Gene AqueK103 (A.queenslandica)

AqueK103

Species: A.queenslandica
Alias: AqueK103
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: PCTAIRE

Sequence

Name Sequence Type Origin Length Description Download
AqueK103.AA Protein None 505 None Fasta, JSON
AqueK103.kin_dom Protein Kinase Domain None 282 None Fasta, JSON

Protein domain

Protein domains of AqueK103.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK103.AA PCTAIRE 173-454 69 3.2e-197 661.49 In-house 1-291 (291) Show / Hide 
Range on Protein: 173-454
Range on HMM: 1-291/291
Sequence Identity: 69% (202 aa)

YEKLEKLGEGTYATVYKGKSNITGKLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVFLHDIIHTARSLTLIFEYVEQDLKQYLDQCSGMMAMPNVK
| ||.||||||||||||..|  |. ||||||||||||||||||||||||||||||||||| ||||||| ..|||.||| ..|||||.|.|  .| | |||
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNMHNVK

LFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDLKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSIDYADSIDMWGVGCIFYEMIVGRPMFPG
||||||.||| ||| ||||||||||||||| |.| ||||||||||||||||||||.|||||||||||||.|| ||  .|||||||||||||  |||.|||
LFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLFPG

AN------VEEELVLIWKSLGTPNEKTWPGITKNKEFISHSFLRYDPQPLGLIVPRLD---KEGINLMSKLLSYESQERLLARDGMKHNYF
        |...| .| . |||| ||||||.. |.|| . .| || .|||    ||||   |....|...|| |||..|. | . ||| ||
STDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase AqueK103.AA PFTAIRE 173-454 61 2.5e-187 628.6 In-house 1-287 (287) Show / Hide 
Range on Protein: 173-454
Range on HMM: 1-287/287
Sequence Identity: 61% (177 aa)

YEKLEKLGEGTYATVYKGKSNITGKLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVFLHDIIHTARSLTLIFEYVEQDLKQYLDQCSGMMAMPNVK
||||||||||.|||||||.| |....||||||||. |||.|.|||||.||||.||||||| ||||||| . ||..||||. ||.||.|.. | | . ||.
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQQEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNVR

LFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDLKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSIDYADSIDMWGVGCIFYEMIVGRPMFPG
||||||.||| ||| |..|||||||||||||. | |||||||||||||||..|||.|||||||||||||||| .|  ..||||||||| ||. |.|.|||
LFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFPG

A-NVEEELVLIWKSLGTPNEKTWPGITKNKEFISHSFL--RYDPQPLGLIVPRLD--KEGINLMSKLLSYESQERLLARDGMKHNYF
  .. . | .|.| ||||.| ||||...  ..  | |    | |..|. ..||..   .. .||.|.| .| ..|. | . |.|.||
MKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase AqueK103.AA CDK5 173-454 54 7.70000000001e-170 541.27 In-house 1-287 (287) Show / Hide 
Range on Protein: 173-454
Range on HMM: 1-287/287
Sequence Identity: 54% (156 aa)

YEKLEKLGEGTYATVYKGKSNITGKLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVFLHDIIHTARSLTLIFEYVEQDLKQYLDQCSGMMAMPNV
|||.||.|||||.||||..   |. .||||..||. | || |.|||||..||| ||| ||| |||.||. . |||.||.. |||| |.|.| | | |. .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KLFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDLKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSIDYADSIDMWGVGCIFYEMI-VGRPMF
| |..||..||..||....||||||||||||. .| |||||||||||  .| ..|| |||||||||||||.||  |  ||||| .|||| ||.  |||.|
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

PGANVEEELVLIWKSLGTPNEKTWPGITKNKEFI--SHSFLRYDPQP-LGLIVPRLDKEGINLMSKLLSYESQERLLARDGMKHNYF
||..||..| .| | .|||.| .||.|||  ..    . .  |.... .  |||.||..| .|..|.| .. ..|. | ....| ||
PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase AqueK103.AA CDK 173-454 43 1.7e-161 520.59 In-house 1-284 (284) Show / Hide 
Range on Protein: 173-454
Range on HMM: 1-284/284
Sequence Identity: 43% (139 aa)

YEKLEKLGEGTYATVYKGKSNITG-----KLVALKEIRLEH-----E-EGAPCTAIREVSLLKDLKHANIVFLHDIIHTA-----------RSLTLIFEY
||||||.|||||..|||... .||     ..||||.||.|.     | || |.|||||.||||.| |.||| |||..||            ..|...|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

