Gene AqueK107 (A.queenslandica)

AqueK107

Species: A.queenslandica
Alias: AqueK107
External Links:
Annotation:

Classification

Group: CMGC
Family: CDKL

Sequence

Name Sequence Type Origin Length Description Download
AqueK107.AA Protein None 641 None Fasta, JSON
AqueK107.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of AqueK107.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK107.AA CDKL 4-287 65 9.90000000001e-207 693.07 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-286/286
Sequence Identity: 65% (186 aa)

YENLGLVGEGSYGMVMKCRHKDSSQLVAIKKFLETENDRMVKKIALREVRMLKQLRHENLVNLIEVFRRKKRLYLVFEFVDHTALDELDKYPSGADESLV
||.||.|||||||.|||||.|.. |.||||||.|.|.|.||||||.||..|||||.|||.||||||||||..|.||||..||| |.||..||.| ||..|
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEEYPNGVDEHVV

KKIMWQVLKGVEFCHQHNVIHRDVKPENILIS-KRGVVKICDFGFARAIAPPGEAYTDYVATRWYRAPELLVGDTNYGRAVDVWAIGCLFSEMLTGEPLF
.|.|||.||...|||.||.||||.|||||||. | |.||.||||||| .| |||.|||||||||||||||||||| || .||.|||||.. ||..|.||.
RKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLW

PGESDIDQLYLITKCFGNLIARHREVFSRNPLFIGMRLPEAREIQPFERRYHRLS-PAAMDIIKWSLRLDPADRPTCTQLLKHELF
||.|||||||.| ||.|.||.|| |.|| ||.|.||..||  . .| |.||  .| ..|.|..|  | .||..|.||.||..|..|
PGQSDIDQLYHIQKCLGPLIPRHQEIFSKNPFFHGMKFPEIEHMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase AqueK107.AA CMGC 4-287 24 2.2e-123 407.61 In-house 1-513 (513) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-513/513
Sequence Identity: 24% (124 aa)

YENLGLVGEGSYGMVMKCRH--------------KDSSQLVAIKKFLETENDRMVKK----------IALREVRMLKQLR-----------------HEN
||... .|||.||.| |||.              ... ..|||||. . . .   .|          .||||...||.|.                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

LVNLIEVFRRKK-----------------RLYLVFEFVDHTALDELDKYPS--------GADESL------------VKKIM------WQVLKGVE--FC
.|.|...|..|.                  ||||||..||. .. .....         . .|              .|..|      .|.|.|..  .|
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HQHN--VIHRDVKPENILISKR--------------------GVVKICDFGFARAIAPP---------------------GEAYTDYVATRWYRAPELLV
|.|.  .|||| |||||||...                    |..||||||.||.. |.                     ...||.||.||||||||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GD---------TNYGRAVDVWAIGCLFSEMLTG--------EPLFPGESD-----------IDQLYLITKCFGNLI---------------AR-------
|.         ..|. ..|.|..|| | ||.||        .|||||.|.           ||||..| | .|.                  .       
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

------------------HREVFSRNPLFIGMRLPEAREI--QPFERRYHR--------------------------------LSPAAMDIIKWSLRLDP
                  |   | ||..... |.|. . .  .... ....                                ..| | | .|  |..||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

ADRPTCTQLLKHELF
..|.|. | |.|. |
DKRITAEQALQHPYF
Kinase AqueK107.AA Pkinase 4-287 33 3.8e-106 363.72 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-293/293
Sequence Identity: 33% (100 aa)

YENLGLVGEGSYGMVMKCRHKDSSQLVAIKKFLETENDRMVKKIALR--EVRMLKQLRHENLVNLIEVFRRKKRLYLVFEFVDHT----ALDELDK--YP
|. .. .|.||.| | ||.||.....||.|..   ...  ......|  |....| |.|.| | |...|..|...|.|.|.....     | .. .  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SGA--DESLVKKIMWQVLKGVEFCHQHNVIHRDVKPENILISKRGVV----KICDFGFARAI-APPGEAYTDYVATRWYRAPELLVGDTNYGRAVDVWAI
 .   .|  .|..|.|.|.|.|.||....||||.|||||||...|..    ||||||.|. .   ... .|... |.||.|||.. |.. ||..||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCLFSEMLTGEPLFPGE----SDIDQLYLITKCFGNLIARHREVFSRNPLFIGMRLPEAREIQPFERRYHRLSPAAMDIIKWSLRLDPADRPTCTQLLKH
||.. |||.|.|.|||.    . .||...| .  |  . ....  .....|   |  . .  . .... |..|... |.||| |..||..|||..|.|.|
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQH

ELF
. |
PWF
Kinase AqueK107.AA CDK 4-219 39 1.4e-105 338.78 In-house 1-242 (284) Show / Hide 
Range on Protein: 4-219
Range on HMM: 1-242/284
Sequence Identity: 39% (100 aa)

YENLGLVGEGSYGMVMKCRHKDSS-----QLVAIKKF-LETE----NDRMVKKIALREVRMLKQLRHENLVNLIEVFRRK-----------KRLYLVFEF
|| |  .|||.|| | |.|.|..      |.||.||. .|.|     .  .   |.||. .||.| |.| |.|..|.  |           ..||.|||.
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

VDHT---ALDELDKYPSGADESLVKKIMWQVLKGVEFCHQHNVIHRDVKPENILISKRGV-----VKICDFGFARAIAP------PGEAYTDYVATRWYR
.||     .|             .| .||| |.|...||.....||| || ||||...|.     .|| |||.|||         |  .||  | |.|||
MDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYR

APELLVGDTNYG--RAVDVWAIGCLFSEMLT---GEPLFPGESDIDQLYLITKCFG
||||| |...|.   ..|.|..|| |.||.|   ..|||||.|.|||| .| . .|
APELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICG
Kinase AqueK107.AA S_TKc 4-287 31 8.8e-99 335.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-231/231
Sequence Identity: 31% (93 aa)

YENLGLVGEGSYGMVMKCRHKDSSQLVAIKKFLETENDRMVKKIALREVRMLKQLRHENLVNLIEVFRRKKRLYLVFEFVDH---TALDELDKYPSG---
|| | ..|.|..| |.|||||.. ..||||.           . ..||...||. .|.|.|.|..||.  ..||.|.|..|.   . .| ..|....   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--ADESLVKKIMWQVLKGVEFCHQHNVIHRDVKPENILISKRGVVKICDFGFARAIAPPGEAYTDYVATRWYRAPELLVGDTNYGR-AVDVWAIGCLFSE
   .|  ....|.|.....|.||.|..||||.||||||...  ..||||||.|| .       | .. |.||.|||.|     ||. ..|.|..||.. |
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MLTGEPLFPGESDIDQLYLITKCFGNLIARHREVFSRNPLFIGMRLPEAREIQPFERRYHRLSPAAMDIIKWSLRLDPADRPTCTQLLK-------HELF
||.|.|.||   ...... . .                                        || | |.|.  |. ||..|||. ..|.       |. |
MLCGYPPFP---QMQMMFKKIG----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK107.AA CDC2 4-214 45 3.2e-95 293.09 In-house 1-221 (301) Show / Hide 
Range on Protein: 4-214
Range on HMM: 1-221/301
Sequence Identity: 45% (102 aa)

YENLGLVGEGSYGMVMKCRHKDSSQLVAIKKF-LETENDR-MVKKIALREVRMLKQLR-HENLVNLIEVFRRKKRLYLVFEFVDHTALDELD-KYP--SG
|. .  .|||.|| | ||..... |.||.||. ||.|..   |   |.||   || |. |.|.| | .|.   ..||.|||..|.     .| . |  . 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

ADESLVKKIMWQVLKGVEFCHQHNVIHRDVKPENILISKRGVVKICDFGFARAIAPPGEAYT--DYVATRWYRAPELLVGDTNYGRAVDVWAIGCLFSEM
 ...|||..|.| |.||.||||. ..||| || ||||.| |..|| ||| |||.  |  .||    | |.||||||.| |.  |  .||.|.|||.|.||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---LTGEPLFPGESDIDQLYLI
    | .|||.|.| ||||. |
FMDVTKKPLFHGDSEIDQLFKI
Kinase AqueK107.AA CDK7 4-219 39 4e-93 248.32 In-house 1-220 (288) Show / Hide 
Range on Protein: 4-219
Range on HMM: 1-220/288
Sequence Identity: 39% (90 aa)

YENLGLVGEGSYGMVMKCRHKDSSQLVAIKKFL----ETENDRMVKKIALREVRMLKQLRHENLVNLIEVFRRKKRLYLVFEFVDHTALDELDKYPSGAD
|| . ..||| .. | | . . . | |||||        | .  .   |.||. .|. ..|.| ..|| .|  |  ..|||.| | . |..  |     |
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMD-WDLEVVIK-----D

ESLV------KKIMWQVLKGVEFCHQHNVIHRDVKPENILISKRGVVKICDFGFARAIAPPGEAYTDYVATRWYRAPELLVGDTNYGRAVDVWAIGCLFS
 |..      | .| ..|.|.|.||.. . ||| || | |... |..|| ||| ||..  | ..||  | |||||||||| |   || .||.|..|| | 
KSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFA

EMLTGEPLFPGESDIDQLYLITKCFG
| .   | .||.||||||  | .  |
ELMLRVPYLPGDSDIDQLTRIFQTLG
Kinase AqueK107.AA CDK5 4-287 37 1.8e-85 269.97 In-house 1-287 (287) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-287/287
Sequence Identity: 37% (107 aa)

YENLGLVGEGSYGMVMKCRHKDSSQLVAIKKFLETENDRMVKKIALREVRMLKQLRHENLVNLIEVFRRKKRLYLVFEFVDHTALDELDKYPSGADESLV
|| .  .||| ||.| | | |..  .||.|.    ..|  |   |.||. .|| |.|.| | |. |    |.| |||||.|      .|.   . |  ..
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KKIMWQVLKGVEFCHQHNVIHRDVKPENILISKRGVVKICDFGFARAIAPPGEAYTDYVATRWYRAPELLVGDTNYGRAVDVWAIGCLFSEML-TGEPLF
| .|.| |||..|||.|.| ||| || | ||.|.|  |  ||| |||   |   |.  | | |||.|  | |   |   .|.| .|| | ||  .| |||
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

PGESDIDQLYLITKCFGNLIARHREVFSRNPLFI--GMRLPEAREIQPFERRYHRLSPAAMDIIKWSLRLDPADRPTCTQLLKHELF
|| .. ||| .| |  |     .    .  | .      .|     |...   ..|.   ||. .  |...|. | .  . |.|  |
PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase AqueK107.AA MAPK 4-216 34 2.6e-71 243.23 In-house 1-249 (328) Show / Hide 
Range on Protein: 4-216
Range on HMM: 1-249/328
Sequence Identity: 34% (87 aa)

YENLGLVGEGSYGMVMKCRHKD------SSQLVAIKKFLETENDRMVKKIALREVRMLKQL-RHENLVNLIEVFRRK-----------KRLYLVFEFVDH
|..|  .|.|.||.| ....|       . . |||||.    .. .  | ..||...|. . .||| ..|...|. .           . .|.|.|. ..
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

TALDELDKYPSGADESLVKKIMWQVLKG--VEFCHQHNVIHRDVKPENILISKRGVVKICDFGFARAIAP-PGEAY-------------TDYVATRWYRA
  |  . | .   ..  .. .|.|.|.|  . . |  |||||| ||.|||. . . .|||||| || |.|   . .             |.|||||||||
D-LHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRA

PELLVGD--TNYGRAVDVWAIGCLFSEMLT-GEPLFPGESDIDQLYLITK
||.. .   ..|  |||.|..|| | |||| . |||||.. |||. ||..
PEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIME
Kinase AqueK107.AA ERK7 4-287 34 3.8e-68 232.11 In-house 1-292 (292) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-292/292
Sequence Identity: 34% (101 aa)

YENLGLVGEGSYGMVMKCRHKDSSQLVAIKKFLETENDRMVKKIALREVRMLKQLR-HENLVNLIEVFRRK--KRLYLVFEFVDHTALDELDKYPSGADE
|| .  .| | ||.| |   | . | ||.||      ..       ||. .|.... |.|.. ||.|.| .  . .|||||| . | |    .  .   .
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFME-TDLHAVIRKGNILKD

SLVKKIMWQVLKGVEFCHQHNVIHRDVKPENILISKRGVVKICDFGFARAIAPPGE------AYTDYVATRWYRAPELLVGDTNYGRAVDVWAIGCLFSE
  .. ||.|.|. . . |  ||||||.|| |||.    .||.|||| || ||   |      . |.||||||||||| |.| ..| ..|| | |||   |
IHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGE

MLTGEPLFPGESDIDQLYLITKCFGNLIARH-REVFSRNPLFIGMRLPEAREIQPFERRYHRLSPAAMDIIKWSLRLDPADRPTCTQLLKHELF
||.| |.||| | ..|. .| .  ..  .     . |     .  ...  .. ....  .   ...|.|..|  | . |  | | .| |.|   
MLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMN-QQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase AqueK107.AA PFTAIRE 4-287 35 5.2e-64 218.96 In-house 1-287 (287) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-287/287
Sequence Identity: 35% (102 aa)

YENLGLVGEGSYGMVMKCRHKDSSQLVAIKKFLETENDRMVKKIALREVRMLKQLRHENLVNLIEVFRRKKRLYLVFEFVDHTALDELDKYPSGADESLV
||.|   |||||  | | . .   |.|| |     ...  .   | ||. .||.|.| | | |  .   |. | .|||.|.      .|| | | .   |
YEKLEKLGEGSYATVYKGISCINQQFVALKE-IRLQQEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNV

KKIMWQVLKGVEFCHQHNVIHRDVKPENILISKRGVVKICDFGFARAIAPPGEAYTDYVATRWYRAPELLVGDTNYGRAVDVWAIGCLFSEMLTGEPLFP
.  ..| | |  .|||  | |||.|| | |||. |  |  ||| |||   |   | . | | ||| |  | | |.|   .|.| .|| | ||..| |.||
RLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFP

GESDI-DQLYLITKCFGNLIARHREVFSRNPLFIGMRLP-EAREIQPFERRYHRLS--PAAMDIIKWSLRLDPADRPTCTQLLKHELF
| .|| ||| .| |  |          .. | .   ...    . .. .. . |..  | | |...  |.. | ||    . ..|. |
GMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase AqueK107.AA RCK 100-216 45 4.7e-54 169.75 In-house 102-228 (298) Show / Hide 
Range on Protein: 100-216
Range on HMM: 102-228/298
Sequence Identity: 45% (59 aa)

ESL--VKKIMWQVLKGVEFCHQHNVIHRDVKPENILISK---------RGVVKICDFGFARAIA--PPGEAYTDYVATRWYRAPELLVGDTNYGRAVDVW
|.   .|.|| |.|.| ...| |.  |||.|||||....         ....||.||| .| |   ||   ||||| ||||||||.|  .|.|   .|.|
ENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPP---YTDYVSTRWYRAPECLLRCTYYNSPMDIW

AIGCLFSEMLTGEPLFPGESDIDQLYLITK
|.|| . |  .  ||||| | |||.. |.|
AVGCIMYELYMLRPLFPGSSEIDQIFKICK
Kinase AqueK107.AA RCK 4-84 36 2e-23 70.94 In-house 1-83 (298) Show / Hide 
Range on Protein: 4-84
Range on HMM: 1-83/298
Sequence Identity: 36% (31 aa)

YENLGLVGEGSYGMVMKCRHKDSSQLVAIKKFLETENDRMVKKIALREVRMLKQLR-HENLVNLIEVFRRKK--RLYLVFEFVD
|  .  .|.|.|| ||| . |.. ..|||||   ..       . |||.. |. |  |.|...|.||.| ..  .||.|||..|
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK-QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMD
Kinase AqueK107.AA Pkinase_Tyr 4-199 30 1.2e-22 77.28 Pfam 1-212 (270) Show / Hide 
Range on Protein: 4-199
Range on HMM: 1-212/270
Sequence Identity: 30% (66 aa)

