .... |....||..||...|.||..||.. |..| ..|||. .|
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase zak-1.AA TKL 37-288 25 9.1e-92 311.17 In-house 1-364 (364) Show / Hide 
Range on Protein: 37-288
Range on HMM: 1-364/364
Sequence Identity: 25% (98 aa)

IGVGTFGAVFSGNWTLPDGSQ------RTIALKKVFV-----------------------------------LEKEAEILSKIRHKNIIQFYGICKATGN
|| |.|| |. |.|   .| .      ...| ||  .                                   .|.|. ..|..|| ||.||.|.|.. ..
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

D------------FFIVTEYAEKGSLYDFIHSEESQSFASSSGGNSFDVVVKWASQIASGIQYLHYDAV-----DTIIHRDLKSKNVVLDKNLV------
.            ..||.||...|||....|               ... ..|| .||.|..||| .         ||||||||||. .|.|.       
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYM

--------CKICDFGTSKDLTHSC--------------------TAPSWGGTAAWMSPEMILQS---------------EGLTTATDVWSYGVVLWEILS
        |||||||.|.....|                     |  . .|| .||.||.. ..               .  ....||.|.|.||||||.
YNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILT

KEVPYKDYSEF---------RIFTMITQSGITLAIP------------PSCPAPLKQLMSNCWKMTPKDRANMRQIQGEL
 ..||.|| ..          .| |. . |  . ||            |.|| ..|.||  ||.. |..| .. .|  .|
RCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase zak-1.AA Pkinase_Tyr 31-288 29 1.2e-62 212.77 Pfam 1-270 (270) Show / Hide 
Range on Protein: 31-288
Range on HMM: 1-270/270
Sequence Identity: 29% (84 aa)

IQVGDHIGVGTFGAVFSGNWT-LPDGSQRTIALKKV-----FV------LEKEAEILSKI-RHKNIIQFYGICKATGND--FFIVTEYAEKGSLYDFIHS
|. |  .| | || |. | |. .||. . . | |..             . .||.|.... .|.||...||.|   |     .||.||...|.|.|. ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

EESQSFASSSGGNSFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDL-------THSCTAPSWGGTAAWMSPEMILQS
       .. .  .    .... |||.| .||.      .|||||  .|. ...|.|.|||||| ..|.       . .  ..       ||.|| |  .
HR-----EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK---LPIKWMAPECINYG

EGLTTATDVWSYGVVLWEILSKE-VP-YKDYSEFRIFTMITQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGEL
.  ||..||||.||..|||..    | |.. | .... .|...|  ...|. ||... .||  ||.  |.||  ...|. .|
K-FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase zak-1.AA LZK 31-288 38 2.8e-59 198.5 In-house 1-241 (241) Show / Hide 
Range on Protein: 31-288
Range on HMM: 1-241/241
Sequence Identity: 38% (101 aa)

IQVGDHIGVGTFGAVFSGNWTLPDGSQRTIALKKVFVLEKEAEI--LSKIRHKNIIQFYGICKATGNDFFIVTEYAEKGSLYDFIHSEESQSFASSSGGN
|.  . .| |  ||||.| .       .|.| |||  | || .|  | | .|.|||.| |.|      . |. ||  .| ||.   ..            
ISELQWLGSGAQGAVFRGWFR-----NETVAVKKVRDL-KETDIKHLRKLKHPNIIEFKGVCTQSPC-YCIIMEYCPHGQLYEVLRERRTITPQ------

SFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDLTHS-CTAPSWGGTAAWMSPEMILQSEGLTTATDVWSYGVVLWEI
     | |  |||.| .|||      |||||||| |.   .| | ||||||||. .     |  |  || ||| ||.| . |      |.||.||||||.
---LMVDWSKQIAQGMHYLH---QHKIIHRDLKSPNILISHNDVVKICDFGTSHMWNEMDSTKMSFCGTVAWMAPEVI-RNEPCSEKVDIWSFGVVLWEM

LSKEVPYKDYSEFRIFTMITQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGEL
|  |.||||     |   .      | .| .||  .| ||  ||.  |  |   |||   .
LTCEIPYKDVDSMAIIWGVGSNSLHLPMPSTCPEGFKLLMKQCWSQKPRNRPSFRQILMHW
Kinase zak-1.AA TKL-Unique 33-288 27 1.1e-56 194.69 In-house 1-290 (290) Show / Hide 
Range on Protein: 33-288
Range on HMM: 1-290/290
Sequence Identity: 27% (81 aa)

VGDHIGVGTFGAVFSGNW-----TLPDGS-QRTIALKKVFVLEKEAEILSKIR-HKNIIQFYGICK---ATGNDFFIVTEYAEKGSLYDFIH-SEESQSF
..  || |..|.|. | |     ..   . .  . ..... .|.|  ...|.. |.|| ...|.|.    . ....||.|| . ||||| .| .      
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

ASSSGGNSFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDKN-----LVCKICDFGTSKDLTHSCTAPSWG----------GTAAWMSPEMIL
 ...  ... ..|| | .||.|  |||      ||||||||.|. .| |     .  ||||||.|| .. . . .. .          |.. ||.||.. 
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

QS-EGLTTATDVWSYGVVLWEILSKEV------PYKDYSEFRIFTMITQ--SGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGEL
.. .  ..  ||.|.|.|||||.. ..      ||....   .. |...   .  . ||..||  .. |.  ||.  | .| .  .|  .|
MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase zak-1.AA Pkinase 31-288 23 1.6e-56 198.89 Pfam 1-293 (293) Show / Hide 
Range on Protein: 31-288
Range on HMM: 1-293/293
Sequence Identity: 23% (72 aa)

IQVGDHIGVGTFGAVFSGNWTLPDGSQRTIALKKVFVLEK------------EAEILSKIRHKNIIQFYGICKATGNDFFIVTEYAEKG----SLYDFIH
...|  || |.|| |. . .    |.... |.|.. . ..            |..|. ...|.||...|...   ...  .|.||.|.|    .|.|.|.
YHIGRKIGSGSFGCVYKCHH---KGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

SEESQSFASSSGGN--SFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDKNLVC----KICDFGTSKD--LTHSCTAPSWGGTAAWMSPEMIL
        ...|.   | ... ... ||..|..|.|      |||||||. |. .|.| ..    |||||| .|   . ..  . .  ||  .|.|| |.
T-------WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR

QSEGLTTATDVWSYGVVLWEILSKEVPYKDY------SEFRIFTMITQSGITLAIPPSCP-------------------APLKQLMSNCWKMTPKDRANM
 ... ... |.||.|..|.| |... |...       ..  .. .| .  .   .| .|.                    ..|.....|... ||.| . 
GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA

RQIQGE--L
.||     .
EQILQHPWF
Kinase zak-1.AA TK 31-288 16 2.9e-54 179.92 In-house 1-486 (486) Show / Hide 
Range on Protein: 31-288
Range on HMM: 1-486/486
Sequence Identity: 16% (80 aa)

IQVGDHIGVGTFG---AVFSGNWTLPDG------------------------SQRTIALKKVF--VLEK------------------EAEILSKIR----
|..|. .| | ||    |. | |  ...                         .  .. .|      ..                  |||.... .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNIIQFYGICKATGND-----------FFIVTEYAEKGS----LYDFIHS-EESQSFASSSGGNSFDVVVK---------------------------
 |.||...||.|   ..            . ||.||...|.    | |. ..  .  .  .....|. . ..                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------WASQIASGIQYLHYDAVDTI----IHRDLKSKNVVLDKNLV-----------CKICDFG---
                                      .. |||.| .|||   .       .||||   |. ...|.|           |||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----TSKDLTH-----SCTAPSWGGTAAW-----------------------MSPEMILQSEG--------LTTATDVWSYGVVLWEILS--KEVPYKD
      ..|. .     . . .. |. . |                       |.|| ..  .          ||..||||.||..|||..  .| .| .
QGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

YSE---------FRIFTMITQS-------------GITLAIPPSCP--------------APLKQLMSNCWKMTPKDRANMRQIQGEL
 |            .. ....              .  .. || ||              . . .||  ||.  |.|| ...|.. .|
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase zak-1.AA TyrKc 31-288 27 1.1e-53 185.54 SMART 1-280 (280) Show / Hide 
Range on Protein: 31-288
Range on HMM: 1-280/280
Sequence Identity: 27% (83 aa)

IQVGDHIGVGTFGAVFSGNWTLPDGSQRTIALKKVF-----VLEKEAEILSKI--RHKNIIQFYGICKATG------NDFFIVTEYAEKGSLYDFIHSEE
|. |. .| | || |. | |.      .. | |..       . .||.|..|.  .|.||...||.|   |         .||.||...|.| |.... .
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

SQSFASSSGGNSFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDLTHS---------CTA----PSWG-GTAAWMSPE
 .         . .  .... |||.| .|||      .|||||   |. ...|...||.||| |.|...           ..     . .     ||.||
PK--------LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

MILQSEG-LTTATDVWSYGVVLWEILSK-EVPYKD-----YSEFRIFTMITQSGITLAIPPS--------CPAPLKQLMSNCWKMTPKDRANMRQIQGEL
 |   .|  ||..||||.||..|||..  . || .      | ....  . ..|  . .||.        ||. . |.|. ||.  |.|| ....|  ..
CI--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV-KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase zak-1.AA Dicty4 70-290 34 3.6e-52 172.37 In-house 47-277 (277) Show / Hide 
Range on Protein: 70-290
Range on HMM: 47-277/277
Sequence Identity: 34% (82 aa)

