Gene AqueK091 (A.queenslandica)

AqueK091

Species: A.queenslandica
Alias: AqueK091
External Links:
Annotation:

Classification

Group: CK1
Family: TTBK

Sequence

Name Sequence Type Origin Length Description Download
AqueK091.AA Protein None 439 None Fasta, JSON
AqueK091.kin_dom Protein Kinase Domain None 206 None Fasta, JSON

Protein domain

Protein domains of AqueK091.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK091.AA TTBK 25-279 54 2.1e-142 479.37 In-house 1-257 (257) Show / Hide 
Range on Protein: 25-279
Range on HMM: 1-257/257
Sequence Identity: 54% (139 aa)

WKVLGKIGGGGFGEIYKVKDLSNN-EDFALKAESLSSNRQVLRMEALVLKRLQGIPQVCEFIGCGRTEKANFLVMTLLGPNLSELRKKQADQKFSISTVL
|||. |||||||||||  ||. |. |  |.| ||    .|||.||  |||.||| . || |||||| .| |..||.|.| ||..|| || ...||.|| |
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL

RLGVQIIKVVQSMHNCGFLHRDLKPSNFAMG-AGENAKTCFLLDFGLSRQYIMPTGELKPPRGTTGFRGTIRYASLNAHKGCDLGRQDDLWSVFYMLVEL
||||||.. ..| |. |||||| |||||||| . .. . |..||||| |||.  .||  |||  .|||||.|||| |||.  ..||.|||||.|||||| 
RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEF

ANGSLPWKTLREKEDVGKAKLHYNHHKLITTLPHEFNAYLEYLQQLTYYDKPNYAYL
..| |||  .. |..||. |  |.|  |.  .||||  ... .. |.| |.|.|. .
VQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase AqueK091.AA CK1 25-279 33 1.2e-120 407.11 In-house 1-339 (339) Show / Hide 
Range on Protein: 25-279
Range on HMM: 1-339/339
Sequence Identity: 33% (113 aa)

WKVLGKIGGGGFG-EIYKV-----KDLSNN-----EDFALKAESLSSNRQ-VLRMEALVLKRL---------------------QGIPQVCEFIGCGRTE
|||  |||.|||| .||||     ||..||     |..|.|.|. .|. |  ..||. .....                     .|.| .| .. .|...
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

KAN-FLVMTLLGPNLSELRK--KQADQKFSISTVLRLGVQIIKVVQSMHNCGFLHRDLKPSNFAMGA-------------GENAKTCFLLDFGLSR-QYI
. . ..|||||||||..|||  .. ..||| .|.|....|...... ||.|||.|||.||.||.||.             ...... ...|||..| .|.
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

MP------------TGELKPPRG---TTGFRG-TIRYASLNAHKGCDLGRQDDLWSVFYMLVELANGS--LPWKTLREKED-----VGKAKLHYNHHKLI
..            |....|||    ..|||| |.||.|.|.|.|...|| |||||.||||.|.  |.  |||. .....      |.|.|  . . |. 
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM

TT------------LPHEFNAYLEYLQQLTYYDKPNYAYL
 |            .| ||  ...|. .|.|||.|.|...
STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase AqueK091.AA TTBKL 25-283 35 1.9e-116 393.15 In-house 1-288 (288) Show / Hide 
Range on Protein: 25-283
Range on HMM: 1-288/288
Sequence Identity: 35% (104 aa)

WKVLGKIGGGGFGEIYKVKDLSN-NEDFALKAESLS-SN-RQVLRMEALVLKRLQ--GIPQVCEFIGCGRTEKANFLVMTLLGPNLSELRKKQADQK-FS
|.. ..||.||||..|.|.|... .. .|.|.|. . ..  ... ||. ||..||  | | .......|.... ||.||||.||||. |||.   .| ||
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

ISTVLRLGVQIIKVVQSMHNCGFLHRDLKPSNFAMGAGEN----AKTCFLLDFGLSRQYIMPTGEL-----------KPPRG---TTGFRGTIRYASLNA
 .|..|.|.|...... || |||.|||.||.|...|. ..    ... .|.|||..|||... ||.           ..||    ...||||.||.|.|.
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HKGCDLGRQDDLWSVFYMLVELANGSLPWKTLREKEDVGKAKLHYNHHKLITT------LPHEFNAYLEYLQQLTYYDKPNYAYLIELF
| ....|| |||||..||..||. | |||. . .|......|.. .. .|         .| ||    ..| .|.||| |.| ...|.|
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase AqueK091.AA Worm6 25-279 38 1.1e-108 367.34 In-house 1-279 (279) Show / Hide 
Range on Protein: 25-279
Range on HMM: 1-279/279
Sequence Identity: 38% (108 aa)

WKVLGKIGGGGFGEIYKVKDLSNNE--DFALKAES--LSSNRQVLRMEALVLKRLQGIP--QVCEFIGCGRTEK--ANFLVMTLLGPNLSELRKKQADQK
|||. ||| |||| .|||.| |...   ||.|.|.   .. ||.|.||. |||..  ..  ..|... .|....   |..||||.|.||..||| ..|.|
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FSISTVLRLGVQIIKVVQSMHNCGFLHRDLKPSNFAMGA-----GENAKTCFLLDFGLSR--QYIMPTGELKPPR-GTTGFRGTIRYASLNAHKGCDLGR
|| .| |... | .. .. .|||||.|||.||.||. |       .. .| ..||||..|  .|.   .||..||  . ||||| |||.|..|||....|
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCR

QDDLWSVFYMLVELANGSLPWKTLREKEDVG-KAKLHYNHHK------LITTLPH-EFNAYLEYLQQLTYYDKPNYAYL
.||. | |||.||.  | |||. .... .|.  .|  ... .      .  . |. |||. ..|. |. |.|.|.|...
KDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase AqueK091.AA CK1 25-277 35 1.2e-69 237.64 In-house 1-271 (271) Show / Hide 
Range on Protein: 25-277
Range on HMM: 1-271/271
Sequence Identity: 35% (98 aa)

WKVLGKIGGGGFGEIYKVKDLSNNEDF---ALKAESLSSNRQVLRMEALVLKRLQG---------IPQVCEFIGC--GRTEKANFLVMTLLGPNLSELRK
 .|  ||| | ||.||..... .|. .   | | |.  |  . |  || ..|.|||         ||..  .  .  |   . |..||.||||.| .| .
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQG---DYNIMVMDLLGPSLEDL-F

KQADQKFSISTVLRLGVQIIKVVQSMHNCGFLHRDLKPSNFAMGA-GENAKTCFLLDFGLSRQYI-MPTGELKPPRGTTGFRGTIRYASLNAHKGCDLGR
.  ..|||. ||| .. |.|. .. .||..|.|||.|| || ||  | ....... ||||. .|. . |..  | |   .. || ||||.|.| |   .|
NFCNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSR

QDDLWSVFYMLVELANGSLPW-----KTLREK-EDVGKAKLHYNHHKLITT-LPHEFNAYLEYLQQLTYYDKPNYA
 ||. |. |.|. .. |||||     .| ..| |  .  |. ...  |    .| ||. ||.|  || ...||.|.
RDDMESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase AqueK091.AA CK1-Unclassified 25-229 41 6.4e-69 202.54 In-house 1-216 (244) Show / Hide 
Range on Protein: 25-229
Range on HMM: 1-216/244
Sequence Identity: 41% (89 aa)

WKVLGKIGGGGFGEIYKVKDLSNNEDFALKAESLSSNRQVLRMEALVLKRLQGIP-------QVCEFIGCGRTEK--ANFLVMTLLGPNLSELRKKQADQ
 .|. ||| | ||||||.... .|| .|.| |.  |    |  || ....||.          .   . ||. |.   |..||.||||.| .| ..   .
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDL-FNMCNR

KFSISTVLRLGVQIIKVVQSMHNCGFLHRDLKPSNFAMG-AGENAKTCFLLDFGLSRQYIMP--TGELKPPRGTTGFRGTIRYASLNAHKGCDLGRQDDL
|||. ||| .. |.|. .. .||..|.|||.|| || ||  | |...... |||||  || .  ||.  | |   .. || ||||.|||.|   .| |||
KFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDL

WSVFYMLVELANGSLPW
 |. | |. .. |||||
ESLGYVLIYFLKGSLPW
Kinase AqueK091.AA CK1-D 25-279 37 3.5e-59 202.92 In-house 1-261 (261) Show / Hide 
Range on Protein: 25-279
Range on HMM: 1-261/261
Sequence Identity: 37% (97 aa)