YENLGLVGEGSYGMVMKCRHK----DSSQLVAIKKFLETENDRMV--KKIALREVRMLKQL-RHENLVNLIEVFR-RKKR--LYLVFEFVDHTALDE-LD
 . .   |||..|.|.|.. |    .  . ||.|.  |   .     ..  .||....||| .|.|.|.|. |   ...   .|.|.|.. |  |.. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KY---PSGADESLVKKIMWQVLKGVEFCHQHNVIHRDVKPENILISKRGVVKICDFGFARAIAPPGEAYTDYVAT-------RWYRAPELLVGDTNYGRA
|    .   . .   .. ||. || |. ...| ||||.   |.|... .|||||||| ||.|    . |  |...       .|. ||| .     .  .
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYY-YRKRGGGKLPIKWM-APECINYGK-FTTK

VDVWAIGCLFSEMLT-GE
 |||. | |  |..| ||
SDVWSFGVLMWEIFTYGE
Kinase AqueK107.AA TyrKc 4-287 22 2.2e-17 58.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-287
Range on HMM: 1-280/280
Sequence Identity: 22% (73 aa)

YENLGLVGEGSYGMVMKCRHKDSSQLVAIKKFLETENDRMVKKIALREVRMLKQL--RHENLVNLIEVFRRK-------KRLYLVFEFVDHTALDELDKY
 . .   ||| .| |.|.. |   . ||.|.  |       ..  .|| |....|  .|.|.|.|. | . .       . |..|.|...| .|..  ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

PSG-ADESLVKKIMWQVLKGVEFCHQHNVIHRDVKPENILISKRGVVKICDFGFARAIAPP------GEAYT------DY--VATRWYRAPELLVGDTN-
. .    .   ...||. .| |. |..|.||||    |.|......|||.||| .|.|         .. |.          .  ||. ||| .  ... 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI--NYGK

YGRAVDVWAIGCLFSEMLT-GEPLFPG-----ESDIDQLYLITKCFGNLIARH----REVFSRNPLFIGMRLPEAREIQPFERRYHRLSPAAMDIIKWSL
.  . |||. | .  |..| |..  ||      |... . .. . .   .  .                           |     . ...  .|.|.  
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------F----VCCPDEMYQIMKQCW

RLDPADRPTCTQLLKHELF
. ||.|||| ...  ||.|
HEDPEDRPTFSEI--HECF
Kinase AqueK107.AA CDK7 260-287 35 3.4e-05 9.32 In-house 261-288 (288) Show / Hide 
Range on Protein: 260-287
Range on HMM: 261-288/288
Sequence Identity: 35% (10 aa)

AMDIIKWSLRLDPADRPTCTQLLKHELF
..| ..  . ..|  | |||| ||.. |
LLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase AqueK107.AA CDK 268-287 40 8.7e-05 11.06 In-house 265-284 (284) Show / Hide 
Range on Protein: 268-287
Range on HMM: 265-284/284
Sequence Identity: 40% (8 aa)

LRLDPADRPTCTQLLKHELF
| .||. | ...| |.|. |
LCYDPKKRISAEQALQHPYF
Kinase AqueK107.AA RCK 255-287 30 0.000576 8.15 In-house 266-298 (298) Show / Hide 
Range on Protein: 255-287
Range on HMM: 266-298/298
Sequence Identity: 30% (10 aa)

RLSPAAMDIIKWSLRLDPADRPTCTQLLKHELF
..|. ......  |. ||  |.|  |.|.|  |
NCSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase AqueK107.AA MAPK 247-287 28 0.000668 9.12 In-house 284-328 (328) Show / Hide 
Range on Protein: 247-287
Range on HMM: 284-328/328
Sequence Identity: 28% (13 aa)

QPFERRYHR----LSPAAMDIIKWSLRLDPADRPTCTQLLKHELF
.|.|  .       .| | | ..  | .|| .| |  . | |. |
KPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase AqueK107.AA CDC2 256-287 31 0.002258 5.64 In-house 270-301 (301) Show / Hide 
Range on Protein: 256-287
Range on HMM: 270-301/301
Sequence Identity: 31% (10 aa)

LSPAAMDIIKWSLRLDPADRPTCTQLLKHELF
| | ..|...  |..||..| .  . |.|  |
LDPEGIDLLMQMLQYDPQKRISAKEALQHPYF