KEAEILSKIRHKNIIQFYGICKA---TGNDFFIVTEYAEKGSLYDFIHS---EESQSFASSSGGNSFDVVVK---WASQIASGIQYLHY-DAVDTIIHRD
||..|..|||| ||..|.| | |   .  .. |||||  ||.||  .|.   |  ||  ..     .  . .    |  .| |...||  . |  |||||
KEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLD-----WPLIKRAMRMAFDAARGMNWLHCCNPV--IIHRD

LKSKNVVLDKNLVCKICDFGTSK----DLTHSCTAPSWGGTAAWMSPEMILQSEGLTTATDVWSYGVVLWEILSKEVPYK-DYSEFRIFTM-ITQSGITL
||| |   |||.. |.|||| |.    . .|.  . .  ||..||.||. ..... . . || |.| |||||| .. ||   .... .|   . . .  .
LKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEV-MMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRP

AIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGE--LNR
 ||..||...|.|.  ||   |. |  . .|  .  |. 
PIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase zak-1.AA MLK 68-288 32 4.9e-52 170.18 In-house 48-280 (280) Show / Hide 
Range on Protein: 68-288
Range on HMM: 48-280/280
Sequence Identity: 32% (81 aa)

LEKEAEILSKIRHKNIIQFYGICKATGNDFFIVTEYAEKGSLYDFIHSEESQSFASSSGGNSFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVL
. .|| ..  ..| |||.  |.|    . . .| ||.. |||   .                 .| | || ||| | .||| .|.  ||||||||.|. .
VRQEARLFWMLKHPNIIALRGVCLEDPH-LCLVMEYCRGGSLNRVCAGK----------RIPPHVLVNWAVQIARGMNYLHNEAPVPIIHRDLKSSNILI

DKNLVC--------------------------KICDFGTSKDLTHSCTAPSWGGTAAWMSPEMILQSEGLTTATDVWSYGVVLWEILSKEVPYKDYSEFR
 .. .|                          || |||   ....     |  || ||| || | .|     . |||||||.||| |  ||||. .    
-LEKICLCMDEEMFQYAYCLKCGHHDMCNKQLKITDFGLAREWHKTT-RMSAAGTYAWMAPEVIKEST-WSKGSDVWSYGVLLWELLTGEVPYRGIDPLA

IFTMITQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGEL
.   .   . || || .|| | ..|| .||.  |  | .  .|  .|
VAYGVAMNKLTLPIPSTCPEPWAKLMQDCWNQDPHKRPKFSEILQQL
Kinase zak-1.AA TK-Unique 31-288 27 6.9e-50 170.21 In-house 1-294 (294) Show / Hide 
Range on Protein: 31-288
Range on HMM: 1-294/294
Sequence Identity: 27% (82 aa)

IQVGDHIGVGTFGAVFSGNWTLPD---GSQRTIALKKVF----VLE-----KEAEILSKIR-HKNIIQFYGICKATGNDFFIVTEYAEKGSLYDFIHSEE
. ||| || | || |. |  . ..   . |. .|.|..      ..     ||.......  |.||.|..|.|  ......|. ||...|.| .....  
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

SQSFAS-----------SSGGNSFDVVVK------WASQIASGIQYLHY--DAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDLTH----SCTAPSWG
 . . .           .     ..  ..      .| |||.| .||.   . .   .|||| ..|| |  ..|||||||| ..|. .    | .  .  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI---VHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGR

GTAAWMSPEMIL--QSEGLTTATDVWSYGVVLWEILS--KEVPYKDYSEFRIFTMITQSGITLAIPPSC-PAPLKQLMSNCWKMTPKDRANMRQIQGEL
   .||.|| ..  .    || .||||.||..|||..  .  || ...  .| ..|.. | ..  |..| .  . .||..||.  |..| . |||  .|
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGA-CPYPGMPWKDIMECIRD-GYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase zak-1.AA TAK1 31-287 26 3.3e-49 164.35 In-house 1-284 (284) Show / Hide 
Range on Protein: 31-287
Range on HMM: 1-284/284
Sequence Identity: 26% (79 aa)

IQVGDHIGVGTFGAVFSGNWTLPDGSQRTIALKKVFVL------------EKEAEILSKIRHKNIIQFYGICKATGNDFFIVTEYAEKGSLYDFIHS-EE
||.   .| ||.|.|    |       . ||.|. . .            |.|   .|.. | |||. ||. . ...    | ||.. |||..|.|. . 
IQNEHFVGKGTYGVVCKAKWR-----NKEIAVKRFEFIKYSSEECEQKNIEREIMQWSRVDHPNIIKLYGMYACHRQCQCLVMEYMDCGSLHNFLHGAKP

