Gene AqueK084 (A.queenslandica)

AqueK084

Species: A.queenslandica
Alias: AqueK084
External Links:
Annotation:

Classification

Group: CAMK
Family: SgK495

Sequence

Name Sequence Type Origin Length Description Download
AqueK084.AA Protein None 2209 None Fasta, JSON
AqueK084.kin_dom Protein Kinase Domain None 169 None Fasta, JSON

Protein domain

Protein domains of AqueK084.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK084.AA SgK495 1750-1920 57 1.1e-95 296.46 In-house 1-171 (171) Show / Hide 
Range on Protein: 1750-1920
Range on HMM: 1-171/171
Sequence Identity: 57% (98 aa)

NLQQYIIKERRLPEREALQLFYQLVCIVKEIHKKKIVHRDLKLANVVINKRTQQVFLTNFALGKHLVHEDDLLSDQRGSLAYVSPDVISGEPYYGMPSDM
||| ..|.|.|| |||.  .|.  | ||  .|.| |||||||| |.|.|..|.|. .||| |||||| | ||| ||||| ||.||||.|| || | ||||
NLQHHVIHEKRLSERETVYIFHDVVRIVEALHQKNIVHRDLKLGNMVLNCHTHQITITNFCLGKHLVSEHDLLKDQRGSPAYISPDVLSGRPYRGKPSDM

WSLGVLLYTMISGQFPYYDDIPQELFRKIKSGKFVLPRDLVISIETQYLLKELMELDQRKRLTALAAAETT
| ||| |.||. ||||.|| ||||||||||   . .|.|  .|  |  |...|. || ..||||    |. 
WALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPQDGRVSENTVCLIRKLLVLDPQQRLTATQVIEAV
Kinase AqueK084.AA CAMK 1751-1913 22 1.2e-55 177.39 In-house 151-416 (425) Show / Hide 
Range on Protein: 1751-1913
Range on HMM: 151-416/425
Sequence Identity: 22% (60 aa)

LQQYIIKE---------------RRLPEREALQLFYQLVCIVKEIHKKKIVHRDLKLANVVINKRT----------------QQVFLTNFALGKHLVH--
| .||..                .|..|||| ..| |... |. .|...|||||||. |. ....                  .. .. | . ... .  
LFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGE

---------------------EDDLLSDQRGSLAYVS-PDVISG-------------EPYYGMPSDMWSLGVLLYTMISGQFPYYDD-------------
                     |....... |...|.. | |..|             .|||| ..||||.||.||.| .| .|.|.|             
NNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGM

IPQELFRKIKSGKF--VLPR------------DLVISIE--------TQYLLKELMELDQRKRLTA
 ..|||.||..||.    |             .  || |         . |.. ... |  ||.|.
NDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTI
Kinase AqueK084.AA CAMKL 1751-1913 29 1.6e-42 133.42 In-house 110-288 (297) Show / Hide 
Range on Protein: 1751-1913
Range on HMM: 110-288/297
Sequence Identity: 29% (53 aa)

LQQYIIKE----RRLPEREALQLFYQLVCIVKEIHKKKIVHRDLKLANVVINKRTQ-QVFLTNFALGKHLV-H---EDDLLSDQRGSLAYVSPDVISG--
|..||.|.    .|.||.|| ..| |.|. |. .|...|||||.|. |. . ..   .. .. | .. .   .   ....|. . ||..| .| ...|  
LFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNN

EPYYGMPSDMWSLGVLLYTMISGQFPYYDDIPQ-------ELFRKIKSGKFVLPRDLVISIETQYLLKELMELDQRKRLTA
.||.| . |.||.||.||.|. |..|  ||  .       .|..||..| .  |  . .| . . |.. ... .  || |.
KPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTI
Kinase AqueK084.AA MARK 1750-1913 33 2.6e-37 119.61 In-house 88-253 (262) Show / Hide 
Range on Protein: 1750-1913
Range on HMM: 88-253/262
Sequence Identity: 33% (56 aa)

NLQQYIIKE--RRLPEREALQLFYQLVCIVKEIHKKKIVHRDLKLANVVINKRT-QQVFLTNFALGKHLVHEDDLLSDQRGSLAYVSPDVISGEPYYGMP
.| .||..   .||.|.|| ..| |.|. |.  |.| |||||.|. |. | ... ... .. | .. . . .. .|.   |...| .| .....||.| .
ELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSIC-IPPGQKLNTFCGTPPYMAPEIFLKKPYDGPK

SDMWSLGVLLYTMISGQFPYYDDI--PQELFRKIKSGKFVLPRDLVISIETQYLLKELMELDQRKRLTA
 |.|||||.||.|..|.||. .|     ||..|| .||.  |    .| | . |.. |. ..  .| |.
VDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTI
Kinase AqueK084.AA GIN4 1745-1912 32 6e-36 112.01 In-house 115-283 (293) Show / Hide 
Range on Protein: 1745-1912
Range on HMM: 115-283/293
Sequence Identity: 32% (55 aa)

YKDFVNLQQYIIKERRLPEREALQLFYQLVCIVKEIHKKKIVHRDLKLANVVINKRTQQVFLTNFALGKHLVHEDDLLSDQRGSLAYVSPDVISGEPYYG
| .   | .|.... .||||||.. | |..  |   |   |.|||||  |... .. ... .  | .   |  . .||    ||  | .|....| || |
YAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMA-ALETDNKLLETSCGSPHYAAPEIVMGIPYHG

MPSDMWSLGVLLYTMISGQFPYYDD--IPQELFRKIKSGKFVLPRDLVISIETQYLLKELMELDQRKRLT
 .||.|| ||.|. .. |. |. ..    ..|  |...||. .| |  || | | |.. .. .| .||..
FASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEKRIK
Kinase AqueK084.AA AMPK 1754-1912 37 1.3e-34 100.27 In-house 90-244 (254) Show / Hide 
Range on Protein: 1754-1912
Range on HMM: 90-244/254
Sequence Identity: 37% (59 aa)

YIIKERRLPEREALQLFYQLVCIVKEIHKKKIVHRDLKLANVVINKRTQQVFLTNFALGKHLVHEDDLLSDQRGSLAYVSPDVISGEPYYGMPSDMWSLG
||.| .||.||||  .| | .  |  .|. .|||||||. |. ..   ... .  | | . .  . ..|.   ||  | .| .||| .| |   | || |
YIVKHGRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLD-HNKNIKIVDFGLSN-MMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCG

VLLYTMISGQFPYYDDIPQELFRKIKSGKFVLPRDLVISIETQYLLKELMELDQRKRLT
| || |. |  |  |.   .|..|||.|.. .|..|  | | ..|.|.. . |  ||.|
VILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFL--SPEAKDLIKHMLQVDPMKRIT
Kinase AqueK084.AA Ciliate-E2-Unclassified 1750-1913 20 1.9e-34 116.92 In-house 107-343 (352) Show / Hide 
Range on Protein: 1750-1913
Range on HMM: 107-343/352
Sequence Identity: 20% (48 aa)

NLQQYIIKE-----------------RRLPEREAL-----QLFYQLVCIVKEIHKKK-IVHRDLKLANVVINKRTQ--QVFLTNFAL-------------
.|.||| |                  ....|..|.     ..|.|...  . .|.|. |.|||.|. |.....  .  .. .. | .             
DLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTN

--GKHLVHEDDLLSDQRGSLAYV----SPDVISGEPYYGM---PSDMWSLGVLLYTMISGQFPYYD-DIPQ---------------ELFRKIKSGKFVLP
   |  .  ....... |.. |     .| |. |. |...    .|.|||||.|| |. |..|.|| .  |               .|...|| ...  |
QQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFP

RDL------VISIETQYLLK----ELMELDQRKRLTA
          .| | . ...     ... .. ||.|.
KFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITF
Kinase AqueK084.AA CAMK-Unique 1751-1913 20 3.5e-34 110.1 In-house 122-354 (363) Show / Hide 
Range on Protein: 1751-1913
Range on HMM: 122-354/363
Sequence Identity: 20% (49 aa)

LQQYIIK--------------------ERRLPE--REALQLFYQLVCIVKEIHKKKIVHRDLKLANVVINKR---------------TQQVFLTNFALGK
|...|.|                    .... |  ....... .|.  |.  |...|||||||| |......                  ..|..| | .
LFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCC

HLVHEDDL--LSDQRGSLAYVSP--------------DVISGEPYYGMPS----DMWSLGVLLYTMISGQFPYYDDIPQ--------ELFRKIKSGKF-V
|. |      ..   |.. |..|               || . . |. ..    | |||||..|.|..|  | . .           |.|..|..|..  
HYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQC-YDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCN

LPRDL--V---ISIETQYLLKELMELDQRKRLTA
....   .   || |   ..| .|..|. .|..|
FDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSA
Kinase AqueK084.AA Trbl 1754-1913 37 2.5e-33 102.36 In-house 88-247 (256) Show / Hide 
Range on Protein: 1754-1913
Range on HMM: 88-247/256
Sequence Identity: 37% (61 aa)

YIIKERRLPEREALQLFYQLVCIVKEIHKKKIVHRDLKLANVVINKRT-QQVFLTNFALGKHLVHEDDLLSDQRGSLAYVSPDVISGEP-YYGMPSDMWS
|. . .||.|.||  ||.|..  |   |.  || |||||   |  ..   .. | .   .  .  ||| |.|  |  ||||| . . .. | | . ||||
YVRHRKRLCEEEAARLFHQMCQAVAHCHQHGIVLRDLKLRRFVFKDEERTKLQLESLEDSCIMTGEDDSLWDKHGCPAYVSPEILCTQGSYSGKAADMWS

LGVLLYTMISGQFPYYDDIPQELFRKIKSGKFVLPRDLVISIETQYLLKELMELDQRKRLTA
||| ||||  |..|..|  |  || ||  |.| .|  . .| .   |.  |.  .   |.||
LGVMLYTMLVGRYPFHDSEPCNLFTKIRRGQFCIP--EHLSPKARCLIRCLLRREPSERMTA
S_TKc AqueK084.AA S_TKc 1664-1929 22 1.5e-32 115.38 SMART 16-231 (231) Show / Hide 
Range on Protein: 1664-1929
Range on HMM: 16-231/231
Sequence Identity: 22% (62 aa)

YIAKKTDGDEFVTMKILSLSPGGNSPEDSQGKSLIHNEHSILSLLQDQIGIIQQHGLYREGNNIILVLDCLYQHEYGSTDQYKDF--VNLQQYIIKERR-
| ..... .. | .||..                | .| .||.   .   |.. .. ... ... .|....            |    .| .|| | .| 
YKCRHKKTGRIVAIKIIK--------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYC------------DGDLGDLFDYIKKRGRH

-----LPEREALQLFYQLVCIVKEIHKKKIVHRDLKLANVVINKRTQQVFLTNFALGKHLVHEDDLLSDQRGSLAYVSPDVISGEPYYGM-PSDMWSLGV
     .|| .|  ..||..| .. .|...|.||||| .|. ...   .. .. | | ..|       . . |.. |..| |.     ||  ..|.||.|.
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGC

LLYTMISGQFPYYDDIPQELFRKIKSGKFVLPRDLVISIETQYLLKELMELDQRKRLTALAAAETTQSILSRISF
.|| |..|. |..   .|..|.||.            | |   ... ... | .||.||  | .  . | .   |
ILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK084.AA Pkinase 1751-1916 23 1.9e-32 115.83 Pfam 91-287 (293) Show / Hide 
Range on Protein: 1751-1916
Range on HMM: 91-287/293
Sequence Identity: 23% (47 aa)

LQQYII--KERRL--PEREALQLFYQLVCIVKEIHKKKIVHRDLKLANVVINKRTQQV----FLTNFALGKHL-VHEDDLLSDQRGSLAYVSPDVISGEP
|  ||   .....  .|.|.   .||... .. .|...|.|||||..|. |. .. ..     .. | | |..    .  ...  |.. |..| || | .
LFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQ

YYGMPSDMWSLGVLLYTMISGQFPYYDD------IPQELFRKIKSGKFVLPRDLVIS-------------------IETQYLLKELMELDQRKRLTALAA
||| ..||||.|..|| |..|..|....       .......|.....  ...  .|                    | . ..| . ..|  ||.||  .
YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI
Kinase AqueK084.AA RSK 1757-1913 25 1.4e-30 107.95 In-house 94-264 (278) Show / Hide 
Range on Protein: 1757-1913
Range on HMM: 94-264/278
Sequence Identity: 25% (44 aa)

KERR---LPEREALQLFYQLVCIVKEIHKKKIVHRDLKLANVVINKRTQQ---VFLTNFALGKHLVHE-DDLLSDQRGSLAYVSPDVIS---GEPYYGMP
||..   . |.|| . ....|. |. .|...|.|||||. |.. . .. .   . || | . | .. .   ..   .....|. | ..    ..  ..  
KEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKA

SDMWSLGVLLYTMISGQFPYYD---DIPQELFRKIKSGK--FVLPRDLVISIETQYLLKELMELDQRKRLTA
 | ||||||.|.| .|. |..    . ..|....|..||  . .|..  .| | . |.. ... |  |||..
CDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGC
TyrKc AqueK084.AA TyrKc 1633-1924 16 7.7e-09 -79.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 1633-1924
Range on HMM: 1-280/280
Sequence Identity: 16% (55 aa)

LHLTNGLQSGEY---YIGPRLNTVSPSPVKSVSEYIAKKTDGDEFVTMKILSLSPGGNSPEDSQGKSLIHNEHSILSLL-QDQIGIIQQHGLYREG----
..|   | .|..   | |                         . |  | |  .           .  ...| .|.. |  .   |.. .|  ...    
ITLGKKLGEGAFGEVYKGTWK----------------------IQVAVKMLKEDA----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNF

---NNIILVLDCLYQHEYGSTDQYKDFVNLQQYIIKERR-LPEREALQLFYQLVCIVKEIHKKKIVHRDLKLANVVINKRTQQVFLTNFALGKHLVHE--
     . .|.             | .  .|..|. | |. |. .. |.  .|  |    .|.|...||||   |. ....  .|  . | | . . ..  
MYIEPLMIVM------------EYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQ

-----DDLLS----DQR--GSLAYVSPDVISGEPYYGMPSDMWSLGVLLYTMIS-GQFPYYD-----DIPQELFRKIKSGKFVLPRDLV-------ISIE
     |   .    . .    .   .| .|  .  .   || || ||... . . || ||..       .||.....|.|.   . . .        . |
QGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDE

TQYLLKELMELDQRKRLTALAAAETTQSIL
   . |.  . |  .| |  .      ...
MYQIMKQCWHEDPEDRPTFSEI----HECF