Gene n434 (Tetrahymena)

n434

Species: Tetrahymena
Alias: 3708.m00124, 434, n434
External Links:
Annotation:

Classification

Group: Other
Family: Ciliate-E8

Sequence

Name Sequence Type Origin Length Description Download
n434.AA Protein None 861 None Fasta, JSON
n434.NA RNA None 2586 None Fasta, JSON
n434.kin_dom Protein Kinase Domain None 58 None Fasta, JSON

Protein domain

Protein domains of n434.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase n434.AA Ciliate-E8 456-514 62 2.7e-36 110.87 In-house 29-92 (138) Show / Hide 
Range on Protein: 456-514
Range on HMM: 29-92/138
Sequence Identity: 62% (40 aa)

KFQQLNEACIQMLLCHPNIQNIEEVFVDKSNEIVIVQKMQGENLNKLLIDKKID-----QEKAM
||  |||.|||||.||.|||||..|.    |.||||||||||||.|.|. ||||     |.|.|
KFDILNEICIQMLVCHRNIQNIYDVYQNENNKIVIVQKMQGENLRKYLKFKKIDGSYICQNKRM
Kinase n434.AA Ciliate-E8 516-539 70 1.3e-15 45.24 In-house 115-138 (138) Show / Hide 
Range on Protein: 516-539
Range on HMM: 115-138/138
Sequence Identity: 70% (17 aa)

FKLENVVIVLDDDTKIKIIDFGFS
|||.|......|||||||||||||
FKLNNILVQRNDDTKIKIIDFGFS
Kinase n434.AA Ciliate-E2 517-574 22 2.6e-11 35.06 In-house 188-283 (365) Show / Hide 
Range on Protein: 517-574
Range on HMM: 188-283/365
Sequence Identity: 22% (23 aa)

KLENVVIVLDDDTKIKIIDFGFSQIKIFN----------KFFTPLGS-----------------------TKGYAPP----EKK---------YTFESDI
|.||...       |||||||.|..   .          | ..  ..                       | || .|     ||         |....||
KPENILF-------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDI

FSIG
.|.|
WSLG
S_TKc n434.AA S_TKc 419-669 16 2.7e-08 -55.35 SMART 1-231 (231) Show / Hide 
Range on Protein: 419-669
Range on HMM: 1-231/231
Sequence Identity: 16% (47 aa)

YNFCSQFRETGLNKLFKYQKGN--EQFVIKKKKETNQQQKFQQLNEACIQMLLCHPNIQNIEEVFVDKSNEIVIVQKMQG--ENLNKLLIDKK-------
| .  .  . .  | .| .. .  ... ||. |        . ..|  | .   |||| .. .||.| ..  ..   . |   .| ... ...       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

IDQEKAMNF---------------------KLENVVIVLDDDTKIKIIDFGFSQIKIFNKFFTPLGSTKGYAPPEK-KYTF-ESDIFSIGESIKKIRFHY
..   |  .                     | ||. .       |||.|||.. .       | .  |  | .||  .|.. ..|. |.|  .      |
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGY

NTFSVEQETENEKTKFKEFQNKYQQFEIIGIIKSIKLLLDAKINTLNQSFVECLVDNDIKLFILKLLNFEKM----ICQEQN----NSIDPQI
  |.                . .. |..||                         . . | || |.|...      . .  .      ..| .
PPFP----------------QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase n434.AA CAMK 517-574 18 7.1e-08 20.7 In-house 206-321 (425) Show / Hide 
Range on Protein: 517-574
Range on HMM: 206-321/425
Sequence Identity: 18% (22 aa)

KLENVVIVLDDD---------------TKIKIIDFGFSQIKIFNK-------------------------FFTPLGSTKGYAP-PE--KK----------
|.||. .. ..|                .||||||||..... ..                         . |. | | .|.. ||  ..          
KPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCG-TPEYMAAPEVLNGKGHCNMQNAT

------YTFESDIFSIG
      |....|. |.|
DEEKPYYGPKCDMWSCG
Kinase n434.AA Ciliate-E2a 517-574 27 2.6e-07 17.59 In-house 129-203 (275) Show / Hide 
Range on Protein: 517-574
Range on HMM: 129-203/275
Sequence Identity: 27% (21 aa)

KLENVVIV-LDDD----TKIKIIDFGFSQIK---IFNKFFTPLGSTKGYAP------PE----KKYTFESDIFSIG
|.||. .  .. .    ..|||||||...     . .. |.  | | || .      .|    |.|.   |..|.|
KPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCG-TPGYVAPEVLNNKEVLKHKQYDTKCDMWSCG
Kinase n434.AA Ciliate-E2-Unclassified 523-574 26 8e-06 16.3 In-house 175-257 (352) Show / Hide 
Range on Protein: 523-574
Range on HMM: 175-257/352
Sequence Identity: 26% (22 aa)