SQSFASSSGGNSFDVVVKWASQIASGIQYLHYDAVD--TIIHRDLKSKNVVL-DKNLVCKICDFGTSKDLTHSCTAPSWGGTAAWMSPEM----------
  .        . . .. |. |.|.|. |||  . .   .||||.|  |  | .| .. |||||||  |.  . |  .  ||..|| ||           
KWEY-------THAHAMSWMHQCAQGVAYLH--SMQPKPQIHRDIKPQNMLLCNKHRTLKICDFGTFCDMHQMMT--CNRGTCRWMAPEVRELFDFKSNR

-----------ILQSEGLTTATDVWSYGVVLWEILSKEVPYKDYSE----FRIFTMITQSGI--TLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGE
           ... |  .   |. |.|...||..|   ||...      .||   | .      ..    || ...|.|  ||.  | .|  |  .   
IIINQPTGFQKVFRCEKYNMKCDIYSWGIIMWEVISRKHPYDHIMNPNSAYRIMWAIHNGNRPPMETNRSDCPKRIEQFMKCCWDDNPEKRPSMQECVKY
Kinase zak-1.AA S_TKc 31-292 24 7.5e-47 162.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 31-292
Range on HMM: 1-231/231
Sequence Identity: 24% (66 aa)

IQVGDHIGVGTFGAVFSGNWTLPDGSQRTIALKKVF-VLEKEAEILSKIRHKNIIQFYGICKATGNDFFIVTEYAEK--GSLYDFIHSEES----QSFAS
 .....|| |.|| |. . ..    ..|  |.|..   ...| .||.| .|.||...|...    .....|.||..   |.|.|.|..  .    . |  
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF--

SSGGNSFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDLTHSCTAPSWGGTAAWMSPEMILQSEGLTT-ATDVWSYGV
     .  .. ... ||.....|.|      |||||||  |. ||.  . |||||| .. |       .  ||  .|.||..    | .. . |.|| |.
-----PE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGC

VLWEILSKEVPYKDYSEFRIFTMITQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQG-----ELNRLA
.|.| |. . |.    ....| .|             . ..|.....|... |..|    ..        .    
ILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase zak-1.AA Dicty4 31-50 45 0.000114 11.69 In-house 1-20 (277) Show / Hide 
Range on Protein: 31-50
Range on HMM: 1-20/277
Sequence Identity: 45% (9 aa)

IQVGDHIGVGTFGAVFSGNW
|.... || | || |. |.|
INIEQRIGKGSFGEVYKGTW
Kinase zak-1.AA MLK 31-50 35 0.031622 2.9 In-house 1-20 (280) Show / Hide 
Range on Protein: 31-50
Range on HMM: 1-20/280
Sequence Identity: 35% (7 aa)

IQVGDHIGVGTFGAVFSGNW
... . ||.| || |. . |
LKIKEIIGNGGFGKVYRAQW
SAM zak-1.AA SAM 371-438 23 1.5e-08 35.67 SMART 1-67 (67) Show / Hide 
Range on Protein: 371-438
Range on HMM: 1-67/67
Sequence Identity: 23% (16 aa)

TSHWVETVLGRVANDKKFLDRVNAAVFRNRITGARLLGMT-QNDLEHLGVHKVGSRIELMKMIRKLADT
 . | .  ...     .. . .  .  .|.|.|. || .| ..||...|....| |  ..| |.|. |.
VD-WTPEDVCDWLESIGMCQ-YKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
Sam7 zak-1.AA sam7 366-436 18 2.3e-08 27.68 In-house 1-70 (70) Show / Hide 
Range on Protein: 366-436
Range on HMM: 1-70/70
Sequence Identity: 18% (14 aa)

WSEHHTSHWVETVLGRVANDKKFLDRVNAAVFRNRI-----TGARLLGMTQNDLEHLGVHKVGSRIELMKMIRKLA
|.... . |.| .  .      ....   .  ...|     .|. |. ||..||...|....| |  ... |... 
WTFEDVCEWLEWIGME------NFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM_2 zak-1.AA SAM_2 398-436 29 3.3e-05 20.73 Pfam 28-71 (71) Show / Hide 
Range on Protein: 398-436
Range on HMM: 28-71/71
Sequence Identity: 29% (13 aa)

RNRITG-ARL-LGMTQNDL--E-HLGVHKVGSRIELMKMIRKLA
.. |||   | ..||..||  . ..|...|| | .... | .. 
QHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK