AqueK009

Species: A.queenslandica
Alias: AqueK009
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
AqueK009.AA Protein None 1368 None Fasta, JSON
AqueK009.kin_dom Protein Kinase Domain None 277 None Fasta, JSON

Protein domain

Protein domains of AqueK009.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DUF1908 AqueK009.AA DUF1908 181-279 34 6e-06 22.05 Pfam 1-96 (369) Show / Hide
Range on Protein: 181-279
Range on HMM: 1-96/369
Sequence Identity: 34% (38 aa)

PCGSPR-TWSPSITNFERF----SHGRRSEMRNDMRRWSLVSQ-SSGYTTYTSATDSPASLSSY-PSQEHI----HAPQDHTNNQLPTTPTPEDFAKLRK
|  |||   ..|  ||  |    ... ... | | ||||. |  |||| | .       ..||   |||      |        |||  || .| . | |
PIDSPRNFSTSSMMNFP-FVPIRRITNCRD-RADGRRWSVASLPSSGYGTNPPS----SNVSSQCSSQERLNQLPH--------QLPFQPTQDDLHFLSK

HFRSDSSGSS
||..  |  |
HFCCTESNPS

DUF1908 AqueK009.AA DUF1908 290-434 33 2.4e-28 103.14 Pfam 181-330 (369) Show / Hide
Range on Protein: 290-434
Range on HMM: 181-330/369
Sequence Identity: 33% (51 aa)

ATHRLRARSL-SPERSPRE--SLLDLDDTHAIFREKYPRAKLEMENQLVTFMNEFS---ETNRQFSDSNVNFARHQILEFARELLFKSQNDLLSKEVFIQ
. ||.| ||| ||.||.    .   .  .  ...| .|.|   || .|. |...|.   ..  . .|  | | .||..| ||  | ||.. |     |. 
PHHRPRSRSLSSPSRSCITFDNEIVMMNH--VYKERFPKATQQMEERLQHFIHHFKNIPCDSLRLADPVVRFIHHQVVEMARDCLHKSHAKLITSRYFYE

FSENVLQAVTNVRERN-GAESPELNQLVRKLLTVISRVARLVEIIEFDPNAF
 .|.  .   . .||   .| |.......||| .||| ||| |  ||||  |
MQEKLERLLHEAHERSESEEVPFITHVIKKLLIIISRPARLLECLEFDPEEF

Kinase AqueK009.AA MAST 511-787 44 2.4e-169 522.06 In-house 1-337 (337) Show / Hide
Range on Protein: 511-787
Range on HMM: 1-337/337
Sequence Identity: 44% (152 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSENPFVVGLWCTFQT--RQHLYMVMEYVEGGDVAALLKGVG-YLT
|. ||.||.|||||||||.|| |. |||||. |.  .| |.||..|| ||.|||. .||||| . ..|||  ...|.|||||.||||.| ||. .|  . 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

LELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTNYAAHVIED---------------AWAKDYQFV-------------
 ..| ||. ||||.|||.||.||.||||||||.||.| ||||||||||||.|... .  ..|.                  |.||               
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN

------------------------DQEVYGTPDYIAPEVILGMP-YGFPVDWWSMGVILYEMMMGVTPFVSSTIQD-LFEEITNENLHISFPEE------
                        .. ..||||||||||||| . || ||||||||.|.||   |..||. .| .  .|. |.| . .|..|||      
QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD

DEIPDDAQDLVRQLMCFDPMYRLGSTAREGVSGVKSHPFF
|.....||||...|   .|  |||  |. |.  .|.||||
DCMSPEAQDLIKKLLQPNPKKRLG--AN-GADEIKQHPFF

Kinase AqueK009.AA AGC 511-787 29 3.7e-159 415.12 In-house 1-395 (395) Show / Hide
Range on Protein: 511-787
Range on HMM: 1-395/395
Sequence Identity: 29% (118 aa)

FDVIKIISNGAYGAVYLVRHK------QTRMRFAMKKVNKKR-MIMKK--QVQSVFNE------------RDILTFSE----------NPFVVG-LWCTF
|...|.|. |..| |||||.|      .|   .|||...||. ...||  .|. . .|            |.||.             .||.|  |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTRQH--LYMVMEYVE---------GG-DVAALLK---GVGYLTLELATMYFSE-------TVLALEYIHS-HGIIHRD-LKPDNLLITSEGHIKLTDFG
|. .|  ||.||||..         || .    |.   . |... | |  |..|       .||||||.|| .|||||| |||.|.|....|||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKIGLTNYAA-------------------------HVIEDAWAKDYQ------------FVDQEVYG--TPDYIAPEVILGMPYGFPVDWWS--MGVIL
|.|.| ...                           . .. . ... .            .  .   |  ||.|.|||..    ||...||||  .|...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNK-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLM

YEMMMGVTPFVSSTIQ----------DLFEEIT------NENLHISFP------EEDEIPDDAQDLVRQLMCFDPMYRLGSTARE----GVSGVKSHPFF
|||. | .|| . . |          ..|. |       |..... ||      |.... ..|.||...|.| ||  |||.  .     |.. .|.||.|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF





Kinase AqueK009.AA MAST 511-787 44 5.9e-159 516.32 In-house 1-334 (334) Show / Hide
Range on Protein: 511-787
Range on HMM: 1-334/334
Sequence Identity: 44% (150 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSENPFVVGLWCTFQTRQHLYMVMEYVEGGDVAALLKGVGYLTLEL
|. ||.||.||||.||||.|| |. |||||...|  || |..|..|. ||.||....||||| . ..|||...|.|||||.||||.| ||. .||.  ..
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTNYAAHVIED----------------AWAKDYQFV---------------
| ||..||||.|||.|||||.||||||||.||.|.||||||||||||.|... .  ..|.                   .. ||.               
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

--------------------DQEVYGTPDYIAPEVILGMP-YGFPVDWWSMGVILYEMMMGVTPFVSSTIQDLFEEITNENLH-ISFPEE------DEIP
                    .. ..||||||||||||| . .| ||||||||.|.|| . |..||. .| . .|. |.|.|   |..||.      ....
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

DDAQDLVRQLMCFDPMYRLGSTAREGVSGVKSHPFF
 .||||...|   ||  |||  |. |.  ||.||||
PEAQDLIEKLLQPDPRKRLG--ANNGADEVKQHPFF

Kinase AqueK009.AA S_TKc 511-787 34 9e-93 315.43 SMART 1-231 (231) Show / Hide
Range on Protein: 511-787
Range on HMM: 1-231/231
Sequence Identity: 34% (99 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSENPFVVGLWCTFQTRQHLYMVMEYVEG--GDVAALLKGVGY---
......|  ||.| ||..||| |  ..|.|...          ... .|..||     |..| |  .||. .||||||||..|  ||.  ..|  |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTLELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTNYAAHVIEDAWAKDYQFVDQEVYGTPDYIAPEVILGMPYGF
   ..   |  |. ....||||.||||||||||||.|.|...  |||..||||...                        . |||.|.||||.   .||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------------TTFCGTPWYMAPEVL---GYGK

-PVDWWSMGVILYEMMMGVTPFVSSTIQDLFEEITNENLHISFPEEDEIPDDAQDLVRQLMCFDPMYRLGSTAREGVS---GVKSHPFF
 ..|||| |.|||||. | .||   ..| .|. |               ...| |..|.....||  |.  || |       .|.||.|
CKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRP--TA-EALQDEWDIKCHPWF

Kinase AqueK009.AA AktR 511-787 36 4.3e-90 305.62 In-house 1-268 (268) Show / Hide
Range on Protein: 511-787
Range on HMM: 1-268/268
Sequence Identity: 36% (105 aa)

FDVIKIISNGAYGAVYLVRHK-QTRMRFAMKKVNKKRMIMKKQVQSVFNERDILT-FSENPFVVGLWCTFQTRQHLYMVMEYVEGGDVAALLKGVGYLTL
|.|.|.. .||.| ||||..| ..   .||| . || .| ..| . . .||.|.   . .|| | |  .|||. .|. .|||..||.    ||  . .. 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

ELATMYFSETVLALEYIHSH-GIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTNYAAHVIEDAWAKDYQFVDQE------VYGTPDYIAPEVILG-MPY
| |  ||.. .||||| |.|  || |||||.|.|. ..||.|.|||||||                   ||.. .      ..||| |.|||.|.   ..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK------------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGH

GFPVDWWSMGVILYEMMMGVTPFVSSTIQDLFEEITNENLHISFPEEDEIPDDAQDLVR-QLMCFDPMYRLGSTAREGVSGVKSHPFF
...||||. |. .|||..| .|| ..  ...|. | ...  ..||.  .. . ..||.  .|.| .|  |||. ...| . .||||.|
NKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGY-YCNGWEEIKSHPWF

Kinase AqueK009.AA RSK-Unclassified 511-787 35 6.1e-88 276.27 In-house 1-283 (283) Show / Hide
Range on Protein: 511-787
Range on HMM: 1-283/283
Sequence Identity: 35% (102 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSENPFVVGLWCTFQTRQHLYMVMEYVEGGDVAALLK--GVGYLTL
| ... |  |  | ||||| |.| . .|||  .|..|| .. .. |  |..|.  .. ||.| |   |||.  ||..|||  |||    |       .. 
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

ELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSKIG-------LTNYAAHVIEDAWAKDYQFVDQEVYGTPDYIAPEVILGMPYG
... .| ||...|||| |  ..| ||||||| .   |||..||||.||. .       .   |   . |    |  |  .   || .|.|||.| .   .
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

FPVDWWSMGVILYEMMMGVTPFVSSTIQDLFEEITNENLHISFPEEDEIPDDAQDLVRQLMCFDPMYRLGSTAREG-VSGVKSHPFF
  |||| .|...|||..|..|.       .|. |  |  |..||.. .|  ...||.. |.   |  |||.    |    .| ||||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNI--EKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGC--KMGDADDIKRHPFF

Kinase AqueK009.AA RSK 514-787 33 4.8e-87 295.48 In-house 1-278 (278) Show / Hide
Range on Protein: 514-787
Range on HMM: 1-278/278
Sequence Identity: 33% (98 aa)

IKIISNGAYGAVYLVRHK---QTRMRFAMKKVNKKRMIMKKQ--VQSVFNERDILTFSE-NPFVVGLWCTFQTRQHLYMVMEYVEGGDVAALLKGVGY--
.|    |.||.|.|.| .   .|.. .|| || ||..|...|  .  .. ||.||  ..  ||.| |  .||| ..||..|||..||.    |.  ..  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAM-KVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-LTLELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITS---EGHIKLTDFGLSKIGLTNYAAHVIE-DAWAKDYQFVDQEVYGTPDYIAPEVIL---G
 .. . | .|..| |||.|..|..|||||||||.| | ..   ||||||||||..|..       ...   |..          .| .|.|||..    .
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------RCDHNQWTMT-------FCYTIEYMAPEMLKRANQ

MP-YGFPVDWWSMGVILYEMMMGVTPFVS---STIQDLFEEITNENLHISFPEEDEIPDDAQDLVRQLMCFDPMYRLGSTAREGVSGVKSHPFF
   ..  .|||| ||..||| .| .|| .   .. ..... | . ..  ..|. ... ..|.||.|.... ||  |||.  ..... .|.||.|
QGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGC-GPQDAEEIKQHPWF

Kinase AqueK009.AA Ciliate-E2 511-787 23 3.2e-81 276.13 In-house 1-365 (365) Show / Hide
Range on Protein: 511-787
Range on HMM: 1-365/365
Sequence Identity: 23% (92 aa)

FDVIKIISNGAYGAVYLVRHKQTR-----------------------MRFAMKKVNKKRMIMKKQVQSVF----------NERDILTFSENPFVVGLWCT
...||.| .|..| ||........                       . .||| ..|.  ...||.....          ||. || .  .|... .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TRQHLYMVMEYVEGGDVAALLK-------------------GVGYLTLELAT-------MYFSETVLALEYIHSHG-IIHRDLKPDNLLITSEGHI
||  .....|.||||..|||   ..|                    ..|.. ...        .|. . .|||||.|| . |||||.||.|.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGLSKIGLTNYAAHVIEDAWAKDYQFVDQE-------------------VYGTPDYIAPEVILGMP---------YGFPVDWWSMGVILYEMMMGV
|..||||||.  ...  . .    .| |.|  ..                   ..||| | |||.. | .         |.. .|.||.|||||||..| 
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

TPFVSSTIQDLFEEITNENLHISFPE--------------EDEIPDDAQDLVRQ----LMCFDPMYRLGSTAREGVSGVKSHPFF
.||        ...| . .. ...||               ........|| ..    ... ||  |..     | . .. ||.|
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT-----GWEQILNHPWF

Kinase AqueK009.AA Pkinase 511-787 30 2.6e-79 274.57 Pfam 1-293 (293) Show / Hide
Range on Protein: 511-787
Range on HMM: 1-293/293
Sequence Identity: 30% (95 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVF-NERDILTFSENPFVVGLWCTFQTRQHLYMVMEYVEGG----DVAALLK--GV
. ....|  |..| ||. .|| |. ..|.|...|..  ..|... .  .|  |.     |..| |...|....|.||||||.|||    | .....    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GYL--TLELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHI----KLTDFGLSKIGLTNYAAHVIEDAWAKDYQFVDQEVYGTPDYIAPEVIL-
| .  . . . .|. ... .|||.||.|||||||||.|.|| ..|||    |..||||.|                  ..  .  . |||.|.|||||. 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------------Y-NNS-MTTFC-GTPWYMAPEVIRG

GMPYGFPVDWWSMGVILYEMMMGVTPFVSS------TIQDLFEEITNENLHISFPEEDEIP-----------------DDAQDLVRQLMCFDPMYRLGST
| .|| .||.||.|.|||||. | .|| ..      . . ....|    || ..|....|.                 ....|... . |.||  |..  
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT--

AREGVSGVKSHPFF
       .. ||.|
----AEQILQHPWF

Kinase AqueK009.AA NDR 511-663 48 4.4e-77 237.13 In-house 1-158 (350) Show / Hide
Range on Protein: 511-663
Range on HMM: 1-158/350
Sequence Identity: 48% (76 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSE--NPFVVGLWCTFQTRQHLYMVMEYVEGGDVAA---LLKGVGY
|..||||. ||.| |.|||.| |.  .|||...|. |..| || .| .||||.. .   ||.|| | ..||  |.|| ||||. |||      ||.  ..
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LTLELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTNY
.| ..|  | .|.|.|.|..|. |.||||.||||.|| . ||||||||||.. |.. .
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRR

Kinase AqueK009.AA Akt 511-662 41 1.6e-57 182.45 In-house 1-155 (264) Show / Hide
Range on Protein: 511-662
Range on HMM: 1-155/264
Sequence Identity: 41% (64 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRF-AMKKVNKKRMIMKKQVQSVFNERDILTFSENPFVVGLWCTFQTRQHLYMVMEYVEGGDVAALLKGVGYLTLE
||..|..  |..| |.||. |.|   . |||   |.. |.|.||. .. || ||    .||.|.|   ||| ..||.||.|. ||.   .|.  .. . .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

LATMYFSETVLALEYIHSHGIIHRD-LKPDNLLITSEGHIKLTDFGLSKIG-LTN
 |  | .| .||.|. ||..|| || ||| |.|. ..|||.||||||.| . ...
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKD

Kinase AqueK009.AA PKA 511-657 45 5.2e-56 192.4 In-house 1-149 (263) Show / Hide
Range on Protein: 511-657
Range on HMM: 1-149/263
Sequence Identity: 45% (68 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSENPFVVG-LWCTFQTRQHLYMVMEYVEGGDVAALLKGVGYLTLE
|. |. . .| .| |.|.|||..   .|||  .| . .  |||. | ||. ||.  ..||.|  .. |||....||||||||.||..   |  .| ..  
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

LATMYFS-ETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSK
 |  |   . ||||||.||. ||.||||| |.|| ..||||.|||| .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAK

Kinase AqueK009.AA NDR 685-787 45 2.1e-42 128.18 In-house 243-350 (350) Show / Hide
Range on Protein: 685-787
Range on HMM: 243-350/350
Sequence Identity: 45% (50 aa)

GTPDYIAPEVILG-MPYGFPVDWWSMGVILYEMMMGVTPFVSSTIQDLFEEITN--ENL---HISFPEEDEIPDDAQDLVRQLMCFDPMYRLGSTAREGV
|||||.||||...   |.. .|||| |.|.||| .|..||.|.|.|. .. | |  . .    ..||.| .. ..|.|| |.|.| ||. ||||   .||
GTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHG-KGV

SGVKSHPFF
  .||||||
DEIKSHPFF

Kinase AqueK009.AA Akt 685-787 37 1.7e-32 101.15 In-house 164-264 (264) Show / Hide
Range on Protein: 685-787
Range on HMM: 164-264/264
Sequence Identity: 37% (39 aa)

GTPDYIAPEVILGMPYGFPVDWWS-MGVILYEMMMGVTPFVSSTIQDLFEEITNENLHISFPEEDEIPDDAQDLVRQLMCFDPMYRLGSTAREGVSGVKS
||| |.|||...|  .. .||||.  |...|||| |  || .  .. .|. | |...   ||. | | ....||...|   ||  |||..  ...  .|.
GTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPV--KFPDKDWISPECKDLISGLLNKDPKKRLGGGP-NDAQEIKR

HPFF
||.|
HPWF

Kinase AqueK009.AA PKA 685-787 35 2.7e-28 100.31 In-house 160-263 (263) Show / Hide
Range on Protein: 685-787
Range on HMM: 160-263/263
Sequence Identity: 35% (39 aa)

GTPDYIAPEVILGM-PYGFPVDWWSMGVILYEMMMGVTPFVSS--TIQDLFEEITNENLHISFPEEDEIPDDA---QDLVRQLMCFDPMYRLGSTAREGV
|||.|.|||.|..  ..| .||||. |.. |||. |..||  .  .  ...| |   |  | ||...    ||    ||...|.  |. .|.| . ..||
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKIC--NGKIKFPRHFD--SDANYFKDLIKKLLQVDLTKRYG-NMKNGV

SGVKSHPFF
  .| |..|
NDIKNHKWF

Kinase AqueK009.AA TyrKc 511-781 21 1e-12 -17.13 SMART 1-280 (280) Show / Hide
Range on Protein: 511-781
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFS--ENPFVVGL--WCTFQTR-----QHLYMVMEYVEGGDVAALLK
   .|.. .||.| ||. . |   .  | |....        ..   .|  |..    ..| .| |   || | |     . |..||||...||    |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

GVGY-LTLELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTN-YAAHVIEDAWAKDYQFVDQEVYGT-----PD------
  .  |...    .        ||.||...|||||   | |.......| .|||||. .     .              . ...| .      .      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-------------ESKDYYRKKEHKGGKTMLPIR

YIAPEVILGMPYGFPVDWWSMGVILYEMM-MGVTPFVS-----STIQDLFEEITNENLHISFPEEDE------IPDDAQDLVRQLMCFDPMYRLGSTARE
  |||.|    . .  | || || ..|..  | .|         . |...| . . .     |..|.       ||.  ..   ..| .       | .|
WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYR-MPQPPNDYPMSFVCCPDEMYQIM--KQCWHEDPEDRPTFSE

GVSGV
 ..  
IHECF

Kinase AqueK009.AA Pkinase_Tyr 581-657 31 2.8e-09 32.04 Pfam 77-159 (270) Show / Hide
Range on Protein: 581-657
Range on HMM: 77-159/270
Sequence Identity: 31% (26 aa)

RQH--LYMVMEYVEGGDVAALLKG----VGYLTLELATMYFSETVLALEYIHSHGIIHRDLKPDNLLITSEGHIKLTDFGLSK
...  .|.||||...||    |.      . ||..    .  .   ..|| .|...|||||   | |.|.....| .||||..
GEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR

Kinase AqueK009.AA S_TK_X 788-848 19 1e-07 32.86 SMART 1-79 (79) Show / Hide
Range on Protein: 788-848
Range on HMM: 1-79/79
Sequence Identity: 19% (17 aa)

SEIDWNLLLR----TKAEFIPQLR----GDDDTSYFD---TRENRYPQNEFASDEEPDGDT------DQP----------FDNFSSTA
..|||. |..    ... |.|...    .. |||.||   |.|            . . |.      .|.          | .|.  .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM---------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase AqueK009.AA Pkinase_C 805-850 23 0.000505 17.5 Pfam 1-46 (46) Show / Hide
Range on Protein: 805-850
Range on HMM: 1-46/46
Sequence Identity: 23% (11 aa)

QLRGDDDTSYFDTRENRYPQNE-FASDEEPDGDTDQPFDNFSSTAPR
|.....|||.||. . . | .. . ...      . || .|. ..| 
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD

PDZ AqueK009.AA PDZ 1034-1115 20 8.9e-09 36.41 SMART 1-80 (80) Show / Hide
Range on Protein: 1034-1115
Range on HMM: 1-80/80
Sequence Identity: 20% (19 aa)

KGYGMTLKPIRVYIGDSNNYRIHHIVQSVDKDGPAYKAG------LRPNMLVTHING-EAVTGLQHVQVVSLMFKNSK----KDASAKAKDSK
.|.| ...              .... || ..|||.|||      |||.  .. .|| . |... | |.| .. . ..    .  . . .  .
GGLGFSIVG-------------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG