Gene CC1G_15475 (C.cinerea)

CC1G_15475

Species: C.cinerea
Alias: CC1G_15475
External Links:
Annotation:

Classification

Group: CMGC
Family: CLK

Sequence

Name Sequence Type Origin Length Description Download
CC1G_15475.AA Protein None 341 None Fasta, JSON
CC1G_15475.NA RNA None 1026 None Fasta, JSON
CC1G_15475.kin_dom Protein Kinase Domain None 293 None Fasta, JSON

Protein domain

Protein domains of CC1G_15475.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase CC1G_15475.AA Pkinase 85-338 21 2.2e-36 129.7 Pfam 64-293 (293) Show / Hide 
Range on Protein: 85-338
Range on HMM: 64-293/293
Sequence Identity: 21% (58 aa)

TLMDYEVHPSHTFLVFKAYGKTLTEVMTMQ------QLLPL--PSSQIKGIAFQILSALRFLHGEDIAHTDIKPDNIVLV-DDAVASYEDFQNGEFVTKY
.| |.   ..|  .|.   ...|. ||         .  ..  .  ..| .. |||..| ..| . | | |.||.|| .. .. ...             
RLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-------------

LLKNISVKLVDYDD---FTDLHAIPRPRHLVGTSIYRPPEVIL-NMPWSTPVDIFAFGCTIAELYLGRPLFPHS----TGPSHQLAIIEERLGRFPHSFI
     .||. |      |  .   . . ...||. |..||||. . .....||....||...|...|||.||..    .  ...  | . . .... .. 
-----CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWP

DRVNRGGFNVFRPNGEVDCAEPVAQHLAVEERKHISLCILRPNLLDLLKLCLHHDDKKRCSAKAALQHRFF
   ..  |. ||.                 .        . ....|..| ||. | |||..|. .||| .|
WWCSISYFF-FRH-W-H-------------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CC1G_15475.AA CLK 98-243 29 3.9e-33 96.16 In-house 84-248 (350) Show / Hide 
Range on Protein: 98-243
Range on HMM: 84-248/350
Sequence Identity: 29% (50 aa)

LVFKAYGKTLTEVMTMQQ------LLPLPSSQIKGIAFQILSALRFLHGEDIAHTDIKPDNIVLVDD------AVASYEDFQN------GEFVTKYLLKN
.||. ||. . ..|           .|.| ..|. .|.|...|..|||   . ||| || || .||           |.. ..        .     .||
IVFELYGLSIYDFMKSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDSRFTHFDCTFKYNHKKKINKKSNNCVCHYWHVKN

ISVKLVDYDDFT-----DLHAIPRPRHLVGTSIYRPPEVILNMPWSTPVDIFAFGCTIAELYLGRPLFP
  ....|    |     . |  .    .| |  ||.||||| ..||.| |.  .|| . |||.|  ||.
THICVIDFGSATKIRFDHEHHST----IVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQ
Kinase CC1G_15475.AA CMGC 203-338 20 2.1e-29 93.05 In-house 286-513 (513) Show / Hide 
Range on Protein: 203-338
Range on HMM: 286-513/513
Sequence Identity: 20% (47 aa)

VGTSIYRPPEVILNMP----------WSTPVDIFAFGCTIAELYLG--------RPLFP----------HSTGPSHQLAIIEERLGRFPHSFIDRVNRGG
| |  ||.||..|...          ..||.|. ..|| .||.|.|        .||||          . .   .||. | . || .. ..|.. .|  
VVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRH-

FNVFRPNGE----VDC--------------------AEPVAQHLAV-----EERKHISLCI--------------------------------------L
|| | .. |    . .                     | . ...       . ...    .                                      .
FN-FCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCC

RPNLLDLLKLCLHHDDKKRCSAKAALQHRFF
 | ..|||| .|. | .|| .|. |||| .|
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF
S_TKc CC1G_15475.AA S_TKc 15-338 18 1.1e-26 95.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-338
Range on HMM: 1-231/231
Sequence Identity: 18% (64 aa)

FEERASIESTISANFHKCLFKGFDHRFGVKIIIKAIATGTDERFERKRIRRLTNALDRAANMFPHVQSLATLMDYEVHPSHTFLVFKAYGK---TLTEVM
.|    | .   .  .||  |. .... .|||              ..|||  . | .     |..  |   ..     .| ..|.   .    .| ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK---HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYI

TMQQL----LPLPSSQIKGIAFQILSALRFLHGEDIAHTDIKPDNIVLVDDAVASYEDFQNGEFVTKYLLKNISVKLVDYDDFTDLHAIPRPRHLVGTSI
  ..      |.|  ... .. ||..|| ..|   | | |.||.|| | .                        .|. |    . |      ....||  
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----------------------HIKICDFGLARQL------TTFCGTPW

YRPPEVILNMPWST-PVDIFAFGCTIAELYLGRPLFPHSTGPSHQLAIIEERLGRFPHSFIDRVNRGGFNVFRPNGEVDCAEPVAQHLAVEERKHISLCI
|..|||.   .... ..|. ..||...|.. |.|.||       |.. . ...|                                              
YMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG----------------------------------------------

LRPNLLDLLKLCLHHDDKKRCSAKAALQ-------HRFF
  | ..|... ||. | .|| .|  |||       | .|
-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CC1G_15475.AA Ciliate-E2 123-338 16 1.5e-21 70.7 In-house 146-365 (365) Show / Hide 
Range on Protein: 123-338
Range on HMM: 146-365/365
Sequence Identity: 16% (47 aa)

QIKGIAFQILS---------------ALRFLHGED-IAHTDIKPDNIVLVDDAVASYEDFQNGEFVTKYLLKNISVKLVDYDDFTDLH------AIPRPR
.|| |  |||.               ||..|| .  | | ||||.||..                          .|..|    ....       .  ..
EIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------------------------IKIIDFGLSKKYDDDNQNRTH-KQQ

HL---------------------------VGTSIYRPPEVILNMP---------WSTPVDIFAFGCTIAELYLGRPLFPHSTGPSHQLAIIEERLGRFPH
.                            .||  | .||.. . .         ... .||...|... |.  |.| |                      
CKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----------------------

SFIDRVNRGGFNVFRPNGEVDCAEPVAQHLAVEERKHISLCILRPNLLDLLKL----CLHHDDKKRCS-AKAALQHRFF
  ..    . .. . |. . | . .. | . .   |  |   . ..  ||.|     .|  | .|| . .. .|.| .|
--QQQIKQCKIDFPCPEWQKD-TQCI-Q-CKW---K--SWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CC1G_15475.AA CMGC 85-158 20 3.5e-15 45.42 In-house 102-220 (513) Show / Hide 
Range on Protein: 85-158
Range on HMM: 102-220/513
Sequence Identity: 20% (25 aa)

TLMDYEVHPS-----------------HTFLVFKAYGKTLTEVMTMQQ-------LLPLPSSQ------------IKGIA------FQILSALR--FLHG
.| |. .|.                  | .|||   ...| ... ..|        .||.  .            || .       .||| .|   ..| 
KLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHS

ED--IAHTDIKPDNIVLVDD
 .  | |.|.|| || . ..
HWGNIIHRDLKPENILINHN
Kinase CC1G_15475.AA DYRK2 208-243 55 6.4e-15 44.64 In-house 168-203 (318) Show / Hide 
Range on Protein: 208-243
Range on HMM: 168-203/318
Sequence Identity: 55% (20 aa)

YRPPEVILNMPWSTPVDIFAFGCTIAELYLGRPLFP
|| ||||| .. ....|.  |||..|||| | ||||
YRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLFP
Kinase CC1G_15475.AA DYRK 208-268 47 2.2e-13 46.6 In-house 170-229 (320) Show / Hide 
Range on Protein: 208-268
Range on HMM: 170-229/320
Sequence Identity: 47% (29 aa)

YRPPEVILNMPWSTPVDIFAFGCTIAELYLGRPLFPHSTGPSHQLAIIEERLGRFPHSFID
|| ||||| .| ....|.  .||..|||..| |||| ..   .||| | | || .|. .||
YRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFPGENEY-DQLACIMEVLGMPPKWMID
Kinase CC1G_15475.AA RCK 208-243 51 1.5e-12 35.84 In-house 179-215 (298) Show / Hide 
Range on Protein: 208-243
Range on HMM: 179-215/298
Sequence Identity: 51% (19 aa)

YRPPEVILNM-PWSTPVDIFAFGCTIAELYLGRPLFP
|| ||..|     ..|.||.|.|| ..|||  |||||
YRAPECLLRCTYYNSPMDIWAVGCIMYELYMLRPLFP
Kinase CC1G_15475.AA HIPK 92-163 37 3.4e-12 34.22 In-house 71-142 (329) Show / Hide 
Range on Protein: 92-163
Range on HMM: 71-142/329
Sequence Identity: 37% (27 aa)

HPSHTFLVFKAYGKTLTEVMTMQQLLPLPSSQIKGIAFQILSALRFLHGEDIAHTDIKPDNIVLVDDAVASY
| .||.|||      | . .   .  |||   |. | .|.| ||  |    . | |.||.|| |||     |
HKNHTCLVFEMLEQNLYDFQKQNKFMPLPLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPY
Kinase CC1G_15475.AA CDK4 208-243 52 6e-11 33.57 In-house 175-210 (290) Show / Hide 
Range on Protein: 208-243
Range on HMM: 175-210/290
Sequence Identity: 52% (19 aa)

YRPPEVILNMPWSTPVDIFAFGCTIAELYLGRPLFP
|| ||| |  .  ||||. . || .||.|  ||||.
YRAPEVLLQSYYNTPVDMWSVGCIFAEMYCRRPLFC
Kinase CC1G_15475.AA CDKL 119-153 37 1.8e-10 31.99 In-house 95-129 (286) Show / Hide 
Range on Protein: 119-153
Range on HMM: 95-129/286
Sequence Identity: 37% (13 aa)

LPSSQIKGIAFQILSALRFLHGEDIAHTDIKPDNI
....... . .|||.|. |.|  .. | |||| ||
VDEHVVRKYMWQILKAINFCHKHNCIHRDIKPENI
Kinase CC1G_15475.AA HIPK 208-243 52 3.6e-10 27.71 In-house 169-204 (329) Show / Hide 
Range on Protein: 208-243
Range on HMM: 169-204/329
Sequence Identity: 52% (19 aa)

YRPPEVILNMPWSTPVDIFAFGCTIAELYLGRPLFP
|| ||.|| .|    .|... || ||||.||.||.|
YRAPEIILGLPFCENHDMWSLGCVIAELFLGWPLYP
Kinase CC1G_15475.AA RCK 309-338 36 1.3e-09 26.4 In-house 269-298 (298) Show / Hide 
Range on Protein: 309-338
Range on HMM: 269-298/298
Sequence Identity: 36% (11 aa)

PNLLDLLKLCLHHDDKKRCSAKAALQHRFF
.....|.. .|  | .|| .|..||||..|
QDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase CC1G_15475.AA DYRK 86-157 32 2e-09 31.66 In-house 66-139 (320) Show / Hide 
Range on Protein: 86-157
Range on HMM: 66-139/320
Sequence Identity: 32% (24 aa)

LMDYEVHPSHTFLVFKAYGKTLTEVMTMQQLLPL-PSSQIKGIAFQILSALRFLHGE-DIAHTDIKPDNIVLVD
. || .|  |...||  .   | |..      .. . . .. .|.||| .|.||| . .| | |.||.||.|..
MYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQ
Kinase CC1G_15475.AA MAK 208-243 56 3e-09 25.15 In-house 213-249 (352) Show / Hide 
Range on Protein: 208-243
Range on HMM: 213-249/352
Sequence Identity: 56% (21 aa)

YRPPEVILN-MPWSTPVDIFAFGCTIAELYLGRPLFP
|| ||| |     | |.|. |.||  ||||  |||||
YRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFP
Kinase CC1G_15475.AA CDK4 119-155 40 7e-09 26.37 In-house 107-143 (290) Show / Hide 
Range on Protein: 119-155
Range on HMM: 107-143/290
Sequence Identity: 40% (15 aa)

LPSSQIKGIAFQILSALRFLHGEDIAHTDIKPDNIVL
.|  .|| . .|.|... |||   | | | ||.|| .
MPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILV
Kinase CC1G_15475.AA CDKL 208-243 45 8.6e-09 26.19 In-house 165-201 (286) Show / Hide 
Range on Protein: 208-243
Range on HMM: 165-201/286
Sequence Identity: 45% (17 aa)

YRPPEVILN-MPWSTPVDIFAFGCTIAELYLGRPLFP
|| ||  .  .  ..|||| | || .||.  | ||.|
YRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLWP
Kinase CC1G_15475.AA DYRK2 128-155 57 1.5e-08 23.54 In-house 108-135 (318) Show / Hide 
Range on Protein: 128-155
Range on HMM: 108-135/318
Sequence Identity: 57% (16 aa)

AFQILSALRFLHGEDIAHTDIKPDNIVL
|..|| .||||| ..| | | || ||.|
AHSILQCLRFLHKNNIIHCDLKPENILL
Kinase CC1G_15475.AA MAK 119-156 39 2.8e-08 21.99 In-house 128-165 (352) Show / Hide 
Range on Protein: 119-156
Range on HMM: 128-165/352
Sequence Identity: 39% (15 aa)

LPSSQIKGIAFQILSALRFLHGEDIAHTDIKPDNIVLV
.| . |. | .||| .| |.|     | |.|| || ..
FPEPVIRNIMYQILQGLAFMHKHGFFHRDMKPENIMCM
Kinase CC1G_15475.AA CLK 311-338 50 1.3e-07 18.13 In-house 323-350 (350) Show / Hide 
Range on Protein: 311-338
Range on HMM: 323-350/350
Sequence Identity: 50% (14 aa)

LLDLLKLCLHHDDKKRCSAKAALQHRFF
| ||.. .|  |  || ..| ||||.||
LFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase CC1G_15475.AA CDK4 312-338 44 2e-07 21.33 In-house 264-290 (290) Show / Hide 
Range on Protein: 312-338
Range on HMM: 264-290/290
Sequence Identity: 44% (12 aa)

LDLLKLCLHHDDKKRCSAKAALQHRFF
.|||. .|  . .|| || ..||| .|
DDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase CC1G_15475.AA DYRK 308-338 38 4.7e-07 22.71 In-house 290-320 (320) Show / Hide 
Range on Protein: 308-338
Range on HMM: 290-320/320
Sequence Identity: 38% (12 aa)

RPNLLDLLKLCLHHDDKKRCSAKAALQHRFF
. ...|..| ||  | .|| ... |||| .|
DHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase CC1G_15475.AA RCK 118-153 44 6.8e-07 17.59 In-house 99-136 (298) Show / Hide 
Range on Protein: 118-153
Range on HMM: 99-136/298
Sequence Identity: 44% (17 aa)

PLPSSQ--IKGIAFQILSALRFLHGEDIAHTDIKPDNI
.||..|  || | .||| .| ..|   . | |.|| ||
YLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENI
Kinase CC1G_15475.AA MAK 310-338 27 7.4e-07 17.39 In-house 324-352 (352) Show / Hide 
Range on Protein: 310-338
Range on HMM: 324-352/352
Sequence Identity: 27% (8 aa)

NLLDLLKLCLHHDDKKRCSAKAALQHRFF
....|.| .|  | .||  |. ......|
DAIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase CC1G_15475.AA CDKL 306-338 30 7.6e-07 19.44 In-house 254-286 (286) Show / Hide 
Range on Protein: 306-338
Range on HMM: 254-286/286
Sequence Identity: 30% (10 aa)

ILRPNLLDLLKLCLHHDDKKRCSAKAALQHRFF
.. . .||..| ||| |  .| ... ...| .|
KSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase CC1G_15475.AA DYRK2 309-338 30 9.7e-05 10.98 In-house 289-318 (318) Show / Hide 
Range on Protein: 309-338
Range on HMM: 289-318/318
Sequence Identity: 30% (9 aa)

PNLLDLLKLCLHHDDKKRCSAKAALQHRFF
.|..| .| |.. | ..| ... ||.| ..
ENFIDFIKRCFEWDPSERMTPSQALKHPWI
TyrKc CC1G_15475.AA TyrKc 19-338 12 0.000552 -158.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-338
Range on HMM: 1-280/280
Sequence Identity: 12% (46 aa)

ASIESTISANFHKCLFKGFDHRFGVKIIIKAIATGTDERFERKRIRRLTNALDRAANMFPHV------------------------QSLATLMDYEVHPS
 . . ..   .    .||      ..  .| .  ..              .. | |..  ..                        . |  .| |  | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

-HTFLVFKAYGKTLTEVMTMQQLLPLPSSQIKGIAFQILSALRFLHGEDIAHTDIKPDNIVLVDDAVASYEDFQNGEFVTKYLLKNISVKLVDY---DDF
 . .|  .                 |. ..   ...|| .  ..||   . | |.   |. . ..                       ||  |     | 
LKDYLRKHRPK--------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---------------------TVKISDFGLSRDI

TDL------HAIPRPR-HLVGT--SIYR--PPEVILNMPWSTPVDIFAFGCTIAELY-LGRPLFPHS----TGPSHQLAIIEER--LGRFPH----SFID
.|       .   |.. |  |     .|  .||.|     .|  |...|| .. |.. .| .  |        ... .. ....  . . |.    |   
YDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---

RVNRGGFNVFRPNGEVDCAEPVAQHLAVEERKHISLCILRPNLLDLLKLCLHHDDKKRCSAKAALQHRFF
                                  .  .  . . .. | | |.| ..|.. ..   |..|
----------------------------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CC1G_15475.AA HIPK 308-338 32 0.003328 5.39 In-house 299-329 (329) Show / Hide 
Range on Protein: 308-338
Range on HMM: 299-329/329
Sequence Identity: 32% (10 aa)

RPNLLDLLKLCLHHDDKKRCSAKAALQHRFF
| .  ..||  .  | .|| .  .||.|.| 
RREFVHVLKKMCTWDAHKRITPCEALNHPFV