Gene AqueK008 (A.queenslandica)

AqueK008

Species: A.queenslandica
Alias: AqueK008
External Links:
Annotation:

Classification

Group: AGC
Family: GRK
Subfamily: GRK

Sequence

Name Sequence Type Origin Length Description Download
AqueK008.AA Protein None 497 None Fasta, JSON
AqueK008.kin_dom Protein Kinase Domain None 264 None Fasta, JSON

Protein domain

Protein domains of AqueK008.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RGS AqueK008.AA RGS 20-149 20 1.6e-17 65.46 SMART 1-121 (121) Show / Hide 
Range on Protein: 20-149
Range on HMM: 1-121/121
Sequence Identity: 20% (27 aa)

TFEFIVEQQPIGHKLFLLFCEKDLKL-SRCMQFLHAVDELKIVVEGKRLAHAQTVFDDFLSLDSP-QDQASKFLGAGKLEC--VSDELATKTQEKLKGIV
.|. . ...|||  .|  |...   . .....|. |..|.|   . .| . |.  .|...| ..| .            .|  ..... ...|. |.. .
SFHHLCDNDPIGRRYFREFLKQEFCEYKENLEFWLACEEFKKMEDEERRQKAREIYDKYISPNAPCE------------HCVNIDHHTREQCQQCLCN-P

PVDVFEECRQAVRDFLSGQPLIDFVESPFYWRFL
. |.|.|. ..|...... .  .|..|..| |.|
HPDCFDEAQRHVYQLMEKDSYPRFLRSDYYKRYL
RGS AqueK008.AA RGS 20-148 20 1e-08 30.79 Pfam 1-124 (124) Show / Hide 
Range on Protein: 20-148
Range on HMM: 1-124/124
Sequence Identity: 20% (27 aa)

TFEFIVEQQPIGHKLFLLFCEK-DLKLSRCMQFLHAVDELKIV---VEGKRLAH-AQTVFDDFLSLDSPQDQASKFLGAGKLECVSDELATKTQEKLKG-
.|. . . |||| .||  |.|.    . ....|. |. ..|      . |...  |.  .. ... |||  . .         ...... ...|..|.  
SFHHLCNDQPIGRRLFRQFLESEFCEY-ENIEFWLACEDFKKMFSDSDEKMHQKDAREIYNKYIAPDSP-CECH---------NIDHDTREHCQDNLEQA

IVPVDVFEECRQAVRDFLSGQPLIDFVESPFYWRF
 .  |.|.|. . . ..... .   |..|..| ||
QPTPDCFDEAQRHIYTLMEKDSYPRFLKSDYYQRF
Kinase AqueK008.AA GRK 164-427 61 4.1e-190 604.79 In-house 1-272 (272) Show / Hide 
Range on Protein: 164-427
Range on HMM: 1-272/272
Sequence Identity: 61% (168 aa)

FRQYRVLGKGGFGLVFACQSKFTGKMYALKKLEKKRVKKRKGEKLALNEKEVLEKVDSR---FVVTLAYAYQSKDSLCMVLTLMNGGDLRFHIYSIGS--
||||||||||||| | ||| . ||||||.|.|.|||.||||||..|||||..|||| ||   |.| .||||..|| ||.|.|.||||||..||| .|.  
FRQYRVLGKGGFGEVCACQVRATGKMYACKCLDKKRIKKRKGETMALNEKQILEKVHSRDCPFIVCMAYAYETKDALCLVMTIMNGGDLHYHIYNMGNNE

PGLEPERVVFYAAEIACGLHHLHTARIAYRDMKPDNILLDDAGHIRISDLGLAVHIPEGQ-SVRGRVGTPGYMAPEVIDGHR-YTFAPDWWGMGCLIYEM
||.. ||..||||||.||| |.|  || |||.|| |||||| ||.||||||||..|||||  ..|||||.|||||||... | |.| ||||..||.||||
PGFDEERMRFYAAEICCGLEHMHRRRIVYRDLKPENILLDDHGHVRISDLGLACEIPEGQPMIHGRVGTHGYMAPEVLQNERAYDFSPDWWSLGCMIYEM

ICGRTPFRKHKERVSREDIERRIKDDRVCLDNSAFTEDSRSICDQFLDKVHATRLGCCGEMF--EDVKAHPFF
| |..|||.||| |.||...||.| | | .  . |.|....|| ..| |  . |||| |.    ..||.||||
IEGHSPFRQHKEKVKREEVDRRVKEDPVKYP-DKFSEEAKDICEMLLQKDPEQRLGCRGGTCGAQEVKEHPFF
Kinase AqueK008.AA GRK 164-427 67 1.8e-184 619.17 In-house 1-265 (265) Show / Hide 
Range on Protein: 164-427
Range on HMM: 1-265/265
Sequence Identity: 67% (179 aa)

FRQYRVLGKGGFGLVFACQSKFTGKMYALKKLEKKRVKKRKGEKLALNEKEVLEKVDSRFVVTLAYAYQSKDSLCMVLTLMNGGDLRFHIYSIG-SPGLE
||||||||||||| | ||| . ||||||.|||||||.||||||..|||||..|||| ||||| ||||| .|| || |.|.||||||.|||| .| .||..
FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEQMALNEKQILEKVHSRFVVSLAYAYETKDALCLVMTIMNGGDLKFHIYNMGENPGFD

PERVVFYAAEIACGLHHLHTARIAYRDMKPDNILLDDAGHIRISDLGLAVHIPEGQSVRGRVGTPGYMAPEVIDGHRYTFAPDWWGMGCLIYEMICGRTP
 ||..||||||.||| |||  || |||||| |||||| ||||||||||||.||||| .||||||.|||||||... |||| |||||.|||||||| ||.|
EERAIFYAAEICCGLEHLHRERIVYRDMKPENILLDDHGHIRISDLGLAVEIPEGQMIRGRVGTVGYMAPEVVKNERYTFSPDWWGLGCLIYEMIEGRSP

FRKHKERVSREDIERRIKDDRVCLDNSAFTEDSRSICDQFLDKVHATRLGCCGEMFEDVKAHPFF
||. || |.||...||.|.| .    . |.|....|| ..| |  . |||| .|  ..|..||||
FRQRKEKVKREEVDRRVKEDPEKYSHEKFSEEAKDICRMLLHKDPEQRLGCREEGCDEVRQHPFF
Kinase AqueK008.AA AGC 164-427 25 1.6e-136 355.25 In-house 1-395 (395) Show / Hide 
Range on Protein: 164-427
Range on HMM: 1-395/395
Sequence Identity: 25% (100 aa)

FRQYRVLGKGGFGLVFACQSK------FTGKMYALKKLEKKR-VKKRK--GEKLALNE------------KEVLEKVD----------SRFVVT-LAYAY
|. ..|.|||.|| |. .. |       |||.||.|.|.||. ....|   .. ...|            ...|||..          . |.|  | |..
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QSKDS--LCMVLTLMN--------GGDLRFHIYSI---GSPGLEPERVVFYAAE-------IACGLHHLHT-ARIAYRD-MKPDNILLDDAGHIRISDLG
|.||   |..|. .|.        ||.. ....     ..  .. ||. |||||       |...|..||    | .|| .||.|||||. |||...| |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAVHIP---------------------------------------------------EGQSVRGRVG--TPGYMAPEVIDGHRYTFAPDWWG--MGCLIY
|.  ..                                                   ...     .|  || |||||..    |..| |||.  .|||.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMICGRTPFRK-------HKERVSREDIERRIK------DDRVCLDN---------SAFTEDSRSICDQFLDKVHATRLGCCGEM-----FEDVKAHPFF
||..|..||.        | .. .....  .|.       ..| ...         . |... .... ..| |  . |||| |.      .|..|.||.|
EMLTGYPPFYGDNPQENRH-PFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase AqueK008.AA S_TKc 164-427 30 3.7e-83 283.51 SMART 1-231 (231) Show / Hide 
Range on Protein: 164-427
Range on HMM: 1-231/231
Sequence Identity: 30% (84 aa)

FRQYRVLGKGGFGLVFACQSKFTGKMYALKKLEKKRVKKRKGEKLALNEKEVLEKVDSRFVVTLAYAYQSKDSLCMVLTLMNG--GDLRFHIYSIGSPG-
..  |..|||.|| |. |. | ||. .|.|..           . ...| ..|.| .  ..|.| ...|. |.|.||. ...|  |||. .| . |..| 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LEPERVVFYAAEIACGLHHLHTARIAYRDMKPDNILLDDAGHIRISDLGLAVHIPEGQSVRGRVGTPGYMAPEVIDGHRYTF-APDWWGMGCLIYEM
   . . .. ||...|.|.| ..|  .| .|| ||.|||||.  || |.| ||| ..      .  .||| ||||||.    |.. . |||  ||..|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

ICGRTPFRKHKERVSREDIERRIKDDRVCLDNSAFTEDSRSICDQFLDKVHATRLGCCGEMF--EDVKAHPFF
.||..||.        . . ..|.           ... ... .. |.|  . |...   .   .|.|.||.|
LCGYPPFP------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK008.AA BARK 164-427 44 2.7e-82 279.73 In-house 1-264 (264) Show / Hide 
Range on Protein: 164-427
Range on HMM: 1-264/264
Sequence Identity: 44% (119 aa)

FRQYRVLGKGGFGLVFACQSKFTGKMYALKKLEKKRVKKRKGEKLALNEKEVLEKVDSR----FVVTLAYAYQSKDSLCMVLTLMNGGDLRFHIYSIGSP
|   |..|.|||| |. |    ||||||.| |.|||.| ..|| |||||. .|. |       |.| ..||... | || .| ||||||| .|.   |  
FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGQDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGV-

GLEPERVVFYAAEIACGLHHLHTARIAYRDMKPDNILLDDAGHIRISDLGLAVHIPEGQSVRGRVGTPGYMAPEVID-GHRYTFAPDWWGMGCLIYEMIC
    . . ||||||  || |.|.  . |||.|| |||||. ||.||||||||    . .     ||| |||||||.  |  |  . ||. .||..| .. 
-FSEQEMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDENGHVRISDLGLACDFSK-KKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLYKLLR

GRTPFRKHKERVSREDIERRIKDDRVCLDNSAFTEDSRSICDQFLDKVHATRLGCCGEMFEDVKAHPFF
|  |||.|| .  .| |.|      | |   .| .. |.. .  | .  . |||| |.  ..|| ||||
GHSPFRQHKTKDKHE-IDRMTLTMNVELP-DSFSKEMRDLLEGLLQRDVSKRLGCMGRGAQEVKEHPFF
Kinase AqueK008.AA RSK 167-427 32 5.8e-71 242.06 In-house 1-278 (278) Show / Hide 
Range on Protein: 167-427
Range on HMM: 1-278/278
Sequence Identity: 32% (91 aa)

YRVLGKGGFGLVFACQSK---FTGKMYALKKLEK-KRVKKRKGEKLALNEKEVLEKVD-SRFVVTLAYAYQSKDSLCMVLTLMNGGDLRFHIYSIGSPG-
 .|||.||.| || |. .    ||. || | |.| |.|.. |  . .. | ..|| .  . |.||| ||.| .. | ... ...||.|  |..  .. | 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LEPERVVFYAAEIACGLHHLHTARIAYRDMKPDNILLDD---AGHIRISDLGLAVH-IPE-GQSVRGRVGTPGYMAPEVID---GHR-YTFAPDWWGMGC
.  ... ||.|||.. . |||.  | .|| ||.|||.||    |||...| |..    .. .|     ..|  |||||..    . . .. | |||  |.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LIYEMICGRTPFRKHKERVSREDIERRIKDDR--VCLD-NSAFTEDSRSICDQFLDKVHATRLGCCGEMFEDVKAHPFF
|.|||  |..||.   .. .|..| .||.  .  . .. ..  ... ...  . | .  . ||||  .  |..|.||.|
LMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase AqueK008.AA Pkinase 164-427 28 2.5e-67 234.78 Pfam 1-293 (293) Show / Hide 
Range on Protein: 164-427
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

FRQYRVLGKGGFGLVFACQSKFTGKMYALKKLEKKRVKKRKGEKLAL-NEKEVLEKVDSRFVVTLAYAYQSKDSLCMVLTLMNGG----DLRFHIYSIGS
..  |..|.|.|| |. |. | |||..|.|...|.. |. | . ... .| ... .... ..|.| .....||...||. ...||    ||  .|    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PGL--EPERVVFYAAEIACGLHHLHTARIAYRDMKPDNILLDDAGHI----RISDLGLAVH--IPEGQSVRGRVGTPGYMAPEVID-GHRYTFAPDWWGM
 ..  ... . ||. .|..|| ..|  .| .||.||.|||.|. |||    .|.| ||| .  .  ..   ...|||.|||||||  |  |. . |.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCLIYEMICGRTPFRKHK----ERVSREDIERRIKDDRVCLDNSAFT--------------------EDSRSICDQFLDKVHATRLGCCGEMFEDVKAHP
||..|||.|||.||. ..    . ..   . .||.. ..  | .                       |. .....  |.|  . |..     .|... ||
GCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHP

FF
.|
WF
Kinase AqueK008.AA PKC 164-427 36 3.5e-67 216.75 In-house 1-262 (262) Show / Hide 
Range on Protein: 164-427
Range on HMM: 1-262/262
Sequence Identity: 36% (98 aa)

FRQYRVLGKGGFGLVFACQSKFTGKMYALKKLEKKRVKKRKGEKLALNEKEVLEKVDSR-FVVTLAYAYQSKDSLCMVLTLMNGGDLRFHIYSIGSPGLE
|.  .||||| || |.   .| | ..|| | | |  . .      ...|| ||.      | . |    |..| |  |.   ||||| ||| ...   ..
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRR--FK

PERVVFYAAEIACGLHHLHTARIAYRDMKPDNILLDDAGHIRISDLGLA-VHIPEGQSVRGRVGTPGYMAPEVIDGHRYTFAPDWWGMGCLIYEMICGRT
 |. .||||||.|.|. ||.  | ||| | ||.|||  |||.| | |..  .. .|.  .   ||| |.|||.. .  |... ||| .| | ||| .|. 
EEHARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQS

PFRKHKERVSREDIERRIKDDRVCLDNSAFTEDSRSICDQFLDKVHATRLGCCGEM---FEDVKAHPFF
||    |    ... . | .|..    . ..... ||| .|..|  ..||||  .    ..|...||||
PFHGEDE----DELFQSIMHDNPHYPRW-LSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase AqueK008.AA Akt 164-363 40 1.7e-65 208.31 In-house 1-203 (264) Show / Hide 
Range on Protein: 164-363
Range on HMM: 1-203/264
Sequence Identity: 40% (83 aa)

FRQYRVLGKGGFGLVFACQSKFTGKMY-ALKKLEKKRVKKRKGEKLALNEKEVLEKVDSRFVVTLAYAYQSKDSLCMVLTLMNGGDLRFHIYSIGSPGLE
|.  .||||| || || .. | |.|.| |.| | |..  ...  . .. |. .|..... |.| | |. |..| |..|.  .|||.| .|..    .   
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQR--KRRFS

PERVVFYAAEIACGLHHLHTARIAYRD-MKPDNILLDDAGHIRISDLGLAV-H-IPEGQSVRGRVGTPGYMAPEVIDGHRYTFAPDWWG-MGCLIYEMIC
 .|  ||.||| ... |||   | ||| .|| |||.|  |||.. | ||.  . | ...      ||| |.|||...|. .| | ||||  ||..|||.|
EDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMC

GRTPF
|| ||
GRPPF
Kinase AqueK008.AA SGK 164-363 35 8.1e-63 192.64 In-house 1-225 (283) Show / Hide 
Range on Protein: 164-363
Range on HMM: 1-225/283
Sequence Identity: 35% (80 aa)

FRQYRVLGKGGFGLVFACQSKFT------------------GKMYALKKLEKKRVK-------KRKGEKLALNEK-EVLEKVDSRFVVTLAYAYQSKDSL
|.   |.|||.|| |.  . | .                  .|.||.| | |. .        |.| .|. . |.  .| .. . | | | || | |. |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

CMVLTLMNGGDLRFHIYSIGSPGLEPERVVFYAAEIACGLHHLHTARIAYRDMKPDNILLDDAGHIRISDLGLAV-HIPEGQSVRGRVGTPGYMAPEVID
 .|.  .|||.. .|.   ..  .   |. ||||||.| | .||   | ||| ||.|||||. ||... | ||.   | . .      ||| |.||||. 
YFVMDYVNGGEMFYHLQREKH--FPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLR

GHRYTFAPDWWGMGCLIYEMICGRTPF
.. .  . ||| .||. |||. |  ||
KQPHDRTVDWWCLGCVLYEMMYGLPPF
Kinase AqueK008.AA Delta 164-427 34 1.4e-60 207.58 In-house 1-259 (259) Show / Hide 
Range on Protein: 164-427
Range on HMM: 1-259/259
Sequence Identity: 34% (93 aa)

FRQYRVLGKGGFGLVFACQSKFTGKMYALKKLEKKRVKKRKGEKLALNEKEVLE-KVDSRFVVTLAYAYQSKDSLCMVLTLMNGGDLRFHIYSIGSPGLE
|   .||||| || |.    | . | ||.| | |  | .       . |. ||   ... |.  |  ..|.|. |  |.  .||||| .|| ...    .
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHR--FD

PERVVFYAAEIACGLHHLHTARIAYRDMKPDNILLDDAGHIRISDLGLA-VHIPEGQSVRGRVGTPGYMAPEVIDGHRYTFAPDWWGMGCLIYEMICGRT
 .|  |||.|| |||. ||.  | |||.| ||.|||  |||.| | |..  ..   .      ||| |.|||.| |..|... |||  | |.|||. |  
EKRARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQS

PFRKHKERVSREDIERRIKDDRVCLDNSAFTEDSRSICDQFLDKVHATRLGCCGEMFEDVKAHPFF
||  . |    ... . |  ||        |......  . ...   .|||       |...|.||
PFHGEDE----DELFWSICNDRPWYPR-WITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase AqueK008.AA AktR 164-427 32 2.9e-57 196.56 In-house 1-268 (268) Show / Hide 
Range on Protein: 164-427
Range on HMM: 1-268/268
Sequence Identity: 32% (90 aa)

FRQYRVLGKGGFGLVFACQSK-FTGKMYALKKLEKKRVKKRKGEKLALNEKEVLE-KVDSRFVVTLAYAYQSKDSLCMVLTLMNGGDLRFHIYSIGSPGL
|. |..||||.|| |. .| |  ..|.||.| . ||  ..|. .. ...|. ..| ...  | | | |. |.|. |  ..  . ||.| .|. ...   .
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKK--F

EPERVVFYAAEIACGLHHLHTA-RIAYRDMKPDNILLDDAGHIRISDLGLAV------HIPEGQSVRGRVGTPGYMAPEVIDG-HRYTFAPDWWGMGCLI
. |.. ||.|.|  .| .||    | |||.||.|||||  ||..|.| ||.         .. .|.   .||| |||||.|     .... |||  |..|
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSF---CGTPEYMAPEMITKKKGHNKSVDWWAFGIFI

YEMICGRTPFRK--HKERVSREDIER--RIKDDRVCLDNSAFTEDSRSICD-QFLDKVHATRLGCCGEMFEDVKAHPFF
|||. | .||    ... . ...|..  ....      .| |..  ....  . |.|    |||   . .|..| ||.|
YEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPY------PSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase AqueK008.AA TyrKc 164-417 19 1.1e-12 -17.59 SMART 1-280 (280) Show / Hide 
Range on Protein: 164-417
Range on HMM: 1-280/280
Sequence Identity: 19% (56 aa)

FRQYRVLGKGGFGLVFACQSKFTGKMYALKKLEKKRVKKRKGEKLALNEKEVLEKV--DSRFVVTLAYAYQSK-------DSLCMVLTLMNGGDLRFHIY
 .  ..|| | || |. .. |    . | |.| .        ..  ..| ... |.  .   .| |  .  ..       . |..|. .| .|||. .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SIGSPGLEPERVVFYAAEIACGLHHLHTARIAYRDMKPDNILLDDAGHIRISDLGLAVHIPEG-------QSVRGRV--GTPG-----YMAPEVIDGHRY
. .   | ..  . ..  ||||  .||  ..  ||    |.|... ....||| ||.  | ..       .  | .   |. .      ||||.|. ...
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TFAPDWWGMGCLIYEMI-CGRTPFRK---HKERVSREDIERRIKDDRVCLDNSA--------FTEDSRSICDQFLDKVHATRLG---CCGEM
|.. | |  | ...|.   | .|      .   .| ... ...|. .                ...  .|  |  .   . |     .. ..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK008.AA S_TK_X 428-484 18 2e-05 23.26 SMART 1-79 (79) Show / Hide 
Range on Protein: 428-484
Range on HMM: 1-79/79
Sequence Identity: 18% (15 aa)

QTIDFAHLEA--GLIPPPFIPNSRAVYAKDVLDIDQFS--SVRGVEIEKADED-------------------FADKFATG
  ||. .|..  . |.|||.|. ..||| .  |. .|     ...  .. |..                   |.. ..  
RGIDWDKLYNQQKEIEPPFKPKIKEVYA-SPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase AqueK008.AA SGK 391-427 31 0.000181 9.2 In-house 248-283 (283) Show / Hide 
Range on Protein: 391-427
Range on HMM: 248-283/283
Sequence Identity: 31% (12 aa)

FTEDSRSICDQFLDKVHATRLGCC-GEMFEDVKAHPFF
.. | ...  . | |    |||   .  |...| ||||
MSNDAWDLIQGLLQKDPKKRLGTKRD--FMEIKNHPFF
Kinase AqueK008.AA Akt 419-427 44 0.00317 6.07 In-house 256-264 (264) Show / Hide 
Range on Protein: 419-427
Range on HMM: 256-264/264
Sequence Identity: 44% (4 aa)

EDVKAHPFF
...|.||.|
QEIKRHPWF
Kinase AqueK008.AA Pkinase_Tyr 330-363 36 0.065631 7.09 Pfam 181-216 (270) Show / Hide 
Range on Protein: 330-363
Range on HMM: 181-216/270
Sequence Identity: 36% (13 aa)

MAPEVIDGHRYTFAPDWWGMGCLIYEMIC-GRTP-F
||||.|   ..| . | |  | |..|..  |..| .
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTY
Kinase AqueK008.AA Pkinase_Tyr 294-311 38 0.130415 6.08 Pfam 141-158 (270) Show / Hide 
Range on Protein: 294-311
Range on HMM: 141-158/270
Sequence Identity: 38% (7 aa)

NILLDDAGHIRISDLGLA
|.|... ....|.| |||
NCLVTENNVVKICDFGLA
Kinase AqueK008.AA Pkinase_Tyr 164-281 20 2.817645 1.56 Pfam 1-128 (270) Show / Hide 
Range on Protein: 164-281
Range on HMM: 1-128/270
Sequence Identity: 20% (26 aa)

FRQYRVLGKGGFGLVFACQSK----FTGKMYALKKLEKKRVKKRK--GEKLALNEKEVLEKV-DSRFVVTLAYAYQ-SKDS--LCMVLTLMNGGDLRFHI
 .  ..||.| || |. .  |     |.   | |.| |    ..    |..   | ... .  .   .| |  .    ...  ...|. .| .|||. . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

YSI--GSPGLEPERVVFYAAEIACGLHHLH
 .   . . | ... . ....||.|. .|.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLE