Gene n486 (Tetrahymena)
n486
Species: Tetrahymena
Alias: 486, 3702.m00229, n486
External Links:
Annotation:
Sequence
Protein domains of n486.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | n486.AA | NEK | 18-274 | 40 | 4.5e-136 | 458.36 | In-house | 1-286 (286) | Show / Hide |
Range on Protein: 18-274 Range on HMM: 1-286/286 Sequence Identity: 40% (117 aa) YEKVKLLGSGNQGKAYLCKHAQTNQQ-----FVIKQIQLSCMSDQEIQKQY-KEVSILKSLSHPNIIKYQDSFLFKK-NYLCIVMDYAE-GGDLEQR--- ||..| .|.|..||.|.... ..... .|.|.|....||..| |. . .|| |||.| ||||.|| |||. .. |.|||||.|.| ||||.|. YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS IIQAQKANTLFDCKTILKWFTQLCSAVRFIHNQ-----KIIHRDIKNSNIFLDSNDN----ILLGDFGISKKLQNPKDKAST-IIGTPYFMAPEICNQQP | . ......|. ..|..||.|.|.|....|.. ||.||||| .||||..|.| . .||||||| |.. .|.|.| .||||.|.||.|...| IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP YTNKVDIWAIGIVLFRLVYL--KYPFEGF--EIFHLMLAISRG-QLK-FPQT--PSSPLKNLIQKLLQNDPNKRPSIEQVFGKRIY |.||.|||..| ||. .. | | |||. . .|.. | .| | . |.. |. |.|||...|| || .|||..|.. . . YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI |
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| Kinase | n486.AA | NEK1 | 18-274 | 39 | 2.5e-103 | 349.58 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 18-274 Range on HMM: 1-276/276 Sequence Identity: 39% (109 aa) YEKVKLLGSGNQGKAYLCKHAQTNQQFVIKQIQLSCMSDQEIQKQYKEVSILKSLSHPNIIKYQDSFLFKKN-YLCIVMDYAEGGDLEQRIIQAQKANTL |.. | .|.|. |||.| || .|..||| |....|...|... .|| ||. . ||||.||..|| . | |||.|..|||| |.| .. . | YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL FDCKTILKWFTQLCSAVRFIHNQKIIHRDIKNSNIFLD--SND---------------NILLGDFGISKKLQNPKDKASTIIGTPYFMAPEICNQQPYTN | .|. ||.|.| |. .|| .||.||||| .|||| .|. . ||||||.. |... . |.| ||||| ||||. .||.| FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN KVDIWAIGIVLFRLVYLKYPFEGFEIFHLMLAISRGQL-KFPQTPSSPLKNLIQKLLQNDPNKRPSIEQVFGKRIY | |||. | || |. || |||. .| | | .| . |...| |..|. .... .| |||. |. . . KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI |
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| Kinase | n486.AA | S_TKc | 18-275 | 30 | 1.2e-84 | 288.4 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 18-275 Range on HMM: 1-231/231 Sequence Identity: 30% (82 aa) YEKVKLLGSGNQGKAYLCKHAQTNQQFVIKQIQLSCMSDQEIQKQYKEVSILKSLSHPNIIKYQDSFLFKKNYLCIVMDYAEG--GDLEQRIIQAQK--A ||.....|.| || |.|.| |.... ||.| .. ..|..|||. ||||.|. |.| ..|..||.|..| ||| ..| . .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGL NTLFDCKTILKWFTQLCSAVRFIHNQKIIHRDIKNSNIFLDSNDNILLGDFGISKKLQNPKDKASTIIGTPYFMAPEICNQQPYTN-KVDIWAIGIVLFR . |. .. ... |.|.|. ..|...|||||.| .||.||. .| ..|||....| .|..|||..||||.. .|. |.|.|..|..|. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE LVYLKYPFEGFEIFHLMLAISRGQLKFPQTPSSPLKNLIQKLLQNDPNKRPSIEQVFG------KRIYF ... . ||. ... .. | |...|..|.|.|| ||.|||.. ... . .| MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | n486.AA | NEK8 | 18-268 | 35 | 9.8e-82 | 233.11 | In-house | 1-272 (278) | Show / Hide |
