Gene AqueK005 (A.queenslandica)

AqueK005

Species: A.queenslandica
Alias: AqueK005
External Links:
Annotation:

Classification

Group: AGC
Family: DMPK
Subfamily: GEK

Sequence

Name Sequence Type Origin Length Description Download
AqueK005.AA Protein None 1850 None Fasta, JSON
AqueK005.kin_dom Protein Kinase Domain None 269 None Fasta, JSON

Protein domain

Protein domains of AqueK005.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK005.AA DMPK 80-348 66 2.3e-272 683.62 In-house 1-270 (270) Show / Hide 
Range on Protein: 80-348
Range on HMM: 1-270/270
Sequence Identity: 66% (180 aa)

FEVLEVIGRGAFGEVKVVRLKSTNKVYALKVLNKAEMLQRQTTACFKEERDVLVFGNRDWITKLHYAFQDKNNLYFVMDYYLGGDVLTLLSKFEDRLTED
||.| |||||.||||.||| |.||.||| |..||.||| | .||||.||||..|.||. |||.|||||||.|.||.||.|. ||| |||.|..|||. ||
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

MVKFYASEMILAIHSIHDLGYVHRDIKPDNVLIGKDGHIRLADFGSCLKMDSNRKVNSTTAVGTPDYISPEILQAMEDG-RGVYGPECDWWSLGICIYEM
| .||  ||.||||||| .|||||||||||.|. . |||.|||||||.||...  |.| .|||||||||||.||||||. .| |||||||||.|.|.|||
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSCMKMNRDGMVRSKVAVGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEM

LFGETPFYAESLLQTYSKIMQH-KTLFSFPSDEDSIVVSKDAKNLIKNLICDAEERLGQSGIDDFKKHPFF
|.|||||||.|| .||.||| | |. .|||.|.  ..||..||.||. |.||.|||||. |..|||.||||
LYGETPFYADSLVETYGKIMNHCKNHLSFPDDPK-WDVSEEAKDLICQLLCDREERLGRNGYEDFKCHPFF
Kinase AqueK005.AA GEK 80-348 71 1.3e-178 599.63 In-house 1-269 (269) Show / Hide 
Range on Protein: 80-348
Range on HMM: 1-269/269
Sequence Identity: 71% (193 aa)

FEVLEVIGRGAFGEVKVVRLKSTNKVYALKVLNKAEMLQRQTTACFKEERDVLVFGNRDWITKLHYAFQDKNNLYFVMDYYLGGDVLTLLSKFEDRLTED
||.| |||||||||| ||..|.|..|||.|.||| |||.|  ||||.|||||||.| | |||.||||||| |.||.|||||.|||.||||||||||| ||
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

MVKFYASEMILAIHSIHDLGYVHRDIKPDNVLIGKDGHIRLADFGSCLKMDSNRKVNSTTAVGTPDYISPEILQAMEDGRGVYGPECDWWSLGICIYEML
| .|| .||..||.|.| |.||||||||||||. . ||||||||||||.|. .  |.|  |||||||||||||||||||.| |||||||||||.|.||||
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGSCLRMNKDGMVQSNVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEML

FGETPFYAESLLQTYSKIMQHKTLFSFPSDEDSIVVSKDAKNLIKNLICDAEERLGQSGIDDFKKHPFF
.|||||||||| .||.|||.||  |.|||.|  ..||..|| ||..||| .|.|||. ||.||||||||
YGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQDFKKHPFF
Kinase AqueK005.AA AGC 80-348 30 1.1e-169 442.98 In-house 1-395 (395) Show / Hide 
Range on Protein: 80-348
Range on HMM: 1-395/395
Sequence Identity: 30% (125 aa)

FEVLEVIGRGAFGEVKVVRLK------STNKVYALKVLNKAE--------MLQRQTTAC-------FKEERDVLVFGN----------RDWITK-LHYAF
||.| |||.|.||.|  || |      .|.|.||.|||.|..        |...  |..       ..|||..|.  |           ..|.| |||.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDKNN--LYFVMDYYL---------GG-DVLTLLSK--FEDRLTEDMVKFYASE-------MILAIHSIHD-LGYVHRD-IKPDNVLIGKDGHIRLADFG
|||..  |||||.|.          || . .. | .   | |..|....|||.|       ..||....|. .|..||| .||.|.|. .||||.|.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

SCLK--------------------------------------MDSNR-----------KVNSTTAVG--TPDYISPEILQAMEDGRGVYGPECDWWS--L
.| .                                      ...|.           ..  .| .|  ||.|..||||         ||..|||||  |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---------YGKACDWWSFGL

GICIYEMLFGETPFYAESLL----------QTYSKIM------QHKTLFSFP---SDEDSIVVSKDAKNLIKNLIC-DAEERLG--QS-----GIDDFKK
|...||||.| .|||...            ... |||      ..|  | ||     ..   .|..||.||| |.| | |.|||  ..     |... |.
GCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKN

HPFF
||.|
HPWF
Kinase AqueK005.AA CRIK 80-348 47 1.2e-136 438.33 In-house 1-272 (272) Show / Hide 
Range on Protein: 80-348
Range on HMM: 1-272/272
Sequence Identity: 47% (131 aa)

FEVLEVIGRGAFGEVKVVRLKSTNKVYALKVLNKAEMLQRQTTACFKEERDVLVFGNRDWITKLHYAFQDKNNLYFVMDYYLGGDVLTLLSKFEDRLTED
|||  .||.| ||.|.||| | || .|| ||. |...| ..  . |.||||..   |  |...| |||||..||| .| |  ||| | |.. ..| . |.
FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN

MVKFYASEMILAIHSIHDLGYVHRDIKPDNVLIGKDGHIRLADFGSCLKMDSNRKVNSTTAVGTPDYISPEILQAMED---GRGVYGPECDWWSLGICIY
|..||  | |.|.||.|  |||||||||.|.||   ||| ||||||  ||..|  |||   ||||||. ||.|| |     ..| || .|||||.||  |
MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFGSAAKMNRNNHVNSKMPVGTPDYMAPEVLQTMNGYKLSKGMYGVDCDWWSMGIIAY

EMLFGETPFYAESLLQTYSKIMQ------HKTLFSFPSDEDSIVVSKDAKNLIKNLICDAEERLGQSGIDDFKKHPFF
||  | |||   .  .|||.||        . . |||   |.  || .. .||. |.|.  .||.  ..   . ||||
EMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFP---DDPKVSPNYRDLIQSLLCNQSKRLKYEQL---CCHPFF
Kinase AqueK005.AA ROCK 80-348 54 4.7e-133 448.33 In-house 1-263 (263) Show / Hide 
Range on Protein: 80-348
Range on HMM: 1-263/263
Sequence Identity: 54% (147 aa)

FEVLEVIGRGAFGEVKVVRLKSTNKVYALKVLNKAEMLQRQTTACFKEERDVLVFGNRDWITKLHYAFQDKNNLYFVMDYYLGGDVLTLLSKFEDRLTED
|... ||||||||||..|| ||..||||.|.|.| ||..|   | | ||||.. . | .|| .|||||||.  || ||||  |||.  |.|...  . | 
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVNLMSNYD--VPEK

MVKFYASEMILAIHSIHDLGYVHRDIKPDNVLIGKDGHIRLADFGSCLKMDSNRKVNSTTAVGTPDYISPEILQAMEDGRGVYGPECDWWSLGICIYEML
  .||  |..||. .|| .|..|||.||||.|. | ||..||||| |.||. |  | . ||||||||||||.|..   . | || |||||| |. |||||
WARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTCMKMNKNGMVRCDTAVGTPDYISPEVLKSQG-QDGEYGRECDWWSVGVFIYEML

FGETPFYAESLLQTYSKIMQHKTLFSFPSDEDSIVVSKDAKNLIKNLICDAEERLGQSGIDDFKKHPFF
.|.|||||.||  ||||||.||.  .|| |   . .||.||.||.  . |.|.|||. |.|| |.|.||
VGDTPFYADSLVGTYSKIMDHKNSLKFPDD---VEISKQAKDLICKFLTDREQRLGRNGVDDIKQHKFF
Kinase AqueK005.AA S_TKc 80-348 30 2e-90 307.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 80-348
Range on HMM: 1-231/231
Sequence Identity: 30% (86 aa)

FEVLEVIGRGAFGEVKVVRLKSTNKVYALKVLNKAEMLQRQTTACFKEERDVLVFGNRDWITKLHYAFQDKNNLYFVMDYYLG--GDVLTLLSKFEDR--
.|.|..||.||||.|. .| |.|....|.|...            .. |...|   . ..| ||...||| ..||.||.|  |  ||..... |   .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEDMVKFYASEMILAIHSIHDLGYVHRDIKPDNVLIGKDGHIRLADFGSCLKMDSNRKVNSTTAVGTPDYISPEILQAMEDGRGVYGP-ECDWWSL
   ..| ...||. ....|.  .|..| .|||.||.|.|. .  || ..|||.. ..        || .|||.|..||.|         ||. .|||||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--------GYGKCKCDWWSC

GICIYEMLFGETPFYAESLLQTYSKIMQHKTLFSFPSDEDSIVVSKDAKNLIKNLIC-DAEERLGQSGIDD----FKKHPFF
|...|||| |..||.   . ... ||.                 |..||..|... . | |.|..   .       |.||.|
GCILYEMLCGYPPFP--QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK005.AA NDR 80-224 51 2.2e-84 260.09 In-house 1-149 (350) Show / Hide 
Range on Protein: 80-224
Range on HMM: 1-149/350
Sequence Identity: 51% (77 aa)

FEVLEVIGRGAFGEVKVVRLKSTNKVYALKVLNKAEMLQRQTTACFKEERDVLVFGN--RDWITKLHYAFQDKNNLYFVMDYYLGGDVLT---LLSKFED
||....||.|||||| .|| |.|...||.|...|.||.... .|  . |||...  .   .|..|| |.||||..||.||.|  |||  |   ||.|. |
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKM-D

RLTEDMVKFYASEMILAIHSIHDLGYVHRDIKPDNVLIGKDGHIRLADFG
 .|||. .|| .||..||.|.| .||.|||||||| || ||||| | |||
IFTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFG
Kinase AqueK005.AA RSK 83-348 35 5.6e-82 278.66 In-house 1-278 (278) Show / Hide 
Range on Protein: 83-348
Range on HMM: 1-278/278
Sequence Identity: 35% (100 aa)

LEVIGRGAFGEVKVVRLK---STNKVYALKVLNKAEMLQRQT-TACFKEERDVLVFGN-RDWITKLHYAFQDKNNLYFVMDYYLGGDVLTLLSKFEDR--
|.| |.|..|.| ..| .    |...|| |||.||.. |||. |.  ..||..|   .    | .||||||..  || .|.|  ||. .| |.| .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LTEDMVKFYASEMILAIHSIHDLGYVHRDIKPDNVLIGK---DGHIRLADFGSCLKMDSNRKVNSTTAVGTPDYISPEILQAMEDGRGVYGPECDWWSLG
..|| ..||..| .||.  .|..| .|||.||.|.|      .|||.| ||| | ... . .    | ..| .|. ||.|   . ..| ..  |||||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWWSLG

ICIYEMLFGETPFYA---ESLLQTYSKIMQHKTLFSFPSDEDSIVVSKDAKNLIKNLIC-DAEERLG--QSGIDDFKKHPFF
. .||||.| .||..   ..  ..  .|.. |  ||.......  .|..||.||. . . | . |||   ..... |.||.|
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGK--FSLTMPNWQ-YLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase AqueK005.AA AktR 80-348 32 2.1e-73 250.15 In-house 1-268 (268) Show / Hide 
Range on Protein: 80-348
Range on HMM: 1-268/268
Sequence Identity: 32% (91 aa)

FEVLEVIGRGAFGEVKVVRLK-STNKVYALKVLNKAEMLQRQTTACFKEERDVLVFGNRD-WITKLHYAFQDKNNLYFVMDYYLGGDVLTLLSKFEDRLT
|.|....|.||||.|  |. |  ..|.||.|.. | .. .|.       ||... . ..   | ||||.||.|..|.|.|.|. ||. .. | |.. ...
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHL-KKKKKFS

EDMVKFYASEMILAIHSIHDL-GYVHRDIKPDNVLIGKDGHIRLADFG-SC-LKMDSNRKVNSTTAVGTPDYISPEILQAMEDGRGVYGPECDWWSLGIC
|....||.....||.   |.    . ||.||.| |...|||....||| |  ..|.... .. .. .||| |..||...        ..  .|||..|| 
EEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKA-YSFCGTPEYMAPEMITKK----KGHNKSVDWWAFGIF

IYEMLFGETPFYAESLLQTYSKIMQHKTLFSFPSDEDSIVVSKDAKNLIKN--LICDAEERLG--QSGIDDFKKHPFF
||||..| .|||...  | . ||  .   ..||   ... .|. .|.||.   |  . ..|||   .|... |.||.|
IYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFP---YPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase AqueK005.AA Pkinase 80-348 28 6.2e-71 246.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 80-348
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

FEVLEVIGRGAFGEVKVVRLKSTNKVYALKVLNKAEMLQRQTTACFK--EERDVLVFGNRDWITKLHYAFQDKNNLYFVMDYYLGG----DVLTLLS-KF
......||.|.||.|.  . |.|.|..|.|...| .    .  . ..  | .  . . | . | .|...|.||...|.||.|  ||    |  ...| . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

EDRL--TEDMVKFYASEMILAIHSIHDLGYVHRDIKPDNVLIGKDGHI----RLADFGSCLKMDSNRKVNSTTAVGTPDYISPEILQAMEDGRGVYGPEC
. ..  .|. .|||. ... ..  .|. | .|||.||.|.|| ..|||    ...|||.. ..|  ...  || .|||.|..||...    |.  |||..
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GGQYYGPKV

DWWSLGICIYEMLFGETPFYAE------SLLQTYSKIMQHKTLFSFPSD---------------EDSIVVSKDAKNLIKNLIC-DAEERLGQSGIDDFKK
|.||.|. .||||.|..||. .      . .| . .||. .. |..| .               .  . .|...| .||...| | ..|..   ... ..
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPT---AEQILQ

HPFF
||.|
HPWF
Kinase AqueK005.AA MAST 80-224 40 1e-55 177.93 In-house 1-144 (334) Show / Hide 
Range on Protein: 80-224
Range on HMM: 1-144/334
Sequence Identity: 40% (59 aa)

FEVLEVIGRGAFGEVKVVRLKSTNKVYALKVLNKAEMLQRQTTACFKEERDVLVFGNRDWITKLHYAFQDKNNLYFVMDYYLGGDVLTLLSKFEDRLTED
||  ..|..||.| |  |. |.||. .|.||..|..|. .  .   . ||..| .   ... |. |.|| ||.|..||.|  |||. .||. .  .. |.
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYG-YFDEW

MVKFYASEMILAIHSIHDLGYVHRDIKPDNVLIGKDGHIRLADFG
|.|.| .|..|..  .|  | ||||.||||.|| ..||| |.|||
MAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFG
Kinase AqueK005.AA MAST 80-224 38 1.4e-55 167.92 In-house 1-147 (337) Show / Hide 
Range on Protein: 80-224
Range on HMM: 1-147/337
Sequence Identity: 38% (57 aa)

FEVLEVIGRGAFGEVKVVRLKSTNKVYALKVLNKAEMLQRQTTACFKEERDVLVFGNRDWITKLHYAFQD--KNNLYFVMDYYLGGDVLTLLSKFEDRLT
|| ...|..||.| |  |. |.||. .|.||.|.  .. .      . ||..|..   ... |. |.||   |. |..||.|  |||. .||. .  .. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EDMVKFYASEMILAIHSIHDLGYVHRDIKPDNVLIGKDGHIRLADFG
|.|.|.|  | .|..  .|  | ||||.||||.|| ..||| |.|||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFG
Kinase AqueK005.AA NDR 240-348 42 3.8e-49 149.37 In-house 241-350 (350) Show / Hide 
Range on Protein: 240-348
Range on HMM: 241-350/350
Sequence Identity: 42% (48 aa)

AVGTPDYISPEILQAMEDGRGVYGPECDWWSLGICIYEMLFGETPFYAESLLQTYSKIMQHKTLFSFP--SDEDSIVVSKDAKNLIKNLIC-DAEERLGQ
.||||||. ||..|  . |   |...|||||||   ||||.| .||....   |. |||. |. .  |  ...  . .|..|..||..|.| |...||| 
TVGTPDYMAPEVFQQ-KTG---YNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGS

SG--IDDFKKHPFF
 |  .|..|.||||
HGKGVDEIKSHPFF
Kinase AqueK005.AA MAST 241-348 38 4.7e-33 97.84 In-house 229-337 (337) Show / Hide 
Range on Protein: 241-348
Range on HMM: 229-337/337
Sequence Identity: 38% (44 aa)

VGTPDYISPEILQAMEDGRGVYGPECDWWSLGICIYEMLFGETPFYAESLLQ-TYSKIMQHKTLFSFPSD---EDSIVVSKDAKNLIKNLI-CDAEERLG
.||||||.||..     |.| ||.  ||||.|| .|| | |..|| ...    . ..| .|.   ..|..   .|   .|..|. ||| |   .  .|||
CGTPDYIAPEVIL----GQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLG

QSGIDDFKKHPFF
  | |. |.||||
ANGADEIKQHPFF
Kinase AqueK005.AA MAST 241-348 35 4.6e-31 97.11 In-house 225-334 (334) Show / Hide 
Range on Protein: 241-348
Range on HMM: 225-334/334
Sequence Identity: 35% (41 aa)

VGTPDYISPEILQAMEDGRGVYGPECDWWSLGICIYEMLFGETPFYAESLLQTYSKIMQHK---TLFSFP-SDEDSIVVSKDAKNLIKNLI-CDAEERLG
.||||||.||..     |.| .|.  ||||.||..|| | | .||  ..   ....| ...   . . ..   .| .  |..|. ||..|  .| ..|||
CGTPDYIAPEVIL----GQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLG

QS-GIDDFKKHPFF
 . | |. |.||||
ANNGADEVKQHPFF
Kinase AqueK005.AA TyrKc 80-348 19 1.3e-11 -34.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 80-348
Range on HMM: 1-280/280
Sequence Identity: 19% (58 aa)

FEVLEVIGRGAFGEVKVVRLKSTNKVYALKVLNKAEMLQRQTTACFKEERDVL-VFG-NRDWITKLHYAFQDK-------NNLYFVMDYYLGGDVLTLLS
 . ....|.||||||   ..|      | |.|..         . | .|  ..  .| . . | .|. .  ..         |. || |  .|| .  | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KFEDRLTEDMVKFYASEMILAIHSIHDLGYVHRDIKPDNVLIGKDGHIRLADFGSCLKMDSN------RKVNSTTA-VGTPD-----YISPEILQAMEDG
| ...|. .    ..         .|. ...|||.   |.|.|...... .||| . . ..        .. ...   |. .       .|| .      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----N

RGVYGPECDWWSLGICIYEML-FGETPFYA-----ESLLQTYSKIMQHKTLFSFPSDEDSI----VVSKDAKNLIKNLICD-AEERLGQSGIDDFKKHPF
 |.. .. | || |.|..|.. .|..| .       |  . . ...| . .   |.|.  .      ..  . ..|      .|.|   | |     | .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI-----HEC

F
|
F
Kinase AqueK005.AA S_TK_X 349-409 24 1e-09 39.51 SMART 1-79 (79) Show / Hide 
Range on Protein: 349-409
Range on HMM: 1-79/79
Sequence Identity: 24% (22 aa)

EGIDWDNIRS----QTPPYIPEFT----SDTDTRNFE---PYEPDDPGHDPTPPNLTALTLHLP-------------------FVGFTFTS
 |||||....     .||..|. .    |.|||.||.   . |...            || . |                   | |||.  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM------------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase AqueK005.AA Pkinase_C 366-411 31 8e-06 23.87 Pfam 1-46 (46) Show / Hide 
Range on Protein: 366-411
Range on HMM: 1-46/46
Sequence Identity: 31% (15 aa)

EFTSDTDTRNFEPYEPDDPGHDP-TPPNLTALTLHLPFVGFTFTSGS
. .|.|||.||.| . | |  |   ...      ..||.|||... .
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
HALZ AqueK005.AA HALZ 441-460 40 0.660017 6.34 Pfam 26-45 (45) Show / Hide 
Range on Protein: 441-460
Range on HMM: 26-45/45
Sequence Identity: 40% (8 aa)

EEEERLRAEVKSLKDELDKS
.| . |.|||..||. | ..
KENQKLKAEVQRLKEKLQMK
HALZ AqueK005.AA HALZ 480-509 36 0.154105 8.5 Pfam 16-45 (45) Show / Hide 
Range on Protein: 480-509
Range on HMM: 16-45/45
Sequence Identity: 36% (11 aa)

TLERAVRSLKSEKNSLTEQVSDLKESLAAK
.| .  .||. |. .|  .|  ||| |  |
ALKHEYDSLQKENQKLKAEVQRLKEKLQMK
DMPK_coil AqueK005.AA DMPK_coil 492-540 26 6.918436 2.18 Pfam 13-61 (61) Show / Hide 
Range on Protein: 492-540
Range on HMM: 13-61/61
Sequence Identity: 26% (13 aa)

KNSLTEQVSDLKESLAAKEKELKEGNKRYRESQDELNRISDKMTDYRSQ
| |. |     |..  . |  |.|  |. || . |. ..   |   |..
KQSIHEELNKVKAANIQFECKLQEAEKKNRELEQEMEQLKKEMEMLRAR
HALZ AqueK005.AA HALZ 626-645 30 9.060039 2.45 Pfam 26-45 (45) Show / Hide 
Range on Protein: 626-645
Range on HMM: 26-45/45
Sequence Identity: 30% (6 aa)

QDTQELQKNIEKLQAQLQEK
.. |.|.. ...|...||.|
KENQKLKAEVQRLKEKLQMK
DMPK_coil AqueK005.AA DMPK_coil 629-641 38 14.28957 1.1 Pfam 49-61 (61) Show / Hide 
Range on Protein: 629-641
Range on HMM: 49-61/61
Sequence Identity: 38% (5 aa)

QELQKNIEKLQAQ
..|.| .| |.|.
EQLKKEMEMLRAR
DMPK_coil AqueK005.AA DMPK_coil 674-698 32 24.947092 0.27 Pfam 37-61 (61) Show / Hide 
Range on Protein: 674-698
Range on HMM: 37-61/61
Sequence Identity: 32% (8 aa)

SESTNTELHNENNDLQVRLTKVRNR
.|. | ||  |   |. ..   | |
AEKKNRELEQEMEQLKKEMEMLRAR
HALZ AqueK005.AA HALZ 662-674 61 34.802501 0.45 Pfam 33-45 (45) Show / Hide 
Range on Protein: 662-674
Range on HMM: 33-45/45
Sequence Identity: 61% (8 aa)

AEVQKLKELLATS
||||.||| | ..
AEVQRLKEKLQMK
HALZ AqueK005.AA HALZ 721-742 31 47.097679 0.0 Pfam 24-45 (45) Show / Hide 
Range on Protein: 721-742
Range on HMM: 24-45/45
Sequence Identity: 31% (7 aa)

LSEEKRELSLQVESLTTKLEES
| .|. .|  .|..|. ||...
LQKENQKLKAEVQRLKEKLQMK
DMPK_coil AqueK005.AA DMPK_coil 830-883 32 0.000203 17.71 Pfam 1-61 (61) Show / Hide 
Range on Protein: 830-883
Range on HMM: 1-61/61
Sequence Identity: 32% (20 aa)

EMQQNFENELRAKQRVEEELTHIRT-------QLAHTESDVVQLKAQIESLQKENEKLNKE
| |   | | |||| . |||. ...       .|  .|.    |....|.|.|| | |  .
ELQSALEAEIRAKQSIHEELNKVKAANIQFECKLQEAEKKNRELEQEMEQLKKEMEMLRAR
HALZ AqueK005.AA HALZ 865-894 43 0.026219 11.13 Pfam 16-45 (45) Show / Hide 
Range on Protein: 865-894
Range on HMM: 16-45/45
Sequence Identity: 43% (13 aa)

QLKAQIESLQKENEKLNKENQKYRMGLGSR
.||.. .||||||.|| .| |. .  |  .
ALKHEYDSLQKENQKLKAEVQRLKEKLQMK
C1_1 AqueK005.AA C1_1 934-986 34 2.6e-14 56.22 Pfam 1-55 (55) Show / Hide 
Range on Protein: 934-986
Range on HMM: 1-55/55
Sequence Identity: 34% (19 aa)

HELVVR-SFDSPTKCDACTSVMFG-LVRQGMMCKNCQMSCHVQCKDKVLATCPLP
|  |.. .|..||.|. | . ..| | .||. | .|.. || .|  || . |.. 
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 AqueK005.AA C1 934-983 29 3.7e-14 54.29 SMART 1-61 (61) Show / Hide 
Range on Protein: 934-983
Range on HMM: 1-61/61
Sequence Identity: 29% (18 aa)

HELVVRSFDSPTKCDACTSVMFGLVRQ-----GMMCKNCQMSCHVQCKDKVLA-------TC
|  . ..| .||.|. | . ..|. .|     |..| .|.. || .|.|||..       .|
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
PH AqueK005.AA PH 1004-1125 9 2.6e-11 44.8 SMART 1-82 (82) Show / Hide 
Range on Protein: 1004-1125
Range on HMM: 1-82/82
Sequence Identity: 9% (12 aa)

TACEGWIQVPKPGGVKKGWTRAYAFVCDFKIFCHEPSNDVHSPANGVFNIFDIRDINFRVSKVTRQDVIHAGEKLIPTIFKISCTHPTCSSVGILSELLI
. .|||. . .    | .|.. ......  .......            .....|. .|. .                 |.|.. .          ....
VIKEGWLYKKS----K-RWKKRWFVLFNDCLYYYKDK--------KPKGSIPLSDCTVRE-P----------------CFEIHH-DR---------TYYF

RTDNENERDKWVATLDELQKAA
....| |...|.. . .... .
QCESEEEMQEWMQAIQKAIHNN
PH AqueK005.AA PH 1004-1123 10 7.4e-10 38.19 Pfam 1-92 (92) Show / Hide 
Range on Protein: 1004-1123
Range on HMM: 1-92/92
Sequence Identity: 10% (12 aa)

TACEGWIQVPKPGGVKKGWTRAYAFVCDFKIFCHEPSNDVHSPANGVFNIFDIRDINFRVSKVTRQDVIHAGEKLIPTIFKISCTHPTCSSVGILSELLI
  .|||. . .    .|.| . ...... .........           .....|....  .              | .|.|.. ..         ....
VIKEGWLHKKG---KRKSWKKRWFVLFNNCLYYYKDDK------YRPKGSIPLSDCQVTKVPDN----------KRPHCFQIRT-DR--------RTYYF

RTDNENERDKWVATLDELQK
....| |.. |.. . ....
QAESEEEMNDWMQAIQSACR
CNH AqueK005.AA CNH 1155-1425 21 4.9e-58 203.92 Pfam 1-336 (336) Show / Hide 
Range on Protein: 1155-1425
Range on HMM: 1-336/336
Sequence Identity: 21% (75 aa)

SAAIANNDRILLG-AEDGLYMFDV-------ADEGLYQCGDKDLKRVIQLAVLQDEELVVIL--AGRRPTLRLLPTSALDSGEMRN--------------
....   ...|.| ...|||. ..        . ...|  ..   || |..|.... .....  ... ..|.. | ..||. |  .              
VCPCTWGQWLLVGTTDEGLYVYNIRNTRDCRHWTRICQKFSR---RVTQIYVIEEFNILIMISGCDKNKHLYVHPLDWLDQKEQQWHQCHNPKHRCTHRI

---------VVIDVTETKGAHLFCTGNLG--PTQYICVAIKN-----KVLIYELSRTKTRY-------------ERKKE-LVIS----GQVHSMSMV---
         . . . .||..|.||... |   . ..|.|.|.     ....||  ... ..             .  .| . |.      ..||..    
ERIMPRKFAMWQKLPDTKHCHFFCWIRNGYCNGRCLCCAVKRSGLHSTIKCYEWYHPMKKFHKQRSFKGNQEWFRKFRECFYIPLPPMTECFSMHWLPQE

NEKLCIGYLSGFSVFNVY-LDQPEISQYXLVNNDDLS--LGF-VRINELNAMCAVEINNGQ-EYLLCFHLVGIYVTNEGR-RSR--KQELLWHSTPTSIV
 .|||.|. .|| . |.    ||    . |.. .| |  ..|  |.  . . |...||. . |.|||..  ..||. .|. |||  ..|. | ..|.|..
KPKLCVGCQKGFHIVNLDGTGQP----WWLHDPADHSVQQDFMARRENCKPICMHRIND-DEEFLLCYDECCVYVNKQGWPRSRKHDWEIMWEGMPQSFA

HRQPYLLVFCESNLEVYNVETS-EW---TQTISIKKLQSISPGG
...||||.| .  .|. .|||. ||   .|.|. .... .  |.
CCYPYLLAFHPNFIEIRHVETGSEWDACVQCIPGQNIRFLHSGS
CNH AqueK005.AA CNH 1149-1433 16 6e-24 86.81 SMART 1-375 (375) Show / Hide 
Range on Protein: 1149-1433
Range on HMM: 1-375/375
Sequence Identity: 16% (64 aa)

LLKSVQSAAIANN---DRILLGAEDGLYMFDVADE-------GLYQCGDKDLKRVIQLAVLQDEELVVILAGRRPTLRLLPTSAL---------------
. ... .. .      . .|.|.|.|.|......        ....      ..| ...|. ...... ..|..| |. .| ..|               
CTMKWCHPITCDQLWGKWLLVGTEHGIYCLNINCQQNQDHEGTPEHI--HHRRCVTCMWVYEENNCLMMISGKKPHLYSHPLVWLFQKYRTQGMTPHIQD

-----DSGEMRNVV-IDVTETKG-AHLFCT-GNLGP--TQYICVAIKNKVLIY------ELSRTKTR--------------YERKKELVISGQVHSMSMV
     .. . .||. . . .||| .|..|  .|       ..|.| . .| ||      ...  . .                |..|.. .    . .  
HMCNHHLVPRKNVWTTKIPDTKGNCHHCCVKCNGKRTGIIFLCHAMQHSVQIYNQWYNPMHKFMCWKSSNNILNNEIEMFKHFRFPEIFPVPVFVCFHHD

NE---KLCIGYLS---GFSVFNVYLDQ--PEI----SQYXLVNNDDLSLGFVRIN-EL-----NAMCAVEINN--G---QEYLLCFHLVGIYVTNEG---
.    ..|||  .   |.. |.....   .       .  .||..|.|| |  .  ..     ...... ...  |    .||||..  |..|...|   
SFERPWICIGCDKPVGGMYGFHMVQHHQHCHCNSFNMHESTVNMNDHSLWFMNQQTSHQQDTCKPHQVHQVQQSDGGQRDMYLLCYDNFGVFVNCYGSEW

RRSRKQELLWHSTPTSIVHRQPYLLVFCESNLEVYNVETSEW-TQTIS------IKKLQSIS----PGGTIALCNSS
||.|...| |   |.. . ..||...| .  .......| || ||.|       ..|.  ..      ..| .| ..
RRWRNPILHWEFMPEYFAYHYPYIMAFWDNGIQIRHIKTGEWNTQCIMDRQYIKCRKFRLLCTCECRDRKIFYCSQP
RWD AqueK005.AA RWD 1418-1624 8 6.8e-05 20.62 Pfam 13-119 (119) Show / Hide 
Range on Protein: 1418-1624
Range on HMM: 13-119/119
Sequence Identity: 8% (18 aa)

LQSISPGGT------IALCNSSDSTCTVYIKSDSDSSSNILHVTSVNRRGTVITKSKKVVKPARPVISGPTEFAYVQHFGPHPQLDVETMQNAGEVARLR
|.|| |.        |  ...|....|. |   .. .|. ..                                                          
LESIYPDDFEDLRGTICWTEISPWHFTIKI---DECESSHHP----------------------------------------------------------

GASIPTLSMSQSTQSLSPRKDHHHSQILSSHHYKAGSIEHLPAAYQSIEYKNIIVNIQFPPEYP-ANPLLLQ-IKSKVLPD----KLIEKIETLCDQELK
                                                    .....|.|..||   | ... |..  .        |..... ......
---------------------------------------------------PLVLHFQCPEDYPSDEPPIISIISC-WNLHKLPDYQIQQLCKKLQEYWE

KLV-GSKQVSTILLFLCDFI
 .. |   . ..  .| ...
ENCHGMVMIFEWIEWLQENL
Zf-C3HC4 AqueK005.AA zf-C3HC4 1781-1810 20 1.7e-05 16.91 Pfam 17-48 (48) Show / Hide 
Range on Protein: 1781-1810
Range on HMM: 17-48/48
Sequence Identity: 20% (7 aa)

IYCGHL-----YHFQCLDSYMKTPPFTGGKKCVKC
..|||      ... |. .. ..    | ..|  |
HPCGHRGSLKWFCHSCIKRWWNH---SGNTQCPIC
RING AqueK005.AA RING 1753-1810 15 0.000248 19.59 SMART 1-23 (23) Show / Hide 
Range on Protein: 1753-1810
Range on HMM: 1-23/23
Sequence Identity: 15% (9 aa)

CPVCNKRALPTDPKDIIIDEGHPQYVYRIYCGHLYHFQCLDSYMKTPPFTGGKKCVKC
||.|                     .  . ||| ... |.              |  |
CPICLE-------------------PVVLPCGH-FCY-CI--------------CPIC