VEQDLKQYLDQCSGMMAMPNVKLFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGD-----LKLADFGLARAKSV------PTKTYSNEVVTLWYRPPD
...|||.|.|          .| ...||.||| ||||..|.||||||||.||...|      ||.||||||||...      |..||..||||||||.|.
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

VLLGSIDYA--DSIDMWGVGCIFYEMIV---GRPMFPGANVEEELVLIWKSLGTPNEKTWPGITKNKEFISHSFLRYDPQPLGLIVPRLDKEGINLMSKL
.|||| .|    .||||.|||||.||.    ..|.||| .  . | .| . .|||.|..|||.||  ..                         .|..|.
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKM

LSYESQERLLARDGMKHNYF
| |. . |. | . ..| ||
LCYDPKKRISAEQALQHPYF
Kinase AqueK103.AA CDC2 173-454 47 2.9e-143 443.45 In-house 1-301 (301) Show / Hide 
Range on Protein: 173-454
Range on HMM: 1-301/301
Sequence Identity: 47% (143 aa)

YEKLEKLGEGTYATVYKGKSNITGKLVALKEIRLEHEEGA---PCTAIREVSLLKDLK-HANIVFLHDIIHTARSLTLIFEYVEQDLKQYLD-QCSG--M
|.|.||.|||||  |||.| . |...|||| ||||.|.     | ||||| |.||.|| | ||| |||.||  ..| ..|||...|||.|.| . .    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

MAMPNVKLFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDLKLADFGLARAKSVPTKTYS--NEVVTLWYRPPDVLLGSIDYADSIDMWGVGCIFYEM
|   .|| ...|. .|. .||.|.|.||||||||.||...|..|.|||||||| ..| .||    ||||||||.| .|||. .|  ..||| .||||.||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---IVGRPMFPGANVEEELVLIWKSLGTPNEKTWPGITKNKEFISHSFLRYDPQPLGLIVPR---------LDKEGINLMSKLLSYESQERLLARDGMKH
   .  .|.|.|    ..|  | . ||||||.||||.|.....   .| |. || |  |.|.         ||.||| | ...| |. | |. |.. ..|
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDY-KNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQH

NYF
 ||
PYF
Kinase AqueK103.AA CMGC 173-454 24 6.2e-126 416.15 In-house 1-513 (513) Show / Hide 
Range on Protein: 173-454
Range on HMM: 1-513/513
Sequence Identity: 24% (125 aa)

YEKLEKLGEGTYATVYKGKSNITG--------------KLVALKEIRLE----------HEEGAPCTAIREVSLLKDLK-----------------HANI
||...|.|||||..|||.. . |.              ..||.| |...          ...| |..|.||...|| |.                 | ||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VFLHDIIHTAR-----------------SLTLIFEYVEQDLKQYLDQCS------GMMAM-------------PNVKLFL------FQLMRGLQ--YCHS
| |.||...                   .| |.|||...||.||.....      . | .             .|.| |.      .|. |||   ||||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHS

RK--ILHRDLKPQNLLISEQGDL--------------------KLADFGLARAKSVP---------------------TKTYSNEVVTLWYRPPDVLLGS
..  |.||||||.|.||.....|                    |..||||||. ...                     ...|...|||.|||.| .|||.
HWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGW

IDYA---------DSIDMWGVGCIFYEMIVG--------RPMFPGANV-----------EEELVLIWKSLGTPN---------------EKTWPGITKNK
 .|           .||||.|||||.||. |        .|.||| .             . | .| | ||||.               |..||...|. 
KHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLP

EFIS-------------HS------------FLRYDPQPLGLIVPR-----------------------------------LDKEGINLMSKLLSYESQE
...              .|            | .. |.|.  ..|.                                   .|...|.|..|.| |. ..
WYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDK

RLLARDGMKHNYF
|. | . ..| ||
RITAEQALQHPYF
Kinase AqueK103.AA CDK7 173-454 36 2.7e-110 294.99 In-house 1-288 (288) Show / Hide 
Range on Protein: 173-454
Range on HMM: 1-288/288
Sequence Identity: 36% (107 aa)

YEKLEKLGEGTYATVYKGKSNITGKLVALKEIR-----LEHEEGAPCTAIREVSLLKDLKHANIVFLHDIIHTARSLTLIFEYVEQDLKQYLDQCSGMMA
|||....|||..|||||.    ||. || |.|.      | . |   |||||. .|. ..| |.. | ||.    .. |.|.. . ||       |  . 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

MPNVKLFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDLKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSIDYADSIDMWGVGCIFYEMIVGR
  ..| .  .. .|| |||   |||||||| |||..| |.||.|||||||.   | . |.  ||| ||| |  | |   |  ..||| ||||| | .   
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV

PMFPGANVEEELVLIWKSLGTPNEKTWPGITKNKEFISHSFLRYDP---QPLGLIVPRLDKEGINLMSKLLSYESQERLLARDGMKHNYF
| .|| .    |. | . ||||.|..||.... ...|   |  . .    ||  |      . . ||....  . ..|. ...  |. ||
PYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYI--KFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase AqueK103.AA PITSLRE 173-454 37 2.9e-93 316.14 In-house 1-295 (295) Show / Hide 
Range on Protein: 173-454
Range on HMM: 1-295/295
Sequence Identity: 37% (112 aa)

YEKLEKLGEGTYATVYKGKSNITGKLVALKEIRLE---HEEGAPCTAIREVS-LLKDLKHANIVFLHDII--HTARSLTLIFEYVEQDLKQYLDQCS---
...| . .||||  ||..|   |.  |||| . .|     || | |..||.. .|. |.| ||| .  |.   .  .  ...|||| |||  ..  .   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

GMMAMPNVKLFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDLKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSIDYADSIDMWGVGCIFYEM
     . .| .. || || .. |. .|.|||||  |||.| .| ||..||||||    | | |.  ||||||| | .|||.  |   .||| ||||| |.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

IVGRPMFPGANVEEELVLIWKSLGTPNEKTWPGITKNKEFISHS-FLRYDPQPLGLIVP---RLDKEGINLMSKLLSYESQERLLARDGMKHNYF
| ..|.|.| .  ...  | | .|||.|| |||.|. . .     |  | .  |  ..|   ..   |  |. ..| |  ..|. | |..|| .|
ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase AqueK103.AA S_TKc 173-454 27 1.8e-91 311.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 173-454
Range on HMM: 1-231/231
Sequence Identity: 27% (82 aa)

YEKLEKLGEGTYATVYKGKSNITGKLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVFLHDIIHTARSLTLIFEYVEQ---DLKQYLDQCSGM----
||.|.|.|.|....|||.. . ||..||.|.|.        ....||...||  .| ||| |.|....  .| ...||...   ||..|.... .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-MAMPNVKLFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDLKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSIDYAD-SIDMWGVGCIFYEM
 .    .. .. |. ..|.||||..|.||||||.|.|..|   .|..||||||         .  ..|.||..| ||     |   ..|.| .|||.|||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

IVGRPMFPGANVEEELVLIWKSLGTPNEKTWPGITKNKEFISHSFLRYDPQPLGLIVPRLDKEGINLMSKLLSYESQERLLARDGMK-------HNYF
..|.| ||      .. ...| .|                                    ..|......|.| .. ..|. | . ..       | .|
LCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK103.AA CDK4 173-454 40 1.5e-90 307.17 In-house 1-290 (290) Show / Hide 
Range on Protein: 173-454
Range on HMM: 1-290/290
Sequence Identity: 40% (120 aa)

YEKLEKLGEGTYATVYKGKSNITGKLVALKEIRLE-HEE--GAPCTAIREVSLLKDLK---HANIVFLHDIIH---TAR---SLTLIFEYVEQDLKQYLD
|...  .||| | |||.  . .||. |||| .|    ||  | |   |||.|... |.   |.||| | |. |   | |    .|..|| ...||..|||
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

QCSG-MMAMPNVKLFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDLKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSIDYADSIDMWGVGCI
.|    |  . .|   .||.||. . ||  | ||||||||.|.. .| .|||||||||  |  ..  .  ||||||| | ||| |  |.  .||| ||||
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMALTPV-VVTLWYRAPEVLLQSY-YNTPVDMWSVGCI

FYEMIVGRPMFPGANVEEELVLIWKSLGTPNEKTWP-GITKNKEFISHSFLRYDPQPLGLIVPRLDKEGINLMSKLLSYESQERLLARDGMKHNYF
| ||   || |.| .  . |  | .  |.| |. ||  .    .    .|  . |.|.  ..| ..| |. |. | |.|. . |. |. . .| ||
FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLPWD----HFPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase AqueK103.AA CRK7 173-399 36 3.4e-80 272.74 In-house 1-282 (343) Show / Hide 
Range on Protein: 173-399
Range on HMM: 1-282/343
Sequence Identity: 36% (104 aa)

YEKLEKLGEGTYATVYKGKSNITGKLVALKEIRLEHE----EGAPCTAIREVSLLKDLKHANIVFLHDIIHT---------AR-SLTLIFEYVEQDLKQY
||...  |||||  ||| | . ||..|||| .|...|    || | |||||. .|. |.|.||| |..|.            . |  ..|||.  ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LDQCSG-MM--AMPNVKLFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDLKLADFGLARAKSVPT--KTYSNEVVTLWYRPPDVLLGSIDY------
|.  |. |   .  ..| |. ||. |..||| ...||||.|  |.|.  || .|.|||||||        . | | |.|||||||  |||   |      
LE--SKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHIL

--------------------------------ADSIDMWGVGCIFYEMIVGRPMFPGANVEEELVLIWKSLGTPNEKTWPGITK
                                  .||||..|||. |  ...|.|.| |  . | .| |  |.||   || ..|
KELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMK
Kinase AqueK103.AA Pkinase 173-454 31 4.1e-79 273.95 Pfam 1-293 (293) Show / Hide 
Range on Protein: 173-454
Range on HMM: 1-293/293
Sequence Identity: 31% (95 aa)

YEKLEKLGEGTYATVYKGKSNITGKLVALKEIRLEHEEG-APCTAIR--EVSLLKDLKHANIVFLHDIIHTARSLTLIFEYVEQ-----DLKQYLD-QCS
|....|.|.|....|||..   |||.||.|.|...||.   . |..|  |....| |.| ||| |.|. .. ... ...||.|      ||. |.  . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GMM--AMPNVKLFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDL----KLADFGLARAK-SVPTKTYSNEVVTLWYRPPDVLLGSIDYADSIDMWGV
| .   .  .| .. |. |||.||||..|.||||||.|.||...|..    |..|||||. .   .   ..  ..|.||..| |..|. .|  ..|||..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCIFYEMIVGRPMFPGA----NVEEELVLIWKSLGTPNEKTWPGITKNKEFISHSFLRYDPQPLGLIVPRLDKEGINLMSKLLSYESQERLLARDGMKHN
|||.|||. ||| |||.    |  .....| . .|.|..  ||    .  |   .. .   . . .  .....|.. .....| .  ..|. |.. ..| 
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

YF
.|
WF
Kinase AqueK103.AA Pkinase_Tyr 173-318 30 8.6e-17 57.5 Pfam 1-160 (270) Show / Hide 
Range on Protein: 173-318
Range on HMM: 1-160/270
Sequence Identity: 30% (50 aa)

YEKLEKLGEGTYATVYKGKSN----ITGKLVALKEIRLEHEEGAPCTA------IREVSLLKDL-KHANIVFLHDIIH-TARS--LTLIFEYVEQ-DLKQ
 ....||||| . .||||. .     |.  || | ..    |||   .      .||....| | .| ||| |. ..    ..  . ...||..  ||. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

YLDQC---SGMMAMPNVKLFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDLKLADFGLARA
|| .     .   |.    . .|  .|..| .|... ||||   | |..|..  | .||||||.
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase AqueK103.AA TyrKc 173-404 21 1.6e-11 -36.43 SMART 1-280 (280) Show / Hide 
Range on Protein: 173-404
Range on HMM: 1-280/280
Sequence Identity: 21% (61 aa)

YEKLEKLGEGTYATVYKGKSNITGKLVALKEIRLEHEEGAPCTAI-REVSLLKDL--KHANIVFLHDIIHTA-------RSLTLIFEYVEQ-DLKQYLDQ
 ....||||| . .||||. .     || | .. ..       .. || .... |  .| ||| |. .. .          | ...||..  |||.||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

CSGMMAMPNVKLFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDLKLADFGLARAKSVP------TKTYS-----NEV--VTLWYRPPDVL-------
. .   |.    | .|  .| .| ||... ||||   | |..|..  | .||||.|.          ...|.     ..   . .   .| ..       
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

----------------LGSIDYAD---SIDMWGVGCIFYEMIVGRPMFPGAN--------VEEELVLIWKSLGTPNEKTWPGITKNKEFI
                .|   | .      |     ..     |. | . .|          .|.  | |.    . .  |  .  .|..
KSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK103.AA CRK7 423-454 28 0.025531 3.57 In-house 312-343 (343) Show / Hide 
Range on Protein: 423-454
Range on HMM: 312-343/343
Sequence Identity: 28% (9 aa)

LDKEGINLMSKLLSYESQERLLARDGMKHNYF
..||  .|. |.| .  . |  | .   | .|
MPKECLDLLDKMLCLDPKKRFTAEECLQHDWF