Range on Protein: 18-268 Range on HMM: 1-272/278 Sequence Identity: 35% (97 aa) YEKVKLLGSGNQGKAYLCKHAQTN--QQFVIKQIQLSCMSDQEIQKQYKEVSILKSLSHPNIIKYQDSFLFKKNYLCIVMDYAEGGDLEQRIIQAQKANT ||.. .| | | . |. . .. ..||| .. || | | |...|. | ||||| | |.|. . | | |.| ||.|| |.| .|| |.. YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFM-EDNTLMIEMEYADGGTLYQ-MIQHQQNKL LFDCK----------------TILKWFTQLCSAVRFIHNQKIIHRDIKNSNIFLDSN-DNILLGDFGISKKLQNPKDKAST---IIGTPYFMAPEICNQQ ... . .|| |.| ||||...| | |||.| |||.. . .|||||||.. | | ...| ..|||| | ||.| . FEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIM-NTKYHMQTTKTVVGTPYYMSPEMCEGK PYTNKVDIWAIGIVLFRLVYLKYPFEGFEIFHLMLAISRG--QLKFPQTPSSPLKNLIQKLLQNDPNKRPSIEQV || .| |.||.| ||. . || ||. | . | .. . . |. .. |. .|| || .||| |. PYNQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQI |
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| Kinase | n486.AA | Pkinase | 18-275 | 27 | 3.2e-80 | 277.62 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 18-275 Range on HMM: 1-293/293 Sequence Identity: 27% (83 aa) YEKVKLLGSGNQGKAYLCKHAQTNQQFVIKQIQLSCMSDQEIQKQYK--EVSILKSLSHPNIIKYQDSFLFKKNYLCIVMDYAEGG----DLEQRII-QA |.... .|||. |. |.|.| |......|.| .. .... | . |..|.|.|.||||... |.| |.....||.|.||| || .| .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR QKANTLFDCKTILKWFTQLCSAVRFIHNQKIIHRDIKNSNIFLDSNDNI----LLGDFGISKKL-QNPKDKASTIIGTPYFMAPEICN-QQPYTNKVDIW ... . |. ... ....|..... ..|...|||||.| .||..|.|..| ..|||..|.. .. ..|. |||..||||... .|.|. |||.| HGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW AIGIVLFRLVYLKYPFEGF------EIFHLMLAISRGQLKFPQTPS---------------------SPLKNLIQKLLQNDPNKRPSIEQVFGKRIYF ..|..|. .. . || | . ... | ...|.|. . ...| .| ..|. ||.|||..||.. . .| SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL-QHPWF |
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| Kinase | n486.AA | Ciliate-E2 | 18-274 | 25 | 2.3e-77 | 263.32 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 18-274 Range on HMM: 1-365/365 Sequence Identity: 25% (97 aa) YEKVKLLGSGNQGKAYLCKHAQTNQQF------------------VIKQIQLSCMSDQEIQKQYKEVSILK----------------SLSHPNIIKYQDS |...|..|.||.|. |.||. ....|| ||.. . .|. ..|. . .| .|.. .|.||||||. .. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FLF-KKNYLCIVMDYAEGGDLEQRIIQA-QKANTL------FDCKTILKWFTQLCS---------------AVRFIHNQK-IIHRDIKNSNIFLDSNDNI | ..|.. .||.|..||||...|.. .| | |..| |.. ..|... |....|... ||||||| .||.. | FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I LLGDFGISKKLQNP----------K---------------------DKASTIIGTPYFMAPEICN---------QQPYTNKVDIWAIGIVLFRLVYLKYP . |||.|||.... | . . ||.|||..||||| | |..|. |.|||..|..|..... |.| KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FEGFEIFHLMLAISRGQLKFP------------------QTPSSPLKNLIQK----LLQNDPNKRPS-IEQVFGKRIY | . | ....|| . | |.||.| .|| ||.||.. .||.. . F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | n486.AA | CAMK | 23-268 | 22 | 2e-76 | 245.58 | In-house | 1-419 (425) | Show / Hide |
Range on Protein: 23-268
Range on HMM: 1-419/425
Sequence Identity: 22% (93 aa)
LLGSGNQGKAYLCKHAQTN------------QQFVIKQIQLSCMS--------------------------DQEIQKQYKEVSILKSLS-------HPNI
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TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IKYQDSFL------------FKKN-------YLCIVM---DYAEGGDL--E-QRIIQAQKAN------------TLFDCKTILKWFTQLCSAVRFIHNQK
|| . . . .. ....|| .|..||.| . |.... . |. . ..| |.||||...|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
IIHRDIKNSNIFLDSND-----------------NILLGDFGISKKLQN-----------------------PKDKASTIIGTPYFMA-PEICNQ-----
|.|||.| || ||.|. || . ||| ..|.. . .| .| |||..|| ||. |.
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
---------QPYTNKVDIWAIGIVLFRLVYLKYPFEGF-------------EIFHLMLAISRGQLKFPQTPSSP------------------------LK
..|. |.|.|..|..|. .. ..||.| .. |. | .|. || . || |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
NLIQKLLQNDPNKRPSIEQV
.||.|.|| ||.||..|||.
DLIRKMLQVDPEKRMTIEQC
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| Kinase | n486.AA | CAMKL | 18-268 | 31 | 1.7e-74 | 237.11 | In-house | 1-291 (297) | Show / Hide |
Range on Protein: 18-268 Range on HMM: 1-291/297 Sequence Identity: 31% (94 aa) YEKVKLLGSGNQGKAYLCKH-AQTNQQFVIKQIQLSCMS-DQEIQKQ------------YKEVSILKSLS---HPNIIKYQDSFLFKKN-----YLCIVM |. .| || |. || |..| |... || | . .. |. ..| ..|..|.|.|. |||||| . . ... ....|| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM DYAEGGD--LEQRIIQAQKANTLFDCKTILKWFTQLCSAVRFIHNQKIIHRDIKNSNIFLDSND--NILLGDFGISKKLQN----PKDKASTIIGTPYFM |..||. | ..|.. . . .. . . |.|..||| ..|...|.||||| || ||.|. || . ||| | . .. | .| .| |.| .| EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEICNQ--QPYT-NKVDIWAIGIVLFRLVYLKYPFEGF--------EIFHLMLAISRGQLKFP--QTPSSPLKNLIQKLLQNDPNKRPSIEQV ||||.. .|| |||||..|..|. .|. ..||.. | |.. | .| ..| .| ....||.|.|| .|.|||.|.|. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI |
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| Kinase | n486.AA | Ciliate-E2-Unclassified | 18-274 | 25 | 1.8e-69 | 237.15 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 18-274 Range on HMM: 1-352/352 Sequence Identity: 25% (90 aa) YEKVKLLGSGNQGKAYLCKHAQTNQQFVIKQIQLSCMSDQEIQKQY--------KEVSILK--------------SLSHPNIIKYQDSFLF-KKNYLCIV |...| .|.|..|| |.|.| ... |. .... . ... |... ||. ..| |.||..... . . | .|....|| YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV MDYAEGGDLEQRII-------------QAQKANTLFDCKTIL-----KWFTQLCSAVRFIHNQK-IIHRDIKNSNIFLDSND---NILLGDFGISKKLQN |.|.|||||.| | . .| . |... .. ..| |.... ..| .. ||||||| .||..|.| .| . |||||||.|. MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ P---------------KDKASTIIGTPYFM----APEICNQQPYTNK----VDIWAIGIVLFRLVYLKYPFEGFEIFH----------------LMLAIS . .....|..|||..| |||. .| | .. .|||. |..|. ... .|||.. | | NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK RGQLKFPQTP-------SSPLK-----NLIQKLLQNDPNKRPSIEQVFGKRIY ....|| | .|| .|.||.|...||||...||.. . QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | n486.AA | NEK4 | 18-275 | 36 | 3.2e-68 | 232.96 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 18-275 Range on HMM: 1-257/257 Sequence Identity: 36% (96 aa) YEKVKLLGSGNQGKAYLCKHAQTNQQFVIKQIQLSCMSDQEIQKQYKEVSILKSLSHPNIIKYQDSFLFKKN-YLCIVMDYAEGGDLEQRIIQAQKANTL |. .| | | | .| .| . |.|.| ..| | .| . .|. .| | ||||..| .|. . .|.||| . ||||| .. . || | . YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRK-LKQQK-NQF FDCKTILKWFTQLCSAVRFIHNQKIIHRDIKNSNIFLDSNDNILLGDFGISKKLQNPKDKASTIIGTPYFMAPEICNQQPYTNKVDIWAIGIVLFRLVYL . . .. || | | ..| ..|.||| | |||| | .||||||. |.| | |.|.|||||.| ||. .|| | |||..| .. .. | LEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITL KYPFEGFEIFHLMLAISRGQLK-FPQTPSSPLKNLIQKLLQNDPNKRPSIEQVFGKRIYF | |. .. |. | ||. |. | |.||. ..|. |.||||| ..| . | KHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIF-QMPYI |
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| Kinase | n486.AA | ULK | 18-274 | 26 | 1.5e-62 | 214.09 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 18-274 Range on HMM: 1-329/329 Sequence Identity: 26% (88 aa) YEKVKLLGSGNQGKAYLCKHAQT----NQQFVIKQIQLSCMSDQE--------IQKQYKEVSILKSLS--------HPNIIKYQDSFLFKK-NYLCIVMD |.. . ||.| || | .. .| |.....|.|... |. .. .| .|. |.| | ||||.|. | | .. |.. |.|. YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME YAEGGDLEQRIIQAQK------ANTLFDCKTILKWFTQLCSAVRFIHNQKIIHRDIKNSNIFLDSNDN------------ILLGDFGISKKLQNP---KD | .|||||| | . .| . . . ... | |.... ...| ..||||||| .|| .. .. . ..||| .|...|. .. YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ KASTII------GTPYFMAPEICN----QQPYTNK-VDIWAIGIVLFRLVYLKYPFEGFEIFHLM------L---------AISRGQLKFP-----QTPS . | |||..|||.| . |.||... .||| .|.... ..| |.||.. .. . | .| .|.|| .. | MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS SPLKNLIQKLLQNDPNKRPSIEQVFGKRIY . .|.||...|| |...| |.|..| . PECKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | n486.AA | ULK | 18-274 | 27 | 6.6e-62 | 211.99 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 18-274 Range on HMM: 1-324/324 Sequence Identity: 27% (88 aa) YEKVKLLGSGNQG-KAYLCKHAQT---NQQFVIKQIQLSCMSDQEIQ--------KQYKEVSILKSLS---HPN--IIKYQDSFLFKK-NYLCIVMDYAE |.. . ||.| | | | .. .| ||.. .|.|... |.... . .. .|..|.| | ||| |.|. | | . |...|.|.| . YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN GGDLEQRIIQAQK-----ANTLFDCKTILKWFTQLCSAVRFIHNQKIIHRDIKNSNIFLDSNDN------------ILLGDFGISKKLQNP---KDKAST |||||| | . .| . . . ... | |.|.. ...|...||||||| .|| . .. . ..||| .|...|. ... | GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT II------GTPYFMAPEICN----QQPYTNK-VDIWAIGIVLFRLVYLKYPFEG--FEIFHL-----------MLAISRGQLKFP-----QTPSSPLKNL . |||..|||.| . |.||... .||| .|.... ..| ||||.. . .. .. | ...|| . |. .|.| CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL IQKLLQNDPNKRPSIEQVFGKRIY |...|| |...| |.|..| . IRRMLQYDEKDRISWEEIFNHPWF |
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| Kinase | n486.AA | TyrKc | 18-275 | 19 | 1.1e-16 | 46.92 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 18-275 Range on HMM: 1-280/280 Sequence Identity: 19% (58 aa) YEKVKLLGSGNQGKAYLCKHAQTNQQFVIKQIQLSCMSDQEIQKQYKEVSILKSL--SHPNIIKYQDSFLFKK------NYLCIVMDYAEGGDLEQRIIQ .. | ||.|. |. |... .| .| .. .. .. ..| .|...| .||||.. . .. |.||| |...||| ... ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK AQKANTLFDCKTILKWFTQLCSAVRFIHNQKIIHRDIKNSNIFLDSNDNILLGDFGISKKLQNP-------KDKAS--TIIGT---PYF-MAPEICNQQP .. . |. |.. .| .. ...| ...||||. |. ...| . .||| |... . . . . . | |. |||| | HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YTNKVDIWAIGIVLFRLVYL-KYPFEG-----FEIFHLMLAISRG-QLKFPQT--------PSSPLKNLIQKLLQNDPNKRPSIEQVFGKRIYF .| | |.|. |.... . . . | .| . .... . .| .. |. .. . ..... . ||..||. ... . .| FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF |
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| Kinase | n486.AA | Pkinase_Tyr | 18-172 | 21 | 9.5e-12 | 40.42 | Pfam | 1-163 (270) | Show / Hide |
Range on Protein: 18-172 Range on HMM: 1-163/270 Sequence Identity: 21% (36 aa) YEKVKLLGSGNQGKAYLCKHA----QTNQQFVIKQIQLSCMSDQE--IQKQYKEVSILKSL-SHPNIIKYQDSFLFKKNY--LCIVMDYAEGGDLEQRII .. | ||.|. |. |... .|... .| . .... ... .|..|.|.| .||||... . .. ..||| |...||| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR QAQKANTLFDCKTILKWFTQLCSAVRFIHNQKIIHRDIKNSNIFLDSNDNILLGDFGISKKLQN . . .. |..|.. .| ... . .....||||. |. ...| . .||| .. ..| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYN |
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