WKVLGKIGGGGFGEIYKVKDLSNNEDFALKAESLSSNRQVLRMEALVLKRLQGIPQVCEFIGCGRTEKANFLVMTLLGPNLSELRKKQADQKFSISTVLR
...  |||.| ||.||  .....||. |.| |.. .    | .|. . | .||   . |   ||.    | .|| |||| | .|     . |||. ||| 
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLF-NYCHRKFSLKTVLM

LGVQIIKVVQSMHNCGFLHRDLKPSNFAMGAGENAKTCFLLDFGLSRQYIMPT-GELKPPRGTTGFRGTIRYASLNAHKGCDLGRQDDLWSVFYMLVELA
|. |.|. .. .|   |.|||.|| || || |   .. ...||||...|  .   .  | |      || ||||.| |.| .  | ||| |. |.|.  .
LADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFN

NGSLPWKTL-----REK-EDVGKAKLHYNHHKLITTLPHEFNAYLEYLQQLTYYDKPNYAYL
 |||||. |     |.| | .   |.. . ..|   .|.||  |..| ..| . |||.|.||
RGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase AqueK091.AA CK1-A 25-279 34 2e-52 180.49 In-house 1-261 (261) Show / Hide 
Range on Protein: 25-279
Range on HMM: 1-261/261
Sequence Identity: 34% (91 aa)

WKVLGKIGGGGFGEIYKVKDLSNNEDFALKAESLSSNRQVLRMEALVLKRLQGIPQVCEFIGCGRTEKANFLVMTLLGPNLSELRKKQADQKFSISTVLR
.... ||| | ||.||    . | |. |.| ||       |  || | . ||| . . .    |.    | .|| |||| | .|     . .|.. ||| 
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLF-NFCKRRFTMKTVLM

LGVQIIKVVQSMHNCGFLHRDLKPSNFAMGAGENAKTCFLLDFGLSRQYIMPTGELK-PPRGTTGFRGTIRYASLNAHKGCDLGRQDDLWSVFYMLVELA
|  |.|  .  .|. .|.|||.|| || || |      ||.||||...|  .  .   | |      ||.||||.||| | .  | ||. |. |...   
LADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFN

NGSLPWKTLREK------EDVGKAKLHYNHHKLITTLPHEFNAYLEYLQQLTYYDKPNYAYL
 |.|||. .. .      | .   |.     .|    | ||  |..| ..| . ..|.| ||
RGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase AqueK091.AA Dual 25-283 26 8.9e-43 141.6 In-house 1-282 (282) Show / Hide 
Range on Protein: 25-283
Range on HMM: 1-282/282
Sequence Identity: 26% (75 aa)

WKVLGKIGGGGFGEIYKVKDLSN----NEDFALKAESLSSNRQVLR--MEALVLKRLQG---------IPQVCEFIGCGR--TEKANFLVMTLLGPNLSE
|||   .| |||...|.| . |     |. ..|| ||    .  ||   |. | .   .            . ||.  |   . | ...|| . || | |
WKVVNLLGSGGFRDVYHVHRFSQVNPKNKCYILKTESEEGEKMMLRLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSLQE

LRKKQADQKFSISTVLRLGVQIIKVVQSMHNCGFLHRDLKPSNFAMGAGENAKTCFLLDFGLSRQYIM-PTGELKPPRGTTGFRGTIRYASLNAHKGCDL
 |.|     .| ..    . | .. .|  |. |.|||. ||.||. | |.   | ...||.. | ||   ... ...| .  . |. |||.    .  | 
IRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKDQ

GRQDDLWSVFYMLVELA-NGS-LPWKTLREKEDVGKAKLHYNHHKLITT---LPHEFNAYLEYLQQLTYYDKPNYAYLIELF
|| ||| .  ||.  |  ... ..|. ...   . |.|     |..  .    | ..   . |   . |   | |.|..   
GRKDDLECWIYMVFDLMDPEHGMSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL
Kinase AqueK091.AA CK1-Unique 25-230 26 8.8e-41 139.1 In-house 1-233 (337) Show / Hide 
Range on Protein: 25-230
Range on HMM: 1-233/337
Sequence Identity: 26% (62 aa)

WKVLGKIGGGGFGEIYKVKDLSNN------EDFALKAESLSSNRQ--VLRMEALVLKRLQGIP-------QVCEFIGCGRTEKANFLVMTLLGPNLSELR
|.|  .||.||.|  ..| .. |         .. | |  .  .    |  | .|.| .            .|| .  . .  . ..|||..||.. |..
WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEECC

KKQADQKFSIS------TVLRLGVQIIKVVQSMHNCGFLHRDLKPSNFAMGAGE--NAKTCFLLDFGLSRQ--YIMPTGELKPPRGTTGFRGTIRYASLN
 . .  .|  .      .....| |.  |.  ||  ||.||..|| |.  .|      .. . ||.| .|    . . .....|| .| |||. .|..  
MMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKDYCPCS

AHKGCDLGRQDDLWSVFYMLVELANGS--LPWK
 |.  ..|| ||. | ||||. |  .   | ||
CHQCREHGRRDDMESWFYMLYHLVHNTRGLSWK
Kinase AqueK091.AA Pkinase 25-230 22 6.6e-24 85.62 Pfam 1-213 (293) Show / Hide 
Range on Protein: 25-230
Range on HMM: 1-213/293
Sequence Identity: 22% (51 aa)

WKVLGKIGGGGFGEIYKVKDLSNNEDFALKAESLSSNRQVLRM------EALVLKRLQGIPQVCEFIGCGRTEKANFLVMTLLGP-----NLS----ELR
.....||| |.||. || .. .... .|.|  ......   ..      |. ..||| . | ....... ....   .|| ...       |.       
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

KKQADQKF--SISTVLRLGVQIIKVVQSMHNCGFLHRDLKPSNFAMGAGENAKTCF-LLDFGLSRQYIMPTGELKPPRGTTGFRGTIRYASLNAHK-GCD
  ... .|  |  .. .   ||.. .. .|..|..||||||.|. .    . ..|. . ||||..|.      . . . .|.| ||..|..   .. | .
--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGGQY

LGRQDDLWSVFYMLVELANGSLPWK
 |.  | ||.  .| |...| .|..
YGPKVDMWSCGCILYEMLCGRPPFP
Kinase AqueK091.AA S_TKc 25-305 20 7.9e-19 69.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-305
Range on HMM: 1-231/231
Sequence Identity: 20% (60 aa)

WKVLGKIGGGGFGEIYKVKDLSNNEDFALKAESLSSNRQVLRMEALVLKRLQGIPQVCEFIGCGRTEKANFLVMTLLGP---NLSELRKKQADQK----F
...| ||| |.||. ||... . .. .|.|  .     . .| |  .||.  . | .. .... .. .  ..|| ...    .| .. ||.  ..    |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

SISTVLRLGVQIIKVVQSMHNCGFLHRDLKPSNFAMGAGENAKTCFLLDFGLSRQYIMPTGELKPPRGTTGFRGTIRYASLNAHKGCDLGR-QDDLWSVF
.  .. ..  ||.. .. .|. |..||||||.|  .       .  . ||||.||.             | | ||  | .         |.   | ||. 
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

YMLVELANGSLPWKTLREKEDVGKAKLHYNHHKLITTLPHEFNAYLEYLQQLTYYDKPNYAYLIELFEQAQRNLRISECHPLDWE-----QPAV
 .| |.. |  |.    . . . |  .                              |    .|.   |   . |..    |  |      | .
CILYEMLCGYPPFP---QMQMMFKKIG-----------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK091.AA TyrKc 25-283 16 3e-06 -121.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-283
Range on HMM: 1-280/280
Sequence Identity: 16% (51 aa)

WKVLGKIGGGGFGEIYKVKDLSNNEDFALKAESLSSNRQVLRMEALVLKRL-QGIPQVCEFIGCGRTEK------ANFLVMTLLGPN---LSELRKKQAD
 . . |.| | |||.|| .     .. | |    .. |. .. || ....|    | .  ..|. ....         .. . . |.   .. |||.. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

QKFSISTVLRLGVQIIKVVQSMHNCGFLHRDLKPSNFAMGAGENAKTCFLLDFGLSRQYIMPT------GELKPPRGTTGFR--GTIRYASLNAHKGC--
  .. .. |   .|| .  .  |  .. ||||   |   |..    |.   |||||| .|         .. . .... | .    ||  .. . . .  
--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSR-DIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

-----------------DLGRQDDL------WSVFYMLVELANGSLPWKTLR----EKEDVGKAKLHYNHHKLITTLPHEFNAYLEYLQQLTYYDKPNYA
                  .| |          | . ..  . .|  . .                          . | |     .   .    | |. .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------FVCCPDEMYQIMKQCWHEDPEDRPTFS

YLIELF
 ..|.|
EIHECF