Gene AqueK108 (A.queenslandica)

AqueK108

Species: A.queenslandica
Alias: AqueK108
External Links:
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
AqueK108.AA Protein None 369 None Fasta, JSON
AqueK108.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of AqueK108.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK108.AA CK2 36-321 75 3.6e-226 683.35 In-house 1-288 (288) Show / Hide 
Range on Protein: 36-321
Range on HMM: 1-288/288
Sequence Identity: 75% (218 aa)

FQLVCKLGRGKYSEVFEGISVATNEKV--VIKVLKPVKKKKIKREIKILENLRGGPNIINLIDVVKDPWSRTPALVFEHVNNTDFKKLYTSLTDFDIRYY
.... |.|||||||||||| . .|||.  |||.|||||||||||||||||||.||||||.|.|.|||| |..||||||.||||||..||  |||.|||||
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

LYELLKALDYAHSMGIMHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPNQEYNVRVASRYFKGPELLVDLQEYDYSLDMWSFGCMLASMIFKKEPFFHGH
..||||||||.||||||||||||||.|||||.||||||||||||||||.|.|||||||||.|||||||| | |||||||||.|||.||||||||||||||
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

DNYDQLVRIGKVLGTEELYEYIDRYKIDLDPRFSDTLGRHSRKRWERYVHGENQHLVSREALDLLDKLLRYDHRERLSAKEAMGHPYF
|||||||.| ||||||.||.|.|.|.|.|||.|.| ...|..|.|||..| ||.||.. ||.|.|||.||||| ||..|||||.||||
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase AqueK108.AA CMGC 36-321 20 2.7e-96 316.94 In-house 1-513 (513) Show / Hide 
Range on Protein: 36-321
Range on HMM: 1-513/513
Sequence Identity: 20% (105 aa)

FQLVCKLGRGKYSEVFEGIS--------------VATNEKVVIKVLKPVKKKKIK---------------REIKILENLR----------------GGPN
.. . |.|.| |..|....                 |||.| || .| .. ...                ||||||..|.                  .|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IINLIDVVKDPWSRTP---------------ALVFEHVNNTDFKKLYT-----------SLTDFD------------IRYYL------YELLKALD--YA
|..|.|..... |...                ||||.. .. .. ..             |..              |.|..      | .|..|.  | 
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSMG--IMHRDVKPHNVMIDHEQRK-------------------LRLIDWGLAEFYHPN----------------------QEYNVRVASRYFKGPELLV
||..  |.||| || |..|.|. .                    |...|.||| .|||.                      . |  .|..|. . ||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

DL---------QEYDYSLDMWSFGCMLASM-------IFKKEPFFHGHDN-----------YDQLVRIGKVLG------------------TEELYEYID
           ..|... ||||.||..| |       ||...|.|.||..           .||| .| ||||                  .|| ...|.
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

RYKIDLDPR----------FSDT----------LGRHSRKRWERYVHGENQ------------------------------HLVSREALDLLDKLLRYDH
 .  ...|           .|.           .... .| |.. . . .                               .. . .|.|||.|.|.||.
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

RERLSAKEAMGHPYF
 .|..|..|. ||||
DKRITAEQALQHPYF
Kinase AqueK108.AA Pkinase 36-321 25 1e-85 295.9 Pfam 1-293 (293) Show / Hide 
Range on Protein: 36-321
Range on HMM: 1-293/293
Sequence Identity: 25% (79 aa)

FQLVCKLGRGKYSEVFEGISVATNEKVVIKVLKPVKKKKIKR-------EIKILENLRGGPNIINLIDVVKDPWSRTPALVFEHVNNT----DFK-----
.... |.|.| ...|.... . |...|..|..| ...|. |.       ||.|. .| . |||. |.|.. |  .. . .|.|.....    | .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

KLYTSL--TDFDIRYYLYELLKALDYAHSMGIMHRDVKPHNVMIDHEQRK---LRLIDWGLAEF--YHPNQEYNVRVASRYFKGPELLVDLQEYDYSLDM
. ....  .. ... |.|..|..|.| |||||.|||.|| |..||..      ....|.|||..  | .|. ..... ....  ||.. . |.|... ||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSFGCMLASMIFKKEPFFHG---HDNYDQLVRIGKVLGTEELYEYIDRYKIDLDPRFSDTLGRHSRKRWERYVHGENQHLVSREALDLLDKLLRYDHRER
||.||.|. |.... || .    .. .||...| ...|..  ...   . | ... |..   .          | .. |..|.|..|.....|..|  .|
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--------F-HWTF-HNWSEECKDFIKWCLCKDPKKR

LSAKEAMGHPYF
..|.... ||.|
PTAEQILQHPWF
Kinase AqueK108.AA S_TKc 36-321 24 5.9e-76 259.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 36-321
Range on HMM: 1-231/231
Sequence Identity: 24% (76 aa)

FQLVCKLGRGKYSEVFEGISVATNEKVVIKVLKPVKKKKIKREIKILENLRGGPNIINLIDVVKDPWSRTPALVFEHVNN--TDFKKLYTS---------
.... |.|.| ...|. .. . |...| ||..|    ..|.|||.||..  . |||..|.||  |       .|.|....   | ...  .         
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LTDFDIRYYLYELLKALDYAHSMGIMHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPNQEYNVRVASRYFKGPELLVDLQEYDY-SLDMWSFGCMLASMI
..  ..|.|.|....||.| ||.||.|||.|| |...|.    . ..| ||| ..      .  . ....  ||.|     |.. . |.||.||.|. |.
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

FKKEPFFHGHDNYDQLVRIGKVLGTEELYEYIDRYKIDLDPRFSDTLGRHSRKRWERYVHGENQHLVSREALDLLDKLLRYDHRERLSAKEAMG------
  . ||        |. .. |..|                                           |.||.|...|.|..| ..|..| ||.       
CGYPPFP-------QMQMMFKKIG-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HPYF
 ||.|
CHPWF
Kinase AqueK108.AA CDK 36-321 27 7e-58 183.69 In-house 1-284 (284) Show / Hide 
Range on Protein: 36-321
Range on HMM: 1-284/284
Sequence Identity: 27% (90 aa)

FQLVCKLGRGKYSEVFEGISVATN-----EKVVIKVLK-PV-----KKKKIK----REIKILENLRGGPNIINLIDVVKDP---------WSRTPALVFE
.. ..|.|.| | .|. ...  |.     . | .| ..        .|  .     |||..| .|   |||..|.||. .          . ..  .|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

HVNNTDFKKLYTSLTDFDIRYYLYELLKALDYAHSMGIMHRDVKPHNVMIDHEQR----KLRLIDWGLAEFYH-------PNQEYNVRVASRYFKGPELL
..  .| ||.        |. |.. ||..|.| || .||||| || | .|..       .| . | |||  ..       ||..|  .|  .    ||||
YM-DHDLKKYMD------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELL

VDLQEYD--YSLDMWSFGCMLASMIF--KKEPFFHGHDNYDQLVRIGKVLGT--EELYEYIDRYKIDLDPRFSDTLGRHSRKRWERYVHGENQHLVSREA
   ..|.   . ||||.|| .| |.    ..|.|.|    ||| .| ...||  |.    .  .                                    
LGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------------

LDLLDKLLRYDHRERLSAKEAMGHPYF
 |||.|.| ||   |.||..|. ||||
-DLLNKMLCYDPKKRISAEQALQHPYF
Kinase AqueK108.AA CAMK 41-229 18 4.3e-50 159.21 In-house 1-334 (425) Show / Hide 
Range on Protein: 41-229
Range on HMM: 1-334/425
Sequence Identity: 18% (63 aa)

KLGRGKYSEVFEGISVATN------------EKVVIKVLK-------------------------------PVKKKKIKREIKILENLRG------GPNI
.|||| ...|...|   |.            .|| ||...                               |...|...|||.|. .|.|       |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

INLIDVVK--------DPWS-RTPA----------LVF---EHVNNT----D-FKKLYTS-----------------LTDFDIRYYLYELLKALDYAHSM
|.|..|          .. .               .|.   |.. .     | | ..                    .|  . |.|   .. |..| ||.
IKLYEVYEDPHYFKNTND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

GIMHRDVKPHNVMIDHEQ----------------RKLRLIDWGLAEFYHP------------------------NQEYNVRVASRYFKG-PELLVD----
.|.||| || |...|.                   .. .||.|.| .. |                        .| .. .. . ..   ||.|      
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------LQEYDYSLDMWSFGCMLASMIFKKEPF
          . |... |||| |..|  |   . ||
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF
Kinase AqueK108.AA CDC2 36-321 30 5.2e-47 142.21 In-house 1-301 (301) Show / Hide 
Range on Protein: 36-321
Range on HMM: 1-301/301
Sequence Identity: 30% (96 aa)

FQLVCKLGRGKYSEVFEGISVATNEKVVIKVLKPVKKKKIK--------REIKILENLRGGPNIINLIDVVKDPWSRTPALVFEHVNNTDFKKLYT----
.| . |.| | | .|. .. . ||. |..|  . ..             ||| .| .|.  |||. | ||..    .   .||| . . | ||.      
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIR-LEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYL-DMDLKKYMDMSIP

---SLTDFDIRYYLYELLKALDYAHSMGIMHRDVKPHNVMIDHEQRKLRLIDWGLA-EFYHPNQEYN--VRVASRYFKGPELLVDLQEYDYSLDMWSFGC
   ...   .. |.| .|..... |...||||| || |  || . . ... | |||  |  |  .|     |  .    ||.|   . |. . ||||.||
KNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC

MLASM-IF-KKEPFFHGHDNYDQLVRIGKVLGT--EELYEYIDRYKIDLDPRFSDTLGRHSRKRWERYVHG----ENQHLVSREALDLLDKLLRYDHRER
 .| | .   |.|.|||    ||| .| ..|||  |. .. .. .     | .  | .|  ..  ....       ||  .  |..|||...|.||   |
IFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQL-----PDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKR

LSAKEAMGHPYF
.|||||. ||||
ISAKEALQHPYF
Kinase AqueK108.AA Ciliate-E2 36-321 16 9.7e-43 144.53 In-house 1-365 (365) Show / Hide 
Range on Protein: 36-321
Range on HMM: 1-365/365
Sequence Identity: 16% (70 aa)

FQLVCKLGRGKYSEVFEG--ISV---------------------ATNEKVVIKVLKPVKKKKIKREIKILENLRGG---------------PNIINLIDV
. .. |.|.| .. |...  ..|                     ... .. .|..|. ... ||.||.|.  .. .               ||||.....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VKDPWSRTPALVFEHVNNTDFKKLYT--------------SLTDFDIRYYLYELLK---------------ALDYAHSMG-IMHRDVKPHNVMIDHEQRK
 ..    .  ||.| ..  | ...                ..|.. |.|. ...|.               || | || . |.||| || |...      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

LRLIDWGLAEFYHPNQE--------------------------------YNVRVASRYFKGPELLVDLQE--------YDYSLDMWSFGCMLASMIFKKE
. .||.||. .|.....                                .|  . . ... || |   ..        |||. |.||.|..|  |.|.| 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFFHGHDNYDQLVRIGKVLGTEELYEYIDRYKIDLDPRFSDTLGRHSRKRWERYVHGENQHL---------------------------VSREALDLLDK
||                                                       ..|..                           .| |. ||. |
PF-------------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKK

----LLRYDHRERLS-AKEAMGHPYF
    .| .|  .|.. ..... ||.|
FGKRMLQKDPEKRITGWEQILNHPWF
Kinase AqueK108.AA ERK7 36-321 29 7.6e-38 126.81 In-house 1-292 (292) Show / Hide 
Range on Protein: 36-321
Range on HMM: 1-292/292
Sequence Identity: 29% (88 aa)

FQLVCKLGRGKYSEVFEGISVATNEKVVIKVL-----KPVKKKKIKREIKILENLRGGPNIINLIDVVKDPWSRTPALVFEHVNNTDFKKLYT---SLTD
...  .||.| |  |   .   | . | .|        ..   .  ||| .| .... |||| ||.|..    |   ||||.  .||          | |
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFM-ETDLHAVIRKGNILKD

FDIRYYLYELLKALDYAHSMGIMHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPNQEYNVR-------VASRYFKGPELLVDLQEYDYSLDMWSFGCMLA
   .| .| ||.|. | ||  ..|||.|| |...| | . ... | |||      .||.         || | .  || |.  ..|    |||| || |.
IHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECM-VKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILG

SMIFKKEPFFHGHDNYDQLVRIGKVLGTEELYEYIDRYKIDLDPRFSDTLGRHSRKRWERYVHGENQHLVSREALDLLDKLLRYDHRERLSAKEAMGHPY
 |. .| | | |    .|. .| ....    .| |   . ..     . .... ||  .  . .      . .|.||| .|| .  ..||.|..|. |||
EMLRGK-PMFPGTSTMNQIEKILETIPKPT-QEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQ-----CCDDAIDLLKRLLVFNPKKRLTAEQALQHPY

F
 
V
Kinase AqueK108.AA CDK-Unclassified 36-248 30 3.2e-36 116.57 In-house 1-257 (324) Show / Hide 
Range on Protein: 36-248
Range on HMM: 1-257/324
Sequence Identity: 30% (78 aa)

FQLVCKLGRGKYSEVFEGISVATNEKVVIKVLKPVKKKK----------------IKREIKILENLRGGPNIINLIDVV--KDPWSRTPA---------L
    ||.|.| . .|. .|   |. .| || .  |. ||                 .|||..| |.    ||| ..|..   |. |. |.         .
YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIM-VNNKKGNKCKHILPLLNSKITDQREISCLQNCNHM-NIIKFMDMHYDHDRCSKNPYYDNLHPSFYM

VFEHVNNTD---FKKLYTSLTDFDIRYYLYELLKALDYAHSMGIMHRDVKPHNVMIDHEQ----RKLRLIDWGLAEFYH-------------PNQEYNVR
| | .  |     .    .|   .|| ..  .|. . | |. .|||||.|| |.||..       .| ..| |.| ||              |.|.| . 
VMEYMPYTWYNQLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYSTQ

VASRYFKGPELLVDLQEYDYSLDMWSFGCMLASMIFKKEPFFHGHDNYDQLVRIGKVLGT
|. |  . ||||   ..||.  |.||||| .| . |.. | | |    .|.  | |.|||
VSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEW-FQGKPIFQGRTEIEQMHHIFKMLGT
Kinase AqueK108.AA RCK 36-248 30 1.1e-34 107.21 In-house 1-232 (298) Show / Hide 
Range on Protein: 36-248
Range on HMM: 1-232/298
Sequence Identity: 30% (73 aa)

FQLVCKLGRGKYSEVFEGISVATNEKVVIKVLKPVKKKKIK-----REIKILENLRGGPNIINLIDVVKDPWSRTPALVFEHVNN------TDFKKLYTS
 |.. .||.| |..|...... |.|.| || .|  | ....     |||| |  |   ||||.|..|..|  ... ..|||.. .       |||.  . 
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK-QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKY

LTDFD--IRYYLYELLKALDYAHSMGIMHRDVKPHNVMIDHE--------QRKLRLIDWGLA-EFY--HPNQEYNVRVASRYFKGPELLVDLQEYDYSLD
|. .   |. ..| .|..|.. |. |..|||.|| | |.  .        |  . ..| ||. |..  .|. .|   | .|.   ||.|   . |.. .|
LPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDY---VSTRWYRAPECLLRCTYYNSPMD

MWSFGCMLASMIFKKEPFFHGHDNYDQLVRIGKVLGT
.|..||  .  .  . | | | .  ||.  | ||.||
IWAVGCIMY-ELYMLRPLFPGSSEIDQIFKICKVMGT
Kinase AqueK108.AA CDK5 36-248 33 1e-31 97.1 In-house 1-218 (287) Show / Hide 
Range on Protein: 36-248
Range on HMM: 1-218/287
Sequence Identity: 33% (75 aa)

FQLVCKLGRGKYSEVFEGISVATNEKVVIKVLKPVKK-----KKIKREIKILENLRGGPNIINLIDVVKDPWSRTPALVFEHVNNTDFKKLYTSLTDFD-
.. . |.| | |  |. .    | | | .|  .             ||| .|  |.  .||. |.||.     .   ||||.. . | ||   |... . 
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELK-HKNIVRLHDVIHS--EKKLTLVFEFCDQ-DLKKYMDSCNG-EM

----IRYYLYELLKALDYAHSMGIMHRDVKPHNVMIDHEQRKLRLIDWGLAE-FYHPNQEYNVRVASRYFKGPELLVDLQEYDYSLDMWSFGCMLASMIF
    |....| ||| | . |.  ..||| || | .|  .  .|.| | |||  |  | . |   |    .  |  |   . |  | |||| || .| |. 
DMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNG-ELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMAN

KKEPFFHGHDNYDQLVRIGKVLGT
   | | | |  ||| || |..||
AGRPLFPGNDVEDQLKRIFKIMGT
Kinase AqueK108.AA CDK5 295-321 51 1.3e-11 32.51 In-house 261-287 (287) Show / Hide 
Range on Protein: 295-321
Range on HMM: 261-287/287
Sequence Identity: 51% (14 aa)

LDLLDKLLRYDHRERLSAKEAMGHPYF
.||| |.|...  .|.|||.|. ||||
MDLLQKMLQCNPNQRISAKAALHHPYF
Kinase AqueK108.AA RCK 291-321 38 2.1e-10 28.94 In-house 268-298 (298) Show / Hide 
Range on Protein: 291-321
Range on HMM: 268-298/298
Sequence Identity: 38% (12 aa)

SREALDLLDKLLRYDHRERLSAKEAMGHPYF
| ....|. |.|..|  .| .|..|  ||||
SQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase AqueK108.AA TyrKc 36-278 17 2.7e-10 -56.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 36-278
Range on HMM: 1-280/280
Sequence Identity: 17% (51 aa)

FQLVCKLGRGKYSEVFEGISVATNEKVVIKVLKPVKKKKIKREIKILENL-RGGPNIINLIDVVKDP-----WSRTPALVFEHVNNTDFKKL--YTS--L
 .|  |||.| . ||..|.     ..| .|.||. ... . ||..|. .|    |||..|. |. ..      .  . .|.|.. . | |.   ..   |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

TDFDIRYYLYELLKALDYAHSMGIMHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPN-------QEYNVRV--ASR-----YFKGPELLVDLQEYDYSLD
.  |  .. .   .  .| ||... |||    |.......   .  | ||. . .         . | ..    ..         || . .  ..    |
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSD

MWSFGCML---ASMIFKKEPF-----FHGHDNYDQLVRI---GKVLG---------TEELYEYIDR---YKIDLDPRFSDTLGRHSRKRW
 |||| ..    .   .  |          . . .. .     .            ..|.|. . .   .. .  |.||.      ....
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HECF
Kinase AqueK108.AA CAMK 290-321 34 6.5e-10 27.39 In-house 394-425 (425) Show / Hide 
Range on Protein: 290-321
Range on HMM: 394-425/425
Sequence Identity: 34% (11 aa)

VSREALDLLDKLLRYDHRERLSAKEAMGHPYF
|| |. ||. |.|..|  .|....... || .
VSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK108.AA APH 134-181 31 0.00043 14.84 Pfam 159-207 (248) Show / Hide 
Range on Protein: 134-181
Range on HMM: 159-207/248
Sequence Identity: 31% (16 aa)

LYELLKALDYAHSMGIMHRDVKPHNVMIDHEQRKLR---LIDWGLAEFYHP
|.. |.|.      ...|.|..|.|||.|  ... |   .|||. | . .|
LWAWLEAHWP--PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWGDP
Kinase AqueK108.AA Pkinase_Tyr 36-95 30 0.00059 14.02 Pfam 1-70 (270) Show / Hide 
Range on Protein: 36-95
Range on HMM: 1-70/270
Sequence Identity: 30% (21 aa)

FQLVCKLGRGKYSEVFEGISV----ATNEKVVIKVLKP---VK---KKKIKREIKILENLRGGPNIINLI
 ..  |||.| . ||..|.       |. .| .|.||.    .   ...  ||.||. .|   |||..|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY
Kinase AqueK108.AA CDK-Unclassified 295-321 22 0.001309 7.59 In-house 298-324 (324) Show / Hide 
Range on Protein: 295-321
Range on HMM: 298-324/324
Sequence Identity: 22% (6 aa)

LDLLDKLLRYDHRERLSAKEAMGHPYF
....  .. |.  .|... |.  ||.|
NNCEFQMVMYQPYNRWKCMEILQHPWF