Gene AqueK095 (A.queenslandica)

AqueK095

Species: A.queenslandica
Alias: AqueK095
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK10

Sequence

Name Sequence Type Origin Length Description Download
AqueK095.AA Protein None 986 None Fasta, JSON
AqueK095.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of AqueK095.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK095.AA CDK10 41-325 63 9.90000000001e-171 573.48 In-house 1-285 (285) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-285/285
Sequence Identity: 63% (180 aa)

FNKLNRIGEGTYGVVYRAEDKKSKEIVALKRIRMENEEEGLPICSVREIGLLLSLSHENIVQLKEIAVGRELDNMFLVMNYCEQDLASLIDNMASPFTEP
| ||||.||||||.|||| | .|.||||||..||. | .|||| ..||| ||. . |||||.|.|. ||..|| .||||.|||||||||.|||..|||| 
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMPQPFTET

QVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGILKIADFGLARTLGRPLKPLTPTVVTLWYRAPELLFGSREYSCSLDMWSVGCIFGELLLNKPL
||||||||.| || |||.| .|||||||||||.|||| .|.|||||||  | | ||.|| .|||||||||||.|.|.   ..||| |||| ||||..|||
QVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHKPL

LPGKSEANQIELITNLIGSPNEGIWPGYSKLPLVASLEIKRQPYNNLKEKVYWISETGRGLLNDLLTYNPEYRMSSSRALRCKYF
.|| ||  ||..| .|.|.|.| ||||.|.||.|    .|.|||||||.|  |.|..|| ||| |. |||  |  .  .|. .||
MPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase AqueK095.AA PITSLRE 41-325 54 1.5e-166 559.61 In-house 1-295 (295) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-295/295
Sequence Identity: 54% (160 aa)

FNKLNRIGEGTYGVVYRAEDKKSKEIVALKRIRME--NEEEGLPICSVREIG-LLLSLSHENIVQLKEIAVGRELDNMFLVMNYCEQDLASLIDNMA---
| .||||.|||||||||| ||.  |||||||. ||   | || || |.|||  .|  | |.|||..||| .|  .|  ..||.| | ||.||..||    
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

SPFTEPQVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGILKIADFGLARTLGRPLKPLTPTVVTLWYRAPELLFGSREYSCSLDMWSVGCIFGEL
 ||.....|| |.||| | ...| | ..||||| ||||.. ||||||.||||||  | |.||.|| |||||||||||| |...||  .|||||||||.|.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

LLNKPLLPGKSEANQIELITNLIGSPNEGIWPGYSKLPLVASLE-IKRQPYNNLKEKVY---WISETGRGLLNDLLTYNPEYRMSSSRALRCKYF
.. |||..|||| .||. | .. | |.| ||||...||..  .. .. .|||||....     ||.||  ||| .|||||. |.. | ||   .|
ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase AqueK095.AA CDK 41-325 42 2.7e-154 497.18 In-house 1-284 (284) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-284/284
Sequence Identity: 42% (135 aa)

FNKLNRIGEGTYGVVYRAEDKKSK-----EIVALKRIRMEN-----EEEGLPICSVREIGLLLSLSHENIVQLKEIAVGRELD---------NMFLVMNY
. ||..||||||||||.| ||...     .|||||.|||||     |.||.|| ..||| ||  | |.|||.|... .. ..|         . ..|. |
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CEQDLASLIDNMASPFTEPQVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGI-----LKIADFGLARTLGR------PLKPLTPTVVTLWYRAPE
...||....|          .||.|.|||.||.|.| |...||||| .|.|....|.     ||||||||||  |       |....|. ||||||||||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

LLFGSREYS--CSLDMWSVGCIFGELLL---NKPLLPGKSEANQIELITNLIGSPNEGIWPGYSKLPLVASLEIKRQPYNNLKEKVYWISETGRGLLNDL
||.||..||  .. |||||||||.|...   .|||.||.|| .|...| ...|.|.| .||| .|||.                           ||| .
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKM

LTYNPEYRMSSSRALRCKYF
|.|.|. |.|.. || ..||
LCYDPKKRISAEQALQHPYF
Kinase AqueK095.AA CDC2 41-325 40 7.4e-124 382.7 In-house 1-301 (301) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-301/301
Sequence Identity: 40% (123 aa)

FNKLNRIGEGTYGVVYRAEDKKSKEIVALKRIRMENEEEG--LPICSVREIGLLLSLS-HENIVQLKEIAVGRELDNMFLVMNYCEQDLASLID-NMA--
. |...||||||||||...|.....|||||.|| |.|.||   |  ..||| .|  |  |.|||.|... .     . ..|  |...||  . |      
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

SPFTEPQVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGILKIADFGLARTLGRPLKPLTPT--VVTLWYRAPELLFGSREYSCSLDMWSVGCIFG
.....  || .| |.|.|....| . ..||||| .|.|. .|| .|||||||||. | |....|.   ||||||||||.|.|.. ||.. ||||.|||| 
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFA

EL---LLNKPLLPGKSEANQIELITNLIGSPNEGIWPGYSKLP-------LVASLEIKRQPYNNLKEKVY-WISETGRGLLNDLLTYNPEYRMSSSRALR
|.     .||| .|.||  |.  |   .|.||| .||| ..||             .... .||.|.|    . ..|. ||. .| |.|. | |. .||.
EMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQ

CKYF
 .||
HPYF
Kinase AqueK095.AA CMGC 41-325 23 8.70000000001e-123 405.6 In-house 1-513 (513) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-513/513
Sequence Identity: 23% (123 aa)

FNKLNRIGEGTYGVVYRAED--------------KKSKEIVALKRIR---MEN------EEEGLPICSVREIGLLLSLS-----------------HENI
. ....||||||||||.. |              ....||||.|.|.   .|.      |..|.|| . ||| .|  |.                 |.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VQLKEIAVGRELD---------------NMFLVMNYCEQDLASLIDNMAS--------PFTEPQ------------VKCIM------LQLLEGLS--YLH
|.|..| . .. |               ...||. |...||. .|.|.          |..| .            .|..|       |.|.||   |.|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

NNH--VIHRDLKVSNLLLTDK--------------------GILKIADFGLARTLGRP---------------------LKPLTPTVVTLWYRAPELLFG
 .   .|||||| .|.|....                    |.|||.|||||| .. .                     ..|.|. |||.||||||.|.|
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

SREYS---------CSLDMWSVGCIFGELLLN--------KPLLPGKSE-----------ANQIELITNLIGSPN---------------EGIWPGYSKL
...|.         .. |||||||||.|....        ||| ||.||            .|...| ...|.|.               | .||...||
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

P-------------------------LVASLEIKRQPYNNLKEKVYW-----------------------------------ISETGRGLLNDLLTYNPE
|                         .   .  ...|....|... |                                   ... .. ||. .|.|.|.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

YRMSSSRALRCKYF
 |.. . ||.  ||
KRITAEQALQHPYF
Kinase AqueK095.AA CDK7 41-325 38 7e-117 312.88 In-house 1-288 (288) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-288/288
Sequence Identity: 38% (111 aa)

FNKLNRIGEGTYGVVYRAEDKKSKEIVALKRIR----MENEEEGLPICSVREIGLLLSLSHENIVQLKEIAVGRELDNMFLVMNYCEQDLASLIDNMASP
..|.  ||||....||.| |... .||| |.|.     .  . |.    .||| .|  ..|.|.. |  |     ..|  ||. . . ||   |      
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFM--HKSNIQLVFDFMDWDLEVVIKDKSII

FTEPQVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGILKIADFGLARTLGRPLKPLTPTVVTLWYRAPELLFGSREYSCSLDMWSVGCIFGELLL
.|   .| .|...| || |.| | . |||||  |||.   |.||||||||||  | | . .|. ||| |||||||||| | |  . ||||||||| ||.|
LTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELML

NKPLLPGKSEANQIELITNLIGSPNEGIWPGYSKLPLVASLEIKRQPY---NNLKEKVYWISETGRGLLNDLLTYNPEYRMSSSRALRCKYF
  | ||| |.  |.. | . .| |.|  ||. ....    ...| .|      |..     |.    |.  ..| ||  |.. . .|  .||
RVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMM--DYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase AqueK095.AA CDK5 41-325 42 3.9e-114 362.15 In-house 1-287 (287) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-287/287
Sequence Identity: 42% (124 aa)

FNKLNRIGEGTYGVVYRAEDKKSKEIVALKRIRMENEEEGLPICSVREIGLLLSLSHENIVQLKEIAVGRELDNMFLVMNYCEQDLASLIDNMASPFTEP
..|...|||||||.||.| .|...|||||||.|...| || |   .||| ||  | |.||| |  .        . ||  .| |||   .|..      .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEK--KLTLVFEFCDQDLKKYMDSCNGEMDMH

QVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGILKIADFGLARTLGRPLKPLTPTVVTLWYRAPELLFGSREYSCSLDMWSVGCIFGELL-LNKP
 .| .|.||| ||.. |..|| |||||  |||   .|.|| |||||||  | | .  .  |||||||.|  |.||. || | ||||.|||| |.    .|
IIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRP

LLPGKSEANQIELITNLIGSPNEGIWPGYSKLPLVA--SLEIKRQPYNN-LKEKVYWISETGRGLLNDLLTYNPEYRMSSSRALRCKYF
| || .. .|  .|  ..|.|.|  ||. .|||       .    | .  ... |   .|.|. ||. .| .||. |.|   ||.  ||
LFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase AqueK095.AA CRK7 41-325 36 1.6e-110 373.45 In-house 1-343 (343) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-343/343
Sequence Identity: 36% (124 aa)

FNKLNRIGEGTYGVVYRAEDKKSKEIVALKRIRMENE---EEGLPICSVREIGLLLSLSHENIVQLKEIAVG--------RELDNMFLVMNYCEQDLASL
. ... ||||||| || |..|. .|.||||..||.||   .|| || ..||| .| .| |.|||.|||| .         ..  . ..|  |   ||. |
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

IDNM-ASPFTEPQVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGILKIADFGLARTLGRPL--KPLTPTVVTLWYRAPELLFGSREY--------
 ..     | . |.||.| |||||. |.|.. ..|||.| ||.|.  .|..||||||||| .      .|.|  |.|||||.|||| |  .|        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------SCSLDMWSVGCIFGELLLNKPLLPGKSEANQIELITNLIGSPNEGIWPGYSKLPLVASLEIKRQPYNNLK
                                . ||||.|||.|||.  ||...|. |  |.|.|  . ||||   ||   |||.   .  |||    | 
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

EKVY------WISETGRGLLNDLLTYNPEYRMSSSRALRCKYF
| .|       ...    ||  .|...|. |.. . .|.. .|
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase AqueK095.AA S_TKc 41-325 28 6.9e-90 305.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-231/231
Sequence Identity: 28% (86 aa)

FNKLNRIGEGTYGVVYRAEDKKSKEIVALKRIRMENEEEGLPICSVREIGLLLSLSHENIVQLKEIAVGRELDNMFLVMNYCEQ---DLASLIDNMASP-
. .|. ||.|..|.||.. .||...|||.|.|.         .   ||| .| .  |.|||.|... .    |....|| ||..   || ..|... .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FTEPQVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGILKIADFGLARTLGRPLKPLTPTVVTLWYRAPELLFGSREYSC-SLDMWSVGCIF
    |.| .....| |....| |.|....|||||| .|.||..   .||.|||||| |       |  ..|.||.|||.|     |.. . |.||.|||.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

GELLLNKPLLPGKSEANQIELITNLIGSPNEGIWPGYSKLPLVASLEIKRQPYNNLKEKVYWISETGRGLLNDLLTYNPEYRMSSSRALR-------CKY
 |.|  .|. |      |.... ..||                                    |. .. ... .|...|| |..   ||.         .
YEMLCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPW

F
|
F
Kinase AqueK095.AA CDK4 41-325 38 2.3e-89 303.22 In-house 1-290 (290) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-290/290
Sequence Identity: 38% (115 aa)

FNKLNRIGEGTYGVVYRAEDKKSKEIVALKRIRMENEEE--GLPICSVREIGLLLSLS---HENIVQLKEIAVGRELDN----MFLVMNYCEQDLASLID
. ... |||| || |||| | ..  .||||..|  ..||  |.|.  .||| ..  |    | |||.|...    . |     . .|.  |..||. ..|
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

NMASP-FTEPQVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGILKIADFGLARTLGRPLKPLTPTVVTLWYRAPELLFGSREYSCSLDMWSVGCI
..  |   ....| .| ||| |. .|| . .||||||  |.|.|  | .|.|||||||. .   . ||| |||||||||| |  |  |    ||||||||
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMA-LTPVVVTLWYRAPEVLLQS-YYNTPVDMWSVGCI

FGELLLNKPLLPGKSEANQIELITNLIGSPNEGIWPGYSKLPLVASLEIKRQPYNNLKEKVYWISETGRGLLNDLLTYNPEYRMSSSRALRCKYF
| |.   .|| .|.||..| . |  ..| | |  ||  . ||. .    . .|   .   .  ... |  ||.  |.||.. |||  ..|   ||
FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLPWDHFPQRHPRPFKDF---CPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase AqueK095.AA PFTAIRE 41-325 38 1.4e-83 284.0 In-house 1-287 (287) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-287/287
Sequence Identity: 38% (112 aa)

FNKLNRIGEGTYGVVYRAEDKKSKEIVALKRIRMENEEEGLPICSVREIGLLLSLSHENIVQLKEIAVGRELDNMFLVMNYCEQDLASLIDNMASPFTEP
. ||.. |||.|  ||..  .  . .|||| ||.. .||| |   .||  ||  | | ||| |  |   .|.  . .|  | . ||.  .|         
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ-QEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKET--LTFVFEYVHTDLCQYMDKHPGGMHPN

QVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGILKIADFGLARTLGRPLKPLTPTVVTLWYRAPELLFGSREYSCSLDMWSVGCIFGELLLNKPL
 |.  . ||| |||| |  .| |||||  |||....| || |||||||    | .     ||||||| |  | || ||| .|||| ||||| |..  .|.
NVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPA

LPGK-SEANQIELITNLIGSPNEGIWPGYSKLPLVASLEIK--RQPYNNLKEKVYWIS--ETGRGLLNDLLTYNPEYRMSSSRALRCKYF
 ||     .| |.|  . |.|.|  ||| ..||      ..       .|.. .  |.    .  |....| ..|. |.|   |. ..||
FPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase AqueK095.AA Pkinase 41-325 29 4e-83 287.27 Pfam 1-293 (293) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-293/293
Sequence Identity: 29% (90 aa)

FNKLNRIGEGTYGVVYRAEDKKSKEIVALKRIRMENEEEGLPICSVR--EIGLLLSLSHENIVQLKEIAVGRELDNMFLVMNYCEQDLASLIDNM-----
. .. .||.|..|.||.. .|.. .|||.|.|. ..|... ..  .|  || ....|.|.|||.|...      |.. .|| ||| .|  ..| .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLY-VMDLFDYIST

--ASPF--TEPQVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGIL----KIADFGLARTL-GRPLKPLTPTVVTLWYRAPELLFGSREYSCSLDM
    .|  .| ..|..|.|.|.|| |.|.. .|||||| .|.|. ..| .    ||.|||||. .   .   .|  ..|.||.|||.. |...|. . ||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSVGCIFGELLLNKPLLPGK----SEANQIELITNLIGSPNEGIWPGYSKLPLVASLEIKRQPYNNLKEKVYWISETGRGLLNDLLTYNPEYRMSSSRAL
||.|||. |.|. .|. ||.    . ..|...| .  | |..  ||  .  ..   . . . .   .... . .||... .....|...|. | .   .|
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQIL

RCKYF
  ..|
QHPWF
Kinase AqueK095.AA Pkinase_Tyr 41-190 28 9.7e-20 67.48 Pfam 1-161 (270) Show / Hide 
Range on Protein: 41-190
Range on HMM: 1-161/270
Sequence Identity: 28% (47 aa)

FNKLNRIGEGTYGVVYRAEDK----KSKEIVALKRIRMENEEEG---LPICSVREIGLLLSL-SHENIVQLKEIAV-GRELDNMFLVMNYCEQ-DLASLI
  ..  .||| .|.||... |    . |  || | ..    .|        .  |. .. .| .|.|||.|  . .  .|  ....|| |..  || .  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR--EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

DNM---ASPFTEPQVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGILKIADFGLARTL
 .      |.| ..  .. .|  .|..||.... |||||   | |.|.... ||.||||||..
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase AqueK095.AA TyrKc 41-325 20 4.8e-13 -11.74 SMART 1-280 (280) Show / Hide 
Range on Protein: 41-325
Range on HMM: 1-280/280
Sequence Identity: 20% (64 aa)

FNKLNRIGEGTYGVVYRAEDKKSKEIVALKRIRMENEEEGLPICSVREIGLLLSL--SHENIVQLKEIAVGR-----ELDNMFLVMNYCEQ-DLASLIDN
  ..  .||| .|.||... |   . || | .. .  .| .     ||. .. .|  .|.|||.|  ...       . . ...|| |..  || . . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDF----MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

MASPFTEPQVKCIMLQLLEGLSYLHNNHVIHRDLKVSNLLLTDKGILKIADFGLARTLGRP--------LKP-----LTPTVVTLWYRAPELLFGSREYS
    .. ..   ...|  .| .||| ...|||||   | |...... ||.||||.| ..           .       . |.. .   ||| .   ....
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

CSLDMWSVGCIFGELLLNKPLLPGKSEANQIELITNLIGSPNEGI----WPGYSKLPLVASLEIKRQPYNN-------LKEKVYWISETGRGLLNDLLTY
   | || |    |..                    . ..| .|.     . .  . .| . .  .|| |.         ...|      . .  .   .
TKSDVWSFGVCMWEIF-------------------TYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMY------Q-IMKQCWHE

NPEYRMSSSRALRCKYF
.|| | . |    ...|
DPEDRPTFSEI--HECF