Gene CC1G_13958 (C.cinerea)

CC1G_13958

Species: C.cinerea
Alias: CC1G_13958
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-ccin

Sequence

Name Sequence Type Origin Length Description Download
CC1G_13958.AA Protein None 521 None Fasta, JSON
CC1G_13958.NA RNA None 1566 None Fasta, JSON
CC1G_13958.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of CC1G_13958.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CC1G_13958.AA TKL 261-517 21 8.5e-53 181.72 In-house 1-364 (364) Show / Hide 
Range on Protein: 261-517
Range on HMM: 1-364/364
Sequence Identity: 21% (78 aa)

VAGGTHSDIWEGLWLG---------RKKVALKGLRNIKAD---------------------DPRAK---LRIEREIKTWSSLQNEHILPFYGIVTDIGT-
.  |. . .. | | |          | || | ..    |                     || |.    ..|.||.  |.|. ..|..|.|......  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------HIHMVSPWQENGNVLDYLKKQPNVNRLRIIKGAARGLAYLHSMK--------IVHGNVKCTNILVMDNGE--------------ACICD
           ....|  . ..|. |.||       |.|.....|||..|||||.        |.| . |  |||| .|..              ..|||
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICD

FGMSKLIEEVTEKAASA---------------TLTAAGSARWLAPELIDGTI--------------SSPTFATDTYSFAMAVLELLTGKYPFAERKRD--
|| |. ... ... ...               | |  |. ||.|||...|..              .. . ..| |||..   |.||.. |... . .  
FGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPM

------ASVIHDVVVMKQTPARP------QDPRVCVWLTDE---LWNLLGGCWHNSAESRPTMAEVTGEL
         .  |.. .. | .|        . . .. .|    . .|.  ||.  .|.||.. |.. .|
IFQDPFEEMFMMVCDKGLRPPIPPIWQNHH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase CC1G_13958.AA TK 267-517 15 1.4e-34 112.83 In-house 14-486 (486) Show / Hide 
Range on Protein: 267-517
Range on HMM: 14-486/486
Sequence Identity: 15% (72 aa)

S--DIWEGLWLGRK--------------------------KVALKGLRNIKADDPRAKLR--------------IEREIKTWSS--LQNEHILPFYGIVT
|  ....|.| ||.                          .|| | |.   |.......                 .|.|  ..  .. ..|. .||..|
SFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCT

DIGT-----------HIHMVSPWQENGN----VLDYLKKQP-----------------------------------------------------------
. ..           .. .|  . ..|.     .|||.| .                                                           
QGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLT

--------------------NVNRLRIIKGAARGLAYLHSM------KIVHGNVKCTNILVMDNGE-----------ACICDFGMS--------KLIE--
                       .| .   .|.|..||||.      ..||... . |.|| .|.            . |.|||.|        . |.  
TKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSD

EVTEKAASATL--------------------TAAGSARWLAPELIDGTI-------SSPTFATDTYSFAMAVLELLT-GKYPFAERKRDASVIH---DVV
.   .. | .                      .    ||.||| ... .          | ..| .||   . |..| |. |...   .  |..   .  
DDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQE

VMKQTPAR-----------------PQDPRVCVWLT----------DELWNLLGGCWHNSAESRPTMAEVTGEL
||..  .                  || |  . |            .|.  |.  |||  .| |||....  .|
VMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
S_TKc CC1G_13958.AA S_TKc 255-520 19 3.8e-29 104.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 255-520
Range on HMM: 1-231/231
Sequence Identity: 19% (56 aa)

RRSDHAVAGGTHSDIWEGLWLG-RKKVALKGLRNIKADDPRAKLRIEREIKTWSSLQNEHILPFYGIVTDIGTHIHMVSPWQEN--GNVLDYLKK-----
 .    .  |. .  . . . .  ..||.| ..           .|.|||.  .. . ..|  .|..  |  .|..||    ..  |...||.||     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----QPNVNRLRIIKGAARGLAYLHSMKIVHGNVKCTNILVMDNGEACICDFGMSKLIEEVTEKAASATLTAAGSARWLAPELIDGTISSPTF-ATDTYS
     |     ....  ...|.|.||..|.|  .|  |||. .  .  |||||.....            |  |.  ..|||..     . .. . | .|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL-----GYGKCKCDWWS

FAMAVLELLTGKYPFAERKRDASVIHDVVVMKQTPARPQDPRVCVWLTDELWNLLGGCWHNSAESRPTMAEVTG-E-----LDLF
.   . |.|.|. ||     .  .. ....                 ..|..... .|..   | |||  |.   |        |
CGCILYEMLCGYPPFP----QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CC1G_13958.AA Pkinase 277-513 21 9.4e-25 88.6 Pfam 24-287 (293) Show / Hide 
Range on Protein: 277-513
Range on HMM: 24-287/293
Sequence Identity: 21% (60 aa)

RKKVALKGLRNIKADD--PRAKLRIEREIKTWSSLQNEHILPFYGIVTDIGTHIHMVSPWQENG----NVLDYLK--KQPNV-----NRLRIIKGAARGL
.|.||.| ..  ....  .....|. .||.   .|. ..|. .|....| ..||.|| .. |.|       ||..  .. ..        ....  .|||
GKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGL

AYLHSMKIVHGNVKCTNILVMDNGEA----CICDFGMSKLIEEVTEKAASATLTAAGSARWLAPELIDGTISSPTFATDTYSFAMAVLELLTGKYPFAER
.|.|||.|.|  .|  |||. .||.     .||||| .|...   .   | . | .|. ...|||.|  . .  . . | .|.   . |.|.|. || ..
EYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMWSCGCILYEMLCGRPPFPGH

----KRDASVIHDVVVMKQTPARPQDP---------------RVCVWLTDELWNLLGGCWHNSAESRPTMAEV
    ..|  .... . .....   . .               .. . ...|.  .. .|..   ..||| ...
CWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQI
Kinase CC1G_13958.AA STE 291-458 20 2.8e-23 79.12 In-house 67-270 (359) Show / Hide 
Range on Protein: 291-458
Range on HMM: 67-270/359
Sequence Identity: 20% (44 aa)

DDPRAKLRIEREIKTWSSLQ--NEHILPFYGIVTDIG------THIHMVSPWQENGNVLDYLK-----------------KQPNVNRLRIIKGAARG-LA
...  . .|..|||. . ..   ..|  .||   . |      ......  . ..| . | .|                 . |     .|..   .| |.
KNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLY

YLHSMKIVHGNVKCTNILVMDNGEACICDFGMSK-LIEEVTEK-----------AASATLTAAGSARWLAPELIDGTISSPT-----FATDTYSFAMAVL
||||..|.|  .|. |||.     . .|||| .. |.......            .. . | .|.  | ||| |..  .. .     .  | .|.   ..
YLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTII

ELLTGKYPFAE
|..|||.|...
EMATGKPPWHD
Kinase CC1G_13958.AA MLK 360-517 25 8.3e-23 76.04 In-house 134-291 (291) Show / Hide 
Range on Protein: 360-517
Range on HMM: 134-291/291
Sequence Identity: 25% (43 aa)

ARGLAYLHSMK---IVHGNVKCTNILVMD------NGEACICDFGMSKLIEEVTEKAASATLTA-AGSARWLAPELIDG-TISSPTFATDTYSFAMAVLE
|||..|||||.   |.|   |  |||...      .| . ||||| |.   .....   .. .  ||...| ||| |     .  . . | .|...   |
ARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR---DWHQMC--TNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWE

LLTGKYPFAERKRDASVIHDVVVMKQTPARPQDPRVCVWLTDELWNLLGGCWHNSAESRPTMAEVTGEL
.||.. |...    . ..  |.. ...|. |..        . . .|.  ||.  ...||.....  .|
MLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST------CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase CC1G_13958.AA Pkinase_Tyr 268-442 25 9.4e-23 77.69 Pfam 14-200 (270) Show / Hide 
Range on Protein: 268-442
Range on HMM: 14-200/270
Sequence Identity: 25% (50 aa)

DIWEGLWL-----GRKKVALKGLRNIKADDPRA--KLRIEREIKTWSSL-QNEHILPFYGIVTDIGTH--IHMVSPWQENGNVLDYLKKQ-------PNV
....| |      .. .|| | |..    ....  .    ||.|. ..| ....|. .||..|| | .  | .| .  ..|. ||||.|.       .  
EVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMK

NRLRIIKGAARGLAYLHSMKIVHGNVKCTNILVMDNGEACICDFGMSKLIEEVTEKA-ASATLTAAGSARWLAPELIDGTISSPTFATDTYSF
  | .    |.|..||.|....|  . . |.|| .|. . |||||....| . ..    ... .     .|.||| |   .   | ..| .||
DLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGK-LPIKWMAPECINYGK--FTTKSDVWSF
Kinase CC1G_13958.AA RIPK 299-517 23 1.6e-20 66.63 In-house 43-290 (290) Show / Hide 
Range on Protein: 299-517
Range on HMM: 43-290/290
Sequence Identity: 23% (60 aa)

IEREIKTWSSLQNEHILPFYGIVTDI-----GTHIHMVSPWQENGNVLDYLKKQPN-----VN---RLRIIKGAARGLAYLHSMK--IVHGNVKCTNILV
. .| |   .|..|||.| ||.. .      .  .  |    |||.  . |. ..      .    | |.|.  ..|  |||||.  | |   |  ||||
QKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQHHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILV

MDNGEACICDFGMSKLIEEVTEKA-------ASATLTAA--GSARWLAPELIDGTISSP----TFATDTYSFAMAVLELLTGKYPFAERKRDASVIHDVV
  |  . | ||| ..  .  . .         . .  .   |    ..||..    ..|    | . | ||||. . |.||.| |...|| .   .  ..
DNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCK

------VMKQTPARPQDPRVCVWLTDELWNLLGGCWHNSAESRPTMAEVTGEL
      .   ....|..| .      .. .|.  ||.  ...||.  |.. . 
QGHRPCLQPVPEYWPEPPHC-----EQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase CC1G_13958.AA UTK 279-442 22 4.1e-19 62.02 In-house 31-226 (296) Show / Hide 
Range on Protein: 279-442
Range on HMM: 31-226/296
Sequence Identity: 22% (46 aa)

KVALKGLRNIKADDPRAKL---RIEREIK---TWSSLQ-NEHILPFYGIVTDIGTHIHMVSPWQENGNVLDYLKKQPN--------VN---RLRIIKGAA
.||.| ..  .||.....    .. .| .     . ..  ...| ..|..|. .  . .|.  .|||. ..|| ...         ..   ||      |
DVAVKVCQ-HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIA

RGLAYLHSMKIVHGNVKCTNILVMDNG-------EACICDFG---MSKLIE---------EVTEKAASATLTAAGSARWLAPELIDGTISSPTFATDTYS
||..||||...||... . |.|| ...        . |.|||   ||...          |  .  |.    ..   || ||| ..     .|...| .|
RGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWP--IRWMAPEALTHHT-RFTTKSDVWS

F
|
F
Kinase CC1G_13958.AA Jak 300-451 23 5.7e-18 59.87 In-house 57-223 (299) Show / Hide 
Range on Protein: 300-451
Range on HMM: 57-223/299
Sequence Identity: 23% (40 aa)

EREIKTWSSLQNEHILPFYGIVTDIGT-HIHMVSPWQENGNVLDYLK-----KQPNVNR-----LRIIKGAARGLAYLHSMKIVHGNVKCTNILVMDNGE
.||| ..|.....||. ..|......   . ||    . |  .|||.     . ..||.     .   |. ..|. ||......||.|.. ||||  .| 
HREISIMSQWSHKHIVKYHGVCCHWCQDEYCMVMEYWCYGPLDDYLHKVKERHKWCVNHTEDWKMQFAKQICWGMHYLEDKRYIHGDVCARNILVDREGH

---ACICDFGMSKLIEEVTEKAASATLTAAGSA-----RWLAPELIDGTISSPTFATDTYSFA-MAVLELL-T
    .| .|. .. . ...|      .  . .      .| |||..    ...| |.|  ||.     |.. .
WCCVKIPFFKLMDPWCSDKE------YYREMMDRDERIPWYAPECLTNCKFYLTLAMDKWSFGRVTLWEICNC
Kinase CC1G_13958.AA TK-Unique 312-517 21 5.7e-18 58.65 In-house 64-294 (294) Show / Hide 
Range on Protein: 312-517
Range on HMM: 64-294/294
Sequence Identity: 21% (51 aa)

EHILPFYGIVTDIGTHIHMVSPWQENGNVLDYLK-KQPN-------------------VNR---LR------IIKGAARGLAYLHS--MKIVHGNVKCTN
..|. ..|. |. .   ... .....|| ..||. ..|.                    .|   .       .... |.|..||.|  .||||...   |
PNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARN

ILVMDNGEACICDFGMSKLIEEVTEKAASATLTAAGSARWLAPELIDGTISSP-TFATDTYSFAMAVLELLT-GKYPFAERKRDASVIHDVVVMKQTPAR
.|. ..... ||||||.. ..  ... .. .     . ||.||| .  .     |  .| .||.    |..| |..|. . . .  .. ..  ..    |
VLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKD-IMECIRDGY----R

PQDPRVCVWLTDELWNLLGGCWHNSAESRPTMAEVTGEL
...|  |   ..|. ||.  ||. ..|.||. .... .|
MPQPEHCC--SHEMYNLMKSCWQWEPEERPSFRQIKHRL
TyrKc CC1G_13958.AA TyrKc 255-517 22 9.7e-18 64.14 SMART 1-280 (280) Show / Hide 
Range on Protein: 255-517
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

RRSDHAVAGGTHSDIWEGLWLGRKKVALKGLRNIKADDPRAKLRIEREIKTWSSL--QNEHILPFYGIVTDIG------THIHMVSPWQENGNVLDYLKK
 . ..    |    ...| |    .|| | |.. .      .  . ||..  ..|  ....|. .||..|. |        . .|    ..|. .|||.|
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

QPN----VNRLRIIKGAARGLAYLHSMKIVHGNVKCTNILVMDNGEACICDFGMSKLIEEV-------TEKAASA--TLTAAGSARWLAPELIDGTISSP
  .       | .   .|.| .||||....|    . |.|| .|. . |.|||.|. |..          . ..      .    ||.||| |    .  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKF

TFATDTYSFAMAVLELLTGKYPFAER-----KRDASVIHDVVVMKQTPARPQ-----DPRVCVWLTDELWNLLGGCWHNSAESRPTMAEVTGEL
|...| .||     |..|   .  .      . .. ||..|   .  |  |           |  .||. ..   |||  .|.|||..|.  ..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF----VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CC1G_13958.AA TKL-Unique 348-517 25 1.9e-17 58.27 In-house 108-290 (290) Show / Hide 
Range on Protein: 348-517
Range on HMM: 108-290/290
Sequence Identity: 25% (49 aa)

PNVNRLRIIKGAARGLAYLHSMK--IVHGNVKCTNILVMDN-----GEACICDFGMSKLIEEVTEKAASAT-----LTAAGSARWLAPELIDG---TISS
.. .|..... .|.|. |||. .  | |.. | .|.||  |       . ||||| ||.    ... ..        |  ||.||.|||.. .   ..| 
NMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSE

PTFATDTYSFAMAVLELLTGKY------PFAERKRD--ASVIHDVVVMKQTPARPQDPRVCVWLTDELWNLLGGCWHNSAESRPTMAEVTGEL
     | |||.. . |..|.|       |. .  ..  ....|..   .. |  |..      .  |. .|.  |||   . ||.  |.  .|
---KSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYM-EENYRPPIPNH------CPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase CC1G_13958.AA Dicty4-Unclassified 360-458 31 2.2e-17 56.09 In-house 119-210 (263) Show / Hide 
Range on Protein: 360-458
Range on HMM: 119-210/263
Sequence Identity: 31% (31 aa)

ARGLAYLHSMKIVHGNVKCTNILVMDNGEACICDFGMSKLIEEVTEKAASATLTAAG-SARWLAPELIDGTISSPTFATDTYSFAMAVLELLTGKYPFAE
|.|...||.  ..|  .|  |||.  .  . | |||.|  |.         ..|. .   .| .||   .   | . . | ||.||   ||.||  |. |
AQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVID------FNFNMTTIAGTPKWESPECLMHE--SYNQKSDVYSYAMMLYELATGDEPYQE
Kinase CC1G_13958.AA UTK 490-517 21 2.6e-05 14.12 In-house 269-296 (296) Show / Hide 
Range on Protein: 490-517
Range on HMM: 269-296/296
Sequence Identity: 21% (6 aa)

DELWNLLGGCWHNSAESRPTMAEVTGEL
.....|.  ||| . . ||.. ... ..
HPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase CC1G_13958.AA Pkinase_Tyr 489-517 41 2.8e-05 18.5 Pfam 242-270 (270) Show / Hide 
Range on Protein: 489-517
Range on HMM: 242-270/270
Sequence Identity: 41% (12 aa)

TDELWNLLGGCWHNSAESRPTMAEVTGEL
.||. .|.  |||  .| |||..|.  .|
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase CC1G_13958.AA Dicty4-Unclassified 499-517 47 3.6e-05 13.63 In-house 245-263 (263) Show / Hide 
Range on Protein: 499-517
Range on HMM: 245-263/263
Sequence Identity: 47% (9 aa)

CWHNSAESRPTMAEVTGEL
||||.   |||| ...  |
CWHNDPNKRPTMNQIIQYL