IVLDDDT---KIKIIDFGFSQ-----------------IKIFNKFFTPLGSTKGYA----PPE----KKYT----FESDIFSIG
|..|..    .|||||||.|                  | ..... |  | | .|     .||    ..|     ...||.| |
ILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCG-TPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLG
Kinase n434.AA Pkinase 517-574 27 2.1e-05 20.16 Pfam 135-199 (293) Show / Hide 
Range on Protein: 517-574
Range on HMM: 135-199/293
Sequence Identity: 27% (19 aa)

KLENVVIVLDDDTK---IKIIDFGFSQI--KIFNKFFTPLGSTKGYAPPE-----KKYTFESDIFSIG
|.||. |. ....    .||.|||..       |  .| .  | .|..||     ..|. ..|..|.|
KPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG
Kinase n434.AA MSK 517-561 34 3.3e-05 13.55 In-house 128-175 (277) Show / Hide 
Range on Protein: 517-561
Range on HMM: 128-175/277
Sequence Identity: 34% (18 aa)

KLENVVIVLDDD---TKIKIIDFGFSQIKIFNKF-FTPLGS---TKGYAPPE
|.||  | .||.    ..|.|||||.  ..|...   .. |   |  |..||
KPEN--ILFDDEEDNGHVKLIDFGFA--RLFPQDEEWRMKSPCFTLHYMAPE
Kinase n434.AA NuaK 517-539 56 3.6e-05 8.97 In-house 126-146 (252) Show / Hide 
Range on Protein: 517-539
Range on HMM: 126-146/252
Sequence Identity: 56% (13 aa)

KLENVVIVLDDDTKIKIIDFGFS
||||  | ||..  .|| ||| |
KLEN--ILLDQNCNAKIADFGLS
Kinase n434.AA MARK 517-539 56 4.6e-05 12.7 In-house 131-153 (262) Show / Hide 
Range on Protein: 517-539
Range on HMM: 131-153/262
Sequence Identity: 56% (14 aa)

KLENVVIVLDDDT--KIKIIDFGFS
|.||  | .|...  .|||||||||
KPEN--ILIDENGNHNIKIIDFGFS
Kinase n434.AA Ciliate-B2 535-574 39 6e-05 7.46 In-house 147-197 (197) Show / Hide 
Range on Protein: 535-574
Range on HMM: 147-197/197
Sequence Identity: 39% (20 aa)

DFGFSQIKIFNKFFTPLGSTKGYAPPE-----------KKYTFESDIFSIG
||| | ||  |      | || ||.||            .  | |||.|.|
DFGISSIKKDNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase n434.AA CAMKL 517-539 52 7e-05 11.35 In-house 154-176 (297) Show / Hide 
Range on Protein: 517-539
Range on HMM: 154-176/297
Sequence Identity: 52% (12 aa)

KLENVVIVLDDDTKIKIIDFGFS
|.||. .  ... .|||||||||
KPENILLDENGNNNIKIIDFGFS
Kinase n434.AA CAMK 444-491 15 0.000264 8.99 In-house 38-135 (425) Show / Hide 
Range on Protein: 444-491
Range on HMM: 38-135/425
Sequence Identity: 15% (15 aa)

VIKKKKETN------------------------QQQKFQQ-LNEACIQML-------LCHPNIQNIEEVFVDKSN------------------EIVIV
.|.||| ..                        .... .. ..| .| ..       | |||| .. ||. |...                  ....|
IIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMV
Kinase n434.AA CAMKL 444-491 23 0.00148 7.05 In-house 32-99 (297) Show / Hide 
Range on Protein: 444-491
Range on HMM: 32-99/297
Sequence Identity: 23% (16 aa)

VIKKKKET-NQQQKFQQLN-----------EACIQMLLC---HPNIQNIEEVFVDKSN-----EIVIV
.|.||| . ... |   ..           |..|...|    ||||  . ||. ....     .|..|
IIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV
Pkinase n434.AA Pkinase 435-492 22 0.770795 4.05 Pfam 19-79 (293) Show / Hide 
Range on Protein: 435-492
Range on HMM: 19-79/293
Sequence Identity: 22% (14 aa)

KYQKGNEQFVIKKKKETNQQQKFQQLN----EACIQMLLCHPNIQNIEEVFVDKSNEIVIVQ
. .. ......|. |  ..  ...| .    |..|   |.||||  . ..| | ...| .|.
HHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVM